#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P40029 uniprotkb:O13559 intact:EBI-11441|ensemblfungi:YER042W|uniprotkb:D3DLU2 intact:EBI-29562|uniprotkb:D6VZ97|ensemblfungi:YLR466W psi-mi:msra_yeast(display_long)|uniprotkb:MXR1(gene name)|psi-mi:MXR1(display_short)|uniprotkb:Protein-methionine-S-oxide reductase(gene name synonym)|uniprotkb:"Peptide-methionine (S)-S-oxide reductase"(gene name synonym)|uniprotkb:YER042W(locus name) psi-mi:yrf14_yeast(display_long)|uniprotkb:YRF1-4(gene name)|psi-mi:YRF1-4(display_short)|uniprotkb:YLR466W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6313902|imex:IM-14275-1 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER042W(gene)|ensemblfungi:YER042W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008113"("peptide-methionine (S)-S-oxide reductase activity")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036456"("L-methionine-(S)-S-oxide reductase activity")|rcsb pdb:3PIL|rcsb pdb:3PIM|rcsb pdb:3PIN|refseq:NP_010960.1|sgd:S000000844|interpro:IPR002569(Methionine sulphoxide reductase A)|interpro:IPR036509|mint:P40029 sgd:S000004458|refseq:NP_013571.3|dip:DIP-8268N|mint:O13559|ensemblfungi:YLR466W(gene)|ensemblfungi:YLR466W_mRNA(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:qa4BOix8taLsa3wYUJp340iVeGs559292 rogid:ey5kymsCTbmjbuUW/WCusawJSSM559292 intact-crc:24EEDDAD86BAFE3A|rigid:OR2OPdTQmmYnDIb5ZBr1L8X/Gd0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32565 uniprotkb:O13563 intact:EBI-15919|uniprotkb:D6VVK9|ensemblfungi:YIL075C intact:EBI-32948|uniprotkb:D6VZ57|ensemblfungi:YLR421C psi-mi:rpn2_yeast(display_long)|uniprotkb:RPN2(gene name)|psi-mi:RPN2(display_short)|uniprotkb:SEN3(gene name synonym)|uniprotkb:YIL075C(locus name) psi-mi:rpn13_yeast(display_long)|uniprotkb:RPN13(gene name)|psi-mi:RPN13(display_short)|uniprotkb:DAQ1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 13(gene name synonym)|uniprotkb:YLR421C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6313913|imex:IM-14275-2 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012190.1|sgd:S000001337|ensemblfungi:YIL075C(gene)|ensemblfungi:YIL075C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016642(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit)|interpro:IPR035266|interpro:IPR040623|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4ADY|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|dip:DIP-4638N|mint:P32565 sgd:S000004413|refseq:NP_013525.3|mint:O13563|dip:DIP-4637N|ensemblfungi:YLR421C(gene)|ensemblfungi:YLR421C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR006773(Adhesion regulating molecule)|interpro:IPR038633|interpro:IPR044868|rcsb pdb:2Z4D|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30 psi-mi:"MI:0469"(intact) crc64:881E78EBC6BD934F crc64:752E8A12DC3799D4 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XKuDty+1gX7/pz7ZtNmYK4Pfkc8559292 rogid:UDb5Hp4hH3QQ5iX7/9BtQVBO0FA559292 intact-crc:81FA4180F1211317|rigid:imZT6V78rwCF59NU1MtPGaPCbys false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38009 uniprotkb:O94742 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 intact:EBI-31337|uniprotkb:D6VSZ2|ensemblfungi:YDR363W-A psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:sem1_yeast(display_long)|uniprotkb:SEM1(gene name)|psi-mi:SEM1(display_short)|uniprotkb:DSH1(gene name synonym)|uniprotkb:YDR363W-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6313924|imex:IM-14275-3 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N refseq:NP_010651.3|sgd:S000007235|dip:DIP-8754N|mint:O94742|ensemblfungi:YDR363W-A(gene)|ensemblfungi:YDR363W-A_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030447"(filamentous growth)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0072742"(SAGA complex localization to transcription regulatory region)|interpro:IPR007834(DSS1/SEM1)|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3T5V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4TRQ|rcsb pdb:5A5B|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5UBP|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30 psi-mi:"MI:0469"(intact) crc64:8ABA71761B512242 crc64:B66B578ABB01E672 figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 rogid:jW26dMSkSwiSL4WsgtoWcg98j9A559292 intact-crc:2B8C1254BDC560F1|rigid:EurrBRFNfkwRMAz86vH33PnYXXQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00045 uniprotkb:P20447 intact:EBI-2052005|uniprotkb:D3DLL0|ensemblfungi:YEL039C intact:EBI-5608|uniprotkb:D6VU66|ensemblfungi:YGL078C psi-mi:cyc7_yeast(display_long)|uniprotkb:CYP3(gene name synonym)|uniprotkb:CYC7(gene name)|psi-mi:CYC7(display_short)|uniprotkb:Cytochrome c hypoxic isoform(gene name synonym)|uniprotkb:YEL039C(locus name) psi-mi:dbp3_yeast(display_long)|uniprotkb:YGL078C(locus name)|uniprotkb:DBP3(gene name)|psi-mi:DBP3(display_short)|uniprotkb:DEAD box protein 3(gene name synonym)|uniprotkb:Helicase CA3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6313935|imex:IM-14275-4 author score:97.40 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010875.1|sgd:S000000765|dip:DIP-7178N|mint:P00045|ensemblfungi:YEL039C(gene)|ensemblfungi:YEL039C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070469"(respirasome)|interpro:IPR002327(Cytochrome c, class IA/ IB)|interpro:IPR009056(Cytochrome c, monohaem)|interpro:IPR036909|rcsb pdb:1YEA|rcsb pdb:1YEB|rcsb pdb:1YTC|rcsb pdb:3CXH|reactome:R-SCE-111457|reactome:R-SCE-3299685|reactome:R-SCE-5620971|reactome:R-SCE-611105 sgd:S000003046|refseq:NP_011437.3|dip:DIP-2668N|mint:P20447|ensemblfungi:YGL078C(gene)|ensemblfungi:YGL078C_mRNA(transcript)|go:"GO:0000464"("endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oKeKcvx2MckESCz9OExgMCNlfWE559292 rogid:9ltHUfhcU8nfN3bxsmkabo8A2L4559292 intact-crc:09614AFB3E6DC27B|rigid:uf9+OQQKTj32Ae2EKfRQlfWs4Pc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00045 uniprotkb:P23202 intact:EBI-2052005|uniprotkb:D3DLL0|ensemblfungi:YEL039C intact:EBI-20138|uniprotkb:D6W0W3|ensemblfungi:YNL229C psi-mi:cyc7_yeast(display_long)|uniprotkb:CYP3(gene name synonym)|uniprotkb:CYC7(gene name)|psi-mi:CYC7(display_short)|uniprotkb:Cytochrome c hypoxic isoform(gene name synonym)|uniprotkb:YEL039C(locus name) psi-mi:ure2_yeast(display_long)|uniprotkb:URE2(gene name)|psi-mi:URE2(display_short)|uniprotkb:Disulfide reductase(gene name synonym)|uniprotkb:Glutathione peroxidase(gene name synonym)|uniprotkb:N1165(orf name)|uniprotkb:YNL229C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6313946|imex:IM-14275-5 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010875.1|sgd:S000000765|dip:DIP-7178N|mint:P00045|ensemblfungi:YEL039C(gene)|ensemblfungi:YEL039C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070469"(respirasome)|interpro:IPR002327(Cytochrome c, class IA/ IB)|interpro:IPR009056(Cytochrome c, monohaem)|interpro:IPR036909|rcsb pdb:1YEA|rcsb pdb:1YEB|rcsb pdb:1YTC|rcsb pdb:3CXH|reactome:R-SCE-111457|reactome:R-SCE-3299685|reactome:R-SCE-5620971|reactome:R-SCE-611105 refseq:NP_014170.1|sgd:S000005173|ensemblfungi:YNL229C(gene)|ensemblfungi:YNL229C_mRNA(transcript)|mint:P23202|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0010044"(response to aluminum ion)|go:"GO:0032447"(protein urmylation)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR017298(Prion URE2)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:1G6W|rcsb pdb:1G6Y|rcsb pdb:1HQO|rcsb pdb:1JZR|rcsb pdb:1K0A|rcsb pdb:1K0B|rcsb pdb:1K0C|rcsb pdb:1K0D|go:"GO:0003714"(transcription corepressor activity)|dip:DIP-1308N psi-mi:"MI:0469"(intact) - crc64:2C628976034B0F1C figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oKeKcvx2MckESCz9OExgMCNlfWE559292 rogid:jjsWygBsEp8axNurMa3pxPMQJ2k559292 intact-crc:EE666AAFE5168252|rigid:QZFGRr0xfSr0FopRnRUY1EPB6Bc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00447 uniprotkb:P48564 intact:EBI-17645|uniprotkb:D3DKV3|ensemblfungi:YHR008C intact:EBI-2046889|uniprotkb:D6W0P8|ensemblfungi:YNL295W psi-mi:sodm_yeast(display_long)|uniprotkb:SOD2(gene name)|psi-mi:SOD2(display_short)|uniprotkb:YHR008C(locus name) psi-mi:mrx6_yeast(display_long)|uniprotkb:Mitochondrial organization of gene expression protein 6(gene name synonym)|uniprotkb:MRX6(gene name)|psi-mi:MRX6(display_short)|uniprotkb:N0462(orf name)|uniprotkb:YNL295W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6313957|imex:IM-14275-6 author score:99.26 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011872.1|sgd:S000001050|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0030145"(manganese ion binding)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR001189(Manganese and iron superoxide dismutase)|interpro:IPR019831|interpro:IPR019832|interpro:IPR019833|interpro:IPR036314|interpro:IPR036324|rcsb pdb:3BFR|rcsb pdb:3LSU|rcsb pdb:3RN4|rcsb pdb:4E4E|rcsb pdb:4F6E|reactome:R-SCE-3299685|ensemblfungi:YHR008C_mRNA(transcript)|ensemblfungi:YHR008C(gene)|dip:DIP-4905N|mint:P00447 sgd:S000005239|interpro:IPR014804(Mitochondrial protein Pet20)|refseq:NP_014104.1|mint:P48564|ensemblfungi:YNL295W(gene)|ensemblfungi:YNL295W_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0090144"(mitochondrial nucleoid organization)|go:"GO:1901858"(regulation of mitochondrial DNA metabolic process) psi-mi:"MI:0469"(intact) crc64:88A9391FBB31D06E - figure legend:tables S3 and S4|author-confidence:99.26|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:7J7jbmkndYD7x48Z0kFOpFJl2Eg559292 rogid:tn8uhrqTB1ab8+RUwgjWLjJ9b8w559292 intact-crc:9467528D6C122357|rigid:h4ekWUdjb8ZPgXhxJ9NQkCcKoqE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00447 uniprotkb:Q03370 intact:EBI-17645|uniprotkb:D3DKV3|ensemblfungi:YHR008C intact:EBI-36170|uniprotkb:D6VTA2|ensemblfungi:YDR479C psi-mi:sodm_yeast(display_long)|uniprotkb:SOD2(gene name)|psi-mi:SOD2(display_short)|uniprotkb:YHR008C(locus name) psi-mi:pex29_yeast(display_long)|uniprotkb:PEX29(gene name)|psi-mi:PEX29(display_short)|uniprotkb:Peroxin-29(gene name synonym)|uniprotkb:YDR479C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6313968|imex:IM-14275-7 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011872.1|sgd:S000001050|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0030145"(manganese ion binding)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR001189(Manganese and iron superoxide dismutase)|interpro:IPR019831|interpro:IPR019832|interpro:IPR019833|interpro:IPR036314|interpro:IPR036324|rcsb pdb:3BFR|rcsb pdb:3LSU|rcsb pdb:3RN4|rcsb pdb:4E4E|rcsb pdb:4F6E|reactome:R-SCE-3299685|ensemblfungi:YHR008C_mRNA(transcript)|ensemblfungi:YHR008C(gene)|dip:DIP-4905N|mint:P00447 refseq:NP_010767.1|sgd:S000002887|mint:Q03370|dip:DIP-5175N|ensemblfungi:YDR479C(gene)|ensemblfungi:YDR479C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032581"(ER-dependent peroxisome organization)|interpro:IPR010482(Integral peroxisomal membrane peroxin) psi-mi:"MI:0469"(intact) crc64:88A9391FBB31D06E crc64:C2EB849C36FB69EB figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:7J7jbmkndYD7x48Z0kFOpFJl2Eg559292 rogid:XirbTI20sgYx5DDsELcnS9RLxMw559292 intact-crc:F12B7CDFCBCDBCB1|rigid:GnzxP3TNCh18UgQcYQhgNUHi5HY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38328 uniprotkb:P00899 intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C intact:EBI-19575|uniprotkb:D3DLZ7|ensemblfungi:YER090W psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:trpe_yeast(display_long)|uniprotkb:TRP2(gene name)|psi-mi:TRP2(display_short)|uniprotkb:YER090W(locus name)|uniprotkb:Anthranilate synthase component I(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6313979|imex:IM-14275-8 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 refseq:NP_011014.1|sgd:S000000892|ensemblfungi:YER090W(gene)|ensemblfungi:YER090W_mRNA(transcript)|go:"GO:0000162"(tryptophan biosynthetic process)|go:"GO:0004049"(anthranilate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005950"(anthranilate synthase complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR005256(Anthranilate synthase component I)|interpro:IPR005801(Anthranilate synthase component I and chorismate binding protein)|interpro:IPR006805(Anthranilate synthase component I, N-terminal)|interpro:IPR015890(Chorismate binding, C-terminal)|interpro:IPR019999|dip:DIP-542N|mint:P00899 psi-mi:"MI:0469"(intact) crc64:D75C6BB8EC35EEDF crc64:FCC179C481DB3107 figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 rogid:Yv5Dfz3jlZgeOh+sHFzx7GTKZDs559292 intact-crc:1F70C3A6BF404A9C|rigid:DjB/Zt/mJePej9FufiyGro+MNdM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00899 uniprotkb:P41811 intact:EBI-19575|uniprotkb:D3DLZ7|ensemblfungi:YER090W intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:trpe_yeast(display_long)|uniprotkb:TRP2(gene name)|psi-mi:TRP2(display_short)|uniprotkb:YER090W(locus name)|uniprotkb:Anthranilate synthase component I(gene name synonym) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6313990|imex:IM-14275-9 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011014.1|sgd:S000000892|ensemblfungi:YER090W(gene)|ensemblfungi:YER090W_mRNA(transcript)|go:"GO:0000162"(tryptophan biosynthetic process)|go:"GO:0004049"(anthranilate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005950"(anthranilate synthase complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR005256(Anthranilate synthase component I)|interpro:IPR005801(Anthranilate synthase component I and chorismate binding protein)|interpro:IPR006805(Anthranilate synthase component I, N-terminal)|interpro:IPR015890(Chorismate binding, C-terminal)|interpro:IPR019999|dip:DIP-542N|mint:P00899 refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:FCC179C481DB3107 crc64:6A5E50BBEB02CB58 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Yv5Dfz3jlZgeOh+sHFzx7GTKZDs559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:0251726B745E9DCB|rigid:NcfsURDot0oG79VX22Q5pbax5+o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47039 uniprotkb:P00899 intact:EBI-25893|uniprotkb:D6VWC2|ensemblfungi:YJL060W intact:EBI-19575|uniprotkb:D3DLZ7|ensemblfungi:YER090W psi-mi:bna3_yeast(display_long)|uniprotkb:YJL060W(locus name)|uniprotkb:J1138(orf name)|uniprotkb:Biosynthesis of nicotinic acid protein 3(gene name synonym)|uniprotkb:BNA3(gene name)|psi-mi:BNA3(display_short)|uniprotkb:Kynurenine aminotransferase(gene name synonym) psi-mi:trpe_yeast(display_long)|uniprotkb:TRP2(gene name)|psi-mi:TRP2(display_short)|uniprotkb:YER090W(locus name)|uniprotkb:Anthranilate synthase component I(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314001|imex:IM-14275-10 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003596|refseq:NP_012475.3|mint:P47039|dip:DIP-6723N|ensemblfungi:YJL060W(gene)|ensemblfungi:YJL060W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0016212"(kynurenine-oxoglutarate transaminase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034276"(kynurenic acid biosynthetic process)|go:"GO:0047536"(2-aminoadipate transaminase activity)|go:"GO:0097053"(L-kynurenine catabolic process)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:3B46|reactome:R-SCE-71240|reactome:R-SCE-8964208|reactome:R-SCE-8964539 refseq:NP_011014.1|sgd:S000000892|ensemblfungi:YER090W(gene)|ensemblfungi:YER090W_mRNA(transcript)|go:"GO:0000162"(tryptophan biosynthetic process)|go:"GO:0004049"(anthranilate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005950"(anthranilate synthase complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR005256(Anthranilate synthase component I)|interpro:IPR005801(Anthranilate synthase component I and chorismate binding protein)|interpro:IPR006805(Anthranilate synthase component I, N-terminal)|interpro:IPR015890(Chorismate binding, C-terminal)|interpro:IPR019999|dip:DIP-542N|mint:P00899 psi-mi:"MI:0469"(intact) - crc64:FCC179C481DB3107 figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Fli6ip0tteNbMkQG9h7/IBow3ms559292 rogid:Yv5Dfz3jlZgeOh+sHFzx7GTKZDs559292 intact-crc:B62D9195D8BC7CAE|rigid:nk9FutkWX6qhWVPO6IvtoCUTkKs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39958 uniprotkb:P01123 intact:EBI-7517|uniprotkb:D3DM41|ensemblfungi:YER136W intact:EBI-29496|uniprotkb:D6VTJ2|ensemblfungi:YFL038C psi-mi:gdi1_yeast(display_long)|uniprotkb:YER136W(locus name)|uniprotkb:GDI1(gene name)|psi-mi:GDI1(display_short)|uniprotkb:SEC19(gene name synonym)|uniprotkb:Secretory pathway GDP dissociation inhibitor(gene name synonym) psi-mi:ypt1_yeast(display_long)|uniprotkb:YFL038C(locus name)|uniprotkb:YPT1(gene name)|psi-mi:YPT1(display_short)|uniprotkb:YP2(gene name synonym)|uniprotkb:Rab GTPase YPT1(gene name synonym)|uniprotkb:Transport GTPase YPT1(gene name synonym)|uniprotkb:Protein YP2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314034|imex:IM-14275-13 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011062.1|sgd:S000000938|mint:P39958|dip:DIP-785N|ensemblfungi:YER136W(gene)|ensemblfungi:YER136W_mRNA(transcript)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|rcsb pdb:1UKV|rcsb pdb:2BCG|rcsb pdb:3CPH|rcsb pdb:3CPI|rcsb pdb:3CPJ|reactome:R-SCE-6798695|reactome:R-SCE-8876198 refseq:NP_116615.1|sgd:S000001856|dip:DIP-2019N|mint:P01123|ensemblfungi:YFL038C(gene)|ensemblfungi:YFL038C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0061709"(reticulophagy)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1990261"(pre-mRNA catabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1UKV|rcsb pdb:1YZN|rcsb pdb:2BCG|rcsb pdb:3CUE|rcsb pdb:7KMT|reactome:R-SCE-162658|reactome:R-SCE-204005|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-8873719|reactome:R-SCE-8876198 psi-mi:"MI:0469"(intact) crc64:48CF8D45FC031772 crc64:F8C704F6BF2D227B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AkWsG1VUBGxajiAMw0e0mOljZ6s559292 rogid:IMz/iERXs1zvX+wgJ9x7Uk0ovQ8559292 intact-crc:96BAABEF02FD239E|rigid:XuDDMTsPY6T0xv/lB6G5LuHjHQQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01120 uniprotkb:P43588 intact:EBI-14838|uniprotkb:Q45U01|uniprotkb:D6W181|ensemblfungi:YNL098C intact:EBI-11219|uniprotkb:Q8J0T5|uniprotkb:D6VTN4|ensemblfungi:YFR004W psi-mi:ras2_yeast(display_long)|uniprotkb:RAS2(gene name)|psi-mi:RAS2(display_short)|uniprotkb:ASC1(gene name synonym)|uniprotkb:CTN5(gene name synonym)|uniprotkb:GLC5(gene name synonym)|uniprotkb:YNL098C(locus name)|uniprotkb:N2198(orf name) psi-mi:rpn11_yeast(display_long)|uniprotkb:YFR004W(locus name)|uniprotkb:RPN11(gene name)|psi-mi:RPN11(display_short)|uniprotkb:MPR1(gene name synonym)|uniprotkb:Protein MPR1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN11(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314012|imex:IM-14275-11 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014301.1|sgd:S000005042|go:"GO:0032880"(regulation of protein localization)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0071944"(cell periphery)|go:"GO:0097271"(protein localization to bud neck)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|reactome:R-SCE-9696273|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016236"(macroautophagy)|go:"GO:0019003"(GDP binding)|go:"GO:0030437"(ascospore formation)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|ensemblfungi:YNL098C(gene)|ensemblfungi:YNL098C_mRNA(transcript)|go:"GO:0000411"(positive regulation of transcription by galactose)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007265"(Ras protein signal transduction)|dip:DIP-2263N|mint:P01120 ensemblfungi:YFR004W(gene)|ensemblfungi:YFR004W_mRNA(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016559"(peroxisome fission)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070628"(proteasome binding)|go:"GO:1902906"(proteasome storage granule assembly)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4O8X|rcsb pdb:4O8Y|rcsb pdb:4OCL|rcsb pdb:4OCM|go:"GO:0070122"(isopeptidase activity)|rcsb pdb:4OCN|rcsb pdb:4OWP|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5U4P|rcsb pdb:5W83|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-5689901|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|refseq:NP_116659.1|sgd:S000001900|mint:P43588|dip:DIP-1573N psi-mi:"MI:0469"(intact) crc64:6CAAAC531EEAE92F crc64:9DDE8BD74890894D figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MJS2Zuw6xxrxaLE6r3omwm+2vm4559292 rogid:f3lAMY9siMcO2dAOfKvVrvKzfNM559292 intact-crc:5BA56E341303F868|rigid:JC4BtVgJCT2jTkBTYGXuxrsHe9Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01123 uniprotkb:P11076 intact:EBI-29496|uniprotkb:D6VTJ2|ensemblfungi:YFL038C intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W psi-mi:ypt1_yeast(display_long)|uniprotkb:YFL038C(locus name)|uniprotkb:YPT1(gene name)|psi-mi:YPT1(display_short)|uniprotkb:YP2(gene name synonym)|uniprotkb:Rab GTPase YPT1(gene name synonym)|uniprotkb:Transport GTPase YPT1(gene name synonym)|uniprotkb:Protein YP2(gene name synonym) psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314023|imex:IM-14275-12 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116615.1|sgd:S000001856|dip:DIP-2019N|mint:P01123|ensemblfungi:YFL038C(gene)|ensemblfungi:YFL038C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0061709"(reticulophagy)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1990261"(pre-mRNA catabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1UKV|rcsb pdb:1YZN|rcsb pdb:2BCG|rcsb pdb:3CUE|rcsb pdb:7KMT|reactome:R-SCE-162658|reactome:R-SCE-204005|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-8873719|reactome:R-SCE-8876198 refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 psi-mi:"MI:0469"(intact) crc64:F8C704F6BF2D227B crc64:796859026AC63CC0 figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IMz/iERXs1zvX+wgJ9x7Uk0ovQ8559292 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 intact-crc:D3A5EC3299A1D14A|rigid:RbOJtec238gTYmAduyUM9bLwj44 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12383 uniprotkb:P01123 intact:EBI-32166|uniprotkb:D6W1U3|ensemblfungi:YOL125W intact:EBI-29496|uniprotkb:D6VTJ2|ensemblfungi:YFL038C psi-mi:trm13_yeast(display_long)|uniprotkb:tRNA methylase 13(gene name synonym)|uniprotkb:TRM13(gene name)|psi-mi:TRM13(display_short)|uniprotkb:YOL125W(locus name) psi-mi:ypt1_yeast(display_long)|uniprotkb:YFL038C(locus name)|uniprotkb:YPT1(gene name)|psi-mi:YPT1(display_short)|uniprotkb:YP2(gene name synonym)|uniprotkb:Rab GTPase YPT1(gene name synonym)|uniprotkb:Transport GTPase YPT1(gene name synonym)|uniprotkb:Protein YP2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314056|imex:IM-14275-15 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014516.1|sgd:S000005485|interpro:IPR007871(Protein of unknown function DUF715)|interpro:IPR022776|interpro:IPR021721|mint:Q12383|interpro:IPR039044|ensemblfungi:YOL125W(gene)|ensemblfungi:YOL125W_mRNA(transcript)|go:"GO:0002128"(tRNA nucleoside ribose methylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008175"(tRNA methyltransferase activity)|go:"GO:0030488"(tRNA methylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052666"("tRNA (cytosine-2'-O-)-methyltransferase activity")|go:"GO:0106050"(tRNA 2'-O-methyltransferase activity) refseq:NP_116615.1|sgd:S000001856|dip:DIP-2019N|mint:P01123|ensemblfungi:YFL038C(gene)|ensemblfungi:YFL038C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0061709"(reticulophagy)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1990261"(pre-mRNA catabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1UKV|rcsb pdb:1YZN|rcsb pdb:2BCG|rcsb pdb:3CUE|rcsb pdb:7KMT|reactome:R-SCE-162658|reactome:R-SCE-204005|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-8873719|reactome:R-SCE-8876198 psi-mi:"MI:0469"(intact) - crc64:F8C704F6BF2D227B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dP6LgGWZ+WfVhk9QDo9hnv/eOMs559292 rogid:IMz/iERXs1zvX+wgJ9x7Uk0ovQ8559292 intact-crc:4C38D0706ECA245D|rigid:zCmhkZ8olZmt2vJ7gjquf8QzkQM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01123 uniprotkb:P54783 intact:EBI-29496|uniprotkb:D6VTJ2|ensemblfungi:YFL038C intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:ypt1_yeast(display_long)|uniprotkb:YFL038C(locus name)|uniprotkb:YPT1(gene name)|psi-mi:YPT1(display_short)|uniprotkb:YP2(gene name synonym)|uniprotkb:Rab GTPase YPT1(gene name synonym)|uniprotkb:Transport GTPase YPT1(gene name synonym)|uniprotkb:Protein YP2(gene name synonym) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314045|imex:IM-14275-14 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116615.1|sgd:S000001856|dip:DIP-2019N|mint:P01123|ensemblfungi:YFL038C(gene)|ensemblfungi:YFL038C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0061709"(reticulophagy)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1990261"(pre-mRNA catabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1UKV|rcsb pdb:1YZN|rcsb pdb:2BCG|rcsb pdb:3CUE|rcsb pdb:7KMT|reactome:R-SCE-162658|reactome:R-SCE-204005|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-8873719|reactome:R-SCE-8876198 go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) crc64:F8C704F6BF2D227B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IMz/iERXs1zvX+wgJ9x7Uk0ovQ8559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:D4D15BAFFBD3F2C3|rigid:QiYPvwBsu4X9f1LKrQyphdJZe1Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02309 uniprotkb:P32447 intact:EBI-8113|uniprotkb:D6VQ10|ensemblfungi:YBR009C|ensemblfungi:YNL030W intact:EBI-3003|uniprotkb:D6VW69|ensemblfungi:YJL115W psi-mi:h4_yeast(display_long)|uniprotkb:N2752(orf name)|uniprotkb:YBR0122(orf name)|uniprotkb:YBR009C(locus name)|uniprotkb:YNL030W(locus name)|uniprotkb:HHF1(gene name)|psi-mi:HHF1(display_short)|uniprotkb:HHF2(gene name)|psi-mi:HHF2(display_short) psi-mi:asf1_yeast(display_long)|uniprotkb:ASF1(gene name)|psi-mi:ASF1(display_short)|uniprotkb:YJL115W(locus name)|uniprotkb:J0755(orf name)|uniprotkb:CIA1(gene name synonym)|uniprotkb:Anti-silencing function protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314078|imex:IM-14275-17 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009563.1|refseq:NP_014368.1|sgd:S000000213|sgd:S000004975|dip:DIP-418N|mint:P02309|ensemblfungi:YBR009C(gene)|ensemblfungi:YBR009C_mRNA(transcript)|ensemblfungi:YNL030W(gene)|ensemblfungi:YNL030W_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|interpro:IPR001951(Histone H4)|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|rcsb pdb:1E6I|rcsb pdb:1ID3|rcsb pdb:1Q1A|rcsb pdb:1SZC|rcsb pdb:1SZD|rcsb pdb:2DVQ|rcsb pdb:2DVR|rcsb pdb:2E3K|rcsb pdb:2FSB|rcsb pdb:2H2H|rcsb pdb:2L5A|rcsb pdb:2QQF|rcsb pdb:2QQG|rcsb pdb:3TO6|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:4TWI|rcsb pdb:4TWJ|rcsb pdb:5W0V|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6QLD|rcsb pdb:6RXJ|rcsb pdb:6RXK|rcsb pdb:6RXL|rcsb pdb:6RXM|rcsb pdb:6RXO|rcsb pdb:6RXP|rcsb pdb:6RXQ|rcsb pdb:6RXR|rcsb pdb:7K78|rcsb pdb:7K7G|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-3214842|reactome:R-SCE-3214847|reactome:R-SCE-3214858|reactome:R-SCE-4551638|reactome:R-SCE-9018519 refseq:NP_012420.1|sgd:S000003651|dip:DIP-2675N|mint:P32447|ensemblfungi:YJL115W(gene)|ensemblfungi:YJL115W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006348"|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0043486"(histone exchange)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0070775"(H3 histone acetyltransferase complex)|go:"GO:0097043"(histone H3-K56 acetylation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR017282(Histone deposition protein Asf1)|interpro:IPR036747|rcsb pdb:1ROC|rcsb pdb:1WG3|rcsb pdb:2HUE|rcsb pdb:2IDC|rcsb pdb:2YGV|rcsb pdb:4EO5|rcsb pdb:4ZBJ|rcsb pdb:5EII|rcsb pdb:5UCB|rcsb pdb:5UEA|rcsb pdb:5UEK|rcsb pdb:6AYZ|rcsb pdb:6AZ2|rcsb pdb:6F0Y|rcsb pdb:6O22|reactome:R-SCE-2559584 psi-mi:"MI:0469"(intact) crc64:69B7D1F89E62DE41 crc64:186E76075C0B1644 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wGtUrumyxGKsW9BEzkBW3FwvwUo559292 rogid:En27z1xiUMZBu18Nq9rrAsUy5Zs559292 intact-crc:CEB82C2017300E9F|rigid:D56CAPqyTo02dC3aqiBP8/3Tmm0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02309 uniprotkb:P02309 intact:EBI-8113|uniprotkb:D6VQ10|ensemblfungi:YBR009C|ensemblfungi:YNL030W intact:EBI-8113|uniprotkb:D6VQ10|ensemblfungi:YBR009C|ensemblfungi:YNL030W psi-mi:h4_yeast(display_long)|uniprotkb:N2752(orf name)|uniprotkb:YBR0122(orf name)|uniprotkb:YBR009C(locus name)|uniprotkb:YNL030W(locus name)|uniprotkb:HHF1(gene name)|psi-mi:HHF1(display_short)|uniprotkb:HHF2(gene name)|psi-mi:HHF2(display_short) psi-mi:h4_yeast(display_long)|uniprotkb:N2752(orf name)|uniprotkb:YBR0122(orf name)|uniprotkb:YBR009C(locus name)|uniprotkb:YNL030W(locus name)|uniprotkb:HHF1(gene name)|psi-mi:HHF1(display_short)|uniprotkb:HHF2(gene name)|psi-mi:HHF2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314067|imex:IM-14275-16 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009563.1|refseq:NP_014368.1|sgd:S000000213|sgd:S000004975|dip:DIP-418N|mint:P02309|ensemblfungi:YBR009C(gene)|ensemblfungi:YBR009C_mRNA(transcript)|ensemblfungi:YNL030W(gene)|ensemblfungi:YNL030W_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|interpro:IPR001951(Histone H4)|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|rcsb pdb:1E6I|rcsb pdb:1ID3|rcsb pdb:1Q1A|rcsb pdb:1SZC|rcsb pdb:1SZD|rcsb pdb:2DVQ|rcsb pdb:2DVR|rcsb pdb:2E3K|rcsb pdb:2FSB|rcsb pdb:2H2H|rcsb pdb:2L5A|rcsb pdb:2QQF|rcsb pdb:2QQG|rcsb pdb:3TO6|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:4TWI|rcsb pdb:4TWJ|rcsb pdb:5W0V|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6QLD|rcsb pdb:6RXJ|rcsb pdb:6RXK|rcsb pdb:6RXL|rcsb pdb:6RXM|rcsb pdb:6RXO|rcsb pdb:6RXP|rcsb pdb:6RXQ|rcsb pdb:6RXR|rcsb pdb:7K78|rcsb pdb:7K7G|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-3214842|reactome:R-SCE-3214847|reactome:R-SCE-3214858|reactome:R-SCE-4551638|reactome:R-SCE-9018519 refseq:NP_009563.1|refseq:NP_014368.1|sgd:S000000213|sgd:S000004975|dip:DIP-418N|mint:P02309|ensemblfungi:YBR009C(gene)|ensemblfungi:YBR009C_mRNA(transcript)|ensemblfungi:YNL030W(gene)|ensemblfungi:YNL030W_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|interpro:IPR001951(Histone H4)|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|rcsb pdb:1E6I|rcsb pdb:1ID3|rcsb pdb:1Q1A|rcsb pdb:1SZC|rcsb pdb:1SZD|rcsb pdb:2DVQ|rcsb pdb:2DVR|rcsb pdb:2E3K|rcsb pdb:2FSB|rcsb pdb:2H2H|rcsb pdb:2L5A|rcsb pdb:2QQF|rcsb pdb:2QQG|rcsb pdb:3TO6|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:4TWI|rcsb pdb:4TWJ|rcsb pdb:5W0V|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6QLD|rcsb pdb:6RXJ|rcsb pdb:6RXK|rcsb pdb:6RXL|rcsb pdb:6RXM|rcsb pdb:6RXO|rcsb pdb:6RXP|rcsb pdb:6RXQ|rcsb pdb:6RXR|rcsb pdb:7K78|rcsb pdb:7K7G|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-3214842|reactome:R-SCE-3214847|reactome:R-SCE-3214858|reactome:R-SCE-4551638|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) crc64:69B7D1F89E62DE41 crc64:69B7D1F89E62DE41 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wGtUrumyxGKsW9BEzkBW3FwvwUo559292 rogid:wGtUrumyxGKsW9BEzkBW3FwvwUo559292 intact-crc:E91EF435AD050C1C|rigid:nHQJqGmYAsLO7POFLazk+iXATt8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61830 uniprotkb:P02309 intact:EBI-8098|uniprotkb:E9PAG1|uniprotkb:P02303|uniprotkb:P13996|uniprotkb:Q6B1U3|uniprotkb:Q6Q7G9|uniprotkb:D6VQ11|ensemblfungi:YBR010W|ensemblfungi:YNL031C intact:EBI-8113|uniprotkb:D6VQ10|ensemblfungi:YBR009C|ensemblfungi:YNL030W psi-mi:h3_yeast(display_long)|uniprotkb:SIN2(gene name synonym)|uniprotkb:YNL031C(locus name)|uniprotkb:N2749(orf name)|uniprotkb:HHT1(gene name)|psi-mi:HHT1(display_short)|uniprotkb:YBR010W(locus name)|uniprotkb:YBR0201(orf name)|uniprotkb:HHT2(gene name)|psi-mi:HHT2(display_short) psi-mi:h4_yeast(display_long)|uniprotkb:N2752(orf name)|uniprotkb:YBR0122(orf name)|uniprotkb:YBR009C(locus name)|uniprotkb:YNL030W(locus name)|uniprotkb:HHF1(gene name)|psi-mi:HHF1(display_short)|uniprotkb:HHF2(gene name)|psi-mi:HHF2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314089|imex:IM-14275-18 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009564.1|refseq:NP_014367.1|sgd:S000000214|sgd:S000004976|mint:P61830|dip:DIP-417N|ensemblfungi:YBR010W(gene)|ensemblfungi:YBR010W_mRNA(transcript)|ensemblfungi:YNL031C(gene)|ensemblfungi:YNL031C_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:1ID3|rcsb pdb:1M1D|rcsb pdb:1PEG|rcsb pdb:1PU9|rcsb pdb:1PUA|rcsb pdb:1QSN|rcsb pdb:2CNX|rcsb pdb:2H2G|rcsb pdb:2IDC|rcsb pdb:2JMJ|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:2RSN|rcsb pdb:3MP1|rcsb pdb:3MP6|rcsb pdb:3Q33|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6J2P|rcsb pdb:6KMJ|rcsb pdb:7K7G refseq:NP_009563.1|refseq:NP_014368.1|sgd:S000000213|sgd:S000004975|dip:DIP-418N|mint:P02309|ensemblfungi:YBR009C(gene)|ensemblfungi:YBR009C_mRNA(transcript)|ensemblfungi:YNL030W(gene)|ensemblfungi:YNL030W_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|interpro:IPR001951(Histone H4)|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|rcsb pdb:1E6I|rcsb pdb:1ID3|rcsb pdb:1Q1A|rcsb pdb:1SZC|rcsb pdb:1SZD|rcsb pdb:2DVQ|rcsb pdb:2DVR|rcsb pdb:2E3K|rcsb pdb:2FSB|rcsb pdb:2H2H|rcsb pdb:2L5A|rcsb pdb:2QQF|rcsb pdb:2QQG|rcsb pdb:3TO6|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:4TWI|rcsb pdb:4TWJ|rcsb pdb:5W0V|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6QLD|rcsb pdb:6RXJ|rcsb pdb:6RXK|rcsb pdb:6RXL|rcsb pdb:6RXM|rcsb pdb:6RXO|rcsb pdb:6RXP|rcsb pdb:6RXQ|rcsb pdb:6RXR|rcsb pdb:7K78|rcsb pdb:7K7G|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-3214842|reactome:R-SCE-3214847|reactome:R-SCE-3214858|reactome:R-SCE-4551638|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) crc64:A6115FEB480AC67A crc64:69B7D1F89E62DE41 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jtDVNjrs2tJMmr/dqrvnNiQ2ppQ559292 rogid:wGtUrumyxGKsW9BEzkBW3FwvwUo559292 intact-crc:A756003B83EDAD09|rigid:MBBZpF6i3n5Gw+ZjhZ0xSmuMkJI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06205 uniprotkb:P02309 intact:EBI-6956|uniprotkb:D6VZ83|ensemblfungi:YLR449W intact:EBI-8113|uniprotkb:D6VQ10|ensemblfungi:YBR009C|ensemblfungi:YNL030W psi-mi:fkbp4_yeast(display_long)|uniprotkb:FPR4(gene name)|psi-mi:FPR4(display_short)|uniprotkb:YLR449W(locus name)|uniprotkb:L9324.3(orf name)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Histone proline isomerase(gene name synonym) psi-mi:h4_yeast(display_long)|uniprotkb:N2752(orf name)|uniprotkb:YBR0122(orf name)|uniprotkb:YBR009C(locus name)|uniprotkb:YNL030W(locus name)|uniprotkb:HHF1(gene name)|psi-mi:HHF1(display_short)|uniprotkb:HHF2(gene name)|psi-mi:HHF2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314100|imex:IM-14275-19 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004441|refseq:NP_013554.3|dip:DIP-909N|mint:Q06205|ensemblfungi:YLR449W(gene)|ensemblfungi:YLR449W_mRNA(transcript)|go:"GO:0000412"(histone peptidyl-prolyl isomerization)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR023566|interpro:IPR041232|rcsb pdb:4BF8 refseq:NP_009563.1|refseq:NP_014368.1|sgd:S000000213|sgd:S000004975|dip:DIP-418N|mint:P02309|ensemblfungi:YBR009C(gene)|ensemblfungi:YBR009C_mRNA(transcript)|ensemblfungi:YNL030W(gene)|ensemblfungi:YNL030W_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|interpro:IPR001951(Histone H4)|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|rcsb pdb:1E6I|rcsb pdb:1ID3|rcsb pdb:1Q1A|rcsb pdb:1SZC|rcsb pdb:1SZD|rcsb pdb:2DVQ|rcsb pdb:2DVR|rcsb pdb:2E3K|rcsb pdb:2FSB|rcsb pdb:2H2H|rcsb pdb:2L5A|rcsb pdb:2QQF|rcsb pdb:2QQG|rcsb pdb:3TO6|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:4TWI|rcsb pdb:4TWJ|rcsb pdb:5W0V|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6QLD|rcsb pdb:6RXJ|rcsb pdb:6RXK|rcsb pdb:6RXL|rcsb pdb:6RXM|rcsb pdb:6RXO|rcsb pdb:6RXP|rcsb pdb:6RXQ|rcsb pdb:6RXR|rcsb pdb:7K78|rcsb pdb:7K7G|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-3214842|reactome:R-SCE-3214847|reactome:R-SCE-3214858|reactome:R-SCE-4551638|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) crc64:CF90C6714F04572E crc64:69B7D1F89E62DE41 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rDmDSGEgRbtgkLBoJTzmzxxY7B4559292 rogid:wGtUrumyxGKsW9BEzkBW3FwvwUo559292 intact-crc:480F74E4AB238380|rigid:n3VooWclUU9xxQj8cMXyCQTWqq4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07286 uniprotkb:P04046 intact:EBI-7852|uniprotkb:D6VQN9|ensemblfungi:YBR243C intact:EBI-14238|ensemblfungi:YMR300C|uniprotkb:D6W0C7 psi-mi:gpt_yeast(display_long)|uniprotkb:TUR1(gene name synonym)|uniprotkb:YBR1628(orf name)|uniprotkb:YBR243C(locus name)|uniprotkb:ALG7(gene name)|psi-mi:ALG7(display_short)|uniprotkb:N-acetylglucosamine-1-phosphate transferase(gene name synonym)|uniprotkb:GlcNAc-1-P transferase(gene name synonym)|uniprotkb:Tunicamycin resistance protein 1(gene name synonym) psi-mi:pur1_yeast(display_long)|uniprotkb:Glutamine phosphoribosylpyrophosphate amidotransferase(gene name synonym)|uniprotkb:ADE4(gene name)|psi-mi:ADE4(display_short)|uniprotkb:YMR300C(locus name)|uniprotkb:YM9952.02C(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314133|imex:IM-14275-22 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000447|refseq:NP_009802.3|dip:DIP-5364N|mint:P07286|ensemblfungi:YBR243C(gene)|ensemblfungi:YBR243C_mRNA(transcript)|go:"GO:0003975"(UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006489"(dolichyl diphosphate biosynthetic process)|go:"GO:0008963"(phospho-N-acetylmuramoyl-pentapeptide-transferase activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0043541"(UDP-N-acetylglucosamine transferase complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR000715(Glycosyl transferase, family 4)|interpro:IPR033895|reactome:R-SCE-446193 refseq:NP_014029.1|sgd:S000004915|ensemblfungi:YMR300C(gene)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005854(Amidophosphoribosyl transferase)|ensemblfungi:YMR300C_mRNA(transcript)|go:"GO:0004044"(amidophosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR017932|interpro:IPR029055|interpro:IPR029057|interpro:IPR035584|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|mint:P04046|dip:DIP-6727N psi-mi:"MI:0469"(intact) - crc64:1FE7A6F5B7C96710 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nwAb0WMTgVU4LoAGHFxOjCYe1ok559292 rogid:v3Q2NjIC4OuMxGAFnC+1r4y70mw559292 intact-crc:E3A4DF4BD71C6D1B|rigid:967GTg09kXHFMsPqbp6yUoJ9sXY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04046 uniprotkb:P04046 intact:EBI-14238|ensemblfungi:YMR300C|uniprotkb:D6W0C7 intact:EBI-14238|ensemblfungi:YMR300C|uniprotkb:D6W0C7 psi-mi:pur1_yeast(display_long)|uniprotkb:Glutamine phosphoribosylpyrophosphate amidotransferase(gene name synonym)|uniprotkb:ADE4(gene name)|psi-mi:ADE4(display_short)|uniprotkb:YMR300C(locus name)|uniprotkb:YM9952.02C(orf name) psi-mi:pur1_yeast(display_long)|uniprotkb:Glutamine phosphoribosylpyrophosphate amidotransferase(gene name synonym)|uniprotkb:ADE4(gene name)|psi-mi:ADE4(display_short)|uniprotkb:YMR300C(locus name)|uniprotkb:YM9952.02C(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314122|imex:IM-14275-21 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014029.1|sgd:S000004915|ensemblfungi:YMR300C(gene)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005854(Amidophosphoribosyl transferase)|ensemblfungi:YMR300C_mRNA(transcript)|go:"GO:0004044"(amidophosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR017932|interpro:IPR029055|interpro:IPR029057|interpro:IPR035584|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|mint:P04046|dip:DIP-6727N refseq:NP_014029.1|sgd:S000004915|ensemblfungi:YMR300C(gene)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005854(Amidophosphoribosyl transferase)|ensemblfungi:YMR300C_mRNA(transcript)|go:"GO:0004044"(amidophosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR017932|interpro:IPR029055|interpro:IPR029057|interpro:IPR035584|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|mint:P04046|dip:DIP-6727N psi-mi:"MI:0469"(intact) crc64:1FE7A6F5B7C96710 crc64:1FE7A6F5B7C96710 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:v3Q2NjIC4OuMxGAFnC+1r4y70mw559292 rogid:v3Q2NjIC4OuMxGAFnC+1r4y70mw559292 intact-crc:9244BFACA3F53F16|rigid:1cxsfQCFtGdhjNFMfLCT7Lsuyjg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12373 uniprotkb:P02309 intact:EBI-31911|uniprotkb:D6VXY2|ensemblfungi:YLL022C intact:EBI-8113|uniprotkb:D6VQ10|ensemblfungi:YBR009C|ensemblfungi:YNL030W psi-mi:hif1_yeast(display_long)|uniprotkb:HIF1(gene name)|psi-mi:HIF1(display_short)|uniprotkb:L1205(orf name)|uniprotkb:YLL022C(locus name) psi-mi:h4_yeast(display_long)|uniprotkb:N2752(orf name)|uniprotkb:YBR0122(orf name)|uniprotkb:YBR009C(locus name)|uniprotkb:YNL030W(locus name)|uniprotkb:HHF1(gene name)|psi-mi:HHF1(display_short)|uniprotkb:HHF2(gene name)|psi-mi:HHF2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314111|imex:IM-14275-20 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013078.1|sgd:S000003945|dip:DIP-6442N|mint:Q12373|ensemblfungi:YLL022C(gene)|ensemblfungi:YLL022C_mRNA(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006348"|go:"GO:0016573"(histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:4NQ0|rcsb pdb:5BT1 refseq:NP_009563.1|refseq:NP_014368.1|sgd:S000000213|sgd:S000004975|dip:DIP-418N|mint:P02309|ensemblfungi:YBR009C(gene)|ensemblfungi:YBR009C_mRNA(transcript)|ensemblfungi:YNL030W(gene)|ensemblfungi:YNL030W_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|interpro:IPR001951(Histone H4)|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|rcsb pdb:1E6I|rcsb pdb:1ID3|rcsb pdb:1Q1A|rcsb pdb:1SZC|rcsb pdb:1SZD|rcsb pdb:2DVQ|rcsb pdb:2DVR|rcsb pdb:2E3K|rcsb pdb:2FSB|rcsb pdb:2H2H|rcsb pdb:2L5A|rcsb pdb:2QQF|rcsb pdb:2QQG|rcsb pdb:3TO6|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:4TWI|rcsb pdb:4TWJ|rcsb pdb:5W0V|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6QLD|rcsb pdb:6RXJ|rcsb pdb:6RXK|rcsb pdb:6RXL|rcsb pdb:6RXM|rcsb pdb:6RXO|rcsb pdb:6RXP|rcsb pdb:6RXQ|rcsb pdb:6RXR|rcsb pdb:7K78|rcsb pdb:7K7G|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-3214842|reactome:R-SCE-3214847|reactome:R-SCE-3214858|reactome:R-SCE-4551638|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) crc64:B280CFCCB6896506 crc64:69B7D1F89E62DE41 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4bOpAXdlDl6LtBQ+BjueT5/24aA559292 rogid:wGtUrumyxGKsW9BEzkBW3FwvwUo559292 intact-crc:6F44C49735503DA4|rigid:J2cl/7HicfJzxEJDzbxSMrQdkAI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54783 uniprotkb:P04046 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 intact:EBI-14238|ensemblfungi:YMR300C|uniprotkb:D6W0C7 psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:pur1_yeast(display_long)|uniprotkb:Glutamine phosphoribosylpyrophosphate amidotransferase(gene name synonym)|uniprotkb:ADE4(gene name)|psi-mi:ADE4(display_short)|uniprotkb:YMR300C(locus name)|uniprotkb:YM9952.02C(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314144|imex:IM-14275-23 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 refseq:NP_014029.1|sgd:S000004915|ensemblfungi:YMR300C(gene)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005854(Amidophosphoribosyl transferase)|ensemblfungi:YMR300C_mRNA(transcript)|go:"GO:0004044"(amidophosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR017932|interpro:IPR029055|interpro:IPR029057|interpro:IPR035584|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|mint:P04046|dip:DIP-6727N psi-mi:"MI:0469"(intact) - crc64:1FE7A6F5B7C96710 figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 rogid:v3Q2NjIC4OuMxGAFnC+1r4y70mw559292 intact-crc:067BAF2CA0E7B5E9|rigid:oxMT+PgsEukCSIdAq+XQXiJnUBA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04387 uniprotkb:P04387 intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name) psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314155|imex:IM-14275-24 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U psi-mi:"MI:0469"(intact) crc64:1492473684F3894C crc64:1492473684F3894C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292 rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292 intact-crc:E730DB30B8B909BE|rigid:dw/fJV+mYmhiU3b4EPAi5Wr46LE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32450 uniprotkb:P05085 intact:EBI-2045077|uniprotkb:D6VTL9|ensemblfungi:YFL010W-A intact:EBI-2835|uniprotkb:D6W0I6|ensemblfungi:YML099C psi-mi:aua1_yeast(display_long)|uniprotkb:YFL010BW(orf name)|uniprotkb:YFL010W-A(locus name)|uniprotkb:AUA1(gene name)|psi-mi:AUA1(display_short) psi-mi:argr2_yeast(display_long)|uniprotkb:ARG81(gene name)|psi-mi:ARG81(display_short)|uniprotkb:Arginine-requiring protein 81(gene name synonym)|uniprotkb:ARGR2(gene name synonym)|uniprotkb:YML099C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314166|imex:IM-14275-25 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001955|refseq:NP_116645.1|dip:DIP-5756N|mint:P32450|ensemblfungi:YFL010W-A(gene)|ensemblfungi:YFL010W-A_mRNA(transcript)|go:"GO:0006865"(amino acid transport) refseq:NP_013610.1|sgd:S000004565|dip:DIP-1346N|mint:P05085|ensemblfungi:YML099C(gene)|ensemblfungi:YML099C_mRNA(transcript)|go:"GO:0000821"(regulation of arginine metabolic process)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006525"(arginine metabolic process)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR021858|interpro:IPR036864 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3L8RSm2gZy02CkNAhIvggshZDkY559292 rogid:ZdPDhdO2yHCzuFNPDvCpmv4BBKI559292 intact-crc:A4083919F314D60D|rigid:QuVIbEZ1s3xKpDASkL5AH31u0yg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P05373 uniprotkb:P05373 intact:EBI-8239|uniprotkb:D6VU99|ensemblfungi:YGL040C intact:EBI-8239|uniprotkb:D6VU99|ensemblfungi:YGL040C psi-mi:hem2_yeast(display_long)|uniprotkb:YGL040C(locus name)|uniprotkb:HEM2(gene name)|psi-mi:HEM2(display_short)|uniprotkb:Porphobilinogen synthase(gene name synonym) psi-mi:hem2_yeast(display_long)|uniprotkb:YGL040C(locus name)|uniprotkb:HEM2(gene name)|psi-mi:HEM2(display_short)|uniprotkb:Porphobilinogen synthase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314177|imex:IM-14275-26 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011475.1|sgd:S000003008|dip:DIP-4311N|mint:P05373|ensemblfungi:YGL040C(gene)|ensemblfungi:YGL040C_mRNA(transcript)|go:"GO:0004655"(porphobilinogen synthase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001731(Tetrapyrrole biosynthesis, porphobilinogen synthase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR030656|rcsb pdb:1AW5|rcsb pdb:1EB3|rcsb pdb:1GJP|rcsb pdb:1H7N|rcsb pdb:1H7O|rcsb pdb:1H7P|rcsb pdb:1H7R|rcsb pdb:1OHL|rcsb pdb:1QML|rcsb pdb:1QNV|rcsb pdb:1W31|rcsb pdb:1YLV|reactome:R-SCE-189451|reactome:R-SCE-6798695 refseq:NP_011475.1|sgd:S000003008|dip:DIP-4311N|mint:P05373|ensemblfungi:YGL040C(gene)|ensemblfungi:YGL040C_mRNA(transcript)|go:"GO:0004655"(porphobilinogen synthase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001731(Tetrapyrrole biosynthesis, porphobilinogen synthase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR030656|rcsb pdb:1AW5|rcsb pdb:1EB3|rcsb pdb:1GJP|rcsb pdb:1H7N|rcsb pdb:1H7O|rcsb pdb:1H7P|rcsb pdb:1H7R|rcsb pdb:1OHL|rcsb pdb:1QML|rcsb pdb:1QNV|rcsb pdb:1W31|rcsb pdb:1YLV|reactome:R-SCE-189451|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:S4alH7/4/Jm8aopWiVPjQaakAow559292 rogid:S4alH7/4/Jm8aopWiVPjQaakAow559292 intact-crc:34D9AEEC9A8AFC1F|rigid:6Wi+SBzPGniyORsoUhv25irt/jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P05374 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-2049142|uniprotkb:D6VUT7|ensemblfungi:YGR157W psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:cho2_yeast(display_long)|uniprotkb:CHO2(gene name)|psi-mi:CHO2(display_short)|uniprotkb:G6673(orf name)|uniprotkb:YGR157W(locus name)|uniprotkb:PEM1(gene name synonym)|uniprotkb:Choline-requiring protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314188|imex:IM-14275-27 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_011673.1|sgd:S000003389|dip:DIP-8037N|mint:P05374|ensemblfungi:YGR157W(gene)|ensemblfungi:YGR157W_mRNA(transcript)|go:"GO:0004608"(phosphatidylethanolamine N-methyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032259"(methylation)|go:"GO:0071944"(cell periphery)|interpro:IPR007318(Phospholipid methyltransferase)|interpro:IPR016219(Phosphatidylethanolamine N-methyltransferase, fungi) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:YWaukyppUNK723TemdAUWmvvrbY559292 intact-crc:288E8316A0D7900B|rigid:qvK5fezZRPTG6oSAHMBenKVJ5+U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06100 uniprotkb:P06102 intact:EBI-12153|uniprotkb:D6VRI6|ensemblfungi:YDL165W intact:EBI-12165|uniprotkb:D6VVP4|uniprotkb:Q6B233|ensemblfungi:YIL038C psi-mi:not2_yeast(display_long)|uniprotkb:CDC36(gene name)|psi-mi:CDC36(display_short)|uniprotkb:DNA19(gene name synonym)|uniprotkb:NOT2(gene name synonym)|uniprotkb:YDL165W(locus name)|uniprotkb:cell division cycle protein 36(gene name synonym) psi-mi:not3_yeast(display_long)|uniprotkb:NOT3(gene name)|psi-mi:NOT3(display_short)|uniprotkb:YIL038C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314199|imex:IM-14275-28 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDL165W(gene)|ensemblfungi:YDL165W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|refseq:NP_010116.1|sgd:S000002324|dip:DIP-590N|mint:P06100 interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR038635|interpro:IPR040168|ensemblfungi:YIL038C(gene)|ensemblfungi:YIL038C_mRNA(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|refseq:NP_012226.3|sgd:S000001300|dip:DIP-2256N|mint:P06102 psi-mi:"MI:0469"(intact) crc64:7D0B69657F791371 crc64:69B76694FCC6846F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:bOgpnRcqWbxkhHJg140qzPxIBJQ559292 rogid:EfakZPDNU3FZeI5+rnu7YV1UsCg559292 intact-crc:E76735C74867FD6D|rigid:USbCfCMFd2MmrUfjA/9d+lD6oyY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25644 uniprotkb:P06100 intact:EBI-204|uniprotkb:Q8NKJ3|uniprotkb:D6VR80|ensemblfungi:YCR077C intact:EBI-12153|uniprotkb:D6VRI6|ensemblfungi:YDL165W psi-mi:pat1_yeast(display_long)|uniprotkb:PAT1(gene name)|psi-mi:PAT1(display_short)|uniprotkb:Decapping activator and translational repressor PAT1(gene name synonym)|uniprotkb:mRNA turnover protein 1(gene name synonym)|uniprotkb:MRT1(gene name synonym)|uniprotkb:Topoisomerase II-associated protein PAT1(gene name synonym)|uniprotkb:YCR77C(orf name)|uniprotkb:YCR077C(locus name) psi-mi:not2_yeast(display_long)|uniprotkb:CDC36(gene name)|psi-mi:CDC36(display_short)|uniprotkb:DNA19(gene name synonym)|uniprotkb:NOT2(gene name synonym)|uniprotkb:YDL165W(locus name)|uniprotkb:cell division cycle protein 36(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314210|imex:IM-14275-29 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010002.3|sgd:S000000673|mint:P25644|dip:DIP-883N|ensemblfungi:YCR077C(gene)|ensemblfungi:YCR077C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000776"(kinetochore)|go:"GO:0000932"(P-body)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033962"(P-body assembly)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0051301"(cell division)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR019167|interpro:IPR039900|rcsb pdb:4BRW|rcsb pdb:4C8Q|rcsb pdb:4N0A|rcsb pdb:4OGP|rcsb pdb:4OJJ|rcsb pdb:5LM5|rcsb pdb:5LMF|rcsb pdb:5LMG|reactome:R-SCE-430039 ensemblfungi:YDL165W(gene)|ensemblfungi:YDL165W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|refseq:NP_010116.1|sgd:S000002324|dip:DIP-590N|mint:P06100 psi-mi:"MI:0469"(intact) crc64:2DBE1210C173E468 crc64:7D0B69657F791371 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kov8R0RAgIOPffQ7ydjCUxjoE/M559292 rogid:bOgpnRcqWbxkhHJg140qzPxIBJQ559292 intact-crc:0C27F85249546C01|rigid:1acfLKbvMmrAV6Tk0M0KQutFlJM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25655 uniprotkb:P06100 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-12153|uniprotkb:D6VRI6|ensemblfungi:YDL165W psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:not2_yeast(display_long)|uniprotkb:CDC36(gene name)|psi-mi:CDC36(display_short)|uniprotkb:DNA19(gene name synonym)|uniprotkb:NOT2(gene name synonym)|uniprotkb:YDL165W(locus name)|uniprotkb:cell division cycle protein 36(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314221|imex:IM-14275-30 author score:99.34 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 ensemblfungi:YDL165W(gene)|ensemblfungi:YDL165W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|refseq:NP_010116.1|sgd:S000002324|dip:DIP-590N|mint:P06100 psi-mi:"MI:0469"(intact) crc64:5B2AE15BCF95E009 crc64:7D0B69657F791371 figure legend:tables S3 and S4|author-confidence:99.34|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:bOgpnRcqWbxkhHJg140qzPxIBJQ559292 intact-crc:E2C788AF4A85C60B|rigid:pG+dlnqcr7S2lPdwvUlQbxVpjLk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06100 uniprotkb:P34909 intact:EBI-12153|uniprotkb:D6VRI6|ensemblfungi:YDL165W intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W psi-mi:not2_yeast(display_long)|uniprotkb:CDC36(gene name)|psi-mi:CDC36(display_short)|uniprotkb:DNA19(gene name synonym)|uniprotkb:NOT2(gene name synonym)|uniprotkb:YDL165W(locus name)|uniprotkb:cell division cycle protein 36(gene name synonym) psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314232|imex:IM-14275-31 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDL165W(gene)|ensemblfungi:YDL165W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|refseq:NP_010116.1|sgd:S000002324|dip:DIP-590N|mint:P06100 ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 psi-mi:"MI:0469"(intact) crc64:7D0B69657F791371 crc64:8847084BD9BF48B7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:bOgpnRcqWbxkhHJg140qzPxIBJQ559292 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 intact-crc:5DA0EF18C23593B4|rigid:JXfMD3TC8vGlh/nXKH+Sk9jskmI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53829 uniprotkb:P06100 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-12153|uniprotkb:D6VRI6|ensemblfungi:YDL165W psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:not2_yeast(display_long)|uniprotkb:CDC36(gene name)|psi-mi:CDC36(display_short)|uniprotkb:DNA19(gene name synonym)|uniprotkb:NOT2(gene name synonym)|uniprotkb:YDL165W(locus name)|uniprotkb:cell division cycle protein 36(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314243|imex:IM-14275-32 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 ensemblfungi:YDL165W(gene)|ensemblfungi:YDL165W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|refseq:NP_010116.1|sgd:S000002324|dip:DIP-590N|mint:P06100 psi-mi:"MI:0469"(intact) crc64:F3DBABE6AD3C7F3C crc64:7D0B69657F791371 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:bOgpnRcqWbxkhHJg140qzPxIBJQ559292 intact-crc:DA13F7CE6BFF96D1|rigid:KlEW0Sst2QnAGXW+pD1ViSJwKCs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06197 uniprotkb:P06197 intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314254|imex:IM-14275-33 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 psi-mi:"MI:0469"(intact) crc64:6E2E62252B3CB5E2 crc64:6E2E62252B3CB5E2 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 intact-crc:3EF16334FE72F052|rigid:7cL4ewYfGjSg1KKFtNOOIzjeztI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06197 uniprotkb:P35196 intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W intact:EBI-14943|uniprotkb:D6VQ03|ensemblfungi:YBR002C psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:rer2_yeast(display_long)|uniprotkb:"Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific)"(gene name synonym)|uniprotkb:YBR0107(orf name)|uniprotkb:RER2(gene name)|psi-mi:RER2(display_short)|uniprotkb:YBR002C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314309|imex:IM-14275-38 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 interpro:IPR036424|refseq:NP_009556.1|sgd:S000000206|interpro:IPR001441(Di-trans-poly-cis-decaprenylcistransferase)|interpro:IPR018520|ensemblfungi:YBR002C(gene)|ensemblfungi:YBR002C_mRNA(transcript)|go:"GO:0002094"(polyprenyltransferase activity)|go:"GO:0004659"(prenyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016094"(polyprenol biosynthetic process)|go:"GO:0019408"(dolichol biosynthetic process)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0045547"(dehydrodolichyl diphosphate synthase activity)|go:"GO:1904423"(dehydrodolichyl diphosphate synthase complex)|reactome:R-SCE-446199|mint:P35196 psi-mi:"MI:0469"(intact) crc64:6E2E62252B3CB5E2 - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 rogid:gVl9E/6GKqKsUp/5VLdT5XGbjUM559292 intact-crc:E3B95FA1F870D902|rigid:Tm+0koK9jTcBEhr7U0gTI84CRWw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06197 uniprotkb:P10614 intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314265|imex:IM-14275-34 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) crc64:6E2E62252B3CB5E2 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:181D70B85930966A|rigid:dCiRI521kSt/jje/XwMI+BZNqk8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16603 uniprotkb:P06197 intact:EBI-11940|ensemblfungi:YHR042W|uniprotkb:D3DKZ0 intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W psi-mi:ncpr_yeast(display_long)|uniprotkb:NCP1(gene name)|psi-mi:NCP1(display_short)|uniprotkb:NCPR1(gene name synonym)|uniprotkb:PRD1(gene name synonym)|uniprotkb:CPR1(gene name synonym)|uniprotkb:YHR042W(locus name) psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314276|imex:IM-14275-35 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR042W(gene)|ensemblfungi:YHR042W_mRNA(transcript)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0003959"(NADPH dehydrogenase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0010181"(FMN binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0005739"(mitochondrion)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR023208|interpro:IPR039261|rcsb pdb:2BF4|rcsb pdb:2BN4|rcsb pdb:2BPO|rcsb pdb:3FJO|reactome:R-SCE-1222556|reactome:R-SCE-1474151|reactome:R-SCE-203615|reactome:R-SCE-392154|reactome:R-SCE-5218920|reactome:R-SCE-5578775|reactome:R-SCE-9009391|reactome:R-SCE-9033241|interpro:IPR029039|refseq:NP_011908.1|sgd:S000001084|mint:P16603|dip:DIP-8294N refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 psi-mi:"MI:0469"(intact) - crc64:6E2E62252B3CB5E2 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:l8faixht4sd0KQhbt2DadH/8BPw559292 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 intact-crc:F6EE1F8010E22D46|rigid:WxJRdqayQTvk9UjN3mAr+Jpsod0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06197 uniprotkb:P26570 intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314287|imex:IM-14275-36 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N psi-mi:"MI:0469"(intact) crc64:6E2E62252B3CB5E2 crc64:8B7F009521F72C15 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 intact-crc:D3780CE371A67156|rigid:wjSy84HjyPchqEDTaPlxTvUCXB4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06197 uniprotkb:P32500 intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W intact:EBI-11950|ensemblfungi:YML031W|uniprotkb:D6VZE3 psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:ndc1_yeast(display_long)|uniprotkb:YML031W(locus name)|uniprotkb:NDC1(gene name)|psi-mi:NDC1(display_short)|uniprotkb:Nuclear pore protein NDC1(gene name synonym)|uniprotkb:Nuclear division cycle protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314298|imex:IM-14275-37 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 ensemblfungi:YML031W(gene)|ensemblfungi:YML031W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0070631"(spindle pole body localization)|go:"GO:0070762"(nuclear pore transmembrane ring)|go:"GO:0106166"(spindle pole body-nuclear membrane anchor activity)|interpro:IPR019049|go:"GO:0017056"(structural constituent of nuclear pore)|refseq:NP_013681.1|sgd:S000004493|mint:P32500|dip:DIP-1465N psi-mi:"MI:0469"(intact) crc64:6E2E62252B3CB5E2 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 rogid:CJawnqL6UYhpSqsKMbif8ifzgUY559292 intact-crc:AAF4D9FD38CA2F7C|rigid:tiA5PZ10yEIGISlsOcZ0NZsFlDc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06197 uniprotkb:P36024 intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314320|imex:IM-14275-39 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024 psi-mi:"MI:0469"(intact) crc64:6E2E62252B3CB5E2 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292 intact-crc:7A46E35020C29421|rigid:FhuT1FjXuVyYiSe5MpHNx2iooVE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38353 uniprotkb:P06197 intact:EBI-18175|uniprotkb:D6VQS8|ensemblfungi:YBR283C intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W psi-mi:ssh1_yeast(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:Ssh1 complex subunit alpha(gene name synonym)|uniprotkb:Ssh1 complex subunit SSH1(gene name synonym)|uniprotkb:YBR2020(orf name)|uniprotkb:YBR283C(locus name) psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314353|imex:IM-14275-42 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009842.1|sgd:S000000487|ensemblfungi:YBR283C(gene)|ensemblfungi:YBR283C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:2WW9|rcsb pdb:2WWA|dip:DIP-4962N|mint:P38353 refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 psi-mi:"MI:0469"(intact) crc64:48267EEA3E0191BD crc64:6E2E62252B3CB5E2 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:76wvZIdv7W5BQn6wI+sHOGQAyuc559292 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 intact-crc:6F7D706468FF49FB|rigid:hV57wfKyp3V1IaheUQnDZKaRK4Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06197 uniprotkb:P38264 intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314342|imex:IM-14275-41 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N psi-mi:"MI:0469"(intact) crc64:6E2E62252B3CB5E2 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 intact-crc:3DE3D532F07AEB43|rigid:Gz/jvyGO9YRW0sskcZjI2MTHbPI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36076 uniprotkb:P06197 intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short) psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314331|imex:IM-14275-40 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783 refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 psi-mi:"MI:0469"(intact) - crc64:6E2E62252B3CB5E2 figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Li7vZOassm4PC5fW111/j5ivgEc559292 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 intact-crc:F112DB5BD5980DAF|rigid:NJVH7tpTqmryvoNOchHuXydW4vQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40540 uniprotkb:P06197 intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314386|imex:IM-14275-45 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 psi-mi:"MI:0469"(intact) crc64:6DBEEEE7722203B0 crc64:6E2E62252B3CB5E2 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 intact-crc:C57AA3D84C6483BC|rigid:zmYd+6smuKcLhFRoj3Tvt44AVW0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54781 uniprotkb:P06197 intact:EBI-6563|uniprotkb:D6VZI9|uniprotkb:E9P965|ensemblfungi:YMR015C intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W psi-mi:erg5_yeast(display_long)|uniprotkb:ERG5(gene name)|psi-mi:ERG5(display_short)|uniprotkb:CYP61(gene name synonym)|uniprotkb:YMR015C(locus name)|uniprotkb:YM9711.02C(orf name)|uniprotkb:C-22 sterol desaturase(gene name synonym) psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314408|imex:IM-14275-47 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013728.1|sgd:S000004617|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR036396|mint:P54781|ensemblfungi:YMR015C(gene)|ensemblfungi:YMR015C_mRNA(transcript)|go:"GO:0000249"(C-22 sterol desaturase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding) refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 psi-mi:"MI:0469"(intact) - crc64:6E2E62252B3CB5E2 figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ScwspGheTequLP3AGjoNZM3cp3E559292 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 intact-crc:A4F0C47665D1763A|rigid:040mOVQYBysTMHxTbLCxJcAQqfM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02201 uniprotkb:P06197 intact:EBI-12636|uniprotkb:D6VXT9|ensemblfungi:YKR003W intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W psi-mi:osh6_yeast(display_long)|uniprotkb:YK102(orf name)|uniprotkb:YKR003W(locus name)|uniprotkb:OSH6(gene name)|psi-mi:OSH6(display_short) psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314430|imex:IM-14275-49 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0015914"(phospholipid transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0120015"(sterol transfer activity)|rcsb pdb:4B2Z|rcsb pdb:4PH7|reactome:R-SCE-1482801|reactome:R-SCE-192105|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensemblfungi:YKR003W(gene)|ensemblfungi:YKR003W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|refseq:NP_012928.1|sgd:S000001711|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|mint:Q02201 refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 psi-mi:"MI:0469"(intact) - crc64:6E2E62252B3CB5E2 figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aOZdSdLn96ns0C9w9E3r62iNyYo559292 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 intact-crc:985D16A89CE82C84|rigid:Q/m0Yg4DgQjz869nTzDpnd5vltw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06197 uniprotkb:P40471 intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W intact:EBI-25213|uniprotkb:D6VVG3|ensemblfungi:YIL124W psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:ayr1_yeast(display_long)|uniprotkb:AYR1(gene name)|psi-mi:AYR1(display_short)|uniprotkb:Acylglycerone-phosphate reductase(gene name synonym)|uniprotkb:1-acyl DHAP reductase(gene name synonym)|uniprotkb:Acyl/alkyl DHAP reductase(gene name synonym)|uniprotkb:GBG1(gene name synonym)|uniprotkb:Triacylglycerol lipase AYR1(gene name synonym)|uniprotkb:YIL124W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314375|imex:IM-14275-44 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 sgd:S000001386|refseq:NP_012142.3|mint:P40471|dip:DIP-4614N|ensemblfungi:YIL124W(gene)|ensemblfungi:YIL124W_mRNA(transcript)|go:"GO:0000140"(acylglycerone-phosphate reductase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0102566"(1-acyl dihydroxyacetone phosphate reductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291 psi-mi:"MI:0469"(intact) crc64:6E2E62252B3CB5E2 crc64:B614C0E0B1FB0CE0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 rogid:WE4RmSXARj683MNUEsYGLis36Xo559292 intact-crc:B6723C5A08D8E4FE|rigid:IrljJPaZvSb5lg+VxZqSpm/PbI4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06197 uniprotkb:P53337 intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314397|imex:IM-14275-46 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:6E2E62252B3CB5E2 - figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 intact-crc:0F00E42CE89068F8|rigid:tCzPo0b52mxy0vz9vaORYEKVa/w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38694 uniprotkb:P06197 intact:EBI-24511|uniprotkb:D3DKY6|ensemblfungi:YHR039C intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W psi-mi:msc7_yeast(display_long)|uniprotkb:MSC7(gene name)|psi-mi:MSC7(display_short)|uniprotkb:Meiotic sister-chromatid recombination protein 7(gene name synonym)|uniprotkb:YHR039C(locus name) psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314364|imex:IM-14275-43 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011904.1|sgd:S000001081|dip:DIP-1878N|mint:P38694|ensemblfungi:YHR039C(gene)|ensemblfungi:YHR039C_mRNA(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007131"(reciprocal meiotic recombination)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510 refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 psi-mi:"MI:0469"(intact) - crc64:6E2E62252B3CB5E2 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p2xtb6/xYI/jfPNtO6JRZs+5t6I559292 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 intact-crc:7CC54CBE1F3413FB|rigid:WmZbarKBEqZ/+vQ/4PWFym7EyDU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06197 uniprotkb:P54837 intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314419|imex:IM-14275-48 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:6E2E62252B3CB5E2 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:AA479BA1824ADBBF|rigid:TuUs++YX+2h0lzJNM71h9ZNdKZs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06197 uniprotkb:Q02774 intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314441|imex:IM-14275-50 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 psi-mi:"MI:0469"(intact) crc64:6E2E62252B3CB5E2 - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 intact-crc:7D8CF9BAFA3A743D|rigid:F5PTmWSVw6sJcVFAMDCMJCb1DKs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06197 uniprotkb:Q02805 intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W intact:EBI-15679|uniprotkb:D6W284|uniprotkb:Q12475|ensemblfungi:YOR018W psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:rod1_yeast(display_long)|uniprotkb:ROD1(gene name)|psi-mi:ROD1(display_short)|uniprotkb:YOR018W(locus name)|uniprotkb:OR26.08(orf name)|uniprotkb:Resistance to o-dinitrobenzene protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314452|imex:IM-14275-51 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 refseq:NP_014661.1|sgd:S000005544|ensemblfungi:YOR018W(gene)|ensemblfungi:YOR018W_mRNA(transcript)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042493"|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:0071333"(cellular response to glucose stimulus)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|dip:DIP-4189N|mint:Q02805 psi-mi:"MI:0469"(intact) crc64:6E2E62252B3CB5E2 crc64:FD9A64174B1DC443 figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 rogid:uZvRFKexlh7bpBSPflXIiLXQ910559292 intact-crc:52917E4A45F4319D|rigid:o8J/f1JWh+f3vCLogn1HDegxEXE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:P06197 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314463|imex:IM-14275-52 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 crc64:6E2E62252B3CB5E2 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 intact-crc:A067A209B5A8125D|rigid:hMnERPfQY9Lef7C7u64fU46EjwY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12116 uniprotkb:P06197 intact:EBI-19306|uniprotkb:D6VS91|ensemblfungi:YDR105C intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W psi-mi:tms1_yeast(display_long)|uniprotkb:YDR105C(locus name)|uniprotkb:TMS1(gene name)|psi-mi:TMS1(display_short) psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314485|imex:IM-14275-54 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002512|ensemblfungi:YDR105C(gene)|ensemblfungi:YDR105C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR005016(TMS membrane protein/tumour differentially expressed protein)|interpro:IPR029559|reactome:R-SCE-977347|refseq:NP_010390.3|dip:DIP-5198N|mint:Q12116 refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 psi-mi:"MI:0469"(intact) crc64:DFA9011F9D56EEDE crc64:6E2E62252B3CB5E2 figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2r+KaCny/GXJUQ87u+f97/LLn+k559292 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 intact-crc:E73461CB01D3264E|rigid:g0JNXA3itPGmGEvoyYLbyxBU0qA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99287 uniprotkb:P06197 intact:EBI-37523|uniprotkb:D6W2M3|ensemblfungi:YOR165W intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W psi-mi:sey1_yeast(display_long)|uniprotkb:SEY1(gene name)|psi-mi:SEY1(display_short)|uniprotkb:YOR165W(locus name)|uniprotkb:Synthetic enhancer of YOP1 protein(gene name synonym)|uniprotkb:O3590(orf name) psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314496|imex:IM-14275-55 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014808.1|sgd:S000005691|dip:DIP-49373N|mint:Q99287|ensemblfungi:YOR165W(gene)|ensemblfungi:YOR165W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0061024"(membrane organization)|go:"GO:0071944"(cell periphery)|interpro:IPR008803(Root hair defective 3 GTP-binding)|interpro:IPR027417|interpro:IPR030386 refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 psi-mi:"MI:0469"(intact) crc64:DEC0C9EC3AB172DF crc64:6E2E62252B3CB5E2 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zFsgalfyUvAuuV51vChJjraiQmI559292 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 intact-crc:A0952F93D17B42DA|rigid:11vmFX2nekoF23S58zBSvJjF4Q4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06197 uniprotkb:Q05359 intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314474|imex:IM-14275-53 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:6E2E62252B3CB5E2 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 intact-crc:B0DE8F89285F2C09|rigid:If3ipVYToRXlUkpKcOtOqWAY4dM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06244 uniprotkb:P06244 intact:EBI-9458|uniprotkb:P11595|ensemblfungi:YJL164C|uniprotkb:D6VW23|uniprotkb:Q2VQW1 intact:EBI-9458|uniprotkb:P11595|ensemblfungi:YJL164C|uniprotkb:D6VW23|uniprotkb:Q2VQW1 psi-mi:kapa_yeast(display_long)|uniprotkb:TPK1(gene name)|psi-mi:TPK1(display_short)|uniprotkb:PKA1(gene name synonym)|uniprotkb:SRA3(gene name synonym)|uniprotkb:YJL164C(locus name)|uniprotkb:J0541(orf name)|uniprotkb:CDC25-suppressing protein kinase(gene name synonym)|uniprotkb:PK-25(gene name synonym) psi-mi:kapa_yeast(display_long)|uniprotkb:TPK1(gene name)|psi-mi:TPK1(display_short)|uniprotkb:PKA1(gene name synonym)|uniprotkb:SRA3(gene name synonym)|uniprotkb:YJL164C(locus name)|uniprotkb:J0541(orf name)|uniprotkb:CDC25-suppressing protein kinase(gene name synonym)|uniprotkb:PK-25(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314507|imex:IM-14275-56 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:1FOT|ensemblfungi:YJL164C(gene)|ensemblfungi:YJL164C_mRNA(transcript)|refseq:NP_012371.2|sgd:S000003700|mint:P06244|dip:DIP-548N go:"GO:0000785"(chromatin)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:1FOT|ensemblfungi:YJL164C(gene)|ensemblfungi:YJL164C_mRNA(transcript)|refseq:NP_012371.2|sgd:S000003700|mint:P06244|dip:DIP-548N psi-mi:"MI:0469"(intact) crc64:D4E5C30D7F11458B crc64:D4E5C30D7F11458B figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Xz1objgQPrWVbwXt82fc/VOJxaI559292 rogid:Xz1objgQPrWVbwXt82fc/VOJxaI559292 intact-crc:D8CB7A36F6BDC711|rigid:dOM1IzST1JRIddjwyigfugivmy4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07278 uniprotkb:P06244 intact:EBI-9475|ensemblfungi:YIL033C|uniprotkb:D6VVP9 intact:EBI-9458|uniprotkb:P11595|ensemblfungi:YJL164C|uniprotkb:D6VW23|uniprotkb:Q2VQW1 psi-mi:kapr_yeast(display_long)|uniprotkb:YIL033C(locus name)|uniprotkb:BCY1(gene name)|psi-mi:BCY1(display_short)|uniprotkb:REG1(gene name synonym)|uniprotkb:SRA1(gene name synonym)|uniprotkb:Bypass of cyclase mutations protein 1(gene name synonym)|uniprotkb:Protein kinase A regulatory subunit(gene name synonym) psi-mi:kapa_yeast(display_long)|uniprotkb:TPK1(gene name)|psi-mi:TPK1(display_short)|uniprotkb:PKA1(gene name synonym)|uniprotkb:SRA3(gene name synonym)|uniprotkb:YJL164C(locus name)|uniprotkb:J0541(orf name)|uniprotkb:CDC25-suppressing protein kinase(gene name synonym)|uniprotkb:PK-25(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314518|imex:IM-14275-57 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YIL033C(gene)|ensemblfungi:YIL033C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0030552"(cAMP binding)|go:"GO:0036278"(positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0061406"(positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|rcsb pdb:3OF1|rcsb pdb:6XQK|refseq:NP_012231.1|sgd:S000001295|mint:P07278|dip:DIP-551N go:"GO:0000785"(chromatin)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:1FOT|ensemblfungi:YJL164C(gene)|ensemblfungi:YJL164C_mRNA(transcript)|refseq:NP_012371.2|sgd:S000003700|mint:P06244|dip:DIP-548N psi-mi:"MI:0469"(intact) crc64:6D7D97D8E4340AF3 crc64:D4E5C30D7F11458B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rSJ37UFoFiaHqc/2W5eYNx1qpbg559292 rogid:Xz1objgQPrWVbwXt82fc/VOJxaI559292 intact-crc:97BA470D9DAB7622|rigid:mO7CjOSmIKTPpek/bK7RV0LjnHs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00816 uniprotkb:P06782 intact:EBI-8270|uniprotkb:D6VS13|ensemblfungi:YDR028C intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W psi-mi:reg1_yeast(display_long)|uniprotkb:PZF240(gene name synonym)|uniprotkb:SPP43(gene name synonym)|uniprotkb:SRN1(gene name synonym)|uniprotkb:YD9813.06C(orf name)|uniprotkb:YDR028C(locus name)|uniprotkb:REG1(gene name)|psi-mi:REG1(display_short)|uniprotkb:HEX2(gene name synonym)|uniprotkb:Protein HEX2(gene name synonym)|uniprotkb:Second-site suppressor of the rna1-1 mutation 1(gene name synonym) psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314529|imex:IM-14275-58 author score:97.40 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010311.1|sgd:S000002435|dip:DIP-2513N|mint:Q00816|ensemblfungi:YDR028C(gene)|ensemblfungi:YDR028C_mRNA(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005773"(vacuole)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007039"(protein catabolic process in the vacuole)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|interpro:IPR013860(Protein of unknown function DUF1752, fungi) refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782 psi-mi:"MI:0469"(intact) crc64:0D4AAC75E111B346 crc64:F5C63565C986C4E3 figure legend:tables S3 and S4|author-confidence:97.40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1ozfVSXyn7y5fR411wXk3gX8EfU559292 rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292 intact-crc:A07E4A923BC264B2|rigid:LcUlOURj6uTkeRZwfhFw5aIwaGY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04902 uniprotkb:P06784 intact:EBI-27696|uniprotkb:D6W0E9|ensemblfungi:YMR322C intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W psi-mi:sno4_yeast(display_long)|uniprotkb:SNO4(gene name)|psi-mi:SNO4(display_short)|uniprotkb:Glyoxalase 3 homolog 4(gene name synonym)|uniprotkb:HSP34(gene name synonym)|uniprotkb:Heat shock protein 34(gene name synonym)|uniprotkb:SNZ proximal open reading frame 4(gene name synonym)|uniprotkb:YM9924.14C(orf name)|uniprotkb:YMR322C(locus name) psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314540|imex:IM-14275-59 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014055.1|sgd:S000004941|dip:DIP-1968N|mint:Q04902|ensemblfungi:YMR322C(gene)|ensemblfungi:YMR322C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0019172"(glyoxalase III activity)|go:"GO:0031669"(cellular response to nutrient levels)|interpro:IPR029062 refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784 psi-mi:"MI:0469"(intact) - crc64:C8A75899CFBE8BDE figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZTVVFn1f7N6lvR7gGEOsvvHEM/k559292 rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292 intact-crc:A869C6BDEA290550|rigid:leC+iHmWhuq//myoQlKDEhiYi24 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06786 uniprotkb:P20051 intact:EBI-19352|uniprotkb:D6W191|ensemblfungi:YNL088W intact:EBI-14380|uniprotkb:D6VZ56|ensemblfungi:YLR420W psi-mi:top2_yeast(display_long)|uniprotkb:TOP2(gene name)|psi-mi:TOP2(display_short)|uniprotkb:TOR3(gene name synonym)|uniprotkb:YNL088W(locus name)|uniprotkb:N2244(orf name)|uniprotkb:DNA topoisomerase II(gene name synonym) psi-mi:pyrc_yeast(display_long)|uniprotkb:L9931.1(orf name)|uniprotkb:YLR420W(locus name)|uniprotkb:URA4(gene name)|psi-mi:URA4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314551|imex:IM-14275-60 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005032|ensemblfungi:YNL088W(gene)|ensemblfungi:YNL088W_mRNA(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000819"(sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006265"(DNA topological change)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031055"(chromatin remodeling at centromere)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0097046"(replication fork progression beyond termination site)|go:"GO:0097047"(DNA replication termination region)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR006171(TOPRIM)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018522|interpro:IPR020568|interpro:IPR031660|interpro:IPR034157|interpro:IPR036890|rcsb pdb:1BGW|rcsb pdb:1BJT|rcsb pdb:1PVG|rcsb pdb:1QZR|rcsb pdb:2RGR|rcsb pdb:3L4J|rcsb pdb:3L4K|rcsb pdb:4GFH|reactome:R-SCE-4615885|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|refseq:NP_014311.3|dip:DIP-2300N|mint:P06786 ensemblfungi:YLR420W(gene)|ensemblfungi:YLR420W_mRNA(transcript)|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006221"(pyrimidine nucleotide biosynthetic process)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR004721(Dihydroorotase homodimeric type)|interpro:IPR032466|rcsb pdb:6L0A|rcsb pdb:6L0B|rcsb pdb:6L0F|rcsb pdb:6L0G|rcsb pdb:6L0H|rcsb pdb:6L0I|rcsb pdb:6L0J|rcsb pdb:6L0K|rcsb pdb:7CA0|rcsb pdb:7CA1|refseq:NP_013524.1|sgd:S000004412|mint:P20051|dip:DIP-5074N psi-mi:"MI:0469"(intact) crc64:0E29EB8B89AA1387 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XKHvaF2HxChXbspQofpg5T6iZ+g559292 rogid:JG5LhBH1JIglT/rsaJC7ehYxa+Q559292 intact-crc:A5EBF54B1042CF88|rigid:EMPH3ihbH++lECnVoWNHto3to1M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07213 uniprotkb:P0C268 intact:EBI-12551|uniprotkb:D6W162|ensemblfungi:YNL121C|uniprotkb:B0KZR5|uniprotkb:B0KZS4|uniprotkb:B0KZU2|uniprotkb:B0KZY7|uniprotkb:B0KZZ6|uniprotkb:B0L005|uniprotkb:B0L023 intact:EBI-2044092|uniprotkb:D6VPV9|ensemblfungi:YBL039W-B psi-mi:tom70_yeast(display_long)|uniprotkb:TOM70(gene name)|psi-mi:TOM70(display_short)|uniprotkb:MAS70(gene name synonym)|uniprotkb:YNL121C(locus name)|uniprotkb:N1905(orf name)|uniprotkb:OMP1(gene name synonym)|uniprotkb:70 kDa mitochondrial outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 70 kDa subunit(gene name synonym) psi-mi:yb39b_yeast(display_long)|uniprotkb:YBL039W-B(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314562|imex:IM-14275-61 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR005687(Mitochondrial import translocase, subunit Tom70)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:2GW1|ensemblfungi:YNL121C(gene)|ensemblfungi:YNL121C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|refseq:NP_014278.3|sgd:S000005065|dip:DIP-2301N|mint:P07213 sgd:S000028517|refseq:NP_878045.1|mint:P0C268|ensemblfungi:YBL039W-B(gene)|ensemblfungi:YBL039W-B_mRNA(transcript)|go:"GO:0005777"(peroxisome) psi-mi:"MI:0469"(intact) crc64:664B8FC32CCE39A2 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0AbL99N4pd8IencG4+mcRH/QKOU559292 rogid:EfowKSHyZ6Fgw3vWQ74mzPwXTbQ559292 intact-crc:14221613A9FDA343|rigid:M+FeOVDhC60/fCkFd0dkcvzjdmY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07213 uniprotkb:P32332 intact:EBI-12551|uniprotkb:D6W162|ensemblfungi:YNL121C|uniprotkb:B0KZR5|uniprotkb:B0KZS4|uniprotkb:B0KZU2|uniprotkb:B0KZY7|uniprotkb:B0KZZ6|uniprotkb:B0L005|uniprotkb:B0L023 intact:EBI-12421|ensemblfungi:YKL120W|uniprotkb:D6VXH0 psi-mi:tom70_yeast(display_long)|uniprotkb:TOM70(gene name)|psi-mi:TOM70(display_short)|uniprotkb:MAS70(gene name synonym)|uniprotkb:YNL121C(locus name)|uniprotkb:N1905(orf name)|uniprotkb:OMP1(gene name synonym)|uniprotkb:70 kDa mitochondrial outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 70 kDa subunit(gene name synonym) psi-mi:oac1_yeast(display_long)|uniprotkb:OAC1(gene name)|psi-mi:OAC1(display_short)|uniprotkb:PMT(gene name synonym)|uniprotkb:PMT1(gene name synonym)|uniprotkb:YKL120W(locus name)|uniprotkb:YKL522(orf name)|uniprotkb:Mitochondrial carrier protein PMT(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314573|imex:IM-14275-62 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR005687(Mitochondrial import translocase, subunit Tom70)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:2GW1|ensemblfungi:YNL121C(gene)|ensemblfungi:YNL121C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|refseq:NP_014278.3|sgd:S000005065|dip:DIP-2301N|mint:P07213 ensemblfungi:YKL120W(gene)|go:"GO:0034658"(isopropylmalate transmembrane transporter activity)|go:"GO:0034659"(isopropylmalate transport)|ensemblfungi:YKL120W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:1901239"("malonate(1-) transmembrane transporter activity")|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0016021"(integral component of membrane)|refseq:NP_012802.1|sgd:S000001603|mint:P32332|dip:DIP-5417N psi-mi:"MI:0469"(intact) crc64:664B8FC32CCE39A2 crc64:696193F8979266AE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0AbL99N4pd8IencG4+mcRH/QKOU559292 rogid:GtUAWnmuI/96DfRfBwH6Zw+IdGc559292 intact-crc:B4468949F3983DF3|rigid:xFPb/9Rsyi4oRo3Z9YMTmux8JdI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54783 uniprotkb:P07213 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 intact:EBI-12551|uniprotkb:D6W162|ensemblfungi:YNL121C|uniprotkb:B0KZR5|uniprotkb:B0KZS4|uniprotkb:B0KZU2|uniprotkb:B0KZY7|uniprotkb:B0KZZ6|uniprotkb:B0L005|uniprotkb:B0L023 psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:tom70_yeast(display_long)|uniprotkb:TOM70(gene name)|psi-mi:TOM70(display_short)|uniprotkb:MAS70(gene name synonym)|uniprotkb:YNL121C(locus name)|uniprotkb:N1905(orf name)|uniprotkb:OMP1(gene name synonym)|uniprotkb:70 kDa mitochondrial outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 70 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314584|imex:IM-14275-63 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR005687(Mitochondrial import translocase, subunit Tom70)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:2GW1|ensemblfungi:YNL121C(gene)|ensemblfungi:YNL121C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|refseq:NP_014278.3|sgd:S000005065|dip:DIP-2301N|mint:P07213 psi-mi:"MI:0469"(intact) - crc64:664B8FC32CCE39A2 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 rogid:0AbL99N4pd8IencG4+mcRH/QKOU559292 intact-crc:9A459BE9F619A46E|rigid:HOMcWBLYkd2bKyFhNnn5rFM4/FE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27999 uniprotkb:P07273 intact:EBI-15798|ensemblfungi:YGL070C|uniprotkb:D6VU72 intact:EBI-19168|uniprotkb:P24535|uniprotkb:D6VU96|ensemblfungi:YGL043W psi-mi:rpb9_yeast(display_long)|uniprotkb:YGL070C(locus name)|uniprotkb:RPB9(gene name)|psi-mi:RPB9(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit 9(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 14.2 kDa polypeptide(gene name synonym)|uniprotkb:B12.6(gene name synonym) psi-mi:tfs2_yeast(display_long)|uniprotkb:YGL043W(locus name)|uniprotkb:DST1(gene name)|psi-mi:DST1(display_short)|uniprotkb:PPR2(gene name synonym)|uniprotkb:DNA strand transfer protein alpha(gene name synonym)|uniprotkb:DNA strand transferase 1(gene name synonym)|uniprotkb:Pyrimidine pathway regulatory protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314595|imex:IM-14275-64 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4BY7|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4A3E|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4A3F|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:4A3G|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:4A3K|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:4A3L|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|ensemblfungi:YGL070C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|ensemblfungi:YGL070C(gene)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3GTM|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:1TWH|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:5VVR|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|refseq:NP_011445.1|sgd:S000003038|dip:DIP-610N|mint:P27999 refseq:NP_011472.1|sgd:S000003011|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR003618(Transcription elongation factor S-II, central region)|interpro:IPR006289(Transcription elongation factor, TFIIS)|interpro:IPR017923|interpro:IPR035100|interpro:IPR035441|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR036575|rcsb pdb:1ENW|rcsb pdb:1EO0|rcsb pdb:1PQV|rcsb pdb:1Y1V|rcsb pdb:1Y1Y|rcsb pdb:3GTM|rcsb pdb:3PO3|rcsb pdb:5FMF|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-75955|ensemblfungi:YGL043W(gene)|ensemblfungi:YGL043W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0031564"(transcription antitermination)|dip:DIP-2307N|mint:P07273 psi-mi:"MI:0469"(intact) crc64:A80D69678A722881 crc64:D133938319C015FF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1j6EwrXe8/AF0PL2VTiTTCfWJDM559292 rogid:s65jOZBWFhznlfhv7ZWdN5Kp8aQ559292 intact-crc:F6C49E97992EA368|rigid:INTOqtLUSS8sUcsz5Qg0vcLK5do false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07278 uniprotkb:P06244 intact:EBI-9475|ensemblfungi:YIL033C|uniprotkb:D6VVP9 intact:EBI-9458|uniprotkb:P11595|ensemblfungi:YJL164C|uniprotkb:D6VW23|uniprotkb:Q2VQW1 psi-mi:kapr_yeast(display_long)|uniprotkb:YIL033C(locus name)|uniprotkb:BCY1(gene name)|psi-mi:BCY1(display_short)|uniprotkb:REG1(gene name synonym)|uniprotkb:SRA1(gene name synonym)|uniprotkb:Bypass of cyclase mutations protein 1(gene name synonym)|uniprotkb:Protein kinase A regulatory subunit(gene name synonym) psi-mi:kapa_yeast(display_long)|uniprotkb:TPK1(gene name)|psi-mi:TPK1(display_short)|uniprotkb:PKA1(gene name synonym)|uniprotkb:SRA3(gene name synonym)|uniprotkb:YJL164C(locus name)|uniprotkb:J0541(orf name)|uniprotkb:CDC25-suppressing protein kinase(gene name synonym)|uniprotkb:PK-25(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314606|imex:IM-14275-65 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YIL033C(gene)|ensemblfungi:YIL033C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0030552"(cAMP binding)|go:"GO:0036278"(positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0061406"(positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|rcsb pdb:3OF1|rcsb pdb:6XQK|refseq:NP_012231.1|sgd:S000001295|mint:P07278|dip:DIP-551N go:"GO:0000785"(chromatin)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:1FOT|ensemblfungi:YJL164C(gene)|ensemblfungi:YJL164C_mRNA(transcript)|refseq:NP_012371.2|sgd:S000003700|mint:P06244|dip:DIP-548N psi-mi:"MI:0469"(intact) crc64:6D7D97D8E4340AF3 crc64:D4E5C30D7F11458B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rSJ37UFoFiaHqc/2W5eYNx1qpbg559292 rogid:Xz1objgQPrWVbwXt82fc/VOJxaI559292 intact-crc:167BBD3583C642AC|rigid:mO7CjOSmIKTPpek/bK7RV0LjnHs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07560 uniprotkb:P32465 intact:EBI-16858|uniprotkb:D6VTM4|ensemblfungi:YFL005W intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 psi-mi:sec4_yeast(display_long)|uniprotkb:SEC4(gene name)|psi-mi:SEC4(display_short)|uniprotkb:SRO6(gene name synonym)|uniprotkb:Suppressor of RHO3 protein 6(gene name synonym)|uniprotkb:YFL005W(locus name) psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314661|imex:IM-14275-70 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YFL005W(gene)|ensemblfungi:YFL005W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0006914"(autophagy)|go:"GO:0007107"(membrane addition at site of cytokinesis)|go:"GO:0009306"(protein secretion)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030133"(transport vesicle)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031321"(ascospore-type prospore assembly)|go:"GO:0031982"(vesicle)|go:"GO:0043332"(mating projection tip)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1G17|rcsb pdb:2EQB|rcsb pdb:2OCY|rcsb pdb:3CPH|rcsb pdb:4Z8Y|rcsb pdb:4ZDW|reactome:R-SCE-6798695|reactome:R-SCE-8873719|reactome:R-SCE-8876198|rcsb pdb:1G16|refseq:NP_116650.1|sgd:S000001889|dip:DIP-2492N|mint:P07560 ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N psi-mi:"MI:0469"(intact) crc64:7DEDF7DCC7533BA7 - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jJuZIOzwwlmNRExLIJtbs9vd/so559292 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 intact-crc:C554EE6E5DB28CD4|rigid:4ixv8hX3LA4NdXI5eBwhJ8kOApo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38328 uniprotkb:P07285 intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C intact:EBI-2096870|uniprotkb:D6VSY4|ensemblfungi:YDR354W psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:trpd_yeast(display_long)|uniprotkb:TRP4(gene name)|psi-mi:TRP4(display_short)|uniprotkb:D9476.4(orf name)|uniprotkb:YDR354W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314650|imex:IM-14275-69 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 sgd:S000002762|interpro:IPR005940(Anthranilate phosphoribosyl transferase)|interpro:IPR000312(Glycosyl transferase, family 3)|interpro:IPR017459(Glycosyl transferase, family 3, N-terminal)|refseq:NP_010641.3|mint:P07285|interpro:IPR035902|ensemblfungi:YDR354W(gene)|ensemblfungi:YDR354W_mRNA(transcript)|go:"GO:0000162"(tryptophan biosynthetic process)|go:"GO:0004048"(anthranilate phosphoribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|rcsb pdb:7DSJ|rcsb pdb:7DSM|rcsb pdb:7DSO|rcsb pdb:7DSP|rcsb pdb:7DSR psi-mi:"MI:0469"(intact) crc64:D75C6BB8EC35EEDF - figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 rogid:Ir9bWI7njXj8o4MEAkaTeiXw1H4559292 intact-crc:B74925B6A5FB1E11|rigid:QUCTHRKY/n5Ub7rrFwFqTc9OY7M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07285 uniprotkb:P31386 intact:EBI-2096870|uniprotkb:D6VSY4|ensemblfungi:YDR354W intact:EBI-2046012|uniprotkb:D6VPJ8|ensemblfungi:YAL020C psi-mi:trpd_yeast(display_long)|uniprotkb:TRP4(gene name)|psi-mi:TRP4(display_short)|uniprotkb:D9476.4(orf name)|uniprotkb:YDR354W(locus name) psi-mi:ats1_yeast(display_long)|uniprotkb:Alpha-tubulin suppressor 1(gene name synonym)|uniprotkb:ATS1(gene name)|psi-mi:ATS1(display_short)|uniprotkb:KTI13(gene name synonym)|uniprotkb:Kluyveromyces lactis toxin-insensitive protein 13(gene name synonym)|uniprotkb:FUN28(orf name)|uniprotkb:YAL006(orf name)|uniprotkb:YAL020C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314639|imex:IM-14275-68 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002762|interpro:IPR005940(Anthranilate phosphoribosyl transferase)|interpro:IPR000312(Glycosyl transferase, family 3)|interpro:IPR017459(Glycosyl transferase, family 3, N-terminal)|refseq:NP_010641.3|mint:P07285|interpro:IPR035902|ensemblfungi:YDR354W(gene)|ensemblfungi:YDR354W_mRNA(transcript)|go:"GO:0000162"(tryptophan biosynthetic process)|go:"GO:0004048"(anthranilate phosphoribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|rcsb pdb:7DSJ|rcsb pdb:7DSM|rcsb pdb:7DSO|rcsb pdb:7DSP|rcsb pdb:7DSR refseq:NP_009382.2|sgd:S000000018|dip:DIP-7890N|mint:P31386|ensemblfungi:YAL020C(gene)|ensemblfungi:YAL020C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4D4O|rcsb pdb:4D4P|rcsb pdb:4D4Q|rcsb pdb:4X33 psi-mi:"MI:0469"(intact) - crc64:3C6F4BE180479096 figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ir9bWI7njXj8o4MEAkaTeiXw1H4559292 rogid:O36Rg2N1h1h4aVs0tSGc8xtbAxQ559292 intact-crc:0113460E5A567408|rigid:qADxcw8kKCZbE1nwy7XjR7RnI/s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07278 uniprotkb:P07278 intact:EBI-9475|ensemblfungi:YIL033C|uniprotkb:D6VVP9 intact:EBI-9475|ensemblfungi:YIL033C|uniprotkb:D6VVP9 psi-mi:kapr_yeast(display_long)|uniprotkb:YIL033C(locus name)|uniprotkb:BCY1(gene name)|psi-mi:BCY1(display_short)|uniprotkb:REG1(gene name synonym)|uniprotkb:SRA1(gene name synonym)|uniprotkb:Bypass of cyclase mutations protein 1(gene name synonym)|uniprotkb:Protein kinase A regulatory subunit(gene name synonym) psi-mi:kapr_yeast(display_long)|uniprotkb:YIL033C(locus name)|uniprotkb:BCY1(gene name)|psi-mi:BCY1(display_short)|uniprotkb:REG1(gene name synonym)|uniprotkb:SRA1(gene name synonym)|uniprotkb:Bypass of cyclase mutations protein 1(gene name synonym)|uniprotkb:Protein kinase A regulatory subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314628|imex:IM-14275-67 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YIL033C(gene)|ensemblfungi:YIL033C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0030552"(cAMP binding)|go:"GO:0036278"(positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0061406"(positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|rcsb pdb:3OF1|rcsb pdb:6XQK|refseq:NP_012231.1|sgd:S000001295|mint:P07278|dip:DIP-551N ensemblfungi:YIL033C(gene)|ensemblfungi:YIL033C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0030552"(cAMP binding)|go:"GO:0036278"(positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0061406"(positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|rcsb pdb:3OF1|rcsb pdb:6XQK|refseq:NP_012231.1|sgd:S000001295|mint:P07278|dip:DIP-551N psi-mi:"MI:0469"(intact) crc64:6D7D97D8E4340AF3 crc64:6D7D97D8E4340AF3 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rSJ37UFoFiaHqc/2W5eYNx1qpbg559292 rogid:rSJ37UFoFiaHqc/2W5eYNx1qpbg559292 intact-crc:67E7A85B8E465B2F|rigid:vIoa2MoQKXZJI1R1NavT/DJxq3c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07278 uniprotkb:P06245 intact:EBI-9475|ensemblfungi:YIL033C|uniprotkb:D6VVP9 intact:EBI-9465|ensemblfungi:YPL203W|uniprotkb:D6W3G6 psi-mi:kapr_yeast(display_long)|uniprotkb:YIL033C(locus name)|uniprotkb:BCY1(gene name)|psi-mi:BCY1(display_short)|uniprotkb:REG1(gene name synonym)|uniprotkb:SRA1(gene name synonym)|uniprotkb:Bypass of cyclase mutations protein 1(gene name synonym)|uniprotkb:Protein kinase A regulatory subunit(gene name synonym) psi-mi:kapb_yeast(display_long)|uniprotkb:YPL203W(locus name)|uniprotkb:TPK2(gene name)|psi-mi:TPK2(display_short)|uniprotkb:PKA2(gene name synonym)|uniprotkb:YKR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314617|imex:IM-14275-66 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YIL033C(gene)|ensemblfungi:YIL033C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0030552"(cAMP binding)|go:"GO:0036278"(positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0061406"(positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|rcsb pdb:3OF1|rcsb pdb:6XQK|refseq:NP_012231.1|sgd:S000001295|mint:P07278|dip:DIP-551N ensemblfungi:YPL203W(gene)|ensemblfungi:YPL203W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_015121.1|sgd:S000006124|mint:P06245|dip:DIP-549N psi-mi:"MI:0469"(intact) crc64:6D7D97D8E4340AF3 crc64:1BC255C6D0F33137 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rSJ37UFoFiaHqc/2W5eYNx1qpbg559292 rogid:9Lh+GL9j37UYnEst/qBIiSKPMd4559292 intact-crc:177BBD313EBFDAEE|rigid:pTXGB1MRsxOgapViDQY+4khACIc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07560 uniprotkb:Q12462 intact:EBI-16858|uniprotkb:D6VTM4|ensemblfungi:YFL005W intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C psi-mi:sec4_yeast(display_long)|uniprotkb:SEC4(gene name)|psi-mi:SEC4(display_short)|uniprotkb:SRO6(gene name synonym)|uniprotkb:Suppressor of RHO3 protein 6(gene name synonym)|uniprotkb:YFL005W(locus name) psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314716|imex:IM-14275-75 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YFL005W(gene)|ensemblfungi:YFL005W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0006914"(autophagy)|go:"GO:0007107"(membrane addition at site of cytokinesis)|go:"GO:0009306"(protein secretion)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030133"(transport vesicle)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031321"(ascospore-type prospore assembly)|go:"GO:0031982"(vesicle)|go:"GO:0043332"(mating projection tip)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1G17|rcsb pdb:2EQB|rcsb pdb:2OCY|rcsb pdb:3CPH|rcsb pdb:4Z8Y|rcsb pdb:4ZDW|reactome:R-SCE-6798695|reactome:R-SCE-8873719|reactome:R-SCE-8876198|rcsb pdb:1G16|refseq:NP_116650.1|sgd:S000001889|dip:DIP-2492N|mint:P07560 refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) psi-mi:"MI:0469"(intact) crc64:7DEDF7DCC7533BA7 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jJuZIOzwwlmNRExLIJtbs9vd/so559292 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 intact-crc:2B34FC514A52B83D|rigid:Xuabi1vzL0tv3LLNpiDJZIovwiU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04322 uniprotkb:P07560 intact:EBI-27427|uniprotkb:D6W016|ensemblfungi:YMR192W intact:EBI-16858|uniprotkb:D6VTM4|ensemblfungi:YFL005W psi-mi:gyl1_yeast(display_long)|uniprotkb:YMR192W(locus name)|uniprotkb:YM9646.04(orf name)|uniprotkb:GYL1(gene name)|psi-mi:GYL1(display_short)|uniprotkb:APP2(gene name synonym)|uniprotkb:GYP5-like protein 1(gene name synonym) psi-mi:sec4_yeast(display_long)|uniprotkb:SEC4(gene name)|psi-mi:SEC4(display_short)|uniprotkb:SRO6(gene name synonym)|uniprotkb:Suppressor of RHO3 protein 6(gene name synonym)|uniprotkb:YFL005W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314705|imex:IM-14275-74 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q04322|refseq:NP_013917.1|sgd:S000004804|dip:DIP-2891N|ensemblfungi:YMR192W(gene)|ensemblfungi:YMR192W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0017157"(regulation of exocytosis)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969 ensemblfungi:YFL005W(gene)|ensemblfungi:YFL005W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0006914"(autophagy)|go:"GO:0007107"(membrane addition at site of cytokinesis)|go:"GO:0009306"(protein secretion)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030133"(transport vesicle)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031321"(ascospore-type prospore assembly)|go:"GO:0031982"(vesicle)|go:"GO:0043332"(mating projection tip)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1G17|rcsb pdb:2EQB|rcsb pdb:2OCY|rcsb pdb:3CPH|rcsb pdb:4Z8Y|rcsb pdb:4ZDW|reactome:R-SCE-6798695|reactome:R-SCE-8873719|reactome:R-SCE-8876198|rcsb pdb:1G16|refseq:NP_116650.1|sgd:S000001889|dip:DIP-2492N|mint:P07560 psi-mi:"MI:0469"(intact) - crc64:7DEDF7DCC7533BA7 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:JXXEUKwB+ysZExb+8We4yeNrftM559292 rogid:jJuZIOzwwlmNRExLIJtbs9vd/so559292 intact-crc:82916C122AB44F73|rigid:BycSp4ePHJxBMgWvozNri4f0B60 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07560 uniprotkb:P54783 intact:EBI-16858|uniprotkb:D6VTM4|ensemblfungi:YFL005W intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:sec4_yeast(display_long)|uniprotkb:SEC4(gene name)|psi-mi:SEC4(display_short)|uniprotkb:SRO6(gene name synonym)|uniprotkb:Suppressor of RHO3 protein 6(gene name synonym)|uniprotkb:YFL005W(locus name) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314694|imex:IM-14275-73 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YFL005W(gene)|ensemblfungi:YFL005W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0006914"(autophagy)|go:"GO:0007107"(membrane addition at site of cytokinesis)|go:"GO:0009306"(protein secretion)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030133"(transport vesicle)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031321"(ascospore-type prospore assembly)|go:"GO:0031982"(vesicle)|go:"GO:0043332"(mating projection tip)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1G17|rcsb pdb:2EQB|rcsb pdb:2OCY|rcsb pdb:3CPH|rcsb pdb:4Z8Y|rcsb pdb:4ZDW|reactome:R-SCE-6798695|reactome:R-SCE-8873719|reactome:R-SCE-8876198|rcsb pdb:1G16|refseq:NP_116650.1|sgd:S000001889|dip:DIP-2492N|mint:P07560 go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) crc64:7DEDF7DCC7533BA7 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jJuZIOzwwlmNRExLIJtbs9vd/so559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:9DEEBCE42EBE520D|rigid:6qEO1oqjHzKIvm22XSWo2hHYMPk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07560 uniprotkb:P39958 intact:EBI-16858|uniprotkb:D6VTM4|ensemblfungi:YFL005W intact:EBI-7517|uniprotkb:D3DM41|ensemblfungi:YER136W psi-mi:sec4_yeast(display_long)|uniprotkb:SEC4(gene name)|psi-mi:SEC4(display_short)|uniprotkb:SRO6(gene name synonym)|uniprotkb:Suppressor of RHO3 protein 6(gene name synonym)|uniprotkb:YFL005W(locus name) psi-mi:gdi1_yeast(display_long)|uniprotkb:YER136W(locus name)|uniprotkb:GDI1(gene name)|psi-mi:GDI1(display_short)|uniprotkb:SEC19(gene name synonym)|uniprotkb:Secretory pathway GDP dissociation inhibitor(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314683|imex:IM-14275-72 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YFL005W(gene)|ensemblfungi:YFL005W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0006914"(autophagy)|go:"GO:0007107"(membrane addition at site of cytokinesis)|go:"GO:0009306"(protein secretion)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030133"(transport vesicle)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031321"(ascospore-type prospore assembly)|go:"GO:0031982"(vesicle)|go:"GO:0043332"(mating projection tip)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1G17|rcsb pdb:2EQB|rcsb pdb:2OCY|rcsb pdb:3CPH|rcsb pdb:4Z8Y|rcsb pdb:4ZDW|reactome:R-SCE-6798695|reactome:R-SCE-8873719|reactome:R-SCE-8876198|rcsb pdb:1G16|refseq:NP_116650.1|sgd:S000001889|dip:DIP-2492N|mint:P07560 refseq:NP_011062.1|sgd:S000000938|mint:P39958|dip:DIP-785N|ensemblfungi:YER136W(gene)|ensemblfungi:YER136W_mRNA(transcript)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|rcsb pdb:1UKV|rcsb pdb:2BCG|rcsb pdb:3CPH|rcsb pdb:3CPI|rcsb pdb:3CPJ|reactome:R-SCE-6798695|reactome:R-SCE-8876198 psi-mi:"MI:0469"(intact) crc64:7DEDF7DCC7533BA7 crc64:48CF8D45FC031772 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jJuZIOzwwlmNRExLIJtbs9vd/so559292 rogid:AkWsG1VUBGxajiAMw0e0mOljZ6s559292 intact-crc:DF854CA4D7908350|rigid:749ShvQpXzaN14mKaWXbc6wtYzA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07560 uniprotkb:P32864 intact:EBI-16858|uniprotkb:D6VTM4|ensemblfungi:YFL005W intact:EBI-14799|uniprotkb:Q06761|uniprotkb:D6W363|ensemblfungi:YOR370C psi-mi:sec4_yeast(display_long)|uniprotkb:SEC4(gene name)|psi-mi:SEC4(display_short)|uniprotkb:SRO6(gene name synonym)|uniprotkb:Suppressor of RHO3 protein 6(gene name synonym)|uniprotkb:YFL005W(locus name) psi-mi:raep_yeast(display_long)|uniprotkb:YOR370C(locus name)|uniprotkb:MRS6(gene name)|psi-mi:MRS6(display_short)|uniprotkb:MSI4(gene name synonym)|uniprotkb:Rab escort protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314672|imex:IM-14275-71 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YFL005W(gene)|ensemblfungi:YFL005W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0006914"(autophagy)|go:"GO:0007107"(membrane addition at site of cytokinesis)|go:"GO:0009306"(protein secretion)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030133"(transport vesicle)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031321"(ascospore-type prospore assembly)|go:"GO:0031982"(vesicle)|go:"GO:0043332"(mating projection tip)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1G17|rcsb pdb:2EQB|rcsb pdb:2OCY|rcsb pdb:3CPH|rcsb pdb:4Z8Y|rcsb pdb:4ZDW|reactome:R-SCE-6798695|reactome:R-SCE-8873719|reactome:R-SCE-8876198|rcsb pdb:1G16|refseq:NP_116650.1|sgd:S000001889|dip:DIP-2492N|mint:P07560 refseq:NP_015015.1|sgd:S000005897|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005968"(Rab-protein geranylgeranyltransferase complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR017230(Rab protein geranylgeranyltransferase, component A, fungi)|interpro:IPR018203|interpro:IPR036188|reactome:R-SCE-6803205|reactome:R-SCE-8873719|reactome:R-SCE-8876198|ensemblfungi:YOR370C(gene)|ensemblfungi:YOR370C_mRNA(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|dip:DIP-2246N|mint:P32864 psi-mi:"MI:0469"(intact) crc64:7DEDF7DCC7533BA7 crc64:30BB7FFF8D712FFD figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jJuZIOzwwlmNRExLIJtbs9vd/so559292 rogid:quu5u+3WZxRJAobk3H2EERRUqKU559292 intact-crc:8D23D4B40DEF6AF3|rigid:VkPQm+tZgvJP3z4FCavSFzBA0UE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08004 uniprotkb:P39719 intact:EBI-4618|uniprotkb:D6W0Z5|ensemblfungi:YNL192W intact:EBI-20703|uniprotkb:Q05165|uniprotkb:D6VPG5|ensemblfungi:YAL053W psi-mi:chs1_yeast(display_long)|uniprotkb:CHS1(gene name)|psi-mi:CHS1(display_short)|uniprotkb:YNL192W(locus name)|uniprotkb:N1404(orf name)|uniprotkb:Chitin-UDP acetyl-glucosaminyl transferase 1(gene name synonym) psi-mi:flc2_yeast(display_long)|uniprotkb:YAL053W(locus name)|uniprotkb:FLC2(gene name)|psi-mi:FLC2(display_short)|uniprotkb:FAD transporter 2(gene name synonym)|uniprotkb:TRP-like ion channel FLC2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314760|imex:IM-14275-79 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014207.2|sgd:S000005136|dip:DIP-4680N|mint:P08004|ensemblfungi:YNL192W(gene)|ensemblfungi:YNL192W_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004100"(chitin synthase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006031"(chitin biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030428"(cell septum)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0045009"(chitosome)|go:"GO:0071944"(cell periphery)|interpro:IPR004834(Chitin synthase)|interpro:IPR004835(Fungal chitin synthase)|interpro:IPR013616(Chitin synthase N-terminal)|interpro:IPR029044 refseq:NP_009348.2|sgd:S000000049|ensemblfungi:YAL053W(gene)|ensemblfungi:YAL053W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241|go:"GO:0055085"(transmembrane transport)|dip:DIP-6708N|mint:P39719 psi-mi:"MI:0469"(intact) crc64:C1856F3C0C857E07 - figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1O1Oa2/6aikiB3ELTCtgtd/tyxM559292 rogid:NOmMW54DNa0o7vM945DlZgVUy44559292 intact-crc:B0324ABDEF49F9F9|rigid:15QslcM+UV/9N39NCqMC8WrP+5c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07703 uniprotkb:P47035 intact:EBI-15831|ensemblfungi:YPR110C|uniprotkb:D6W4A9 intact:EBI-25953|uniprotkb:D6VWA8|ensemblfungi:YJL076W psi-mi:rpac1_yeast(display_long)|uniprotkb:RPC40(gene name)|psi-mi:RPC40(display_short)|uniprotkb:YPR110C(locus name)|uniprotkb:P8283.18(orf name)|uniprotkb:RPC5(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:C37(gene name synonym) psi-mi:net1_yeast(display_long)|uniprotkb:YJL076W(locus name)|uniprotkb:J1038(orf name)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:CFI1(gene name synonym)|uniprotkb:ESC5(gene name synonym)|uniprotkb:SRM8(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314749|imex:IM-14275-78 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPR110C(gene)|ensemblfungi:YPR110C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001056"(RNA polymerase III activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070893"(transposon integration)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR033901|interpro:IPR036603|interpro:IPR036643|rcsb pdb:4C2M|rcsb pdb:4C3I|rcsb pdb:4C3H|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5G5L|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-76061|reactome:R-SCE-76066|refseq:NP_015435.1|sgd:S000006314|dip:DIP-17N|mint:P07703 refseq:NP_012459.1|sgd:S000003612|mint:P47035|dip:DIP-5153N|ensemblfungi:YJL076W(gene)|ensemblfungi:YJL076W_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007000"(nucleolus organization)|go:"GO:0007049"(cell cycle)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0030869"(RENT complex)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0051301"(cell division)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR018844|interpro:IPR043185 psi-mi:"MI:0469"(intact) crc64:76A5D6784403E990 crc64:80EDF9A8065EB5A2 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:erepZ6yX0AYInV5koxEj9V9E2pI559292 rogid:yjUIbOfA/bCZE9nMIjYS1QTn6EI559292 intact-crc:D56595E7D09C7606|rigid:44LnSHvRAHO2BvqTms5vW+pNq8k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07703 uniprotkb:P28000 intact:EBI-15831|ensemblfungi:YPR110C|uniprotkb:D6W4A9 intact:EBI-15846|ensemblfungi:YNL113W|uniprotkb:D6W168 psi-mi:rpac1_yeast(display_long)|uniprotkb:RPC40(gene name)|psi-mi:RPC40(display_short)|uniprotkb:YPR110C(locus name)|uniprotkb:P8283.18(orf name)|uniprotkb:RPC5(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:C37(gene name synonym) psi-mi:rpac2_yeast(display_long)|uniprotkb:YNL113W(locus name)|uniprotkb:N1937(orf name)|uniprotkb:RPC19(gene name)|psi-mi:RPC19(display_short)|uniprotkb:DNA-directed RNA polymerases I and III 16 kDa polypeptide(gene name synonym)|uniprotkb:RPA19(gene name synonym)|uniprotkb:AC19(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314738|imex:IM-14275-77 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPR110C(gene)|ensemblfungi:YPR110C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001056"(RNA polymerase III activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070893"(transposon integration)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR033901|interpro:IPR036603|interpro:IPR036643|rcsb pdb:4C2M|rcsb pdb:4C3I|rcsb pdb:4C3H|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5G5L|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-76061|reactome:R-SCE-76066|refseq:NP_015435.1|sgd:S000006314|dip:DIP-17N|mint:P07703 rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:4C2M|rcsb pdb:5W66|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|ensemblfungi:YNL113W(gene)|ensemblfungi:YNL113W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR033898|interpro:IPR036603|refseq:NP_014286.1|rcsb pdb:6TUT|sgd:S000005057|dip:DIP-130N|mint:P28000 psi-mi:"MI:0469"(intact) crc64:76A5D6784403E990 crc64:0B048299A787EEDB figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:erepZ6yX0AYInV5koxEj9V9E2pI559292 rogid:5WE5tcol5BMb/TBn7MxNz1bVdGk559292 intact-crc:807FC6C02E29B4E1|rigid:xKu7We0DcH3NhIP+nYvOU6ku79I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10964 uniprotkb:P07703 intact:EBI-15730|uniprotkb:Q99330|uniprotkb:D6W336|ensemblfungi:YOR341W intact:EBI-15831|ensemblfungi:YPR110C|uniprotkb:D6W4A9 psi-mi:rpa1_yeast(display_long)|uniprotkb:RPA190(gene name)|psi-mi:RPA190(display_short)|uniprotkb:RPA1(gene name synonym)|uniprotkb:RRN1(gene name synonym)|uniprotkb:YOR341W(locus name)|uniprotkb:O6276(orf name)|uniprotkb:DNA-directed RNA polymerase I 190 kDa polypeptide(gene name synonym)|uniprotkb:DNA-directed RNA polymerase I largest subunit(gene name synonym) psi-mi:rpac1_yeast(display_long)|uniprotkb:RPC40(gene name)|psi-mi:RPC40(display_short)|uniprotkb:YPR110C(locus name)|uniprotkb:P8283.18(orf name)|uniprotkb:RPC5(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:C37(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314727|imex:IM-14275-76 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005868|refseq:NP_014986.3|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR015699(DNA-directed RNA pol I, largest subunit)|interpro:IPR038120|interpro:IPR042102|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|ensemblfungi:YOR341W(gene)|ensemblfungi:YOR341W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0008270"(zinc ion binding)|dip:DIP-999N|mint:P10964 ensemblfungi:YPR110C(gene)|ensemblfungi:YPR110C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001056"(RNA polymerase III activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070893"(transposon integration)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR033901|interpro:IPR036603|interpro:IPR036643|rcsb pdb:4C2M|rcsb pdb:4C3I|rcsb pdb:4C3H|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5G5L|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-76061|reactome:R-SCE-76066|refseq:NP_015435.1|sgd:S000006314|dip:DIP-17N|mint:P07703 psi-mi:"MI:0469"(intact) crc64:DF65A7AA459D5E6D crc64:76A5D6784403E990 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:krXuLY5fTE34McW4bnuPqns5Oy4559292 rogid:erepZ6yX0AYInV5koxEj9V9E2pI559292 intact-crc:E34B951D17A1D264|rigid:V8f9GYiHiJ0J1xU3zAiep+RwTh0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08678 uniprotkb:P08678 intact:EBI-5364|uniprotkb:D6VWH0|ensemblfungi:YJL005W intact:EBI-5364|uniprotkb:D6VWH0|ensemblfungi:YJL005W psi-mi:cyaa_yeast(display_long)|uniprotkb:CYR1(gene name)|psi-mi:CYR1(display_short)|uniprotkb:CDC35(gene name synonym)|uniprotkb:HSR1(gene name synonym)|uniprotkb:SRA4(gene name synonym)|uniprotkb:YJL005W(locus name)|uniprotkb:J1401(orf name)|uniprotkb:Adenylyl cyclase(gene name synonym)|uniprotkb:ATP pyrophosphate-lyase(gene name synonym) psi-mi:cyaa_yeast(display_long)|uniprotkb:CYR1(gene name)|psi-mi:CYR1(display_short)|uniprotkb:CDC35(gene name synonym)|uniprotkb:HSR1(gene name synonym)|uniprotkb:SRA4(gene name synonym)|uniprotkb:YJL005W(locus name)|uniprotkb:J1401(orf name)|uniprotkb:Adenylyl cyclase(gene name synonym)|uniprotkb:ATP pyrophosphate-lyase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314815|imex:IM-14275-84 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003542|refseq:NP_012529.3|dip:DIP-2317N|mint:P08678|ensemblfungi:YJL005W(gene)|ensemblfungi:YJL005W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0016791"(phosphatase activity)|interpro:IPR000159(Ras-association)|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR013716(Adenylate cyclase G-alpha binding)|interpro:IPR029787|interpro:IPR032675|interpro:IPR036457|reactome:R-SCE-199418|reactome:R-SCE-5223345 sgd:S000003542|refseq:NP_012529.3|dip:DIP-2317N|mint:P08678|ensemblfungi:YJL005W(gene)|ensemblfungi:YJL005W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0016791"(phosphatase activity)|interpro:IPR000159(Ras-association)|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR013716(Adenylate cyclase G-alpha binding)|interpro:IPR029787|interpro:IPR032675|interpro:IPR036457|reactome:R-SCE-199418|reactome:R-SCE-5223345 psi-mi:"MI:0469"(intact) crc64:BEAB7419AB6989D0 crc64:BEAB7419AB6989D0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jcjdcDnCxKuonhXVJ9cUa6cAiwA559292 rogid:jcjdcDnCxKuonhXVJ9cUa6cAiwA559292 intact-crc:CCD699F345A4C017|rigid:0ILTs8divCVYNVhHj/CSshnGJGc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08536 uniprotkb:P08536 intact:EBI-10753|uniprotkb:Q66R66|ensemblfungi:YJR010W|uniprotkb:D6VWI5 intact:EBI-10753|uniprotkb:Q66R66|ensemblfungi:YJR010W|uniprotkb:D6VWI5 psi-mi:met3_yeast(display_long)|uniprotkb:Sulfate adenylate transferase(gene name synonym)|uniprotkb:ATP-sulfurylase(gene name synonym)|uniprotkb:MET3(gene name)|psi-mi:MET3(display_short)|uniprotkb:YJR010W(locus name)|uniprotkb:J1436(orf name)|uniprotkb:Methionine-requiring protein 3(gene name synonym) psi-mi:met3_yeast(display_long)|uniprotkb:Sulfate adenylate transferase(gene name synonym)|uniprotkb:ATP-sulfurylase(gene name synonym)|uniprotkb:MET3(gene name)|psi-mi:MET3(display_short)|uniprotkb:YJR010W(locus name)|uniprotkb:J1436(orf name)|uniprotkb:Methionine-requiring protein 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314804|imex:IM-14275-83 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YJR010W(gene)|ensemblfungi:YJR010W_mRNA(transcript)|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0004781"("sulfate adenylyltransferase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0010134"(sulfate assimilation via adenylyl sulfate reduction)|go:"GO:0019379"("sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)")|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|interpro:IPR002650(ATP-sulphurylase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR015947(PUA-like)|interpro:IPR024951|interpro:IPR025980|interpro:IPR027417|interpro:IPR027535|rcsb pdb:1G8F|rcsb pdb:1G8G|rcsb pdb:1G8H|rcsb pdb:1J70|rcsb pdb:1JEC|rcsb pdb:1JED|rcsb pdb:1JEE|rcsb pdb:1R6X|sgd:S000003771|refseq:NP_012543.3|mint:P08536|dip:DIP-4303N ensemblfungi:YJR010W(gene)|ensemblfungi:YJR010W_mRNA(transcript)|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0004781"("sulfate adenylyltransferase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0010134"(sulfate assimilation via adenylyl sulfate reduction)|go:"GO:0019379"("sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)")|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|interpro:IPR002650(ATP-sulphurylase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR015947(PUA-like)|interpro:IPR024951|interpro:IPR025980|interpro:IPR027417|interpro:IPR027535|rcsb pdb:1G8F|rcsb pdb:1G8G|rcsb pdb:1G8H|rcsb pdb:1J70|rcsb pdb:1JEC|rcsb pdb:1JED|rcsb pdb:1JEE|rcsb pdb:1R6X|sgd:S000003771|refseq:NP_012543.3|mint:P08536|dip:DIP-4303N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rfd8JMKCcm7naEJMgEjXLaZBejM559292 rogid:rfd8JMKCcm7naEJMgEjXLaZBejM559292 intact-crc:14B05DCF45E3FA58|rigid:wZKWOsS6IRoCLbgA6a2ZskOOUKw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08518 uniprotkb:Q06505 intact:EBI-15767|uniprotkb:Q12738|uniprotkb:Q7Z9Y0|uniprotkb:D6W2K8|ensemblfungi:YOR151C intact:EBI-32596|uniprotkb:D6W4C9|ensemblfungi:YPR133C psi-mi:rpb2_yeast(display_long)|uniprotkb:YOR151C(locus name)|uniprotkb:RPB2(gene name)|psi-mi:RPB2(display_short)|uniprotkb:RPB150(gene name synonym)|uniprotkb:RPO22(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym)|uniprotkb:B150(gene name synonym) psi-mi:iws1_yeast(display_long)|uniprotkb:SPN1(gene name)|psi-mi:SPN1(display_short)|uniprotkb:Interacts with SPT6 protein 1(gene name synonym)|uniprotkb:Suppresses postrecruitment functions protein 1(gene name synonym)|uniprotkb:IWS1(gene name synonym)|uniprotkb:YPR133C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314793|imex:IM-14275-82 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005677|refseq:NP_014794.3|dip:DIP-14N|mint:P08518|ensemblfungi:YOR151C(gene)|ensemblfungi:YOR151C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519 refseq:NP_015458.1|sgd:S000006337|dip:DIP-3823N|mint:Q06505|ensemblfungi:YPR133C(gene)|ensemblfungi:YPR133C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070827"(obsolete chromatin maintenance)|interpro:IPR017923|interpro:IPR035441|rcsb pdb:3NFQ|rcsb pdb:3O8Z|rcsb pdb:3OAK|reactome:R-SCE-674695|reactome:R-SCE-75955 psi-mi:"MI:0469"(intact) crc64:BABD03212C0A583E crc64:7BC925FC8BA80E65 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:OtaUDREazRORKDcfBajDLPlXovY559292 rogid:ZGGEVh+io3MVCEa9lu5qnfaJURA559292 intact-crc:B8B0BBD5230E3813|rigid:Jc++3Z182Oxnm/SDJWlqf5JBlOE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08518 uniprotkb:P20434 intact:EBI-15767|uniprotkb:Q12738|uniprotkb:Q7Z9Y0|uniprotkb:D6W2K8|ensemblfungi:YOR151C intact:EBI-15781|uniprotkb:Q02121|ensemblfungi:YBR154C|uniprotkb:D6VQE9 psi-mi:rpb2_yeast(display_long)|uniprotkb:YOR151C(locus name)|uniprotkb:RPB2(gene name)|psi-mi:RPB2(display_short)|uniprotkb:RPB150(gene name synonym)|uniprotkb:RPO22(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym)|uniprotkb:B150(gene name synonym) psi-mi:rpab1_yeast(display_long)|uniprotkb:RPB5(gene name)|psi-mi:RPB5(display_short)|uniprotkb:YBR154C(locus name)|uniprotkb:YBR1204(orf name)|uniprotkb:RPA7(gene name synonym)|uniprotkb:RPC9(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide(gene name synonym)|uniprotkb:ABC27(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314782|imex:IM-14275-81 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005677|refseq:NP_014794.3|dip:DIP-14N|mint:P08518|ensemblfungi:YOR151C(gene)|ensemblfungi:YOR151C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519 rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|rcsb pdb:1WCM|rcsb pdb:1Y1V|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|rcsb pdb:2B63|rcsb pdb:2B8K|interpro:IPR020608|interpro:IPR020609|rcsb pdb:2E2H|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:1DZF|rcsb pdb:1I3Q|rcsb pdb:2E2I|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:5M5Y|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6H67|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:2E2J|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|ensemblfungi:YBR154C(gene)|ensemblfungi:YBR154C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4V1M|rcsb pdb:2JA5|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2JA6|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:2JA7|rcsb pdb:3GTG|rcsb pdb:2JA8|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:2NVQ|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4YM7|rcsb pdb:5C3E|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5G5L|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6H68|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|rcsb pdb:6UQ2|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-77075|reactome:R-SCE-9018519|refseq:NP_009712.1|sgd:S000000358|dip:DIP-71N|mint:P20434 psi-mi:"MI:0469"(intact) crc64:BABD03212C0A583E crc64:2A15F7114D69D829 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:OtaUDREazRORKDcfBajDLPlXovY559292 rogid:j/jAJ2fXWf4ebK1aWTWrKERGUpM559292 intact-crc:BA74E05B1FA524CA|rigid:xa2Gr4shEu2Zhz8R+eQ14QvLlr8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08518 uniprotkb:P07286 intact:EBI-15767|uniprotkb:Q12738|uniprotkb:Q7Z9Y0|uniprotkb:D6W2K8|ensemblfungi:YOR151C intact:EBI-7852|uniprotkb:D6VQN9|ensemblfungi:YBR243C psi-mi:rpb2_yeast(display_long)|uniprotkb:YOR151C(locus name)|uniprotkb:RPB2(gene name)|psi-mi:RPB2(display_short)|uniprotkb:RPB150(gene name synonym)|uniprotkb:RPO22(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym)|uniprotkb:B150(gene name synonym) psi-mi:gpt_yeast(display_long)|uniprotkb:TUR1(gene name synonym)|uniprotkb:YBR1628(orf name)|uniprotkb:YBR243C(locus name)|uniprotkb:ALG7(gene name)|psi-mi:ALG7(display_short)|uniprotkb:N-acetylglucosamine-1-phosphate transferase(gene name synonym)|uniprotkb:GlcNAc-1-P transferase(gene name synonym)|uniprotkb:Tunicamycin resistance protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314771|imex:IM-14275-80 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005677|refseq:NP_014794.3|dip:DIP-14N|mint:P08518|ensemblfungi:YOR151C(gene)|ensemblfungi:YOR151C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519 sgd:S000000447|refseq:NP_009802.3|dip:DIP-5364N|mint:P07286|ensemblfungi:YBR243C(gene)|ensemblfungi:YBR243C_mRNA(transcript)|go:"GO:0003975"(UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006489"(dolichyl diphosphate biosynthetic process)|go:"GO:0008963"(phospho-N-acetylmuramoyl-pentapeptide-transferase activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0043541"(UDP-N-acetylglucosamine transferase complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR000715(Glycosyl transferase, family 4)|interpro:IPR033895|reactome:R-SCE-446193 psi-mi:"MI:0469"(intact) crc64:BABD03212C0A583E - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:OtaUDREazRORKDcfBajDLPlXovY559292 rogid:nwAb0WMTgVU4LoAGHFxOjCYe1ok559292 intact-crc:47B8662BCC6D5FE8|rigid:dTEy2W3fwGT/U/WRNWuTNp3U7XI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:P09620 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314848|imex:IM-14275-87 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:9D9B23FE903B68E6|rigid:mkyxT9LczASMPGuu9IW0q9ctVTE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09435 uniprotkb:P15496 intact:EBI-8611|uniprotkb:P18862|uniprotkb:D6VPS7|ensemblfungi:YBL075C intact:EBI-8902|ensemblfungi:YPL117C|uniprotkb:D6W3Q1 psi-mi:hsp73_yeast(display_long)|uniprotkb:YBL06.07(orf name)|uniprotkb:YBL0610(orf name)|uniprotkb:YBL075C(locus name)|uniprotkb:SSA3(gene name)|psi-mi:SSA3(display_short) psi-mi:idi1_yeast(display_long)|uniprotkb:Isopentenyl pyrophosphate isomerase(gene name synonym)|uniprotkb:IDI1(gene name)|psi-mi:IDI1(display_short)|uniprotkb:BOT2(gene name synonym)|uniprotkb:YPL117C(locus name)|uniprotkb:LPH10C(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314837|imex:IM-14275-86 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009478.1|sgd:S000000171|mint:P09435|dip:DIP-2266N|ensemblfungi:YBL075C(gene)|ensemblfungi:YBL075C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129 ensemblfungi:YPL117C(gene)|ensemblfungi:YPL117C_mRNA(transcript)|go:"GO:0004452"(isopentenyl-diphosphate delta-isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009240"(isopentenyl diphosphate biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0045337"(farnesyl diphosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050992"(dimethylallyl diphosphate biosynthetic process)|reactome:R-SCE-191273|refseq:NP_015208.1|sgd:S000006038|interpro:IPR011876(Isopentenyl-diphosphate delta-isomerase, type 1)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|mint:P15496 psi-mi:"MI:0469"(intact) crc64:F4B136759B7D4636 - figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:u3ayjvFHnVNMMrDZdrB7NWaGzBg559292 rogid:KQ9qSb2grQ4DQip7atYPeCwp5QM559292 intact-crc:0EE517D83F58005B|rigid:3xxmN03mvG4dbEeaza/BFSMcdYs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08679 uniprotkb:P08679 intact:EBI-4713|uniprotkb:D6VR15|ensemblfungi:YCR005C intact:EBI-4713|uniprotkb:D6VR15|ensemblfungi:YCR005C psi-mi:cisy2_yeast(display_long)|uniprotkb:CIT2(gene name)|psi-mi:CIT2(display_short)|uniprotkb:YCR043(orf name)|uniprotkb:YCR5C(orf name)|uniprotkb:YCR005C(locus name) psi-mi:cisy2_yeast(display_long)|uniprotkb:CIT2(gene name)|psi-mi:CIT2(display_short)|uniprotkb:YCR043(orf name)|uniprotkb:YCR5C(orf name)|uniprotkb:YCR005C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314826|imex:IM-14275-85 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009931.1|sgd:S000000598|dip:DIP-1259N|mint:P08679|ensemblfungi:YCR005C(gene)|ensemblfungi:YCR005C_mRNA(transcript)|go:"GO:0004108"("citrate (Si)-synthase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR010109(Citrate synthase, eukaryotic)|interpro:IPR016142(Citrate synthase-like, large alpha subdomain)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR019810|interpro:IPR036969 refseq:NP_009931.1|sgd:S000000598|dip:DIP-1259N|mint:P08679|ensemblfungi:YCR005C(gene)|ensemblfungi:YCR005C_mRNA(transcript)|go:"GO:0004108"("citrate (Si)-synthase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR010109(Citrate synthase, eukaryotic)|interpro:IPR016142(Citrate synthase-like, large alpha subdomain)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR019810|interpro:IPR036969 psi-mi:"MI:0469"(intact) crc64:AB2F66AD9A9399EF crc64:AB2F66AD9A9399EF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:/SK9j3zetaFxY17yqb9qFbRW4K0559292 rogid:/SK9j3zetaFxY17yqb9qFbRW4K0559292 intact-crc:526F92D1DD290601|rigid:bNFiU146qXjXpnaNCThQnWOYfbs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23585 uniprotkb:P09620 intact:EBI-2054100|uniprotkb:D6VZI5|ensemblfungi:YMR011W intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:hxt2_yeast(display_long)|uniprotkb:YM8270.15(orf name)|uniprotkb:YMR011W(locus name)|uniprotkb:HXT2(gene name)|psi-mi:HXT2(display_short) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314903|imex:IM-14275-92 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013724.1|sgd:S000004613|dip:DIP-7912N|mint:P23585|ensemblfungi:YMR011W(gene)|ensemblfungi:YMR011W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:d4PFyh6BHnB/WnnF3A4GF3EphgY559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:242C0824472D009B|rigid:Lb0sn3bky3vvrQkWP9H9q9zvoGc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:P09620 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314892|imex:IM-14275-91 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:D989E31519E1E349|rigid:drEUEqGPRBtmd6LlLWXjdHpF/TE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:P13134 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5 psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314881|imex:IM-14275-90 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134 psi-mi:"MI:0469"(intact) - crc64:5DCEEDADCF439C78 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292 intact-crc:DDFDBF51F5CB6A64|rigid:zpFwRxBiJoUGwWihoIcTv+g+VZA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:P11076 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314870|imex:IM-14275-89 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 psi-mi:"MI:0469"(intact) - crc64:796859026AC63CC0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 intact-crc:D7DEB0375F846E0B|rigid:uK8ggexJwrl+0+QZZ39eir38WFc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11075 uniprotkb:P09620 intact:EBI-16882|uniprotkb:Q03960|uniprotkb:Q04139|uniprotkb:D6VSF1|ensemblfungi:YDR170C intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:sec7_yeast(display_long)|uniprotkb:SEC7(gene name)|psi-mi:SEC7(display_short)|uniprotkb:YD9395.01C(orf name)|uniprotkb:YD9489.05C(orf name)|uniprotkb:YDR170C(locus name) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314859|imex:IM-14275-88 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010454.3|ensemblfungi:YDR170C(gene)|ensemblfungi:YDR170C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005770"(late endosome)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0032012"(regulation of ARF protein signal transduction)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|rcsb pdb:4OIY|go:"GO:0015031"(protein transport)|sgd:S000002577|dip:DIP-830N|mint:P11075 ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) crc64:02B2D370DD2E4661 - figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BoKfHXfAHnYKyYGbglgZr/3djRw559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:C711BE3D31988CF6|rigid:wNdgxqwxV3cJuwaXEe4PemNDjdE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25656 uniprotkb:P09620 intact:EBI-22014|uniprotkb:D6VR94|ensemblfungi:YCR094W intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:cdc50_yeast(display_long)|uniprotkb:YCR94W(orf name)|uniprotkb:YCR094W(locus name)|uniprotkb:CDC50(gene name)|psi-mi:CDC50(display_short) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314914|imex:IM-14275-93 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010018.1|sgd:S000000690|dip:DIP-5138N|ensemblfungi:YCR094W(gene)|ensemblfungi:YCR094W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0140331"(aminophospholipid translocation)|go:"GO:1990530"(Cdc50p-Drs2p complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|rcsb pdb:6PSY|rcsb pdb:6ROH|rcsb pdb:6ROI|rcsb pdb:6ROJ|rcsb pdb:7OH4|rcsb pdb:7OH6|rcsb pdb:7OH7|reactome:R-SCE-6798695|rcsb pdb:6PSX|mint:P25656 ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) crc64:565575CA402C0C91 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zVi09MNh1hpBUuc5AzasxmCrnKY559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:7A4B873A2DFCDF73|rigid:tJ84hUpalGryubX8erKHEKImulE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30605 uniprotkb:P09620 intact:EBI-2050956|uniprotkb:D6VTB9|ensemblfungi:YDR497C intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:itr1_yeast(display_long)|uniprotkb:D9719.3(orf name)|uniprotkb:YDR497C(locus name)|uniprotkb:ITR1(gene name)|psi-mi:ITR1(display_short) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314936|imex:IM-14275-95 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010785.1|sgd:S000002905|dip:DIP-7406N|mint:P30605|ensemblfungi:YDR497C(gene)|ensemblfungi:YDR497C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GgtK4YFe7ZCZcmVpV5q1KY2F0Ds559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:6E0C6C07FFCCAD3D|rigid:Ka+r4hmQRHi80S94tcJcihUigRw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29465 uniprotkb:P09620 intact:EBI-4632|uniprotkb:D6VQ25|ensemblfungi:YBR023C intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:chs3_yeast(display_long)|uniprotkb:CHS3(gene name)|psi-mi:CHS3(display_short)|uniprotkb:CAL1(gene name synonym)|uniprotkb:DIT101(gene name synonym)|uniprotkb:KIT2(gene name synonym)|uniprotkb:YBR023C(locus name)|uniprotkb:CSD2(gene name synonym)|uniprotkb:YBR0305(orf name)|uniprotkb:Chitin-UDP acetyl-glucosaminyl transferase 3(gene name synonym)|uniprotkb:Class-IV chitin synthase 3(gene name synonym) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314925|imex:IM-14275-94 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009579.1|sgd:S000000227|dip:DIP-2482N|mint:P29465|ensemblfungi:YBR023C(gene)|ensemblfungi:YBR023C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0004100"(chitin synthase activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030428"(cell septum)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0045009"(chitosome)|go:"GO:0071944"(cell periphery)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR004835(Fungal chitin synthase)|interpro:IPR029044|rcsb pdb:4WJW ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8Ik0u35UXSJVtqfgNdo49J+nzFk559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:44C521BC13B7C33C|rigid:b3oT45ulsrVCMM91DPjKK+C4BPI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:P09620 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314958|imex:IM-14275-97 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:8811E7F04F4A935B|rigid:TvgyNfdZzsgIFQhB0A3OSEUg5Gw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32319 uniprotkb:P09620 intact:EBI-13123|uniprotkb:D6VPY3|ensemblfungi:YBL017C intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:vps10_yeast(display_long)|uniprotkb:PEP1(gene name)|psi-mi:PEP1(display_short)|uniprotkb:Vacuolar carboxypeptidase sorting receptor VPS10(gene name synonym)|uniprotkb:Carboxypeptidase Y receptor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 1(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 1(gene name synonym)|uniprotkb:Sortilin VPS10(gene name synonym)|uniprotkb:VPS10(gene name synonym)|uniprotkb:VPT1(gene name synonym)|uniprotkb:YBL03.22(orf name)|uniprotkb:YBL0302(orf name)|uniprotkb:YBL017C(locus name) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314947|imex:IM-14275-96 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009536.1|sgd:S000000113|mint:P32319|dip:DIP-5900N|ensemblfungi:YBL017C(gene)|ensemblfungi:YBL017C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000423"(mitophagy)|go:"GO:0000425"(pexophagy)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048203"(vesicle targeting, trans-Golgi to endosome)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR036278 ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) crc64:C778A0400612ECF4 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dYYsekAaDw4SzmEUSe5tYb5a43M559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:E115234734322CF9|rigid:d8RpvqhxyqRvPiWgeFIBgiIb9ro false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:P36164 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-26527|uniprotkb:D6VXE8|ensemblfungi:YKR088C psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:tvp38_yeast(display_long)|uniprotkb:YKR408(orf name)|uniprotkb:YKR088C(locus name)|uniprotkb:TVP38(gene name)|psi-mi:TVP38(display_short)|uniprotkb:TLG2-vesicle protein of 38 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314991|imex:IM-14275-100 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 sgd:S000001796|refseq:NP_013014.3|mint:P36164|dip:DIP-5167N|interpro:IPR032816|ensemblfungi:YKR088C(gene)|ensemblfungi:YKR088C_mRNA(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0005737"(cytoplasm)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane) psi-mi:"MI:0469"(intact) - crc64:7EA95DD4E5AF77FE figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:wNtRh3eKqVkQKwO9QmrJHjSSdnk559292 intact-crc:8B4C0B95A92CE7BD|rigid:HO+x7VpoJc66xeGcMaY49aGSTdw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33413 uniprotkb:P09620 intact:EBI-2060312|uniprotkb:D3DKP5|ensemblfungi:YHL016C intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:dur3_yeast(display_long)|uniprotkb:DUR3(gene name)|psi-mi:DUR3(display_short)|uniprotkb:YHL016C(locus name) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314980|imex:IM-14275-99 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031155|refseq:NP_011847.1|sgd:S000001008|interpro:IPR001734(Na+/solute symporter)|interpro:IPR038377|mint:P33413|ensemblfungi:YHL016C(gene)|ensemblfungi:YHL016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0015204"(urea transmembrane transporter activity)|go:"GO:0015489"(putrescine transmembrane transporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015840"(urea transport)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oTFsdtOngA3q5wCbhK/fpVlIsz0559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:D0AA902AD881BD1F|rigid:4N8kpqRtD4GI6bmI7D+TPnZONG8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32660 uniprotkb:P09620 intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6314969|imex:IM-14275-98 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) crc64:3CC3FBA8ADDE8960 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:47EE7F3CEB23FFB4|rigid:Cn/fnFIQqoev3I3Wv2u6k1aKhqU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39111 uniprotkb:P09620 intact:EBI-20272|uniprotkb:D6VUF5|ensemblfungi:YGR020C intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:vatf_yeast(display_long)|uniprotkb:VMA7(gene name)|psi-mi:VMA7(display_short)|uniprotkb:YGR020C(locus name)|uniprotkb:Vacuolar proton pump subunit F(gene name synonym)|uniprotkb:V-ATPase 14 kDa subunit(gene name synonym) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315035|imex:IM-14275-104 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011534.1|sgd:S000003252|ensemblfungi:YGR020C(gene)|ensemblfungi:YGR020C_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016020"(membrane)|go:"GO:0042625"(ATPase-coupled ion transmembrane transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005772(ATPase, V1 complex, subunit F, eukaryotic)|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|interpro:IPR036906|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4IX9|rcsb pdb:4RND|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2077N|mint:P39111 ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) crc64:D21EC0980EB99DFF - figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VtthQl2jj9fpjv3psX0YUNbIAKU559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:0F488F790E98CEF7|rigid:abasQDcdEPk6sKT1xBidmDNgGJc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39010 uniprotkb:P09620 intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315024|imex:IM-14275-103 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:EFACE886204AB557|rigid:r4jVTouQUEp3nkkER8F1zT1D3nA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:P38932 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-20444|uniprotkb:D6VU50|ensemblfungi:YGL095C psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:vps45_yeast(display_long)|uniprotkb:VPS45(gene name)|psi-mi:VPS45(display_short)|uniprotkb:STT10(gene name synonym)|uniprotkb:VPL28(gene name synonym)|uniprotkb:YGL095C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315013|imex:IM-14275-102 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 sgd:S000003063|refseq:NP_011420.3|ensemblfungi:YGL095C(gene)|ensemblfungi:YGL095C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007033"(vacuole organization)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0035543"(positive regulation of SNARE complex assembly)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|reactome:R-SCE-983231|dip:DIP-2693N|mint:P38932 psi-mi:"MI:0469"(intact) - crc64:4AA50D568228228F figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:HSNdSBz2AD5AS/nSUjPV02ym8HQ559292 intact-crc:F8020D22CCF5CD31|rigid:6X58862wfAn9zuHa6zFwiuTgsCg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38310 uniprotkb:P09620 intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315002|imex:IM-14275-101 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) crc64:7B4E620ABC39A053 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:F1E05912842BFD6E|rigid:CKJONO0KxowDr1BG6Bs/wolfQ8A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:P41810 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-4869|uniprotkb:Q03779|uniprotkb:D6VSL9|ensemblfungi:YDR238C psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:copb_yeast(display_long)|uniprotkb:SEC26(gene name)|psi-mi:SEC26(display_short)|uniprotkb:YDR238C(locus name)|uniprotkb:YD8419.05C(orf name)|uniprotkb:Beta-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315079|imex:IM-14275-108 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 sgd:S000002646|refseq:NP_010524.3|dip:DIP-6467N|mint:P41810|ensemblfungi:YDR238C(gene)|ensemblfungi:YDR238C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|reactome:R-SCE-6798695|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - crc64:885420DB026BCFA3 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:ZfLp1BUmvVuTiXn7/Zbf/3m6VtE559292 intact-crc:0D52A3052F0D9A28|rigid:dEtp5AASJAl1rGvDvNFSM/PEb5Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:P40335 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-20373|uniprotkb:D6VWC9|intact:EBI-3674163|uniprotkb:E9P910|ensemblfungi:YJL053W psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:pep8_yeast(display_long)|uniprotkb:PEP8(gene name)|psi-mi:PEP8(display_short)|uniprotkb:GRD6(gene name synonym)|uniprotkb:VPS26(gene name synonym)|uniprotkb:VPT4(gene name synonym)|uniprotkb:J1152(orf name)|uniprotkb:YJL053W(locus name)|uniprotkb:Vacuolar protein-targeting protein 4(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 26(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315068|imex:IM-14275-107 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 refseq:NP_012482.1|sgd:S000003589|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0140318"(protein transporter activity)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR028934|reactome:R-SCE-3238698|ensemblfungi:YJL053W(gene)|ensemblfungi:YJL053W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|dip:DIP-4572N|mint:P40335 psi-mi:"MI:0469"(intact) - crc64:40D15594E70A9B58 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:mwZb20cO8nZl8hVUSRXAB5Varg0559292 intact-crc:5A76BAF12C333208|rigid:xG1CFXb2tZ7b1fBAmDzBKPTxhj0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39719 uniprotkb:P09620 intact:EBI-20703|uniprotkb:Q05165|uniprotkb:D6VPG5|ensemblfungi:YAL053W intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:flc2_yeast(display_long)|uniprotkb:YAL053W(locus name)|uniprotkb:FLC2(gene name)|psi-mi:FLC2(display_short)|uniprotkb:FAD transporter 2(gene name synonym)|uniprotkb:TRP-like ion channel FLC2(gene name synonym) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315057|imex:IM-14275-106 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009348.2|sgd:S000000049|ensemblfungi:YAL053W(gene)|ensemblfungi:YAL053W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241|go:"GO:0055085"(transmembrane transport)|dip:DIP-6708N|mint:P39719 ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:NOmMW54DNa0o7vM945DlZgVUy44559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:516F37DE1BEEE069|rigid:9q0DzukPvfP5DWKCZpWSRy7+0WU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:P39524 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-3106|uniprotkb:D6VPJ2|ensemblfungi:YAL026C psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:atc3_yeast(display_long)|uniprotkb:DRS2(gene name)|psi-mi:DRS2(display_short)|uniprotkb:FUN38(orf name)|uniprotkb:YAL026C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315046|imex:IM-14275-105 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 refseq:NP_009376.2|sgd:S000000024|dip:DIP-2216N|mint:P39524|ensemblfungi:YAL026C(gene)|ensemblfungi:YAL026C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|go:"GO:1990530"(Cdc50p-Drs2p complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:6PSX|rcsb pdb:6PSY|rcsb pdb:6ROH|rcsb pdb:6ROI|rcsb pdb:6ROJ|rcsb pdb:7OH4|rcsb pdb:7OH5|rcsb pdb:7OH6|rcsb pdb:7OH7|reactome:R-SCE-6798695|reactome:R-SCE-936837 psi-mi:"MI:0469"(intact) - crc64:5745B92901F8E1AE figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:qJ8uK7dznIqyjVwjbw/VGn5Bo+4559292 intact-crc:E0BC2C8EFA4B62C3|rigid:eONXk4QrZWXTbDz3gGNwUuGCdjI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:P53959 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-4829|uniprotkb:D6W1D8|ensemblfungi:YNL041C psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:cog6_yeast(display_long)|uniprotkb:COG6(gene name)|psi-mi:COG6(display_short)|uniprotkb:COD2(gene name synonym)|uniprotkb:TFI2(gene name synonym)|uniprotkb:YNL041C(locus name)|uniprotkb:N2675(orf name)|uniprotkb:SEC37(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 6(gene name synonym)|uniprotkb:Complexed with DOR1 protein 2(gene name synonym)|uniprotkb:Protein SEC37(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315123|imex:IM-14275-112 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 refseq:NP_014357.1|sgd:S000004986|dip:DIP-4373N|mint:P53959|ensemblfungi:YNL041C(gene)|ensemblfungi:YNL041C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|interpro:IPR010490(Conserved oligomeric complex COG6) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:PF6acMk/xEQAGjElIukh7JGI46Y559292 intact-crc:CB9D55B99B45853B|rigid:ulsLFqNHKpu3mb6V7x4tFNmskkM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P09620 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315112|imex:IM-14275-111 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:717DA35F8E272F5E|rigid:IgKGPW1yMfOMQymI6es82qFyUt4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:P43621 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-4876|uniprotkb:D6VTT4|ensemblfungi:YFR051C psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:copd_yeast(display_long)|uniprotkb:RET2(gene name)|psi-mi:RET2(display_short)|uniprotkb:YFR051C(locus name)|uniprotkb:Delta-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315101|imex:IM-14275-110 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 sgd:S000001947|refseq:NP_116709.3|dip:DIP-5255N|mint:P43621|ensemblfungi:YFR051C(gene)|ensemblfungi:YFR051C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|rcsb pdb:5FJW|rcsb pdb:5FJX|rcsb pdb:5FJZ|rcsb pdb:5FK0|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - crc64:AA730F046655EE5A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:auvjuT8ffm1R4P3mRKEIWAsynW0559292 intact-crc:A718FDDF7164674E|rigid:g2bSxIClg3Gn0e+evtH0YZS8700 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:P41811 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315090|imex:IM-14275-109 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - crc64:6A5E50BBEB02CB58 figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:92ECDB430AF9C47C|rigid:qdKSCJadAmYTVu+b4LLSArCed6A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05521 uniprotkb:P09620 intact:EBI-2054360|uniprotkb:D6VSR4|ensemblfungi:YDR284C intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:dpp1_yeast(display_long)|uniprotkb:ZRG1(gene name synonym)|uniprotkb:Phosphatidate phosphatase(gene name synonym)|uniprotkb:YDR284C(locus name)|uniprotkb:DPP1(gene name)|psi-mi:DPP1(display_short)|uniprotkb:Lysophosphatidate phosphatase(gene name synonym) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315167|imex:IM-14275-116 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010570.1|sgd:S000002692|dip:DIP-8807N|mint:Q05521|ensemblfungi:YDR284C(gene)|ensemblfungi:YDR284C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000810"(diacylglycerol diphosphate phosphatase activity)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042577"(lipid phosphatase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR043216|reactome:R-SCE-1660661|reactome:R-SCE-2029485|reactome:R-SCE-419408 ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Hj9zgQNj43XlykGFSKPcXJ28Lqg559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:F347EAFFD58F481D|rigid:rnkA7kv2NKi0Egvx04BeB0+vYvA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03860 uniprotkb:P09620 intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315156|imex:IM-14275-115 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) crc64:395F700FBB14C569 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:909D3C7180598E6B|rigid:5/nljQ0tKADopmvNsn/GHnC3UwM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:Q03687 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315145|imex:IM-14275-114 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 intact-crc:7AE36FBEFF827D69|rigid:6xKme0rsdctmusedKjQ1Y4YQSCI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02785 uniprotkb:P09620 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315134|imex:IM-14275-113 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:157F77140647C211|rigid:Kpnj7l0bkFHY9tKypXpE7HFXjEc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08280 uniprotkb:P09620 intact:EBI-35858|uniprotkb:Q6B229|uniprotkb:D6W1T2|ensemblfungi:YOL137W intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:bsc6_yeast(display_long)|uniprotkb:YOL137W(locus name)|uniprotkb:BSC6(gene name)|psi-mi:BSC6(display_short) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315200|imex:IM-14275-119 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014504.1|sgd:S000005497|mint:Q08280|dip:DIP-4683N|ensemblfungi:YOL137W(gene)|ensemblfungi:YOL137W_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WVYZke8YJvNcS4D9bUnthAFdq3A559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:74BE6AD529932A57|rigid:TUDQePGXGteL8BlY8LBlMkiafnE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06810 uniprotkb:P09620 intact:EBI-2068557|uniprotkb:D6W479|uniprotkb:Q6B149|ensemblfungi:YPR075C intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:opy2_yeast(display_long)|uniprotkb:OPY2(gene name)|psi-mi:OPY2(display_short)|uniprotkb:Overproduction-induced pheromone-resistant protein 2(gene name synonym)|uniprotkb:YPR075C(locus name) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315189|imex:IM-14275-118 author score:99.34 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015400.1|sgd:S000006279|interpro:IPR018571|mint:Q06810|ensemblfungi:YPR075C(gene)|ensemblfungi:YPR075C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000751"(mitotic cell cycle G1 arrest in response to pheromone)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.34|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:avNmi6o7WtIkxIyUvhoboBXL8sc559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:4747C5B12F87FD42|rigid:S7stOgI5QnmOYP31AFi5slUa9Vg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06689 uniprotkb:P09620 intact:EBI-38659|uniprotkb:D6VZ50|ensemblfungi:YLR413W intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:yl413_yeast(display_long)|uniprotkb:YLR413W(locus name) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315178|imex:IM-14275-117 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013517.1|sgd:S000004405|mint:Q06689|dip:DIP-5075N|ensemblfungi:YLR413W(gene)|ensemblfungi:YLR413W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0071944"(cell periphery)|interpro:IPR009571(SUR7) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) crc64:92E23436DC857E95 - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AoTGKjLhw0NECrtuftZqLANonds559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:87FEAAAA513EF486|rigid:t0TWsFUFM/x+a1ORlF4sFNvtjm0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:Q12114 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-4640|uniprotkb:D6VYX2|ensemblfungi:YLR330W psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:chs5_yeast(display_long)|uniprotkb:CHS5(gene name)|psi-mi:CHS5(display_short)|uniprotkb:CAL3(gene name synonym)|uniprotkb:YLR330W(locus name)|uniprotkb:L8543.18(orf name)|uniprotkb:Protein CAL3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315233|imex:IM-14275-122 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 refseq:NP_013434.1|sgd:S000004322|dip:DIP-8073N|mint:Q12114|ensemblfungi:YLR330W(gene)|ensemblfungi:YLR330W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006039"(cell wall chitin catabolic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034044"(exomer complex)|go:"GO:0043332"(mating projection tip)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001357(BRCT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031669|interpro:IPR031673|interpro:IPR036116|interpro:IPR036420|rcsb pdb:4IN3|rcsb pdb:4WJW|rcsb pdb:4YG8 psi-mi:"MI:0469"(intact) - crc64:FA92741B862814C2 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:iHvfW3fNLv3HLj4Ihya1Vyt0X7I559292 intact-crc:936C73A751D41DF6|rigid:O7sRg3FZ55zrJQ/FEKB5PWtueW4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:Q12057 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-29838|uniprotkb:D6W2G4|ensemblfungi:YOR104W psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:pin2_yeast(display_long)|uniprotkb:PIN2(gene name)|psi-mi:PIN2(display_short)|uniprotkb:YOR3214W(orf name)|uniprotkb:YOR104W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315222|imex:IM-14275-121 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 sgd:S000005630|refseq:NP_014747.1|dip:DIP-4459N|mint:Q12057|ensemblfungi:YOR104W(gene)|ensemblfungi:YOR104W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|interpro:IPR037504 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:Zk6iUcpP++MEXuhKZ79TMOYQYqM559292 intact-crc:8988D558AC790B86|rigid:xPcY3oZxhQD1FTU6jwp3rmlF4lY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:Q08967 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-36673|uniprotkb:D6W3E9|ensemblfungi:YPL221W psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:flc1_yeast(display_long)|uniprotkb:FAD transporter 1(gene name synonym)|uniprotkb:FLC1(gene name)|psi-mi:FLC1(display_short)|uniprotkb:TRP-like ion channel protein FLC1(gene name synonym)|uniprotkb:Heme utilization factor 1(gene name synonym)|uniprotkb:Bypass of PAM1 protein 1(gene name synonym)|uniprotkb:HUF1(gene name synonym)|uniprotkb:YPL221W(locus name)|uniprotkb:BOP1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315211|imex:IM-14275-120 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 refseq:NP_015103.1|sgd:S000006142|mint:Q08967|dip:DIP-3965N|ensemblfungi:YPL221W(gene)|ensemblfungi:YPL221W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055085"(transmembrane transport)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:r6CcZGEjxHUk2w0iBUBvnAPaFd4559292 intact-crc:ACD82B2771F66B70|rigid:v8FioQ/YNQ/t703wMzBE2B4Gr9A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CX15 uniprotkb:P53131 intact:EBI-6315275|ensemblfungi:YGR296W|ensemblfungi:YPL283C|uniprotkb:D6VV70|uniprotkb:P53345|uniprotkb:Q9UQW1 intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 psi-mi:yrf17_yeast(display_long)|uniprotkb:YRF1-7(gene name)|psi-mi:YRF1-7(display_short)|uniprotkb:YPL283C(locus name) psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315270|imex:IM-14275-125 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR296W(gene)|ensemblfungi:YGR296W_mRNA(transcript)|ensemblfungi:YPL283C(gene)|ensemblfungi:YPL283C_mRNA(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR021646|mint:P0CX15|interpro:IPR014001(DEAD-like helicase, N-terminal)|refseq:NP_015040.1|sgd:S000006204|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|refseq:NP_011812.3|interpro:IPR027417|interpro:IPR037240 go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131 psi-mi:"MI:0469"(intact) caution:This sequence has been withdrawn from Uniprot.|crc64:65B3C19E1BFD40D7 crc64:DA8A085EC50FF430 figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ng7D47DFNV7q78gztQTtEB9rksI559292 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 intact-crc:F12592F67D4260BE|rigid:Nhjomro55bVFGNs2gleq498ntco false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CX10 uniprotkb:P53939 intact:EBI-6315262|ensemblfungi:YOR393W|ensemblfungi:YPL281C|uniprotkb:D6W385|uniprotkb:Q12007|uniprotkb:Q7LGJ4 intact:EBI-28760|uniprotkb:D6W1A1|ensemblfungi:YNL078W psi-mi:err1_yeast(display_long)|uniprotkb:ERR1(gene name)|psi-mi:ERR1(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:2-phosphoglycerate dehydratase(gene name synonym)|uniprotkb:YOR393W(locus name) psi-mi:nis1_yeast(display_long)|uniprotkb:YNL078W(locus name)|uniprotkb:N2337(orf name)|uniprotkb:NIS1(gene name)|psi-mi:NIS1(display_short)|uniprotkb:JIP1(gene name synonym)|uniprotkb:Neck protein interacting with septins protein 1(gene name synonym)|uniprotkb:Jumonji domain-interacting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315257|imex:IM-14275-124 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR393W(gene)|ensemblfungi:YOR393W_mRNA(transcript)|ensemblfungi:YPL281C(gene)|ensemblfungi:YPL281C_mRNA(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0006096"(glycolytic process)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|reactome:R-SCE-70171|reactome:R-SCE-70263|mint:P0CX10|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|refseq:NP_015038.1|refseq:NP_015042.1|sgd:S000005920|interpro:IPR029017|interpro:IPR036849 sgd:S000005022|refseq:NP_014321.3|dip:DIP-1980N|mint:P53939|ensemblfungi:YNL078W(gene)|ensemblfungi:YNL078W_mRNA(transcript)|go:"GO:0005621"(cellular bud scar)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007120"(axial cellular bud site selection)|go:"GO:0032153"(cell division site)|go:"GO:0032174"(cellular bud neck septin collar)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0140014"(mitotic nuclear division) psi-mi:"MI:0469"(intact) - crc64:925C7B6063BCE4F1 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Vusa5LQZe98ke/mcTRdEnXReZDc559292 rogid:F2fY9SQ5kwYH8CZA8vGMZzwRiEM559292 intact-crc:836DC7A9434E44F1|rigid:cRnXUXGcdYqB3mwgpC2Ti7CC5Bg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CF34 uniprotkb:P25847 intact:EBI-6315249|uniprotkb:P14771|uniprotkb:Q12037|uniprotkb:Q12065|uniprotkb:Q6B0T5|uniprotkb:Q6WV04 intact:EBI-11352|uniprotkb:Q12423|ensemblfungi:YOL090W|uniprotkb:D6W1X8 psi-mi:yl016_yeast(display_long)|uniprotkb:SDC25(gene name)|psi-mi:SDC25(display_short)|uniprotkb:SCD25(gene name synonym)|uniprotkb:L1309(orf name)|uniprotkb:YLL016W(locus name) psi-mi:msh2_yeast(display_long)|uniprotkb:MSH2(gene name)|psi-mi:MSH2(display_short)|uniprotkb:YOL090W(locus name)|uniprotkb:O0935(orf name)|uniprotkb:MutS protein homolog 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315244|imex:IM-14275-123 author score:97.40 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003939|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|mint:P0CF34|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR019804|interpro:IPR023578|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR036964 ensemblfungi:YOL090W(gene)|ensemblfungi:YOL090W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000735"(removal of nonhomologous ends)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0006312"(mitotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043111"(replication fork arrest)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR032642|interpro:IPR036187|interpro:IPR036678|reactome:R-SCE-5358565|reactome:R-SCE-5358606|go:"GO:0032300"(mismatch repair complex)|refseq:NP_014551.1|sgd:S000005450|mint:P25847|dip:DIP-2415N psi-mi:"MI:0469"(intact) - crc64:43FFD8A640138AE4 figure legend:tables S3 and S4|author-confidence:97.40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Z0iUWuKNbg9gY88+dLX+35aqfIU559292 rogid:PNwekSiaI58qR+dPZZQW5UNRJ+4559292 intact-crc:A7D0D401B5D65F95|rigid:JxB8KU87rzfGIKz/l6ejZpBBUw0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CX79 uniprotkb:P40965 intact:EBI-6315283|ensemblfungi:YLR155C|ensemblfungi:YLR157C|ensemblfungi:YLR158C|ensemblfungi:YLR160C|uniprotkb:D6VYF3|uniprotkb:P11163|uniprotkb:Q12268|uniprotkb:Q6Q5K8|uniprotkb:Q6Q5K9 intact:EBI-11371|ensemblfungi:YFL003C|uniprotkb:D6VTM6 psi-mi:asp24_yeast(display_long)|uniprotkb:ASP3-4(gene name)|psi-mi:ASP3-4(display_short)|uniprotkb:L-asparaginase II(gene name synonym)|uniprotkb:L-asparagine amidohydrolase II(gene name synonym)|uniprotkb:L9632.9(orf name)|uniprotkb:YLR160C(locus name) psi-mi:msh4_yeast(display_long)|uniprotkb:MSH4(gene name)|psi-mi:MSH4(display_short)|uniprotkb:YFL003C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315285|imex:IM-14275-126 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR155C(gene)|ensemblfungi:YLR155C_mRNA(transcript)|ensemblfungi:YLR157C(gene)|ensemblfungi:YLR157C_mRNA(transcript)|ensemblfungi:YLR158C(gene)|ensemblfungi:YLR158C_mRNA(transcript)|ensemblfungi:YLR160C(gene)|ensemblfungi:YLR160C_mRNA(transcript)|go:"GO:0004067"(asparaginase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006530"(asparagine catabolic process)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0030287"(cell wall-bounded periplasmic space)|go:"GO:0042597"(periplasmic space)|go:"GO:0071944"(cell periphery)|mint:P0CX79|interpro:IPR004550(L-asparaginase, type II)|interpro:IPR006034(Asparaginase/glutaminase)|interpro:IPR020827|refseq:NP_013256.1|refseq:NP_013258.1|refseq:NP_013259.1|refseq:NP_013261.1|sgd:S000004150|interpro:IPR027473|interpro:IPR027474|interpro:IPR027475|interpro:IPR036152|interpro:IPR037152|interpro:IPR040919 ensemblfungi:YFL003C(gene)|ensemblfungi:YFL003C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005524"(ATP binding)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0062128"(MutSgamma complex)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|refseq:NP_116652.1|sgd:S000001891|mint:P40965|dip:DIP-2426N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lqv3qzZBu0sCtRdeXgJYCKIAsTU559292 rogid:iFhkRrFx9rw2iRzg7gJfv5eZwXk559292 intact-crc:3F0525779431C469|rigid:ph6Aig0BGY79YstLQAmBSTLD6Ac false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09959 uniprotkb:P10127 intact:EBI-18641|uniprotkb:D6VYI6|ensemblfungi:YLR182W intact:EBI-2233|uniprotkb:D6VV79|ensemblfungi:YGL256W psi-mi:swi6_yeast(display_long)|uniprotkb:SWI6(gene name)|psi-mi:SWI6(display_short)|uniprotkb:YLR182W(locus name)|uniprotkb:L9470.8(orf name)|uniprotkb:Cell-cycle box factor subunit SWI6(gene name synonym)|uniprotkb:Trans-acting activator of HO endonuclease gene(gene name synonym)|uniprotkb:MBF subunit P90(gene name synonym) psi-mi:adh4_yeast(display_long)|uniprotkb:ADH4(gene name)|psi-mi:ADH4(display_short)|uniprotkb:YGL256W(locus name)|uniprotkb:NRC465(orf name)|uniprotkb:ZRG5(gene name synonym)|uniprotkb:Alcohol dehydrogenase IV(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315296|imex:IM-14275-127 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR182W(gene)|ensemblfungi:YLR182W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010845"(positive regulation of reciprocal meiotic recombination)|go:"GO:0030907"(MBF transcription complex)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR040822|rcsb pdb:1SW6|rcsb pdb:2XFV|rcsb pdb:5XW5|refseq:NP_013283.1|sgd:S000004172|dip:DIP-598N|mint:P09959 refseq:NP_011258.2|sgd:S000003225|dip:DIP-4812N|mint:P10127|ensemblfungi:YGL256W(gene)|ensemblfungi:YGL256W_mRNA(transcript)|go:"GO:0000947"(amino acid catabolic process to alcohol via Ehrlich pathway)|go:"GO:0004022"("alcohol dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006113"(fermentation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001670(Iron-containing alcohol dehydrogenase)|interpro:IPR018211|interpro:IPR039697 psi-mi:"MI:0469"(intact) crc64:9B317FCACEEC493C crc64:7DFFD43830FB269B figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rtovwtMGdOLKrOttgos4Ej9V160559292 rogid:fbgaUT1lKT6O6lYODaI0xuqspzM559292 intact-crc:97BE49D9208FCD1C|rigid:VQR9kynYRuqHyZ1nrsqtzgOpmhM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15496 uniprotkb:P10174 intact:EBI-8902|ensemblfungi:YPL117C|uniprotkb:D6W3Q1 intact:EBI-2050505|uniprotkb:D6W082|ensemblfungi:YMR256C psi-mi:idi1_yeast(display_long)|uniprotkb:Isopentenyl pyrophosphate isomerase(gene name synonym)|uniprotkb:IDI1(gene name)|psi-mi:IDI1(display_short)|uniprotkb:BOT2(gene name synonym)|uniprotkb:YPL117C(locus name)|uniprotkb:LPH10C(orf name) psi-mi:cox7_yeast(display_long)|uniprotkb:Cytochrome c oxidase polypeptide VII(gene name synonym)|uniprotkb:YM9920.10C(orf name)|uniprotkb:YMR256C(locus name)|uniprotkb:COX7(gene name)|psi-mi:COX7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315307|imex:IM-14275-128 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL117C(gene)|ensemblfungi:YPL117C_mRNA(transcript)|go:"GO:0004452"(isopentenyl-diphosphate delta-isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009240"(isopentenyl diphosphate biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0045337"(farnesyl diphosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050992"(dimethylallyl diphosphate biosynthetic process)|reactome:R-SCE-191273|refseq:NP_015208.1|sgd:S000006038|interpro:IPR011876(Isopentenyl-diphosphate delta-isomerase, type 1)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|mint:P15496 refseq:NP_013983.1|sgd:S000004869|dip:DIP-7133N|mint:P10174|ensemblfungi:YMR256C(gene)|ensemblfungi:YMR256C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR014367(Cytochrome-c oxidase, subunit VII)|interpro:IPR039297|rcsb pdb:6GIQ|rcsb pdb:6HU9|rcsb pdb:6T0B|rcsb pdb:6T15|rcsb pdb:6YMX|rcsb pdb:6YMY psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:KQ9qSb2grQ4DQip7atYPeCwp5QM559292 rogid:M1MYkogBqnf3pNKOUwhEDLmVcds559292 intact-crc:9A838DFAF1C217B5|rigid:Z1Zz+8y/KaHdyixdBFjDRoiKzSE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38996 uniprotkb:P10174 intact:EBI-11776|uniprotkb:Q07034|ensemblfungi:YPL190C|uniprotkb:D6W3H8 intact:EBI-2050505|uniprotkb:D6W082|ensemblfungi:YMR256C psi-mi:nab3_yeast(display_long)|uniprotkb:YPL190C(locus name)|uniprotkb:NAB3(gene name)|psi-mi:NAB3(display_short)|uniprotkb:HMD1(gene name synonym) psi-mi:cox7_yeast(display_long)|uniprotkb:Cytochrome c oxidase polypeptide VII(gene name synonym)|uniprotkb:YM9920.10C(orf name)|uniprotkb:YMR256C(locus name)|uniprotkb:COX7(gene name)|psi-mi:COX7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315329|imex:IM-14275-130 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036621|rcsb pdb:2KVI|rcsb pdb:2L41|interpro:IPR035979|rcsb pdb:2XNQ|rcsb pdb:2XNR|ensemblfungi:YPL190C(gene)|ensemblfungi:YPL190C_mRNA(transcript)|go:"GO:0001068"(transcription regulatory region RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0030847"(termination of RNA polymerase II transcription, exosome-dependent)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0034472"(snRNA 3'-end processing)|go:"GO:0035649"(Nrd1 complex)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071041"(antisense RNA transcript catabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034167|refseq:NP_015134.1|sgd:S000006111|mint:P38996|dip:DIP-3980N refseq:NP_013983.1|sgd:S000004869|dip:DIP-7133N|mint:P10174|ensemblfungi:YMR256C(gene)|ensemblfungi:YMR256C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR014367(Cytochrome-c oxidase, subunit VII)|interpro:IPR039297|rcsb pdb:6GIQ|rcsb pdb:6HU9|rcsb pdb:6T0B|rcsb pdb:6T15|rcsb pdb:6YMX|rcsb pdb:6YMY psi-mi:"MI:0469"(intact) crc64:CD6D2C7F24A44993 - figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iVBA824UReQJmvua7xganVlrm9U559292 rogid:M1MYkogBqnf3pNKOUwhEDLmVcds559292 intact-crc:8D7AB111A54113E3|rigid:IgNskz2K2xvZuLvxntzFROvEF+I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25584 uniprotkb:P10174 intact:EBI-21765|uniprotkb:D6VQW1|ensemblfungi:YCL056C intact:EBI-2050505|uniprotkb:D6W082|ensemblfungi:YMR256C psi-mi:pex34_yeast(display_long)|uniprotkb:YCL056C(locus name)|uniprotkb:YCL56C(orf name)|uniprotkb:YCL433(orf name)|uniprotkb:PEX34(gene name)|psi-mi:PEX34(display_short)|uniprotkb:Peroxin-34(gene name synonym) psi-mi:cox7_yeast(display_long)|uniprotkb:Cytochrome c oxidase polypeptide VII(gene name synonym)|uniprotkb:YM9920.10C(orf name)|uniprotkb:YMR256C(locus name)|uniprotkb:COX7(gene name)|psi-mi:COX7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315318|imex:IM-14275-129 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000561|refseq:NP_009875.1|mint:P25584|dip:DIP-2040N|ensemblfungi:YCL056C(gene)|ensemblfungi:YCL056C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization) refseq:NP_013983.1|sgd:S000004869|dip:DIP-7133N|mint:P10174|ensemblfungi:YMR256C(gene)|ensemblfungi:YMR256C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR014367(Cytochrome-c oxidase, subunit VII)|interpro:IPR039297|rcsb pdb:6GIQ|rcsb pdb:6HU9|rcsb pdb:6T0B|rcsb pdb:6T15|rcsb pdb:6YMX|rcsb pdb:6YMY psi-mi:"MI:0469"(intact) crc64:6035D449766516A6 - figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IGoLOZeCbBNA4w+BG9mC/vxGfqs559292 rogid:M1MYkogBqnf3pNKOUwhEDLmVcds559292 intact-crc:49CFBCF777E267DC|rigid:7bqGR/7VGwJbc6jGlJdmCkFywSw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P10614 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315362|imex:IM-14275-133 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:5B22CA1CDA4EDB89|rigid:X5FwejromHj1R6ymC2sBhVVkB68 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P06197 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315351|imex:IM-14275-132 author score:95.85 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 psi-mi:"MI:0469"(intact) - crc64:6E2E62252B3CB5E2 figure legend:tables S3 and S4|author-confidence:95.85|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 intact-crc:99DBF7004C1DA2E4|rigid:dCiRI521kSt/jje/XwMI+BZNqk8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10174 uniprotkb:P52490 intact:EBI-2050505|uniprotkb:D6W082|ensemblfungi:YMR256C intact:EBI-19777|uniprotkb:D6VS79|ensemblfungi:YDR092W psi-mi:cox7_yeast(display_long)|uniprotkb:Cytochrome c oxidase polypeptide VII(gene name synonym)|uniprotkb:YM9920.10C(orf name)|uniprotkb:YMR256C(locus name)|uniprotkb:COX7(gene name)|psi-mi:COX7(display_short) psi-mi:ubc13_yeast(display_long)|uniprotkb:UBC13(gene name)|psi-mi:UBC13(display_short)|uniprotkb:YDR092W(locus name)|uniprotkb:YD6652.04(orf name)|uniprotkb:Ubiquitin-protein ligase 13(gene name synonym)|uniprotkb:Ubiquitin carrier protein 13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 13(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315340|imex:IM-14275-131 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013983.1|sgd:S000004869|dip:DIP-7133N|mint:P10174|ensemblfungi:YMR256C(gene)|ensemblfungi:YMR256C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR014367(Cytochrome-c oxidase, subunit VII)|interpro:IPR039297|rcsb pdb:6GIQ|rcsb pdb:6HU9|rcsb pdb:6T0B|rcsb pdb:6T15|rcsb pdb:6YMX|rcsb pdb:6YMY sgd:S000002499|ensemblfungi:YDR092W(gene)|ensemblfungi:YDR092W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006301"(postreplication repair)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0044395"(protein targeting to vacuolar membrane)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1JAT|rcsb pdb:1JBB|rcsb pdb:2GMI|rcsb pdb:4FH1|rcsb pdb:5OJW|reactome:R-SCE-8866654|reactome:R-SCE-9020702|reactome:R-SCE-9646399|reactome:R-SCE-983168|refseq:NP_010377.3|dip:DIP-5486N|mint:P52490 psi-mi:"MI:0469"(intact) - crc64:445558F8F193275B figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:M1MYkogBqnf3pNKOUwhEDLmVcds559292 rogid:5nTtjUZ2IpzHhrj1UU6NlaRW53k559292 intact-crc:C297FCF57C2E0C2E|rigid:FjkRUXRMTEhgTfVHgrvVpq9MJiw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P21147 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-2098|ensemblfungi:YGL055W|uniprotkb:D6VU86|uniprotkb:E9P911 psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:aco1_yeast(display_long)|uniprotkb:OLE1(gene name)|psi-mi:OLE1(display_short)|uniprotkb:Stearoyl-CoA desaturase 1(gene name synonym)|uniprotkb:Fatty acid desaturase 1(gene name synonym)|uniprotkb:YGL055W(locus name)|uniprotkb:Delta 9 fatty acid desaturase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315406|imex:IM-14275-137 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 ensemblfungi:YGL055W(gene)|ensemblfungi:YGL055W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0004768"(stearoyl-CoA 9-desaturase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|sgd:S000003023|refseq:NP_011460.3|dip:DIP-5026N|mint:P21147|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR001522(Fatty acid desaturase, type 1, C-terminal)|interpro:IPR005804(Fatty acid desaturase, type 1)|interpro:IPR009160(Delta-9 acyl-CoA desaturase with haem/steroid binding region)|interpro:IPR015876(Fatty acid desaturase, type 1, core)|interpro:IPR018506|interpro:IPR036400 psi-mi:"MI:0469"(intact) - crc64:A6CC78DD4210ECCA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:Ibp4I76IX/sMf5kLO05pTBZ3TNE559292 intact-crc:4EF184D262D2DED1|rigid:Xa+nl7qJFiwfdKVP+hWKzIPMR6w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P19807 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315395|imex:IM-14275-136 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:6199F5B188E029BB|rigid:BIf7lotJnUZfL/FZTDXt91O9xn8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17898 uniprotkb:P10614 intact:EBI-2050738|uniprotkb:D6W152|ensemblfungi:YNL130C intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:cpt1_yeast(display_long)|uniprotkb:Diacylglycerol cholinephosphotransferase 1(gene name synonym)|uniprotkb:Sn-1,2-diacylglycerol cholinephosphotransferase(gene name synonym)|uniprotkb:N1218(orf name)|uniprotkb:N1867(orf name)|uniprotkb:YNL130C(locus name)|uniprotkb:CPT1(gene name)|psi-mi:CPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase CPT1(gene name synonym) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315384|imex:IM-14275-135 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005074|refseq:NP_014269.4|dip:DIP-7848N|mint:P17898|ensemblfungi:YNL130C(gene)|ensemblfungi:YNL130C_mRNA(transcript)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006657"(CDP-choline pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213 refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:PsU8UELFPsbtbzOS6oBnXJAuk/A559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:65A5811C17E6F3ED|rigid:b72IlPKwv5/mFyjVY7IXG63ChFo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P16603 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-11940|ensemblfungi:YHR042W|uniprotkb:D3DKZ0 psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:ncpr_yeast(display_long)|uniprotkb:NCP1(gene name)|psi-mi:NCP1(display_short)|uniprotkb:NCPR1(gene name synonym)|uniprotkb:PRD1(gene name synonym)|uniprotkb:CPR1(gene name synonym)|uniprotkb:YHR042W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315373|imex:IM-14275-134 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 ensemblfungi:YHR042W(gene)|ensemblfungi:YHR042W_mRNA(transcript)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0003959"(NADPH dehydrogenase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0010181"(FMN binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0005739"(mitochondrion)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR023208|interpro:IPR039261|rcsb pdb:2BF4|rcsb pdb:2BN4|rcsb pdb:2BPO|rcsb pdb:3FJO|reactome:R-SCE-1222556|reactome:R-SCE-1474151|reactome:R-SCE-203615|reactome:R-SCE-392154|reactome:R-SCE-5218920|reactome:R-SCE-5578775|reactome:R-SCE-9009391|reactome:R-SCE-9033241|interpro:IPR029039|refseq:NP_011908.1|sgd:S000001084|mint:P16603|dip:DIP-8294N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:l8faixht4sd0KQhbt2DadH/8BPw559292 intact-crc:B5D1A524939C60A5|rigid:PwNLGPfglqjj5lSo8cJDggW8HRM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P28496 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-26585|uniprotkb:D6VXS8|ensemblfungi:YKL008C psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:lac1_yeast(display_long)|uniprotkb:LAC1(gene name)|psi-mi:LAC1(display_short)|uniprotkb:DGT1(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase LAC1(gene name synonym)|uniprotkb:YKL156(orf name)|uniprotkb:YKL008C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315439|imex:IM-14275-140 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 sgd:S000001491|refseq:NP_012917.3|mint:P28496|dip:DIP-4348N|ensemblfungi:YKL008C(gene)|ensemblfungi:YKL008C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0034399"(nuclear periphery)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:0061576"(acyl-CoA ceramide synthase complex)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR013599(TRAM1-like protein)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|reactome:R-SCE-1660661 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:gqRCCAHQcrRAHNO+R2LkQOzJ0mg559292 intact-crc:7FC5E0759E57A27F|rigid:7x8eT+dQkpucuart5ybvAkeex7g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:P10614 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315428|imex:IM-14275-139 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) crc64:8B7F009521F72C15 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:9047B647F2D83CB5|rigid:1H9iaK/k3HMDL9zYMliDNbQkC1A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21825 uniprotkb:P10614 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315417|imex:IM-14275-138 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:B399A6D5AFF151EB|rigid:slm7VN0/j8rnYotR0hCbhBCN+qc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:P10614 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315472|imex:IM-14275-143 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:30068D64D66B59A9|rigid:W3389/Q6OBSmKYAMMGQNM6LX5hs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P32353 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-6554|uniprotkb:D6VY58|ensemblfungi:YLR056W psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:erg3_yeast(display_long)|uniprotkb:SYR1(gene name synonym)|uniprotkb:L2150(orf name)|uniprotkb:YLR056W(locus name)|uniprotkb:ERG3(gene name)|psi-mi:ERG3(display_short)|uniprotkb:PSO6(gene name synonym)|uniprotkb:Sterol-C5-desaturase(gene name synonym)|uniprotkb:"Ergosterol Delta(5,6) desaturase"(gene name synonym)|uniprotkb:C-5 sterol desaturase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315461|imex:IM-14275-142 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_013157.1|sgd:S000004046|mint:P32353|dip:DIP-4136N|ensemblfungi:YLR056W(gene)|ensemblfungi:YLR056W_mRNA(transcript)|go:"GO:0000248"(C-5 sterol desaturase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0050046"("delta7-sterol 5(6)-desaturase activity")|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-SCE-6807047|reactome:R-SCE-6807062 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:zO926fj34KkGCJAI6vTmiICpUSc559292 intact-crc:4EC19EB259EE797C|rigid:KBX5l90H0ULyBNphm7Czqwao/AE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32340 uniprotkb:P10614 intact:EBI-11961|ensemblfungi:YML120C|uniprotkb:D6W0G4 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:ndi1_yeast(display_long)|uniprotkb:NDI1(gene name)|psi-mi:NDI1(display_short)|uniprotkb:YML120C(locus name)|uniprotkb:YM7056.06C(orf name)|uniprotkb:"NADH:ubiquinone reductase (non-electrogenic)"(gene name synonym)|uniprotkb:Internal NADH dehydrogenase(gene name synonym) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315450|imex:IM-14275-141 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4G6H|ensemblfungi:YML120C(gene)|ensemblfungi:YML120C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006116"(NADH oxidation)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR023753|interpro:IPR036188|rcsb pdb:4G6G|rcsb pdb:4G74|rcsb pdb:4G9K|rcsb pdb:4GAP|rcsb pdb:4GAV|rcsb pdb:5YJW|rcsb pdb:5YJX|rcsb pdb:4G73|refseq:NP_013586.1|sgd:S000004589|mint:P32340|dip:DIP-5554N refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) crc64:E3A43D75A1ADCF3B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5vlSvD0red3g+OL8YtfHKmts3gI559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:2F5246E319F76FDF|rigid:ohkpxGH4XLv8793ZHduqVj0OgtU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P36027 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315505|imex:IM-14275-146 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:29B2449ECC103B3F|rigid:7/PXPh4OFNnpK7xpeCnb838sqWQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36024 uniprotkb:P10614 intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315494|imex:IM-14275-145 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024 refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:397E25C4AB9CD9C2|rigid:Q/x3bSz/+tEkhw3YyDK2vZNyaBk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P35844 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-9648|ensemblfungi:YPL145C|uniprotkb:D6W3M4|uniprotkb:E9P8U8 psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:kes1_yeast(display_long)|uniprotkb:KES1(gene name)|psi-mi:KES1(display_short)|uniprotkb:OSH4(gene name synonym)|uniprotkb:Protein KES1(gene name synonym)|uniprotkb:LPI3C(orf name)|uniprotkb:P2614(orf name)|uniprotkb:YPL145C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315483|imex:IM-14275-144 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 ensemblfungi:YPL145C(gene)|ensemblfungi:YPL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035621"(ER to Golgi ceramide transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|rcsb pdb:1ZHT|rcsb pdb:1ZHW|rcsb pdb:1ZHX|rcsb pdb:1ZHY|rcsb pdb:1ZHZ|rcsb pdb:1ZI7|rcsb pdb:3SPW|rcsb pdb:4F4B|rcsb pdb:4FES|rcsb pdb:4JCH|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_015180.1|sgd:S000006066|dip:DIP-2867N|mint:P35844 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:6vsHrA4RScGr2+xmii0wiuvK1OM559292 intact-crc:24F3C1E6E54CA5CB|rigid:JIffjXWNfmhGvsLUBMfq8fxa6oM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P38751 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-24305|uniprotkb:Q07190|uniprotkb:D3DKQ9|ensemblfungi:YHL006C psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:shu1_yeast(display_long)|uniprotkb:SHU1(gene name)|psi-mi:SHU1(display_short)|uniprotkb:YHL006C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315549|imex:IM-14275-150 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 sgd:S000000998|refseq:NP_011857.2|dip:DIP-1874N|mint:P38751|ensemblfungi:YHL006C(gene)|ensemblfungi:YHL006C_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0097196"(Shu complex)|rcsb pdb:5XYN psi-mi:"MI:0469"(intact) - crc64:8B17700BDAA2367F figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:lldO459lg8WMtT2I4D2uMc2bLM4559292 intact-crc:EE7821088CF12F60|rigid:bgrzC3Pjgvda7XSXsEPr+fPiiS4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P38353 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-18175|uniprotkb:D6VQS8|ensemblfungi:YBR283C psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:ssh1_yeast(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:Ssh1 complex subunit alpha(gene name synonym)|uniprotkb:Ssh1 complex subunit SSH1(gene name synonym)|uniprotkb:YBR2020(orf name)|uniprotkb:YBR283C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315538|imex:IM-14275-149 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_009842.1|sgd:S000000487|ensemblfungi:YBR283C(gene)|ensemblfungi:YBR283C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:2WW9|rcsb pdb:2WWA|dip:DIP-4962N|mint:P38353 psi-mi:"MI:0469"(intact) - crc64:48267EEA3E0191BD figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:76wvZIdv7W5BQn6wI+sHOGQAyuc559292 intact-crc:2C42C810EB810418|rigid:gOvkhXwlFbYV0Z4M+4VteLrIdv8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:P10614 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315527|imex:IM-14275-148 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:7EDC6F967304A6A0|rigid:jJzGgVOVB2Gwn0cU8ARDwuEJJhg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P36076 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315516|imex:IM-14275-147 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:Li7vZOassm4PC5fW111/j5ivgEc559292 intact-crc:B22D6EAF5EC6404C|rigid:eZ7trzF9IOI0Pw8Yl8Oli0oXBn0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P40581 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-7869|ensemblfungi:YIR037W|uniprotkb:D6VVW8 psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:gpx3_yeast(display_long)|uniprotkb:HYR1(gene name)|psi-mi:HYR1(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:Hydrogen peroxide resistance protein 1(gene name synonym)|uniprotkb:Oxidant receptor peroxidase 1(gene name synonym)|uniprotkb:Phospholipid hydroperoxide glutathione peroxidase 3(gene name synonym)|uniprotkb:GPX3(gene name synonym)|uniprotkb:YIR037W(locus name)|uniprotkb:Glutathione peroxidase homolog 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315593|imex:IM-14275-154 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_012303.1|sgd:S000001476|ensemblfungi:YIR037W(gene)|ensemblfungi:YIR037W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR029760|interpro:IPR036249|rcsb pdb:3CMI|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661|interpro:IPR029759|mint:P40581|dip:DIP-1275N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:Pi8aaZEVc33CTMPyaM0mpscvLU4559292 intact-crc:867F3E2F4356E380|rigid:HrchyQpBgfudR/IRLgRGN3+dgak false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P40540 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315582|imex:IM-14275-153 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) - crc64:6DBEEEE7722203B0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 intact-crc:8645197CCF1ACE5F|rigid:qE7Jk91vPqy42x85B5hkH1UDtLI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P38992 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-18574|ensemblfungi:YDR297W|uniprotkb:D6VSS6 psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:sur2_yeast(display_long)|uniprotkb:SUR2(gene name)|psi-mi:SUR2(display_short)|uniprotkb:SYR2(gene name synonym)|uniprotkb:YDR297W(locus name)|uniprotkb:D9740.8(orf name)|uniprotkb:Syringomycin response protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315571|imex:IM-14275-152 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0042284"(sphingolipid delta-4 desaturase activity)|interpro:IPR006694(Fatty acid hydroxylase)|go:"GO:0006665"(sphingolipid metabolic process)|ensemblfungi:YDR297W(gene)|ensemblfungi:YDR297W_mRNA(transcript)|go:"GO:0000170"(sphingosine hydroxylase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|refseq:NP_010583.1|sgd:S000002705|dip:DIP-7741N|mint:P38992 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:HcXW6Nko6+g+16d/ehjh8p2sl8Y559292 intact-crc:4850AF2928B04D8D|rigid:tR/5lsJVAFhzxax6EJL3rw/2q/g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38985 uniprotkb:P10614 intact:EBI-17977|uniprotkb:D6VRQ6|ensemblfungi:YDL092W intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:srp14_yeast(display_long)|uniprotkb:SRP14(gene name)|psi-mi:SRP14(display_short)|uniprotkb:YDL092W(locus name)|uniprotkb:D2404(orf name)|uniprotkb:Signal recognition particle 14 kDa protein homolog(gene name synonym) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315560|imex:IM-14275-151 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010191.1|sgd:S000002250|ensemblfungi:YDL092W(gene)|ensemblfungi:YDL092W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR003210(Signal recognition particle, SRP14 subunit)|interpro:IPR009018(Signal recognition particle, SRP9/SRP14 subunit)|reactome:R-SCE-1799339|reactome:R-SCE-6798695|dip:DIP-4864N|mint:P38985 refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I9myDFdKPRnrKsHBhWBxI/Em7EQ559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:872DA4B0F758227D|rigid:FCpAJWnlWDKYbhetYK2a07sHwp0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P47155 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-2051644|uniprotkb:D6VWT7|ensemblfungi:YJR118C psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:ilm1_yeast(display_long)|uniprotkb:Increased loss of mitochondrial DNA protein 1(gene name synonym)|uniprotkb:J2033(orf name)|uniprotkb:ILM1(gene name)|psi-mi:ILM1(display_short)|uniprotkb:YJR118C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315626|imex:IM-14275-157 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 sgd:S000003879|interpro:IPR018815|refseq:NP_012652.3|mint:P47155|ensemblfungi:YJR118C(gene)|ensemblfungi:YJR118C_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:BrQhbXGvUjNG6Bt5c0J7T8qzMeI559292 intact-crc:353E4FB358B3782E|rigid:X7JUREYH76vqG91P7weK48zSFWs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P47154 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-18298|uniprotkb:D6VWT6|ensemblfungi:YJR117W psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:ste24_yeast(display_long)|uniprotkb:STE24(gene name)|psi-mi:STE24(display_short)|uniprotkb:AFC1(gene name synonym)|uniprotkb:YJR117W(locus name)|uniprotkb:J2032(orf name)|uniprotkb:Prenyl protein-specific endoprotease 1(gene name synonym)|uniprotkb:A-factor-converting enzyme(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315615|imex:IM-14275-156 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_012651.1|sgd:S000003878|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016485"(protein processing)|go:"GO:0019236"(response to pheromone)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0071432"(peptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion)|go:"GO:0071586"(CAAX-box protein processing)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR001915(Peptidase M48, Ste24p)|interpro:IPR027057|interpro:IPR032456|go:"GO:0005637"(nuclear inner membrane)|ensemblfungi:YJR117W(gene)|ensemblfungi:YJR117W_mRNA(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|dip:DIP-1390N|mint:P47154 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:HElgJQdYMPeUIEgcRxlHUnBCkgQ559292 intact-crc:AA8744957CF7267A|rigid:wB5FuHCDCqKm+K7yq6qe1wJLXOo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P40582 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-7941|uniprotkb:D6VVW9|ensemblfungi:YIR038C psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:gst1_yeast(display_long)|uniprotkb:YIR038C(locus name)|uniprotkb:GTT1(gene name)|psi-mi:GTT1(display_short)|uniprotkb:GST-I(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315604|imex:IM-14275-155 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_012304.1|sgd:S000001477|mint:P40582|dip:DIP-2103N|ensemblfungi:YIR038C(gene)|ensemblfungi:YIR038C_mRNA(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010731"(protein glutathionylation)|go:"GO:0071944"(cell periphery)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079 psi-mi:"MI:0469"(intact) - crc64:3C07D40D29F60DFF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:+bqzHpsoLw4j2qQBzHbkfldR5OU559292 intact-crc:96B423452D4A017D|rigid:EUDo9cFxDSS2ktdTYPruqnJ/KnY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54781 uniprotkb:P10614 intact:EBI-6563|uniprotkb:D6VZI9|uniprotkb:E9P965|ensemblfungi:YMR015C intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:erg5_yeast(display_long)|uniprotkb:ERG5(gene name)|psi-mi:ERG5(display_short)|uniprotkb:CYP61(gene name synonym)|uniprotkb:YMR015C(locus name)|uniprotkb:YM9711.02C(orf name)|uniprotkb:C-22 sterol desaturase(gene name synonym) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315659|imex:IM-14275-160 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013728.1|sgd:S000004617|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR036396|mint:P54781|ensemblfungi:YMR015C(gene)|ensemblfungi:YMR015C_mRNA(transcript)|go:"GO:0000249"(C-22 sterol desaturase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ScwspGheTequLP3AGjoNZM3cp3E559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:E7C2F812EE8F3BD9|rigid:LoXzRVbpui5CxiF8eT/XJAq1sfQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P53337 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315648|imex:IM-14275-159 author score:89.17 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:89.17|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 intact-crc:4C399B286A5F951B|rigid:WgXf9N7koMQfCAEVbWx+LY+rRIU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P53049 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315637|imex:IM-14275-158 author score:97.40 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 intact-crc:E70E20477E76B1C1|rigid:68EHhOxjZolon782Pc5mpH5FXcU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P54837 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315670|imex:IM-14275-161 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:E97821050134965C|rigid:CvwyLcysts7uCBa7qdmhy/9LtNY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:Q02201 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-12636|uniprotkb:D6VXT9|ensemblfungi:YKR003W psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:osh6_yeast(display_long)|uniprotkb:YK102(orf name)|uniprotkb:YKR003W(locus name)|uniprotkb:OSH6(gene name)|psi-mi:OSH6(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315681|imex:IM-14275-162 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0015914"(phospholipid transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0120015"(sterol transfer activity)|rcsb pdb:4B2Z|rcsb pdb:4PH7|reactome:R-SCE-1482801|reactome:R-SCE-192105|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensemblfungi:YKR003W(gene)|ensemblfungi:YKR003W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|refseq:NP_012928.1|sgd:S000001711|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|mint:Q02201 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:aOZdSdLn96ns0C9w9E3r62iNyYo559292 intact-crc:DB65D81C1E266167|rigid:tCG74YjNB9weJcmrz7F8Z50oWh8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02774 uniprotkb:P10614 intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315692|imex:IM-14275-163 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:3EB2F1CE794439DE|rigid:CFLmcv+Va2LHm9vj12eZEZA1N28 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:Q04080 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-7777|uniprotkb:D6VT61|ensemblfungi:YDR434W psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:gpi17_yeast(display_long)|uniprotkb:GPI17(gene name)|psi-mi:GPI17(display_short)|uniprotkb:D9461.20(orf name)|uniprotkb:YDR434W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315703|imex:IM-14275-164 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 sgd:S000002842|interpro:IPR019540|refseq:NP_010722.3|mint:Q04080|ensemblfungi:YDR434W(gene)|ensemblfungi:YDR434W_mRNA(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:7bBqUoVPfAOj/Pm4RPbzshzWNr0559292 intact-crc:710043D08B3B02F5|rigid:Ba99T8q5ebcyF5I3+3Kg0RQR2+s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:Q06144 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315736|imex:IM-14275-167 author score:97.40 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:2F474503CAB7C195 figure legend:tables S3 and S4|author-confidence:97.40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 intact-crc:B048B8FBC5F26192|rigid:J/PGi6hINYchf3vmFOirOIs3s/A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:Q05359 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315725|imex:IM-14275-166 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 intact-crc:F3E1352DAB2161EA|rigid:AHvAsNmcEvv+EvhdTTZ9f/zvppM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04969 uniprotkb:P10614 intact:EBI-27827|uniprotkb:D6VZB9|ensemblfungi:YML055W intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:spc2_yeast(display_long)|uniprotkb:YML055W(locus name)|uniprotkb:YM9958.07(orf name)|uniprotkb:SPC2(gene name)|psi-mi:SPC2(display_short)|uniprotkb:SPY1(gene name synonym)|uniprotkb:Microsomal signal peptidase subunit 2(gene name synonym) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315714|imex:IM-14275-165 author score:86.47 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013657.1|sgd:S000004519|dip:DIP-4540N|mint:Q04969|ensemblfungi:YML055W(gene)|ensemblfungi:YML055W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:86.47|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZXf9rPA3/ryPnDqI4JGp0VMNMe4559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:9B92FB153EA88F67|rigid:MJeRSwJlXwbDDD8BVO9ru+YWPrE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99287 uniprotkb:P10614 intact:EBI-37523|uniprotkb:D6W2M3|ensemblfungi:YOR165W intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:sey1_yeast(display_long)|uniprotkb:SEY1(gene name)|psi-mi:SEY1(display_short)|uniprotkb:YOR165W(locus name)|uniprotkb:Synthetic enhancer of YOP1 protein(gene name synonym)|uniprotkb:O3590(orf name) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315791|imex:IM-14275-172 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014808.1|sgd:S000005691|dip:DIP-49373N|mint:Q99287|ensemblfungi:YOR165W(gene)|ensemblfungi:YOR165W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0061024"(membrane organization)|go:"GO:0071944"(cell periphery)|interpro:IPR008803(Root hair defective 3 GTP-binding)|interpro:IPR027417|interpro:IPR030386 refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) crc64:DEC0C9EC3AB172DF - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zFsgalfyUvAuuV51vChJjraiQmI559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:E3A7165752050F39|rigid:wQxRKzBsAcZtXlVf5hzUi4OaA3Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12443 uniprotkb:P10614 intact:EBI-32591|uniprotkb:D6VRF0|ensemblfungi:YDL204W intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:rtn2_yeast(display_long)|uniprotkb:RTN2(gene name)|psi-mi:RTN2(display_short)|uniprotkb:D1062(orf name)|uniprotkb:YDL204W(locus name) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315780|imex:IM-14275-171 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010077.1|sgd:S000002363|dip:DIP-4231N|mint:Q12443|ensemblfungi:YDL204W(gene)|ensemblfungi:YDL204W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071788"(endoplasmic reticulum tubular network maintenance)|go:"GO:0071944"(cell periphery)|interpro:IPR003388(Reticulon) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) crc64:E937E2B77759DFF5 - figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jF49AeaM5t7a5TBw3/+tJ7H251g559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:A366288BA014DBA8|rigid:TtY7kWjqxRhgn8f8JHHcwJj0O3Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12256 uniprotkb:P10614 intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315769|imex:IM-14275-170 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:50840B9806E0D4C8|rigid:TbnE/ji9JQt/g5SioL7CIzhHMYQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12168 uniprotkb:P10614 intact:EBI-32973|uniprotkb:Q07268|uniprotkb:D6VYD8|ensemblfungi:YLR144C intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:eng2_yeast(display_long)|uniprotkb:ACF2(gene name)|psi-mi:ACF2(display_short)|uniprotkb:YLR144C(locus name)|uniprotkb:Laminarinase-2(gene name synonym)|uniprotkb:ENG2(gene name synonym)|uniprotkb:PCA1(gene name synonym)|uniprotkb:L3180(orf name) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315758|imex:IM-14275-169 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013245.1|sgd:S000004134|mint:Q12168|dip:DIP-2889N|ensemblfungi:YLR144C(gene)|ensemblfungi:YLR144C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042973"(glucan endo-1,3-beta-D-glucosidase activity)|go:"GO:0052861"(glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group)|go:"GO:0052862"(glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group)|interpro:IPR005200(Glycoside hydrolase, family 81)|interpro:IPR040451|interpro:IPR040720 refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8STCUe6Ie2CnTTBMjY8wrld5h44559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:8EC943AB827F916B|rigid:82qkV/lQoBFHSuguMfrW7OWAZNI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:Q08967 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-36673|uniprotkb:D6W3E9|ensemblfungi:YPL221W psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:flc1_yeast(display_long)|uniprotkb:FAD transporter 1(gene name synonym)|uniprotkb:FLC1(gene name)|psi-mi:FLC1(display_short)|uniprotkb:TRP-like ion channel protein FLC1(gene name synonym)|uniprotkb:Heme utilization factor 1(gene name synonym)|uniprotkb:Bypass of PAM1 protein 1(gene name synonym)|uniprotkb:HUF1(gene name synonym)|uniprotkb:YPL221W(locus name)|uniprotkb:BOP1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315747|imex:IM-14275-168 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_015103.1|sgd:S000006142|mint:Q08967|dip:DIP-3965N|ensemblfungi:YPL221W(gene)|ensemblfungi:YPL221W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055085"(transmembrane transport)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:r6CcZGEjxHUk2w0iBUBvnAPaFd4559292 intact-crc:14CF41B3E8D7A182|rigid:wNEJjiUBA+pDFt4HMakImFj7mhU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25623 uniprotkb:P10823 intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315824|imex:IM-14275-175 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) crc64:6F35C8F1562E41CC crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:6224AB3ECB94D8A2|rigid:Q2nLwmJHEfXV3GdHcTdIbsohTZM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10823 uniprotkb:P25619 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315813|imex:IM-14275-174 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) crc64:881B91792AE91748 crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:937E2F5EC5B08A4E|rigid:oIWF1wybgdj/NDRZNc1SKGCJaX8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:P10823 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315802|imex:IM-14275-173 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) - crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:1625C79EBF550E04|rigid:+2t39dgCRTjAeE84tJ29AiWEfsA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P10823 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315846|imex:IM-14275-177 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) - crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:7C53C8096517C7D4|rigid:H1JumMLYApoN6M2GRn475gHAlRs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10823 uniprotkb:P33413 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W intact:EBI-2060312|uniprotkb:D3DKP5|ensemblfungi:YHL016C psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:dur3_yeast(display_long)|uniprotkb:DUR3(gene name)|psi-mi:DUR3(display_short)|uniprotkb:YHL016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315835|imex:IM-14275-176 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 interpro:IPR031155|refseq:NP_011847.1|sgd:S000001008|interpro:IPR001734(Na+/solute symporter)|interpro:IPR038377|mint:P33413|ensemblfungi:YHL016C(gene)|ensemblfungi:YHL016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0015204"(urea transmembrane transporter activity)|go:"GO:0015489"(putrescine transmembrane transporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015840"(urea transport)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) crc64:881B91792AE91748 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rogid:oTFsdtOngA3q5wCbhK/fpVlIsz0559292 intact-crc:1F0A87C17E355052|rigid:QcUlJsj0h7cgy6pzFnPIV186KVQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10823 uniprotkb:P40260 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W intact:EBI-10714|ensemblfungi:YGR121C|uniprotkb:D6VUQ2 psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:mep1_yeast(display_long)|uniprotkb:MEP1(gene name)|psi-mi:MEP1(display_short)|uniprotkb:YGR121C(locus name)|uniprotkb:G6331(orf name)|uniprotkb:AMT1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315890|imex:IM-14275-181 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 ensemblfungi:YGR121C(gene)|ensemblfungi:YGR121C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|sgd:S000003353|refseq:NP_011636.3|mint:P40260|dip:DIP-5530N psi-mi:"MI:0469"(intact) crc64:881B91792AE91748 - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rogid:VnoBl5jhQD24N0SbCLv68HCwl1U559292 intact-crc:DFF7B98A8D36F891|rigid:A8CjuupOOI7jYlzX2pJWZfvxNsc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10823 uniprotkb:P39719 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W intact:EBI-20703|uniprotkb:Q05165|uniprotkb:D6VPG5|ensemblfungi:YAL053W psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:flc2_yeast(display_long)|uniprotkb:YAL053W(locus name)|uniprotkb:FLC2(gene name)|psi-mi:FLC2(display_short)|uniprotkb:FAD transporter 2(gene name synonym)|uniprotkb:TRP-like ion channel FLC2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315879|imex:IM-14275-180 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 refseq:NP_009348.2|sgd:S000000049|ensemblfungi:YAL053W(gene)|ensemblfungi:YAL053W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241|go:"GO:0055085"(transmembrane transport)|dip:DIP-6708N|mint:P39719 psi-mi:"MI:0469"(intact) crc64:881B91792AE91748 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rogid:NOmMW54DNa0o7vM945DlZgVUy44559292 intact-crc:9EC70035BD5A0D24|rigid:ceNsD1VGjFiGInloaZEDPF885OQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10823 uniprotkb:P38234 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315868|imex:IM-14275-179 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 psi-mi:"MI:0469"(intact) crc64:881B91792AE91748 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 intact-crc:0D467CAEF223A438|rigid:FMUw3K7gpigjOf/i3LYS0XgfnNg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:P10823 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315857|imex:IM-14275-178 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) - crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:5E090A81F2351C80|rigid:SZGirmyUt0IM/aaA0NGTA9nOgT0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47072 uniprotkb:P10823 intact:EBI-25803|uniprotkb:D6VWG2|uniprotkb:P47071|uniprotkb:Q86ZR5|ensemblfungi:YJL016W intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:yjb6_yeast(display_long)|uniprotkb:J1320(orf name)|uniprotkb:J1326(orf name)|uniprotkb:YJL017W(orf name)|uniprotkb:YJL016W(locus name) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315901|imex:IM-14275-182 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003553|refseq:NP_012518.2|mint:P47072|dip:DIP-4907N|ensemblfungi:YJL016W(gene)|ensemblfungi:YJL016W_mRNA(transcript)|go:"GO:0005737"(cytoplasm) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) crc64:21D1541BCFEFDFF6 crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XRf3g3pILUK7J16Tol90s1MoEY4559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:61441DF1D9860977|rigid:vc0d6PvlZieNPWArk2VoI5rYGtw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53049 uniprotkb:P10823 intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315923|imex:IM-14275-184 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) - crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:90B5689849C3967E|rigid:fXVt6fiITSm2IZV4m6GwhILGD04 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10823 uniprotkb:P50276 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315912|imex:IM-14275-183 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) crc64:881B91792AE91748 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:BED187D42893C213|rigid:/j3yZZ5fatWA4/EbJDgh+GjaXWc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53390 uniprotkb:P10823 intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315967|imex:IM-14275-188 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) crc64:2309338F36D96258 crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:8DEB4F3AD162D344|rigid:L4jBysHxaG2e3xJOVn1+jC5g/gM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10823 uniprotkb:P53283 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315956|imex:IM-14275-187 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:881B91792AE91748 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 intact-crc:932EB4E2927DE013|rigid:FdAoO2U5Yn7Jj1knbt2cL2lNVMM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53278 uniprotkb:P10823 intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315945|imex:IM-14275-186 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) crc64:D482327C9274C026 crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:624E17D110159F20|rigid:+0OpsHZEAfFlt/eU1Y77iHeNlVY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53139 uniprotkb:P10823 intact:EBI-23908|uniprotkb:D6VU38|ensemblfungi:YGL108C intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:ygk8_yeast(display_long)|uniprotkb:G3070(orf name)|uniprotkb:YGL108C(locus name) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315934|imex:IM-14275-185 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003076|refseq:NP_011407.3|mint:P53139|ensemblfungi:YGL108C(gene)|ensemblfungi:YGL108C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) - crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6rg2zcMN57peeKKy/RolIDcNaLc559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:097E0DB0B1AC7E11|rigid:sFqBW1IjyJuF9dcFlBD0dH+QSoU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02201 uniprotkb:P10823 intact:EBI-12636|uniprotkb:D6VXT9|ensemblfungi:YKR003W intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:osh6_yeast(display_long)|uniprotkb:YK102(orf name)|uniprotkb:YKR003W(locus name)|uniprotkb:OSH6(gene name)|psi-mi:OSH6(display_short) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315989|imex:IM-14275-190 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0015914"(phospholipid transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0120015"(sterol transfer activity)|rcsb pdb:4B2Z|rcsb pdb:4PH7|reactome:R-SCE-1482801|reactome:R-SCE-192105|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensemblfungi:YKR003W(gene)|ensemblfungi:YKR003W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|refseq:NP_012928.1|sgd:S000001711|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|mint:Q02201 sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) - crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aOZdSdLn96ns0C9w9E3r62iNyYo559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:ACDE93A3299346D8|rigid:IQ+lVhrYq8wgszl3XAeCHou/Btc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53832 uniprotkb:P10823 intact:EBI-2055941|uniprotkb:D6W0R1|ensemblfungi:YNL283C intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:wsc2_yeast(display_long)|uniprotkb:YNL283C(locus name)|uniprotkb:N0583(orf name)|uniprotkb:WSC2(gene name)|psi-mi:WSC2(display_short) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6315978|imex:IM-14275-189 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014116.1|sgd:S000005227|interpro:IPR002889(Carbohydrate-binding WSC)|mint:P53832|ensemblfungi:YNL283C(gene)|ensemblfungi:YNL283C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) - crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5wadvTv6SxcIAb60yfnuGMfa8pY559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:11A2FE3AA3B5641D|rigid:V5sqhyKczRI87po749EzLXN7kmY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10823 uniprotkb:Q03640 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316011|imex:IM-14275-192 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) crc64:881B91792AE91748 crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:94E356B209437801|rigid:mzM5b8zyXETn2VX9kzDVt1oellc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10823 uniprotkb:Q02785 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316000|imex:IM-14275-191 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) crc64:881B91792AE91748 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:DAD3539FA0F32F5C|rigid:4Ob470pz0RJQpi7AOHA77UaTQP0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06689 uniprotkb:P10823 intact:EBI-38659|uniprotkb:D6VZ50|ensemblfungi:YLR413W intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:yl413_yeast(display_long)|uniprotkb:YLR413W(locus name) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316044|imex:IM-14275-195 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013517.1|sgd:S000004405|mint:Q06689|dip:DIP-5075N|ensemblfungi:YLR413W(gene)|ensemblfungi:YLR413W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0071944"(cell periphery)|interpro:IPR009571(SUR7) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) crc64:92E23436DC857E95 crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AoTGKjLhw0NECrtuftZqLANonds559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:48533CF1F78A19CB|rigid:YQuHq+UE//6T7uWSPjRN4yIao58 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10823 uniprotkb:Q06451 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W intact:EBI-34275|uniprotkb:D6W4F2|ensemblfungi:YPR156C psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:tpo3_yeast(display_long)|uniprotkb:TPO3(gene name)|psi-mi:TPO3(display_short)|uniprotkb:P9584.7(orf name)|uniprotkb:YPR156C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316033|imex:IM-14275-194 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 refseq:NP_015482.1|sgd:S000006360|mint:Q06451|dip:DIP-3907N|ensemblfungi:YPR156C(gene)|ensemblfungi:YPR156C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:881B91792AE91748 crc64:D260ED161F800502 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rogid:oVpx7Bjk/mK2Q7+/j05tX3gHw7k559292 intact-crc:B5E54FCC41F92751|rigid:CCROSOylvKboa2omT8dGSrH/en8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10823 uniprotkb:Q06170 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W intact:EBI-35994|uniprotkb:D6VYW8|ensemblfungi:YLR326W psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:yl326_yeast(display_long)|uniprotkb:YLR326W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316022|imex:IM-14275-193 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 refseq:NP_013430.1|sgd:S000004318|mint:Q06170|dip:DIP-3995N|ensemblfungi:YLR326W(gene)|ensemblfungi:YLR326W_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR025187 psi-mi:"MI:0469"(intact) crc64:881B91792AE91748 crc64:724CD7833AA9B416 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rogid:Ufkoj1kRp4Y9JTsgbL+3k8hzJyo559292 intact-crc:FAF717A10FF8239C|rigid:L4IXl4UI3UqdxUegOgxXR6INgP4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10823 uniprotkb:Q12256 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316077|imex:IM-14275-198 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:881B91792AE91748 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 intact-crc:273F45873975F377|rigid:62uof8VOC8J/ayzKDcJKNwch+TA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08967 uniprotkb:P10823 intact:EBI-36673|uniprotkb:D6W3E9|ensemblfungi:YPL221W intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:flc1_yeast(display_long)|uniprotkb:FAD transporter 1(gene name synonym)|uniprotkb:FLC1(gene name)|psi-mi:FLC1(display_short)|uniprotkb:TRP-like ion channel protein FLC1(gene name synonym)|uniprotkb:Heme utilization factor 1(gene name synonym)|uniprotkb:Bypass of PAM1 protein 1(gene name synonym)|uniprotkb:HUF1(gene name synonym)|uniprotkb:YPL221W(locus name)|uniprotkb:BOP1(gene name synonym) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316066|imex:IM-14275-197 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015103.1|sgd:S000006142|mint:Q08967|dip:DIP-3965N|ensemblfungi:YPL221W(gene)|ensemblfungi:YPL221W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055085"(transmembrane transport)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241 sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) - crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:r6CcZGEjxHUk2w0iBUBvnAPaFd4559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:63740FACD742863D|rigid:VsgRXX7A+5bWj8pq9+cQhplWCeA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P10823 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316055|imex:IM-14275-196 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) - crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:D4FCB441EF0E4A9C|rigid:MjHP4MgZQkd/rG/f8ZdcrlgCPhw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10823 uniprotkb:Q3E756 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W intact:EBI-2044812|uniprotkb:D6VPX0|ensemblfungi:YBL029C-A psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:yb029_yeast(display_long)|uniprotkb:YBL029C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316099|imex:IM-14275-200 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 sgd:S000007591|refseq:NP_076874.1|mint:Q3E756|ensemblfungi:YBL029C-A(gene)|ensemblfungi:YBL029C-A_mRNA(transcript)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) crc64:881B91792AE91748 - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rogid:Y9LDkESr65DK5SLFNTw1dBKeqPc559292 intact-crc:BCE9EC235CF34EC5|rigid:smwCvET1mAVHsw+gsImcS/1+qQ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12335 uniprotkb:P10823 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316088|imex:IM-14275-199 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) crc64:1056E7A1F3E82288 crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:DF64916E88930DBB|rigid:sZS9M6fqPwAYoZGbnuS40qhtDkY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10963 uniprotkb:P10963 intact:EBI-13770|uniprotkb:E9P963|ensemblfungi:YKR097W|uniprotkb:D6VXF8 intact:EBI-13770|uniprotkb:E9P963|ensemblfungi:YKR097W|uniprotkb:D6VXF8 psi-mi:pcka_yeast(display_long)|uniprotkb:PCK1(gene name)|psi-mi:PCK1(display_short)|uniprotkb:PEPC(gene name synonym)|uniprotkb:PPC1(gene name synonym)|uniprotkb:YKR097W(locus name) psi-mi:pcka_yeast(display_long)|uniprotkb:PCK1(gene name)|psi-mi:PCK1(display_short)|uniprotkb:PEPC(gene name synonym)|uniprotkb:PPC1(gene name synonym)|uniprotkb:YKR097W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316110|imex:IM-14275-201 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YKR097W(gene)|ensemblfungi:YKR097W_mRNA(transcript)|go:"GO:0004612"("phosphoenolpyruvate carboxykinase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|sgd:S000001805|interpro:IPR001272(Phosphoenolpyruvate carboxykinase, ATP-utilising)|interpro:IPR013035(Phosphoenolpyruvate carboxykinase, C-terminal)|interpro:IPR008210(Phosphoenolpyruvate carboxykinase, N-terminal)|interpro:IPR015994("Phosphoenolpyruvate carboxykinase (ATP), conserved site")|refseq:NP_013023.3|mint:P10963 ensemblfungi:YKR097W(gene)|ensemblfungi:YKR097W_mRNA(transcript)|go:"GO:0004612"("phosphoenolpyruvate carboxykinase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|sgd:S000001805|interpro:IPR001272(Phosphoenolpyruvate carboxykinase, ATP-utilising)|interpro:IPR013035(Phosphoenolpyruvate carboxykinase, C-terminal)|interpro:IPR008210(Phosphoenolpyruvate carboxykinase, N-terminal)|interpro:IPR015994("Phosphoenolpyruvate carboxykinase (ATP), conserved site")|refseq:NP_013023.3|mint:P10963 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:67WkOy2lB17l/fXG2KVfQ+vQvnk559292 rogid:67WkOy2lB17l/fXG2KVfQ+vQvnk559292 intact-crc:E17F982794DD2774|rigid:BpwCrSdg9TSNNbJv72w18qSFoZc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10963 uniprotkb:P54783 intact:EBI-13770|uniprotkb:E9P963|ensemblfungi:YKR097W|uniprotkb:D6VXF8 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:pcka_yeast(display_long)|uniprotkb:PCK1(gene name)|psi-mi:PCK1(display_short)|uniprotkb:PEPC(gene name synonym)|uniprotkb:PPC1(gene name synonym)|uniprotkb:YKR097W(locus name) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316121|imex:IM-14275-202 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YKR097W(gene)|ensemblfungi:YKR097W_mRNA(transcript)|go:"GO:0004612"("phosphoenolpyruvate carboxykinase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|sgd:S000001805|interpro:IPR001272(Phosphoenolpyruvate carboxykinase, ATP-utilising)|interpro:IPR013035(Phosphoenolpyruvate carboxykinase, C-terminal)|interpro:IPR008210(Phosphoenolpyruvate carboxykinase, N-terminal)|interpro:IPR015994("Phosphoenolpyruvate carboxykinase (ATP), conserved site")|refseq:NP_013023.3|mint:P10963 go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:67WkOy2lB17l/fXG2KVfQ+vQvnk559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:DC6951418803FBD7|rigid:Ln8U9bi/t9y/mljgMkoFW2Hoook false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11075 uniprotkb:P32660 intact:EBI-16882|uniprotkb:Q03960|uniprotkb:Q04139|uniprotkb:D6VSF1|ensemblfungi:YDR170C intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W psi-mi:sec7_yeast(display_long)|uniprotkb:SEC7(gene name)|psi-mi:SEC7(display_short)|uniprotkb:YD9395.01C(orf name)|uniprotkb:YD9489.05C(orf name)|uniprotkb:YDR170C(locus name) psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316154|imex:IM-14275-205 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010454.3|ensemblfungi:YDR170C(gene)|ensemblfungi:YDR170C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005770"(late endosome)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0032012"(regulation of ARF protein signal transduction)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|rcsb pdb:4OIY|go:"GO:0015031"(protein transport)|sgd:S000002577|dip:DIP-830N|mint:P11075 sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) psi-mi:"MI:0469"(intact) crc64:02B2D370DD2E4661 crc64:3CC3FBA8ADDE8960 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BoKfHXfAHnYKyYGbglgZr/3djRw559292 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 intact-crc:1622BCCDD4EF33FD|rigid:9qg44MtYjiEGRhPL2lVRQrNh1kE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11075 uniprotkb:P13134 intact:EBI-16882|uniprotkb:Q03960|uniprotkb:Q04139|uniprotkb:D6VSF1|ensemblfungi:YDR170C intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5 psi-mi:sec7_yeast(display_long)|uniprotkb:SEC7(gene name)|psi-mi:SEC7(display_short)|uniprotkb:YD9395.01C(orf name)|uniprotkb:YD9489.05C(orf name)|uniprotkb:YDR170C(locus name) psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316143|imex:IM-14275-204 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010454.3|ensemblfungi:YDR170C(gene)|ensemblfungi:YDR170C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005770"(late endosome)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0032012"(regulation of ARF protein signal transduction)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|rcsb pdb:4OIY|go:"GO:0015031"(protein transport)|sgd:S000002577|dip:DIP-830N|mint:P11075 interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134 psi-mi:"MI:0469"(intact) crc64:02B2D370DD2E4661 crc64:5DCEEDADCF439C78 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BoKfHXfAHnYKyYGbglgZr/3djRw559292 rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292 intact-crc:8C317CA0CA07A62D|rigid:s0Da4apWxvi4xDxyn3sr7gtXLh8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11075 uniprotkb:P11075 intact:EBI-16882|uniprotkb:Q03960|uniprotkb:Q04139|uniprotkb:D6VSF1|ensemblfungi:YDR170C intact:EBI-16882|uniprotkb:Q03960|uniprotkb:Q04139|uniprotkb:D6VSF1|ensemblfungi:YDR170C psi-mi:sec7_yeast(display_long)|uniprotkb:SEC7(gene name)|psi-mi:SEC7(display_short)|uniprotkb:YD9395.01C(orf name)|uniprotkb:YD9489.05C(orf name)|uniprotkb:YDR170C(locus name) psi-mi:sec7_yeast(display_long)|uniprotkb:SEC7(gene name)|psi-mi:SEC7(display_short)|uniprotkb:YD9395.01C(orf name)|uniprotkb:YD9489.05C(orf name)|uniprotkb:YDR170C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316132|imex:IM-14275-203 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010454.3|ensemblfungi:YDR170C(gene)|ensemblfungi:YDR170C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005770"(late endosome)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0032012"(regulation of ARF protein signal transduction)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|rcsb pdb:4OIY|go:"GO:0015031"(protein transport)|sgd:S000002577|dip:DIP-830N|mint:P11075 refseq:NP_010454.3|ensemblfungi:YDR170C(gene)|ensemblfungi:YDR170C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005770"(late endosome)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0032012"(regulation of ARF protein signal transduction)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|rcsb pdb:4OIY|go:"GO:0015031"(protein transport)|sgd:S000002577|dip:DIP-830N|mint:P11075 psi-mi:"MI:0469"(intact) crc64:02B2D370DD2E4661 crc64:02B2D370DD2E4661 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BoKfHXfAHnYKyYGbglgZr/3djRw559292 rogid:BoKfHXfAHnYKyYGbglgZr/3djRw559292 intact-crc:96D96EAC0E5440BF|rigid:IL+Wtcb2yPx7tkxiKjxXJ8O5BCk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:P09620 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316198|imex:IM-14275-209 author score:86.47 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 - figure legend:tables S3 and S4|author-confidence:86.47|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:561B5CCF4878EA85|rigid:uK8ggexJwrl+0+QZZ39eir38WFc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11075 uniprotkb:Q12114 intact:EBI-16882|uniprotkb:Q03960|uniprotkb:Q04139|uniprotkb:D6VSF1|ensemblfungi:YDR170C intact:EBI-4640|uniprotkb:D6VYX2|ensemblfungi:YLR330W psi-mi:sec7_yeast(display_long)|uniprotkb:SEC7(gene name)|psi-mi:SEC7(display_short)|uniprotkb:YD9395.01C(orf name)|uniprotkb:YD9489.05C(orf name)|uniprotkb:YDR170C(locus name) psi-mi:chs5_yeast(display_long)|uniprotkb:CHS5(gene name)|psi-mi:CHS5(display_short)|uniprotkb:CAL3(gene name synonym)|uniprotkb:YLR330W(locus name)|uniprotkb:L8543.18(orf name)|uniprotkb:Protein CAL3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316187|imex:IM-14275-208 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010454.3|ensemblfungi:YDR170C(gene)|ensemblfungi:YDR170C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005770"(late endosome)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0032012"(regulation of ARF protein signal transduction)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|rcsb pdb:4OIY|go:"GO:0015031"(protein transport)|sgd:S000002577|dip:DIP-830N|mint:P11075 refseq:NP_013434.1|sgd:S000004322|dip:DIP-8073N|mint:Q12114|ensemblfungi:YLR330W(gene)|ensemblfungi:YLR330W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006039"(cell wall chitin catabolic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034044"(exomer complex)|go:"GO:0043332"(mating projection tip)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001357(BRCT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031669|interpro:IPR031673|interpro:IPR036116|interpro:IPR036420|rcsb pdb:4IN3|rcsb pdb:4WJW|rcsb pdb:4YG8 psi-mi:"MI:0469"(intact) crc64:02B2D370DD2E4661 crc64:FA92741B862814C2 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BoKfHXfAHnYKyYGbglgZr/3djRw559292 rogid:iHvfW3fNLv3HLj4Ihya1Vyt0X7I559292 intact-crc:C2A0B0566E18D1BF|rigid:xuXHJHGtkX3BSavZuslL0eNncgA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12057 uniprotkb:P11075 intact:EBI-29838|uniprotkb:D6W2G4|ensemblfungi:YOR104W intact:EBI-16882|uniprotkb:Q03960|uniprotkb:Q04139|uniprotkb:D6VSF1|ensemblfungi:YDR170C psi-mi:pin2_yeast(display_long)|uniprotkb:PIN2(gene name)|psi-mi:PIN2(display_short)|uniprotkb:YOR3214W(orf name)|uniprotkb:YOR104W(locus name) psi-mi:sec7_yeast(display_long)|uniprotkb:SEC7(gene name)|psi-mi:SEC7(display_short)|uniprotkb:YD9395.01C(orf name)|uniprotkb:YD9489.05C(orf name)|uniprotkb:YDR170C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316176|imex:IM-14275-207 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005630|refseq:NP_014747.1|dip:DIP-4459N|mint:Q12057|ensemblfungi:YOR104W(gene)|ensemblfungi:YOR104W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|interpro:IPR037504 refseq:NP_010454.3|ensemblfungi:YDR170C(gene)|ensemblfungi:YDR170C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005770"(late endosome)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0032012"(regulation of ARF protein signal transduction)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|rcsb pdb:4OIY|go:"GO:0015031"(protein transport)|sgd:S000002577|dip:DIP-830N|mint:P11075 psi-mi:"MI:0469"(intact) - crc64:02B2D370DD2E4661 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Zk6iUcpP++MEXuhKZ79TMOYQYqM559292 rogid:BoKfHXfAHnYKyYGbglgZr/3djRw559292 intact-crc:D84416A993B5C7CF|rigid:XQ2hQ/BQ8Rp8zJHQ4CcqZuJderI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11075 uniprotkb:P39524 intact:EBI-16882|uniprotkb:Q03960|uniprotkb:Q04139|uniprotkb:D6VSF1|ensemblfungi:YDR170C intact:EBI-3106|uniprotkb:D6VPJ2|ensemblfungi:YAL026C psi-mi:sec7_yeast(display_long)|uniprotkb:SEC7(gene name)|psi-mi:SEC7(display_short)|uniprotkb:YD9395.01C(orf name)|uniprotkb:YD9489.05C(orf name)|uniprotkb:YDR170C(locus name) psi-mi:atc3_yeast(display_long)|uniprotkb:DRS2(gene name)|psi-mi:DRS2(display_short)|uniprotkb:FUN38(orf name)|uniprotkb:YAL026C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316165|imex:IM-14275-206 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010454.3|ensemblfungi:YDR170C(gene)|ensemblfungi:YDR170C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005770"(late endosome)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0032012"(regulation of ARF protein signal transduction)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|rcsb pdb:4OIY|go:"GO:0015031"(protein transport)|sgd:S000002577|dip:DIP-830N|mint:P11075 refseq:NP_009376.2|sgd:S000000024|dip:DIP-2216N|mint:P39524|ensemblfungi:YAL026C(gene)|ensemblfungi:YAL026C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|go:"GO:1990530"(Cdc50p-Drs2p complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:6PSX|rcsb pdb:6PSY|rcsb pdb:6ROH|rcsb pdb:6ROI|rcsb pdb:6ROJ|rcsb pdb:7OH4|rcsb pdb:7OH5|rcsb pdb:7OH6|rcsb pdb:7OH7|reactome:R-SCE-6798695|reactome:R-SCE-936837 psi-mi:"MI:0469"(intact) crc64:02B2D370DD2E4661 crc64:5745B92901F8E1AE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BoKfHXfAHnYKyYGbglgZr/3djRw559292 rogid:qJ8uK7dznIqyjVwjbw/VGn5Bo+4559292 intact-crc:B170EDAFC587AE8A|rigid:8hnC8Ab/8SV6d8DNjNc9H62Pgz8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:P32465 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316231|imex:IM-14275-212 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 intact-crc:DADD240CB70CF7D4|rigid:qVxhnHVy8S3Uxpdd40BaQ4QH4Yg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19146 uniprotkb:P11076 intact:EBI-2820|uniprotkb:A2TBP3|uniprotkb:D6VRL1|ensemblfungi:YDL137W intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W psi-mi:arf2_yeast(display_long)|uniprotkb:ARF2(gene name)|psi-mi:ARF2(display_short)|uniprotkb:D2165(orf name)|uniprotkb:YDL137W(locus name) psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316220|imex:IM-14275-211 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010144.1|sgd:S000002296|dip:DIP-2215N|mint:P19146|ensemblfungi:YDL137W(gene)|ensemblfungi:YDL137W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:1MR3|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 psi-mi:"MI:0469"(intact) crc64:7E43FF792E8D64E8 crc64:796859026AC63CC0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I4V9cXleaZ2sAE2DXGKt8zpAPzw559292 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 intact-crc:84596D920ED302BD|rigid:AT1OwijMU0sHBxGzKEBnmNTCjC8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:P11076 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316209|imex:IM-14275-210 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 crc64:796859026AC63CC0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 intact-crc:851273CBA7C20A84|rigid:VBCfeD7q83udd5Bm8HWYgk9x2Ig false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:P39010 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316264|imex:IM-14275-215 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 intact-crc:BD602B7AD80CD1D8|rigid:rn54wm4nBxbzznxczuIVwLUUyog false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38142 uniprotkb:P11076 intact:EBI-21079|uniprotkb:D6VQN7|intact:EBI-2347460|uniprotkb:Q6B2Y5|ensemblfungi:YBR241C intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W psi-mi:yb91_yeast(display_long)|uniprotkb:YBR1625(orf name)|uniprotkb:YBR241C(locus name) psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316253|imex:IM-14275-214 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009800.1|sgd:S000000445|mint:P38142|dip:DIP-5363N|ensemblfungi:YBR241C(gene)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|reactome:R-SCE-189200|reactome:R-SCE-196836|reactome:R-SCE-422356|reactome:R-SCE-5653890|reactome:R-SCE-6798695|reactome:R-SCE-8981373|ensemblfungi:YBR241C_mRNA(transcript) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 psi-mi:"MI:0469"(intact) - crc64:796859026AC63CC0 figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:B0qgnhfd17hrDGLrJ21KY/FCzTQ559292 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 intact-crc:D6DA12C7975B4B87|rigid:xDY3XcMVoZw7o5Ju0/ChlQ0FbmE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:P38084 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-3414|uniprotkb:D6VQ67|ensemblfungi:YBR068C psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:bap2_yeast(display_long)|uniprotkb:Branched-chain amino-acid permease 2(gene name synonym)|uniprotkb:BAP2(gene name)|psi-mi:BAP2(display_short)|uniprotkb:YBR068C(locus name)|uniprotkb:YBR0629(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316242|imex:IM-14275-213 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 sgd:S000000272|refseq:NP_009624.4|dip:DIP-4910N|mint:P38084|ensemblfungi:YBR068C(gene)|ensemblfungi:YBR068C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015192"(L-phenylalanine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098713"(leucine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 crc64:B87FD6A7464E07F5 figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:7Fw7+M5mBikZBztHE2tSDpvBi/M559292 intact-crc:179927EFE06CD802|rigid:2w+YOX2w2T6pEklqoXIr4bvWTwc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46989 uniprotkb:P11076 intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316308|imex:IM-14275-219 author score:89.17 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 psi-mi:"MI:0469"(intact) - crc64:796859026AC63CC0 figure legend:tables S3 and S4|author-confidence:89.17|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 intact-crc:7724BB2BEE0163F5|rigid:CyCzbqzwBUQPwPEZ/IrxasfP3cs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:P43621 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-4876|uniprotkb:D6VTT4|ensemblfungi:YFR051C psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:copd_yeast(display_long)|uniprotkb:RET2(gene name)|psi-mi:RET2(display_short)|uniprotkb:YFR051C(locus name)|uniprotkb:Delta-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316297|imex:IM-14275-218 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 sgd:S000001947|refseq:NP_116709.3|dip:DIP-5255N|mint:P43621|ensemblfungi:YFR051C(gene)|ensemblfungi:YFR051C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|rcsb pdb:5FJW|rcsb pdb:5FJX|rcsb pdb:5FJZ|rcsb pdb:5FK0|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 crc64:AA730F046655EE5A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:auvjuT8ffm1R4P3mRKEIWAsynW0559292 intact-crc:F5D43E23892203C1|rigid:lBpUfke5EXo1z0mxtA5uZ8/8NDc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42838 uniprotkb:P11076 intact:EBI-28396|uniprotkb:D6W0M3|ensemblfungi:YNL323W intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W psi-mi:lem3_yeast(display_long)|uniprotkb:LEM3(gene name)|psi-mi:LEM3(display_short)|uniprotkb:BRE3(gene name synonym)|uniprotkb:Ro-sensitive 3(gene name synonym)|uniprotkb:Brefeldin-A sensitivity protein 3(gene name synonym)|uniprotkb:ROS3(gene name synonym)|uniprotkb:N0333(orf name)|uniprotkb:YNL323W(locus name) psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316286|imex:IM-14275-217 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014076.1|sgd:S000005267|dip:DIP-4598N|mint:P42838|ensemblfungi:YNL323W(gene)|ensemblfungi:YNL323W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044088"(regulation of vacuole organization)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0140331"(aminophospholipid translocation)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|rcsb pdb:7KY5|rcsb pdb:7KY7|rcsb pdb:7KY8|rcsb pdb:7KY9|rcsb pdb:7KYA|rcsb pdb:7KYB|rcsb pdb:7KYC|reactome:R-SCE-6798695 refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 psi-mi:"MI:0469"(intact) crc64:55BDA1F32251B4E6 crc64:796859026AC63CC0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YNU4U5F2bWdXZvJYQ9HK0iWX230559292 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 intact-crc:4028B83E7FBF8ED2|rigid:6y1XhiCBtYzfqk5ZhtN88MfoIjI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40474 uniprotkb:P11076 intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316275|imex:IM-14275-216 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 psi-mi:"MI:0469"(intact) - crc64:796859026AC63CC0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 intact-crc:2ECB082858E42067|rigid:GSmIzz4HMFS719fa3az0MEx63LA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:P54783 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316330|imex:IM-14275-221 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:8266C456C400290D|rigid:xrWLAk3n68VxUYiZhjz1lMfNqDs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:P53728 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-5444|uniprotkb:E9P900|uniprotkb:D6W1K2|ensemblfungi:YNR028W psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:cyp8_yeast(display_long)|uniprotkb:CPR8(gene name)|psi-mi:CPR8(display_short)|uniprotkb:YNR028W(locus name)|uniprotkb:N3255(orf name)|uniprotkb:Rotamase CYP8(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316319|imex:IM-14275-220 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 sgd:S000005311|refseq:NP_014425.3|dip:DIP-4261N|mint:P53728|ensemblfungi:YNR028W(gene)|ensemblfungi:YNR028W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR029000 psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:PWJO9W+2WFHhC6Fl3xoH0rw9a2w559292 intact-crc:C91B8CDCD7EB81E0|rigid:o0vS3z9ODMKUxUIMocfCDgeSKj0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06451 uniprotkb:P11076 intact:EBI-34275|uniprotkb:D6W4F2|ensemblfungi:YPR156C intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W psi-mi:tpo3_yeast(display_long)|uniprotkb:TPO3(gene name)|psi-mi:TPO3(display_short)|uniprotkb:P9584.7(orf name)|uniprotkb:YPR156C(locus name) psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316363|imex:IM-14275-224 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015482.1|sgd:S000006360|mint:Q06451|dip:DIP-3907N|ensemblfungi:YPR156C(gene)|ensemblfungi:YPR156C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 psi-mi:"MI:0469"(intact) crc64:D260ED161F800502 crc64:796859026AC63CC0 figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oVpx7Bjk/mK2Q7+/j05tX3gHw7k559292 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 intact-crc:2882D48B172BAE93|rigid:nGiheQwcByQ+zqPEkN+26ZoilAQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:Q03860 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316352|imex:IM-14275-223 author score:87.93 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:87.93|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:C25323BD703E5AE4|rigid:jEZn0i2X1B33yTriQ0xpafrZ/Ew false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:Q03687 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316341|imex:IM-14275-222 author score:96.38 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 - figure legend:tables S3 and S4|author-confidence:96.38|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 intact-crc:28222E920E5419E6|rigid:ch0MrGc8urJIzcfP7kG0AGeOTrU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:Q12270 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316396|imex:IM-14275-227 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:7976EA32F7F557F3|rigid:1r7glq/LkA7DOI1GQvK1rEh7Q94 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12016 uniprotkb:P11076 intact:EBI-29309|uniprotkb:D6W1T9|ensemblfungi:YOL129W intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W psi-mi:vps68_yeast(display_long)|uniprotkb:YOL129W(locus name)|uniprotkb:VPS68(gene name)|psi-mi:VPS68(display_short) psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316385|imex:IM-14275-226 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014512.1|sgd:S000005489|dip:DIP-1732N|mint:Q12016|ensemblfungi:YOL129W(gene)|ensemblfungi:YOL129W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0034424"(Vps55/Vps68 complex)|interpro:IPR007919(Protein of unknown function UPF0220) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 psi-mi:"MI:0469"(intact) crc64:4B21C846AB3BA2A7 crc64:796859026AC63CC0 figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I6sUyfNcLBsFG3OtDUfEqohxLB4559292 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 intact-crc:3184859EE17CE024|rigid:Rv4cY41itj3Pq5PBKBRgVlHJrK8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:Q08280 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-35858|uniprotkb:Q6B229|uniprotkb:D6W1T2|ensemblfungi:YOL137W psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:bsc6_yeast(display_long)|uniprotkb:YOL137W(locus name)|uniprotkb:BSC6(gene name)|psi-mi:BSC6(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316374|imex:IM-14275-225 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 refseq:NP_014504.1|sgd:S000005497|mint:Q08280|dip:DIP-4683N|ensemblfungi:YOL137W(gene)|ensemblfungi:YOL137W_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:WVYZke8YJvNcS4D9bUnthAFdq3A559292 intact-crc:267E9A49D1D54ED8|rigid:CxriFZHqa9vqDoUJIEm2AYPtPM0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29366 uniprotkb:P11433 intact:EBI-3508|uniprotkb:D6VQJ6|ensemblfungi:YBR200W intact:EBI-4220|uniprotkb:D6VPH5|ensemblfungi:YAL041W psi-mi:bem1_yeast(display_long)|uniprotkb:Suppressor of RHO3 protein 1(gene name synonym)|uniprotkb:BEM1(gene name)|psi-mi:BEM1(display_short)|uniprotkb:SRO1(gene name synonym)|uniprotkb:YBR200W(locus name)|uniprotkb:YBR1412(orf name) psi-mi:cdc24_yeast(display_long)|uniprotkb:CLS4(gene name synonym)|uniprotkb:YAL041W(locus name)|uniprotkb:CDC24(gene name)|psi-mi:CDC24(display_short)|uniprotkb:Calcium regulatory protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316418|imex:IM-14275-229 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000404|refseq:NP_009759.3|dip:DIP-688N|mint:P29366|ensemblfungi:YBR200W(gene)|ensemblfungi:YBR200W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030427"(site of polarized growth)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR030507|interpro:IPR035548|interpro:IPR035549|interpro:IPR035550|interpro:IPR036028|interpro:IPR036871|rcsb pdb:1IP9|rcsb pdb:1IPG|rcsb pdb:2CZO|rcsb pdb:2KFK|rcsb pdb:2RQV|rcsb pdb:2RQW|rcsb pdb:2V6V|reactome:R-SCE-5668599 refseq:NP_009359.1|sgd:S000000039|dip:DIP-2228N|mint:P11433|ensemblfungi:YAL041W(gene)|ensemblfungi:YAL041W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000935"(division septum)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043577"(chemotropism)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010481(CDC24 calponin)|interpro:IPR033511|interpro:IPR035899|interpro:IPR036872|rcsb pdb:1PQS|rcsb pdb:1Q1O|rcsb pdb:1TZ1|rcsb pdb:2KFJ|rcsb pdb:2KFK psi-mi:"MI:0469"(intact) crc64:FB6C525AE9A19181 crc64:856BCAF4EB0A67D1 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Fq7WxTviE31ivPWGJoZO5DsUcdg559292 rogid:Q9eflcLn4oOOeRZ4tTjHrPguDUc559292 intact-crc:994DE513EE67564E|rigid:3DWpBSdcUcxdkrnQitEqEpXyPO4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:Q3E756 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-2044812|uniprotkb:D6VPX0|ensemblfungi:YBL029C-A psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:yb029_yeast(display_long)|uniprotkb:YBL029C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316407|imex:IM-14275-228 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 sgd:S000007591|refseq:NP_076874.1|mint:Q3E756|ensemblfungi:YBL029C-A(gene)|ensemblfungi:YBL029C-A_mRNA(transcript)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 - figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:Y9LDkESr65DK5SLFNTw1dBKeqPc559292 intact-crc:218E75B40A21C707|rigid:VIOvKlzySRakGG9sBjoIU7SgsJo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11632 uniprotkb:Q12692 intact:EBI-12019|ensemblfungi:YPR052C|uniprotkb:D6W459 intact:EBI-8080|uniprotkb:D6W255|ensemblfungi:YOL012C psi-mi:nhp6a_yeast(display_long)|uniprotkb:NHP6A(gene name)|psi-mi:NHP6A(display_short)|uniprotkb:NHPA(gene name synonym)|uniprotkb:YPR052C(locus name)|uniprotkb:YP9499.09C(orf name) psi-mi:h2az_yeast(display_long)|uniprotkb:HTZ1(gene name)|psi-mi:HTZ1(display_short)|uniprotkb:H2AZ(gene name synonym)|uniprotkb:YOL012C(locus name)|uniprotkb:HTA3(gene name synonym)|uniprotkb:O2345(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316462|imex:IM-14275-233 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPR052C(gene)|ensemblfungi:YPR052C_mRNA(transcript)|go:"GO:0001195"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase III promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006298"(mismatch repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070898"(RNA polymerase III preinitiation complex assembly)|rcsb pdb:1CG7|rcsb pdb:1J5N|rcsb pdb:1LWM|reactome:R-SCE-140342|reactome:R-SCE-5620971|reactome:R-SCE-5686938|reactome:R-SCE-6798695|go:"GO:0034724"(DNA replication-independent chromatin organization)|refseq:NP_015377.1|sgd:S000006256|interpro:IPR009071(High mobility group box, HMG)|mint:P11632|interpro:IPR036910 refseq:NP_014631.1|sgd:S000005372|mint:Q12692|dip:DIP-1381N|ensemblfungi:YOL012C(gene)|ensemblfungi:YOL012C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006342"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:2FSB|rcsb pdb:2JSS|rcsb pdb:4M6B|rcsb pdb:5J9Q|rcsb pdb:6AE8|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) - crc64:1D8FCEE3C8A504E7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fbls09qQTu0Jt8gk8qhtEvOFYAI559292 rogid:WNtmWZ+w+lXKNqAqIp0T4u28siw559292 intact-crc:B99A9AEB927EEFC0|rigid:o2TUB65wRwijhzeDcMNZVYa2Jcg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11632 uniprotkb:Q01080 intact:EBI-12019|ensemblfungi:YPR052C|uniprotkb:D6W459 intact:EBI-15741|uniprotkb:D6W0U5|ensemblfungi:YNL248C psi-mi:nhp6a_yeast(display_long)|uniprotkb:NHP6A(gene name)|psi-mi:NHP6A(display_short)|uniprotkb:NHPA(gene name synonym)|uniprotkb:YPR052C(locus name)|uniprotkb:YP9499.09C(orf name) psi-mi:rpa49_yeast(display_long)|uniprotkb:RPA49(gene name)|psi-mi:RPA49(display_short)|uniprotkb:RRN13(gene name synonym)|uniprotkb:YNL248C(locus name)|uniprotkb:N0880(orf name)|uniprotkb:DNA-directed RNA polymerase I 49 kDa polypeptide(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316451|imex:IM-14275-232 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPR052C(gene)|ensemblfungi:YPR052C_mRNA(transcript)|go:"GO:0001195"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase III promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006298"(mismatch repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070898"(RNA polymerase III preinitiation complex assembly)|rcsb pdb:1CG7|rcsb pdb:1J5N|rcsb pdb:1LWM|reactome:R-SCE-140342|reactome:R-SCE-5620971|reactome:R-SCE-5686938|reactome:R-SCE-6798695|go:"GO:0034724"(DNA replication-independent chromatin organization)|refseq:NP_015377.1|sgd:S000006256|interpro:IPR009071(High mobility group box, HMG)|mint:P11632|interpro:IPR036910 refseq:NP_014151.1|sgd:S000005192|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0008361"(regulation of cell size)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR009668(RNA polymerase I associated factor, A49-like)|rcsb pdb:3NFH|rcsb pdb:3NFI|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|ensemblfungi:YNL248C(gene)|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|ensemblfungi:YNL248C_mRNA(transcript)|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|go:"GO:0001054"(RNA polymerase I activity)|rcsb pdb:6H67|rcsb pdb:6H68|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|rcsb pdb:6HKO|rcsb pdb:6RQH|dip:DIP-6577N|mint:Q01080 psi-mi:"MI:0469"(intact) - crc64:3D9BF05440D26021 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fbls09qQTu0Jt8gk8qhtEvOFYAI559292 rogid:B7Nabi651A5fAilRf/0F2GHps/U559292 intact-crc:D57EB88B51C31A46|rigid:QCgHC/UQlWNq1TJvUkWM/71hlCs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53551 uniprotkb:P11632 intact:EBI-8064|uniprotkb:Q6Q5R6|uniprotkb:D6W3P0|ensemblfungi:YPL127C intact:EBI-12019|ensemblfungi:YPR052C|uniprotkb:D6W459 psi-mi:h1_yeast(display_long)|uniprotkb:HHO1(gene name)|psi-mi:HHO1(display_short)|uniprotkb:LPI17C(orf name)|uniprotkb:YPL127C(locus name) psi-mi:nhp6a_yeast(display_long)|uniprotkb:NHP6A(gene name)|psi-mi:NHP6A(display_short)|uniprotkb:NHPA(gene name synonym)|uniprotkb:YPR052C(locus name)|uniprotkb:YP9499.09C(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316440|imex:IM-14275-231 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015198.1|sgd:S000006048|mint:P53551|dip:DIP-6587N|ensemblfungi:YPL127C(gene)|ensemblfungi:YPL127C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0097100"(supercoiled DNA binding)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1UHM|rcsb pdb:1USS|rcsb pdb:1UST|rcsb pdb:1YQA ensemblfungi:YPR052C(gene)|ensemblfungi:YPR052C_mRNA(transcript)|go:"GO:0001195"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase III promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006298"(mismatch repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070898"(RNA polymerase III preinitiation complex assembly)|rcsb pdb:1CG7|rcsb pdb:1J5N|rcsb pdb:1LWM|reactome:R-SCE-140342|reactome:R-SCE-5620971|reactome:R-SCE-5686938|reactome:R-SCE-6798695|go:"GO:0034724"(DNA replication-independent chromatin organization)|refseq:NP_015377.1|sgd:S000006256|interpro:IPR009071(High mobility group box, HMG)|mint:P11632|interpro:IPR036910 psi-mi:"MI:0469"(intact) crc64:B0C53AC186E49F96 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dPMYSAq1Cr7pfGGNgb3GDp3LnsQ559292 rogid:fbls09qQTu0Jt8gk8qhtEvOFYAI559292 intact-crc:DCB1089ADE00A31C|rigid:KHOQ2s3L67ntmQwKv2KPTfXAnyA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11632 uniprotkb:P20434 intact:EBI-12019|ensemblfungi:YPR052C|uniprotkb:D6W459 intact:EBI-15781|uniprotkb:Q02121|ensemblfungi:YBR154C|uniprotkb:D6VQE9 psi-mi:nhp6a_yeast(display_long)|uniprotkb:NHP6A(gene name)|psi-mi:NHP6A(display_short)|uniprotkb:NHPA(gene name synonym)|uniprotkb:YPR052C(locus name)|uniprotkb:YP9499.09C(orf name) psi-mi:rpab1_yeast(display_long)|uniprotkb:RPB5(gene name)|psi-mi:RPB5(display_short)|uniprotkb:YBR154C(locus name)|uniprotkb:YBR1204(orf name)|uniprotkb:RPA7(gene name synonym)|uniprotkb:RPC9(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide(gene name synonym)|uniprotkb:ABC27(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316429|imex:IM-14275-230 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPR052C(gene)|ensemblfungi:YPR052C_mRNA(transcript)|go:"GO:0001195"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase III promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006298"(mismatch repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070898"(RNA polymerase III preinitiation complex assembly)|rcsb pdb:1CG7|rcsb pdb:1J5N|rcsb pdb:1LWM|reactome:R-SCE-140342|reactome:R-SCE-5620971|reactome:R-SCE-5686938|reactome:R-SCE-6798695|go:"GO:0034724"(DNA replication-independent chromatin organization)|refseq:NP_015377.1|sgd:S000006256|interpro:IPR009071(High mobility group box, HMG)|mint:P11632|interpro:IPR036910 rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|rcsb pdb:1WCM|rcsb pdb:1Y1V|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|rcsb pdb:2B63|rcsb pdb:2B8K|interpro:IPR020608|interpro:IPR020609|rcsb pdb:2E2H|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:1DZF|rcsb pdb:1I3Q|rcsb pdb:2E2I|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:5M5Y|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6H67|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:2E2J|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|ensemblfungi:YBR154C(gene)|ensemblfungi:YBR154C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4V1M|rcsb pdb:2JA5|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2JA6|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:2JA7|rcsb pdb:3GTG|rcsb pdb:2JA8|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:2NVQ|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4YM7|rcsb pdb:5C3E|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5G5L|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6H68|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|rcsb pdb:6UQ2|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-77075|reactome:R-SCE-9018519|refseq:NP_009712.1|sgd:S000000358|dip:DIP-71N|mint:P20434 psi-mi:"MI:0469"(intact) - crc64:2A15F7114D69D829 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fbls09qQTu0Jt8gk8qhtEvOFYAI559292 rogid:j/jAJ2fXWf4ebK1aWTWrKERGUpM559292 intact-crc:803329F1E6EDC3B6|rigid:Su1Tp/cEW9W4RrGbrOcYCJKDx8k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11986 uniprotkb:P17555 intact:EBI-9257|ensemblfungi:YJL153C|uniprotkb:D6VW34 intact:EBI-4024|uniprotkb:D6W144|ensemblfungi:YNL138W psi-mi:ino1_yeast(display_long)|uniprotkb:INO1(gene name)|psi-mi:INO1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym)|uniprotkb:J0610(orf name)|uniprotkb:YJL153C(locus name) psi-mi:cap_yeast(display_long)|uniprotkb:SRV2(gene name)|psi-mi:SRV2(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:YNL138W(locus name)|uniprotkb:N1210(orf name)|uniprotkb:N1838(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316495|imex:IM-14275-236 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1P1K|ensemblfungi:YJL153C(gene)|ensemblfungi:YJL153C_mRNA(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|rcsb pdb:1JKF|rcsb pdb:1JKI|rcsb pdb:1LA2|rcsb pdb:1P1F|rcsb pdb:1P1H|rcsb pdb:1P1I|rcsb pdb:1P1J|rcsb pdb:1RM0|reactome:R-SCE-1855183|refseq:NP_012382.2|sgd:S000003689|dip:DIP-5687N|mint:P11986 refseq:NP_014261.1|sgd:S000005082|dip:DIP-77N|ensemblfungi:YNL138W(gene)|ensemblfungi:YNL138W_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007265"(Ras protein signal transduction)|mint:P17555|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0051014"(actin filament severing)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|rcsb pdb:1K4Z|rcsb pdb:1KQ5|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) crc64:282E2AE5D156289D crc64:0EB4D41205E2D464 figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3OB3q28fOVxXSBMwMpLe2c1g8p8559292 rogid:3Fs9g+L5RnbkqYThVpOvSFrZoJ8559292 intact-crc:BA4AB68B06C99082|rigid:eWOpo2CA+UJMW1HQvk1y8SX/7u4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11986 uniprotkb:P11986 intact:EBI-9257|ensemblfungi:YJL153C|uniprotkb:D6VW34 intact:EBI-9257|ensemblfungi:YJL153C|uniprotkb:D6VW34 psi-mi:ino1_yeast(display_long)|uniprotkb:INO1(gene name)|psi-mi:INO1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym)|uniprotkb:J0610(orf name)|uniprotkb:YJL153C(locus name) psi-mi:ino1_yeast(display_long)|uniprotkb:INO1(gene name)|psi-mi:INO1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym)|uniprotkb:J0610(orf name)|uniprotkb:YJL153C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316484|imex:IM-14275-235 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1P1K|ensemblfungi:YJL153C(gene)|ensemblfungi:YJL153C_mRNA(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|rcsb pdb:1JKF|rcsb pdb:1JKI|rcsb pdb:1LA2|rcsb pdb:1P1F|rcsb pdb:1P1H|rcsb pdb:1P1I|rcsb pdb:1P1J|rcsb pdb:1RM0|reactome:R-SCE-1855183|refseq:NP_012382.2|sgd:S000003689|dip:DIP-5687N|mint:P11986 rcsb pdb:1P1K|ensemblfungi:YJL153C(gene)|ensemblfungi:YJL153C_mRNA(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|rcsb pdb:1JKF|rcsb pdb:1JKI|rcsb pdb:1LA2|rcsb pdb:1P1F|rcsb pdb:1P1H|rcsb pdb:1P1I|rcsb pdb:1P1J|rcsb pdb:1RM0|reactome:R-SCE-1855183|refseq:NP_012382.2|sgd:S000003689|dip:DIP-5687N|mint:P11986 psi-mi:"MI:0469"(intact) crc64:282E2AE5D156289D crc64:282E2AE5D156289D figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3OB3q28fOVxXSBMwMpLe2c1g8p8559292 rogid:3OB3q28fOVxXSBMwMpLe2c1g8p8559292 intact-crc:B210ED020CFB9905|rigid:KHgpiLmzD03gHBOS976dWVJZCzA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07170 uniprotkb:P11986 intact:EBI-9447|ensemblfungi:YDR226W|uniprotkb:D6VSK8|uniprotkb:Q6Q539 intact:EBI-9257|ensemblfungi:YJL153C|uniprotkb:D6VW34 psi-mi:kad2_yeast(display_long)|uniprotkb:AKY(gene name synonym)|uniprotkb:AKY1(gene name synonym)|uniprotkb:AKY2(gene name synonym)|uniprotkb:ADK1(gene name)|psi-mi:ADK1(display_short)|uniprotkb:Adenylate kinase cytosolic and mitochondrial(gene name synonym)|uniprotkb:ATP-AMP transphosphorylase(gene name synonym)|uniprotkb:"ATP:AMP phosphotransferase"(gene name synonym)|uniprotkb:Adenylate monophosphate kinase(gene name synonym)|uniprotkb:YD9934.11(orf name)|uniprotkb:YDR226W(locus name) psi-mi:ino1_yeast(display_long)|uniprotkb:INO1(gene name)|psi-mi:INO1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym)|uniprotkb:J0610(orf name)|uniprotkb:YJL153C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316473|imex:IM-14275-234 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR226W(gene)|ensemblfungi:YDR226W_mRNA(transcript)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006172"(ADP biosynthetic process)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046034"(ATP metabolic process)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006259(Adenylate kinase, subfamily)|interpro:IPR007862(Adenylate kinase, zinc-finger lid region)|interpro:IPR027417|interpro:IPR028587|interpro:IPR033690|rcsb pdb:1AKY|rcsb pdb:1DVR|rcsb pdb:2AKY|reactome:R-SCE-499943|rcsb pdb:3AKY|refseq:NP_010512.1|sgd:S000002634|mint:P07170|dip:DIP-5129N rcsb pdb:1P1K|ensemblfungi:YJL153C(gene)|ensemblfungi:YJL153C_mRNA(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|rcsb pdb:1JKF|rcsb pdb:1JKI|rcsb pdb:1LA2|rcsb pdb:1P1F|rcsb pdb:1P1H|rcsb pdb:1P1I|rcsb pdb:1P1J|rcsb pdb:1RM0|reactome:R-SCE-1855183|refseq:NP_012382.2|sgd:S000003689|dip:DIP-5687N|mint:P11986 psi-mi:"MI:0469"(intact) crc64:FE566FD8015907CE crc64:282E2AE5D156289D figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:G7pDmrl28ukuAmoX2EjGIKcQy/M559292 rogid:3OB3q28fOVxXSBMwMpLe2c1g8p8559292 intact-crc:C63F35F8CE5FAC4B|rigid:APvB5+kJ7wQQt6AHkVR5WCLoGas false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23542 uniprotkb:P11986 intact:EBI-2002|uniprotkb:D6VY29|ensemblfungi:YLR027C intact:EBI-9257|ensemblfungi:YJL153C|uniprotkb:D6VW34 psi-mi:aatc_yeast(display_long)|uniprotkb:AAT2(gene name)|psi-mi:AAT2(display_short)|uniprotkb:YLR027C(locus name)|uniprotkb:ASP5(gene name synonym)|uniprotkb:L1746(orf name)|uniprotkb:Transaminase A(gene name synonym) psi-mi:ino1_yeast(display_long)|uniprotkb:INO1(gene name)|psi-mi:INO1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym)|uniprotkb:J0610(orf name)|uniprotkb:YJL153C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316517|imex:IM-14275-238 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013127.2|sgd:S000004017|dip:DIP-2897N|mint:P23542|go:"GO:0019266"(asparagine biosynthetic process from oxaloacetate)|go:"GO:0030170"(pyridoxal phosphate binding)|interpro:IPR000796(Aspartate/other aminotransferase)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:1YAA|reactome:R-SCE-70263|reactome:R-SCE-8963693|ensemblfungi:YLR027C(gene)|ensemblfungi:YLR027C_mRNA(transcript)|go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0006532"(aspartate biosynthetic process)|go:"GO:0006536"(glutamate metabolic process) rcsb pdb:1P1K|ensemblfungi:YJL153C(gene)|ensemblfungi:YJL153C_mRNA(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|rcsb pdb:1JKF|rcsb pdb:1JKI|rcsb pdb:1LA2|rcsb pdb:1P1F|rcsb pdb:1P1H|rcsb pdb:1P1I|rcsb pdb:1P1J|rcsb pdb:1RM0|reactome:R-SCE-1855183|refseq:NP_012382.2|sgd:S000003689|dip:DIP-5687N|mint:P11986 psi-mi:"MI:0469"(intact) crc64:D25F40F6C6DD2B33 crc64:282E2AE5D156289D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:eNypS723YWwMMuWVVoTnidvQuaA559292 rogid:3OB3q28fOVxXSBMwMpLe2c1g8p8559292 intact-crc:89F7BF5FD5E67A8F|rigid:N+nVADesJ2WIFFwXq+mzv0tS5bk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11986 uniprotkb:P22137 intact:EBI-9257|ensemblfungi:YJL153C|uniprotkb:D6VW34 intact:EBI-4766|uniprotkb:D6VTU9|ensemblfungi:YGL206C psi-mi:ino1_yeast(display_long)|uniprotkb:INO1(gene name)|psi-mi:INO1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym)|uniprotkb:J0610(orf name)|uniprotkb:YJL153C(locus name) psi-mi:clh_yeast(display_long)|uniprotkb:CHC1(gene name)|psi-mi:CHC1(display_short)|uniprotkb:YGL206C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316506|imex:IM-14275-237 author score:99.26 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1P1K|ensemblfungi:YJL153C(gene)|ensemblfungi:YJL153C_mRNA(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|rcsb pdb:1JKF|rcsb pdb:1JKI|rcsb pdb:1LA2|rcsb pdb:1P1F|rcsb pdb:1P1H|rcsb pdb:1P1I|rcsb pdb:1P1J|rcsb pdb:1RM0|reactome:R-SCE-1855183|refseq:NP_012382.2|sgd:S000003689|dip:DIP-5687N|mint:P11986 refseq:NP_011309.1|sgd:S000003174|dip:DIP-2279N|mint:P22137|ensemblfungi:YGL206C(gene)|ensemblfungi:YGL206C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0071439"(clathrin complex)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-432720|reactome:R-SCE-437239|reactome:R-SCE-8856828|reactome:R-SCE-8866427|reactome:R-SCE-8964038 psi-mi:"MI:0469"(intact) crc64:282E2AE5D156289D crc64:622F3083DF2FE315 figure legend:tables S3 and S4|author-confidence:99.26|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3OB3q28fOVxXSBMwMpLe2c1g8p8559292 rogid:SAN6H3nVFozXZyTiRLaljMcIKIA559292 intact-crc:8CCB3B0B00A921E7|rigid:5xE1vw4/qPJ4sG1tXsXVBlhwLGE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32610 uniprotkb:P11986 intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W intact:EBI-9257|ensemblfungi:YJL153C|uniprotkb:D6VW34 psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym) psi-mi:ino1_yeast(display_long)|uniprotkb:INO1(gene name)|psi-mi:INO1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym)|uniprotkb:J0610(orf name)|uniprotkb:YJL153C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316550|imex:IM-14275-241 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610 rcsb pdb:1P1K|ensemblfungi:YJL153C(gene)|ensemblfungi:YJL153C_mRNA(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|rcsb pdb:1JKF|rcsb pdb:1JKI|rcsb pdb:1LA2|rcsb pdb:1P1F|rcsb pdb:1P1H|rcsb pdb:1P1I|rcsb pdb:1P1J|rcsb pdb:1RM0|reactome:R-SCE-1855183|refseq:NP_012382.2|sgd:S000003689|dip:DIP-5687N|mint:P11986 psi-mi:"MI:0469"(intact) crc64:FDE93E1FAF0AEC5B crc64:282E2AE5D156289D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292 rogid:3OB3q28fOVxXSBMwMpLe2c1g8p8559292 intact-crc:2D07FAF1DB64A01E|rigid:d4xg9mf5IwZ15MHuv4tGMDoReZo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32324 uniprotkb:P11986 intact:EBI-6333|uniprotkb:Q6JEF7|uniprotkb:D6VT19|ensemblfungi:YDR385W|ensemblfungi:YOR133W intact:EBI-9257|ensemblfungi:YJL153C|uniprotkb:D6VW34 psi-mi:ef2_yeast(display_long)|uniprotkb:EFT1(gene name)|psi-mi:EFT1(display_short)|uniprotkb:YOR133W(locus name)|uniprotkb:O3317(orf name)|uniprotkb:YOR3317W(orf name)|uniprotkb:EFT2(gene name)|psi-mi:EFT2(display_short)|uniprotkb:YDR385W(locus name)|uniprotkb:Translation elongation factor 2(gene name synonym)|uniprotkb:Eukaryotic elongation factor 2(gene name synonym)|uniprotkb:Ribosomal translocase(gene name synonym) psi-mi:ino1_yeast(display_long)|uniprotkb:INO1(gene name)|psi-mi:INO1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym)|uniprotkb:J0610(orf name)|uniprotkb:YJL153C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316539|imex:IM-14275-240 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010673.1|refseq:NP_014776.1|sgd:S000005659|sgd:S000002793|ensemblfungi:YDR385W(gene)|ensemblfungi:YDR385W_mRNA(transcript)|ensemblfungi:YOR133W(gene)|ensemblfungi:YOR133W_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0019843"(rRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0051087"(chaperone binding)|go:"GO:1990145"(maintenance of translational fidelity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|mint:P32324|dip:DIP-4911N|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|rcsb pdb:1N0U|rcsb pdb:1N0V|rcsb pdb:1U2R|rcsb pdb:1ZM2|rcsb pdb:1ZM3|rcsb pdb:1ZM4|rcsb pdb:1ZM9|rcsb pdb:2E1R|rcsb pdb:2NPF|rcsb pdb:2P8W|rcsb pdb:2P8X|rcsb pdb:2P8Y|rcsb pdb:2P8Z|rcsb pdb:2ZIT|rcsb pdb:3B78|rcsb pdb:3B82|rcsb pdb:3B8H|rcsb pdb:3DNY|rcsb pdb:4V4B|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|reactome:R-SCE-156902|reactome:R-SCE-5358493|reactome:R-SCE-6798695 rcsb pdb:1P1K|ensemblfungi:YJL153C(gene)|ensemblfungi:YJL153C_mRNA(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|rcsb pdb:1JKF|rcsb pdb:1JKI|rcsb pdb:1LA2|rcsb pdb:1P1F|rcsb pdb:1P1H|rcsb pdb:1P1I|rcsb pdb:1P1J|rcsb pdb:1RM0|reactome:R-SCE-1855183|refseq:NP_012382.2|sgd:S000003689|dip:DIP-5687N|mint:P11986 psi-mi:"MI:0469"(intact) crc64:FD2F8073CB9B66AA crc64:282E2AE5D156289D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mlyt9YKZrGhGbsSlvxNJ0p1C67I559292 rogid:3OB3q28fOVxXSBMwMpLe2c1g8p8559292 intact-crc:22173C290165778A|rigid:Oso9R/gyq0Elibg9whCGqt3Hz0Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24276 uniprotkb:P11986 intact:EBI-18153|uniprotkb:D6VSS2|ensemblfungi:YDR293C intact:EBI-9257|ensemblfungi:YJL153C|uniprotkb:D6VW34 psi-mi:ssd1_yeast(display_long)|uniprotkb:SSD1(gene name)|psi-mi:SSD1(display_short)|uniprotkb:CLA1(gene name synonym)|uniprotkb:RLD1(gene name synonym)|uniprotkb:SRK1(gene name synonym)|uniprotkb:YDR293C(locus name)|uniprotkb:D9819.4(orf name)|uniprotkb:Protein SRK1(gene name synonym) psi-mi:ino1_yeast(display_long)|uniprotkb:INO1(gene name)|psi-mi:INO1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym)|uniprotkb:J0610(orf name)|uniprotkb:YJL153C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316528|imex:IM-14275-239 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010579.1|sgd:S000002701|ensemblfungi:YDR293C(gene)|ensemblfungi:YDR293C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051301"(cell division)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR041093|interpro:IPR041505|rcsb pdb:5NCL|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007049"(cell cycle)|dip:DIP-6449N|mint:P24276 rcsb pdb:1P1K|ensemblfungi:YJL153C(gene)|ensemblfungi:YJL153C_mRNA(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|rcsb pdb:1JKF|rcsb pdb:1JKI|rcsb pdb:1LA2|rcsb pdb:1P1F|rcsb pdb:1P1H|rcsb pdb:1P1I|rcsb pdb:1P1J|rcsb pdb:1RM0|reactome:R-SCE-1855183|refseq:NP_012382.2|sgd:S000003689|dip:DIP-5687N|mint:P11986 psi-mi:"MI:0469"(intact) crc64:3D50FD6838ECA514 crc64:282E2AE5D156289D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:myt8+lnu2/li6TuGiM5GBfMtUiw559292 rogid:3OB3q28fOVxXSBMwMpLe2c1g8p8559292 intact-crc:C679706B369A140A|rigid:wB6WfbG4Rq1nwCIJ1fF2JpnxM+E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11986 uniprotkb:P38009 intact:EBI-9257|ensemblfungi:YJL153C|uniprotkb:D6VW34 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 psi-mi:ino1_yeast(display_long)|uniprotkb:INO1(gene name)|psi-mi:INO1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym)|uniprotkb:J0610(orf name)|uniprotkb:YJL153C(locus name) psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316561|imex:IM-14275-242 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1P1K|ensemblfungi:YJL153C(gene)|ensemblfungi:YJL153C_mRNA(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|rcsb pdb:1JKF|rcsb pdb:1JKI|rcsb pdb:1LA2|rcsb pdb:1P1F|rcsb pdb:1P1H|rcsb pdb:1P1I|rcsb pdb:1P1J|rcsb pdb:1RM0|reactome:R-SCE-1855183|refseq:NP_012382.2|sgd:S000003689|dip:DIP-5687N|mint:P11986 refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N psi-mi:"MI:0469"(intact) crc64:282E2AE5D156289D crc64:8ABA71761B512242 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3OB3q28fOVxXSBMwMpLe2c1g8p8559292 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 intact-crc:FF4AF839778C59EE|rigid:VkFEfTyTnmS8NZmg0h/dt6ddTdM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41811 uniprotkb:P11986 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W intact:EBI-9257|ensemblfungi:YJL153C|uniprotkb:D6VW34 psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:ino1_yeast(display_long)|uniprotkb:INO1(gene name)|psi-mi:INO1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym)|uniprotkb:J0610(orf name)|uniprotkb:YJL153C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316572|imex:IM-14275-243 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 rcsb pdb:1P1K|ensemblfungi:YJL153C(gene)|ensemblfungi:YJL153C_mRNA(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|rcsb pdb:1JKF|rcsb pdb:1JKI|rcsb pdb:1LA2|rcsb pdb:1P1F|rcsb pdb:1P1H|rcsb pdb:1P1I|rcsb pdb:1P1J|rcsb pdb:1RM0|reactome:R-SCE-1855183|refseq:NP_012382.2|sgd:S000003689|dip:DIP-5687N|mint:P11986 psi-mi:"MI:0469"(intact) crc64:6A5E50BBEB02CB58 crc64:282E2AE5D156289D figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 rogid:3OB3q28fOVxXSBMwMpLe2c1g8p8559292 intact-crc:1E9DB00FC847564D|rigid:cEuL7OdVxvAtxANOh/aE8g6we3A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P12684 uniprotkb:P12683 intact:EBI-8384|uniprotkb:E9P8X3|uniprotkb:D6VZ84|ensemblfungi:YLR450W intact:EBI-8377|uniprotkb:D6W0K8|ensemblfungi:YML075C psi-mi:hmdh2_yeast(display_long)|uniprotkb:L9324.2(orf name)|uniprotkb:YLR450W(locus name)|uniprotkb:HMG2(gene name)|psi-mi:HMG2(display_short) psi-mi:hmdh1_yeast(display_long)|uniprotkb:YML075C(locus name)|uniprotkb:HMG1(gene name)|psi-mi:HMG1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316616|imex:IM-14275-247 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013555.1|sgd:S000004442|mint:P12684|dip:DIP-6277N|ensemblfungi:YLR450W(gene)|ensemblfungi:YLR450W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005635"(nuclear envelope)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0034399"(nuclear periphery)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|interpro:IPR025583 refseq:NP_013636.1|sgd:S000004540|mint:P12683|dip:DIP-4529N|ensemblfungi:YML075C(gene)|ensemblfungi:YML075C_mRNA(transcript)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005635"(nuclear envelope)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0019287"(isopentenyl diphosphate biosynthetic process, mevalonate pathway)|go:"GO:0034399"(nuclear periphery)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|interpro:IPR025583|reactome:R-SCE-191273 psi-mi:"MI:0469"(intact) crc64:1FD9DCD3AC01B15E - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6q1hM5csy4DSYUsSGyTr8M6b9r0559292 rogid:S+uIZsMovFNW2+PxvV7m76Jbh+o559292 intact-crc:26AB3D14B205800E|rigid:Hz3lN9+lbJc7Nrj6KunRgryHPjc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6Q5K6 uniprotkb:P11986 intact:EBI-392766|ensemblfungi:YML058W-A|uniprotkb:D6VZB5 intact:EBI-9257|ensemblfungi:YJL153C|uniprotkb:D6VW34 psi-mi:hug1_yeast(display_long)|uniprotkb:HUG1(gene name)|psi-mi:HUG1(display_short)|uniprotkb:YML058W-A(locus name) psi-mi:ino1_yeast(display_long)|uniprotkb:INO1(gene name)|psi-mi:INO1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym)|uniprotkb:J0610(orf name)|uniprotkb:YJL153C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316605|imex:IM-14275-246 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML058W-A(gene)|ensemblfungi:YML058W-A_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:1905117"(regulation of ribonucleoside-diphosphate reductase activity)|go:"GO:1990846"(ribonucleoside-diphosphate reductase inhibitor activity)|sgd:S000007472|refseq:NP_219498.1|mint:Q6Q5K6 rcsb pdb:1P1K|ensemblfungi:YJL153C(gene)|ensemblfungi:YJL153C_mRNA(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|rcsb pdb:1JKF|rcsb pdb:1JKI|rcsb pdb:1LA2|rcsb pdb:1P1F|rcsb pdb:1P1H|rcsb pdb:1P1I|rcsb pdb:1P1J|rcsb pdb:1RM0|reactome:R-SCE-1855183|refseq:NP_012382.2|sgd:S000003689|dip:DIP-5687N|mint:P11986 psi-mi:"MI:0469"(intact) - crc64:282E2AE5D156289D figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:x+quBrnP+8yql7JGQ1NK4j5ubbw559292 rogid:3OB3q28fOVxXSBMwMpLe2c1g8p8559292 intact-crc:0DE1F3AF75A76E60|rigid:CaafvVGWw3ZAi/wnYOlBfw2VJ2Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54783 uniprotkb:P11986 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 intact:EBI-9257|ensemblfungi:YJL153C|uniprotkb:D6VW34 psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:ino1_yeast(display_long)|uniprotkb:INO1(gene name)|psi-mi:INO1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym)|uniprotkb:J0610(orf name)|uniprotkb:YJL153C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316594|imex:IM-14275-245 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 rcsb pdb:1P1K|ensemblfungi:YJL153C(gene)|ensemblfungi:YJL153C_mRNA(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|rcsb pdb:1JKF|rcsb pdb:1JKI|rcsb pdb:1LA2|rcsb pdb:1P1F|rcsb pdb:1P1H|rcsb pdb:1P1I|rcsb pdb:1P1J|rcsb pdb:1RM0|reactome:R-SCE-1855183|refseq:NP_012382.2|sgd:S000003689|dip:DIP-5687N|mint:P11986 psi-mi:"MI:0469"(intact) - crc64:282E2AE5D156289D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 rogid:3OB3q28fOVxXSBMwMpLe2c1g8p8559292 intact-crc:5CDDAD56FEF8DFB3|rigid:6Srt7sBYahQvM3nEJVVPLBKxU1M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47039 uniprotkb:P11986 intact:EBI-25893|uniprotkb:D6VWC2|ensemblfungi:YJL060W intact:EBI-9257|ensemblfungi:YJL153C|uniprotkb:D6VW34 psi-mi:bna3_yeast(display_long)|uniprotkb:YJL060W(locus name)|uniprotkb:J1138(orf name)|uniprotkb:Biosynthesis of nicotinic acid protein 3(gene name synonym)|uniprotkb:BNA3(gene name)|psi-mi:BNA3(display_short)|uniprotkb:Kynurenine aminotransferase(gene name synonym) psi-mi:ino1_yeast(display_long)|uniprotkb:INO1(gene name)|psi-mi:INO1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym)|uniprotkb:J0610(orf name)|uniprotkb:YJL153C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316583|imex:IM-14275-244 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003596|refseq:NP_012475.3|mint:P47039|dip:DIP-6723N|ensemblfungi:YJL060W(gene)|ensemblfungi:YJL060W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0016212"(kynurenine-oxoglutarate transaminase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034276"(kynurenic acid biosynthetic process)|go:"GO:0047536"(2-aminoadipate transaminase activity)|go:"GO:0097053"(L-kynurenine catabolic process)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:3B46|reactome:R-SCE-71240|reactome:R-SCE-8964208|reactome:R-SCE-8964539 rcsb pdb:1P1K|ensemblfungi:YJL153C(gene)|ensemblfungi:YJL153C_mRNA(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|rcsb pdb:1JKF|rcsb pdb:1JKI|rcsb pdb:1LA2|rcsb pdb:1P1F|rcsb pdb:1P1H|rcsb pdb:1P1I|rcsb pdb:1P1J|rcsb pdb:1RM0|reactome:R-SCE-1855183|refseq:NP_012382.2|sgd:S000003689|dip:DIP-5687N|mint:P11986 psi-mi:"MI:0469"(intact) - crc64:282E2AE5D156289D figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Fli6ip0tteNbMkQG9h7/IBow3ms559292 rogid:3OB3q28fOVxXSBMwMpLe2c1g8p8559292 intact-crc:AAE157E16515B728|rigid:rD6EitOH3yR9NaXTY1iYsbTowiQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P12688 uniprotkb:P40016 intact:EBI-29473|uniprotkb:D6VX69|ensemblfungi:YKL126W intact:EBI-15927|uniprotkb:D3DLS0|ensemblfungi:YER021W psi-mi:ypk1_yeast(display_long)|uniprotkb:YPK1(gene name)|psi-mi:YPK1(display_short)|uniprotkb:Yeast protein kinase 1(gene name synonym)|uniprotkb:Sphingosine-like immunosuppressant resistant protein 2(gene name synonym)|uniprotkb:YKL126W(locus name)|uniprotkb:SLI2(gene name synonym) psi-mi:rpn3_yeast(display_long)|uniprotkb:RPN3(gene name)|psi-mi:RPN3(display_short)|uniprotkb:SUN2(gene name synonym)|uniprotkb:YER021W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316660|imex:IM-14275-251 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012796.1|sgd:S000001609|dip:DIP-4869N|mint:P12688|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006650"(glycerophospholipid metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071311"(cellular response to acetate)|go:"GO:0071555"(cell wall organization)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|reactome:R-SCE-1257604|reactome:R-SCE-1474151|reactome:R-SCE-165158|reactome:R-SCE-198693|reactome:R-SCE-199418|reactome:R-SCE-203615|reactome:R-SCE-389357|reactome:R-SCE-389513|reactome:R-SCE-392451|reactome:R-SCE-450385|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-6804758|reactome:R-SCE-6811558|reactome:R-SCE-9009391|reactome:R-SCE-9031628|ensemblfungi:YKL126W(gene)|ensemblfungi:YKL126W_mRNA(transcript) refseq:NP_010938.1|sgd:S000000823|ensemblfungi:YER021W(gene)|ensemblfungi:YER021W_mRNA(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042176"(regulation of protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|dip:DIP-1322N|mint:P40016 psi-mi:"MI:0469"(intact) crc64:00112BBB849CD2B5 crc64:B08B58663DDA85DC figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CC3QWo+oXFtlqmhdAv9sQNDSXLc559292 rogid:pXkyoZKr0rI5usi19R+TvS4hSso559292 intact-crc:7275F3F7B553839F|rigid:G+OGvy2ylgzmbHZsaY2yBDCYwlw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03010 uniprotkb:P12684 intact:EBI-20070|uniprotkb:P87330|uniprotkb:D6W3M9|ensemblfungi:YPL139C intact:EBI-8384|uniprotkb:E9P8X3|uniprotkb:D6VZ84|ensemblfungi:YLR450W psi-mi:ume1_yeast(display_long)|uniprotkb:UME1(gene name)|psi-mi:UME1(display_short)|uniprotkb:WTM3(gene name synonym)|uniprotkb:YPL139C(locus name)|uniprotkb:LPI7C(orf name)|uniprotkb:WD repeat-containing transcriptional modulator 3(gene name synonym) psi-mi:hmdh2_yeast(display_long)|uniprotkb:L9324.2(orf name)|uniprotkb:YLR450W(locus name)|uniprotkb:HMG2(gene name)|psi-mi:HMG2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316649|imex:IM-14275-250 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015186.1|sgd:S000006060|ensemblfungi:YPL139C(gene)|ensemblfungi:YPL139C_mRNA(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070210"(Rpd3L-Expanded complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR036322|reactome:R-SCE-3214815|reactome:R-SCE-3214847|reactome:R-SCE-3214858|dip:DIP-5290N|mint:Q03010 refseq:NP_013555.1|sgd:S000004442|mint:P12684|dip:DIP-6277N|ensemblfungi:YLR450W(gene)|ensemblfungi:YLR450W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005635"(nuclear envelope)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0034399"(nuclear periphery)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|interpro:IPR025583 psi-mi:"MI:0469"(intact) crc64:AA6F60448B7BCBA9 crc64:1FD9DCD3AC01B15E figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:radf8gBaPrKRK281JuKAYZprO34559292 rogid:6q1hM5csy4DSYUsSGyTr8M6b9r0559292 intact-crc:BB08880E93E61A80|rigid:yyE7EwtqPtOg+ynLbPw2rjKNBA0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P12684 uniprotkb:P38837 intact:EBI-8384|uniprotkb:E9P8X3|uniprotkb:D6VZ84|ensemblfungi:YLR450W intact:EBI-24733|uniprotkb:D3DL82|uniprotkb:Q6Q5G1|ensemblfungi:YHR133C psi-mi:hmdh2_yeast(display_long)|uniprotkb:L9324.2(orf name)|uniprotkb:YLR450W(locus name)|uniprotkb:HMG2(gene name)|psi-mi:HMG2(display_short) psi-mi:nsg1_yeast(display_long)|uniprotkb:INSIG homolog 1(gene name synonym)|uniprotkb:YHR133C(locus name)|uniprotkb:NSG1(gene name)|psi-mi:NSG1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316638|imex:IM-14275-249 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013555.1|sgd:S000004442|mint:P12684|dip:DIP-6277N|ensemblfungi:YLR450W(gene)|ensemblfungi:YLR450W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005635"(nuclear envelope)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0034399"(nuclear periphery)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|interpro:IPR025583 sgd:S000001175|refseq:NP_012001.1|dip:DIP-2775N|mint:P38837|ensemblfungi:YHR133C(gene)|ensemblfungi:YHR133C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR025929 psi-mi:"MI:0469"(intact) crc64:1FD9DCD3AC01B15E - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6q1hM5csy4DSYUsSGyTr8M6b9r0559292 rogid:ALle5Ub0gjK3Uh+6sfIgbfa7BYw559292 intact-crc:E18AB3A3CD81B910|rigid:GodNPZqxiM9FrcBpePDdlt2orgQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P12684 uniprotkb:P12684 intact:EBI-8384|uniprotkb:E9P8X3|uniprotkb:D6VZ84|ensemblfungi:YLR450W intact:EBI-8384|uniprotkb:E9P8X3|uniprotkb:D6VZ84|ensemblfungi:YLR450W psi-mi:hmdh2_yeast(display_long)|uniprotkb:L9324.2(orf name)|uniprotkb:YLR450W(locus name)|uniprotkb:HMG2(gene name)|psi-mi:HMG2(display_short) psi-mi:hmdh2_yeast(display_long)|uniprotkb:L9324.2(orf name)|uniprotkb:YLR450W(locus name)|uniprotkb:HMG2(gene name)|psi-mi:HMG2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316627|imex:IM-14275-248 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013555.1|sgd:S000004442|mint:P12684|dip:DIP-6277N|ensemblfungi:YLR450W(gene)|ensemblfungi:YLR450W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005635"(nuclear envelope)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0034399"(nuclear periphery)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|interpro:IPR025583 refseq:NP_013555.1|sgd:S000004442|mint:P12684|dip:DIP-6277N|ensemblfungi:YLR450W(gene)|ensemblfungi:YLR450W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005635"(nuclear envelope)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0034399"(nuclear periphery)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|interpro:IPR025583 psi-mi:"MI:0469"(intact) crc64:1FD9DCD3AC01B15E crc64:1FD9DCD3AC01B15E figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6q1hM5csy4DSYUsSGyTr8M6b9r0559292 rogid:6q1hM5csy4DSYUsSGyTr8M6b9r0559292 intact-crc:A06AC7339E047D4E|rigid:R6gc+9h0Iyurm8xBDMMU9B1oGHU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P12962 uniprotkb:P43592 intact:EBI-9010|ensemblfungi:YOR276W|uniprotkb:D6W2X6 intact:EBI-22932|uniprotkb:D6VTN8|ensemblfungi:YFR008W psi-mi:caf20_yeast(display_long)|uniprotkb:CAF20(gene name)|psi-mi:CAF20(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:YOR276W(locus name)|uniprotkb:O5453W(orf name)|uniprotkb:CAF2(gene name synonym)|uniprotkb:20 kDa cap-associated protein(gene name synonym)|uniprotkb:CCR4-associated factor 2(gene name synonym)|uniprotkb:p20(gene name synonym) psi-mi:far7_yeast(display_long)|uniprotkb:YFR008W(locus name)|uniprotkb:FAR7(gene name)|psi-mi:FAR7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316693|imex:IM-14275-254 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|ensemblfungi:YOR276W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR031456|rcsb pdb:6FC3|ensemblfungi:YOR276W_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|refseq:NP_014919.3|sgd:S000005802|mint:P12962|dip:DIP-1222N sgd:S000001904|refseq:NP_116663.1|dip:DIP-1315N|mint:P43592|ensemblfungi:YFR008W(gene)|ensemblfungi:YFR008W_mRNA(transcript)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol) psi-mi:"MI:0469"(intact) crc64:870CA17343798805 crc64:81156978FF7AAD54 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kASAaK/Su6U+5B2V3DjnUSn+k7Y559292 rogid:RB7IaPAzOtEtryalHHz8psxOYqw559292 intact-crc:D9079877506F72D2|rigid:N+d5toQWJ9of0lmMNv2bFvdnwrk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38009 uniprotkb:P12962 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 intact:EBI-9010|ensemblfungi:YOR276W|uniprotkb:D6W2X6 psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:caf20_yeast(display_long)|uniprotkb:CAF20(gene name)|psi-mi:CAF20(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:YOR276W(locus name)|uniprotkb:O5453W(orf name)|uniprotkb:CAF2(gene name synonym)|uniprotkb:20 kDa cap-associated protein(gene name synonym)|uniprotkb:CCR4-associated factor 2(gene name synonym)|uniprotkb:p20(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316682|imex:IM-14275-253 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|ensemblfungi:YOR276W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR031456|rcsb pdb:6FC3|ensemblfungi:YOR276W_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|refseq:NP_014919.3|sgd:S000005802|mint:P12962|dip:DIP-1222N psi-mi:"MI:0469"(intact) crc64:8ABA71761B512242 crc64:870CA17343798805 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 rogid:kASAaK/Su6U+5B2V3DjnUSn+k7Y559292 intact-crc:E507C988BC0EECB2|rigid:ekn9rfibUpUYD4Lv+L9jJcZAIQs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TGU5 uniprotkb:P12954 intact:EBI-2042814|uniprotkb:D6VQU1|ensemblfungi:YBR296C-A intact:EBI-18110|uniprotkb:D6VW92|ensemblfungi:YJL092W psi-mi:yb296_yeast(display_long)|uniprotkb:YBR296C-A(locus name) psi-mi:srs2_yeast(display_long)|uniprotkb:SRS2(gene name)|psi-mi:SRS2(display_short)|uniprotkb:HPR5(gene name synonym)|uniprotkb:RADH(gene name synonym)|uniprotkb:YJL092W(locus name)|uniprotkb:J0913(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316671|imex:IM-14275-252 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000028605|refseq:NP_878055.3|mint:Q8TGU5|ensemblfungi:YBR296C-A(gene)|ensemblfungi:YBR296C-A_mRNA(transcript)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity) refseq:NP_012443.1|sgd:S000003628|ensemblfungi:YJL092W(gene)|ensemblfungi:YJL092W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0042262"(DNA protection)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990986"(DNA recombinase disassembly)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR000212(DNA helicase, UvrD/REP type)|interpro:IPR013986(DNA helicase, DEXX box type)|interpro:IPR014016(Helicase, superfamily 1, UvrD-related)|interpro:IPR014017(DNA helicase, UvrD-like, C terminal)|interpro:IPR027417|rcsb pdb:3V62|go:"GO:0045910"(negative regulation of DNA recombination)|dip:DIP-415N|mint:P12954 psi-mi:"MI:0469"(intact) - crc64:AE8061B114C32120 figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:DZubWD7lnwtea4Ne/bK1ITPFaJk559292 rogid:GPTnvVDJ0ykp+hUzpxAC8L85UsE559292 intact-crc:BDBF0092D82988DA|rigid:8usfjelnsv/iK/+N33GEL1b12Ms false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23202 uniprotkb:P13045 intact:EBI-20138|uniprotkb:D6W0W3|ensemblfungi:YNL229C intact:EBI-7282|uniprotkb:D6VRZ6|ensemblfungi:YDR009W psi-mi:ure2_yeast(display_long)|uniprotkb:URE2(gene name)|psi-mi:URE2(display_short)|uniprotkb:Disulfide reductase(gene name synonym)|uniprotkb:Glutathione peroxidase(gene name synonym)|uniprotkb:N1165(orf name)|uniprotkb:YNL229C(locus name) psi-mi:gal3_yeast(display_long)|uniprotkb:YD8119.14(orf name)|uniprotkb:YDR009W(locus name)|uniprotkb:GAL3(gene name)|psi-mi:GAL3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316726|imex:IM-14275-257 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014170.1|sgd:S000005173|ensemblfungi:YNL229C(gene)|ensemblfungi:YNL229C_mRNA(transcript)|mint:P23202|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0010044"(response to aluminum ion)|go:"GO:0032447"(protein urmylation)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR017298(Prion URE2)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:1G6W|rcsb pdb:1G6Y|rcsb pdb:1HQO|rcsb pdb:1JZR|rcsb pdb:1K0A|rcsb pdb:1K0B|rcsb pdb:1K0C|rcsb pdb:1K0D|go:"GO:0003714"(transcription corepressor activity)|dip:DIP-1308N refseq:NP_010292.1|sgd:S000002416|mint:P13045|dip:DIP-5725N|ensemblfungi:YDR009W(gene)|ensemblfungi:YDR009W_mRNA(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0045185"(maintenance of protein location)|interpro:IPR000705(Galactokinase)|interpro:IPR006204(GHMP kinase)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR019539|interpro:IPR019741|interpro:IPR020568|interpro:IPR036554|rcsb pdb:3V2U|rcsb pdb:3V5R psi-mi:"MI:0469"(intact) crc64:2C628976034B0F1C crc64:5852028EBDDC0F3B figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jjsWygBsEp8axNurMa3pxPMQJ2k559292 rogid:EtOtuZODEOlw/PgA2I0MimDXYsU559292 intact-crc:C7D916838D868F91|rigid:Ud1twEYit7UCCtqN8wOZsfRRnTU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P12962 uniprotkb:Q08446 intact:EBI-9010|ensemblfungi:YOR276W|uniprotkb:D6W2X6 intact:EBI-17070|ensemblfungi:YOR057W|uniprotkb:D6W2C0|uniprotkb:E9P8U7 psi-mi:caf20_yeast(display_long)|uniprotkb:CAF20(gene name)|psi-mi:CAF20(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:YOR276W(locus name)|uniprotkb:O5453W(orf name)|uniprotkb:CAF2(gene name synonym)|uniprotkb:20 kDa cap-associated protein(gene name synonym)|uniprotkb:CCR4-associated factor 2(gene name synonym)|uniprotkb:p20(gene name synonym) psi-mi:sgt1_yeast(display_long)|uniprotkb:SGT1(gene name)|psi-mi:SGT1(display_short)|uniprotkb:YOR057W(locus name)|uniprotkb:YOR29-08(orf name)|uniprotkb:Suppressor of G2 allele of SKP1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316715|imex:IM-14275-256 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|ensemblfungi:YOR276W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR031456|rcsb pdb:6FC3|ensemblfungi:YOR276W_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|refseq:NP_014919.3|sgd:S000005802|mint:P12962|dip:DIP-1222N refseq:NP_014700.1|sgd:S000005583|ensemblfungi:YOR057W(gene)|ensemblfungi:YOR057W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0007049"(cell cycle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034622"|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044563|rcsb pdb:5AN3|reactome:R-SCE-844456|dip:DIP-1628N|mint:Q08446 psi-mi:"MI:0469"(intact) crc64:870CA17343798805 crc64:5DE65874BE155552 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kASAaK/Su6U+5B2V3DjnUSn+k7Y559292 rogid:DJ37U8QHPE7Wi/+kOiEwCg1mxCw559292 intact-crc:EF7A15CF6FFA6772|rigid:mQLz5DkIBNhWPbW2z8UsGDTNgrY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P12962 uniprotkb:P53235 intact:EBI-9010|ensemblfungi:YOR276W|uniprotkb:D6W2X6 intact:EBI-23172|uniprotkb:D6VUI9|uniprotkb:Q45U32|ensemblfungi:YGR054W psi-mi:caf20_yeast(display_long)|uniprotkb:CAF20(gene name)|psi-mi:CAF20(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:YOR276W(locus name)|uniprotkb:O5453W(orf name)|uniprotkb:CAF2(gene name synonym)|uniprotkb:20 kDa cap-associated protein(gene name synonym)|uniprotkb:CCR4-associated factor 2(gene name synonym)|uniprotkb:p20(gene name synonym) psi-mi:eif2a_yeast(display_long)|uniprotkb:YGR054W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316704|imex:IM-14275-255 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|ensemblfungi:YOR276W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR031456|rcsb pdb:6FC3|ensemblfungi:YOR276W_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|refseq:NP_014919.3|sgd:S000005802|mint:P12962|dip:DIP-1222N sgd:S000003286|refseq:NP_011568.3|dip:DIP-5518N|mint:P53235|ensemblfungi:YGR054W(gene)|ensemblfungi:YGR054W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like) psi-mi:"MI:0469"(intact) crc64:870CA17343798805 crc64:F3C2E78504D83418 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kASAaK/Su6U+5B2V3DjnUSn+k7Y559292 rogid:x8zDCH5W5GusC7qYd0mDATXhGVI559292 intact-crc:923332B4BA8D51D9|rigid:5x202lfk+j09gPyrk9KADr9sm30 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13134 uniprotkb:P29465 intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5 intact:EBI-4632|uniprotkb:D6VQ25|ensemblfungi:YBR023C psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym) psi-mi:chs3_yeast(display_long)|uniprotkb:CHS3(gene name)|psi-mi:CHS3(display_short)|uniprotkb:CAL1(gene name synonym)|uniprotkb:DIT101(gene name synonym)|uniprotkb:KIT2(gene name synonym)|uniprotkb:YBR023C(locus name)|uniprotkb:CSD2(gene name synonym)|uniprotkb:YBR0305(orf name)|uniprotkb:Chitin-UDP acetyl-glucosaminyl transferase 3(gene name synonym)|uniprotkb:Class-IV chitin synthase 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316759|imex:IM-14275-260 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134 refseq:NP_009579.1|sgd:S000000227|dip:DIP-2482N|mint:P29465|ensemblfungi:YBR023C(gene)|ensemblfungi:YBR023C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0004100"(chitin synthase activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030428"(cell septum)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0045009"(chitosome)|go:"GO:0071944"(cell periphery)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR004835(Fungal chitin synthase)|interpro:IPR029044|rcsb pdb:4WJW psi-mi:"MI:0469"(intact) crc64:5DCEEDADCF439C78 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292 rogid:8Ik0u35UXSJVtqfgNdo49J+nzFk559292 intact-crc:4C9F5D8B83F3C555|rigid:waFKBong/vcDI3jXyqycBLOZ7/I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11075 uniprotkb:P13134 intact:EBI-16882|uniprotkb:Q03960|uniprotkb:Q04139|uniprotkb:D6VSF1|ensemblfungi:YDR170C intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5 psi-mi:sec7_yeast(display_long)|uniprotkb:SEC7(gene name)|psi-mi:SEC7(display_short)|uniprotkb:YD9395.01C(orf name)|uniprotkb:YD9489.05C(orf name)|uniprotkb:YDR170C(locus name) psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316748|imex:IM-14275-259 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010454.3|ensemblfungi:YDR170C(gene)|ensemblfungi:YDR170C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005770"(late endosome)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0032012"(regulation of ARF protein signal transduction)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|rcsb pdb:4OIY|go:"GO:0015031"(protein transport)|sgd:S000002577|dip:DIP-830N|mint:P11075 interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134 psi-mi:"MI:0469"(intact) crc64:02B2D370DD2E4661 crc64:5DCEEDADCF439C78 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BoKfHXfAHnYKyYGbglgZr/3djRw559292 rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292 intact-crc:0DF08698D46A92A3|rigid:s0Da4apWxvi4xDxyn3sr7gtXLh8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:P13134 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5 psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316737|imex:IM-14275-258 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134 psi-mi:"MI:0469"(intact) - crc64:5DCEEDADCF439C78 figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292 intact-crc:5C307609EBA65EEA|rigid:zpFwRxBiJoUGwWihoIcTv+g+VZA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39005 uniprotkb:P13259 intact:EBI-9930|uniprotkb:D6VW14|ensemblfungi:YJL174W intact:EBI-5254|uniprotkb:D6VUY4|ensemblfungi:YGR202C psi-mi:kre9_yeast(display_long)|uniprotkb:KRE9(gene name)|psi-mi:KRE9(display_short)|uniprotkb:J0504(orf name)|uniprotkb:YJL174W(locus name) psi-mi:pcy1_yeast(display_long)|uniprotkb:PCT1(gene name)|psi-mi:PCT1(display_short)|uniprotkb:CCT(gene name synonym)|uniprotkb:CCT1(gene name synonym)|uniprotkb:YGR202C(locus name)|uniprotkb:G7729(orf name)|uniprotkb:Phosphorylcholine transferase(gene name synonym)|uniprotkb:"CTP:phosphocholine cytidylyltransferase"(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316781|imex:IM-14275-262 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012361.1|sgd:S000003710|ensemblfungi:YJL174W(gene)|ensemblfungi:YJL174W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0006077"("(1->6)-beta-D-glucan metabolic process")|go:"GO:0006078"("(1->6)-beta-D-glucan biosynthetic process")|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0042546"(cell wall biogenesis)|interpro:IPR008659(Yeast cell wall synthesis KRE9KNH1)|interpro:IPR018466|dip:DIP-5609N|mint:P39005 refseq:NP_011718.1|sgd:S000003434|dip:DIP-6390N|mint:P13259|ensemblfungi:YGR202C(gene)|ensemblfungi:YGR202C_mRNA(transcript)|go:"GO:0004105"(choline-phosphate cytidylyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0006657"(CDP-choline pathway)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR041723|reactome:R-SCE-1483191 psi-mi:"MI:0469"(intact) - crc64:246774FE2F7124A3 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jBKI+ZR5HsosCLJPinn8LNFqIcU559292 rogid:axfmmLeeYGCWRp4eBXlohHWafOo559292 intact-crc:9A821BE79CDF89E6|rigid:e/QG0KTz7oh1cWzarmPcDbVdEO0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13134 uniprotkb:Q08967 intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5 intact:EBI-36673|uniprotkb:D6W3E9|ensemblfungi:YPL221W psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym) psi-mi:flc1_yeast(display_long)|uniprotkb:FAD transporter 1(gene name synonym)|uniprotkb:FLC1(gene name)|psi-mi:FLC1(display_short)|uniprotkb:TRP-like ion channel protein FLC1(gene name synonym)|uniprotkb:Heme utilization factor 1(gene name synonym)|uniprotkb:Bypass of PAM1 protein 1(gene name synonym)|uniprotkb:HUF1(gene name synonym)|uniprotkb:YPL221W(locus name)|uniprotkb:BOP1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316770|imex:IM-14275-261 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134 refseq:NP_015103.1|sgd:S000006142|mint:Q08967|dip:DIP-3965N|ensemblfungi:YPL221W(gene)|ensemblfungi:YPL221W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055085"(transmembrane transport)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241 psi-mi:"MI:0469"(intact) crc64:5DCEEDADCF439C78 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292 rogid:r6CcZGEjxHUk2w0iBUBvnAPaFd4559292 intact-crc:A4825710E1B26D19|rigid:aMBPk9418Oiui2ISYAXhC0vkJls false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38890 uniprotkb:P13433 intact:EBI-24263|uniprotkb:D3DLF6|ensemblfungi:YHR207C intact:EBI-15960|ensemblfungi:YFL036W|uniprotkb:D6VTJ4 psi-mi:set5_yeast(display_long)|uniprotkb:SET domain-containing protein 5(gene name synonym)|uniprotkb:SET5(gene name)|psi-mi:SET5(display_short)|uniprotkb:YHR207C(locus name) psi-mi:rpom_yeast(display_long)|uniprotkb:RPO41(gene name)|psi-mi:RPO41(display_short)|uniprotkb:YFL036W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316803|imex:IM-14275-264 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012077.1|sgd:S000001250|dip:DIP-2725N|mint:P38890|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034968"(histone lysine methylation)|interpro:IPR001214(SET)|reactome:R-SCE-3214841|ensemblfungi:YHR207C(gene)|ensemblfungi:YHR207C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000785"(chromatin) ensemblfungi:YFL036W(gene)|ensemblfungi:YFL036W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0034245"(mitochondrial DNA-directed RNA polymerase complex)|go:"GO:0042645"(mitochondrial nucleoid)|interpro:IPR002092(DNA-directed RNA polymerase, bacteriophage type)|interpro:IPR024075|interpro:IPR029262|interpro:IPR037159|interpro:IPR043502|rcsb pdb:6YMV|rcsb pdb:6YMW|refseq:NP_116617.1|sgd:S000001858|dip:DIP-2431N|mint:P13433 psi-mi:"MI:0469"(intact) crc64:1113CB9C5223DC7D - figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:egI+LybV3u2ZIgq8YBIBF42MqkM559292 rogid:RkNeurCN/QEb1A9XMPoZwKTaLqs559292 intact-crc:9A6B69505B41991A|rigid:bHJ3XT3oVtEGPdE+Zsjl5/zNBiU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:P13298 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-14392|uniprotkb:D6W0H8|ensemblfungi:YML106W psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:pyre_yeast(display_long)|uniprotkb:URA5(gene name)|psi-mi:URA5(display_short)|uniprotkb:PYR5(gene name synonym)|uniprotkb:YML106W(locus name)|uniprotkb:YM8339.13(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316792|imex:IM-14275-263 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N ensemblfungi:YML106W_mRNA(transcript)|go:"GO:0004588"(orotate phosphoribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006221"(pyrimidine nucleotide biosynthetic process)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046132"(pyrimidine ribonucleoside biosynthetic process)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR004467(Orotate phosphoribosyl transferase)|interpro:IPR023031|interpro:IPR029057|rcsb pdb:2PRY|rcsb pdb:2PRZ|rcsb pdb:2PS1|rcsb pdb:4WML|rcsb pdb:4WN3|ensemblfungi:YML106W(gene)|refseq:NP_013601.1|sgd:S000004574|mint:P13298|dip:DIP-4859N psi-mi:"MI:0469"(intact) crc64:8B7F009521F72C15 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:yIRvpNYic52x1wotM/ER/56VRS8559292 intact-crc:0AF103D3C90BAB4E|rigid:dSo0AJgC/2J8vbifMJpdZY+wmaI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17555 uniprotkb:P13517 intact:EBI-4024|uniprotkb:D6W144|ensemblfungi:YNL138W intact:EBI-4013|uniprotkb:Q07082|uniprotkb:D6VVP8|ensemblfungi:YIL034C psi-mi:cap_yeast(display_long)|uniprotkb:SRV2(gene name)|psi-mi:SRV2(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:YNL138W(locus name)|uniprotkb:N1210(orf name)|uniprotkb:N1838(orf name) psi-mi:capzb_yeast(display_long)|uniprotkb:YIL034C(locus name)|uniprotkb:CAP2(gene name)|psi-mi:CAP2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316836|imex:IM-14275-267 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014261.1|sgd:S000005082|dip:DIP-77N|ensemblfungi:YNL138W(gene)|ensemblfungi:YNL138W_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007265"(Ras protein signal transduction)|mint:P17555|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0051014"(actin filament severing)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|rcsb pdb:1K4Z|rcsb pdb:1KQ5|reactome:R-SCE-6798695 sgd:S000001296|refseq:NP_012230.3|dip:DIP-836N|ensemblfungi:YIL034C(gene)|ensemblfungi:YIL034C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030447"(filamentous growth)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|reactome:R-SCE-9013405|reactome:R-SCE-983231|mint:P13517 psi-mi:"MI:0469"(intact) crc64:0EB4D41205E2D464 crc64:6E669023D1378778 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3Fs9g+L5RnbkqYThVpOvSFrZoJ8559292 rogid:Kk8QoRXeJ3IU4tLcyHI5y7hDipk559292 intact-crc:B818E1ED92F1AACA|rigid:vuBQMEQHiO8Y7FeB/KE+1mA/mTM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13517 uniprotkb:P13517 intact:EBI-4013|uniprotkb:Q07082|uniprotkb:D6VVP8|ensemblfungi:YIL034C intact:EBI-4013|uniprotkb:Q07082|uniprotkb:D6VVP8|ensemblfungi:YIL034C psi-mi:capzb_yeast(display_long)|uniprotkb:YIL034C(locus name)|uniprotkb:CAP2(gene name)|psi-mi:CAP2(display_short) psi-mi:capzb_yeast(display_long)|uniprotkb:YIL034C(locus name)|uniprotkb:CAP2(gene name)|psi-mi:CAP2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316825|imex:IM-14275-266 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001296|refseq:NP_012230.3|dip:DIP-836N|ensemblfungi:YIL034C(gene)|ensemblfungi:YIL034C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030447"(filamentous growth)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|reactome:R-SCE-9013405|reactome:R-SCE-983231|mint:P13517 sgd:S000001296|refseq:NP_012230.3|dip:DIP-836N|ensemblfungi:YIL034C(gene)|ensemblfungi:YIL034C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030447"(filamentous growth)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|reactome:R-SCE-9013405|reactome:R-SCE-983231|mint:P13517 psi-mi:"MI:0469"(intact) crc64:6E669023D1378778 crc64:6E669023D1378778 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Kk8QoRXeJ3IU4tLcyHI5y7hDipk559292 rogid:Kk8QoRXeJ3IU4tLcyHI5y7hDipk559292 intact-crc:ECE956F3A5A25F8D|rigid:+GKwf0hzaZjXng8DttTXqPlISOU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13433 uniprotkb:P40209 intact:EBI-15960|ensemblfungi:YFL036W|uniprotkb:D6VTJ4 intact:EBI-7347|uniprotkb:D6VZV9|ensemblfungi:YMR136W psi-mi:rpom_yeast(display_long)|uniprotkb:RPO41(gene name)|psi-mi:RPO41(display_short)|uniprotkb:YFL036W(locus name) psi-mi:gat2_yeast(display_long)|uniprotkb:YM9375.05(orf name)|uniprotkb:YMR136W(locus name)|uniprotkb:GAT2(gene name)|psi-mi:GAT2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316814|imex:IM-14275-265 author score:97.90 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YFL036W(gene)|ensemblfungi:YFL036W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0034245"(mitochondrial DNA-directed RNA polymerase complex)|go:"GO:0042645"(mitochondrial nucleoid)|interpro:IPR002092(DNA-directed RNA polymerase, bacteriophage type)|interpro:IPR024075|interpro:IPR029262|interpro:IPR037159|interpro:IPR043502|rcsb pdb:6YMV|rcsb pdb:6YMW|refseq:NP_116617.1|sgd:S000001858|dip:DIP-2431N|mint:P13433 refseq:NP_013856.1|sgd:S000004744|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|mint:P40209|ensemblfungi:YMR136W(gene)|ensemblfungi:YMR136W_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.90|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RkNeurCN/QEb1A9XMPoZwKTaLqs559292 rogid:D9KVdLMpjrjceIWe9QfYq2EoDhI559292 intact-crc:6FE3CEE45F1607D2|rigid:0mzMAifGuSe9YkO3eN5sApiIYhg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13517 uniprotkb:P40518 intact:EBI-4013|uniprotkb:Q07082|uniprotkb:D6VVP8|ensemblfungi:YIL034C intact:EBI-2750|uniprotkb:D6VVM2|ensemblfungi:YIL062C psi-mi:capzb_yeast(display_long)|uniprotkb:YIL034C(locus name)|uniprotkb:CAP2(gene name)|psi-mi:CAP2(display_short) psi-mi:arpc5_yeast(display_long)|uniprotkb:ARC15(gene name)|psi-mi:ARC15(display_short)|uniprotkb:Arp2/3 complex 16 kDa subunit(gene name synonym)|uniprotkb:YIL062C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316858|imex:IM-14275-269 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001296|refseq:NP_012230.3|dip:DIP-836N|ensemblfungi:YIL034C(gene)|ensemblfungi:YIL034C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030447"(filamentous growth)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|reactome:R-SCE-9013405|reactome:R-SCE-983231|mint:P13517 refseq:NP_012202.1|sgd:S000001324|dip:DIP-2101N|mint:P40518|ensemblfungi:YIL062C(gene)|ensemblfungi:YIL062C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR036743|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-6798695|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:6E669023D1378778 crc64:10E4DAF0F0801B02 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Kk8QoRXeJ3IU4tLcyHI5y7hDipk559292 rogid:iQ0mLisINMjXPulrRyDmrLcdpzU559292 intact-crc:599E8FC4998D7B54|rigid:+/UmQ8qyn5Pc7OaGAqgD3WFqQlk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13517 uniprotkb:P38328 intact:EBI-4013|uniprotkb:Q07082|uniprotkb:D6VVP8|ensemblfungi:YIL034C intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C psi-mi:capzb_yeast(display_long)|uniprotkb:YIL034C(locus name)|uniprotkb:CAP2(gene name)|psi-mi:CAP2(display_short) psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316847|imex:IM-14275-268 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001296|refseq:NP_012230.3|dip:DIP-836N|ensemblfungi:YIL034C(gene)|ensemblfungi:YIL034C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030447"(filamentous growth)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|reactome:R-SCE-9013405|reactome:R-SCE-983231|mint:P13517 sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:6E669023D1378778 crc64:D75C6BB8EC35EEDF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Kk8QoRXeJ3IU4tLcyHI5y7hDipk559292 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 intact-crc:01ED33049F41BB52|rigid:93XytPGh58/9jAAJzMKmv9fSECE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13517 uniprotkb:P50079 intact:EBI-4013|uniprotkb:Q07082|uniprotkb:D6VVP8|ensemblfungi:YIL034C intact:EBI-23505|uniprotkb:D6VV05|ensemblfungi:YGR223C psi-mi:capzb_yeast(display_long)|uniprotkb:YIL034C(locus name)|uniprotkb:CAP2(gene name)|psi-mi:CAP2(display_short) psi-mi:hsv2_yeast(display_long)|uniprotkb:G8530(orf name)|uniprotkb:YGR223C(locus name)|uniprotkb:HSV2(gene name)|psi-mi:HSV2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316880|imex:IM-14275-271 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001296|refseq:NP_012230.3|dip:DIP-836N|ensemblfungi:YIL034C(gene)|ensemblfungi:YIL034C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030447"(filamentous growth)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|reactome:R-SCE-9013405|reactome:R-SCE-983231|mint:P13517 refseq:NP_011739.1|sgd:S000003455|dip:DIP-5556N|mint:P50079|ensemblfungi:YGR223C(gene)|ensemblfungi:YGR223C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006497"(protein lipidation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-SCE-1632852 psi-mi:"MI:0469"(intact) crc64:6E669023D1378778 crc64:A4287FAB80AA68DF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Kk8QoRXeJ3IU4tLcyHI5y7hDipk559292 rogid:ry4AOefJ9FKdASKObhv/F29TfxQ559292 intact-crc:521D8CD410A2A5C6|rigid:dGhzz6bJPTFxqdZFkSoYCHCqwBQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13517 uniprotkb:P40563 intact:EBI-4013|uniprotkb:Q07082|uniprotkb:D6VVP8|ensemblfungi:YIL034C intact:EBI-25376|uniprotkb:D6VVT3|ensemblfungi:YIR003W psi-mi:capzb_yeast(display_long)|uniprotkb:YIL034C(locus name)|uniprotkb:CAP2(gene name)|psi-mi:CAP2(display_short) psi-mi:aim21_yeast(display_long)|uniprotkb:YIB3W(orf name)|uniprotkb:YIR003W(locus name)|uniprotkb:AIM21(gene name)|psi-mi:AIM21(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316869|imex:IM-14275-270 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001296|refseq:NP_012230.3|dip:DIP-836N|ensemblfungi:YIL034C(gene)|ensemblfungi:YIL034C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030447"(filamentous growth)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|reactome:R-SCE-9013405|reactome:R-SCE-983231|mint:P13517 sgd:S000001442|refseq:NP_012268.3|mint:P40563|dip:DIP-5096N|ensemblfungi:YIR003W(gene)|ensemblfungi:YIR003W_mRNA(transcript)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0034642"(mitochondrion migration along actin filament)|go:"GO:0043332"(mating projection tip)|go:"GO:0110131"(Aim21-Tda2 complex)|interpro:IPR021582 psi-mi:"MI:0469"(intact) crc64:6E669023D1378778 crc64:9DF79500375339E7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Kk8QoRXeJ3IU4tLcyHI5y7hDipk559292 rogid:R3iO4ZZ2CQ4DGVK4ixn30Od6Tho559292 intact-crc:4203E4AE2ACAA695|rigid:tUtoKBU+U5e42YJg6XnUCx9CCEk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06408 uniprotkb:P13517 intact:EBI-32807|uniprotkb:D6VT13|ensemblfungi:YDR380W intact:EBI-4013|uniprotkb:Q07082|uniprotkb:D6VVP8|ensemblfungi:YIL034C psi-mi:aro10_yeast(display_long)|uniprotkb:ARO10(gene name)|psi-mi:ARO10(display_short)|uniprotkb:YDR380W(locus name)|uniprotkb:D9481.3(orf name)|uniprotkb:Transaminated branched-chain amino acid decarboxylase(gene name synonym)|uniprotkb:Thiamine diphosphate-dependent phenylpyruvate decarboxylase(gene name synonym)|uniprotkb:Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase(gene name synonym) psi-mi:capzb_yeast(display_long)|uniprotkb:YIL034C(locus name)|uniprotkb:CAP2(gene name)|psi-mi:CAP2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316902|imex:IM-14275-273 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002788|refseq:NP_010668.3|dip:DIP-5252N|mint:Q06408|ensemblfungi:YDR380W(gene)|ensemblfungi:YDR380W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000949"(aromatic amino acid family catabolic process to alcohol via Ehrlich pathway)|go:"GO:0000950"(branched-chain amino acid catabolic process to alcohol via Ehrlich pathway)|go:"GO:0000951"(methionine catabolic process to 3-methylthiopropanol)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0006559"(L-phenylalanine catabolic process)|go:"GO:0006569"(tryptophan catabolic process)|go:"GO:0006572"(tyrosine catabolic process)|go:"GO:0016831"(carboxy-lyase activity)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0047433"(branched-chain-2-oxoacid decarboxylase activity)|go:"GO:0047434"(indolepyruvate decarboxylase activity)|go:"GO:0050177"(phenylpyruvate decarboxylase activity)|go:"GO:0050546"(4-hydroxyphenylpyruvate decarboxylase activity)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR012110(Pyruvate decarboxylase/indolepyruvate decarboxylase)|interpro:IPR029035|interpro:IPR029061 sgd:S000001296|refseq:NP_012230.3|dip:DIP-836N|ensemblfungi:YIL034C(gene)|ensemblfungi:YIL034C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030447"(filamentous growth)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|reactome:R-SCE-9013405|reactome:R-SCE-983231|mint:P13517 psi-mi:"MI:0469"(intact) crc64:616DF7E06DA82415 crc64:6E669023D1378778 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jh443SvRXK8vb+GUjPq95NB8jdU559292 rogid:Kk8QoRXeJ3IU4tLcyHI5y7hDipk559292 intact-crc:823C9C4D0D0FEBB1|rigid:HH9nPaheBjo9fLeJzdcoD4oh+cE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53731 uniprotkb:P13517 intact:EBI-2770|uniprotkb:D6W1L1|ensemblfungi:YNR035C intact:EBI-4013|uniprotkb:Q07082|uniprotkb:D6VVP8|ensemblfungi:YIL034C psi-mi:arpc2_yeast(display_long)|uniprotkb:ARC35(gene name)|psi-mi:ARC35(display_short)|uniprotkb:YNR035C(locus name)|uniprotkb:N3296(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym) psi-mi:capzb_yeast(display_long)|uniprotkb:YIL034C(locus name)|uniprotkb:CAP2(gene name)|psi-mi:CAP2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316891|imex:IM-14275-272 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014433.1|sgd:S000005318|dip:DIP-2304N|mint:P53731|ensemblfungi:YNR035C(gene)|ensemblfungi:YNR035C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072697"(protein localization to cell cortex)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 sgd:S000001296|refseq:NP_012230.3|dip:DIP-836N|ensemblfungi:YIL034C(gene)|ensemblfungi:YIL034C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030447"(filamentous growth)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|reactome:R-SCE-9013405|reactome:R-SCE-983231|mint:P13517 psi-mi:"MI:0469"(intact) crc64:9AF71A93688729F6 crc64:6E669023D1378778 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:URdgP2srz1O44fNGQh18L7bzC+c559292 rogid:Kk8QoRXeJ3IU4tLcyHI5y7hDipk559292 intact-crc:16DC5C065D7815BB|rigid:owBrOsRlzrzybWa8Ya21XiP4x/Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04177 uniprotkb:P13574 intact:EBI-35844|uniprotkb:D6VT31|ensemblfungi:YDR398W intact:EBI-18264|uniprotkb:D3DL35|ensemblfungi:YHR084W psi-mi:utp5_yeast(display_long)|uniprotkb:U three protein 5(gene name synonym)|uniprotkb:U3 protein 5 required for transcription(gene name synonym)|uniprotkb:D9509.17(orf name)|uniprotkb:YDR398W(locus name)|uniprotkb:UTP5(gene name)|psi-mi:UTP5(display_short)|uniprotkb:t-UTP5(gene name synonym) psi-mi:ste12_yeast(display_long)|uniprotkb:STE12(gene name)|psi-mi:STE12(display_short)|uniprotkb:YHR084W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316924|imex:IM-14275-275 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010686.1|sgd:S000002806|mint:Q04177|dip:DIP-1317N|ensemblfungi:YDR398W(gene)|ensemblfungi:YDR398W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034455"(t-UTP complex)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|rcsb pdb:6LQS refseq:NP_011952.1|sgd:S000001126|go:"GO:0007329"(positive regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:0019953"(sexual reproduction)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:1990526"(Ste12p-Dig1p-Dig2p complex)|go:"GO:1990527"(Tec1p-Ste12p-Dig1p complex)|go:"GO:2000220"(regulation of pseudohyphal growth)|interpro:IPR003120(Transcription factor, STE-like)|rcsb pdb:3W3W|ensemblfungi:YHR084W(gene)|ensemblfungi:YHR084W_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007124"(pseudohyphal growth)|dip:DIP-64N|mint:P13574 psi-mi:"MI:0469"(intact) crc64:7A6F60C7C6F46C2A crc64:EE7371F18BBC0337 figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cpoFrHdK29TtGOfAINI5ceEgO3U559292 rogid:MdXJ5MVLjUEpzwQv3mhihuiFPbQ559292 intact-crc:5A6B8C40A1840CDA|rigid:suE2YSQjAMRbsdt48yLhcFcwxLc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01080 uniprotkb:P13574 intact:EBI-15741|uniprotkb:D6W0U5|ensemblfungi:YNL248C intact:EBI-18264|uniprotkb:D3DL35|ensemblfungi:YHR084W psi-mi:rpa49_yeast(display_long)|uniprotkb:RPA49(gene name)|psi-mi:RPA49(display_short)|uniprotkb:RRN13(gene name synonym)|uniprotkb:YNL248C(locus name)|uniprotkb:N0880(orf name)|uniprotkb:DNA-directed RNA polymerase I 49 kDa polypeptide(gene name synonym) psi-mi:ste12_yeast(display_long)|uniprotkb:STE12(gene name)|psi-mi:STE12(display_short)|uniprotkb:YHR084W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316913|imex:IM-14275-274 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014151.1|sgd:S000005192|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0008361"(regulation of cell size)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR009668(RNA polymerase I associated factor, A49-like)|rcsb pdb:3NFH|rcsb pdb:3NFI|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|ensemblfungi:YNL248C(gene)|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|ensemblfungi:YNL248C_mRNA(transcript)|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|go:"GO:0001054"(RNA polymerase I activity)|rcsb pdb:6H67|rcsb pdb:6H68|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|rcsb pdb:6HKO|rcsb pdb:6RQH|dip:DIP-6577N|mint:Q01080 refseq:NP_011952.1|sgd:S000001126|go:"GO:0007329"(positive regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:0019953"(sexual reproduction)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:1990526"(Ste12p-Dig1p-Dig2p complex)|go:"GO:1990527"(Tec1p-Ste12p-Dig1p complex)|go:"GO:2000220"(regulation of pseudohyphal growth)|interpro:IPR003120(Transcription factor, STE-like)|rcsb pdb:3W3W|ensemblfungi:YHR084W(gene)|ensemblfungi:YHR084W_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007124"(pseudohyphal growth)|dip:DIP-64N|mint:P13574 psi-mi:"MI:0469"(intact) crc64:3D9BF05440D26021 crc64:EE7371F18BBC0337 figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:B7Nabi651A5fAilRf/0F2GHps/U559292 rogid:MdXJ5MVLjUEpzwQv3mhihuiFPbQ559292 intact-crc:A636C0F2C40E635B|rigid:LXsNhgHJFXxGMhGsL0rL6G4wFjQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:P14359 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316957|imex:IM-14275-278 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:053A67CC63C66F11|rigid:ggX7i4hK4bpUnCsmDAzFIm9Jx2U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11986 uniprotkb:P14065 intact:EBI-9257|ensemblfungi:YJL153C|uniprotkb:D6VW34 intact:EBI-7505|uniprotkb:D6W2H9|ensemblfungi:YOR120W psi-mi:ino1_yeast(display_long)|uniprotkb:INO1(gene name)|psi-mi:INO1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym)|uniprotkb:J0610(orf name)|uniprotkb:YJL153C(locus name) psi-mi:gcy1_yeast(display_long)|uniprotkb:GCY1(gene name)|psi-mi:GCY1(display_short)|uniprotkb:GCY(gene name synonym)|uniprotkb:Galactose-inducible crystallin-like protein 1(gene name synonym)|uniprotkb:O31567(orf name)|uniprotkb:YOR3269W(orf name)|uniprotkb:YOR120W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316946|imex:IM-14275-277 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1P1K|ensemblfungi:YJL153C(gene)|ensemblfungi:YJL153C_mRNA(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|rcsb pdb:1JKF|rcsb pdb:1JKI|rcsb pdb:1LA2|rcsb pdb:1P1F|rcsb pdb:1P1H|rcsb pdb:1P1I|rcsb pdb:1P1J|rcsb pdb:1RM0|reactome:R-SCE-1855183|refseq:NP_012382.2|sgd:S000003689|dip:DIP-5687N|mint:P11986 refseq:NP_014763.1|sgd:S000005646|mint:P14065|dip:DIP-6342N|ensemblfungi:YOR120W(gene)|ensemblfungi:YOR120W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004032"("alditol:NADP+ 1-oxidoreductase activity")|go:"GO:0004033"("aldo-keto reductase (NADP) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019568"(arabinose catabolic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042843"(D-xylose catabolic process)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0047953"("glycerol 2-dehydrogenase (NADP+) activity")|go:"GO:0061610"(glycerol to glycerone phosphate metabolic process)|go:"GO:1990042"("glycerol dehydrogenase [NAD(P)+] activity")|interpro:IPR018170|interpro:IPR020471|interpro:IPR023210|interpro:IPR036812|interpro:IPR044489 psi-mi:"MI:0469"(intact) crc64:282E2AE5D156289D crc64:77B9D31C228334A4 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3OB3q28fOVxXSBMwMpLe2c1g8p8559292 rogid:yd837LUbGfDWJfUk9YxH3WRPQ18559292 intact-crc:8ABE5263964960A5|rigid:wahEaP2Vrz+tiLEvvD3JqR1Q+z8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13711 uniprotkb:P40016 intact:EBI-3999|uniprotkb:D6VTV0|ensemblfungi:YGL205W intact:EBI-15927|uniprotkb:D3DLS0|ensemblfungi:YER021W psi-mi:acox_yeast(display_long)|uniprotkb:POX1(gene name)|psi-mi:POX1(display_short)|uniprotkb:FOX1(gene name synonym)|uniprotkb:YGL205W(locus name) psi-mi:rpn3_yeast(display_long)|uniprotkb:RPN3(gene name)|psi-mi:RPN3(display_short)|uniprotkb:SUN2(gene name synonym)|uniprotkb:YER021W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316935|imex:IM-14275-276 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011310.1|sgd:S000003173|dip:DIP-6592N|mint:P13711|ensemblfungi:YGL205W(gene)|ensemblfungi:YGL205W_mRNA(transcript)|go:"GO:0003997"(acyl-CoA oxidase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0033540"(fatty acid beta-oxidation using acyl-CoA oxidase)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0071949"(FAD binding)|interpro:IPR002655(Acyl-CoA oxidase, C-terminal)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR012258(Acyl-CoA oxidase)|interpro:IPR029320|interpro:IPR034171|interpro:IPR036250|reactome:R-SCE-389887 refseq:NP_010938.1|sgd:S000000823|ensemblfungi:YER021W(gene)|ensemblfungi:YER021W_mRNA(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042176"(regulation of protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|dip:DIP-1322N|mint:P40016 psi-mi:"MI:0469"(intact) crc64:5C0664455A050BDA crc64:B08B58663DDA85DC figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Cthk8kmT4q6Y0g4zXnUXN1gzXLc559292 rogid:pXkyoZKr0rI5usi19R+TvS4hSso559292 intact-crc:8C063C07C2B4D553|rigid:IpoC5fchLSZnb69mdBBysKEQZQ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25361 uniprotkb:P14359 intact:EBI-21909|uniprotkb:D6VR52|ensemblfungi:YCR043C intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:yct3_yeast(display_long)|uniprotkb:YCR43C(orf name)|uniprotkb:YCR725(orf name)|uniprotkb:YCR043C(locus name) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316979|imex:IM-14275-280 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000639|refseq:NP_009972.1|mint:P25361|ensemblfungi:YCR043C(gene)|ensemblfungi:YCR043C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0043332"(mating projection tip) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) - crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:bEMtsAa5vCsWqGOiXwBK40Pa0xQ559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:CFAA6EABB170A7B9|rigid:X8IpBhTqXl14sDuimGU2zO3WdvY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:P14359 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316968|imex:IM-14275-279 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) crc64:DBA26AF5B769C02A crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:7C0D6C2BAD7C72B3|rigid:skQeSHhz/VkqoysqL6CDrZf8ReQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28625 uniprotkb:P14359 intact:EBI-27313|uniprotkb:D6VZX3|ensemblfungi:YMR152W intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:yim1_yeast(display_long)|uniprotkb:YIM1(gene name)|psi-mi:YIM1(display_short)|uniprotkb:YM8520.01(orf name)|uniprotkb:YM9375.22(orf name)|uniprotkb:YMR152W(locus name) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317001|imex:IM-14275-282 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013872.1|sgd:S000004760|mint:P28625|dip:DIP-4467N|ensemblfungi:YMR152W(gene)|ensemblfungi:YMR152W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0018455"("alcohol dehydrogenase [NAD(P)+] activity")|interpro:IPR011032(GroES-like)|interpro:IPR036291 refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) - crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pbDN6nTnpBtIqdFE6/CjlI12o04559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:FA9C199E0CF6322B|rigid:Vnd78a6+rHGXBMAj3gIySvV+CnA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:P28321 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-26790|uniprotkb:D6VXJ4|ensemblfungi:YKL094W psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:mgll_yeast(display_long)|uniprotkb:YJU3(gene name)|psi-mi:YJU3(display_short)|uniprotkb:Monoacylglycerol hydrolase(gene name synonym)|uniprotkb:Monoacylglycerol lipase(gene name synonym)|uniprotkb:Serine hydrolase YJU3(gene name synonym)|uniprotkb:YKL441(orf name)|uniprotkb:YKL094W(locus name)|uniprotkb:Fatty acid ethyl ester hydrolase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6316990|imex:IM-14275-281 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD interpro:IPR022742|refseq:NP_012829.1|sgd:S000001577|mint:P28321|interpro:IPR029058|ensemblfungi:YKL094W(gene)|ensemblfungi:YKL094W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0071944"(cell periphery)|rcsb pdb:4ZWN|rcsb pdb:4ZXF psi-mi:"MI:0469"(intact) crc64:DBA26AF5B769C02A - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:IHpY1aez3MG+bn7bThCBdvE6KMw559292 intact-crc:666C145BBC99F95D|rigid:MnkkZ97Kff+ieZ4H2g7TFeG/WMk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:P14359 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317023|imex:IM-14275-284 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) - crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:222FC6B367DBDEF8|rigid:axiXsp8sWNTbeyJE/JM7AlRs7yU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32074 uniprotkb:P14359 intact:EBI-4891|ensemblfungi:YNL287W|uniprotkb:D6W0Q6 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:copg_yeast(display_long)|uniprotkb:SEC21(gene name)|psi-mi:SEC21(display_short)|uniprotkb:YNL287W(locus name)|uniprotkb:N0543(orf name)|uniprotkb:Gamma-coat protein(gene name synonym) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317012|imex:IM-14275-283 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|ensemblfungi:YNL287W(gene)|ensemblfungi:YNL287W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|refseq:NP_014112.1|sgd:S000005231|dip:DIP-1611N|mint:P32074|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) crc64:99DC7D737D4EF761 crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:uAs2hcx4DNS58qP1YDaUKgqZQm0559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:8188191A4892E323|rigid:Jzx8G/IxzyYyAIGfGj9/QqeMSks false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:P34110 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-20415|uniprotkb:D6VW33|ensemblfungi:YJL154C psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:vps35_yeast(display_long)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:Vacuolar protein-targeting protein 7(gene name synonym)|uniprotkb:VPT7(gene name synonym)|uniprotkb:J0580(orf name)|uniprotkb:YJL154C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317045|imex:IM-14275-286 author score:99.36 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD refseq:NP_012381.1|sgd:S000003690|ensemblfungi:YJL154C(gene)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1904377"(positive regulation of protein localization to cell periphery)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR042491|reactome:R-SCE-3238698|ensemblfungi:YJL154C_mRNA(transcript)|dip:DIP-1743N|mint:P34110 psi-mi:"MI:0469"(intact) crc64:DBA26AF5B769C02A crc64:DE1BC57B9DFB606E figure legend:tables S3 and S4|author-confidence:99.36|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:5KBi/lSF+BsMyg9ulP9eLCp2xCc559292 intact-crc:E67AB9109683529D|rigid:JxkAg4ZXVUuy/h6uHFnOo+M14mg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:P32610 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317034|imex:IM-14275-285 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610 psi-mi:"MI:0469"(intact) crc64:DBA26AF5B769C02A crc64:FDE93E1FAF0AEC5B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292 intact-crc:0B4A622E314B7F8C|rigid:TFyblhTMZvMuR+bVQjP39Sa3kXQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35196 uniprotkb:P14359 intact:EBI-14943|uniprotkb:D6VQ03|ensemblfungi:YBR002C intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:rer2_yeast(display_long)|uniprotkb:"Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific)"(gene name synonym)|uniprotkb:YBR0107(orf name)|uniprotkb:RER2(gene name)|psi-mi:RER2(display_short)|uniprotkb:YBR002C(locus name) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317067|imex:IM-14275-288 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036424|refseq:NP_009556.1|sgd:S000000206|interpro:IPR001441(Di-trans-poly-cis-decaprenylcistransferase)|interpro:IPR018520|ensemblfungi:YBR002C(gene)|ensemblfungi:YBR002C_mRNA(transcript)|go:"GO:0002094"(polyprenyltransferase activity)|go:"GO:0004659"(prenyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016094"(polyprenol biosynthetic process)|go:"GO:0019408"(dolichol biosynthetic process)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0045547"(dehydrodolichyl diphosphate synthase activity)|go:"GO:1904423"(dehydrodolichyl diphosphate synthase complex)|reactome:R-SCE-446199|mint:P35196 refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) - crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:gVl9E/6GKqKsUp/5VLdT5XGbjUM559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:B2ABB812C29E13B0|rigid:Mqzp1VFNWEk9XMuIqNCbBol5FyY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:P34163 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-19177|uniprotkb:D6VX56|ensemblfungi:YKL140W psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:tgl1_yeast(display_long)|uniprotkb:TGL1(gene name)|psi-mi:TGL1(display_short)|uniprotkb:YKL140W(locus name)|uniprotkb:YKL5(orf name)|uniprotkb:Triglyceride lipase-cholesterol esterase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317056|imex:IM-14275-287 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD refseq:NP_012782.1|sgd:S000001623|ensemblfungi:YKL140W(gene)|ensemblfungi:YKL140W_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR029058|dip:DIP-6306N|mint:P34163 psi-mi:"MI:0469"(intact) crc64:DBA26AF5B769C02A crc64:32D1F230701CB083 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:/f3560MDciadPqvZ0iY9e9oVBH8559292 intact-crc:102A299B0A667DFB|rigid:FzNesM7OEzXFgkW8WYy2mCmm16k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:P38225 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-6819|uniprotkb:O60021|uniprotkb:Q86ZS3|uniprotkb:D6VQ41|ensemblfungi:YBR041W psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:fat1_yeast(display_long)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:Very-long-chain acyl-CoA synthetase(gene name synonym)|uniprotkb:YBR0411(orf name)|uniprotkb:YBR041W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317089|imex:IM-14275-290 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD refseq:NP_009597.2|sgd:S000000245|mint:P38225|dip:DIP-5048N|ensemblfungi:YBR041W(gene)|ensemblfungi:YBR041W_mRNA(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0071944"(cell periphery)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR030310|interpro:IPR042099|reactome:R-SCE-159418|reactome:R-SCE-193368|reactome:R-SCE-193775|reactome:R-SCE-389599|reactome:R-SCE-6798695|reactome:R-SCE-804914|reactome:R-SCE-9033241 psi-mi:"MI:0469"(intact) crc64:DBA26AF5B769C02A crc64:509A5DEDDEE98823 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:mGjvEcQ/ZVHp/P+89KaQ7DrjcQg559292 intact-crc:8636D82B7FD7AEDC|rigid:ytOe2SOwvqGFrQU43ZZx92a7YCs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:P35844 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-9648|ensemblfungi:YPL145C|uniprotkb:D6W3M4|uniprotkb:E9P8U8 psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:kes1_yeast(display_long)|uniprotkb:KES1(gene name)|psi-mi:KES1(display_short)|uniprotkb:OSH4(gene name synonym)|uniprotkb:Protein KES1(gene name synonym)|uniprotkb:LPI3C(orf name)|uniprotkb:P2614(orf name)|uniprotkb:YPL145C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317078|imex:IM-14275-289 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD ensemblfungi:YPL145C(gene)|ensemblfungi:YPL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035621"(ER to Golgi ceramide transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|rcsb pdb:1ZHT|rcsb pdb:1ZHW|rcsb pdb:1ZHX|rcsb pdb:1ZHY|rcsb pdb:1ZHZ|rcsb pdb:1ZI7|rcsb pdb:3SPW|rcsb pdb:4F4B|rcsb pdb:4FES|rcsb pdb:4JCH|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_015180.1|sgd:S000006066|dip:DIP-2867N|mint:P35844 psi-mi:"MI:0469"(intact) crc64:DBA26AF5B769C02A - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:6vsHrA4RScGr2+xmii0wiuvK1OM559292 intact-crc:36DE995154FC229A|rigid:PWAdYyQozIHVVdQZyub99Pgjpc0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:P38604 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-6572|uniprotkb:Q92327|uniprotkb:D3DL21|ensemblfungi:YHR072W psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:erg7_yeast(display_long)|uniprotkb:Oxidosqualene--lanosterol cyclase(gene name synonym)|uniprotkb:2,3-epoxysqualene--lanosterol cyclase(gene name synonym)|uniprotkb:YHR072W(locus name)|uniprotkb:ERG7(gene name)|psi-mi:ERG7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317100|imex:IM-14275-291 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD refseq:NP_011939.2|sgd:S000001114|mint:P38604|dip:DIP-8319N|ensemblfungi:YHR072W(gene)|ensemblfungi:YHR072W_mRNA(transcript)|go:"GO:0000250"(lanosterol synthase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016104"(triterpenoid biosynthetic process)|go:"GO:0042300"(beta-amyrin synthase activity)|interpro:IPR002365(Terpene synthase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR018333|interpro:IPR032696|interpro:IPR032697|reactome:R-SCE-191273 psi-mi:"MI:0469"(intact) crc64:DBA26AF5B769C02A - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:zqDPA3GvKWkMTmH97TcdF8HOHBU559292 intact-crc:B675DFFF3AF08FE5|rigid:W7GYUgk97Sp49oNQ80b8A3OgSXU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39968 uniprotkb:P14359 intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317122|imex:IM-14275-293 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) crc64:B2E75774B47E5933 crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:AB1B0ED48797CD9E|rigid:jTUIUHEGMNwdJlcnhxq5d1wc4bY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39111 uniprotkb:P14359 intact:EBI-20272|uniprotkb:D6VUF5|ensemblfungi:YGR020C intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:vatf_yeast(display_long)|uniprotkb:VMA7(gene name)|psi-mi:VMA7(display_short)|uniprotkb:YGR020C(locus name)|uniprotkb:Vacuolar proton pump subunit F(gene name synonym)|uniprotkb:V-ATPase 14 kDa subunit(gene name synonym) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317111|imex:IM-14275-292 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011534.1|sgd:S000003252|ensemblfungi:YGR020C(gene)|ensemblfungi:YGR020C_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016020"(membrane)|go:"GO:0042625"(ATPase-coupled ion transmembrane transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005772(ATPase, V1 complex, subunit F, eukaryotic)|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|interpro:IPR036906|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4IX9|rcsb pdb:4RND|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2077N|mint:P39111 refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) crc64:D21EC0980EB99DFF crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VtthQl2jj9fpjv3psX0YUNbIAKU559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:A57E8E3A26098354|rigid:oA6ho1La3F0Eu4VpJmhvVXa3tV8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:P40471 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-25213|uniprotkb:D6VVG3|ensemblfungi:YIL124W psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:ayr1_yeast(display_long)|uniprotkb:AYR1(gene name)|psi-mi:AYR1(display_short)|uniprotkb:Acylglycerone-phosphate reductase(gene name synonym)|uniprotkb:1-acyl DHAP reductase(gene name synonym)|uniprotkb:Acyl/alkyl DHAP reductase(gene name synonym)|uniprotkb:GBG1(gene name synonym)|uniprotkb:Triacylglycerol lipase AYR1(gene name synonym)|uniprotkb:YIL124W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317144|imex:IM-14275-295 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD sgd:S000001386|refseq:NP_012142.3|mint:P40471|dip:DIP-4614N|ensemblfungi:YIL124W(gene)|ensemblfungi:YIL124W_mRNA(transcript)|go:"GO:0000140"(acylglycerone-phosphate reductase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0102566"(1-acyl dihydroxyacetone phosphate reductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291 psi-mi:"MI:0469"(intact) crc64:DBA26AF5B769C02A crc64:B614C0E0B1FB0CE0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:WE4RmSXARj683MNUEsYGLis36Xo559292 intact-crc:E760DE493A162E4C|rigid:v1xgOcZqttmXnTXHvt3dEG3BCqs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40094 uniprotkb:P14359 intact:EBI-16605|ensemblfungi:YER157W|uniprotkb:D3DM64 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:cog3_yeast(display_long)|uniprotkb:COG3(gene name)|psi-mi:COG3(display_short)|uniprotkb:GRD20(gene name synonym)|uniprotkb:SEC34(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 3(gene name synonym)|uniprotkb:Protein SEC34(gene name synonym)|uniprotkb:YER157W(locus name) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317133|imex:IM-14275-294 author score:99.34 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER157W(gene)|ensemblfungi:YER157W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR007265(Sec34-like protein)|refseq:NP_011084.1|sgd:S000000959|dip:DIP-4728N|mint:P40094 refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) crc64:C7AFBE99010FE571 crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:99.34|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R2r0ZW+nxrykdTHq1cJy9zOmvHo559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:E6421BA0415805AD|rigid:dWiHu962YT757YId7rePmiGQdjA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:P40582 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-7941|uniprotkb:D6VVW9|ensemblfungi:YIR038C psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:gst1_yeast(display_long)|uniprotkb:YIR038C(locus name)|uniprotkb:GTT1(gene name)|psi-mi:GTT1(display_short)|uniprotkb:GST-I(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317166|imex:IM-14275-297 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD refseq:NP_012304.1|sgd:S000001477|mint:P40582|dip:DIP-2103N|ensemblfungi:YIR038C(gene)|ensemblfungi:YIR038C_mRNA(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010731"(protein glutathionylation)|go:"GO:0071944"(cell periphery)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079 psi-mi:"MI:0469"(intact) crc64:DBA26AF5B769C02A crc64:3C07D40D29F60DFF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:+bqzHpsoLw4j2qQBzHbkfldR5OU559292 intact-crc:84997BF29CFA862C|rigid:CjXgbEr2+ZULd/uPs8WLHIcSJ9M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40540 uniprotkb:P14359 intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317155|imex:IM-14275-296 author score:99.37 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) crc64:6DBEEEE7722203B0 crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:99.37|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:946C531B7EAA490E|rigid:1K5OREYp9TOAKMa5YagN1YtiJJ8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41810 uniprotkb:P14359 intact:EBI-4869|uniprotkb:Q03779|uniprotkb:D6VSL9|ensemblfungi:YDR238C intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:copb_yeast(display_long)|uniprotkb:SEC26(gene name)|psi-mi:SEC26(display_short)|uniprotkb:YDR238C(locus name)|uniprotkb:YD8419.05C(orf name)|uniprotkb:Beta-coat protein(gene name synonym) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317188|imex:IM-14275-299 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002646|refseq:NP_010524.3|dip:DIP-6467N|mint:P41810|ensemblfungi:YDR238C(gene)|ensemblfungi:YDR238C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|reactome:R-SCE-6798695|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) crc64:885420DB026BCFA3 crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZfLp1BUmvVuTiXn7/Zbf/3m6VtE559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:A7689126079CD78B|rigid:d4B3PaPvKVUpljLGQBQJG+f0Avg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41807 uniprotkb:P14359 intact:EBI-20281|uniprotkb:D6W446|ensemblfungi:YPR036W intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:vath_yeast(display_long)|uniprotkb:YP3085.02(orf name)|uniprotkb:VMA13(gene name)|psi-mi:VMA13(display_short)|uniprotkb:CLS11(gene name synonym)|uniprotkb:YPR036W(locus name)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 54 kDa subunit(gene name synonym) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317177|imex:IM-14275-298 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015361.1|sgd:S000006240|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|rcsb pdb:1HO8|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YPR036W(gene)|ensemblfungi:YPR036W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|dip:DIP-6640N|mint:P41807 refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) crc64:54131FF9C2C87594 crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kEXWvOsnTk0WdgGOny+mufz4lTo559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:681819DFD874B87B|rigid:mpfZXkxjevxsPo7Sre6fG1AT+G8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:P41811 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317199|imex:IM-14275-300 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:DBA26AF5B769C02A crc64:6A5E50BBEB02CB58 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:38D19A00226889DF|rigid:9L2GHQ3H3yKhQAlUSu/cU5SuFOE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:P43621 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-4876|uniprotkb:D6VTT4|ensemblfungi:YFR051C psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:copd_yeast(display_long)|uniprotkb:RET2(gene name)|psi-mi:RET2(display_short)|uniprotkb:YFR051C(locus name)|uniprotkb:Delta-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317210|imex:IM-14275-301 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD sgd:S000001947|refseq:NP_116709.3|dip:DIP-5255N|mint:P43621|ensemblfungi:YFR051C(gene)|ensemblfungi:YFR051C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|rcsb pdb:5FJW|rcsb pdb:5FJX|rcsb pdb:5FJZ|rcsb pdb:5FK0|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:DBA26AF5B769C02A crc64:AA730F046655EE5A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:auvjuT8ffm1R4P3mRKEIWAsynW0559292 intact-crc:0D22CFFC59F52AED|rigid:bRUxWyPNxXJt/jAwhZF+thc8dyM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:P50276 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317221|imex:IM-14275-302 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) crc64:DBA26AF5B769C02A - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:DB4793ACA6B662FD|rigid:/xjtl8HNSwD/4vJWXQSagCRpmhk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02205 uniprotkb:P14359 intact:EBI-27062|uniprotkb:D6VX73|ensemblfungi:YKR007W intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:meh1_yeast(display_long)|uniprotkb:GSE complex subunit 2(gene name synonym)|uniprotkb:EGO complex subunit 1(gene name synonym)|uniprotkb:YKR007W(locus name)|uniprotkb:YK106(orf name)|uniprotkb:MEH1(gene name)|psi-mi:MEH1(display_short)|uniprotkb:EGO1(gene name synonym)|uniprotkb:GSE2(gene name synonym) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317232|imex:IM-14275-303 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001715|refseq:NP_012932.1|mint:Q02205|dip:DIP-1922N|ensemblfungi:YKR007W(gene)|ensemblfungi:YKR007W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0005829"(cytosol)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007040"(lysosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR028209|rcsb pdb:4XPM|rcsb pdb:6JWP refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) crc64:995DD1E68331D050 crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:73a6e5W5wQixGg2aGXDo4A6NR2s559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:67ACAC3338479F65|rigid:UZ5b+JjQStEIOteSpRxpw7i2iYE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:Q02785 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317243|imex:IM-14275-304 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) crc64:DBA26AF5B769C02A - figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:BF4156572ED68FB2|rigid:4eyrVYN5uQ+4HvSEo4einVFJujQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04228 uniprotkb:P14359 intact:EBI-27730|uniprotkb:D6VZG1|ensemblfungi:YML013W intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:ubx2_yeast(display_long)|uniprotkb:SEL1(gene name synonym)|uniprotkb:YM9571.05(orf name)|uniprotkb:YML013W(locus name)|uniprotkb:UBX2(gene name)|psi-mi:UBX2(display_short)|uniprotkb:Secretion lowering protein 1(gene name synonym) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317254|imex:IM-14275-305 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013699.1|sgd:S000004475|dip:DIP-5073N|mint:Q04228|ensemblfungi:YML013W(gene)|ensemblfungi:YML013W_mRNA(transcript)|go:"GO:0000837"(Doa10p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001012(UBX) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) crc64:DA4DDD3D624C17B8 crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pHZ9MnjC5Y3aC5hV43Z4fmkqI8w559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:7801540B7FB176A5|rigid:irQo9Vz1/RvxdcBY4S0dRJWilac false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06508 uniprotkb:P14359 intact:EBI-36961|uniprotkb:D6W4D7|ensemblfungi:YPR139C intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:loa1_yeast(display_long)|uniprotkb:LOA1(gene name)|psi-mi:LOA1(display_short)|uniprotkb:VPS66(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 66(gene name synonym)|uniprotkb:YPR139C(locus name) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317265|imex:IM-14275-306 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006343|refseq:NP_015465.1|mint:Q06508|ensemblfungi:YPR139C(gene)|ensemblfungi:YPR139C_mRNA(transcript)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0042171"(lysophosphatidic acid acyltransferase activity)|reactome:R-SCE-1482788|reactome:R-SCE-1482801|reactome:R-SCE-1482839|reactome:R-SCE-1482925|reactome:R-SCE-1483166|reactome:R-SCE-6798695 refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) - crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:JtPDp92PFuE5D2WsKzyeKeXs95c559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:D9761A8D701E2B9F|rigid:Pbt0oUqogQ1OQc5y4uFJGFa6N4E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:Q12168 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-32973|uniprotkb:Q07268|uniprotkb:D6VYD8|ensemblfungi:YLR144C psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:eng2_yeast(display_long)|uniprotkb:ACF2(gene name)|psi-mi:ACF2(display_short)|uniprotkb:YLR144C(locus name)|uniprotkb:Laminarinase-2(gene name synonym)|uniprotkb:ENG2(gene name synonym)|uniprotkb:PCA1(gene name synonym)|uniprotkb:L3180(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317276|imex:IM-14275-307 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD refseq:NP_013245.1|sgd:S000004134|mint:Q12168|dip:DIP-2889N|ensemblfungi:YLR144C(gene)|ensemblfungi:YLR144C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042973"(glucan endo-1,3-beta-D-glucosidase activity)|go:"GO:0052861"(glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group)|go:"GO:0052862"(glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group)|interpro:IPR005200(Glycoside hydrolase, family 81)|interpro:IPR040451|interpro:IPR040720 psi-mi:"MI:0469"(intact) crc64:DBA26AF5B769C02A - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:8STCUe6Ie2CnTTBMjY8wrld5h44559292 intact-crc:9CE41B1C33CF163A|rigid:R+MZVxQHCMw/zLcsCK/DEh7hwTo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14693 uniprotkb:P0C268 intact:EBI-24602|uniprotkb:D3DL34|ensemblfungi:YHR083W intact:EBI-2044092|uniprotkb:D6VPV9|ensemblfungi:YBL039W-B psi-mi:sam35_yeast(display_long)|uniprotkb:YHR083W(locus name)|uniprotkb:SAM35(gene name)|psi-mi:SAM35(display_short)|uniprotkb:OMP85(gene name synonym)|uniprotkb:TOB38(gene name synonym)|uniprotkb:TOM38(gene name synonym)|uniprotkb:TOB complex 38 kDa subunit(gene name synonym)|uniprotkb:Mitochondrial 38 kDa outer membrane protein(gene name synonym) psi-mi:yb39b_yeast(display_long)|uniprotkb:YBL039W-B(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317298|imex:IM-14275-309 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011951.1|sgd:S000001125|dip:DIP-1879N|mint:P14693|ensemblfungi:YHR083W_mRNA(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0070096"(mitochondrial outer membrane translocase complex assembly)|interpro:IPR021211|rcsb pdb:7BTW|rcsb pdb:7BTX|rcsb pdb:7BTY|ensemblfungi:YHR083W(gene) sgd:S000028517|refseq:NP_878045.1|mint:P0C268|ensemblfungi:YBL039W-B(gene)|ensemblfungi:YBL039W-B_mRNA(transcript)|go:"GO:0005777"(peroxisome) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:NetfrtErWuBipcsdLZvTy/rTS80559292 rogid:EfowKSHyZ6Fgw3vWQ74mzPwXTbQ559292 intact-crc:72BA9ABA88E61DB1|rigid:6QQ0IKOtlwc5t/YNQ6eVZodoRIU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12452 uniprotkb:P14359 intact:EBI-38132|uniprotkb:D6VYA1|ensemblfungi:YLR100W intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:erg27_yeast(display_long)|uniprotkb:ERG27(gene name)|psi-mi:ERG27(display_short)|uniprotkb:YLR100W(locus name) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317287|imex:IM-14275-308 author score:95.97 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013201.1|sgd:S000004090|mint:Q12452|dip:DIP-1237N|ensemblfungi:YLR100W(gene)|ensemblfungi:YLR100W_mRNA(transcript)|go:"GO:0000253"(3-keto sterol reductase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006696"(ergosterol biosynthetic process)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|interpro:IPR038765|interpro:IPR042829 refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) crc64:D9A0589C049D8C49 crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:95.97|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:O7stXbO9C0tvqJH/yjFPDMjib64559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:5FAEA2111115F6F3|rigid:AV+FAbH840pw57m6pt3sj9KrKJ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14693 uniprotkb:P54783 intact:EBI-24602|uniprotkb:D3DL34|ensemblfungi:YHR083W intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:sam35_yeast(display_long)|uniprotkb:YHR083W(locus name)|uniprotkb:SAM35(gene name)|psi-mi:SAM35(display_short)|uniprotkb:OMP85(gene name synonym)|uniprotkb:TOB38(gene name synonym)|uniprotkb:TOM38(gene name synonym)|uniprotkb:TOB complex 38 kDa subunit(gene name synonym)|uniprotkb:Mitochondrial 38 kDa outer membrane protein(gene name synonym) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317309|imex:IM-14275-310 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011951.1|sgd:S000001125|dip:DIP-1879N|mint:P14693|ensemblfungi:YHR083W_mRNA(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0070096"(mitochondrial outer membrane translocase complex assembly)|interpro:IPR021211|rcsb pdb:7BTW|rcsb pdb:7BTX|rcsb pdb:7BTY|ensemblfungi:YHR083W(gene) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:NetfrtErWuBipcsdLZvTy/rTS80559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:F34ED0A5B2E09089|rigid:sFVa/IQN7qjJ94JPE4cLWbldLHQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P12754 uniprotkb:P14741 intact:EBI-6265|uniprotkb:D6VUL5|ensemblfungi:YGR083C intact:EBI-6253|uniprotkb:D6VX91|ensemblfungi:YKR026C psi-mi:ei2bd_yeast(display_long)|uniprotkb:GCD2(gene name)|psi-mi:GCD2(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym)|uniprotkb:GCD complex subunit GCD2(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD2(gene name synonym)|uniprotkb:TIF224(gene name synonym)|uniprotkb:YGR083C(locus name) psi-mi:ei2ba_yeast(display_long)|uniprotkb:GCN3(gene name)|psi-mi:GCN3(display_short)|uniprotkb:AAS2(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym)|uniprotkb:GCD complex subunit GCN3(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCN3(gene name synonym)|uniprotkb:TIF221(gene name synonym)|uniprotkb:YKR026C(locus name)|uniprotkb:Translational activator GCN3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317320|imex:IM-14275-311 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011597.1|sgd:S000003315|dip:DIP-2343N|mint:P12754|ensemblfungi:YGR083C(gene)|ensemblfungi:YGR083C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_012951.1|sgd:S000001734|dip:DIP-1328N|mint:P14741|ensemblfungi:YKR026C(gene)|ensemblfungi:YKR026C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 psi-mi:"MI:0469"(intact) crc64:B188457543CE1AAE crc64:8E9A928D6D56E12B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:q04UNg7w1BfegEmJy01O+BDTJno559292 rogid:Nm+Ahop9EG8SQNZbo6+usIB9SAY559292 intact-crc:66A5EFB8354F0226|rigid:90h1jU4PMqKIhqeI4C44wt9QQ90 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15019 uniprotkb:Q06142 intact:EBI-18952|uniprotkb:D6VYZ2|ensemblfungi:YLR354C intact:EBI-9145|ensemblfungi:YLR347C|uniprotkb:D6VYY6 psi-mi:tal1_yeast(display_long)|uniprotkb:L9638.6(orf name)|uniprotkb:YLR354C(locus name)|uniprotkb:TAL1(gene name)|psi-mi:TAL1(display_short) psi-mi:imb1_yeast(display_long)|uniprotkb:KAP95(gene name)|psi-mi:KAP95(display_short)|uniprotkb:YLR347C(locus name)|uniprotkb:L8300.15(orf name)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Karyopherin-95(gene name synonym)|uniprotkb:Importin-95(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317331|imex:IM-14275-312 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR354C(gene)|ensemblfungi:YLR354C_mRNA(transcript)|go:"GO:0004801"(transaldolase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|interpro:IPR001585(Transaldolase)|interpro:IPR004730(Transaldolase AB)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR018225|reactome:R-SCE-163754|reactome:R-SCE-71336|refseq:NP_013458.1|sgd:S000004346|dip:DIP-4980N|mint:P15019 rcsb pdb:3EA5|rcsb pdb:3ND2|rcsb pdb:5OWU|reactome:R-SCE-2995383|reactome:R-SCE-6798695|ensemblfungi:YLR347C(gene)|ensemblfungi:YLR347C_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|rcsb pdb:2BKU|go:"GO:0006612"(protein targeting to membrane)|refseq:NP_013451.1|sgd:S000004339|dip:DIP-2357N|mint:Q06142 psi-mi:"MI:0469"(intact) crc64:2A3A96D80E22B157 crc64:ED530F5313E75B06 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:JboC+JzVe+go2+Tk5tnWqKG3ELk559292 rogid:ebWeXaUKiBFWgjdv9s2pz1GIqgI559292 intact-crc:20B89039B2A3066F|rigid:yIQqleZfxCvAHKNFVZ9tl2BO2nA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15274 uniprotkb:P15274 intact:EBI-2548|uniprotkb:D6VZE0|ensemblfungi:YML035C intact:EBI-2548|uniprotkb:D6VZE0|ensemblfungi:YML035C psi-mi:ampd_yeast(display_long)|uniprotkb:AMD1(gene name)|psi-mi:AMD1(display_short)|uniprotkb:AMD(gene name synonym)|uniprotkb:Myoadenylate deaminase(gene name synonym)|uniprotkb:YML035C(locus name) psi-mi:ampd_yeast(display_long)|uniprotkb:AMD1(gene name)|psi-mi:AMD1(display_short)|uniprotkb:AMD(gene name synonym)|uniprotkb:Myoadenylate deaminase(gene name synonym)|uniprotkb:YML035C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317342|imex:IM-14275-313 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013677.1|sgd:S000004498|dip:DIP-1949N|mint:P15274|ensemblfungi:YML035C(gene)|ensemblfungi:YML035C_mRNA(transcript)|go:"GO:0003876"(AMP deaminase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006163"(purine nucleotide metabolic process)|go:"GO:0006178"(guanine salvage)|go:"GO:0006188"(IMP biosynthetic process)|go:"GO:0032264"(IMP salvage)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR001365(Adenosine/AMP deaminase)|interpro:IPR006329(AMP deaminase)|interpro:IPR006650(Adenosine/AMP deaminase active site)|interpro:IPR032466|reactome:R-SCE-6798695|reactome:R-SCE-74217 refseq:NP_013677.1|sgd:S000004498|dip:DIP-1949N|mint:P15274|ensemblfungi:YML035C(gene)|ensemblfungi:YML035C_mRNA(transcript)|go:"GO:0003876"(AMP deaminase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006163"(purine nucleotide metabolic process)|go:"GO:0006178"(guanine salvage)|go:"GO:0006188"(IMP biosynthetic process)|go:"GO:0032264"(IMP salvage)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR001365(Adenosine/AMP deaminase)|interpro:IPR006329(AMP deaminase)|interpro:IPR006650(Adenosine/AMP deaminase active site)|interpro:IPR032466|reactome:R-SCE-6798695|reactome:R-SCE-74217 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:bdsLZHhChz/aUREXidSHqge1xcM559292 rogid:bdsLZHhChz/aUREXidSHqge1xcM559292 intact-crc:F21AE00664B03DD0|rigid:Iregv8qL9ntivvc5zo0VQCjmeXo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15365 uniprotkb:P38264 intact:EBI-5527|uniprotkb:D6VWX1|ensemblfungi:YJR152W intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 psi-mi:dal5_yeast(display_long)|uniprotkb:DAL5(gene name)|psi-mi:DAL5(display_short)|uniprotkb:UREP1(gene name synonym)|uniprotkb:YJR152W(locus name)|uniprotkb:J2230(orf name) psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317364|imex:IM-14275-315 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003913|refseq:NP_012686.3|dip:DIP-7873N|mint:P15365|ensemblfungi:YJR152W(gene)|ensemblfungi:YJR152W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015124"(allantoate transmembrane transporter activity)|go:"GO:0015719"(allantoate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0042938"(dipeptide transport)|go:"GO:0042939"(tripeptide transport)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Y2kCv3dK4Hjn9hJpK+WK5rp6VKU559292 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 intact-crc:9CACD877D1590CFC|rigid:tm9yLP67Begn4mvOQ+Vn/TlbMsw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15365 uniprotkb:P10614 intact:EBI-5527|uniprotkb:D6VWX1|ensemblfungi:YJR152W intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:dal5_yeast(display_long)|uniprotkb:DAL5(gene name)|psi-mi:DAL5(display_short)|uniprotkb:UREP1(gene name synonym)|uniprotkb:YJR152W(locus name)|uniprotkb:J2230(orf name) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317353|imex:IM-14275-314 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003913|refseq:NP_012686.3|dip:DIP-7873N|mint:P15365|ensemblfungi:YJR152W(gene)|ensemblfungi:YJR152W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015124"(allantoate transmembrane transporter activity)|go:"GO:0015719"(allantoate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0042938"(dipeptide transport)|go:"GO:0042939"(tripeptide transport)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Y2kCv3dK4Hjn9hJpK+WK5rp6VKU559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:A092214F69B7705F|rigid:4tV/MH3TYwvJKYD78GqYEO4YEuw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40540 uniprotkb:P15365 intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C intact:EBI-5527|uniprotkb:D6VWX1|ensemblfungi:YJR152W psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:dal5_yeast(display_long)|uniprotkb:DAL5(gene name)|psi-mi:DAL5(display_short)|uniprotkb:UREP1(gene name synonym)|uniprotkb:YJR152W(locus name)|uniprotkb:J2230(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317375|imex:IM-14275-316 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX sgd:S000003913|refseq:NP_012686.3|dip:DIP-7873N|mint:P15365|ensemblfungi:YJR152W(gene)|ensemblfungi:YJR152W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015124"(allantoate transmembrane transporter activity)|go:"GO:0015719"(allantoate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0042938"(dipeptide transport)|go:"GO:0042939"(tripeptide transport)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:6DBEEEE7722203B0 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 rogid:Y2kCv3dK4Hjn9hJpK+WK5rp6VKU559292 intact-crc:6435AE9D6D476403|rigid:1evn3IJa8sefPo/Kd5aRIP6nT2c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15705 uniprotkb:P07259 intact:EBI-18418|uniprotkb:D6W293|ensemblfungi:YOR027W intact:EBI-14372|uniprotkb:A2TBN0|uniprotkb:Q06HN1|uniprotkb:D6VW55|ensemblfungi:YJL130C psi-mi:sti1_yeast(display_long)|uniprotkb:STI1(gene name)|psi-mi:STI1(display_short)|uniprotkb:OR26.17(orf name)|uniprotkb:YOR027W(locus name) psi-mi:pyr1_yeast(display_long)|uniprotkb:J0686(orf name)|uniprotkb:YJL130C(locus name)|uniprotkb:URA2(gene name)|psi-mi:URA2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317386|imex:IM-14275-317 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014670.1|sgd:S000005553|ensemblfungi:YOR027W(gene)|ensemblfungi:YOR027W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008104"(protein localization)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR041243|rcsb pdb:2LLV|rcsb pdb:2LLW|rcsb pdb:3UPV|rcsb pdb:3UQ3|reactome:R-SCE-3371497|reactome:R-SCE-9696273|dip:DIP-2329N|mint:P15705 refseq:NP_012405.2|sgd:S000003666|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016597"(amino acid binding)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0045984"(negative regulation of pyrimidine nucleobase metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|ensemblfungi:YJL130C(gene)|ensemblfungi:YJL130C_mRNA(transcript)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR032466|interpro:IPR035686|interpro:IPR036480|interpro:IPR036901|interpro:IPR036914|interpro:IPR036897|reactome:R-SCE-500753|mint:P07259|dip:DIP-7215N psi-mi:"MI:0469"(intact) crc64:CF8A85C2BBD3C44C crc64:D5A47F4E42A9B1A7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+w2ibiXXPwvtcC3RxknGi0ELvvE559292 rogid:gc7xepqIGcYGssYFCLBvLnTogPE559292 intact-crc:8F6A3F6A4147E9A0|rigid:y07w88q0CWJZlHgdOOEhfTo7ayE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15705 uniprotkb:P15705 intact:EBI-18418|uniprotkb:D6W293|ensemblfungi:YOR027W intact:EBI-18418|uniprotkb:D6W293|ensemblfungi:YOR027W psi-mi:sti1_yeast(display_long)|uniprotkb:STI1(gene name)|psi-mi:STI1(display_short)|uniprotkb:OR26.17(orf name)|uniprotkb:YOR027W(locus name) psi-mi:sti1_yeast(display_long)|uniprotkb:STI1(gene name)|psi-mi:STI1(display_short)|uniprotkb:OR26.17(orf name)|uniprotkb:YOR027W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317397|imex:IM-14275-318 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014670.1|sgd:S000005553|ensemblfungi:YOR027W(gene)|ensemblfungi:YOR027W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008104"(protein localization)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR041243|rcsb pdb:2LLV|rcsb pdb:2LLW|rcsb pdb:3UPV|rcsb pdb:3UQ3|reactome:R-SCE-3371497|reactome:R-SCE-9696273|dip:DIP-2329N|mint:P15705 refseq:NP_014670.1|sgd:S000005553|ensemblfungi:YOR027W(gene)|ensemblfungi:YOR027W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008104"(protein localization)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR041243|rcsb pdb:2LLV|rcsb pdb:2LLW|rcsb pdb:3UPV|rcsb pdb:3UQ3|reactome:R-SCE-3371497|reactome:R-SCE-9696273|dip:DIP-2329N|mint:P15705 psi-mi:"MI:0469"(intact) crc64:CF8A85C2BBD3C44C crc64:CF8A85C2BBD3C44C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+w2ibiXXPwvtcC3RxknGi0ELvvE559292 rogid:+w2ibiXXPwvtcC3RxknGi0ELvvE559292 intact-crc:915C0048365EA02E|rigid:zoIAOExv0uhIe9TXSXyu//Wjbes false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22137 uniprotkb:P15705 intact:EBI-4766|uniprotkb:D6VTU9|ensemblfungi:YGL206C intact:EBI-18418|uniprotkb:D6W293|ensemblfungi:YOR027W psi-mi:clh_yeast(display_long)|uniprotkb:CHC1(gene name)|psi-mi:CHC1(display_short)|uniprotkb:YGL206C(locus name) psi-mi:sti1_yeast(display_long)|uniprotkb:STI1(gene name)|psi-mi:STI1(display_short)|uniprotkb:OR26.17(orf name)|uniprotkb:YOR027W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317408|imex:IM-14275-319 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011309.1|sgd:S000003174|dip:DIP-2279N|mint:P22137|ensemblfungi:YGL206C(gene)|ensemblfungi:YGL206C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0071439"(clathrin complex)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-432720|reactome:R-SCE-437239|reactome:R-SCE-8856828|reactome:R-SCE-8866427|reactome:R-SCE-8964038 refseq:NP_014670.1|sgd:S000005553|ensemblfungi:YOR027W(gene)|ensemblfungi:YOR027W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008104"(protein localization)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR041243|rcsb pdb:2LLV|rcsb pdb:2LLW|rcsb pdb:3UPV|rcsb pdb:3UQ3|reactome:R-SCE-3371497|reactome:R-SCE-9696273|dip:DIP-2329N|mint:P15705 psi-mi:"MI:0469"(intact) crc64:622F3083DF2FE315 crc64:CF8A85C2BBD3C44C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SAN6H3nVFozXZyTiRLaljMcIKIA559292 rogid:+w2ibiXXPwvtcC3RxknGi0ELvvE559292 intact-crc:D2256BE2E2F633CF|rigid:ZX5zbXgmoTJYTr00C57ZcOE5Mjg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15705 uniprotkb:Q08446 intact:EBI-18418|uniprotkb:D6W293|ensemblfungi:YOR027W intact:EBI-17070|ensemblfungi:YOR057W|uniprotkb:D6W2C0|uniprotkb:E9P8U7 psi-mi:sti1_yeast(display_long)|uniprotkb:STI1(gene name)|psi-mi:STI1(display_short)|uniprotkb:OR26.17(orf name)|uniprotkb:YOR027W(locus name) psi-mi:sgt1_yeast(display_long)|uniprotkb:SGT1(gene name)|psi-mi:SGT1(display_short)|uniprotkb:YOR057W(locus name)|uniprotkb:YOR29-08(orf name)|uniprotkb:Suppressor of G2 allele of SKP1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317419|imex:IM-14275-320 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014670.1|sgd:S000005553|ensemblfungi:YOR027W(gene)|ensemblfungi:YOR027W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008104"(protein localization)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR041243|rcsb pdb:2LLV|rcsb pdb:2LLW|rcsb pdb:3UPV|rcsb pdb:3UQ3|reactome:R-SCE-3371497|reactome:R-SCE-9696273|dip:DIP-2329N|mint:P15705 refseq:NP_014700.1|sgd:S000005583|ensemblfungi:YOR057W(gene)|ensemblfungi:YOR057W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0007049"(cell cycle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034622"|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044563|rcsb pdb:5AN3|reactome:R-SCE-844456|dip:DIP-1628N|mint:Q08446 psi-mi:"MI:0469"(intact) crc64:CF8A85C2BBD3C44C crc64:5DE65874BE155552 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+w2ibiXXPwvtcC3RxknGi0ELvvE559292 rogid:DJ37U8QHPE7Wi/+kOiEwCg1mxCw559292 intact-crc:ABDCD7F74627C006|rigid:xVC0TmQ8EHgoBBqhF3pTy4sR8Pg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15790 uniprotkb:P43639 intact:EBI-9533|ensemblfungi:YIL035C|uniprotkb:D6VVP7 intact:EBI-9563|uniprotkb:Q9URG5|ensemblfungi:YGL019W|uniprotkb:D6VUB8 psi-mi:csk21_yeast(display_long)|uniprotkb:YIL035C(locus name)|uniprotkb:CKA1(gene name)|psi-mi:CKA1(display_short) psi-mi:csk2b_yeast(display_long)|uniprotkb:CKB1(gene name)|psi-mi:CKB1(display_short)|uniprotkb:YGL019W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317430|imex:IM-14275-321 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012229.1|sgd:S000001297|ensemblfungi:YIL035C(gene)|ensemblfungi:YIL035C_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007535"(donor selection)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0034456"(UTP-C complex)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:4FI1|rcsb pdb:4JQE|rcsb pdb:4JR7|rcsb pdb:4LFI|rcsb pdb:4MWH|reactome:R-SCE-2514853|reactome:R-SCE-6804756|reactome:R-SCE-8934903|reactome:R-SCE-8948751|mint:P15790|dip:DIP-48N ensemblfungi:YGL019W(gene)|ensemblfungi:YGL019W_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0034456"(UTP-C complex)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR035991|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|refseq:NP_011496.3|sgd:S000002987|mint:P43639|dip:DIP-282N psi-mi:"MI:0469"(intact) crc64:6A1A7F1BF47250C9 crc64:9ACA8D285E6990AF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SNrrYvyWdzd6bAyvluPlZqs5WJw559292 rogid:etfQ7p1F805HcUhV/Uiv9TPtejU559292 intact-crc:987A448631CBADBE|rigid:CBVMW3krEAcKWK84ijWYT8wM2UY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15807 uniprotkb:P15807 intact:EBI-10770|ensemblfungi:YBR213W|uniprotkb:D6VQK9 intact:EBI-10770|ensemblfungi:YBR213W|uniprotkb:D6VQK9 psi-mi:met8_yeast(display_long)|uniprotkb:YBR1461(orf name)|uniprotkb:YBR213W(locus name)|uniprotkb:MET8(gene name)|psi-mi:MET8(display_short) psi-mi:met8_yeast(display_long)|uniprotkb:YBR1461(orf name)|uniprotkb:YBR213W(locus name)|uniprotkb:MET8(gene name)|psi-mi:MET8(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317441|imex:IM-14275-322 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBR213W(gene)|ensemblfungi:YBR213W_mRNA(transcript)|go:"GO:0000103"(sulfate assimilation)|go:"GO:0004325"(ferrochelatase activity)|go:"GO:0019354"(siroheme biosynthetic process)|go:"GO:0043115"(precorrin-2 dehydrogenase activity)|go:"GO:0051266"(sirohydrochlorin ferrochelatase activity)|interpro:IPR028161|interpro:IPR028162|interpro:IPR028281|interpro:IPR036291|rcsb pdb:1KYQ|refseq:NP_009772.1|sgd:S000000417|mint:P15807|dip:DIP-4944N ensemblfungi:YBR213W(gene)|ensemblfungi:YBR213W_mRNA(transcript)|go:"GO:0000103"(sulfate assimilation)|go:"GO:0004325"(ferrochelatase activity)|go:"GO:0019354"(siroheme biosynthetic process)|go:"GO:0043115"(precorrin-2 dehydrogenase activity)|go:"GO:0051266"(sirohydrochlorin ferrochelatase activity)|interpro:IPR028161|interpro:IPR028162|interpro:IPR028281|interpro:IPR036291|rcsb pdb:1KYQ|refseq:NP_009772.1|sgd:S000000417|mint:P15807|dip:DIP-4944N psi-mi:"MI:0469"(intact) crc64:0EE9A6DE8A43673E crc64:0EE9A6DE8A43673E figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4Z2yZage0Yi6KB2YM/gANFSLcC0559292 rogid:4Z2yZage0Yi6KB2YM/gANFSLcC0559292 intact-crc:45E55AEA6FBC23CC|rigid:48WVKQTG3exJlH7zGMjdkpKxluE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16370 uniprotkb:P38902 intact:EBI-15773|ensemblfungi:YIL021W|uniprotkb:D6VVQ8 intact:EBI-15806|ensemblfungi:YOL005C|uniprotkb:D6W262 psi-mi:rpb3_yeast(display_long)|uniprotkb:YIL021W(locus name)|uniprotkb:RPB3(gene name)|psi-mi:RPB3(display_short)|uniprotkb:DNA-directed RNA polymerase II 45 kDa polypeptide(gene name synonym)|uniprotkb:B44.5(gene name synonym) psi-mi:rpb11_yeast(display_long)|uniprotkb:YOL005C(locus name)|uniprotkb:RPB11(gene name)|psi-mi:RPB11(display_short)|uniprotkb:DNA-directed RNA polymerase II 13.6 kDa polypeptide(gene name synonym)|uniprotkb:B13.6(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317463|imex:IM-14275-324 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001283|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3RZD|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:5C4A|rcsb pdb:7KEF|rcsb pdb:6UPY|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|rcsb pdb:6UPZ|reactome:R-SCE-674695|rcsb pdb:6UQ0|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|rcsb pdb:6UQ1|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|ensemblfungi:YIL021W(gene)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|ensemblfungi:YIL021W_mRNA(transcript)|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:1TWG|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|refseq:NP_012243.3|dip:DIP-837N|mint:P16370 refseq:NP_014638.1|sgd:S000005365|ensemblfungi:YOL005C_mRNA(transcript)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR036603|interpro:IPR037685|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|ensemblfungi:YOL005C(gene)|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:4A93|rcsb pdb:5SVA|rcsb pdb:4BBR|rcsb pdb:5U5Q|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4V1M|rcsb pdb:6BLP|rcsb pdb:6UQ3|rcsb pdb:6BM2|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:7KEF|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|dip:DIP-937N|mint:P38902 psi-mi:"MI:0469"(intact) crc64:8E1D1E6BB7B51D89 crc64:A98D109C5FF8E356 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:JMIGnvEpr4Scb2i5tqjqSV2wvEw559292 rogid:C9ofD255l4o5MjuGiqUVPfY4FdQ559292 intact-crc:8DE0582FD1C53C68|rigid:OGE5L+EneQgjLifKQFIiDLidFUA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16370 uniprotkb:P08518 intact:EBI-15773|ensemblfungi:YIL021W|uniprotkb:D6VVQ8 intact:EBI-15767|uniprotkb:Q12738|uniprotkb:Q7Z9Y0|uniprotkb:D6W2K8|ensemblfungi:YOR151C psi-mi:rpb3_yeast(display_long)|uniprotkb:YIL021W(locus name)|uniprotkb:RPB3(gene name)|psi-mi:RPB3(display_short)|uniprotkb:DNA-directed RNA polymerase II 45 kDa polypeptide(gene name synonym)|uniprotkb:B44.5(gene name synonym) psi-mi:rpb2_yeast(display_long)|uniprotkb:YOR151C(locus name)|uniprotkb:RPB2(gene name)|psi-mi:RPB2(display_short)|uniprotkb:RPB150(gene name synonym)|uniprotkb:RPO22(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym)|uniprotkb:B150(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317452|imex:IM-14275-323 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001283|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3RZD|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:5C4A|rcsb pdb:7KEF|rcsb pdb:6UPY|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|rcsb pdb:6UPZ|reactome:R-SCE-674695|rcsb pdb:6UQ0|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|rcsb pdb:6UQ1|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|ensemblfungi:YIL021W(gene)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|ensemblfungi:YIL021W_mRNA(transcript)|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:1TWG|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|refseq:NP_012243.3|dip:DIP-837N|mint:P16370 sgd:S000005677|refseq:NP_014794.3|dip:DIP-14N|mint:P08518|ensemblfungi:YOR151C(gene)|ensemblfungi:YOR151C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) crc64:8E1D1E6BB7B51D89 crc64:BABD03212C0A583E figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:JMIGnvEpr4Scb2i5tqjqSV2wvEw559292 rogid:OtaUDREazRORKDcfBajDLPlXovY559292 intact-crc:5F2A6ACA498D8815|rigid:xIkfaw33soHUEzLrS46Q8iGlJnU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16467 uniprotkb:Q8TGU5 intact:EBI-5696|uniprotkb:D6VYC9|ensemblfungi:YLR134W intact:EBI-2042814|uniprotkb:D6VQU1|ensemblfungi:YBR296C-A psi-mi:pdc5_yeast(display_long)|uniprotkb:PDC5(gene name)|psi-mi:PDC5(display_short)|uniprotkb:Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase(gene name synonym)|uniprotkb:L3133(orf name)|uniprotkb:L9606.7(orf name)|uniprotkb:YLR134W(locus name) psi-mi:yb296_yeast(display_long)|uniprotkb:YBR296C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317474|imex:IM-14275-325 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013235.1|sgd:S000004124|dip:DIP-4603N|mint:P16467|ensemblfungi:YLR134W(gene)|ensemblfungi:YLR134W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000949"(aromatic amino acid family catabolic process to alcohol via Ehrlich pathway)|go:"GO:0004737"(pyruvate decarboxylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006559"(L-phenylalanine catabolic process)|go:"GO:0006569"(tryptophan catabolic process)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0016831"(carboxy-lyase activity)|go:"GO:0019655"(glycolytic fermentation to ethanol)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0047433"(branched-chain-2-oxoacid decarboxylase activity)|go:"GO:0047434"(indolepyruvate decarboxylase activity)|go:"GO:0050177"(phenylpyruvate decarboxylase activity)|interpro:IPR000399(TPP-binding enzymes, conserved site)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR012110(Pyruvate decarboxylase/indolepyruvate decarboxylase)|interpro:IPR029035|interpro:IPR029061 sgd:S000028605|refseq:NP_878055.3|mint:Q8TGU5|ensemblfungi:YBR296C-A(gene)|ensemblfungi:YBR296C-A_mRNA(transcript)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity) psi-mi:"MI:0469"(intact) crc64:DCA06A73E18DD819 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:QQ6QU3820/jVpa2PALg2x/cfjAI559292 rogid:DZubWD7lnwtea4Ne/bK1ITPFaJk559292 intact-crc:AACD340B13E71B12|rigid:j8rmuJrEf8h7XiG22m5+AeHCk0U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P16603 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-11940|ensemblfungi:YHR042W|uniprotkb:D3DKZ0 psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:ncpr_yeast(display_long)|uniprotkb:NCP1(gene name)|psi-mi:NCP1(display_short)|uniprotkb:NCPR1(gene name synonym)|uniprotkb:PRD1(gene name synonym)|uniprotkb:CPR1(gene name synonym)|uniprotkb:YHR042W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317485|imex:IM-14275-326 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 ensemblfungi:YHR042W(gene)|ensemblfungi:YHR042W_mRNA(transcript)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0003959"(NADPH dehydrogenase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0010181"(FMN binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0005739"(mitochondrion)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR023208|interpro:IPR039261|rcsb pdb:2BF4|rcsb pdb:2BN4|rcsb pdb:2BPO|rcsb pdb:3FJO|reactome:R-SCE-1222556|reactome:R-SCE-1474151|reactome:R-SCE-203615|reactome:R-SCE-392154|reactome:R-SCE-5218920|reactome:R-SCE-5578775|reactome:R-SCE-9009391|reactome:R-SCE-9033241|interpro:IPR029039|refseq:NP_011908.1|sgd:S000001084|mint:P16603|dip:DIP-8294N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:l8faixht4sd0KQhbt2DadH/8BPw559292 intact-crc:34105F1C8DF1542B|rigid:PwNLGPfglqjj5lSo8cJDggW8HRM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07786 uniprotkb:P16649 intact:EBI-33572|uniprotkb:D6VRB1|ensemblfungi:YDL246C intact:EBI-19654|uniprotkb:P17995|uniprotkb:P18323|uniprotkb:D6VR85|ensemblfungi:YCR084C psi-mi:dhso2_yeast(display_long)|uniprotkb:SOR2(gene name)|psi-mi:SOR2(display_short)|uniprotkb:Polyol dehydrogenase(gene name synonym)|uniprotkb:Xylitol dehydrogenase(gene name synonym)|uniprotkb:YDL246C(locus name) psi-mi:tup1_yeast(display_long)|uniprotkb:TUP1(gene name)|psi-mi:TUP1(display_short)|uniprotkb:AAR1(gene name synonym)|uniprotkb:AER2(gene name synonym)|uniprotkb:AMM1(gene name synonym)|uniprotkb:CYC9(gene name synonym)|uniprotkb:FLK1(gene name synonym)|uniprotkb:SFL2(gene name synonym)|uniprotkb:UMR7(gene name synonym)|uniprotkb:YCR084C(locus name)|uniprotkb:YCR84C(orf name)|uniprotkb:Glucose repression regulatory protein TUP1(gene name synonym)|uniprotkb:Flocculation suppressor protein(gene name synonym)|uniprotkb:Repressor AER2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317507|imex:IM-14275-328 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010035.1|sgd:S000002405|mint:Q07786|dip:DIP-1512N|ensemblfungi:YDL246C(gene)|ensemblfungi:YDL246C_mRNA(transcript)|go:"GO:0003939"(L-iditol 2-dehydrogenase activity)|go:"GO:0006062"(sorbitol catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019318"(hexose metabolic process)|go:"GO:0046526"(D-xylulose reductase activity)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR036291|reactome:R-SCE-5652227|reactome:R-SCE-5661270 refseq:NP_010007.1|sgd:S000000680|ensemblfungi:YCR084C(gene)|ensemblfungi:YCR084C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000433"(carbon catabolite repression of transcription from RNA polymerase II promoter by glucose)|go:"GO:0001198"(negative regulation of mating-type specific transcription from RNA polymerase II promoter)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060256"(regulation of flocculation)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:1900192"(positive regulation of single-species biofilm formation)|go:"GO:2000217"(regulation of invasive growth in response to glucose limitation)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR001680(WD40 repeat)|interpro:IPR013890(Transcriptional repressor Tup1, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:1ERJ|rcsb pdb:3VP8|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:3VP9|go:"GO:0016584"(nucleosome positioning)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043486"(histone exchange)|dip:DIP-512N|mint:P16649 psi-mi:"MI:0469"(intact) - crc64:444104AAD63CB944 figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YDaTXvu5wxiE+qUFqnUyaiYH4S4559292 rogid:luwCf4aC9uWc9C8Vt2etbCoLcU8559292 intact-crc:FF02721E1166EB80|rigid:xSpVaUdJBDVgWecKK5bGbCxg2G8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16649 uniprotkb:P14922 intact:EBI-19654|uniprotkb:P17995|uniprotkb:P18323|uniprotkb:D6VR85|ensemblfungi:YCR084C intact:EBI-18215|uniprotkb:D6VQB2|ensemblfungi:YBR112C psi-mi:tup1_yeast(display_long)|uniprotkb:TUP1(gene name)|psi-mi:TUP1(display_short)|uniprotkb:AAR1(gene name synonym)|uniprotkb:AER2(gene name synonym)|uniprotkb:AMM1(gene name synonym)|uniprotkb:CYC9(gene name synonym)|uniprotkb:FLK1(gene name synonym)|uniprotkb:SFL2(gene name synonym)|uniprotkb:UMR7(gene name synonym)|uniprotkb:YCR084C(locus name)|uniprotkb:YCR84C(orf name)|uniprotkb:Glucose repression regulatory protein TUP1(gene name synonym)|uniprotkb:Flocculation suppressor protein(gene name synonym)|uniprotkb:Repressor AER2(gene name synonym) psi-mi:cyc8_yeast(display_long)|uniprotkb:CYC8(gene name)|psi-mi:CYC8(display_short)|uniprotkb:CRT8(gene name synonym)|uniprotkb:YBR112C(locus name)|uniprotkb:YBR0908(orf name)|uniprotkb:SSN6(gene name synonym)|uniprotkb:Glucose repression mediator protein CYC8(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317496|imex:IM-14275-327 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010007.1|sgd:S000000680|ensemblfungi:YCR084C(gene)|ensemblfungi:YCR084C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000433"(carbon catabolite repression of transcription from RNA polymerase II promoter by glucose)|go:"GO:0001198"(negative regulation of mating-type specific transcription from RNA polymerase II promoter)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060256"(regulation of flocculation)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:1900192"(positive regulation of single-species biofilm formation)|go:"GO:2000217"(regulation of invasive growth in response to glucose limitation)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR001680(WD40 repeat)|interpro:IPR013890(Transcriptional repressor Tup1, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:1ERJ|rcsb pdb:3VP8|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:3VP9|go:"GO:0016584"(nucleosome positioning)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043486"(histone exchange)|dip:DIP-512N|mint:P16649 sgd:S000000316|ensemblfungi:YBR112C(gene)|ensemblfungi:YBR112C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1900191"(negative regulation of single-species biofilm formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0017053"(transcription repressor complex)|interpro:IPR001440(Tetratricopeptide TPR-1)|go:"GO:0031490"(chromatin DNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|reactome:R-SCE-2559580|go:"GO:0042826"(histone deacetylase binding)|reactome:R-SCE-3214842|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|refseq:NP_009670.3|dip:DIP-696N|mint:P14922 psi-mi:"MI:0469"(intact) crc64:444104AAD63CB944 crc64:FC2D0D0C1B181207 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:luwCf4aC9uWc9C8Vt2etbCoLcU8559292 rogid:gpjKszq6Hl6REDcJxD0NlI+WN/8559292 intact-crc:1C76E5B2F3C4DB2D|rigid:U+IAUnZoQMFI5dEq7lEl52gpCUk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17106 uniprotkb:P17106 intact:EBI-4096|uniprotkb:Q6Q5N1|uniprotkb:P17623|uniprotkb:D6VWN1|ensemblfungi:YJR060W intact:EBI-4096|uniprotkb:Q6Q5N1|uniprotkb:P17623|uniprotkb:D6VWN1|ensemblfungi:YJR060W psi-mi:cbf1_yeast(display_long)|uniprotkb:CEP1(gene name synonym)|uniprotkb:CP1(gene name synonym)|uniprotkb:CPF1(gene name synonym)|uniprotkb:J1730(orf name)|uniprotkb:YJR060W(locus name)|uniprotkb:CBF1(gene name)|psi-mi:CBF1(display_short)|uniprotkb:Centromere-binding factor 1(gene name synonym)|uniprotkb:Centromere promoter factor 1(gene name synonym) psi-mi:cbf1_yeast(display_long)|uniprotkb:CEP1(gene name synonym)|uniprotkb:CP1(gene name synonym)|uniprotkb:CPF1(gene name synonym)|uniprotkb:J1730(orf name)|uniprotkb:YJR060W(locus name)|uniprotkb:CBF1(gene name)|psi-mi:CBF1(display_short)|uniprotkb:Centromere-binding factor 1(gene name synonym)|uniprotkb:Centromere promoter factor 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317529|imex:IM-14275-330 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012594.1|sgd:S000003821|dip:DIP-2239N|mint:P17106|ensemblfungi:YJR060W(gene)|ensemblfungi:YJR060W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0089713"(Cbf1-Met4-Met28 complex)|go:"GO:0098781"(ncRNA transcription)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638 refseq:NP_012594.1|sgd:S000003821|dip:DIP-2239N|mint:P17106|ensemblfungi:YJR060W(gene)|ensemblfungi:YJR060W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0089713"(Cbf1-Met4-Met28 complex)|go:"GO:0098781"(ncRNA transcription)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SjrIzQ9f1rrxeycid/060/5MRY8559292 rogid:SjrIzQ9f1rrxeycid/060/5MRY8559292 intact-crc:5390E6C4D711FC08|rigid:d97uN/P9WUplrtc33d86FwZMaoE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:P17261 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-2058366|uniprotkb:D6VR77|ensemblfungi:YCR075C psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:ers1_yeast(display_long)|uniprotkb:ERS1(gene name)|psi-mi:ERS1(display_short)|uniprotkb:Transmembrane protein ERS1(gene name synonym)|uniprotkb:ERD suppressor(gene name synonym)|uniprotkb:YCR75C(orf name)|uniprotkb:YCR075C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317540|imex:IM-14275-331 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 refseq:NP_010000.1|sgd:S000000671|dip:DIP-8250N|mint:P17261|ensemblfungi:YCR075C(gene)|ensemblfungi:YCR075C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0015184"(L-cystine transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015811"(L-cystine transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR005282(Lysosomal cystine transporter)|interpro:IPR006603(Cystinosin/ERS1p repeat)|reactome:R-SCE-425393|reactome:R-SCE-5223345 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:ZJjRev6HMWAEavG0UCXkddzS3EY559292 intact-crc:20CF4B6BC12D86D9|rigid:IVKzpONd9Ds/Tl2crojXABPpTV4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17064 uniprotkb:P38264 intact:EBI-2047850|uniprotkb:D3DLV9|ensemblfungi:YER056C intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 psi-mi:fcy2_yeast(display_long)|uniprotkb:Cytosine/purine transport protein FCY2(gene name synonym)|uniprotkb:Fluorocytosine resistance protein 2(gene name synonym)|uniprotkb:YER056C(locus name)|uniprotkb:FCY2(gene name)|psi-mi:FCY2(display_short) psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317518|imex:IM-14275-329 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010976.1|sgd:S000000858|dip:DIP-7593N|mint:P17064|ensemblfungi:YER056C(gene)|ensemblfungi:YER056C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015205"(nucleobase transmembrane transporter activity)|go:"GO:0015212"(cytidine transmembrane transporter activity)|go:"GO:0015856"(cytosine transport)|go:"GO:0015861"(cytidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:0072530"(purine-containing compound transmembrane transport)|interpro:IPR001248(Permease for cytosine/purines, uracil, thiamine, allantoin)|interpro:IPR012681(Nucleobase cation symporter-1, NCS1)|interpro:IPR026030 refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:797s9w2xSSBhW0uTLcFEESToqgg559292 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 intact-crc:E560A5B16C2D5A4E|rigid:93oOlnrmCU5oPvyH4Ea20PmHORo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17555 uniprotkb:P11986 intact:EBI-4024|uniprotkb:D6W144|ensemblfungi:YNL138W intact:EBI-9257|ensemblfungi:YJL153C|uniprotkb:D6VW34 psi-mi:cap_yeast(display_long)|uniprotkb:SRV2(gene name)|psi-mi:SRV2(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:YNL138W(locus name)|uniprotkb:N1210(orf name)|uniprotkb:N1838(orf name) psi-mi:ino1_yeast(display_long)|uniprotkb:INO1(gene name)|psi-mi:INO1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym)|uniprotkb:J0610(orf name)|uniprotkb:YJL153C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317551|imex:IM-14275-332 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014261.1|sgd:S000005082|dip:DIP-77N|ensemblfungi:YNL138W(gene)|ensemblfungi:YNL138W_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007265"(Ras protein signal transduction)|mint:P17555|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0051014"(actin filament severing)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|rcsb pdb:1K4Z|rcsb pdb:1KQ5|reactome:R-SCE-6798695 rcsb pdb:1P1K|ensemblfungi:YJL153C(gene)|ensemblfungi:YJL153C_mRNA(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|rcsb pdb:1JKF|rcsb pdb:1JKI|rcsb pdb:1LA2|rcsb pdb:1P1F|rcsb pdb:1P1H|rcsb pdb:1P1I|rcsb pdb:1P1J|rcsb pdb:1RM0|reactome:R-SCE-1855183|refseq:NP_012382.2|sgd:S000003689|dip:DIP-5687N|mint:P11986 psi-mi:"MI:0469"(intact) crc64:0EB4D41205E2D464 crc64:282E2AE5D156289D figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3Fs9g+L5RnbkqYThVpOvSFrZoJ8559292 rogid:3OB3q28fOVxXSBMwMpLe2c1g8p8559292 intact-crc:3B8C3A731084A40C|rigid:eWOpo2CA+UJMW1HQvk1y8SX/7u4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13517 uniprotkb:P17555 intact:EBI-4013|uniprotkb:Q07082|uniprotkb:D6VVP8|ensemblfungi:YIL034C intact:EBI-4024|uniprotkb:D6W144|ensemblfungi:YNL138W psi-mi:capzb_yeast(display_long)|uniprotkb:YIL034C(locus name)|uniprotkb:CAP2(gene name)|psi-mi:CAP2(display_short) psi-mi:cap_yeast(display_long)|uniprotkb:SRV2(gene name)|psi-mi:SRV2(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:YNL138W(locus name)|uniprotkb:N1210(orf name)|uniprotkb:N1838(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317562|imex:IM-14275-333 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001296|refseq:NP_012230.3|dip:DIP-836N|ensemblfungi:YIL034C(gene)|ensemblfungi:YIL034C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030447"(filamentous growth)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|reactome:R-SCE-9013405|reactome:R-SCE-983231|mint:P13517 refseq:NP_014261.1|sgd:S000005082|dip:DIP-77N|ensemblfungi:YNL138W(gene)|ensemblfungi:YNL138W_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007265"(Ras protein signal transduction)|mint:P17555|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0051014"(actin filament severing)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|rcsb pdb:1K4Z|rcsb pdb:1KQ5|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) crc64:6E669023D1378778 crc64:0EB4D41205E2D464 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Kk8QoRXeJ3IU4tLcyHI5y7hDipk559292 rogid:3Fs9g+L5RnbkqYThVpOvSFrZoJ8559292 intact-crc:39D91BD58C9C9E44|rigid:vuBQMEQHiO8Y7FeB/KE+1mA/mTM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17555 uniprotkb:P17555 intact:EBI-4024|uniprotkb:D6W144|ensemblfungi:YNL138W intact:EBI-4024|uniprotkb:D6W144|ensemblfungi:YNL138W psi-mi:cap_yeast(display_long)|uniprotkb:SRV2(gene name)|psi-mi:SRV2(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:YNL138W(locus name)|uniprotkb:N1210(orf name)|uniprotkb:N1838(orf name) psi-mi:cap_yeast(display_long)|uniprotkb:SRV2(gene name)|psi-mi:SRV2(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:YNL138W(locus name)|uniprotkb:N1210(orf name)|uniprotkb:N1838(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317573|imex:IM-14275-334 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014261.1|sgd:S000005082|dip:DIP-77N|ensemblfungi:YNL138W(gene)|ensemblfungi:YNL138W_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007265"(Ras protein signal transduction)|mint:P17555|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0051014"(actin filament severing)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|rcsb pdb:1K4Z|rcsb pdb:1KQ5|reactome:R-SCE-6798695 refseq:NP_014261.1|sgd:S000005082|dip:DIP-77N|ensemblfungi:YNL138W(gene)|ensemblfungi:YNL138W_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007265"(Ras protein signal transduction)|mint:P17555|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0051014"(actin filament severing)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|rcsb pdb:1K4Z|rcsb pdb:1KQ5|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) crc64:0EB4D41205E2D464 crc64:0EB4D41205E2D464 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3Fs9g+L5RnbkqYThVpOvSFrZoJ8559292 rogid:3Fs9g+L5RnbkqYThVpOvSFrZoJ8559292 intact-crc:30675C60FAF76EDA|rigid:edak5VhGYueazP0zyyAgWsyGuAQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33204 uniprotkb:P17555 intact:EBI-2757|uniprotkb:D6VXS3|ensemblfungi:YKL013C intact:EBI-4024|uniprotkb:D6W144|ensemblfungi:YNL138W psi-mi:arpc4_yeast(display_long)|uniprotkb:ARC19(gene name)|psi-mi:ARC19(display_short)|uniprotkb:YKL013C(locus name)|uniprotkb:YKL166(orf name)|uniprotkb:Arp2/3 complex 20 kDa(gene name synonym) psi-mi:cap_yeast(display_long)|uniprotkb:SRV2(gene name)|psi-mi:SRV2(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:YNL138W(locus name)|uniprotkb:N1210(orf name)|uniprotkb:N1838(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317584|imex:IM-14275-335 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012912.1|sgd:S000001496|dip:DIP-1819N|mint:P33204|ensemblfungi:YKL013C(gene)|ensemblfungi:YKL013C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 refseq:NP_014261.1|sgd:S000005082|dip:DIP-77N|ensemblfungi:YNL138W(gene)|ensemblfungi:YNL138W_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007265"(Ras protein signal transduction)|mint:P17555|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0051014"(actin filament severing)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|rcsb pdb:1K4Z|rcsb pdb:1KQ5|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) crc64:B80CBD6642E39C1C crc64:0EB4D41205E2D464 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wscMsqBK/3Rsah+2vbE3REyYhhg559292 rogid:3Fs9g+L5RnbkqYThVpOvSFrZoJ8559292 intact-crc:AA6BAF920B1D62BF|rigid:NW3wJkRsq83zFpin/kAq9nNM4dM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17555 uniprotkb:P40518 intact:EBI-4024|uniprotkb:D6W144|ensemblfungi:YNL138W intact:EBI-2750|uniprotkb:D6VVM2|ensemblfungi:YIL062C psi-mi:cap_yeast(display_long)|uniprotkb:SRV2(gene name)|psi-mi:SRV2(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:YNL138W(locus name)|uniprotkb:N1210(orf name)|uniprotkb:N1838(orf name) psi-mi:arpc5_yeast(display_long)|uniprotkb:ARC15(gene name)|psi-mi:ARC15(display_short)|uniprotkb:Arp2/3 complex 16 kDa subunit(gene name synonym)|uniprotkb:YIL062C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317606|imex:IM-14275-337 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014261.1|sgd:S000005082|dip:DIP-77N|ensemblfungi:YNL138W(gene)|ensemblfungi:YNL138W_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007265"(Ras protein signal transduction)|mint:P17555|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0051014"(actin filament severing)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|rcsb pdb:1K4Z|rcsb pdb:1KQ5|reactome:R-SCE-6798695 refseq:NP_012202.1|sgd:S000001324|dip:DIP-2101N|mint:P40518|ensemblfungi:YIL062C(gene)|ensemblfungi:YIL062C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR036743|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-6798695|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:0EB4D41205E2D464 crc64:10E4DAF0F0801B02 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3Fs9g+L5RnbkqYThVpOvSFrZoJ8559292 rogid:iQ0mLisINMjXPulrRyDmrLcdpzU559292 intact-crc:D1E13249F18BBF44|rigid:vw49OQlRDxZvIGv4n+Gs8s7vALs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38328 uniprotkb:P17555 intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C intact:EBI-4024|uniprotkb:D6W144|ensemblfungi:YNL138W psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:cap_yeast(display_long)|uniprotkb:SRV2(gene name)|psi-mi:SRV2(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:YNL138W(locus name)|uniprotkb:N1210(orf name)|uniprotkb:N1838(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317595|imex:IM-14275-336 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 refseq:NP_014261.1|sgd:S000005082|dip:DIP-77N|ensemblfungi:YNL138W(gene)|ensemblfungi:YNL138W_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007265"(Ras protein signal transduction)|mint:P17555|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0051014"(actin filament severing)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|rcsb pdb:1K4Z|rcsb pdb:1KQ5|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) crc64:D75C6BB8EC35EEDF crc64:0EB4D41205E2D464 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 rogid:3Fs9g+L5RnbkqYThVpOvSFrZoJ8559292 intact-crc:89928E89F7477F42|rigid:uVf/ijnJH4++WRwJJweUFtDdamI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41811 uniprotkb:P17555 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W intact:EBI-4024|uniprotkb:D6W144|ensemblfungi:YNL138W psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:cap_yeast(display_long)|uniprotkb:SRV2(gene name)|psi-mi:SRV2(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:YNL138W(locus name)|uniprotkb:N1210(orf name)|uniprotkb:N1838(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317617|imex:IM-14275-338 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_014261.1|sgd:S000005082|dip:DIP-77N|ensemblfungi:YNL138W(gene)|ensemblfungi:YNL138W_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007265"(Ras protein signal transduction)|mint:P17555|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0051014"(actin filament severing)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|rcsb pdb:1K4Z|rcsb pdb:1KQ5|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) crc64:6A5E50BBEB02CB58 crc64:0EB4D41205E2D464 figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 rogid:3Fs9g+L5RnbkqYThVpOvSFrZoJ8559292 intact-crc:94B339843DE9A815|rigid:NjyCk7DkXFqF5MIA+mosjHzB1UY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17555 uniprotkb:P53250 intact:EBI-4024|uniprotkb:D6W144|ensemblfungi:YNL138W intact:EBI-19663|uniprotkb:D6VUL2|ensemblfungi:YGR080W psi-mi:cap_yeast(display_long)|uniprotkb:SRV2(gene name)|psi-mi:SRV2(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:YNL138W(locus name)|uniprotkb:N1210(orf name)|uniprotkb:N1838(orf name) psi-mi:twf1_yeast(display_long)|uniprotkb:TWF1(gene name)|psi-mi:TWF1(display_short)|uniprotkb:YGR080W(locus name)|uniprotkb:Twinfilin-A(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317628|imex:IM-14275-339 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014261.1|sgd:S000005082|dip:DIP-77N|ensemblfungi:YNL138W(gene)|ensemblfungi:YNL138W_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007265"(Ras protein signal transduction)|mint:P17555|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0051014"(actin filament severing)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|rcsb pdb:1K4Z|rcsb pdb:1KQ5|reactome:R-SCE-6798695 sgd:S000003312|ensemblfungi:YGR080W(gene)|ensemblfungi:YGR080W_mRNA(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0007015"(actin filament organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|refseq:NP_011594.3|dip:DIP-2202N|mint:P53250 psi-mi:"MI:0469"(intact) crc64:0EB4D41205E2D464 crc64:D9213BBB2D953DBD figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3Fs9g+L5RnbkqYThVpOvSFrZoJ8559292 rogid:dRJKUwolfd9OK7V77leZs+qODHc559292 intact-crc:A4CF5DCAE3E8041F|rigid:h6hkoHUW8tRGVVE+RDmgfFtoq1M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53731 uniprotkb:P17555 intact:EBI-2770|uniprotkb:D6W1L1|ensemblfungi:YNR035C intact:EBI-4024|uniprotkb:D6W144|ensemblfungi:YNL138W psi-mi:arpc2_yeast(display_long)|uniprotkb:ARC35(gene name)|psi-mi:ARC35(display_short)|uniprotkb:YNR035C(locus name)|uniprotkb:N3296(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym) psi-mi:cap_yeast(display_long)|uniprotkb:SRV2(gene name)|psi-mi:SRV2(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:YNL138W(locus name)|uniprotkb:N1210(orf name)|uniprotkb:N1838(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317639|imex:IM-14275-340 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014433.1|sgd:S000005318|dip:DIP-2304N|mint:P53731|ensemblfungi:YNR035C(gene)|ensemblfungi:YNR035C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072697"(protein localization to cell cortex)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 refseq:NP_014261.1|sgd:S000005082|dip:DIP-77N|ensemblfungi:YNL138W(gene)|ensemblfungi:YNL138W_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007265"(Ras protein signal transduction)|mint:P17555|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0051014"(actin filament severing)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|rcsb pdb:1K4Z|rcsb pdb:1KQ5|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) crc64:9AF71A93688729F6 crc64:0EB4D41205E2D464 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:URdgP2srz1O44fNGQh18L7bzC+c559292 rogid:3Fs9g+L5RnbkqYThVpOvSFrZoJ8559292 intact-crc:9EA3E18B357ED1AB|rigid:fyN5WuKkpYK92UwAK+jxi1mBTXc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17555 uniprotkb:Q05933 intact:EBI-4024|uniprotkb:D6W144|ensemblfungi:YNL138W intact:EBI-2764|uniprotkb:D6VZ07|ensemblfungi:YLR370C psi-mi:cap_yeast(display_long)|uniprotkb:SRV2(gene name)|psi-mi:SRV2(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:YNL138W(locus name)|uniprotkb:N1210(orf name)|uniprotkb:N1838(orf name) psi-mi:arpc3_yeast(display_long)|uniprotkb:ARC18(gene name)|psi-mi:ARC18(display_short)|uniprotkb:YLR370C(locus name)|uniprotkb:L8039.15(orf name)|uniprotkb:Arp2/3 complex 21 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317650|imex:IM-14275-341 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014261.1|sgd:S000005082|dip:DIP-77N|ensemblfungi:YNL138W(gene)|ensemblfungi:YNL138W_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007265"(Ras protein signal transduction)|mint:P17555|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0051014"(actin filament severing)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|rcsb pdb:1K4Z|rcsb pdb:1KQ5|reactome:R-SCE-6798695 sgd:S000004362|refseq:NP_013474.3|dip:DIP-2218N|mint:Q05933|ensemblfungi:YLR370C(gene)|ensemblfungi:YLR370C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR007204(ARP2/3 complex, 21 kDa p21-Arc subunit)|interpro:IPR036753|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:0EB4D41205E2D464 crc64:456EABC2B9CC4860 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3Fs9g+L5RnbkqYThVpOvSFrZoJ8559292 rogid:Fj4cwULcw1TK5uS1lJczcNc5gns559292 intact-crc:DCFF81F3FB4BD4F0|rigid:jmEe7M1+enneS1DMuLrw/WiG4wA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17555 uniprotkb:Q12324 intact:EBI-4024|uniprotkb:D6W144|ensemblfungi:YNL138W intact:EBI-33982|uniprotkb:Q08500|uniprotkb:Q7LGN3|uniprotkb:D6W2E9|ensemblfungi:YOR087W psi-mi:cap_yeast(display_long)|uniprotkb:SRV2(gene name)|psi-mi:SRV2(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:YNL138W(locus name)|uniprotkb:N1210(orf name)|uniprotkb:N1838(orf name) psi-mi:yvc1_yeast(display_long)|uniprotkb:YOR088W(orf name)|uniprotkb:YOR087W(locus name)|uniprotkb:YVC1(gene name)|psi-mi:YVC1(display_short)|uniprotkb:YOR3151W(orf name)|uniprotkb:Yeast vacuolar conductance protein 1(gene name synonym)|uniprotkb:TRP homolog(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317661|imex:IM-14275-342 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014261.1|sgd:S000005082|dip:DIP-77N|ensemblfungi:YNL138W(gene)|ensemblfungi:YNL138W_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007265"(Ras protein signal transduction)|mint:P17555|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0051014"(actin filament severing)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|rcsb pdb:1K4Z|rcsb pdb:1KQ5|reactome:R-SCE-6798695 refseq:NP_014730.2|sgd:S000005613|mint:Q12324|dip:DIP-4157N|ensemblfungi:YOR087W(gene)|ensemblfungi:YOR087W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005216"(ion channel activity)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005272"(sodium channel activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:1990816"(vacuole-mitochondrion membrane contact site)|interpro:IPR024862|rcsb pdb:6WHG|reactome:R-SCE-3295583 psi-mi:"MI:0469"(intact) crc64:0EB4D41205E2D464 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3Fs9g+L5RnbkqYThVpOvSFrZoJ8559292 rogid:9sMQkLwyXeGTJchkiADQckbQZZI559292 intact-crc:F874427F1B562695|rigid:GaO7LwlJjixhK4GxddJcMRMIrEQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17883 uniprotkb:P17883 intact:EBI-1861|uniprotkb:Q06585|ensemblfungi:YPR189W intact:EBI-1861|uniprotkb:Q06585|ensemblfungi:YPR189W psi-mi:ski3_yeast(display_long)|uniprotkb:SKI3(gene name)|psi-mi:SKI3(display_short)|uniprotkb:P9677.7(orf name)|uniprotkb:YPR189W(locus name) psi-mi:ski3_yeast(display_long)|uniprotkb:SKI3(gene name)|psi-mi:SKI3(display_short)|uniprotkb:P9677.7(orf name)|uniprotkb:YPR189W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317672|imex:IM-14275-343 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006393|refseq:NP_015515.1|dip:DIP-6379N|mint:P17883|ensemblfungi:YPR189W(gene)|ensemblfungi:YPR189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039226|interpro:IPR040962|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958 sgd:S000006393|refseq:NP_015515.1|dip:DIP-6379N|mint:P17883|ensemblfungi:YPR189W(gene)|ensemblfungi:YPR189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039226|interpro:IPR040962|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958 psi-mi:"MI:0469"(intact) crc64:18FFF78D7CA5A6E4 crc64:18FFF78D7CA5A6E4 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wjMKcbtN38crXFX7hQgZ0Bz475Y559292 rogid:wjMKcbtN38crXFX7hQgZ0Bz475Y559292 intact-crc:0A77C2446B591096|rigid:46khcBrY1yP0nLGxzy0cd4aWxEo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17898 uniprotkb:P10614 intact:EBI-2050738|uniprotkb:D6W152|ensemblfungi:YNL130C intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:cpt1_yeast(display_long)|uniprotkb:Diacylglycerol cholinephosphotransferase 1(gene name synonym)|uniprotkb:Sn-1,2-diacylglycerol cholinephosphotransferase(gene name synonym)|uniprotkb:N1218(orf name)|uniprotkb:N1867(orf name)|uniprotkb:YNL130C(locus name)|uniprotkb:CPT1(gene name)|psi-mi:CPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase CPT1(gene name synonym) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317694|imex:IM-14275-345 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005074|refseq:NP_014269.4|dip:DIP-7848N|mint:P17898|ensemblfungi:YNL130C(gene)|ensemblfungi:YNL130C_mRNA(transcript)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006657"(CDP-choline pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213 refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:PsU8UELFPsbtbzOS6oBnXJAuk/A559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:E463071401ABC763|rigid:b72IlPKwv5/mFyjVY7IXG63ChFo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6Q5K6 uniprotkb:P17883 intact:EBI-392766|ensemblfungi:YML058W-A|uniprotkb:D6VZB5 intact:EBI-1861|uniprotkb:Q06585|ensemblfungi:YPR189W psi-mi:hug1_yeast(display_long)|uniprotkb:HUG1(gene name)|psi-mi:HUG1(display_short)|uniprotkb:YML058W-A(locus name) psi-mi:ski3_yeast(display_long)|uniprotkb:SKI3(gene name)|psi-mi:SKI3(display_short)|uniprotkb:P9677.7(orf name)|uniprotkb:YPR189W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317683|imex:IM-14275-344 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML058W-A(gene)|ensemblfungi:YML058W-A_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:1905117"(regulation of ribonucleoside-diphosphate reductase activity)|go:"GO:1990846"(ribonucleoside-diphosphate reductase inhibitor activity)|sgd:S000007472|refseq:NP_219498.1|mint:Q6Q5K6 sgd:S000006393|refseq:NP_015515.1|dip:DIP-6379N|mint:P17883|ensemblfungi:YPR189W(gene)|ensemblfungi:YPR189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039226|interpro:IPR040962|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958 psi-mi:"MI:0469"(intact) - crc64:18FFF78D7CA5A6E4 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:x+quBrnP+8yql7JGQ1NK4j5ubbw559292 rogid:wjMKcbtN38crXFX7hQgZ0Bz475Y559292 intact-crc:DA0941FF3D3C31DC|rigid:EvJ/Mk6iCrD7kdo8yUoRNA7/1/E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17898 uniprotkb:P17898 intact:EBI-2050738|uniprotkb:D6W152|ensemblfungi:YNL130C intact:EBI-2050738|uniprotkb:D6W152|ensemblfungi:YNL130C psi-mi:cpt1_yeast(display_long)|uniprotkb:Diacylglycerol cholinephosphotransferase 1(gene name synonym)|uniprotkb:Sn-1,2-diacylglycerol cholinephosphotransferase(gene name synonym)|uniprotkb:N1218(orf name)|uniprotkb:N1867(orf name)|uniprotkb:YNL130C(locus name)|uniprotkb:CPT1(gene name)|psi-mi:CPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase CPT1(gene name synonym) psi-mi:cpt1_yeast(display_long)|uniprotkb:Diacylglycerol cholinephosphotransferase 1(gene name synonym)|uniprotkb:Sn-1,2-diacylglycerol cholinephosphotransferase(gene name synonym)|uniprotkb:N1218(orf name)|uniprotkb:N1867(orf name)|uniprotkb:YNL130C(locus name)|uniprotkb:CPT1(gene name)|psi-mi:CPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase CPT1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317705|imex:IM-14275-346 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005074|refseq:NP_014269.4|dip:DIP-7848N|mint:P17898|ensemblfungi:YNL130C(gene)|ensemblfungi:YNL130C_mRNA(transcript)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006657"(CDP-choline pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213 sgd:S000005074|refseq:NP_014269.4|dip:DIP-7848N|mint:P17898|ensemblfungi:YNL130C(gene)|ensemblfungi:YNL130C_mRNA(transcript)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006657"(CDP-choline pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:PsU8UELFPsbtbzOS6oBnXJAuk/A559292 rogid:PsU8UELFPsbtbzOS6oBnXJAuk/A559292 intact-crc:E24A3F3C2439E7DC|rigid:PVITRZUtPzOoP/YVCeldwvBWxoc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17898 uniprotkb:P22140 intact:EBI-2050738|uniprotkb:D6W152|ensemblfungi:YNL130C intact:EBI-6494|uniprotkb:D3DL73|ensemblfungi:YHR123W psi-mi:cpt1_yeast(display_long)|uniprotkb:Diacylglycerol cholinephosphotransferase 1(gene name synonym)|uniprotkb:Sn-1,2-diacylglycerol cholinephosphotransferase(gene name synonym)|uniprotkb:N1218(orf name)|uniprotkb:N1867(orf name)|uniprotkb:YNL130C(locus name)|uniprotkb:CPT1(gene name)|psi-mi:CPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase CPT1(gene name synonym) psi-mi:ept1_yeast(display_long)|uniprotkb:EPT1(gene name)|psi-mi:EPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase EPT1(gene name synonym)|uniprotkb:YHR123W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317716|imex:IM-14275-347 author score:88.11 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005074|refseq:NP_014269.4|dip:DIP-7848N|mint:P17898|ensemblfungi:YNL130C(gene)|ensemblfungi:YNL130C_mRNA(transcript)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006657"(CDP-choline pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213 refseq:NP_011991.1|sgd:S000001165|mint:P22140|dip:DIP-5619N|ensemblfungi:YHR123W(gene)|ensemblfungi:YHR123W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0004307"(ethanolaminephosphotransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213|interpro:IPR014472(Choline/ethanolaminephosphotransferase) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:88.11|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:PsU8UELFPsbtbzOS6oBnXJAuk/A559292 rogid:CWeN5fKw1tHLle/Vgn+jmL/zrQk559292 intact-crc:67F635606A4C8B20|rigid:cfvCSbgRZoDpyqKmb4ZXoIbaCsc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17898 uniprotkb:P26570 intact:EBI-2050738|uniprotkb:D6W152|ensemblfungi:YNL130C intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 psi-mi:cpt1_yeast(display_long)|uniprotkb:Diacylglycerol cholinephosphotransferase 1(gene name synonym)|uniprotkb:Sn-1,2-diacylglycerol cholinephosphotransferase(gene name synonym)|uniprotkb:N1218(orf name)|uniprotkb:N1867(orf name)|uniprotkb:YNL130C(locus name)|uniprotkb:CPT1(gene name)|psi-mi:CPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase CPT1(gene name synonym) psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317727|imex:IM-14275-348 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005074|refseq:NP_014269.4|dip:DIP-7848N|mint:P17898|ensemblfungi:YNL130C(gene)|ensemblfungi:YNL130C_mRNA(transcript)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006657"(CDP-choline pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213 ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N psi-mi:"MI:0469"(intact) - crc64:8B7F009521F72C15 figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:PsU8UELFPsbtbzOS6oBnXJAuk/A559292 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 intact-crc:17AB6737C9272884|rigid:+SsqE86/zfItwY02GTLxiUQ1nMY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17898 uniprotkb:P54837 intact:EBI-2050738|uniprotkb:D6W152|ensemblfungi:YNL130C intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:cpt1_yeast(display_long)|uniprotkb:Diacylglycerol cholinephosphotransferase 1(gene name synonym)|uniprotkb:Sn-1,2-diacylglycerol cholinephosphotransferase(gene name synonym)|uniprotkb:N1218(orf name)|uniprotkb:N1867(orf name)|uniprotkb:YNL130C(locus name)|uniprotkb:CPT1(gene name)|psi-mi:CPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase CPT1(gene name synonym) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317738|imex:IM-14275-349 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005074|refseq:NP_014269.4|dip:DIP-7848N|mint:P17898|ensemblfungi:YNL130C(gene)|ensemblfungi:YNL130C_mRNA(transcript)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006657"(CDP-choline pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:PsU8UELFPsbtbzOS6oBnXJAuk/A559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:6E90E3153ACB826D|rigid:8oJTduuy+iT3HLZl+BM6rWnzYTA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17898 uniprotkb:Q12270 intact:EBI-2050738|uniprotkb:D6W152|ensemblfungi:YNL130C intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:cpt1_yeast(display_long)|uniprotkb:Diacylglycerol cholinephosphotransferase 1(gene name synonym)|uniprotkb:Sn-1,2-diacylglycerol cholinephosphotransferase(gene name synonym)|uniprotkb:N1218(orf name)|uniprotkb:N1867(orf name)|uniprotkb:YNL130C(locus name)|uniprotkb:CPT1(gene name)|psi-mi:CPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase CPT1(gene name synonym) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317760|imex:IM-14275-351 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005074|refseq:NP_014269.4|dip:DIP-7848N|mint:P17898|ensemblfungi:YNL130C(gene)|ensemblfungi:YNL130C_mRNA(transcript)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006657"(CDP-choline pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213 refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:PsU8UELFPsbtbzOS6oBnXJAuk/A559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:1445814AAD6DEDBF|rigid:LTMc2U+m1B1P5TcUyRWu53qQMDs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:P17898 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-2050738|uniprotkb:D6W152|ensemblfungi:YNL130C psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:cpt1_yeast(display_long)|uniprotkb:Diacylglycerol cholinephosphotransferase 1(gene name synonym)|uniprotkb:Sn-1,2-diacylglycerol cholinephosphotransferase(gene name synonym)|uniprotkb:N1218(orf name)|uniprotkb:N1867(orf name)|uniprotkb:YNL130C(locus name)|uniprotkb:CPT1(gene name)|psi-mi:CPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase CPT1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317749|imex:IM-14275-350 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 sgd:S000005074|refseq:NP_014269.4|dip:DIP-7848N|mint:P17898|ensemblfungi:YNL130C(gene)|ensemblfungi:YNL130C_mRNA(transcript)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006657"(CDP-choline pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:PsU8UELFPsbtbzOS6oBnXJAuk/A559292 intact-crc:740E85ED90DE75DB|rigid:oGaSw9K9omT3MOgn64Kb7vkxStk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P18410 uniprotkb:Q02772 intact:EBI-17857|uniprotkb:D6VPK9|ensemblfungi:YAL009W intact:EBI-14134|ensemblfungi:YJR034W|uniprotkb:D6VWK7 psi-mi:spo7_yeast(display_long)|uniprotkb:SPO7(gene name)|psi-mi:SPO7(display_short)|uniprotkb:YAL009W(locus name) psi-mi:pt191_yeast(display_long)|uniprotkb:PET191(gene name)|psi-mi:PET191(display_short)|uniprotkb:J1604(orf name)|uniprotkb:YJR034W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317771|imex:IM-14275-352 author score:99.36 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009393.1|sgd:S000000007|ensemblfungi:YAL009W(gene)|ensemblfungi:YAL009W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061709"(reticulophagy)|go:"GO:0071071"(regulation of phospholipid biosynthetic process)|go:"GO:0071072"(negative regulation of phospholipid biosynthetic process)|go:"GO:0071595"(Nem1-Spo7 phosphatase complex)|go:"GO:1903740"(positive regulation of phosphatidate phosphatase activity)|interpro:IPR005605(Sporulation/nuclear morphology, Spo7)|dip:DIP-2441N|mint:P18410 ensemblfungi:YJR034W(gene)|ensemblfungi:YJR034W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR018793|refseq:NP_012568.1|sgd:S000003795|mint:Q02772|dip:DIP-1619N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.36|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:B7j7WWFyirigaa44+wgwLMNrPlM559292 rogid:Y2xXA5HsKzl3I4/DuFs5+mLaJUo559292 intact-crc:8908D0D05092C234|rigid:pYhqKZ8hfc879LRvKg0/XLWchn0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23202 uniprotkb:P18494 intact:EBI-20138|uniprotkb:D6W0W3|ensemblfungi:YNL229C intact:EBI-7657|uniprotkb:D3DLU0|ensemblfungi:YER040W psi-mi:ure2_yeast(display_long)|uniprotkb:URE2(gene name)|psi-mi:URE2(display_short)|uniprotkb:Disulfide reductase(gene name synonym)|uniprotkb:Glutathione peroxidase(gene name synonym)|uniprotkb:N1165(orf name)|uniprotkb:YNL229C(locus name) psi-mi:gln3_yeast(display_long)|uniprotkb:YER040W(locus name)|uniprotkb:GLN3(gene name)|psi-mi:GLN3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317782|imex:IM-14275-353 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014170.1|sgd:S000005173|ensemblfungi:YNL229C(gene)|ensemblfungi:YNL229C_mRNA(transcript)|mint:P23202|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0010044"(response to aluminum ion)|go:"GO:0032447"(protein urmylation)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR017298(Prion URE2)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:1G6W|rcsb pdb:1G6Y|rcsb pdb:1HQO|rcsb pdb:1JZR|rcsb pdb:1K0A|rcsb pdb:1K0B|rcsb pdb:1K0C|rcsb pdb:1K0D|go:"GO:0003714"(transcription corepressor activity)|dip:DIP-1308N sgd:S000000842|refseq:NP_010958.3|mint:P18494|dip:DIP-2353N|ensemblfungi:YER040W(gene)|ensemblfungi:YER040W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001080"(nitrogen catabolite activation of transcription from RNA polymerase II promoter)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0036278"(positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:2001159"(regulation of protein localization by the Cvt pathway)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) crc64:2C628976034B0F1C crc64:3159E1844469942E figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jjsWygBsEp8axNurMa3pxPMQJ2k559292 rogid:t3jui1KcKYLFSc0QGwRGq6uPl9Y559292 intact-crc:8D79CEEC02FE9922|rigid:W/4H+epvocbDyEkcbMPm608I/wk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P18759 uniprotkb:P41811 intact:EBI-16565|uniprotkb:Q07067|ensemblfungi:YBR080C|uniprotkb:D6VQ79 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:sec18_yeast(display_long)|uniprotkb:SEC18(gene name)|psi-mi:SEC18(display_short)|uniprotkb:YBR0736(orf name)|uniprotkb:YBR080C(locus name) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317793|imex:IM-14275-354 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009636.3|sgd:S000000284|ensemblfungi:YBR080C(gene)|ensemblfungi:YBR080C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000149"(SNARE binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043332"(mating projection tip)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0048219"(inter-Golgi cisterna vesicle-mediated transport)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0070300"(phosphatidic acid binding)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|rcsb pdb:1CR5|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438|reactome:R-SCE-6811440|reactome:R-SCE-204005|dip:DIP-2497N|mint:P18759 refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:AD6CE77EA3674B3C crc64:6A5E50BBEB02CB58 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZJ91vB4kwILooUNKu56bAggaIAk559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:5B60D88C227A4B27|rigid:LcLVrwENskEV3s1zNc9KsdwjjTo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19454 uniprotkb:P38930 intact:EBI-9548|ensemblfungi:YOR061W|uniprotkb:D6W2C4 intact:EBI-9578|ensemblfungi:YOR039W|uniprotkb:D6W2A6 psi-mi:csk22_yeast(display_long)|uniprotkb:CKA2(gene name)|psi-mi:CKA2(display_short)|uniprotkb:YOR29-12(orf name)|uniprotkb:YOR061W(locus name) psi-mi:csk2c_yeast(display_long)|uniprotkb:CKB2(gene name)|psi-mi:CKB2(display_short)|uniprotkb:OR26.32(orf name)|uniprotkb:YOR039W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317815|imex:IM-14275-356 author score:98.11 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR061W(gene)|ensemblfungi:YOR061W_mRNA(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007535"(donor selection)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0034456"(UTP-C complex)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-2514853|reactome:R-SCE-6804756|reactome:R-SCE-8934903|reactome:R-SCE-8948751|refseq:NP_014704.1|sgd:S000005587|mint:P19454|dip:DIP-1038N ensemblfungi:YOR039W(gene)|ensemblfungi:YOR039W_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0032545"(CURI complex)|go:"GO:0034456"(UTP-C complex)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|reactome:R-SCE-2514853|reactome:R-SCE-6798695|reactome:R-SCE-6804756|reactome:R-SCE-8934903|reactome:R-SCE-8948751|refseq:NP_014682.1|sgd:S000005565|mint:P38930|dip:DIP-262N psi-mi:"MI:0469"(intact) crc64:30E214BD852824D0 crc64:D6060CB3D70B19A4 figure legend:tables S3 and S4|author-confidence:98.11|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:E39eioYivVEqVSUhL99a2iGvisg559292 rogid:X+0JSYVQigL0wSbWYCkorc8jqpw559292 intact-crc:1D32E4F30D7006AE|rigid:qIOUgiWwfVanMOVztJlwK2hpVBA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42944 uniprotkb:P19158 intact:EBI-8042|uniprotkb:D6VW74|ensemblfungi:YJL110C intact:EBI-9354|uniprotkb:O13592|ensemblfungi:YOL081W|uniprotkb:Q08239|uniprotkb:D6W1Y7 psi-mi:gzf3_yeast(display_long)|uniprotkb:GZF3(gene name)|psi-mi:GZF3(display_short)|uniprotkb:J0806(orf name)|uniprotkb:YJL110C(locus name) psi-mi:ira2_yeast(display_long)|uniprotkb:IRA2(gene name)|psi-mi:IRA2(display_short)|uniprotkb:CCS1(gene name synonym)|uniprotkb:GLC4(gene name synonym)|uniprotkb:YOL081W(locus name)|uniprotkb:O0985(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317804|imex:IM-14275-355 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012425.1|sgd:S000003646|mint:P42944|dip:DIP-1359N|ensemblfungi:YJL110C(gene)|ensemblfungi:YJL110C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355|reactome:R-SCE-9018519 ensemblfungi:YOL081W(gene)|ensemblfungi:YOL081W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070417"(cellular response to cold)|go:"GO:0071248"(cellular response to metal ion)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR036865|interpro:IPR039360|reactome:R-SCE-9696273|refseq:NP_014560.1|sgd:S000005441|dip:DIP-6376N|mint:P19158 psi-mi:"MI:0469"(intact) crc64:807243799BFAB704 crc64:C14B5396D6FB9B5C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HOMBFcxVuABRuzPHcnDG87+R6sQ559292 rogid:JdDdmOtwEIYeakOi0APLo5HOLxs559292 intact-crc:3B11A72953B41577|rigid:qsZZ5HLP8dj0FsFvrLSJ287evCQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19524 uniprotkb:P19524 intact:EBI-11659|ensemblfungi:YOR326W|uniprotkb:D6W323 intact:EBI-11659|ensemblfungi:YOR326W|uniprotkb:D6W323 psi-mi:myo2_yeast(display_long)|uniprotkb:MYO2(gene name)|psi-mi:MYO2(display_short)|uniprotkb:CDC66(gene name synonym)|uniprotkb:YOR326W(locus name)|uniprotkb:O6167(orf name)|uniprotkb:Class V unconventional myosin MYO2(gene name synonym)|uniprotkb:Type V myosin heavy chain MYO2(gene name synonym)|uniprotkb:Cell division control protein 66(gene name synonym) psi-mi:myo2_yeast(display_long)|uniprotkb:MYO2(gene name)|psi-mi:MYO2(display_short)|uniprotkb:CDC66(gene name synonym)|uniprotkb:YOR326W(locus name)|uniprotkb:O6167(orf name)|uniprotkb:Class V unconventional myosin MYO2(gene name synonym)|uniprotkb:Type V myosin heavy chain MYO2(gene name synonym)|uniprotkb:Cell division control protein 66(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317826|imex:IM-14275-357 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR326W(gene)|ensemblfungi:YOR326W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007107"(membrane addition at site of cytokinesis)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0009826"(unidimensional cell growth)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030133"(transport vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0043332"(mating projection tip)|go:"GO:0045033"(peroxisome inheritance)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0051015"(actin filament binding)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002710(Dilute)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|go:"GO:0031941"(filamentous actin)|interpro:IPR036103|interpro:IPR036961|rcsb pdb:1M45|rcsb pdb:1M46|rcsb pdb:1N2D|rcsb pdb:2F6H|rcsb pdb:6EYW|rcsb pdb:6IXO|rcsb pdb:6IXQ|rcsb pdb:6IXR|reactome:R-SCE-190873|reactome:R-SCE-9013419|reactome:R-SCE-9013425|rcsb pdb:6IXP|refseq:NP_014971.1|sgd:S000005853|mint:P19524|dip:DIP-2308N ensemblfungi:YOR326W(gene)|ensemblfungi:YOR326W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007107"(membrane addition at site of cytokinesis)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0009826"(unidimensional cell growth)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030133"(transport vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0043332"(mating projection tip)|go:"GO:0045033"(peroxisome inheritance)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0051015"(actin filament binding)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002710(Dilute)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|go:"GO:0031941"(filamentous actin)|interpro:IPR036103|interpro:IPR036961|rcsb pdb:1M45|rcsb pdb:1M46|rcsb pdb:1N2D|rcsb pdb:2F6H|rcsb pdb:6EYW|rcsb pdb:6IXO|rcsb pdb:6IXQ|rcsb pdb:6IXR|reactome:R-SCE-190873|reactome:R-SCE-9013419|reactome:R-SCE-9013425|rcsb pdb:6IXP|refseq:NP_014971.1|sgd:S000005853|mint:P19524|dip:DIP-2308N psi-mi:"MI:0469"(intact) crc64:1F7E2887C1E59D54 crc64:1F7E2887C1E59D54 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:j44waBLI7ZT0FSaaVcWg6SIQuB4559292 rogid:j44waBLI7ZT0FSaaVcWg6SIQuB4559292 intact-crc:9BEF0D01D1D2D209|rigid:1X2ABjNDJQNpSIDmGnRN/FvY52Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19736 uniprotkb:P32801 intact:EBI-511|ensemblfungi:YDL030W|uniprotkb:D6VRW2 intact:EBI-6400|uniprotkb:D6VXN9|ensemblfungi:YKL048C psi-mi:prp9_yeast(display_long)|uniprotkb:PRP9(gene name)|psi-mi:PRP9(display_short)|uniprotkb:D2773(orf name)|uniprotkb:YDL030W(locus name) psi-mi:elm1_yeast(display_long)|uniprotkb:ELM1(gene name)|psi-mi:ELM1(display_short)|uniprotkb:YKL261(orf name)|uniprotkb:YKL048C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317837|imex:IM-14275-358 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDL030W(gene)|ensemblfungi:YDL030W_mRNA(transcript)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022755|interpro:IPR024598|interpro:IPR031590|interpro:IPR031774|interpro:IPR031776|interpro:IPR036236|refseq:NP_010254.1|sgd:S000002188|rcsb pdb:4DGW|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6G90|dip:DIP-651N|mint:P19736 refseq:NP_012876.1|sgd:S000001531|mint:P32801|dip:DIP-2731N|ensemblfungi:YKL048C(gene)|ensemblfungi:YKL048C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000921"(septin ring assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042493"|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902935"(protein localization to septin ring)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like) psi-mi:"MI:0469"(intact) crc64:9020885E620488F3 crc64:33C3A7E188DF12C4 figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:gdiY5/Azr3xdR4IiaMsyAcxJyXA559292 rogid:1D4gReYA4n2fikL36mu5dOdbWIQ559292 intact-crc:3EC8442A9B62FED7|rigid:TyyWqkX89sh941IhgBHBbLxyMn8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10823 uniprotkb:P19807 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317848|imex:IM-14275-359 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) crc64:881B91792AE91748 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:97E43DA6A1383A8A|rigid:+2t39dgCRTjAeE84tJ29AiWEfsA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23585 uniprotkb:P19807 intact:EBI-2054100|uniprotkb:D6VZI5|ensemblfungi:YMR011W intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:hxt2_yeast(display_long)|uniprotkb:YM8270.15(orf name)|uniprotkb:YMR011W(locus name)|uniprotkb:HXT2(gene name)|psi-mi:HXT2(display_short) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317870|imex:IM-14275-361 author score:99.32 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013724.1|sgd:S000004613|dip:DIP-7912N|mint:P23585|ensemblfungi:YMR011W(gene)|ensemblfungi:YMR011W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.32|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:d4PFyh6BHnB/WnnF3A4GF3EphgY559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:C348DA041D055EB8|rigid:6iPXAtmzsPetahKrGUUcMw0wyyk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:P19807 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317859|imex:IM-14275-360 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:3EEE53E543C9BD6A|rigid:gX50SHsTJAXq7caK1dk4PhWoRZ8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:P19807 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317892|imex:IM-14275-363 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) crc64:8B7F009521F72C15 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:CF376C2331D1A864|rigid:xQfSbc+Zj57Ia3BEzgFURoyv3PA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:P25619 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317881|imex:IM-14275-362 author score:96.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) - crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:96.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:BBB76C5530BC3920|rigid:GEzS5hrz+q+8qXF2FpnPAa/beZY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30605 uniprotkb:P19807 intact:EBI-2050956|uniprotkb:D6VTB9|ensemblfungi:YDR497C intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:itr1_yeast(display_long)|uniprotkb:D9719.3(orf name)|uniprotkb:YDR497C(locus name)|uniprotkb:ITR1(gene name)|psi-mi:ITR1(display_short) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317914|imex:IM-14275-365 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010785.1|sgd:S000002905|dip:DIP-7406N|mint:P30605|ensemblfungi:YDR497C(gene)|ensemblfungi:YDR497C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GgtK4YFe7ZCZcmVpV5q1KY2F0Ds559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:896BDCF7A5E4F31E|rigid:LiFeioVsHdXRbWMROLmlCQPyCRA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28321 uniprotkb:P19807 intact:EBI-26790|uniprotkb:D6VXJ4|ensemblfungi:YKL094W intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:mgll_yeast(display_long)|uniprotkb:YJU3(gene name)|psi-mi:YJU3(display_short)|uniprotkb:Monoacylglycerol hydrolase(gene name synonym)|uniprotkb:Monoacylglycerol lipase(gene name synonym)|uniprotkb:Serine hydrolase YJU3(gene name synonym)|uniprotkb:YKL441(orf name)|uniprotkb:YKL094W(locus name)|uniprotkb:Fatty acid ethyl ester hydrolase(gene name synonym) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317903|imex:IM-14275-364 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022742|refseq:NP_012829.1|sgd:S000001577|mint:P28321|interpro:IPR029058|ensemblfungi:YKL094W(gene)|ensemblfungi:YKL094W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0071944"(cell periphery)|rcsb pdb:4ZWN|rcsb pdb:4ZXF refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IHpY1aez3MG+bn7bThCBdvE6KMw559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:2B319458CE20EADD|rigid:WhWDmG25y/fX78grsfOwbjnPkaA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:P32465 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317925|imex:IM-14275-366 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 intact-crc:6F7657001562CD78|rigid:op4fO/WvIbO0yPsUNcx2hY+2iaE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33302 uniprotkb:P19807 intact:EBI-13038|uniprotkb:D6W2L0|ensemblfungi:YOR153W intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:pdr5_yeast(display_long)|uniprotkb:PDR5(gene name)|psi-mi:PDR5(display_short)|uniprotkb:LEM1(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 5(gene name synonym)|uniprotkb:Suppressor of toxicity of sporidesmin(gene name synonym)|uniprotkb:YOR153W(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317936|imex:IM-14275-367 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005679|refseq:NP_014796.3|mint:P33302|dip:DIP-6776N|ensemblfungi:YOR153W(gene)|ensemblfungi:YOR153W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR029481|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sd6SJWf6B0rDZnLVaPHyvr4lhew559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:15913FB8B08AB0FB|rigid:x/fiPppPYeAK+QWN3PtpxeH0D1Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:P33413 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-2060312|uniprotkb:D3DKP5|ensemblfungi:YHL016C psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:dur3_yeast(display_long)|uniprotkb:DUR3(gene name)|psi-mi:DUR3(display_short)|uniprotkb:YHL016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317947|imex:IM-14275-368 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) interpro:IPR031155|refseq:NP_011847.1|sgd:S000001008|interpro:IPR001734(Na+/solute symporter)|interpro:IPR038377|mint:P33413|ensemblfungi:YHL016C(gene)|ensemblfungi:YHL016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0015204"(urea transmembrane transporter activity)|go:"GO:0015489"(putrescine transmembrane transporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015840"(urea transport)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:oTFsdtOngA3q5wCbhK/fpVlIsz0559292 intact-crc:37C113BA82A9E33C|rigid:Suu3cE+ERRMX02xT7drky9+iZAU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:P19807 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317969|imex:IM-14275-370 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:76C29EFA0EA9AFEE|rigid:/mS1VYLraPVziGDiozsJyXHU+Vk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P19807 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317958|imex:IM-14275-369 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:54985C72998B74BA|rigid:UpQcnWrx1LSR4FBYvq42zxyMcpU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38695 uniprotkb:P19807 intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317991|imex:IM-14275-372 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) crc64:6906721BAC1A5F87 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:FF3327587AB7949D|rigid:JyXBTx9WaC4TF7Bm+bjqpt2/8iA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:P38234 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6317980|imex:IM-14275-371 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 intact-crc:258DE8D50EBF1756|rigid:rtyFhqSLjwaMNjl5Hf52qRosnp4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39719 uniprotkb:P19807 intact:EBI-20703|uniprotkb:Q05165|uniprotkb:D6VPG5|ensemblfungi:YAL053W intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:flc2_yeast(display_long)|uniprotkb:YAL053W(locus name)|uniprotkb:FLC2(gene name)|psi-mi:FLC2(display_short)|uniprotkb:FAD transporter 2(gene name synonym)|uniprotkb:TRP-like ion channel FLC2(gene name synonym) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318002|imex:IM-14275-373 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009348.2|sgd:S000000049|ensemblfungi:YAL053W(gene)|ensemblfungi:YAL053W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241|go:"GO:0055085"(transmembrane transport)|dip:DIP-6708N|mint:P39719 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:NOmMW54DNa0o7vM945DlZgVUy44559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:B60C944E41C6BE4A|rigid:gUw7SQLtVqZ3nvuv4vgGYSMoG/E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:P40260 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-10714|ensemblfungi:YGR121C|uniprotkb:D6VUQ2 psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:mep1_yeast(display_long)|uniprotkb:MEP1(gene name)|psi-mi:MEP1(display_short)|uniprotkb:YGR121C(locus name)|uniprotkb:G6331(orf name)|uniprotkb:AMT1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318024|imex:IM-14275-375 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) ensemblfungi:YGR121C(gene)|ensemblfungi:YGR121C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|sgd:S000003353|refseq:NP_011636.3|mint:P40260|dip:DIP-5530N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:VnoBl5jhQD24N0SbCLv68HCwl1U559292 intact-crc:F73C2F2171AA4BFF|rigid:B8WT0j0GHe/jjiZHjKAzr2oLRoQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39958 uniprotkb:P19807 intact:EBI-7517|uniprotkb:D3DM41|ensemblfungi:YER136W intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:gdi1_yeast(display_long)|uniprotkb:YER136W(locus name)|uniprotkb:GDI1(gene name)|psi-mi:GDI1(display_short)|uniprotkb:SEC19(gene name synonym)|uniprotkb:Secretory pathway GDP dissociation inhibitor(gene name synonym) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318013|imex:IM-14275-374 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011062.1|sgd:S000000938|mint:P39958|dip:DIP-785N|ensemblfungi:YER136W(gene)|ensemblfungi:YER136W_mRNA(transcript)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|rcsb pdb:1UKV|rcsb pdb:2BCG|rcsb pdb:3CPH|rcsb pdb:3CPI|rcsb pdb:3CPJ|reactome:R-SCE-6798695|reactome:R-SCE-8876198 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) crc64:48CF8D45FC031772 - figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AkWsG1VUBGxajiAMw0e0mOljZ6s559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:75A1330A9EF0C2FC|rigid:Q4ku6SjwhN1F6+KXmUzCHDtHxUs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P19807 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318046|imex:IM-14275-377 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:961A13AFD40F717D|rigid:PTskKeFnTkio9Ud2cYIr3d5DsZM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40474 uniprotkb:P19807 intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318035|imex:IM-14275-376 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:9B607B24FA8A1ACB|rigid:iW5AjzGdbPd8PkKNJXNfTdGafto false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53049 uniprotkb:P19807 intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318057|imex:IM-14275-378 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:B87EFCE3B55F2510|rigid:iZtdJ3TlT7AeB7aJHtUlFfHGGpU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:P53278 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318079|imex:IM-14275-380 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome) psi-mi:"MI:0469"(intact) - crc64:D482327C9274C026 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292 intact-crc:4A8583AAEC892C4E|rigid:5KWjz0IqwB0yY6D4BqPdaNKl8wA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53139 uniprotkb:P19807 intact:EBI-23908|uniprotkb:D6VU38|ensemblfungi:YGL108C intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:ygk8_yeast(display_long)|uniprotkb:G3070(orf name)|uniprotkb:YGL108C(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318068|imex:IM-14275-379 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003076|refseq:NP_011407.3|mint:P53139|ensemblfungi:YGL108C(gene)|ensemblfungi:YGL108C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6rg2zcMN57peeKKy/RolIDcNaLc559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:21B59F0B4C80CD7F|rigid:4vlu+GLlFxw/xIBrtKGOP0eAZm8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:P53388 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318101|imex:IM-14275-382 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) psi-mi:"MI:0469"(intact) - crc64:488A382656039D0B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 intact-crc:39B73B7B247966D3|rigid:krGLSCkzfjMMUuedd/CxqOczl9U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:P53283 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318090|imex:IM-14275-381 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 intact-crc:BBE520996EE1537D|rigid:Yep/60BJh8j6poTG9e9qGjIUufo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53832 uniprotkb:P19807 intact:EBI-2055941|uniprotkb:D6W0R1|ensemblfungi:YNL283C intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:wsc2_yeast(display_long)|uniprotkb:YNL283C(locus name)|uniprotkb:N0583(orf name)|uniprotkb:WSC2(gene name)|psi-mi:WSC2(display_short) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318123|imex:IM-14275-384 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014116.1|sgd:S000005227|interpro:IPR002889(Carbohydrate-binding WSC)|mint:P53832|ensemblfungi:YNL283C(gene)|ensemblfungi:YNL283C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5wadvTv6SxcIAb60yfnuGMfa8pY559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:39696A415F29D773|rigid:dxvX6ff0awlmmKM8g4oi5ODEeSc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53390 uniprotkb:P19807 intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318112|imex:IM-14275-383 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) crc64:2309338F36D96258 - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:A52169912DFE602A|rigid:Uw8o74Vo272mcoaBAdMpSXW0b1M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:P19807 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318145|imex:IM-14275-386 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:BC28C2C9F5DFCB6F|rigid:I3sG1iLV7rVFq3ayac2xkGf5gIE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02785 uniprotkb:P19807 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318134|imex:IM-14275-385 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:F218C7E45C6F9C32|rigid:Dj3PuwfWjw+rKZ/SrVa9ONa7eAg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06170 uniprotkb:P19807 intact:EBI-35994|uniprotkb:D6VYW8|ensemblfungi:YLR326W intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:yl326_yeast(display_long)|uniprotkb:YLR326W(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318167|imex:IM-14275-388 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013430.1|sgd:S000004318|mint:Q06170|dip:DIP-3995N|ensemblfungi:YLR326W(gene)|ensemblfungi:YLR326W_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR025187 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) crc64:724CD7833AA9B416 - figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ufkoj1kRp4Y9JTsgbL+3k8hzJyo559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:D23BF10AF36490F2|rigid:mtYkzBPMU5K2qh9vYWtIApPIJ6k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:Q05812 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-33150|uniprotkb:Q7LIF4|uniprotkb:D6VYL9|ensemblfungi:YLR219W psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:msc3_yeast(display_long)|uniprotkb:MSC3(gene name)|psi-mi:MSC3(display_short)|uniprotkb:YLR219W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318156|imex:IM-14275-387 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) sgd:S000004209|refseq:NP_013320.1|mint:Q05812|dip:DIP-6321N|ensemblfungi:YLR219W(gene)|ensemblfungi:YLR219W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007131"(reciprocal meiotic recombination) psi-mi:"MI:0469"(intact) - crc64:1962D638DB602B71 figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:xS8zCG9eHY8V0vNstOwUuTcI3Ao559292 intact-crc:3F9220EDF55A75A6|rigid:wN2sPEDgAfLzoEC435NIa/l+l3Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06451 uniprotkb:P19807 intact:EBI-34275|uniprotkb:D6W4F2|ensemblfungi:YPR156C intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:tpo3_yeast(display_long)|uniprotkb:TPO3(gene name)|psi-mi:TPO3(display_short)|uniprotkb:P9584.7(orf name)|uniprotkb:YPR156C(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318178|imex:IM-14275-389 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015482.1|sgd:S000006360|mint:Q06451|dip:DIP-3907N|ensemblfungi:YPR156C(gene)|ensemblfungi:YPR156C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) crc64:D260ED161F800502 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oVpx7Bjk/mK2Q7+/j05tX3gHw7k559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:9D2EDBB7BD65943F|rigid:Vy2JnFf6Zxvqj+JwKmKvRepCoWo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:Q07651 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318200|imex:IM-14275-391 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:FC33359A1222F9F2|rigid:cTwztIkHIRtq1s7iNLaNj+k0z/M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06689 uniprotkb:P19807 intact:EBI-38659|uniprotkb:D6VZ50|ensemblfungi:YLR413W intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:yl413_yeast(display_long)|uniprotkb:YLR413W(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318189|imex:IM-14275-390 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013517.1|sgd:S000004405|mint:Q06689|dip:DIP-5075N|ensemblfungi:YLR413W(gene)|ensemblfungi:YLR413W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0071944"(cell periphery)|interpro:IPR009571(SUR7) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) crc64:92E23436DC857E95 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AoTGKjLhw0NECrtuftZqLANonds559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:6098A88A0B16AAA5|rigid:7lMO9l+Yin9CPbz7rDpEa6JrrtU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07824 uniprotkb:P19807 intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318211|imex:IM-14275-392 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:029D014B311BE0F5|rigid:3UhLqaKA42lbAq/qtMM021NRhxE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12256 uniprotkb:P19807 intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318233|imex:IM-14275-394 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:0FF0C29CC5E94019|rigid:/R9O7w+xvV8mPgZdxvNkCUYmypY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:Q08967 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-36673|uniprotkb:D6W3E9|ensemblfungi:YPL221W psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:flc1_yeast(display_long)|uniprotkb:FAD transporter 1(gene name synonym)|uniprotkb:FLC1(gene name)|psi-mi:FLC1(display_short)|uniprotkb:TRP-like ion channel protein FLC1(gene name synonym)|uniprotkb:Heme utilization factor 1(gene name synonym)|uniprotkb:Bypass of PAM1 protein 1(gene name synonym)|uniprotkb:HUF1(gene name synonym)|uniprotkb:YPL221W(locus name)|uniprotkb:BOP1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318222|imex:IM-14275-393 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) refseq:NP_015103.1|sgd:S000006142|mint:Q08967|dip:DIP-3965N|ensemblfungi:YPL221W(gene)|ensemblfungi:YPL221W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055085"(transmembrane transport)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:r6CcZGEjxHUk2w0iBUBvnAPaFd4559292 intact-crc:4BBF9BD72BDE3553|rigid:woTPfSIYBtD/jDW5yfqzF0ZUdaU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12335 uniprotkb:P19807 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318255|imex:IM-14275-396 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) crc64:1056E7A1F3E82288 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:F7AF0515740FBED5|rigid:E7zzUnwlmH16kaDPINw1Lb4zZJo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:Q12270 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318244|imex:IM-14275-395 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:CCDF4D2E542B6D5F|rigid:NAaE4wK0R28ffpl1yo6uCqvAaxU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19881 uniprotkb:P20051 intact:EBI-35376|uniprotkb:Q07689|uniprotkb:D6VRC0|ensemblfungi:YDL236W intact:EBI-14380|uniprotkb:D6VZ56|ensemblfungi:YLR420W psi-mi:pnpp_yeast(display_long)|uniprotkb:PHO13(gene name)|psi-mi:PHO13(display_short)|uniprotkb:YDL236W(locus name) psi-mi:pyrc_yeast(display_long)|uniprotkb:L9931.1(orf name)|uniprotkb:YLR420W(locus name)|uniprotkb:URA4(gene name)|psi-mi:URA4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318277|imex:IM-14275-398 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010045.1|sgd:S000002395|mint:P19881|dip:DIP-1665N|ensemblfungi:YDL236W(gene)|ensemblfungi:YDL236W_mRNA(transcript)|go:"GO:0004035"(alkaline phosphatase activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008967"(phosphoglycolate phosphatase activity)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|interpro:IPR006349(2-phosphoglycolate phosphatase, eukaryotic)|interpro:IPR006357(HAD-superfamily hydrolase, subfamily IIA)|interpro:IPR023214|interpro:IPR036412 ensemblfungi:YLR420W(gene)|ensemblfungi:YLR420W_mRNA(transcript)|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006221"(pyrimidine nucleotide biosynthetic process)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR004721(Dihydroorotase homodimeric type)|interpro:IPR032466|rcsb pdb:6L0A|rcsb pdb:6L0B|rcsb pdb:6L0F|rcsb pdb:6L0G|rcsb pdb:6L0H|rcsb pdb:6L0I|rcsb pdb:6L0J|rcsb pdb:6L0K|rcsb pdb:7CA0|rcsb pdb:7CA1|refseq:NP_013524.1|sgd:S000004412|mint:P20051|dip:DIP-5074N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:QF2IfFJPZ9QZL+yEdO99vxt2WUc559292 rogid:JG5LhBH1JIglT/rsaJC7ehYxa+Q559292 intact-crc:BCA9A0F44314E53B|rigid:V3C42e6IiMxh1vvwnBS6bFGwiZQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19880 uniprotkb:P38315 intact:EBI-31265|uniprotkb:P22631|uniprotkb:Q06840|uniprotkb:D6VZG8|ensemblfungi:YML007W intact:EBI-20985|uniprotkb:D6VQL2|ensemblfungi:YBR216C psi-mi:ap1_yeast(display_long)|uniprotkb:YAP1(gene name)|psi-mi:YAP1(display_short)|uniprotkb:Phenanthroline resistance protein PAR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein PDR4(gene name synonym)|uniprotkb:PAR1(gene name synonym)|uniprotkb:PDR4(gene name synonym)|uniprotkb:SNQ3(gene name synonym)|uniprotkb:YML007W(locus name)|uniprotkb:YM9571.12(orf name) psi-mi:ybp1_yeast(display_long)|uniprotkb:YBP1(gene name)|psi-mi:YBP1(display_short)|uniprotkb:YBR216C(locus name)|uniprotkb:YBR1505(orf name)|uniprotkb:Activator of YAP1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318266|imex:IM-14275-397 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013707.1|sgd:S000004466|dip:DIP-1752N|mint:P19880|ensemblfungi:YML007W(gene)|ensemblfungi:YML007W_mRNA(transcript)|go:"GO:0000304"(response to singlet oxygen)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009408"(response to heat)|go:"GO:0042493"|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR013910(Transcription factor PAP1)|interpro:IPR023167|rcsb pdb:1SSE refseq:NP_009775.3|sgd:S000000420|mint:P38315|dip:DIP-4499N|ensemblfungi:YBR216C(gene)|ensemblfungi:YBR216C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0034599"(cellular response to oxidative stress)|interpro:IPR013877(Protein of unknown function DUF1760, fungi)|interpro:IPR040347 psi-mi:"MI:0469"(intact) crc64:192F20FA71027688 crc64:31F2B200CE34B32D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tBdBf1YyxGUsajaXCfnojqPjAoo559292 rogid:nr9DKgkbgvaqKM95piYhiIRix2A559292 intact-crc:3BD2CE437BA18146|rigid:RZhy8rfwvgn6cT5p5W9AP8oeO+M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08518 uniprotkb:P20434 intact:EBI-15767|uniprotkb:Q12738|uniprotkb:Q7Z9Y0|uniprotkb:D6W2K8|ensemblfungi:YOR151C intact:EBI-15781|uniprotkb:Q02121|ensemblfungi:YBR154C|uniprotkb:D6VQE9 psi-mi:rpb2_yeast(display_long)|uniprotkb:YOR151C(locus name)|uniprotkb:RPB2(gene name)|psi-mi:RPB2(display_short)|uniprotkb:RPB150(gene name synonym)|uniprotkb:RPO22(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym)|uniprotkb:B150(gene name synonym) psi-mi:rpab1_yeast(display_long)|uniprotkb:RPB5(gene name)|psi-mi:RPB5(display_short)|uniprotkb:YBR154C(locus name)|uniprotkb:YBR1204(orf name)|uniprotkb:RPA7(gene name synonym)|uniprotkb:RPC9(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide(gene name synonym)|uniprotkb:ABC27(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318299|imex:IM-14275-400 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005677|refseq:NP_014794.3|dip:DIP-14N|mint:P08518|ensemblfungi:YOR151C(gene)|ensemblfungi:YOR151C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519 rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|rcsb pdb:1WCM|rcsb pdb:1Y1V|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|rcsb pdb:2B63|rcsb pdb:2B8K|interpro:IPR020608|interpro:IPR020609|rcsb pdb:2E2H|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:1DZF|rcsb pdb:1I3Q|rcsb pdb:2E2I|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:5M5Y|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6H67|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:2E2J|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|ensemblfungi:YBR154C(gene)|ensemblfungi:YBR154C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4V1M|rcsb pdb:2JA5|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2JA6|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:2JA7|rcsb pdb:3GTG|rcsb pdb:2JA8|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:2NVQ|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4YM7|rcsb pdb:5C3E|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5G5L|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6H68|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|rcsb pdb:6UQ2|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-77075|reactome:R-SCE-9018519|refseq:NP_009712.1|sgd:S000000358|dip:DIP-71N|mint:P20434 psi-mi:"MI:0469"(intact) crc64:BABD03212C0A583E crc64:2A15F7114D69D829 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:OtaUDREazRORKDcfBajDLPlXovY559292 rogid:j/jAJ2fXWf4ebK1aWTWrKERGUpM559292 intact-crc:3BB51A6301C81044|rigid:xa2Gr4shEu2Zhz8R+eQ14QvLlr8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19881 uniprotkb:P38009 intact:EBI-35376|uniprotkb:Q07689|uniprotkb:D6VRC0|ensemblfungi:YDL236W intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 psi-mi:pnpp_yeast(display_long)|uniprotkb:PHO13(gene name)|psi-mi:PHO13(display_short)|uniprotkb:YDL236W(locus name) psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318288|imex:IM-14275-399 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010045.1|sgd:S000002395|mint:P19881|dip:DIP-1665N|ensemblfungi:YDL236W(gene)|ensemblfungi:YDL236W_mRNA(transcript)|go:"GO:0004035"(alkaline phosphatase activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008967"(phosphoglycolate phosphatase activity)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|interpro:IPR006349(2-phosphoglycolate phosphatase, eukaryotic)|interpro:IPR006357(HAD-superfamily hydrolase, subfamily IIA)|interpro:IPR023214|interpro:IPR036412 refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N psi-mi:"MI:0469"(intact) - crc64:8ABA71761B512242 figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:QF2IfFJPZ9QZL+yEdO99vxt2WUc559292 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 intact-crc:8955914E45E408B2|rigid:mhuXdMbm7sFpp6MHgwwT0NxVzCA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08518 uniprotkb:P20435 intact:EBI-15767|uniprotkb:Q12738|uniprotkb:Q7Z9Y0|uniprotkb:D6W2K8|ensemblfungi:YOR151C intact:EBI-15786|uniprotkb:D6W4I7|ensemblfungi:YPR187W psi-mi:rpb2_yeast(display_long)|uniprotkb:YOR151C(locus name)|uniprotkb:RPB2(gene name)|psi-mi:RPB2(display_short)|uniprotkb:RPB150(gene name synonym)|uniprotkb:RPO22(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym)|uniprotkb:B150(gene name synonym) psi-mi:rpab2_yeast(display_long)|uniprotkb:RPO26(gene name)|psi-mi:RPO26(display_short)|uniprotkb:RPB6(gene name synonym)|uniprotkb:YPR187W(locus name)|uniprotkb:P9677.8(orf name)|uniprotkb:DNA-directed RNA polymerases I, II, and III 23 kDa polypeptide(gene name synonym)|uniprotkb:ABC23(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318310|imex:IM-14275-401 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005677|refseq:NP_014794.3|dip:DIP-14N|mint:P08518|ensemblfungi:YOR151C(gene)|ensemblfungi:YOR151C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519 refseq:NP_015513.1|sgd:S000006391|dip:DIP-2194N|mint:P20435|ensemblfungi:YPR187W(gene)|ensemblfungi:YPR187W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR006110(RNA polymerase Rpb6)|interpro:IPR006111(DNA-directed RNA polymerase, 14 to 18 kDa subunit)|interpro:IPR012293(RNA polymerase subunit, RPB6/omega)|interpro:IPR020708|interpro:IPR028363|interpro:IPR036161|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4YM7|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5G5L|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-77075|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) crc64:BABD03212C0A583E crc64:AA3DEF529F94A5E4 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:OtaUDREazRORKDcfBajDLPlXovY559292 rogid:3kKsSGEw5OOi+Yp6budfnxfr8SQ559292 intact-crc:A40C1145243C4E10|rigid:O38vVILGal/43jZSiM9wm0ez3Ec false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20435 uniprotkb:P47035 intact:EBI-15786|uniprotkb:D6W4I7|ensemblfungi:YPR187W intact:EBI-25953|uniprotkb:D6VWA8|ensemblfungi:YJL076W psi-mi:rpab2_yeast(display_long)|uniprotkb:RPO26(gene name)|psi-mi:RPO26(display_short)|uniprotkb:RPB6(gene name synonym)|uniprotkb:YPR187W(locus name)|uniprotkb:P9677.8(orf name)|uniprotkb:DNA-directed RNA polymerases I, II, and III 23 kDa polypeptide(gene name synonym)|uniprotkb:ABC23(gene name synonym) psi-mi:net1_yeast(display_long)|uniprotkb:YJL076W(locus name)|uniprotkb:J1038(orf name)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:CFI1(gene name synonym)|uniprotkb:ESC5(gene name synonym)|uniprotkb:SRM8(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318332|imex:IM-14275-403 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015513.1|sgd:S000006391|dip:DIP-2194N|mint:P20435|ensemblfungi:YPR187W(gene)|ensemblfungi:YPR187W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR006110(RNA polymerase Rpb6)|interpro:IPR006111(DNA-directed RNA polymerase, 14 to 18 kDa subunit)|interpro:IPR012293(RNA polymerase subunit, RPB6/omega)|interpro:IPR020708|interpro:IPR028363|interpro:IPR036161|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4YM7|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5G5L|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-77075|reactome:R-SCE-9018519 refseq:NP_012459.1|sgd:S000003612|mint:P47035|dip:DIP-5153N|ensemblfungi:YJL076W(gene)|ensemblfungi:YJL076W_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007000"(nucleolus organization)|go:"GO:0007049"(cell cycle)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0030869"(RENT complex)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0051301"(cell division)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR018844|interpro:IPR043185 psi-mi:"MI:0469"(intact) crc64:AA3DEF529F94A5E4 crc64:80EDF9A8065EB5A2 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3kKsSGEw5OOi+Yp6budfnxfr8SQ559292 rogid:yjUIbOfA/bCZE9nMIjYS1QTn6EI559292 intact-crc:9F74470590437593|rigid:+iZtmEI8FZVo9QbLZIDLpJP/Q9U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20435 uniprotkb:P10964 intact:EBI-15786|uniprotkb:D6W4I7|ensemblfungi:YPR187W intact:EBI-15730|uniprotkb:Q99330|uniprotkb:D6W336|ensemblfungi:YOR341W psi-mi:rpab2_yeast(display_long)|uniprotkb:RPO26(gene name)|psi-mi:RPO26(display_short)|uniprotkb:RPB6(gene name synonym)|uniprotkb:YPR187W(locus name)|uniprotkb:P9677.8(orf name)|uniprotkb:DNA-directed RNA polymerases I, II, and III 23 kDa polypeptide(gene name synonym)|uniprotkb:ABC23(gene name synonym) psi-mi:rpa1_yeast(display_long)|uniprotkb:RPA190(gene name)|psi-mi:RPA190(display_short)|uniprotkb:RPA1(gene name synonym)|uniprotkb:RRN1(gene name synonym)|uniprotkb:YOR341W(locus name)|uniprotkb:O6276(orf name)|uniprotkb:DNA-directed RNA polymerase I 190 kDa polypeptide(gene name synonym)|uniprotkb:DNA-directed RNA polymerase I largest subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318321|imex:IM-14275-402 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015513.1|sgd:S000006391|dip:DIP-2194N|mint:P20435|ensemblfungi:YPR187W(gene)|ensemblfungi:YPR187W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR006110(RNA polymerase Rpb6)|interpro:IPR006111(DNA-directed RNA polymerase, 14 to 18 kDa subunit)|interpro:IPR012293(RNA polymerase subunit, RPB6/omega)|interpro:IPR020708|interpro:IPR028363|interpro:IPR036161|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4YM7|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5G5L|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-77075|reactome:R-SCE-9018519 sgd:S000005868|refseq:NP_014986.3|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR015699(DNA-directed RNA pol I, largest subunit)|interpro:IPR038120|interpro:IPR042102|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|ensemblfungi:YOR341W(gene)|ensemblfungi:YOR341W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0008270"(zinc ion binding)|dip:DIP-999N|mint:P10964 psi-mi:"MI:0469"(intact) crc64:AA3DEF529F94A5E4 crc64:DF65A7AA459D5E6D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3kKsSGEw5OOi+Yp6budfnxfr8SQ559292 rogid:krXuLY5fTE34McW4bnuPqns5Oy4559292 intact-crc:B8A718954413BA04|rigid:3DWwpkZpVSHQoAuUvbSLcF6hH3A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20485 uniprotkb:P25293 intact:EBI-9699|ensemblfungi:YLR133W|uniprotkb:D6VYC8 intact:EBI-11850|uniprotkb:P87196|ensemblfungi:YKR048C|uniprotkb:D6VXA9 psi-mi:kich_yeast(display_long)|uniprotkb:CKI1(gene name)|psi-mi:CKI1(display_short)|uniprotkb:CKI(gene name synonym)|uniprotkb:YLR133W(locus name)|uniprotkb:L3130(orf name)|uniprotkb:L9606.8(orf name)|uniprotkb:"ATP:choline phosphotransferase"(gene name synonym) psi-mi:nap1_yeast(display_long)|uniprotkb:NAP1(gene name)|psi-mi:NAP1(display_short)|uniprotkb:YKR048C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318354|imex:IM-14275-405 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR133W(gene)|ensemblfungi:YLR133W_mRNA(transcript)|go:"GO:0004103"(choline kinase activity)|go:"GO:0004305"(ethanolamine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|interpro:IPR007521(Choline kinase, N-terminal)|interpro:IPR011009(Protein kinase-like)|reactome:R-SCE-1483191|reactome:R-SCE-1483213|refseq:NP_013234.1|sgd:S000004123|mint:P20485|dip:DIP-2617N ensemblfungi:YKR048C(gene)|ensemblfungi:YKR048C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032153"(cell division site)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0098841"(protein localization to cell division site after cytokinesis)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|rcsb pdb:2AYU|rcsb pdb:2Z2R|rcsb pdb:5G2E|go:"GO:0032174"(cellular bud neck septin collar)|refseq:NP_012974.1|sgd:S000001756|dip:DIP-1380N|mint:P25293 psi-mi:"MI:0469"(intact) crc64:68C395B9CC120A0E crc64:C0F97FBA1B9EEA83 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:JAeKrnUWBWBElM5OPJ0A43K+pGQ559292 rogid:MBxVJ0JmlEg5coqnQd6uoSX2uC0559292 intact-crc:C9B659B4BCFE813A|rigid:6F55W2+K0zn4/5Ve+lH6m34Y7Lg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21304 uniprotkb:P20447 intact:EBI-14328|uniprotkb:D6VYJ9|ensemblfungi:YLR196W intact:EBI-5608|uniprotkb:D6VU66|ensemblfungi:YGL078C psi-mi:pwp1_yeast(display_long)|uniprotkb:L8167.10(orf name)|uniprotkb:YLR196W(locus name)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short) psi-mi:dbp3_yeast(display_long)|uniprotkb:YGL078C(locus name)|uniprotkb:DBP3(gene name)|psi-mi:DBP3(display_short)|uniprotkb:DEAD box protein 3(gene name synonym)|uniprotkb:Helicase CA3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318343|imex:IM-14275-404 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013297.1|sgd:S000004186|ensemblfungi:YLR196W(gene)|ensemblfungi:YLR196W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR044285|mint:P21304|dip:DIP-4203N sgd:S000003046|refseq:NP_011437.3|dip:DIP-2668N|mint:P20447|ensemblfungi:YGL078C(gene)|ensemblfungi:YGL078C_mRNA(transcript)|go:"GO:0000464"("endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417 psi-mi:"MI:0469"(intact) crc64:FC0189B289494AB5 - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Q1nPXtlkpIw8JosaiYX0PSVNaSw559292 rogid:9ltHUfhcU8nfN3bxsmkabo8A2L4559292 intact-crc:291B010AF0DEEB7C|rigid:OYHrWYsFn0gcwheQJp74m2PxhhY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06706 uniprotkb:P20604 intact:EBI-9068|uniprotkb:O00036|ensemblfungi:YLR384C|uniprotkb:D6VZ19 intact:EBI-13707|uniprotkb:D6VRU8|ensemblfungi:YDL047W psi-mi:elp1_yeast(display_long)|uniprotkb:IKI3(gene name)|psi-mi:IKI3(display_short)|uniprotkb:YLR384C(locus name)|uniprotkb:L3502.7(orf name)|uniprotkb:ELP1(gene name synonym)|uniprotkb:TOT1(gene name synonym)|uniprotkb:Protein IKI3(gene name synonym)|uniprotkb:Gamma-toxin target 1(gene name synonym) psi-mi:pp11_yeast(display_long)|uniprotkb:SIT4(gene name)|psi-mi:SIT4(display_short)|uniprotkb:PPH1(gene name synonym)|uniprotkb:YDL047W(locus name)|uniprotkb:D2693(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318376|imex:IM-14275-407 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR384C(gene)|ensemblfungi:YLR384C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002926"(tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015031"(protein transport)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR006849(IKI3)|rcsb pdb:5CQS|rcsb pdb:6QK7|refseq:NP_013488.3|sgd:S000004376|dip:DIP-2384N|mint:Q06706 refseq:NP_010236.1|sgd:S000002205|ensemblfungi:YDL047W(gene)|ensemblfungi:YDL047W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0051301"(cell division)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|reactome:R-SCE-204005|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0016311"(dephosphorylation)|go:"GO:0031929"(TOR signaling)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046872"(metal ion binding)|mint:P20604|dip:DIP-5850N psi-mi:"MI:0469"(intact) crc64:7AEB1C0BA99282F6 crc64:AF52BC65E4E715EC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:EnFV08kc3WWB6YjyTKs7hSDvjPA559292 rogid:Up3F/fGsTK1vYjho+dJ/TDVIEM0559292 intact-crc:26048EFC83C4A9EE|rigid:c0b74H8gxdv6KYuUdhzCmxvf5ZU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43612 uniprotkb:P20604 intact:EBI-16370|ensemblfungi:YFR040W|uniprotkb:Q96VG4|uniprotkb:D6VTS3 intact:EBI-13707|uniprotkb:D6VRU8|ensemblfungi:YDL047W psi-mi:sa155_yeast(display_long)|uniprotkb:SAP155(gene name)|psi-mi:SAP155(display_short)|uniprotkb:YFR040W(locus name) psi-mi:pp11_yeast(display_long)|uniprotkb:SIT4(gene name)|psi-mi:SIT4(display_short)|uniprotkb:PPH1(gene name synonym)|uniprotkb:YDL047W(locus name)|uniprotkb:D2693(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318365|imex:IM-14275-406 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YFR040W(gene)|ensemblfungi:YFR040W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|reactome:R-SCE-204005|refseq:NP_116698.3|sgd:S000001936|dip:DIP-5852N|mint:P43612 refseq:NP_010236.1|sgd:S000002205|ensemblfungi:YDL047W(gene)|ensemblfungi:YDL047W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0051301"(cell division)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|reactome:R-SCE-204005|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0016311"(dephosphorylation)|go:"GO:0031929"(TOR signaling)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046872"(metal ion binding)|mint:P20604|dip:DIP-5850N psi-mi:"MI:0469"(intact) crc64:50CDC17130333022 crc64:AF52BC65E4E715EC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:OX+DqsaQW7F5rHzNB2R69wYu6YE559292 rogid:Up3F/fGsTK1vYjho+dJ/TDVIEM0559292 intact-crc:4383420D4B8A2A36|rigid:1SZvZHDaYOH3sQ/2s3zJpHsXvm0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P21147 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-2098|ensemblfungi:YGL055W|uniprotkb:D6VU86|uniprotkb:E9P911 psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:aco1_yeast(display_long)|uniprotkb:OLE1(gene name)|psi-mi:OLE1(display_short)|uniprotkb:Stearoyl-CoA desaturase 1(gene name synonym)|uniprotkb:Fatty acid desaturase 1(gene name synonym)|uniprotkb:YGL055W(locus name)|uniprotkb:Delta 9 fatty acid desaturase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318398|imex:IM-14275-409 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 ensemblfungi:YGL055W(gene)|ensemblfungi:YGL055W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0004768"(stearoyl-CoA 9-desaturase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|sgd:S000003023|refseq:NP_011460.3|dip:DIP-5026N|mint:P21147|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR001522(Fatty acid desaturase, type 1, C-terminal)|interpro:IPR005804(Fatty acid desaturase, type 1)|interpro:IPR009160(Delta-9 acyl-CoA desaturase with haem/steroid binding region)|interpro:IPR015876(Fatty acid desaturase, type 1, core)|interpro:IPR018506|interpro:IPR036400 psi-mi:"MI:0469"(intact) - crc64:A6CC78DD4210ECCA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:Ibp4I76IX/sMf5kLO05pTBZ3TNE559292 intact-crc:CF307EEA7CBFEA5F|rigid:Xa+nl7qJFiwfdKVP+hWKzIPMR6w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06142 uniprotkb:P20676 intact:EBI-9145|ensemblfungi:YLR347C|uniprotkb:D6VYY6 intact:EBI-12392|ensemblfungi:YOR098C|uniprotkb:D6W2F9 psi-mi:imb1_yeast(display_long)|uniprotkb:KAP95(gene name)|psi-mi:KAP95(display_short)|uniprotkb:YLR347C(locus name)|uniprotkb:L8300.15(orf name)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Karyopherin-95(gene name synonym)|uniprotkb:Importin-95(gene name synonym) psi-mi:nup1_yeast(display_long)|uniprotkb:NUP1(gene name)|psi-mi:NUP1(display_short)|uniprotkb:YOR098C(locus name)|uniprotkb:YOR3182C(orf name)|uniprotkb:Nuclear pore protein NUP1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318387|imex:IM-14275-408 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3EA5|rcsb pdb:3ND2|rcsb pdb:5OWU|reactome:R-SCE-2995383|reactome:R-SCE-6798695|ensemblfungi:YLR347C(gene)|ensemblfungi:YLR347C_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|rcsb pdb:2BKU|go:"GO:0006612"(protein targeting to membrane)|refseq:NP_013451.1|sgd:S000004339|dip:DIP-2357N|mint:Q06142 ensemblfungi:YOR098C(gene)|ensemblfungi:YOR098C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|interpro:IPR026054|rcsb pdb:4C31|rcsb pdb:4MBE|rcsb pdb:5OWU|go:"GO:0006607"(NLS-bearing protein import into nucleus)|refseq:NP_014741.1|sgd:S000005624|mint:P20676|dip:DIP-81N psi-mi:"MI:0469"(intact) crc64:ED530F5313E75B06 crc64:4AC23567D2FB53CC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ebWeXaUKiBFWgjdv9s2pz1GIqgI559292 rogid:X1AjTIzoXjQ7vXlKzI88m7xfu6w559292 intact-crc:F05E87D7D39781B0|rigid:hA0p11QpJ31fA4eVSQFCF8EPngc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21147 uniprotkb:P21147 intact:EBI-2098|ensemblfungi:YGL055W|uniprotkb:D6VU86|uniprotkb:E9P911 intact:EBI-2098|ensemblfungi:YGL055W|uniprotkb:D6VU86|uniprotkb:E9P911 psi-mi:aco1_yeast(display_long)|uniprotkb:OLE1(gene name)|psi-mi:OLE1(display_short)|uniprotkb:Stearoyl-CoA desaturase 1(gene name synonym)|uniprotkb:Fatty acid desaturase 1(gene name synonym)|uniprotkb:YGL055W(locus name)|uniprotkb:Delta 9 fatty acid desaturase(gene name synonym) psi-mi:aco1_yeast(display_long)|uniprotkb:OLE1(gene name)|psi-mi:OLE1(display_short)|uniprotkb:Stearoyl-CoA desaturase 1(gene name synonym)|uniprotkb:Fatty acid desaturase 1(gene name synonym)|uniprotkb:YGL055W(locus name)|uniprotkb:Delta 9 fatty acid desaturase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318409|imex:IM-14275-410 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL055W(gene)|ensemblfungi:YGL055W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0004768"(stearoyl-CoA 9-desaturase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|sgd:S000003023|refseq:NP_011460.3|dip:DIP-5026N|mint:P21147|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR001522(Fatty acid desaturase, type 1, C-terminal)|interpro:IPR005804(Fatty acid desaturase, type 1)|interpro:IPR009160(Delta-9 acyl-CoA desaturase with haem/steroid binding region)|interpro:IPR015876(Fatty acid desaturase, type 1, core)|interpro:IPR018506|interpro:IPR036400 ensemblfungi:YGL055W(gene)|ensemblfungi:YGL055W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0004768"(stearoyl-CoA 9-desaturase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|sgd:S000003023|refseq:NP_011460.3|dip:DIP-5026N|mint:P21147|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR001522(Fatty acid desaturase, type 1, C-terminal)|interpro:IPR005804(Fatty acid desaturase, type 1)|interpro:IPR009160(Delta-9 acyl-CoA desaturase with haem/steroid binding region)|interpro:IPR015876(Fatty acid desaturase, type 1, core)|interpro:IPR018506|interpro:IPR036400 psi-mi:"MI:0469"(intact) crc64:A6CC78DD4210ECCA crc64:A6CC78DD4210ECCA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ibp4I76IX/sMf5kLO05pTBZ3TNE559292 rogid:Ibp4I76IX/sMf5kLO05pTBZ3TNE559292 intact-crc:6AA04F8F100FDF32|rigid:fjAsHbawBMM+SJlhuW21ZblUZ04 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:P21147 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-2098|ensemblfungi:YGL055W|uniprotkb:D6VU86|uniprotkb:E9P911 psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:aco1_yeast(display_long)|uniprotkb:OLE1(gene name)|psi-mi:OLE1(display_short)|uniprotkb:Stearoyl-CoA desaturase 1(gene name synonym)|uniprotkb:Fatty acid desaturase 1(gene name synonym)|uniprotkb:YGL055W(locus name)|uniprotkb:Delta 9 fatty acid desaturase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318431|imex:IM-14275-412 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N ensemblfungi:YGL055W(gene)|ensemblfungi:YGL055W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0004768"(stearoyl-CoA 9-desaturase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|sgd:S000003023|refseq:NP_011460.3|dip:DIP-5026N|mint:P21147|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR001522(Fatty acid desaturase, type 1, C-terminal)|interpro:IPR005804(Fatty acid desaturase, type 1)|interpro:IPR009160(Delta-9 acyl-CoA desaturase with haem/steroid binding region)|interpro:IPR015876(Fatty acid desaturase, type 1, core)|interpro:IPR018506|interpro:IPR036400 psi-mi:"MI:0469"(intact) - crc64:A6CC78DD4210ECCA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:Ibp4I76IX/sMf5kLO05pTBZ3TNE559292 intact-crc:0DE38FC3BF7D3ADC|rigid:CVUFfpozXe1SCGPhmHE0amev588 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:P21147 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-2098|ensemblfungi:YGL055W|uniprotkb:D6VU86|uniprotkb:E9P911 psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:aco1_yeast(display_long)|uniprotkb:OLE1(gene name)|psi-mi:OLE1(display_short)|uniprotkb:Stearoyl-CoA desaturase 1(gene name synonym)|uniprotkb:Fatty acid desaturase 1(gene name synonym)|uniprotkb:YGL055W(locus name)|uniprotkb:Delta 9 fatty acid desaturase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318420|imex:IM-14275-411 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N ensemblfungi:YGL055W(gene)|ensemblfungi:YGL055W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0004768"(stearoyl-CoA 9-desaturase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|sgd:S000003023|refseq:NP_011460.3|dip:DIP-5026N|mint:P21147|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR001522(Fatty acid desaturase, type 1, C-terminal)|interpro:IPR005804(Fatty acid desaturase, type 1)|interpro:IPR009160(Delta-9 acyl-CoA desaturase with haem/steroid binding region)|interpro:IPR015876(Fatty acid desaturase, type 1, core)|interpro:IPR018506|interpro:IPR036400 psi-mi:"MI:0469"(intact) crc64:8B7F009521F72C15 crc64:A6CC78DD4210ECCA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:Ibp4I76IX/sMf5kLO05pTBZ3TNE559292 intact-crc:B4167D1A80053D56|rigid:jRkNg+Q1/3g/H6m9Lz/yHiwDchw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21147 uniprotkb:P38264 intact:EBI-2098|ensemblfungi:YGL055W|uniprotkb:D6VU86|uniprotkb:E9P911 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 psi-mi:aco1_yeast(display_long)|uniprotkb:OLE1(gene name)|psi-mi:OLE1(display_short)|uniprotkb:Stearoyl-CoA desaturase 1(gene name synonym)|uniprotkb:Fatty acid desaturase 1(gene name synonym)|uniprotkb:YGL055W(locus name)|uniprotkb:Delta 9 fatty acid desaturase(gene name synonym) psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318453|imex:IM-14275-414 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL055W(gene)|ensemblfungi:YGL055W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0004768"(stearoyl-CoA 9-desaturase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|sgd:S000003023|refseq:NP_011460.3|dip:DIP-5026N|mint:P21147|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR001522(Fatty acid desaturase, type 1, C-terminal)|interpro:IPR005804(Fatty acid desaturase, type 1)|interpro:IPR009160(Delta-9 acyl-CoA desaturase with haem/steroid binding region)|interpro:IPR015876(Fatty acid desaturase, type 1, core)|interpro:IPR018506|interpro:IPR036400 refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N psi-mi:"MI:0469"(intact) crc64:A6CC78DD4210ECCA - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ibp4I76IX/sMf5kLO05pTBZ3TNE559292 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 intact-crc:5A8DA4CB01D9A743|rigid:0biZb5KpzWJo9p3zGe1ZXbjJVz0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36076 uniprotkb:P21147 intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W intact:EBI-2098|ensemblfungi:YGL055W|uniprotkb:D6VU86|uniprotkb:E9P911 psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short) psi-mi:aco1_yeast(display_long)|uniprotkb:OLE1(gene name)|psi-mi:OLE1(display_short)|uniprotkb:Stearoyl-CoA desaturase 1(gene name synonym)|uniprotkb:Fatty acid desaturase 1(gene name synonym)|uniprotkb:YGL055W(locus name)|uniprotkb:Delta 9 fatty acid desaturase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318442|imex:IM-14275-413 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783 ensemblfungi:YGL055W(gene)|ensemblfungi:YGL055W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0004768"(stearoyl-CoA 9-desaturase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|sgd:S000003023|refseq:NP_011460.3|dip:DIP-5026N|mint:P21147|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR001522(Fatty acid desaturase, type 1, C-terminal)|interpro:IPR005804(Fatty acid desaturase, type 1)|interpro:IPR009160(Delta-9 acyl-CoA desaturase with haem/steroid binding region)|interpro:IPR015876(Fatty acid desaturase, type 1, core)|interpro:IPR018506|interpro:IPR036400 psi-mi:"MI:0469"(intact) - crc64:A6CC78DD4210ECCA figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Li7vZOassm4PC5fW111/j5ivgEc559292 rogid:Ibp4I76IX/sMf5kLO05pTBZ3TNE559292 intact-crc:967BDB12243B41AF|rigid:+NZTMDZKzG6uYZv0nqfsKRSnZis false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47155 uniprotkb:P21147 intact:EBI-2051644|uniprotkb:D6VWT7|ensemblfungi:YJR118C intact:EBI-2098|ensemblfungi:YGL055W|uniprotkb:D6VU86|uniprotkb:E9P911 psi-mi:ilm1_yeast(display_long)|uniprotkb:Increased loss of mitochondrial DNA protein 1(gene name synonym)|uniprotkb:J2033(orf name)|uniprotkb:ILM1(gene name)|psi-mi:ILM1(display_short)|uniprotkb:YJR118C(locus name) psi-mi:aco1_yeast(display_long)|uniprotkb:OLE1(gene name)|psi-mi:OLE1(display_short)|uniprotkb:Stearoyl-CoA desaturase 1(gene name synonym)|uniprotkb:Fatty acid desaturase 1(gene name synonym)|uniprotkb:YGL055W(locus name)|uniprotkb:Delta 9 fatty acid desaturase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318475|imex:IM-14275-416 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003879|interpro:IPR018815|refseq:NP_012652.3|mint:P47155|ensemblfungi:YJR118C(gene)|ensemblfungi:YJR118C_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane) ensemblfungi:YGL055W(gene)|ensemblfungi:YGL055W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0004768"(stearoyl-CoA 9-desaturase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|sgd:S000003023|refseq:NP_011460.3|dip:DIP-5026N|mint:P21147|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR001522(Fatty acid desaturase, type 1, C-terminal)|interpro:IPR005804(Fatty acid desaturase, type 1)|interpro:IPR009160(Delta-9 acyl-CoA desaturase with haem/steroid binding region)|interpro:IPR015876(Fatty acid desaturase, type 1, core)|interpro:IPR018506|interpro:IPR036400 psi-mi:"MI:0469"(intact) - crc64:A6CC78DD4210ECCA figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BrQhbXGvUjNG6Bt5c0J7T8qzMeI559292 rogid:Ibp4I76IX/sMf5kLO05pTBZ3TNE559292 intact-crc:1169439E224E79CD|rigid:oTsXIpHCly6U0xDyPZAAXEft2R8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40540 uniprotkb:P21147 intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C intact:EBI-2098|ensemblfungi:YGL055W|uniprotkb:D6VU86|uniprotkb:E9P911 psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:aco1_yeast(display_long)|uniprotkb:OLE1(gene name)|psi-mi:OLE1(display_short)|uniprotkb:Stearoyl-CoA desaturase 1(gene name synonym)|uniprotkb:Fatty acid desaturase 1(gene name synonym)|uniprotkb:YGL055W(locus name)|uniprotkb:Delta 9 fatty acid desaturase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318464|imex:IM-14275-415 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX ensemblfungi:YGL055W(gene)|ensemblfungi:YGL055W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0004768"(stearoyl-CoA 9-desaturase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|sgd:S000003023|refseq:NP_011460.3|dip:DIP-5026N|mint:P21147|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR001522(Fatty acid desaturase, type 1, C-terminal)|interpro:IPR005804(Fatty acid desaturase, type 1)|interpro:IPR009160(Delta-9 acyl-CoA desaturase with haem/steroid binding region)|interpro:IPR015876(Fatty acid desaturase, type 1, core)|interpro:IPR018506|interpro:IPR036400 psi-mi:"MI:0469"(intact) crc64:6DBEEEE7722203B0 crc64:A6CC78DD4210ECCA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 rogid:Ibp4I76IX/sMf5kLO05pTBZ3TNE559292 intact-crc:A214D221BDC7CFBC|rigid:L381nRZRlTlEdHIHaQ5lJiC+JfM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21147 uniprotkb:P54837 intact:EBI-2098|ensemblfungi:YGL055W|uniprotkb:D6VU86|uniprotkb:E9P911 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:aco1_yeast(display_long)|uniprotkb:OLE1(gene name)|psi-mi:OLE1(display_short)|uniprotkb:Stearoyl-CoA desaturase 1(gene name synonym)|uniprotkb:Fatty acid desaturase 1(gene name synonym)|uniprotkb:YGL055W(locus name)|uniprotkb:Delta 9 fatty acid desaturase(gene name synonym) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318486|imex:IM-14275-417 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL055W(gene)|ensemblfungi:YGL055W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0004768"(stearoyl-CoA 9-desaturase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|sgd:S000003023|refseq:NP_011460.3|dip:DIP-5026N|mint:P21147|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR001522(Fatty acid desaturase, type 1, C-terminal)|interpro:IPR005804(Fatty acid desaturase, type 1)|interpro:IPR009160(Delta-9 acyl-CoA desaturase with haem/steroid binding region)|interpro:IPR015876(Fatty acid desaturase, type 1, core)|interpro:IPR018506|interpro:IPR036400 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:A6CC78DD4210ECCA - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ibp4I76IX/sMf5kLO05pTBZ3TNE559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:CD29EA5873E997BF|rigid:wBWAgEEinNd2C47XZxQiiC7JJqM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23638 uniprotkb:P21242 intact:EBI-13967|ensemblfungi:YGR135W|uniprotkb:D6VUR7 intact:EBI-13963|ensemblfungi:YOR362C|uniprotkb:D6W357 psi-mi:psa3_yeast(display_long)|uniprotkb:PRE9(gene name)|psi-mi:PRE9(display_short)|uniprotkb:YGR135W(locus name)|uniprotkb:PRS5(gene name synonym)|uniprotkb:Proteasome component Y13(gene name synonym)|uniprotkb:Macropain subunit Y13(gene name synonym)|uniprotkb:Proteinase YSCE subunit 13(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit Y13(gene name synonym) psi-mi:psa7_yeast(display_long)|uniprotkb:PRE10(gene name)|psi-mi:PRE10(display_short)|uniprotkb:PRC1(gene name synonym)|uniprotkb:PRS1(gene name synonym)|uniprotkb:O6650(orf name)|uniprotkb:YOR362C(locus name)|uniprotkb:Proteasome component C1(gene name synonym)|uniprotkb:Macropain subunit C1(gene name synonym)|uniprotkb:Proteinase YSCE subunit 1(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318508|imex:IM-14275-419 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003367|ensemblfungi:YGR135W(gene)|ensemblfungi:YGR135W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0080129"(proteasome core complex assembly)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:3OKJ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NO1|rcsb pdb:4NNN|rcsb pdb:4NO6|rcsb pdb:4NNW|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|rcsb pdb:6J2Q|interpro:IPR001353(20S proteasome, A and B subunits)|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QVL|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|reactome:R-SCE-983168|reactome:R-SCE-8948751|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4QZ2|rcsb pdb:4Y70|rcsb pdb:4Y8H|rcsb pdb:4Y74|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y75|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y8R|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:4YA3|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:3OEV|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5FGF|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L60|rcsb pdb:5L5Z|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|refseq:NP_011651.3|mint:P23638|dip:DIP-2823N ensemblfungi:YOR362C(gene)|ensemblfungi:YOR362C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR029055|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR037555|interpro:IPR001353(20S proteasome, A and B subunits)|rcsb pdb:1FNT|interpro:IPR023332|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QW6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4Y7Y|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5A5B|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5D0X|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L5E|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5L67|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6HTC|rcsb pdb:6FVW|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6FVX|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6HV4|rcsb pdb:6G8M|rcsb pdb:6HV5|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|rcsb pdb:6HW5|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-5668541|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:1G0U|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:3SDI|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QLS|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|refseq:NP_015007.1|sgd:S000005889|mint:P21242|dip:DIP-1526N psi-mi:"MI:0469"(intact) crc64:B43BB05233A01A9E crc64:1E51D904CF336747 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5F6HrO7MputR68OA/1SAdFfJa4g559292 rogid:tVLLjztJDttaRM40dHah/J06g0E559292 intact-crc:7A2097FB3FEFF0E6|rigid:yQS9ge67+XUXrBOFx98Oxy7f4kc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12256 uniprotkb:P21147 intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C intact:EBI-2098|ensemblfungi:YGL055W|uniprotkb:D6VU86|uniprotkb:E9P911 psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:aco1_yeast(display_long)|uniprotkb:OLE1(gene name)|psi-mi:OLE1(display_short)|uniprotkb:Stearoyl-CoA desaturase 1(gene name synonym)|uniprotkb:Fatty acid desaturase 1(gene name synonym)|uniprotkb:YGL055W(locus name)|uniprotkb:Delta 9 fatty acid desaturase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318497|imex:IM-14275-418 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 ensemblfungi:YGL055W(gene)|ensemblfungi:YGL055W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0004768"(stearoyl-CoA 9-desaturase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|sgd:S000003023|refseq:NP_011460.3|dip:DIP-5026N|mint:P21147|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR001522(Fatty acid desaturase, type 1, C-terminal)|interpro:IPR005804(Fatty acid desaturase, type 1)|interpro:IPR009160(Delta-9 acyl-CoA desaturase with haem/steroid binding region)|interpro:IPR015876(Fatty acid desaturase, type 1, core)|interpro:IPR018506|interpro:IPR036400 psi-mi:"MI:0469"(intact) - crc64:A6CC78DD4210ECCA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 rogid:Ibp4I76IX/sMf5kLO05pTBZ3TNE559292 intact-crc:74D5C0C5743DD52B|rigid:4d20eXz7dm5/tjYn/loaCug8WO8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21242 uniprotkb:P23639 intact:EBI-13963|ensemblfungi:YOR362C|uniprotkb:D6W357 intact:EBI-13959|ensemblfungi:YML092C|uniprotkb:D6W0J3 psi-mi:psa7_yeast(display_long)|uniprotkb:PRE10(gene name)|psi-mi:PRE10(display_short)|uniprotkb:PRC1(gene name synonym)|uniprotkb:PRS1(gene name synonym)|uniprotkb:O6650(orf name)|uniprotkb:YOR362C(locus name)|uniprotkb:Proteasome component C1(gene name synonym)|uniprotkb:Macropain subunit C1(gene name synonym)|uniprotkb:Proteinase YSCE subunit 1(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C1(gene name synonym) psi-mi:psa2_yeast(display_long)|uniprotkb:PRE8(gene name)|psi-mi:PRE8(display_short)|uniprotkb:PRS4(gene name synonym)|uniprotkb:YML092C(locus name)|uniprotkb:Proteasome component Y7(gene name synonym)|uniprotkb:Macropain subunit Y7(gene name synonym)|uniprotkb:Proteinase YSCE subunit 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit Y7(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318519|imex:IM-14275-420 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR362C(gene)|ensemblfungi:YOR362C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR029055|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR037555|interpro:IPR001353(20S proteasome, A and B subunits)|rcsb pdb:1FNT|interpro:IPR023332|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QW6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4Y7Y|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5A5B|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5D0X|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L5E|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5L67|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6HTC|rcsb pdb:6FVW|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6FVX|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6HV4|rcsb pdb:6G8M|rcsb pdb:6HV5|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|rcsb pdb:6HW5|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-5668541|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:1G0U|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:3SDI|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QLS|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|refseq:NP_015007.1|sgd:S000005889|mint:P21242|dip:DIP-1526N rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:2ZCY|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:3OEV|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4INU|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5CZ5|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5JHR|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QV4|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:5MPC|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6EF3|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWF|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HVY|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-983168|reactome:R-SCE-8948751|ensemblfungi:YML092C(gene)|ensemblfungi:YML092C_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|refseq:NP_013618.1|sgd:S000004557|mint:P23639|dip:DIP-2822N psi-mi:"MI:0469"(intact) crc64:1E51D904CF336747 crc64:12D7DFB1AA10E9FE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tVLLjztJDttaRM40dHah/J06g0E559292 rogid:HiJr+UwwGu+wQImwgq3TiHYELx8559292 intact-crc:E5999CDD1A1BAEB2|rigid:4Ly+rNvN3Ju+/5lLYBPnixwr/VE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23639 uniprotkb:P21243 intact:EBI-13959|ensemblfungi:YML092C|uniprotkb:D6W0J3 intact:EBI-13975|uniprotkb:P15708|ensemblfungi:YGL011C|uniprotkb:D6VUC6 psi-mi:psa2_yeast(display_long)|uniprotkb:PRE8(gene name)|psi-mi:PRE8(display_short)|uniprotkb:PRS4(gene name synonym)|uniprotkb:YML092C(locus name)|uniprotkb:Proteasome component Y7(gene name synonym)|uniprotkb:Macropain subunit Y7(gene name synonym)|uniprotkb:Proteinase YSCE subunit 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit Y7(gene name synonym) psi-mi:psa1_yeast(display_long)|uniprotkb:SCL1(gene name)|psi-mi:SCL1(display_short)|uniprotkb:PRC2(gene name synonym)|uniprotkb:PRS2(gene name synonym)|uniprotkb:YGL011C(locus name)|uniprotkb:Proteasome component C7-alpha(gene name synonym)|uniprotkb:Macropain subunit C7-alpha(gene name synonym)|uniprotkb:Proteinase YSCE subunit 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex C7(gene name synonym)|uniprotkb:Proteasome component Y8(gene name synonym)|uniprotkb:SCL1 suppressor protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318541|imex:IM-14275-422 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:2ZCY|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:3OEV|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4INU|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5CZ5|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5JHR|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QV4|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:5MPC|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6EF3|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWF|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HVY|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-983168|reactome:R-SCE-8948751|ensemblfungi:YML092C(gene)|ensemblfungi:YML092C_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|refseq:NP_013618.1|sgd:S000004557|mint:P23639|dip:DIP-2822N sgd:S000002979|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|ensemblfungi:YGL011C(gene)|ensemblfungi:YGL011C_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034642|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y69|rcsb pdb:4Y8K|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y8L|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|refseq:NP_011504.3|mint:P21243|dip:DIP-2810N psi-mi:"MI:0469"(intact) crc64:12D7DFB1AA10E9FE crc64:5B938C862BC8D7EB figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HiJr+UwwGu+wQImwgq3TiHYELx8559292 rogid:CIMZa9bvEUzZ4k7XGnaC4irMOpo559292 intact-crc:E4999CD9A76236F0|rigid:JuImQNgPv/vtgF1MJ8r8AOrLSVg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21242 uniprotkb:P21243 intact:EBI-13963|ensemblfungi:YOR362C|uniprotkb:D6W357 intact:EBI-13975|uniprotkb:P15708|ensemblfungi:YGL011C|uniprotkb:D6VUC6 psi-mi:psa7_yeast(display_long)|uniprotkb:PRE10(gene name)|psi-mi:PRE10(display_short)|uniprotkb:PRC1(gene name synonym)|uniprotkb:PRS1(gene name synonym)|uniprotkb:O6650(orf name)|uniprotkb:YOR362C(locus name)|uniprotkb:Proteasome component C1(gene name synonym)|uniprotkb:Macropain subunit C1(gene name synonym)|uniprotkb:Proteinase YSCE subunit 1(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C1(gene name synonym) psi-mi:psa1_yeast(display_long)|uniprotkb:SCL1(gene name)|psi-mi:SCL1(display_short)|uniprotkb:PRC2(gene name synonym)|uniprotkb:PRS2(gene name synonym)|uniprotkb:YGL011C(locus name)|uniprotkb:Proteasome component C7-alpha(gene name synonym)|uniprotkb:Macropain subunit C7-alpha(gene name synonym)|uniprotkb:Proteinase YSCE subunit 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex C7(gene name synonym)|uniprotkb:Proteasome component Y8(gene name synonym)|uniprotkb:SCL1 suppressor protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318530|imex:IM-14275-421 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR362C(gene)|ensemblfungi:YOR362C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR029055|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR037555|interpro:IPR001353(20S proteasome, A and B subunits)|rcsb pdb:1FNT|interpro:IPR023332|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QW6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4Y7Y|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5A5B|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5D0X|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L5E|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5L67|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6HTC|rcsb pdb:6FVW|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6FVX|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6HV4|rcsb pdb:6G8M|rcsb pdb:6HV5|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|rcsb pdb:6HW5|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-5668541|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:1G0U|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:3SDI|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QLS|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|refseq:NP_015007.1|sgd:S000005889|mint:P21242|dip:DIP-1526N sgd:S000002979|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|ensemblfungi:YGL011C(gene)|ensemblfungi:YGL011C_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034642|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y69|rcsb pdb:4Y8K|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y8L|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|refseq:NP_011504.3|mint:P21243|dip:DIP-2810N psi-mi:"MI:0469"(intact) crc64:1E51D904CF336747 crc64:5B938C862BC8D7EB figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tVLLjztJDttaRM40dHah/J06g0E559292 rogid:CIMZa9bvEUzZ4k7XGnaC4irMOpo559292 intact-crc:2247DAF2CC4BC233|rigid:gSVpaE5in2VfTavx5OvAJXrihsg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40693 uniprotkb:P21304 intact:EBI-15415|uniprotkb:D6W1H5|ensemblfungi:YNL002C intact:EBI-14328|uniprotkb:D6VYJ9|ensemblfungi:YLR196W psi-mi:rlp7_yeast(display_long)|uniprotkb:RPL7(gene name synonym)|uniprotkb:N2014(orf name)|uniprotkb:YNL002C(locus name)|uniprotkb:RLP7(gene name)|psi-mi:RLP7(display_short)|uniprotkb:Ribosomal protein L7-like(gene name synonym) psi-mi:pwp1_yeast(display_long)|uniprotkb:L8167.10(orf name)|uniprotkb:YLR196W(locus name)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318563|imex:IM-14275-424 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004947|refseq:NP_014396.3|ensemblfungi:YNL002C(gene)|ensemblfungi:YNL002C_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000465"("exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|rcsb pdb:3JCT|rcsb pdb:4V7F|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6M62|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BTB|dip:DIP-6476N|mint:P40693 refseq:NP_013297.1|sgd:S000004186|ensemblfungi:YLR196W(gene)|ensemblfungi:YLR196W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR044285|mint:P21304|dip:DIP-4203N psi-mi:"MI:0469"(intact) crc64:64714DDFAFB90B5D crc64:FC0189B289494AB5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HR8kGX5foVbBQ/nWTKMM16uB3E8559292 rogid:Q1nPXtlkpIw8JosaiYX0PSVNaSw559292 intact-crc:FEAA78F3945AF0DC|rigid:MildRPUzcXjvd0ae2Qd1ZuJsOuI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21304 uniprotkb:P24783 intact:EBI-14328|uniprotkb:D6VYJ9|ensemblfungi:YLR196W intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W psi-mi:pwp1_yeast(display_long)|uniprotkb:L8167.10(orf name)|uniprotkb:YLR196W(locus name)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short) psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318552|imex:IM-14275-423 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013297.1|sgd:S000004186|ensemblfungi:YLR196W(gene)|ensemblfungi:YLR196W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR044285|mint:P21304|dip:DIP-4203N sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) crc64:FC0189B289494AB5 crc64:30FE3D4C7E653120 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Q1nPXtlkpIw8JosaiYX0PSVNaSw559292 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 intact-crc:FA385A089CE38335|rigid:FYXdfIMOkgiVee3s4tbhafG28TY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21372 uniprotkb:P38783 intact:EBI-13824|ensemblfungi:YBR237W|uniprotkb:D6VQN3 intact:EBI-24555|uniprotkb:D3DL08|ensemblfungi:YHR059W psi-mi:prp5_yeast(display_long)|uniprotkb:PRP5(gene name)|psi-mi:PRP5(display_short)|uniprotkb:RNA5(gene name synonym)|uniprotkb:YBR237W(locus name)|uniprotkb:YBR1603(orf name) psi-mi:fyv4_yeast(display_long)|uniprotkb:FYV4(gene name)|psi-mi:FYV4(display_short)|uniprotkb:Function required for yeast viability protein 4(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS41(gene name synonym)|uniprotkb:YHR059W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318585|imex:IM-14275-426 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009796.1|sgd:S000000441|ensemblfungi:YBR237W(gene)|ensemblfungi:YBR237W_mRNA(transcript)|go:"GO:0000348"(mRNA branch site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:4LJY|rcsb pdb:4LK2|mint:P21372|dip:DIP-88N refseq:NP_011926.1|sgd:S000001101|dip:DIP-4906N|mint:P38783|ensemblfungi:YHR059W(gene)|ensemblfungi:YHR059W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR019083|interpro:IPR039603|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF psi-mi:"MI:0469"(intact) - crc64:1662DB8385D067B9 figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0aE2/P83FZO9bSFTxeCB7o5NY2w559292 rogid:bpqChwMYewyjUEHycGB2DzIGzBw559292 intact-crc:32F05B717F081CEE|rigid:VsMXf2e/u9y/W/Za1T/m4rvGnhg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21304 uniprotkb:Q08235 intact:EBI-14328|uniprotkb:D6VYJ9|ensemblfungi:YLR196W intact:EBI-3775|uniprotkb:D6W1Z1|ensemblfungi:YOL077C psi-mi:pwp1_yeast(display_long)|uniprotkb:L8167.10(orf name)|uniprotkb:YLR196W(locus name)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short) psi-mi:brx1_yeast(display_long)|uniprotkb:YOL077C(locus name)|uniprotkb:BRX1(gene name)|psi-mi:BRX1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318574|imex:IM-14275-425 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013297.1|sgd:S000004186|ensemblfungi:YLR196W(gene)|ensemblfungi:YLR196W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR044285|mint:P21304|dip:DIP-4203N refseq:NP_014565.2|sgd:S000005437|dip:DIP-6317N|mint:Q08235|ensemblfungi:YOL077C(gene)|ensemblfungi:YOL077C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000464"("endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000465"("exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR007109(Brix)|interpro:IPR026532|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5 psi-mi:"MI:0469"(intact) crc64:FC0189B289494AB5 crc64:31466853EF0E7301 figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Q1nPXtlkpIw8JosaiYX0PSVNaSw559292 rogid:mPR6HWKwM6RNCRE/vezsYlCmEGY559292 intact-crc:83E96DEBFE7D4C05|rigid:xRF6M4WgE1Rxppth+mCOxonlJ7c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21373 uniprotkb:Q12218 intact:EBI-20174|uniprotkb:Q54AD8|uniprotkb:D6VWM0|uniprotkb:E9P8Y8|ensemblfungi:YJR049C intact:EBI-32557|uniprotkb:D6W276|ensemblfungi:YOR009W psi-mi:utr1_yeast(display_long)|uniprotkb:UTR1(gene name)|psi-mi:UTR1(display_short)|uniprotkb:YJR049C(locus name)|uniprotkb:J1655(orf name)|uniprotkb:Unknown transcript 1 protein(gene name synonym) psi-mi:tir4_yeast(display_long)|uniprotkb:TIR4(gene name)|psi-mi:TIR4(display_short)|uniprotkb:UNB487(orf name)|uniprotkb:TIP1-related protein 4(gene name synonym)|uniprotkb:YOR009W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318596|imex:IM-14275-427 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012583.1|sgd:S000003810|ensemblfungi:YJR049C(gene)|ensemblfungi:YJR049C_mRNA(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0042736"(NADH kinase activity)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|reactome:R-SCE-196807|mint:P21373|dip:DIP-4479N refseq:NP_014652.1|sgd:S000005535|dip:DIP-5194N|mint:Q12218|ensemblfungi:YOR009W(gene)|ensemblfungi:YOR009W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005199"(structural constituent of cell wall)|go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0071944"(cell periphery)|interpro:IPR000992(Stress-induced protein SRP1/TIP1) psi-mi:"MI:0469"(intact) crc64:1BF4F01D7213B94B crc64:BA12415C400FAD65 figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:l/mDQcBTaLoGMxT50H2W7npbw2g559292 rogid:bZhhVELNyh7ODg1CNh1fVPrKC18559292 intact-crc:558A57CEE719A25C|rigid:WrFgC12XbnY2Lyw677eT3k1t48Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07844 uniprotkb:P21538 intact:EBI-27142|uniprotkb:D6VXX1|ensemblfungi:YLL034C intact:EBI-14905|uniprotkb:D6VQ49|ensemblfungi:YBR049C psi-mi:rix7_yeast(display_long)|uniprotkb:RIX7(gene name)|psi-mi:RIX7(display_short)|uniprotkb:YLL034C(locus name) psi-mi:reb1_yeast(display_long)|uniprotkb:REB1(gene name)|psi-mi:REB1(display_short)|uniprotkb:GRF2(gene name synonym)|uniprotkb:YBR049C(locus name)|uniprotkb:YBR0502(orf name)|uniprotkb:QBP(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318618|imex:IM-14275-429 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013066.1|sgd:S000003957|mint:Q07844|dip:DIP-6385N|ensemblfungi:YLL034C(gene)|ensemblfungi:YLL034C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990275"(preribosome binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569 refseq:NP_009605.1|sgd:S000000253|ensemblfungi:YBR049C(gene)|ensemblfungi:YBR049C_mRNA(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001174"(transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|go:"GO:0000785"(chromatin)|dip:DIP-6374N|mint:P21538 psi-mi:"MI:0469"(intact) crc64:133528B9D0987103 crc64:318EB17D20D004B6 figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CEDaCFQQsHNDc1vhyXrgiMUNzO4559292 rogid:VfwlaPZpEKGMfeaQz1Pib8UPoAQ559292 intact-crc:06E702729323DEF3|rigid:FrYNN6oI+wpqB9dKWOSfZJ6hL+c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33331 uniprotkb:P21538 intact:EBI-12287|ensemblfungi:YER009W|uniprotkb:D3DLQ6 intact:EBI-14905|uniprotkb:D6VQ49|ensemblfungi:YBR049C psi-mi:ntf2_yeast(display_long)|uniprotkb:YER009W(locus name)|uniprotkb:NTF2(gene name)|psi-mi:NTF2(display_short)|uniprotkb:Nuclear transport factor P10(gene name synonym) psi-mi:reb1_yeast(display_long)|uniprotkb:REB1(gene name)|psi-mi:REB1(display_short)|uniprotkb:GRF2(gene name synonym)|uniprotkb:YBR049C(locus name)|uniprotkb:YBR0502(orf name)|uniprotkb:QBP(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318607|imex:IM-14275-428 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER009W(gene)|ensemblfungi:YER009W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR032710|rcsb pdb:1GY7|rcsb pdb:1GYB|interpro:IPR018222|refseq:NP_010925.1|sgd:S000000811|mint:P33331|dip:DIP-2245N refseq:NP_009605.1|sgd:S000000253|ensemblfungi:YBR049C(gene)|ensemblfungi:YBR049C_mRNA(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001174"(transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|go:"GO:0000785"(chromatin)|dip:DIP-6374N|mint:P21538 psi-mi:"MI:0469"(intact) crc64:5660D8C00E634714 crc64:318EB17D20D004B6 figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mBAVfS8sOGWKdb5tkfP6RksfoTI559292 rogid:VfwlaPZpEKGMfeaQz1Pib8UPoAQ559292 intact-crc:05017CCCC21C4927|rigid:6PQmHh0tXzycfzUzdMGiixUCDfs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21691 uniprotkb:Q96VH3 intact:EBI-17211|uniprotkb:D6VXG2|ensemblfungi:YKR101W intact:EBI-2044941|uniprotkb:D6VQZ3|ensemblfungi:YCL021W-A psi-mi:sir1_yeast(display_long)|uniprotkb:SIR1(gene name)|psi-mi:SIR1(display_short)|uniprotkb:YKR101W(locus name)|uniprotkb:Silent information regulator 1(gene name synonym)|uniprotkb:Heterochromatin protein SIR1(gene name synonym) psi-mi:yc021_yeast(display_long)|uniprotkb:YCL021W-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318629|imex:IM-14275-430 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013027.4|sgd:S000001809|ensemblfungi:YKR101W(gene)|ensemblfungi:YKR101W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR021646|interpro:IPR037240|rcsb pdb:1Z1A|rcsb pdb:1ZBX|rcsb pdb:1ZHI|dip:DIP-2453N|mint:P21691 sgd:S000007549|refseq:NP_065437.1|mint:Q96VH3|ensemblfungi:YCL021W-A(gene)|ensemblfungi:YCL021W-A_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) crc64:00FEABD1BD35BC81 - figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CMVYYG4cMH7Z2Gmq21uNeDyFqqU559292 rogid:KPtxCFX4m13AghkJuoOkuTMuIWA559292 intact-crc:36B2A837E34B3C32|rigid:8EeQNg813IZWAoxjbS+CNzhPiZQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10964 uniprotkb:P22138 intact:EBI-15730|uniprotkb:Q99330|uniprotkb:D6W336|ensemblfungi:YOR341W intact:EBI-15736|uniprotkb:D6W421|ensemblfungi:YPR010C psi-mi:rpa1_yeast(display_long)|uniprotkb:RPA190(gene name)|psi-mi:RPA190(display_short)|uniprotkb:RPA1(gene name synonym)|uniprotkb:RRN1(gene name synonym)|uniprotkb:YOR341W(locus name)|uniprotkb:O6276(orf name)|uniprotkb:DNA-directed RNA polymerase I 190 kDa polypeptide(gene name synonym)|uniprotkb:DNA-directed RNA polymerase I largest subunit(gene name synonym) psi-mi:rpa2_yeast(display_long)|uniprotkb:RPA135(gene name)|psi-mi:RPA135(display_short)|uniprotkb:RPA2(gene name synonym)|uniprotkb:RRN2(gene name synonym)|uniprotkb:SRP3(gene name synonym)|uniprotkb:YPR010C(locus name)|uniprotkb:YP9531.03C(orf name)|uniprotkb:DNA-directed RNA polymerase I polypeptide 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase I 135 kDa polypeptide(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318651|imex:IM-14275-432 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005868|refseq:NP_014986.3|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR015699(DNA-directed RNA pol I, largest subunit)|interpro:IPR038120|interpro:IPR042102|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|ensemblfungi:YOR341W(gene)|ensemblfungi:YOR341W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0008270"(zinc ion binding)|dip:DIP-999N|mint:P10964 refseq:NP_015335.1|sgd:S000006214|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5M5X|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772|ensemblfungi:YPR010C(gene)|ensemblfungi:YPR010C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR009674(RNA polymerase I, Rpa2 specific)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|dip:DIP-135N|mint:P22138 psi-mi:"MI:0469"(intact) crc64:DF65A7AA459D5E6D crc64:72FA95B66F98C5F8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:krXuLY5fTE34McW4bnuPqns5Oy4559292 rogid:9uVcBIikY0xLsnYo9ZZaqfLX2u8559292 intact-crc:D958E5F88C3C91CA|rigid:gOJQOPunVUZsZqtBjJMBl9OnQMI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21965 uniprotkb:Q12462 intact:EBI-10517|ensemblfungi:YNL307C|uniprotkb:D6W0N8 intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C psi-mi:mck1_yeast(display_long)|uniprotkb:YPK1(gene name synonym)|uniprotkb:YNL307C(locus name)|uniprotkb:N0392(orf name)|uniprotkb:MCK1(gene name)|psi-mi:MCK1(display_short)|uniprotkb:Meiosis and centromere regulatory kinase(gene name synonym) psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318640|imex:IM-14275-431 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014092.1|sgd:S000005251|ensemblfungi:YNL307C(gene)|ensemblfungi:YNL307C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030332"(cyclin binding)|go:"GO:0030437"(ascospore formation)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|reactome:R-SCE-3371453|go:"GO:0034605"(cellular response to heat)|mint:P21965|dip:DIP-5860N refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) psi-mi:"MI:0469"(intact) crc64:BCF0C776B6E3841B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:smRz/MIn0un4L+VS7nVGNMe0/0E559292 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 intact-crc:918FEEDFC0FA44DB|rigid:3VOnagC8Ui1rIGlQeKpSo01BPOI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22138 uniprotkb:P20434 intact:EBI-15736|uniprotkb:D6W421|ensemblfungi:YPR010C intact:EBI-15781|uniprotkb:Q02121|ensemblfungi:YBR154C|uniprotkb:D6VQE9 psi-mi:rpa2_yeast(display_long)|uniprotkb:RPA135(gene name)|psi-mi:RPA135(display_short)|uniprotkb:RPA2(gene name synonym)|uniprotkb:RRN2(gene name synonym)|uniprotkb:SRP3(gene name synonym)|uniprotkb:YPR010C(locus name)|uniprotkb:YP9531.03C(orf name)|uniprotkb:DNA-directed RNA polymerase I polypeptide 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase I 135 kDa polypeptide(gene name synonym) psi-mi:rpab1_yeast(display_long)|uniprotkb:RPB5(gene name)|psi-mi:RPB5(display_short)|uniprotkb:YBR154C(locus name)|uniprotkb:YBR1204(orf name)|uniprotkb:RPA7(gene name synonym)|uniprotkb:RPC9(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide(gene name synonym)|uniprotkb:ABC27(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318662|imex:IM-14275-433 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015335.1|sgd:S000006214|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5M5X|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772|ensemblfungi:YPR010C(gene)|ensemblfungi:YPR010C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR009674(RNA polymerase I, Rpa2 specific)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|dip:DIP-135N|mint:P22138 rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|rcsb pdb:1WCM|rcsb pdb:1Y1V|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|rcsb pdb:2B63|rcsb pdb:2B8K|interpro:IPR020608|interpro:IPR020609|rcsb pdb:2E2H|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:1DZF|rcsb pdb:1I3Q|rcsb pdb:2E2I|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:5M5Y|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6H67|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:2E2J|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|ensemblfungi:YBR154C(gene)|ensemblfungi:YBR154C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4V1M|rcsb pdb:2JA5|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2JA6|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:2JA7|rcsb pdb:3GTG|rcsb pdb:2JA8|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:2NVQ|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4YM7|rcsb pdb:5C3E|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5G5L|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6H68|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|rcsb pdb:6UQ2|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-77075|reactome:R-SCE-9018519|refseq:NP_009712.1|sgd:S000000358|dip:DIP-71N|mint:P20434 psi-mi:"MI:0469"(intact) crc64:72FA95B66F98C5F8 crc64:2A15F7114D69D829 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9uVcBIikY0xLsnYo9ZZaqfLX2u8559292 rogid:j/jAJ2fXWf4ebK1aWTWrKERGUpM559292 intact-crc:29520BC93947AD6D|rigid:OJ7AkqNLGs/SGezuGklmvx9/Qlc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:P22140 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-6494|uniprotkb:D3DL73|ensemblfungi:YHR123W psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:ept1_yeast(display_long)|uniprotkb:EPT1(gene name)|psi-mi:EPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase EPT1(gene name synonym)|uniprotkb:YHR123W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318684|imex:IM-14275-435 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 refseq:NP_011991.1|sgd:S000001165|mint:P22140|dip:DIP-5619N|ensemblfungi:YHR123W(gene)|ensemblfungi:YHR123W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0004307"(ethanolaminephosphotransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213|interpro:IPR014472(Choline/ethanolaminephosphotransferase) psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 - figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:CWeN5fKw1tHLle/Vgn+jmL/zrQk559292 intact-crc:8B03D2E02728B5E2|rigid:iHmlBJxJZ81egMc3oHb3JIYR+Ts false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P22140 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-6494|uniprotkb:D3DL73|ensemblfungi:YHR123W psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:ept1_yeast(display_long)|uniprotkb:EPT1(gene name)|psi-mi:EPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase EPT1(gene name synonym)|uniprotkb:YHR123W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318673|imex:IM-14275-434 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_011991.1|sgd:S000001165|mint:P22140|dip:DIP-5619N|ensemblfungi:YHR123W(gene)|ensemblfungi:YHR123W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0004307"(ethanolaminephosphotransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213|interpro:IPR014472(Choline/ethanolaminephosphotransferase) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:CWeN5fKw1tHLle/Vgn+jmL/zrQk559292 intact-crc:61DDD8E84FDF1B9F|rigid:raUgWBhlheiAmf6PBlJFqXnTJqM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22140 uniprotkb:P25361 intact:EBI-6494|uniprotkb:D3DL73|ensemblfungi:YHR123W intact:EBI-21909|uniprotkb:D6VR52|ensemblfungi:YCR043C psi-mi:ept1_yeast(display_long)|uniprotkb:EPT1(gene name)|psi-mi:EPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase EPT1(gene name synonym)|uniprotkb:YHR123W(locus name) psi-mi:yct3_yeast(display_long)|uniprotkb:YCR43C(orf name)|uniprotkb:YCR725(orf name)|uniprotkb:YCR043C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318706|imex:IM-14275-437 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011991.1|sgd:S000001165|mint:P22140|dip:DIP-5619N|ensemblfungi:YHR123W(gene)|ensemblfungi:YHR123W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0004307"(ethanolaminephosphotransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213|interpro:IPR014472(Choline/ethanolaminephosphotransferase) sgd:S000000639|refseq:NP_009972.1|mint:P25361|ensemblfungi:YCR043C(gene)|ensemblfungi:YCR043C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0043332"(mating projection tip) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CWeN5fKw1tHLle/Vgn+jmL/zrQk559292 rogid:bEMtsAa5vCsWqGOiXwBK40Pa0xQ559292 intact-crc:28D5CCFD4071E502|rigid:8Zq+QxWbcRIN+hGfbSmev45+9Ew false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17898 uniprotkb:P22140 intact:EBI-2050738|uniprotkb:D6W152|ensemblfungi:YNL130C intact:EBI-6494|uniprotkb:D3DL73|ensemblfungi:YHR123W psi-mi:cpt1_yeast(display_long)|uniprotkb:Diacylglycerol cholinephosphotransferase 1(gene name synonym)|uniprotkb:Sn-1,2-diacylglycerol cholinephosphotransferase(gene name synonym)|uniprotkb:N1218(orf name)|uniprotkb:N1867(orf name)|uniprotkb:YNL130C(locus name)|uniprotkb:CPT1(gene name)|psi-mi:CPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase CPT1(gene name synonym) psi-mi:ept1_yeast(display_long)|uniprotkb:EPT1(gene name)|psi-mi:EPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase EPT1(gene name synonym)|uniprotkb:YHR123W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318695|imex:IM-14275-436 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005074|refseq:NP_014269.4|dip:DIP-7848N|mint:P17898|ensemblfungi:YNL130C(gene)|ensemblfungi:YNL130C_mRNA(transcript)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006657"(CDP-choline pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213 refseq:NP_011991.1|sgd:S000001165|mint:P22140|dip:DIP-5619N|ensemblfungi:YHR123W(gene)|ensemblfungi:YHR123W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0004307"(ethanolaminephosphotransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213|interpro:IPR014472(Choline/ethanolaminephosphotransferase) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:PsU8UELFPsbtbzOS6oBnXJAuk/A559292 rogid:CWeN5fKw1tHLle/Vgn+jmL/zrQk559292 intact-crc:E6367B487DB00FAE|rigid:cfvCSbgRZoDpyqKmb4ZXoIbaCsc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:P22140 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-6494|uniprotkb:D3DL73|ensemblfungi:YHR123W psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:ept1_yeast(display_long)|uniprotkb:EPT1(gene name)|psi-mi:EPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase EPT1(gene name synonym)|uniprotkb:YHR123W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318728|imex:IM-14275-439 author score:99.26 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_011991.1|sgd:S000001165|mint:P22140|dip:DIP-5619N|ensemblfungi:YHR123W(gene)|ensemblfungi:YHR123W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0004307"(ethanolaminephosphotransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213|interpro:IPR014472(Choline/ethanolaminephosphotransferase) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.26|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:CWeN5fKw1tHLle/Vgn+jmL/zrQk559292 intact-crc:06B66CACEB90A400|rigid:DEEy9ohPLreTMiqMcRzfK+7rj5g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:P22140 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-6494|uniprotkb:D3DL73|ensemblfungi:YHR123W psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:ept1_yeast(display_long)|uniprotkb:EPT1(gene name)|psi-mi:EPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase EPT1(gene name synonym)|uniprotkb:YHR123W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318717|imex:IM-14275-438 author score:99.32 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_011991.1|sgd:S000001165|mint:P22140|dip:DIP-5619N|ensemblfungi:YHR123W(gene)|ensemblfungi:YHR123W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0004307"(ethanolaminephosphotransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213|interpro:IPR014472(Choline/ethanolaminephosphotransferase) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.32|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:CWeN5fKw1tHLle/Vgn+jmL/zrQk559292 intact-crc:1C29B934418553B6|rigid:HL6ePycsGQkUk8XrOwZh1uzlI00 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39719 uniprotkb:P22146 intact:EBI-20703|uniprotkb:Q05165|uniprotkb:D6VPG5|ensemblfungi:YAL053W intact:EBI-7327|uniprotkb:P23151|uniprotkb:D6W0D4|ensemblfungi:YMR307W psi-mi:flc2_yeast(display_long)|uniprotkb:YAL053W(locus name)|uniprotkb:FLC2(gene name)|psi-mi:FLC2(display_short)|uniprotkb:FAD transporter 2(gene name synonym)|uniprotkb:TRP-like ion channel FLC2(gene name synonym) psi-mi:gas1_yeast(display_long)|uniprotkb:GAS1(gene name)|psi-mi:GAS1(display_short)|uniprotkb:GGP1(gene name synonym)|uniprotkb:YMR307W(locus name)|uniprotkb:YM9952.09(orf name)|uniprotkb:Glycoprotein GP115(gene name synonym)|uniprotkb:Glycolipid-anchored surface protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318750|imex:IM-14275-441 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009348.2|sgd:S000000049|ensemblfungi:YAL053W(gene)|ensemblfungi:YAL053W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241|go:"GO:0055085"(transmembrane transport)|dip:DIP-6708N|mint:P39719 refseq:NP_014038.1|sgd:S000004924|mint:P22146|dip:DIP-4390N|ensemblfungi:YMR307W(gene)|ensemblfungi:YMR307W_mRNA(transcript)|go:"GO:0000936"(primary cell septum)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005621"(cellular bud scar)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006342"|go:"GO:0007568"(aging)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030447"(filamentous growth)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034411"("cell wall (1->3)-beta-D-glucan biosynthetic process")|go:"GO:0042124"(1,3-beta-glucanosyltransferase activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071970"("fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process")|go:"GO:1905897"(regulation of response to endoplasmic reticulum stress)|interpro:IPR004886(Glycolipid anchored surface protein GAS1)|interpro:IPR012946(X8)|interpro:IPR017853(Glycoside hydrolase, catalytic core) psi-mi:"MI:0469"(intact) - crc64:D6E39568DCB4C5AE figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:NOmMW54DNa0o7vM945DlZgVUy44559292 rogid:xdhWIDQTiYrW+VOcQpC37njMAZQ559292 intact-crc:1A2873A0454BBEFD|rigid:nI7b+lMk2RsFIJxaMw4s4K9O2JY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22140 uniprotkb:Q12270 intact:EBI-6494|uniprotkb:D3DL73|ensemblfungi:YHR123W intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:ept1_yeast(display_long)|uniprotkb:EPT1(gene name)|psi-mi:EPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase EPT1(gene name synonym)|uniprotkb:YHR123W(locus name) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318739|imex:IM-14275-440 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011991.1|sgd:S000001165|mint:P22140|dip:DIP-5619N|ensemblfungi:YHR123W(gene)|ensemblfungi:YHR123W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0004307"(ethanolaminephosphotransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213|interpro:IPR014472(Choline/ethanolaminephosphotransferase) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CWeN5fKw1tHLle/Vgn+jmL/zrQk559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:66FFB9BBD6233C64|rigid:te9xTgj5sbFxs0gYlOZkoUN0ybc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22213 uniprotkb:P14359 intact:EBI-17387|uniprotkb:D6VSH2|ensemblfungi:YDR189W intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:sly1_yeast(display_long)|uniprotkb:SLY1(gene name)|psi-mi:SLY1(display_short)|uniprotkb:YDR189W(locus name)|uniprotkb:YD9395.22(orf name)|uniprotkb:YD9346.01(orf name)|uniprotkb:Suppressor of loss of YPT1 protein 1(gene name synonym) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318761|imex:IM-14275-442 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010475.1|sgd:S000002597|ensemblfungi:YDR189W(gene)|ensemblfungi:YDR189W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0035543"(positive regulation of SNARE complex assembly)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|rcsb pdb:1MQS|reactome:R-SCE-204005|reactome:R-SCE-8980692|mint:P22213|dip:DIP-2940N refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) crc64:79B0A1C4FB45042F crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wymTcFMVeTdrOMFsga2RxUW7l30559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:E6E677A9321B3508|rigid:k0rvFtLYtUpV9nf2EN4G6rYD13s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22213 uniprotkb:P32465 intact:EBI-17387|uniprotkb:D6VSH2|ensemblfungi:YDR189W intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 psi-mi:sly1_yeast(display_long)|uniprotkb:SLY1(gene name)|psi-mi:SLY1(display_short)|uniprotkb:YDR189W(locus name)|uniprotkb:YD9395.22(orf name)|uniprotkb:YD9346.01(orf name)|uniprotkb:Suppressor of loss of YPT1 protein 1(gene name synonym) psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318772|imex:IM-14275-443 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010475.1|sgd:S000002597|ensemblfungi:YDR189W(gene)|ensemblfungi:YDR189W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0035543"(positive regulation of SNARE complex assembly)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|rcsb pdb:1MQS|reactome:R-SCE-204005|reactome:R-SCE-8980692|mint:P22213|dip:DIP-2940N ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N psi-mi:"MI:0469"(intact) crc64:79B0A1C4FB45042F - figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wymTcFMVeTdrOMFsga2RxUW7l30559292 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 intact-crc:478CE7E847156CF6|rigid:VNKGuIMtjNrBcurOFJtrjlS4JQM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03860 uniprotkb:P22213 intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W intact:EBI-17387|uniprotkb:D6VSH2|ensemblfungi:YDR189W psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:sly1_yeast(display_long)|uniprotkb:SLY1(gene name)|psi-mi:SLY1(display_short)|uniprotkb:YDR189W(locus name)|uniprotkb:YD9395.22(orf name)|uniprotkb:YD9346.01(orf name)|uniprotkb:Suppressor of loss of YPT1 protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318794|imex:IM-14275-445 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) refseq:NP_010475.1|sgd:S000002597|ensemblfungi:YDR189W(gene)|ensemblfungi:YDR189W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0035543"(positive regulation of SNARE complex assembly)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|rcsb pdb:1MQS|reactome:R-SCE-204005|reactome:R-SCE-8980692|mint:P22213|dip:DIP-2940N psi-mi:"MI:0469"(intact) crc64:395F700FBB14C569 crc64:79B0A1C4FB45042F figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 rogid:wymTcFMVeTdrOMFsga2RxUW7l30559292 intact-crc:5F0B7C69880671C6|rigid:aWKzVSQQNURB11FLJMyRvF2Y2lM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40094 uniprotkb:P22213 intact:EBI-16605|ensemblfungi:YER157W|uniprotkb:D3DM64 intact:EBI-17387|uniprotkb:D6VSH2|ensemblfungi:YDR189W psi-mi:cog3_yeast(display_long)|uniprotkb:COG3(gene name)|psi-mi:COG3(display_short)|uniprotkb:GRD20(gene name synonym)|uniprotkb:SEC34(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 3(gene name synonym)|uniprotkb:Protein SEC34(gene name synonym)|uniprotkb:YER157W(locus name) psi-mi:sly1_yeast(display_long)|uniprotkb:SLY1(gene name)|psi-mi:SLY1(display_short)|uniprotkb:YDR189W(locus name)|uniprotkb:YD9395.22(orf name)|uniprotkb:YD9346.01(orf name)|uniprotkb:Suppressor of loss of YPT1 protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318783|imex:IM-14275-444 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER157W(gene)|ensemblfungi:YER157W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR007265(Sec34-like protein)|refseq:NP_011084.1|sgd:S000000959|dip:DIP-4728N|mint:P40094 refseq:NP_010475.1|sgd:S000002597|ensemblfungi:YDR189W(gene)|ensemblfungi:YDR189W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0035543"(positive regulation of SNARE complex assembly)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|rcsb pdb:1MQS|reactome:R-SCE-204005|reactome:R-SCE-8980692|mint:P22213|dip:DIP-2940N psi-mi:"MI:0469"(intact) crc64:C7AFBE99010FE571 crc64:79B0A1C4FB45042F figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R2r0ZW+nxrykdTHq1cJy9zOmvHo559292 rogid:wymTcFMVeTdrOMFsga2RxUW7l30559292 intact-crc:83EE6AFB6196B7A3|rigid:jZel/FQlSyktNITi4+dVHmAyw9g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04410 uniprotkb:P22213 intact:EBI-32083|uniprotkb:D6VTD8|ensemblfungi:YDR517W intact:EBI-17387|uniprotkb:D6VSH2|ensemblfungi:YDR189W psi-mi:grh1_yeast(display_long)|uniprotkb:GRH1(gene name)|psi-mi:GRH1(display_short)|uniprotkb:YDR517W(locus name) psi-mi:sly1_yeast(display_long)|uniprotkb:SLY1(gene name)|psi-mi:SLY1(display_short)|uniprotkb:YDR189W(locus name)|uniprotkb:YD9395.22(orf name)|uniprotkb:YD9346.01(orf name)|uniprotkb:Suppressor of loss of YPT1 protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318805|imex:IM-14275-446 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010805.1|sgd:S000002925|dip:DIP-6613N|mint:Q04410|ensemblfungi:YDR517W(gene)|ensemblfungi:YDR517W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0009306"(protein secretion)|go:"GO:0031090"(organelle membrane)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR007583(GRASP55/65)|interpro:IPR024958|interpro:IPR036034|rcsb pdb:6G8Y|reactome:R-SCE-162658|reactome:R-SCE-204005 refseq:NP_010475.1|sgd:S000002597|ensemblfungi:YDR189W(gene)|ensemblfungi:YDR189W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0035543"(positive regulation of SNARE complex assembly)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|rcsb pdb:1MQS|reactome:R-SCE-204005|reactome:R-SCE-8980692|mint:P22213|dip:DIP-2940N psi-mi:"MI:0469"(intact) crc64:A7CE62DFE4631214 crc64:79B0A1C4FB45042F figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Tj4Jf1BeT57ROzFoNoi+g9GLuYk559292 rogid:wymTcFMVeTdrOMFsga2RxUW7l30559292 intact-crc:D06666EA2067F6D7|rigid:lizDZgmLiD33d2IkPHIpTa2Rklw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06096 uniprotkb:P22213 intact:EBI-4823|uniprotkb:D6W4A3|ensemblfungi:YPR105C intact:EBI-17387|uniprotkb:D6VSH2|ensemblfungi:YDR189W psi-mi:cog4_yeast(display_long)|uniprotkb:COG4(gene name)|psi-mi:COG4(display_short)|uniprotkb:SEC38(gene name synonym)|uniprotkb:YPR105C(locus name)|uniprotkb:P8283.16(orf name)|uniprotkb:SGF1(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 4(gene name synonym)|uniprotkb:Protein SEC38(gene name synonym) psi-mi:sly1_yeast(display_long)|uniprotkb:SLY1(gene name)|psi-mi:SLY1(display_short)|uniprotkb:YDR189W(locus name)|uniprotkb:YD9395.22(orf name)|uniprotkb:YD9346.01(orf name)|uniprotkb:Suppressor of loss of YPT1 protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318816|imex:IM-14275-447 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015430.1|sgd:S000006309|dip:DIP-2003N|mint:Q06096|ensemblfungi:YPR105C(gene)|ensemblfungi:YPR105C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0005829"(cytosol)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|interpro:IPR013167(COG4 transport) refseq:NP_010475.1|sgd:S000002597|ensemblfungi:YDR189W(gene)|ensemblfungi:YDR189W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0035543"(positive regulation of SNARE complex assembly)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|rcsb pdb:1MQS|reactome:R-SCE-204005|reactome:R-SCE-8980692|mint:P22213|dip:DIP-2940N psi-mi:"MI:0469"(intact) crc64:22F265AB2AD91533 crc64:79B0A1C4FB45042F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZsM2iBiMekDXsSPQKbfiWoVXnMU559292 rogid:wymTcFMVeTdrOMFsga2RxUW7l30559292 intact-crc:D9313B5C93FF4A45|rigid:zFz/TqEoHzMGnT1MwWd0YPnxaok false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23201 uniprotkb:P23201 intact:EBI-17803|uniprotkb:D6VXY3|ensemblfungi:YLL021W intact:EBI-17803|uniprotkb:D6VXY3|ensemblfungi:YLL021W psi-mi:spa2_yeast(display_long)|uniprotkb:SPA2(gene name)|psi-mi:SPA2(display_short)|uniprotkb:PEA1(gene name synonym)|uniprotkb:YLL021W(locus name)|uniprotkb:L1209(orf name) psi-mi:spa2_yeast(display_long)|uniprotkb:SPA2(gene name)|psi-mi:SPA2(display_short)|uniprotkb:PEA1(gene name synonym)|uniprotkb:YLL021W(locus name)|uniprotkb:L1209(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318838|imex:IM-14275-449 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013079.1|sgd:S000003944|ensemblfungi:YLL021W(gene)|ensemblfungi:YLL021W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000133"(polarisome)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031382"(mating projection formation)|go:"GO:0031384"(regulation of initiation of mating projection growth)|go:"GO:0031385"(regulation of termination of mating projection growth)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0036267"(invasive filamentous growth)|go:"GO:0043332"(mating projection tip)|go:"GO:1902716"(cell cortex of growing cell tip)|go:"GO:1903827"|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR013724("Spa2 homology (SHD) of GIT")|interpro:IPR039892|mint:P23201|dip:DIP-99N refseq:NP_013079.1|sgd:S000003944|ensemblfungi:YLL021W(gene)|ensemblfungi:YLL021W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000133"(polarisome)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031382"(mating projection formation)|go:"GO:0031384"(regulation of initiation of mating projection growth)|go:"GO:0031385"(regulation of termination of mating projection growth)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0036267"(invasive filamentous growth)|go:"GO:0043332"(mating projection tip)|go:"GO:1902716"(cell cortex of growing cell tip)|go:"GO:1903827"|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR013724("Spa2 homology (SHD) of GIT")|interpro:IPR039892|mint:P23201|dip:DIP-99N psi-mi:"MI:0469"(intact) crc64:2EBB616152382C89 crc64:2EBB616152382C89 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oRildAaA55yGWhSLQ9Zn3Wfndkg559292 rogid:oRildAaA55yGWhSLQ9Zn3Wfndkg559292 intact-crc:438DAEDAA63090FB|rigid:K3ae4rh68Wwnv7InlFYN4WZxZI4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:P22213 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-17387|uniprotkb:D6VSH2|ensemblfungi:YDR189W psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:sly1_yeast(display_long)|uniprotkb:SLY1(gene name)|psi-mi:SLY1(display_short)|uniprotkb:YDR189W(locus name)|uniprotkb:YD9395.22(orf name)|uniprotkb:YD9346.01(orf name)|uniprotkb:Suppressor of loss of YPT1 protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318827|imex:IM-14275-448 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 refseq:NP_010475.1|sgd:S000002597|ensemblfungi:YDR189W(gene)|ensemblfungi:YDR189W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0035543"(positive regulation of SNARE complex assembly)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|rcsb pdb:1MQS|reactome:R-SCE-204005|reactome:R-SCE-8980692|mint:P22213|dip:DIP-2940N psi-mi:"MI:0469"(intact) - crc64:79B0A1C4FB45042F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:wymTcFMVeTdrOMFsga2RxUW7l30559292 intact-crc:E42B1AB607ECCCD1|rigid:zU1xxVlhGkAjU5fridrTn12EgvE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39010 uniprotkb:P23291 intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C intact:EBI-4718|uniprotkb:E9P958|uniprotkb:D3DL84|ensemblfungi:YHR135C psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:kc11_yeast(display_long)|uniprotkb:YCK1(gene name)|psi-mi:YCK1(display_short)|uniprotkb:CKI2(gene name synonym)|uniprotkb:YHR135C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318860|imex:IM-14275-451 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 refseq:NP_012003.1|sgd:S000001177|dip:DIP-719N|mint:P23291|ensemblfungi:YHR135C(gene)|ensemblfungi:YHR135C_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0009749"(response to glucose)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:5X18 psi-mi:"MI:0469"(intact) - crc64:77344717818C2D17 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 rogid:pFpwRNbvvNZ1NPc7VMVXSivwMeI559292 intact-crc:74CB3646770DB201|rigid:81B90tsG/lHKIUZWSRS68Mz1tp4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23201 uniprotkb:P38853 intact:EBI-17803|uniprotkb:D6VXY3|ensemblfungi:YLL021W intact:EBI-9619|ensemblfungi:YHR158C|uniprotkb:D3DLA7|uniprotkb:E9P8X4 psi-mi:spa2_yeast(display_long)|uniprotkb:SPA2(gene name)|psi-mi:SPA2(display_short)|uniprotkb:PEA1(gene name synonym)|uniprotkb:YLL021W(locus name)|uniprotkb:L1209(orf name) psi-mi:kel1_yeast(display_long)|uniprotkb:KEL1(gene name)|psi-mi:KEL1(display_short)|uniprotkb:YHR158C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318849|imex:IM-14275-450 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013079.1|sgd:S000003944|ensemblfungi:YLL021W(gene)|ensemblfungi:YLL021W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000133"(polarisome)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031382"(mating projection formation)|go:"GO:0031384"(regulation of initiation of mating projection growth)|go:"GO:0031385"(regulation of termination of mating projection growth)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0036267"(invasive filamentous growth)|go:"GO:0043332"(mating projection tip)|go:"GO:1902716"(cell cortex of growing cell tip)|go:"GO:1903827"|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR013724("Spa2 homology (SHD) of GIT")|interpro:IPR039892|mint:P23201|dip:DIP-99N ensemblfungi:YHR158C(gene)|ensemblfungi:YHR158C_mRNA(transcript)|go:"GO:0000755"(cytogamy)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090337"(regulation of formin-nucleated actin cable assembly)|go:"GO:1990615"(Kelch-containing formin regulatory complex)|interpro:IPR015915(Kelch-type beta propeller)|refseq:NP_012028.1|sgd:S000001201|dip:DIP-1403N|mint:P38853 psi-mi:"MI:0469"(intact) crc64:2EBB616152382C89 crc64:43D0FC570F1D5E4D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oRildAaA55yGWhSLQ9Zn3Wfndkg559292 rogid:pdHtsxpdf1r7G2K9e9EPHajJS3w559292 intact-crc:6022614740EA3D58|rigid:iR9DS59nb/1JrRbV+CmrPXJKYnk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23561 uniprotkb:P23202 intact:EBI-18259|uniprotkb:D6VZ00|ensemblfungi:YLR362W intact:EBI-20138|uniprotkb:D6W0W3|ensemblfungi:YNL229C psi-mi:ste11_yeast(display_long)|uniprotkb:STE11(gene name)|psi-mi:STE11(display_short)|uniprotkb:L8039.10(orf name)|uniprotkb:YLR362W(locus name) psi-mi:ure2_yeast(display_long)|uniprotkb:URE2(gene name)|psi-mi:URE2(display_short)|uniprotkb:Disulfide reductase(gene name synonym)|uniprotkb:Glutathione peroxidase(gene name synonym)|uniprotkb:N1165(orf name)|uniprotkb:YNL229C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318871|imex:IM-14275-452 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013466.1|sgd:S000004354|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035405"(histone-threonine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029458|rcsb pdb:1OW5|rcsb pdb:1X9X|reactome:R-SCE-2559580|ensemblfungi:YLR362W(gene)|ensemblfungi:YLR362W_mRNA(transcript)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|dip:DIP-861N|mint:P23561 refseq:NP_014170.1|sgd:S000005173|ensemblfungi:YNL229C(gene)|ensemblfungi:YNL229C_mRNA(transcript)|mint:P23202|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0010044"(response to aluminum ion)|go:"GO:0032447"(protein urmylation)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR017298(Prion URE2)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:1G6W|rcsb pdb:1G6Y|rcsb pdb:1HQO|rcsb pdb:1JZR|rcsb pdb:1K0A|rcsb pdb:1K0B|rcsb pdb:1K0C|rcsb pdb:1K0D|go:"GO:0003714"(transcription corepressor activity)|dip:DIP-1308N psi-mi:"MI:0469"(intact) crc64:E9E0DF27114EEEEF crc64:2C628976034B0F1C figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:KhdnSv61wKSQuH5bBkQS9yVxLns559292 rogid:jjsWygBsEp8axNurMa3pxPMQJ2k559292 intact-crc:9A3B595A92D9CCBB|rigid:BaUkI/u5bOC+0jzjS6FCA0W6Jkk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23638 uniprotkb:P23639 intact:EBI-13967|ensemblfungi:YGR135W|uniprotkb:D6VUR7 intact:EBI-13959|ensemblfungi:YML092C|uniprotkb:D6W0J3 psi-mi:psa3_yeast(display_long)|uniprotkb:PRE9(gene name)|psi-mi:PRE9(display_short)|uniprotkb:YGR135W(locus name)|uniprotkb:PRS5(gene name synonym)|uniprotkb:Proteasome component Y13(gene name synonym)|uniprotkb:Macropain subunit Y13(gene name synonym)|uniprotkb:Proteinase YSCE subunit 13(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit Y13(gene name synonym) psi-mi:psa2_yeast(display_long)|uniprotkb:PRE8(gene name)|psi-mi:PRE8(display_short)|uniprotkb:PRS4(gene name synonym)|uniprotkb:YML092C(locus name)|uniprotkb:Proteasome component Y7(gene name synonym)|uniprotkb:Macropain subunit Y7(gene name synonym)|uniprotkb:Proteinase YSCE subunit 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit Y7(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318893|imex:IM-14275-454 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003367|ensemblfungi:YGR135W(gene)|ensemblfungi:YGR135W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0080129"(proteasome core complex assembly)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:3OKJ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NO1|rcsb pdb:4NNN|rcsb pdb:4NO6|rcsb pdb:4NNW|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|rcsb pdb:6J2Q|interpro:IPR001353(20S proteasome, A and B subunits)|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QVL|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|reactome:R-SCE-983168|reactome:R-SCE-8948751|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4QZ2|rcsb pdb:4Y70|rcsb pdb:4Y8H|rcsb pdb:4Y74|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y75|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y8R|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:4YA3|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:3OEV|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5FGF|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L60|rcsb pdb:5L5Z|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|refseq:NP_011651.3|mint:P23638|dip:DIP-2823N rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:2ZCY|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:3OEV|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4INU|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5CZ5|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5JHR|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QV4|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:5MPC|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6EF3|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWF|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HVY|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-983168|reactome:R-SCE-8948751|ensemblfungi:YML092C(gene)|ensemblfungi:YML092C_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|refseq:NP_013618.1|sgd:S000004557|mint:P23639|dip:DIP-2822N psi-mi:"MI:0469"(intact) crc64:B43BB05233A01A9E crc64:12D7DFB1AA10E9FE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5F6HrO7MputR68OA/1SAdFfJa4g559292 rogid:HiJr+UwwGu+wQImwgq3TiHYELx8559292 intact-crc:123F3C0B8A69F8FD|rigid:KKJ4FYRPpCHIrLH2k2DYedHZaLc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21242 uniprotkb:P23639 intact:EBI-13963|ensemblfungi:YOR362C|uniprotkb:D6W357 intact:EBI-13959|ensemblfungi:YML092C|uniprotkb:D6W0J3 psi-mi:psa7_yeast(display_long)|uniprotkb:PRE10(gene name)|psi-mi:PRE10(display_short)|uniprotkb:PRC1(gene name synonym)|uniprotkb:PRS1(gene name synonym)|uniprotkb:O6650(orf name)|uniprotkb:YOR362C(locus name)|uniprotkb:Proteasome component C1(gene name synonym)|uniprotkb:Macropain subunit C1(gene name synonym)|uniprotkb:Proteinase YSCE subunit 1(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C1(gene name synonym) psi-mi:psa2_yeast(display_long)|uniprotkb:PRE8(gene name)|psi-mi:PRE8(display_short)|uniprotkb:PRS4(gene name synonym)|uniprotkb:YML092C(locus name)|uniprotkb:Proteasome component Y7(gene name synonym)|uniprotkb:Macropain subunit Y7(gene name synonym)|uniprotkb:Proteinase YSCE subunit 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit Y7(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318882|imex:IM-14275-453 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR362C(gene)|ensemblfungi:YOR362C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR029055|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR037555|interpro:IPR001353(20S proteasome, A and B subunits)|rcsb pdb:1FNT|interpro:IPR023332|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QW6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4Y7Y|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5A5B|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5D0X|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L5E|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5L67|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6HTC|rcsb pdb:6FVW|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6FVX|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6HV4|rcsb pdb:6G8M|rcsb pdb:6HV5|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|rcsb pdb:6HW5|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-5668541|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:1G0U|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:3SDI|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QLS|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|refseq:NP_015007.1|sgd:S000005889|mint:P21242|dip:DIP-1526N rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:2ZCY|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:3OEV|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4INU|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5CZ5|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5JHR|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QV4|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:5MPC|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6EF3|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWF|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HVY|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-983168|reactome:R-SCE-8948751|ensemblfungi:YML092C(gene)|ensemblfungi:YML092C_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|refseq:NP_013618.1|sgd:S000004557|mint:P23639|dip:DIP-2822N psi-mi:"MI:0469"(intact) crc64:1E51D904CF336747 crc64:12D7DFB1AA10E9FE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tVLLjztJDttaRM40dHah/J06g0E559292 rogid:HiJr+UwwGu+wQImwgq3TiHYELx8559292 intact-crc:645866E504769A3C|rigid:4Ly+rNvN3Ju+/5lLYBPnixwr/VE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:P23900 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-7074|uniprotkb:D6VXW3|ensemblfungi:YLL043W psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:fps1_yeast(display_long)|uniprotkb:YLL043W(locus name)|uniprotkb:FPS1(gene name)|psi-mi:FPS1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318915|imex:IM-14275-456 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N refseq:NP_013057.1|sgd:S000003966|dip:DIP-3979N|mint:P23900|ensemblfungi:YLL043W(gene)|ensemblfungi:YLL043W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006846"(acetate transport)|go:"GO:0015168"(glycerol transmembrane transporter activity)|go:"GO:0015254"(glycerol channel activity)|go:"GO:0015700"(arsenite transport)|go:"GO:0015791"(polyol transport)|go:"GO:0015793"(glycerol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|reactome:R-SCE-432030|reactome:R-SCE-432040|reactome:R-SCE-432047 psi-mi:"MI:0469"(intact) crc64:8B7F009521F72C15 - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:cpETK9YeU5MA32QUqe9ZeCqJfqE559292 intact-crc:9214A917A0B9F04F|rigid:o6LvFQI6mg0urRKYHyKRTDic7LE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23900 uniprotkb:P23900 intact:EBI-7074|uniprotkb:D6VXW3|ensemblfungi:YLL043W intact:EBI-7074|uniprotkb:D6VXW3|ensemblfungi:YLL043W psi-mi:fps1_yeast(display_long)|uniprotkb:YLL043W(locus name)|uniprotkb:FPS1(gene name)|psi-mi:FPS1(display_short) psi-mi:fps1_yeast(display_long)|uniprotkb:YLL043W(locus name)|uniprotkb:FPS1(gene name)|psi-mi:FPS1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318904|imex:IM-14275-455 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013057.1|sgd:S000003966|dip:DIP-3979N|mint:P23900|ensemblfungi:YLL043W(gene)|ensemblfungi:YLL043W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006846"(acetate transport)|go:"GO:0015168"(glycerol transmembrane transporter activity)|go:"GO:0015254"(glycerol channel activity)|go:"GO:0015700"(arsenite transport)|go:"GO:0015791"(polyol transport)|go:"GO:0015793"(glycerol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|reactome:R-SCE-432030|reactome:R-SCE-432040|reactome:R-SCE-432047 refseq:NP_013057.1|sgd:S000003966|dip:DIP-3979N|mint:P23900|ensemblfungi:YLL043W(gene)|ensemblfungi:YLL043W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006846"(acetate transport)|go:"GO:0015168"(glycerol transmembrane transporter activity)|go:"GO:0015254"(glycerol channel activity)|go:"GO:0015700"(arsenite transport)|go:"GO:0015791"(polyol transport)|go:"GO:0015793"(glycerol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|reactome:R-SCE-432030|reactome:R-SCE-432040|reactome:R-SCE-432047 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cpETK9YeU5MA32QUqe9ZeCqJfqE559292 rogid:cpETK9YeU5MA32QUqe9ZeCqJfqE559292 intact-crc:920713FB7ACE3B15|rigid:8SMWudEE0SQ/HM6PIXAhnkofVyQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23900 uniprotkb:P36027 intact:EBI-7074|uniprotkb:D6VXW3|ensemblfungi:YLL043W intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:fps1_yeast(display_long)|uniprotkb:YLL043W(locus name)|uniprotkb:FPS1(gene name)|psi-mi:FPS1(display_short) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318926|imex:IM-14275-457 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013057.1|sgd:S000003966|dip:DIP-3979N|mint:P23900|ensemblfungi:YLL043W(gene)|ensemblfungi:YLL043W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006846"(acetate transport)|go:"GO:0015168"(glycerol transmembrane transporter activity)|go:"GO:0015254"(glycerol channel activity)|go:"GO:0015700"(arsenite transport)|go:"GO:0015791"(polyol transport)|go:"GO:0015793"(glycerol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|reactome:R-SCE-432030|reactome:R-SCE-432040|reactome:R-SCE-432047 ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cpETK9YeU5MA32QUqe9ZeCqJfqE559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:2BE38BCE9FC1F7C5|rigid:gMrOhgT9F/6PYAMb5Fqts5zL8zY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24276 uniprotkb:P06634 intact:EBI-18153|uniprotkb:D6VSS2|ensemblfungi:YDR293C intact:EBI-5744|uniprotkb:D6W2R0|ensemblfungi:YOR204W psi-mi:ssd1_yeast(display_long)|uniprotkb:SSD1(gene name)|psi-mi:SSD1(display_short)|uniprotkb:CLA1(gene name synonym)|uniprotkb:RLD1(gene name synonym)|uniprotkb:SRK1(gene name synonym)|uniprotkb:YDR293C(locus name)|uniprotkb:D9819.4(orf name)|uniprotkb:Protein SRK1(gene name synonym) psi-mi:ded1_yeast(display_long)|uniprotkb:DED1(gene name)|psi-mi:DED1(display_short)|uniprotkb:SPP81(gene name synonym)|uniprotkb:YOR204W(locus name)|uniprotkb:DEAD box protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318937|imex:IM-14275-458 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010579.1|sgd:S000002701|ensemblfungi:YDR293C(gene)|ensemblfungi:YDR293C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051301"(cell division)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR041093|interpro:IPR041505|rcsb pdb:5NCL|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007049"(cell cycle)|dip:DIP-6449N|mint:P24276 sgd:S000005730|refseq:NP_014847.3|dip:DIP-5820N|mint:P06634|ensemblfungi:YOR204W(gene)|ensemblfungi:YOR204W_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) crc64:3D50FD6838ECA514 crc64:B6722D94C03BFA4B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:myt8+lnu2/li6TuGiM5GBfMtUiw559292 rogid:FkldumX6m5gBuuaG09aTJ0kuMZM559292 intact-crc:4EA1D7921B1290FC|rigid:tukDDZsdDONetw0StDme2EOXzRE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24276 uniprotkb:P11986 intact:EBI-18153|uniprotkb:D6VSS2|ensemblfungi:YDR293C intact:EBI-9257|ensemblfungi:YJL153C|uniprotkb:D6VW34 psi-mi:ssd1_yeast(display_long)|uniprotkb:SSD1(gene name)|psi-mi:SSD1(display_short)|uniprotkb:CLA1(gene name synonym)|uniprotkb:RLD1(gene name synonym)|uniprotkb:SRK1(gene name synonym)|uniprotkb:YDR293C(locus name)|uniprotkb:D9819.4(orf name)|uniprotkb:Protein SRK1(gene name synonym) psi-mi:ino1_yeast(display_long)|uniprotkb:INO1(gene name)|psi-mi:INO1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym)|uniprotkb:J0610(orf name)|uniprotkb:YJL153C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318948|imex:IM-14275-459 author score:94.85 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010579.1|sgd:S000002701|ensemblfungi:YDR293C(gene)|ensemblfungi:YDR293C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051301"(cell division)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR041093|interpro:IPR041505|rcsb pdb:5NCL|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007049"(cell cycle)|dip:DIP-6449N|mint:P24276 rcsb pdb:1P1K|ensemblfungi:YJL153C(gene)|ensemblfungi:YJL153C_mRNA(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|rcsb pdb:1JKF|rcsb pdb:1JKI|rcsb pdb:1LA2|rcsb pdb:1P1F|rcsb pdb:1P1H|rcsb pdb:1P1I|rcsb pdb:1P1J|rcsb pdb:1RM0|reactome:R-SCE-1855183|refseq:NP_012382.2|sgd:S000003689|dip:DIP-5687N|mint:P11986 psi-mi:"MI:0469"(intact) crc64:3D50FD6838ECA514 crc64:282E2AE5D156289D figure legend:tables S3 and S4|author-confidence:94.85|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:myt8+lnu2/li6TuGiM5GBfMtUiw559292 rogid:3OB3q28fOVxXSBMwMpLe2c1g8p8559292 intact-crc:47BFF7D322072084|rigid:wB6WfbG4Rq1nwCIJ1fF2JpnxM+E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24276 uniprotkb:P24276 intact:EBI-18153|uniprotkb:D6VSS2|ensemblfungi:YDR293C intact:EBI-18153|uniprotkb:D6VSS2|ensemblfungi:YDR293C psi-mi:ssd1_yeast(display_long)|uniprotkb:SSD1(gene name)|psi-mi:SSD1(display_short)|uniprotkb:CLA1(gene name synonym)|uniprotkb:RLD1(gene name synonym)|uniprotkb:SRK1(gene name synonym)|uniprotkb:YDR293C(locus name)|uniprotkb:D9819.4(orf name)|uniprotkb:Protein SRK1(gene name synonym) psi-mi:ssd1_yeast(display_long)|uniprotkb:SSD1(gene name)|psi-mi:SSD1(display_short)|uniprotkb:CLA1(gene name synonym)|uniprotkb:RLD1(gene name synonym)|uniprotkb:SRK1(gene name synonym)|uniprotkb:YDR293C(locus name)|uniprotkb:D9819.4(orf name)|uniprotkb:Protein SRK1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318959|imex:IM-14275-460 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010579.1|sgd:S000002701|ensemblfungi:YDR293C(gene)|ensemblfungi:YDR293C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051301"(cell division)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR041093|interpro:IPR041505|rcsb pdb:5NCL|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007049"(cell cycle)|dip:DIP-6449N|mint:P24276 refseq:NP_010579.1|sgd:S000002701|ensemblfungi:YDR293C(gene)|ensemblfungi:YDR293C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051301"(cell division)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR041093|interpro:IPR041505|rcsb pdb:5NCL|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007049"(cell cycle)|dip:DIP-6449N|mint:P24276 psi-mi:"MI:0469"(intact) crc64:3D50FD6838ECA514 crc64:3D50FD6838ECA514 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:myt8+lnu2/li6TuGiM5GBfMtUiw559292 rogid:myt8+lnu2/li6TuGiM5GBfMtUiw559292 intact-crc:4FDF8ABFAF6B8E02|rigid:3V/4A651ov1AH6pUIb4rSVn1EwY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24276 uniprotkb:P25567 intact:EBI-18153|uniprotkb:D6VSS2|ensemblfungi:YDR293C intact:EBI-18084|uniprotkb:D6VQX8|ensemblfungi:YCL037C psi-mi:ssd1_yeast(display_long)|uniprotkb:SSD1(gene name)|psi-mi:SSD1(display_short)|uniprotkb:CLA1(gene name synonym)|uniprotkb:RLD1(gene name synonym)|uniprotkb:SRK1(gene name synonym)|uniprotkb:YDR293C(locus name)|uniprotkb:D9819.4(orf name)|uniprotkb:Protein SRK1(gene name synonym) psi-mi:sro9_yeast(display_long)|uniprotkb:SRO9(gene name)|psi-mi:SRO9(display_short)|uniprotkb:YCL037C(locus name)|uniprotkb:YCL37C(orf name)|uniprotkb:Suppressor of RHO3 protein 9(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318970|imex:IM-14275-461 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010579.1|sgd:S000002701|ensemblfungi:YDR293C(gene)|ensemblfungi:YDR293C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051301"(cell division)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR041093|interpro:IPR041505|rcsb pdb:5NCL|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007049"(cell cycle)|dip:DIP-6449N|mint:P24276 refseq:NP_009893.2|sgd:S000000542|ensemblfungi:YCL037C(gene)|ensemblfungi:YCL037C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|dip:DIP-6638N|mint:P25567 psi-mi:"MI:0469"(intact) crc64:3D50FD6838ECA514 crc64:B1B720D40C7B9914 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:myt8+lnu2/li6TuGiM5GBfMtUiw559292 rogid:CouwiBsK7S3Tm6CoBsu3LdWfelg559292 intact-crc:F230F7E22443FBE0|rigid:r8DvDNXKPT3896zU4+rv8us1ENk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24276 uniprotkb:P32588 intact:EBI-18153|uniprotkb:D6VSS2|ensemblfungi:YDR293C intact:EBI-14231|ensemblfungi:YNL016W|uniprotkb:D6W1G2 psi-mi:ssd1_yeast(display_long)|uniprotkb:SSD1(gene name)|psi-mi:SSD1(display_short)|uniprotkb:CLA1(gene name synonym)|uniprotkb:RLD1(gene name synonym)|uniprotkb:SRK1(gene name synonym)|uniprotkb:YDR293C(locus name)|uniprotkb:D9819.4(orf name)|uniprotkb:Protein SRK1(gene name synonym) psi-mi:pub1_yeast(display_long)|uniprotkb:ARS consensus-binding protein ACBP-60(gene name synonym)|uniprotkb:Poly uridylate-binding protein(gene name synonym)|uniprotkb:PUB1(gene name)|psi-mi:PUB1(display_short)|uniprotkb:RNP1(gene name synonym)|uniprotkb:YNL016W(locus name)|uniprotkb:N2842(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318981|imex:IM-14275-462 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010579.1|sgd:S000002701|ensemblfungi:YDR293C(gene)|ensemblfungi:YDR293C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051301"(cell division)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR041093|interpro:IPR041505|rcsb pdb:5NCL|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007049"(cell cycle)|dip:DIP-6449N|mint:P24276 refseq:NP_014382.1|sgd:S000004961|ensemblfungi:YNL016W(gene)|ensemblfungi:YNL016W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043488"(regulation of mRNA stability)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034509|interpro:IPR034639|interpro:IPR035979|rcsb pdb:2LA4|rcsb pdb:3MD1|rcsb pdb:3MD3|rcsb pdb:6Z29|mint:P32588|dip:DIP-5480N psi-mi:"MI:0469"(intact) crc64:3D50FD6838ECA514 crc64:3B81A7735505D3CA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:myt8+lnu2/li6TuGiM5GBfMtUiw559292 rogid:8xFMuEva7leVYDKg3WOmvPtRTFk559292 intact-crc:5338C88D6757F001|rigid:bazwBIjG8ZgRXkE22Ukk8k5V94A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41811 uniprotkb:P24276 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W intact:EBI-18153|uniprotkb:D6VSS2|ensemblfungi:YDR293C psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:ssd1_yeast(display_long)|uniprotkb:SSD1(gene name)|psi-mi:SSD1(display_short)|uniprotkb:CLA1(gene name synonym)|uniprotkb:RLD1(gene name synonym)|uniprotkb:SRK1(gene name synonym)|uniprotkb:YDR293C(locus name)|uniprotkb:D9819.4(orf name)|uniprotkb:Protein SRK1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6318992|imex:IM-14275-463 author score:97.40 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_010579.1|sgd:S000002701|ensemblfungi:YDR293C(gene)|ensemblfungi:YDR293C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051301"(cell division)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR041093|interpro:IPR041505|rcsb pdb:5NCL|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007049"(cell cycle)|dip:DIP-6449N|mint:P24276 psi-mi:"MI:0469"(intact) crc64:6A5E50BBEB02CB58 crc64:3D50FD6838ECA514 figure legend:tables S3 and S4|author-confidence:97.40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 rogid:myt8+lnu2/li6TuGiM5GBfMtUiw559292 intact-crc:973AFECB5996CC45|rigid:0HIYPrlXm1Xkwvr5EtJrAu2Xj2A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24276 uniprotkb:P53235 intact:EBI-18153|uniprotkb:D6VSS2|ensemblfungi:YDR293C intact:EBI-23172|uniprotkb:D6VUI9|uniprotkb:Q45U32|ensemblfungi:YGR054W psi-mi:ssd1_yeast(display_long)|uniprotkb:SSD1(gene name)|psi-mi:SSD1(display_short)|uniprotkb:CLA1(gene name synonym)|uniprotkb:RLD1(gene name synonym)|uniprotkb:SRK1(gene name synonym)|uniprotkb:YDR293C(locus name)|uniprotkb:D9819.4(orf name)|uniprotkb:Protein SRK1(gene name synonym) psi-mi:eif2a_yeast(display_long)|uniprotkb:YGR054W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319003|imex:IM-14275-464 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010579.1|sgd:S000002701|ensemblfungi:YDR293C(gene)|ensemblfungi:YDR293C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051301"(cell division)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR041093|interpro:IPR041505|rcsb pdb:5NCL|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007049"(cell cycle)|dip:DIP-6449N|mint:P24276 sgd:S000003286|refseq:NP_011568.3|dip:DIP-5518N|mint:P53235|ensemblfungi:YGR054W(gene)|ensemblfungi:YGR054W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like) psi-mi:"MI:0469"(intact) crc64:3D50FD6838ECA514 crc64:F3C2E78504D83418 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:myt8+lnu2/li6TuGiM5GBfMtUiw559292 rogid:x8zDCH5W5GusC7qYd0mDATXhGVI559292 intact-crc:01D8F9D1E8FE7E8D|rigid:ix7pLPTpBBUG8rMgk3pbmwk5RUI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21304 uniprotkb:P24783 intact:EBI-14328|uniprotkb:D6VYJ9|ensemblfungi:YLR196W intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W psi-mi:pwp1_yeast(display_long)|uniprotkb:L8167.10(orf name)|uniprotkb:YLR196W(locus name)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short) psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319014|imex:IM-14275-465 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013297.1|sgd:S000004186|ensemblfungi:YLR196W(gene)|ensemblfungi:YLR196W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR044285|mint:P21304|dip:DIP-4203N sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) crc64:FC0189B289494AB5 crc64:30FE3D4C7E653120 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Q1nPXtlkpIw8JosaiYX0PSVNaSw559292 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 intact-crc:7BF9A2E0828EB7BB|rigid:FYXdfIMOkgiVee3s4tbhafG28TY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24783 uniprotkb:P24783 intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319025|imex:IM-14275-466 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) crc64:30FE3D4C7E653120 crc64:30FE3D4C7E653120 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 intact-crc:77888E228B766597|rigid:7SSO4CBQW1wJkJisUsYRlVwsOw8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24783 uniprotkb:P27476 intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W intact:EBI-12274|ensemblfungi:YGR159C|uniprotkb:D6VUT9 psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:nsr1_yeast(display_long)|uniprotkb:NSR1(gene name)|psi-mi:NSR1(display_short)|uniprotkb:YGR159C(locus name)|uniprotkb:G7001(orf name)|uniprotkb:p67(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319036|imex:IM-14275-467 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 ensemblfungi:YGR159C(gene)|ensemblfungi:YGR159C_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034276|interpro:IPR035979|interpro:IPR034272|refseq:NP_011675.1|sgd:S000003391|mint:P27476|dip:DIP-5537N psi-mi:"MI:0469"(intact) crc64:30FE3D4C7E653120 crc64:90DEEE7BBC20BC0C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 rogid:q0/AgJC55iTpn/5kCsxal2kQ7Ls559292 intact-crc:DB845DDF2CF2298B|rigid:wiIJtI+FHXSpWXiWp5zMjqxEqjk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24783 uniprotkb:P28007 intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319047|imex:IM-14275-468 author score:91.48 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI psi-mi:"MI:0469"(intact) crc64:30FE3D4C7E653120 crc64:C197FE85644DD0F8 figure legend:tables S3 and S4|author-confidence:91.48|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 intact-crc:BC2DBD8F3D8FEE43|rigid:FIG8bMWAdHKq2HGhoSAeYC1nNkg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24783 uniprotkb:P32495 intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W intact:EBI-12014|ensemblfungi:YDL208W|uniprotkb:D6VRE6 psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:nhp2_yeast(display_long)|uniprotkb:NHP2(gene name)|psi-mi:NHP2(display_short)|uniprotkb:YDL208W(locus name)|uniprotkb:D1045(orf name)|uniprotkb:H/ACA snoRNP protein NHP2(gene name synonym)|uniprotkb:High mobility group-like nuclear protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319058|imex:IM-14275-469 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 ensemblfungi:YDL208W(gene)|ensemblfungi:YDL208W_mRNA(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000493"(box H/ACA snoRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|rcsb pdb:2LBW|rcsb pdb:2LBX|refseq:NP_010073.2|sgd:S000002367|mint:P32495|dip:DIP-5134N psi-mi:"MI:0469"(intact) crc64:30FE3D4C7E653120 crc64:008188132B494E5D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 rogid:p5AQTuMF3Vvdu6HWSTYjdjjE1Vs559292 intact-crc:B6DEB5A6A583E5D5|rigid:T7R+uYEdFDZ2QTf009hqijCq10c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32583 uniprotkb:P24783 intact:EBI-17992|uniprotkb:D6VXF2|ensemblfungi:YKR092C intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W psi-mi:srp40_yeast(display_long)|uniprotkb:YKR412A(orf name)|uniprotkb:YKR092C(locus name)|uniprotkb:SRP40(gene name)|psi-mi:SRP40(display_short) psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319069|imex:IM-14275-470 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001800|ensemblfungi:YKR092C(gene)|ensemblfungi:YKR092C_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006913"(nucleocytoplasmic transport)|interpro:IPR007718(SRP40, C-terminal)|refseq:NP_013018.3|dip:DIP-2115N|mint:P32583 sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) crc64:8EA007695AF4BA1D crc64:30FE3D4C7E653120 figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:bk2gXF1o2Rj+ML2zHj1N52chwMc559292 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 intact-crc:99450DD05509F185|rigid:fFGsf6x9GJQXlLimY3CPhzF+5hQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38779 uniprotkb:P24783 intact:EBI-24538|uniprotkb:D3DL01|ensemblfungi:YHR052W intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W psi-mi:cic1_yeast(display_long)|uniprotkb:CIC1(gene name)|psi-mi:CIC1(display_short)|uniprotkb:NSA3(gene name synonym)|uniprotkb:Core interacting component 1(gene name synonym)|uniprotkb:YHR052W(locus name) psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319080|imex:IM-14275-471 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011919.1|sgd:S000001094|dip:DIP-6491N|mint:P38779|ensemblfungi:YHR052W(gene)|ensemblfungi:YHR052W_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0019843"(rRNA binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0070628"(proteasome binding)|interpro:IPR023674|interpro:IPR028364|interpro:IPR028365|rcsb pdb:3JCT|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6M62|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BTB|go:"GO:0034513"(box H/ACA snoRNA binding) sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) crc64:13A2AFA0B927CD98 crc64:30FE3D4C7E653120 figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rdhoaLdCr+bDCy9BYwEA9foQFWQ559292 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 intact-crc:6BBF91955706E66E|rigid:uQlQJD+pWJeISRnV7Czxv5n6Z8A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39744 uniprotkb:P24783 intact:EBI-29259|uniprotkb:Q08625|uniprotkb:D6W2R2|ensemblfungi:YOR206W intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W psi-mi:noc2_yeast(display_long)|uniprotkb:YOX001(orf name)|uniprotkb:YOR206W(locus name)|uniprotkb:NOC2(gene name)|psi-mi:NOC2(display_short) psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319102|imex:IM-14275-473 author score:99.26 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014849.3|sgd:S000005732|dip:DIP-4559N|mint:P39744|ensemblfungi:YOR206W(gene)|ensemblfungi:YOR206W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR005343(Protein of unknown function UPF0120) sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) crc64:48C3B9AE076B9B8F crc64:30FE3D4C7E653120 figure legend:tables S3 and S4|author-confidence:99.26|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:d5I8KJOSG63bZ/Pt+XvKdy/SWws559292 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 intact-crc:BB76114811C40909|rigid:HPgwN5PE3T4PHMdEakjTgeGUk5c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24783 uniprotkb:P38801 intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W intact:EBI-1909|uniprotkb:D3DL32|ensemblfungi:YHR081W psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:lrp1_yeast(display_long)|uniprotkb:LRP1(gene name)|psi-mi:LRP1(display_short)|uniprotkb:Like an rRNA processing protein 1(gene name synonym)|uniprotkb:rRNA processing protein 47(gene name synonym)|uniprotkb:RRP47(gene name synonym)|uniprotkb:YC1D(gene name synonym)|uniprotkb:Yeast C1D domain-containing protein(gene name synonym)|uniprotkb:YHR081W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319091|imex:IM-14275-472 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 refseq:NP_011949.1|sgd:S000001123|dip:DIP-4359N|mint:P38801|ensemblfungi:YHR081W(gene)|ensemblfungi:YHR081W_mRNA(transcript)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071033"|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1901917"(regulation of exoribonuclease activity)|interpro:IPR007146(Small-subunit processome, Utp3)|interpro:IPR011082(Exosome-associated factor Rrp47/DNA strand repair C1D)|rcsb pdb:4WFC|rcsb pdb:4WFD|rcsb pdb:5C0W|rcsb pdb:6FSZ|rcsb pdb:6FT6|rcsb pdb:6LQS|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:30FE3D4C7E653120 crc64:27D00668C296CC9A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 rogid:cQaT2zPsTCZHkLjuYBNF012Ym38559292 intact-crc:36D34302EABE0F3D|rigid:3AMJDNKTymoHZaobV2BWndKUf2w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53131 uniprotkb:P24783 intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319124|imex:IM-14275-475 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131 sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) crc64:DA8A085EC50FF430 crc64:30FE3D4C7E653120 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 intact-crc:19B2D0941015781C|rigid:6N2mviClpZ6SqoPsqYDcADAgWcM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24783 uniprotkb:P40040 intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W intact:EBI-19254|uniprotkb:D3DLW8|ensemblfungi:YER063W psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:tho1_yeast(display_long)|uniprotkb:YER063W(locus name)|uniprotkb:THO1(gene name)|psi-mi:THO1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319113|imex:IM-14275-474 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 refseq:NP_010985.1|sgd:S000000865|ensemblfungi:YER063W(gene)|ensemblfungi:YER063W_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0022618"(ribonucleoprotein complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR036361|interpro:IPR040746|rcsb pdb:1H1J|rcsb pdb:2WQG|rcsb pdb:4UZW|rcsb pdb:4UZX|dip:DIP-3983N|mint:P40040 psi-mi:"MI:0469"(intact) crc64:30FE3D4C7E653120 - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 rogid:eP5eukamLvSYux9zzcnLzLq7nPY559292 intact-crc:3EEAE55B589AAF6F|rigid:fxh0F6jKHTfJqoAnhfqP1O57eCs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53849 uniprotkb:P24783 intact:EBI-29244|uniprotkb:D6W0T8|ensemblfungi:YNL255C intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W psi-mi:gis2_yeast(display_long)|uniprotkb:GIS2(gene name)|psi-mi:GIS2(display_short)|uniprotkb:N0852(orf name)|uniprotkb:YNL255C(locus name) psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319135|imex:IM-14275-476 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014144.1|sgd:S000005199|dip:DIP-2669N|mint:P53849|ensemblfungi:YNL255C(gene)|ensemblfungi:YNL255C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045182"(translation regulator activity)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875 sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) crc64:E72696428F85CA3F crc64:30FE3D4C7E653120 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kftHFJVi7QRZASmr4hLdALvleR4559292 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 intact-crc:F73F04E59F594D76|rigid:kbIsBi/Vy6WmmSlyAEJbxFkOUaM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53874 uniprotkb:P24783 intact:EBI-19873|uniprotkb:D6W101|ensemblfungi:YNL186W intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W psi-mi:ubp10_yeast(display_long)|uniprotkb:UBP10(gene name)|psi-mi:UBP10(display_short)|uniprotkb:YNL186W(locus name)|uniprotkb:N1619(orf name)|uniprotkb:Ubiquitin-specific-processing protease 10(gene name synonym)|uniprotkb:Deubiquitinating enzyme 10(gene name synonym)|uniprotkb:Disrupter of telomere silencing protein 4(gene name synonym)|uniprotkb:Ubiquitin thioesterase 10(gene name synonym)|uniprotkb:DOT4(gene name synonym) psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319146|imex:IM-14275-477 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014213.2|sgd:S000005130|ensemblfungi:YNL186W(gene)|ensemblfungi:YNL186W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0043596"(nuclear replication fork)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|rcsb pdb:6RR0|dip:DIP-6664N|mint:P53874 sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) - crc64:30FE3D4C7E653120 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Z1rRAI9RLgHeGd7QwLbrf51v5LY559292 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 intact-crc:B84AB17768B08434|rigid:6Ga+caqDW8WH+lUA/ujl4cmNbU4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24783 uniprotkb:Q08235 intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W intact:EBI-3775|uniprotkb:D6W1Z1|ensemblfungi:YOL077C psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:brx1_yeast(display_long)|uniprotkb:YOL077C(locus name)|uniprotkb:BRX1(gene name)|psi-mi:BRX1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319157|imex:IM-14275-478 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 refseq:NP_014565.2|sgd:S000005437|dip:DIP-6317N|mint:Q08235|ensemblfungi:YOL077C(gene)|ensemblfungi:YOL077C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000464"("endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000465"("exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR007109(Brix)|interpro:IPR026532|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5 psi-mi:"MI:0469"(intact) crc64:30FE3D4C7E653120 crc64:31466853EF0E7301 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 rogid:mPR6HWKwM6RNCRE/vezsYlCmEGY559292 intact-crc:0E5EC871E9E8AAA7|rigid:AU8X8L0Er8207h7luuv4y1TxBtI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6Q547 uniprotkb:P24783 intact:EBI-2052475|uniprotkb:D3DL22|ensemblfungi:YHR072W-A intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W psi-mi:nop10_yeast(display_long)|uniprotkb:YHR072W-A(locus name)|uniprotkb:Nucleolar protein family A member 3(gene name synonym)|uniprotkb:snoRNP protein NOP10(gene name synonym)|uniprotkb:NOP10(gene name)|psi-mi:NOP10(display_short)|uniprotkb:Nucleolar protein 10(gene name synonym) psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319168|imex:IM-14275-479 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058135.1|sgd:S000007455|dip:DIP-5845N|mint:Q6Q547|ensemblfungi:YHR072W-A(gene)|ensemblfungi:YHR072W-A_mRNA(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|interpro:IPR007264(Nucleolar RNA-binding protein Nop10p)|interpro:IPR036756|rcsb pdb:1Y2Y|rcsb pdb:2AQA|rcsb pdb:3U28|rcsb pdb:3UAI sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) crc64:4718D35AF7911FBA crc64:30FE3D4C7E653120 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9m0x3DatObFwua2cbCQYMRKGqrU559292 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 intact-crc:62F46258930686FB|rigid:xJVq30KN1bJhSCH29i4dGrUOAGI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06634 uniprotkb:P24784 intact:EBI-5744|uniprotkb:D6W2R0|ensemblfungi:YOR204W intact:EBI-5596|uniprotkb:P20446|uniprotkb:D6W3P9|ensemblfungi:YPL119C psi-mi:ded1_yeast(display_long)|uniprotkb:DED1(gene name)|psi-mi:DED1(display_short)|uniprotkb:SPP81(gene name synonym)|uniprotkb:YOR204W(locus name)|uniprotkb:DEAD box protein 1(gene name synonym) psi-mi:dbp1_yeast(display_long)|uniprotkb:DBP1(gene name)|psi-mi:DBP1(display_short)|uniprotkb:YPL119C(locus name)|uniprotkb:LPH8C(orf name)|uniprotkb:DEAD box protein 1(gene name synonym)|uniprotkb:Helicase CA1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319179|imex:IM-14275-480 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005730|refseq:NP_014847.3|dip:DIP-5820N|mint:P06634|ensemblfungi:YOR204W(gene)|ensemblfungi:YOR204W_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763|reactome:R-SCE-6798695 refseq:NP_015206.1|sgd:S000006040|dip:DIP-2576N|mint:P24784|ensemblfungi:YPL119C(gene)|ensemblfungi:YPL119C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763 psi-mi:"MI:0469"(intact) crc64:B6722D94C03BFA4B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FkldumX6m5gBuuaG09aTJ0kuMZM559292 rogid:8TFwSQq3dopTasOH0G/KZ12DDGE559292 intact-crc:FFA407EBB492F119|rigid:ViW4daqDyjZldSTusJ5qfTWmLYs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24784 uniprotkb:P24784 intact:EBI-5596|uniprotkb:P20446|uniprotkb:D6W3P9|ensemblfungi:YPL119C intact:EBI-5596|uniprotkb:P20446|uniprotkb:D6W3P9|ensemblfungi:YPL119C psi-mi:dbp1_yeast(display_long)|uniprotkb:DBP1(gene name)|psi-mi:DBP1(display_short)|uniprotkb:YPL119C(locus name)|uniprotkb:LPH8C(orf name)|uniprotkb:DEAD box protein 1(gene name synonym)|uniprotkb:Helicase CA1(gene name synonym) psi-mi:dbp1_yeast(display_long)|uniprotkb:DBP1(gene name)|psi-mi:DBP1(display_short)|uniprotkb:YPL119C(locus name)|uniprotkb:LPH8C(orf name)|uniprotkb:DEAD box protein 1(gene name synonym)|uniprotkb:Helicase CA1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319201|imex:IM-14275-482 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015206.1|sgd:S000006040|dip:DIP-2576N|mint:P24784|ensemblfungi:YPL119C(gene)|ensemblfungi:YPL119C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763 refseq:NP_015206.1|sgd:S000006040|dip:DIP-2576N|mint:P24784|ensemblfungi:YPL119C(gene)|ensemblfungi:YPL119C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8TFwSQq3dopTasOH0G/KZ12DDGE559292 rogid:8TFwSQq3dopTasOH0G/KZ12DDGE559292 intact-crc:CEA7BFCF40D737F7|rigid:Non/5x2067LAxviC5ycJapfw+9s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24784 uniprotkb:P24276 intact:EBI-5596|uniprotkb:P20446|uniprotkb:D6W3P9|ensemblfungi:YPL119C intact:EBI-18153|uniprotkb:D6VSS2|ensemblfungi:YDR293C psi-mi:dbp1_yeast(display_long)|uniprotkb:DBP1(gene name)|psi-mi:DBP1(display_short)|uniprotkb:YPL119C(locus name)|uniprotkb:LPH8C(orf name)|uniprotkb:DEAD box protein 1(gene name synonym)|uniprotkb:Helicase CA1(gene name synonym) psi-mi:ssd1_yeast(display_long)|uniprotkb:SSD1(gene name)|psi-mi:SSD1(display_short)|uniprotkb:CLA1(gene name synonym)|uniprotkb:RLD1(gene name synonym)|uniprotkb:SRK1(gene name synonym)|uniprotkb:YDR293C(locus name)|uniprotkb:D9819.4(orf name)|uniprotkb:Protein SRK1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319190|imex:IM-14275-481 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015206.1|sgd:S000006040|dip:DIP-2576N|mint:P24784|ensemblfungi:YPL119C(gene)|ensemblfungi:YPL119C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763 refseq:NP_010579.1|sgd:S000002701|ensemblfungi:YDR293C(gene)|ensemblfungi:YDR293C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051301"(cell division)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR041093|interpro:IPR041505|rcsb pdb:5NCL|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007049"(cell cycle)|dip:DIP-6449N|mint:P24276 psi-mi:"MI:0469"(intact) - crc64:3D50FD6838ECA514 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8TFwSQq3dopTasOH0G/KZ12DDGE559292 rogid:myt8+lnu2/li6TuGiM5GBfMtUiw559292 intact-crc:7F16239E1E86DB69|rigid:qz44GLrDyo6uiAPMs3dE9kGnvjY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32588 uniprotkb:P24784 intact:EBI-14231|ensemblfungi:YNL016W|uniprotkb:D6W1G2 intact:EBI-5596|uniprotkb:P20446|uniprotkb:D6W3P9|ensemblfungi:YPL119C psi-mi:pub1_yeast(display_long)|uniprotkb:ARS consensus-binding protein ACBP-60(gene name synonym)|uniprotkb:Poly uridylate-binding protein(gene name synonym)|uniprotkb:PUB1(gene name)|psi-mi:PUB1(display_short)|uniprotkb:RNP1(gene name synonym)|uniprotkb:YNL016W(locus name)|uniprotkb:N2842(orf name) psi-mi:dbp1_yeast(display_long)|uniprotkb:DBP1(gene name)|psi-mi:DBP1(display_short)|uniprotkb:YPL119C(locus name)|uniprotkb:LPH8C(orf name)|uniprotkb:DEAD box protein 1(gene name synonym)|uniprotkb:Helicase CA1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319212|imex:IM-14275-483 author score:97.40 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014382.1|sgd:S000004961|ensemblfungi:YNL016W(gene)|ensemblfungi:YNL016W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043488"(regulation of mRNA stability)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034509|interpro:IPR034639|interpro:IPR035979|rcsb pdb:2LA4|rcsb pdb:3MD1|rcsb pdb:3MD3|rcsb pdb:6Z29|mint:P32588|dip:DIP-5480N refseq:NP_015206.1|sgd:S000006040|dip:DIP-2576N|mint:P24784|ensemblfungi:YPL119C(gene)|ensemblfungi:YPL119C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763 psi-mi:"MI:0469"(intact) crc64:3B81A7735505D3CA - figure legend:tables S3 and S4|author-confidence:97.40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8xFMuEva7leVYDKg3WOmvPtRTFk559292 rogid:8TFwSQq3dopTasOH0G/KZ12DDGE559292 intact-crc:63452B442F4B2811|rigid:Xp6TYPhqnogcEw2TSBxzb4fvpR8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24784 uniprotkb:P50109 intact:EBI-5596|uniprotkb:P20446|uniprotkb:D6W3P9|ensemblfungi:YPL119C intact:EBI-14050|uniprotkb:Q07170|uniprotkb:Q870H3|ensemblfungi:YML017W|uniprotkb:D6VZF7 psi-mi:dbp1_yeast(display_long)|uniprotkb:DBP1(gene name)|psi-mi:DBP1(display_short)|uniprotkb:YPL119C(locus name)|uniprotkb:LPH8C(orf name)|uniprotkb:DEAD box protein 1(gene name synonym)|uniprotkb:Helicase CA1(gene name synonym) psi-mi:psp2_yeast(display_long)|uniprotkb:PSP2(gene name)|psi-mi:PSP2(display_short)|uniprotkb:YML017W(locus name)|uniprotkb:YM9571.01(orf name)|uniprotkb:Polymerase suppressor protein 2(gene name synonym)|uniprotkb:Mitochondrial regulator of splicing 15(gene name synonym)|uniprotkb:MRS15(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319223|imex:IM-14275-484 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015206.1|sgd:S000006040|dip:DIP-2576N|mint:P24784|ensemblfungi:YPL119C(gene)|ensemblfungi:YPL119C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763 sgd:S000004479|refseq:NP_013695.2|ensemblfungi:YML017W(gene)|ensemblfungi:YML017W_mRNA(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0000932"(P-body)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|reactome:R-SCE-6791226|go:"GO:0003723"(RNA binding)|mint:P50109 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8TFwSQq3dopTasOH0G/KZ12DDGE559292 rogid:IW+vaICiPBsINLxQCo1dNXRX5Lw559292 intact-crc:705BB147ACA835F9|rigid:mRlE9j+0GPeH09zrFs1aKG/WyRU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53849 uniprotkb:P24784 intact:EBI-29244|uniprotkb:D6W0T8|ensemblfungi:YNL255C intact:EBI-5596|uniprotkb:P20446|uniprotkb:D6W3P9|ensemblfungi:YPL119C psi-mi:gis2_yeast(display_long)|uniprotkb:GIS2(gene name)|psi-mi:GIS2(display_short)|uniprotkb:N0852(orf name)|uniprotkb:YNL255C(locus name) psi-mi:dbp1_yeast(display_long)|uniprotkb:DBP1(gene name)|psi-mi:DBP1(display_short)|uniprotkb:YPL119C(locus name)|uniprotkb:LPH8C(orf name)|uniprotkb:DEAD box protein 1(gene name synonym)|uniprotkb:Helicase CA1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319234|imex:IM-14275-485 author score:97.40 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014144.1|sgd:S000005199|dip:DIP-2669N|mint:P53849|ensemblfungi:YNL255C(gene)|ensemblfungi:YNL255C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045182"(translation regulator activity)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875 refseq:NP_015206.1|sgd:S000006040|dip:DIP-2576N|mint:P24784|ensemblfungi:YPL119C(gene)|ensemblfungi:YPL119C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763 psi-mi:"MI:0469"(intact) crc64:E72696428F85CA3F - figure legend:tables S3 and S4|author-confidence:97.40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kftHFJVi7QRZASmr4hLdALvleR4559292 rogid:8TFwSQq3dopTasOH0G/KZ12DDGE559292 intact-crc:F03F023AA51584B8|rigid:79otDbGq1rkBtnrvnyEQXPylWWU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02825 uniprotkb:P25042 intact:EBI-16829|uniprotkb:D6W3T4|ensemblfungi:YPL083C intact:EBI-15714|uniprotkb:D6W469|ensemblfungi:YPR065W psi-mi:sen54_yeast(display_long)|uniprotkb:SEN54(gene name)|psi-mi:SEN54(display_short)|uniprotkb:YPL083C(locus name)|uniprotkb:LPF3C(orf name)|uniprotkb:tRNA-intron endonuclease SEN54(gene name synonym)|uniprotkb:Splicing endonuclease of 54 kDa(gene name synonym) psi-mi:rox1_yeast(display_long)|uniprotkb:ROX1(gene name)|psi-mi:ROX1(display_short)|uniprotkb:YPR065W(locus name)|uniprotkb:YP9499.20(orf name)|uniprotkb:Hypoxic function repressor(gene name synonym)|uniprotkb:Heme-dependent repression factor(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319245|imex:IM-14275-486 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL083C(gene)|ensemblfungi:YPL083C_mRNA(transcript)|go:"GO:0000214"(tRNA-intron endonuclease complex)|go:"GO:0000379"(tRNA-type intron splice site recognition and cleavage)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR024336|interpro:IPR024337|refseq:NP_015242.1|sgd:S000006004|dip:DIP-4452N|mint:Q02825 refseq:NP_015390.1|sgd:S000006269|ensemblfungi:YPR065W(gene)|ensemblfungi:YPR065W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|dip:DIP-4651N|mint:P25042 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:B3HByPP2gu+B5283ZPc8RZ/YAFw559292 rogid:8vTgyeKnMSmuQHb10O5eGtBjn6g559292 intact-crc:9B53D137B087C3E7|rigid:GVemPzeMvNMH/XMcBqyJsIkNglk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25045 uniprotkb:P36027 intact:EBI-10059|uniprotkb:D6W0C3|ensemblfungi:YMR296C intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:lcb1_yeast(display_long)|uniprotkb:YMR296C(locus name)|uniprotkb:LCB1(gene name)|psi-mi:LCB1(display_short)|uniprotkb:END8(gene name synonym)|uniprotkb:TSC2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319267|imex:IM-14275-488 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014025.1|sgd:S000004911|ensemblfungi:YMR296C_mRNA(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|ensemblfungi:YMR296C(gene)|dip:DIP-5249N|mint:P25045 ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) crc64:9F7F93E4B2C70FDB - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:maw7eX1MYPojWGQUtWBPX7Qn8wI559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:46F6E19EC58AA5D4|rigid:jhNXry07yH914AFt3MY1XfRjS9A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25045 uniprotkb:P14359 intact:EBI-10059|uniprotkb:D6W0C3|ensemblfungi:YMR296C intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:lcb1_yeast(display_long)|uniprotkb:YMR296C(locus name)|uniprotkb:LCB1(gene name)|psi-mi:LCB1(display_short)|uniprotkb:END8(gene name synonym)|uniprotkb:TSC2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319256|imex:IM-14275-487 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014025.1|sgd:S000004911|ensemblfungi:YMR296C_mRNA(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|ensemblfungi:YMR296C(gene)|dip:DIP-5249N|mint:P25045 refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) crc64:9F7F93E4B2C70FDB crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:maw7eX1MYPojWGQUtWBPX7Qn8wI559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:83C2980669ED6CC4|rigid:NRKipYp3otPK0o3FR05EfsXgg6E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25293 uniprotkb:P20485 intact:EBI-11850|uniprotkb:P87196|ensemblfungi:YKR048C|uniprotkb:D6VXA9 intact:EBI-9699|ensemblfungi:YLR133W|uniprotkb:D6VYC8 psi-mi:nap1_yeast(display_long)|uniprotkb:NAP1(gene name)|psi-mi:NAP1(display_short)|uniprotkb:YKR048C(locus name) psi-mi:kich_yeast(display_long)|uniprotkb:CKI1(gene name)|psi-mi:CKI1(display_short)|uniprotkb:CKI(gene name synonym)|uniprotkb:YLR133W(locus name)|uniprotkb:L3130(orf name)|uniprotkb:L9606.8(orf name)|uniprotkb:"ATP:choline phosphotransferase"(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319278|imex:IM-14275-489 author score:99.34 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YKR048C(gene)|ensemblfungi:YKR048C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032153"(cell division site)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0098841"(protein localization to cell division site after cytokinesis)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|rcsb pdb:2AYU|rcsb pdb:2Z2R|rcsb pdb:5G2E|go:"GO:0032174"(cellular bud neck septin collar)|refseq:NP_012974.1|sgd:S000001756|dip:DIP-1380N|mint:P25293 ensemblfungi:YLR133W(gene)|ensemblfungi:YLR133W_mRNA(transcript)|go:"GO:0004103"(choline kinase activity)|go:"GO:0004305"(ethanolamine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|interpro:IPR007521(Choline kinase, N-terminal)|interpro:IPR011009(Protein kinase-like)|reactome:R-SCE-1483191|reactome:R-SCE-1483213|refseq:NP_013234.1|sgd:S000004123|mint:P20485|dip:DIP-2617N psi-mi:"MI:0469"(intact) crc64:C0F97FBA1B9EEA83 crc64:68C395B9CC120A0E figure legend:tables S3 and S4|author-confidence:99.34|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MBxVJ0JmlEg5coqnQd6uoSX2uC0559292 rogid:JAeKrnUWBWBElM5OPJ0A43K+pGQ559292 intact-crc:4871615CA293B5B4|rigid:6F55W2+K0zn4/5Ve+lH6m34Y7Lg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25293 uniprotkb:P25293 intact:EBI-11850|uniprotkb:P87196|ensemblfungi:YKR048C|uniprotkb:D6VXA9 intact:EBI-11850|uniprotkb:P87196|ensemblfungi:YKR048C|uniprotkb:D6VXA9 psi-mi:nap1_yeast(display_long)|uniprotkb:NAP1(gene name)|psi-mi:NAP1(display_short)|uniprotkb:YKR048C(locus name) psi-mi:nap1_yeast(display_long)|uniprotkb:NAP1(gene name)|psi-mi:NAP1(display_short)|uniprotkb:YKR048C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319289|imex:IM-14275-490 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YKR048C(gene)|ensemblfungi:YKR048C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032153"(cell division site)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0098841"(protein localization to cell division site after cytokinesis)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|rcsb pdb:2AYU|rcsb pdb:2Z2R|rcsb pdb:5G2E|go:"GO:0032174"(cellular bud neck septin collar)|refseq:NP_012974.1|sgd:S000001756|dip:DIP-1380N|mint:P25293 ensemblfungi:YKR048C(gene)|ensemblfungi:YKR048C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032153"(cell division site)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0098841"(protein localization to cell division site after cytokinesis)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|rcsb pdb:2AYU|rcsb pdb:2Z2R|rcsb pdb:5G2E|go:"GO:0032174"(cellular bud neck septin collar)|refseq:NP_012974.1|sgd:S000001756|dip:DIP-1380N|mint:P25293 psi-mi:"MI:0469"(intact) crc64:C0F97FBA1B9EEA83 crc64:C0F97FBA1B9EEA83 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MBxVJ0JmlEg5coqnQd6uoSX2uC0559292 rogid:MBxVJ0JmlEg5coqnQd6uoSX2uC0559292 intact-crc:1CB14D4A374D3073|rigid:Qlq5XGctE6OLAMV11Rx7Vjr+Tm4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25567 uniprotkb:P25293 intact:EBI-18084|uniprotkb:D6VQX8|ensemblfungi:YCL037C intact:EBI-11850|uniprotkb:P87196|ensemblfungi:YKR048C|uniprotkb:D6VXA9 psi-mi:sro9_yeast(display_long)|uniprotkb:SRO9(gene name)|psi-mi:SRO9(display_short)|uniprotkb:YCL037C(locus name)|uniprotkb:YCL37C(orf name)|uniprotkb:Suppressor of RHO3 protein 9(gene name synonym) psi-mi:nap1_yeast(display_long)|uniprotkb:NAP1(gene name)|psi-mi:NAP1(display_short)|uniprotkb:YKR048C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319300|imex:IM-14275-491 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009893.2|sgd:S000000542|ensemblfungi:YCL037C(gene)|ensemblfungi:YCL037C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|dip:DIP-6638N|mint:P25567 ensemblfungi:YKR048C(gene)|ensemblfungi:YKR048C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032153"(cell division site)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0098841"(protein localization to cell division site after cytokinesis)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|rcsb pdb:2AYU|rcsb pdb:2Z2R|rcsb pdb:5G2E|go:"GO:0032174"(cellular bud neck septin collar)|refseq:NP_012974.1|sgd:S000001756|dip:DIP-1380N|mint:P25293 psi-mi:"MI:0469"(intact) crc64:B1B720D40C7B9914 crc64:C0F97FBA1B9EEA83 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CouwiBsK7S3Tm6CoBsu3LdWfelg559292 rogid:MBxVJ0JmlEg5coqnQd6uoSX2uC0559292 intact-crc:7280189552B8DF84|rigid:S3SVrEhe/OvYAHRoaHX5BeznxOM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38344 uniprotkb:P25293 intact:EBI-21136|uniprotkb:D6VQR3|ensemblfungi:YBR267W intact:EBI-11850|uniprotkb:P87196|ensemblfungi:YKR048C|uniprotkb:D6VXA9 psi-mi:rei1_yeast(display_long)|uniprotkb:REI1(gene name)|psi-mi:REI1(display_short)|uniprotkb:Required for isotropic bud growth protein 1(gene name synonym)|uniprotkb:pre-60S factor REI1(gene name synonym)|uniprotkb:YBR1736(orf name)|uniprotkb:YBR267W(locus name) psi-mi:nap1_yeast(display_long)|uniprotkb:NAP1(gene name)|psi-mi:NAP1(display_short)|uniprotkb:YKR048C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319311|imex:IM-14275-492 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009825.4|sgd:S000000471|mint:P38344|dip:DIP-6347N|rcsb pdb:6RZZ|rcsb pdb:5APN|ensemblfungi:YBR267W(gene)|ensemblfungi:YBR267W_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR040025|interpro:IPR041661 ensemblfungi:YKR048C(gene)|ensemblfungi:YKR048C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032153"(cell division site)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0098841"(protein localization to cell division site after cytokinesis)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|rcsb pdb:2AYU|rcsb pdb:2Z2R|rcsb pdb:5G2E|go:"GO:0032174"(cellular bud neck septin collar)|refseq:NP_012974.1|sgd:S000001756|dip:DIP-1380N|mint:P25293 psi-mi:"MI:0469"(intact) crc64:D01AA8FFDF4A0BAC crc64:C0F97FBA1B9EEA83 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YxMyWWxJUH2Pk41X+98x8jcnqhc559292 rogid:MBxVJ0JmlEg5coqnQd6uoSX2uC0559292 intact-crc:DE4497F280FC8D47|rigid:YQV882p/vxjs34Gq1MZaqZr//l0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38615 uniprotkb:P25293 intact:EBI-10642|uniprotkb:Q6Q5K4|ensemblfungi:YMR139W|uniprotkb:D6VZW2 intact:EBI-11850|uniprotkb:P87196|ensemblfungi:YKR048C|uniprotkb:D6VXA9 psi-mi:rim11_yeast(display_long)|uniprotkb:RIM11(gene name)|psi-mi:RIM11(display_short)|uniprotkb:GSK3(gene name synonym)|uniprotkb:MDS1(gene name synonym)|uniprotkb:YMR139W(locus name)|uniprotkb:YM9375.08(orf name)|uniprotkb:Regulator of IME2 protein 11(gene name synonym) psi-mi:nap1_yeast(display_long)|uniprotkb:NAP1(gene name)|psi-mi:NAP1(display_short)|uniprotkb:YKR048C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319322|imex:IM-14275-493 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013859.1|sgd:S000004747|ensemblfungi:YMR139W(gene)|ensemblfungi:YMR139W_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0030437"(ascospore formation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|reactome:R-SCE-3371453|mint:P38615|dip:DIP-1566N ensemblfungi:YKR048C(gene)|ensemblfungi:YKR048C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032153"(cell division site)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0098841"(protein localization to cell division site after cytokinesis)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|rcsb pdb:2AYU|rcsb pdb:2Z2R|rcsb pdb:5G2E|go:"GO:0032174"(cellular bud neck septin collar)|refseq:NP_012974.1|sgd:S000001756|dip:DIP-1380N|mint:P25293 psi-mi:"MI:0469"(intact) crc64:59D92C9D42408E97 crc64:C0F97FBA1B9EEA83 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HR/odTTwzM907syfBEfaJny7t5Q559292 rogid:MBxVJ0JmlEg5coqnQd6uoSX2uC0559292 intact-crc:77C8E0AE3C044411|rigid:CYoGLiPL/Kj8Ry8K1dyLggJ6niQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25293 uniprotkb:Q12163 intact:EBI-11850|uniprotkb:P87196|ensemblfungi:YKR048C|uniprotkb:D6VXA9 intact:EBI-34713|uniprotkb:D6VSE2|ensemblfungi:YDR162C psi-mi:nap1_yeast(display_long)|uniprotkb:NAP1(gene name)|psi-mi:NAP1(display_short)|uniprotkb:YKR048C(locus name) psi-mi:nbp2_yeast(display_long)|uniprotkb:NBP2(gene name)|psi-mi:NBP2(display_short)|uniprotkb:YDR162C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319344|imex:IM-14275-495 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YKR048C(gene)|ensemblfungi:YKR048C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032153"(cell division site)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0098841"(protein localization to cell division site after cytokinesis)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|rcsb pdb:2AYU|rcsb pdb:2Z2R|rcsb pdb:5G2E|go:"GO:0032174"(cellular bud neck septin collar)|refseq:NP_012974.1|sgd:S000001756|dip:DIP-1380N|mint:P25293 sgd:S000002569|refseq:NP_010446.3|mint:Q12163|dip:DIP-1538N|ensemblfungi:YDR162C(gene)|ensemblfungi:YDR162C_mRNA(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|rcsb pdb:1YN8|rcsb pdb:2LCS psi-mi:"MI:0469"(intact) crc64:C0F97FBA1B9EEA83 crc64:A7458854D5000EA6 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MBxVJ0JmlEg5coqnQd6uoSX2uC0559292 rogid:rxEwkyNpxLvCh9usNVTOPCYedkU559292 intact-crc:4EBCD23B7754679E|rigid:2Y+ash/xOYNJgVyZqmyflC3nz1Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53235 uniprotkb:P25293 intact:EBI-23172|uniprotkb:D6VUI9|uniprotkb:Q45U32|ensemblfungi:YGR054W intact:EBI-11850|uniprotkb:P87196|ensemblfungi:YKR048C|uniprotkb:D6VXA9 psi-mi:eif2a_yeast(display_long)|uniprotkb:YGR054W(locus name) psi-mi:nap1_yeast(display_long)|uniprotkb:NAP1(gene name)|psi-mi:NAP1(display_short)|uniprotkb:YKR048C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319333|imex:IM-14275-494 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003286|refseq:NP_011568.3|dip:DIP-5518N|mint:P53235|ensemblfungi:YGR054W(gene)|ensemblfungi:YGR054W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like) ensemblfungi:YKR048C(gene)|ensemblfungi:YKR048C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032153"(cell division site)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0098841"(protein localization to cell division site after cytokinesis)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|rcsb pdb:2AYU|rcsb pdb:2Z2R|rcsb pdb:5G2E|go:"GO:0032174"(cellular bud neck septin collar)|refseq:NP_012974.1|sgd:S000001756|dip:DIP-1380N|mint:P25293 psi-mi:"MI:0469"(intact) crc64:F3C2E78504D83418 crc64:C0F97FBA1B9EEA83 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:x8zDCH5W5GusC7qYd0mDATXhGVI559292 rogid:MBxVJ0JmlEg5coqnQd6uoSX2uC0559292 intact-crc:816816A69E055AE9|rigid:EAIxJ4gHB6zUZ+el16kTlMaytew false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25294 uniprotkb:P22137 intact:EBI-17244|uniprotkb:D6W1H0|ensemblfungi:YNL007C intact:EBI-4766|uniprotkb:D6VTU9|ensemblfungi:YGL206C psi-mi:sis1_yeast(display_long)|uniprotkb:YNL007C(locus name)|uniprotkb:SIS1(gene name)|psi-mi:SIS1(display_short)|uniprotkb:N2879(orf name) psi-mi:clh_yeast(display_long)|uniprotkb:CHC1(gene name)|psi-mi:CHC1(display_short)|uniprotkb:YGL206C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319355|imex:IM-14275-496 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014391.1|sgd:S000004952|ensemblfungi:YNL007C(gene)|ensemblfungi:YNL007C_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006413"(translational initiation)|go:"GO:0006457"(protein folding)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0035719"(tRNA import into nucleus)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070843"(misfolded protein transport)|go:"GO:0071630"(nuclear protein quality control by the ubiquitin-proteasome system)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|rcsb pdb:1C3G|rcsb pdb:2B26|rcsb pdb:4RWU|rcsb pdb:6D6X|go:"GO:0007049"(cell cycle)|dip:DIP-4385N|mint:P25294 refseq:NP_011309.1|sgd:S000003174|dip:DIP-2279N|mint:P22137|ensemblfungi:YGL206C(gene)|ensemblfungi:YGL206C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0071439"(clathrin complex)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-432720|reactome:R-SCE-437239|reactome:R-SCE-8856828|reactome:R-SCE-8866427|reactome:R-SCE-8964038 psi-mi:"MI:0469"(intact) crc64:642D3709C0FD5682 crc64:622F3083DF2FE315 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:gp39i5OLzpajm1XnD9cYtGKD6kU559292 rogid:SAN6H3nVFozXZyTiRLaljMcIKIA559292 intact-crc:505CA9B509971911|rigid:kvyndOptrWT0s/OPEUMaFn6w5Kg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25294 uniprotkb:P25294 intact:EBI-17244|uniprotkb:D6W1H0|ensemblfungi:YNL007C intact:EBI-17244|uniprotkb:D6W1H0|ensemblfungi:YNL007C psi-mi:sis1_yeast(display_long)|uniprotkb:YNL007C(locus name)|uniprotkb:SIS1(gene name)|psi-mi:SIS1(display_short)|uniprotkb:N2879(orf name) psi-mi:sis1_yeast(display_long)|uniprotkb:YNL007C(locus name)|uniprotkb:SIS1(gene name)|psi-mi:SIS1(display_short)|uniprotkb:N2879(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319366|imex:IM-14275-497 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014391.1|sgd:S000004952|ensemblfungi:YNL007C(gene)|ensemblfungi:YNL007C_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006413"(translational initiation)|go:"GO:0006457"(protein folding)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0035719"(tRNA import into nucleus)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070843"(misfolded protein transport)|go:"GO:0071630"(nuclear protein quality control by the ubiquitin-proteasome system)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|rcsb pdb:1C3G|rcsb pdb:2B26|rcsb pdb:4RWU|rcsb pdb:6D6X|go:"GO:0007049"(cell cycle)|dip:DIP-4385N|mint:P25294 refseq:NP_014391.1|sgd:S000004952|ensemblfungi:YNL007C(gene)|ensemblfungi:YNL007C_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006413"(translational initiation)|go:"GO:0006457"(protein folding)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0035719"(tRNA import into nucleus)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070843"(misfolded protein transport)|go:"GO:0071630"(nuclear protein quality control by the ubiquitin-proteasome system)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|rcsb pdb:1C3G|rcsb pdb:2B26|rcsb pdb:4RWU|rcsb pdb:6D6X|go:"GO:0007049"(cell cycle)|dip:DIP-4385N|mint:P25294 psi-mi:"MI:0469"(intact) crc64:642D3709C0FD5682 crc64:642D3709C0FD5682 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:gp39i5OLzpajm1XnD9cYtGKD6kU559292 rogid:gp39i5OLzpajm1XnD9cYtGKD6kU559292 intact-crc:A59E7CA7FCEC6213|rigid:QAfE5VHrix65Qw2Wnpp4OGl6Kdg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41811 uniprotkb:P25294 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W intact:EBI-17244|uniprotkb:D6W1H0|ensemblfungi:YNL007C psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:sis1_yeast(display_long)|uniprotkb:YNL007C(locus name)|uniprotkb:SIS1(gene name)|psi-mi:SIS1(display_short)|uniprotkb:N2879(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319377|imex:IM-14275-498 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_014391.1|sgd:S000004952|ensemblfungi:YNL007C(gene)|ensemblfungi:YNL007C_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006413"(translational initiation)|go:"GO:0006457"(protein folding)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0035719"(tRNA import into nucleus)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070843"(misfolded protein transport)|go:"GO:0071630"(nuclear protein quality control by the ubiquitin-proteasome system)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|rcsb pdb:1C3G|rcsb pdb:2B26|rcsb pdb:4RWU|rcsb pdb:6D6X|go:"GO:0007049"(cell cycle)|dip:DIP-4385N|mint:P25294 psi-mi:"MI:0469"(intact) crc64:6A5E50BBEB02CB58 crc64:642D3709C0FD5682 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 rogid:gp39i5OLzpajm1XnD9cYtGKD6kU559292 intact-crc:108A1763152121EF|rigid:CYJDTSd+BF7g/qHh5GR03MrxkL8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25294 uniprotkb:P54783 intact:EBI-17244|uniprotkb:D6W1H0|ensemblfungi:YNL007C intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:sis1_yeast(display_long)|uniprotkb:YNL007C(locus name)|uniprotkb:SIS1(gene name)|psi-mi:SIS1(display_short)|uniprotkb:N2879(orf name) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319388|imex:IM-14275-499 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014391.1|sgd:S000004952|ensemblfungi:YNL007C(gene)|ensemblfungi:YNL007C_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006413"(translational initiation)|go:"GO:0006457"(protein folding)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0035719"(tRNA import into nucleus)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070843"(misfolded protein transport)|go:"GO:0071630"(nuclear protein quality control by the ubiquitin-proteasome system)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|rcsb pdb:1C3G|rcsb pdb:2B26|rcsb pdb:4RWU|rcsb pdb:6D6X|go:"GO:0007049"(cell cycle)|dip:DIP-4385N|mint:P25294 go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) crc64:642D3709C0FD5682 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:gp39i5OLzpajm1XnD9cYtGKD6kU559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:52CBB8EA239EA811|rigid:s3PWMPFIuExETyMIi9giYQmUUkA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14747 uniprotkb:P25296 intact:EBI-12778|uniprotkb:D6VZB7|ensemblfungi:YML057W intact:EBI-3968|uniprotkb:D6VX10|ensemblfungi:YKL190W psi-mi:pp2b2_yeast(display_long)|uniprotkb:CMP2(gene name)|psi-mi:CMP2(display_short)|uniprotkb:Calcineurin A2(gene name synonym)|uniprotkb:Calmodulin-binding protein 2(gene name synonym)|uniprotkb:CNA2(gene name synonym)|uniprotkb:YM9958.05(orf name)|uniprotkb:YML057W(locus name) psi-mi:canb_yeast(display_long)|uniprotkb:CNB1(gene name)|psi-mi:CNB1(display_short)|uniprotkb:YCN2(gene name synonym)|uniprotkb:YCNB(gene name synonym)|uniprotkb:Protein phosphatase 2B regulatory subunit(gene name synonym)|uniprotkb:Calcineurin regulatory subunit(gene name synonym)|uniprotkb:YKL190W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319399|imex:IM-14275-500 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML057W(gene)|ensemblfungi:YML057W_mRNA(transcript)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006873"(cellular ion homeostasis)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097720"(calcineurin-mediated signaling)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR041751|interpro:IPR043360|reactome:R-SCE-4086398|reactome:R-SCE-5607763|reactome:R-SCE-2871809|refseq:NP_013655.1|sgd:S000004521|mint:P14747|dip:DIP-833N refseq:NP_012731.1|sgd:S000001673|dip:DIP-510N|mint:P25296|ensemblfungi:YKL190W(gene)|ensemblfungi:YKL190W_mRNA(transcript)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006873"(cellular ion homeostasis)|go:"GO:0008597"(calcium-dependent protein serine/threonine phosphatase regulator activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015757(Calcineurin B protein)|interpro:IPR018247|reactome:R-SCE-2871809|reactome:R-SCE-4086398|reactome:R-SCE-5607763 psi-mi:"MI:0469"(intact) crc64:4A605598FD04207F crc64:6E42DB350DA05BC0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:z46FjPT6oD8QWhM8vlwDjNotLFg559292 rogid:eow/RCumgmpTh5Kfe66TOem5Sp0559292 intact-crc:B9AA998EFE565DE6|rigid:b+tcZcTYO3JBuzkobje0CXhy8WI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25296 uniprotkb:P36054 intact:EBI-3968|uniprotkb:D6VX10|ensemblfungi:YKL190W intact:EBI-14898|ensemblfungi:YKL159C|uniprotkb:D6VX40 psi-mi:canb_yeast(display_long)|uniprotkb:CNB1(gene name)|psi-mi:CNB1(display_short)|uniprotkb:YCN2(gene name synonym)|uniprotkb:YCNB(gene name synonym)|uniprotkb:Protein phosphatase 2B regulatory subunit(gene name synonym)|uniprotkb:Calcineurin regulatory subunit(gene name synonym)|uniprotkb:YKL190W(locus name) psi-mi:rcn1_yeast(display_long)|uniprotkb:RCN1(gene name)|psi-mi:RCN1(display_short)|uniprotkb:YKL159C(locus name)|uniprotkb:YKL613(orf name)|uniprotkb:DSCR1L(gene name synonym)|uniprotkb:Regulator of calcineurin 1(gene name synonym)|uniprotkb:Down syndrome candidate region 1-like protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319410|imex:IM-14275-501 author score:83.40 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012731.1|sgd:S000001673|dip:DIP-510N|mint:P25296|ensemblfungi:YKL190W(gene)|ensemblfungi:YKL190W_mRNA(transcript)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006873"(cellular ion homeostasis)|go:"GO:0008597"(calcium-dependent protein serine/threonine phosphatase regulator activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015757(Calcineurin B protein)|interpro:IPR018247|reactome:R-SCE-2871809|reactome:R-SCE-4086398|reactome:R-SCE-5607763 ensemblfungi:YKL159C(gene)|ensemblfungi:YKL159C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008597"(calcium-dependent protein serine/threonine phosphatase regulator activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030346"(protein phosphatase 2B binding)|interpro:IPR006931(Calcipressin)|interpro:IPR016523(Uncharacterised conserved protein UCP007798)|refseq:NP_012763.1|sgd:S000001642|dip:DIP-7429N|mint:P36054 psi-mi:"MI:0469"(intact) crc64:6E42DB350DA05BC0 crc64:668EA0C10D4E39AA figure legend:tables S3 and S4|author-confidence:83.40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:eow/RCumgmpTh5Kfe66TOem5Sp0559292 rogid:S+Wq+Nvw1+vOsw67ubkq+Gmesco559292 intact-crc:E791A5D8A3AEBBBC|rigid:bTHMHgHUApZZRJTeZh1IbyDzaSU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25339 uniprotkb:P25339 intact:EBI-23703|uniprotkb:D6VUC3|ensemblfungi:YGL014W intact:EBI-23703|uniprotkb:D6VUC3|ensemblfungi:YGL014W psi-mi:puf4_yeast(display_long)|uniprotkb:PUF4(gene name)|psi-mi:PUF4(display_short)|uniprotkb:YGL023(orf name)|uniprotkb:YGL014W(locus name) psi-mi:puf4_yeast(display_long)|uniprotkb:PUF4(gene name)|psi-mi:PUF4(display_short)|uniprotkb:YGL023(orf name)|uniprotkb:YGL014W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319432|imex:IM-14275-503 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011501.1|sgd:S000002982|dip:DIP-2638N|mint:P25339|ensemblfungi:YGL014W(gene)|ensemblfungi:YGL014W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:3BWT|rcsb pdb:3BX2|rcsb pdb:3BX3|rcsb pdb:4DZS|go:"GO:0003729"(mRNA binding) refseq:NP_011501.1|sgd:S000002982|dip:DIP-2638N|mint:P25339|ensemblfungi:YGL014W(gene)|ensemblfungi:YGL014W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:3BWT|rcsb pdb:3BX2|rcsb pdb:3BX3|rcsb pdb:4DZS|go:"GO:0003729"(mRNA binding) psi-mi:"MI:0469"(intact) crc64:659BA1062439F642 crc64:659BA1062439F642 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:spjnSzTKOyi8X0oMi4wOTS+72hY559292 rogid:spjnSzTKOyi8X0oMi4wOTS+72hY559292 intact-crc:083D86ED98EF61D8|rigid:Ih5iXON214AIC4drBui/5vCSOEE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25336 uniprotkb:P25584 intact:EBI-11362|ensemblfungi:YCR092C|uniprotkb:D6VR92 intact:EBI-21765|uniprotkb:D6VQW1|ensemblfungi:YCL056C psi-mi:msh3_yeast(display_long)|uniprotkb:MSH3(gene name)|psi-mi:MSH3(display_short)|uniprotkb:YCR092C(locus name)|uniprotkb:YCR92C(orf name)|uniprotkb:YCR1152(orf name)|uniprotkb:MutS protein homolog 3(gene name synonym)|uniprotkb:Mismatch-binding protein(gene name synonym) psi-mi:pex34_yeast(display_long)|uniprotkb:YCL056C(locus name)|uniprotkb:YCL56C(orf name)|uniprotkb:YCL433(orf name)|uniprotkb:PEX34(gene name)|psi-mi:PEX34(display_short)|uniprotkb:Peroxin-34(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319421|imex:IM-14275-502 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|reactome:R-SCE-5358606|ensemblfungi:YCR092C(gene)|ensemblfungi:YCR092C_mRNA(transcript)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0000735"(removal of nonhomologous ends)|go:"GO:0005737"(cytoplasm)|go:"GO:0006298"(mismatch repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0032135"(DNA insertion or deletion binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0043111"(replication fork arrest)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|refseq:NP_010016.2|sgd:S000000688|mint:P25336|dip:DIP-2422N sgd:S000000561|refseq:NP_009875.1|mint:P25584|dip:DIP-2040N|ensemblfungi:YCL056C(gene)|ensemblfungi:YCL056C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization) psi-mi:"MI:0469"(intact) crc64:1AD91C2E2F2856EF crc64:6035D449766516A6 figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+wUVIWkJoR5KHA7YuIYdskdQszE559292 rogid:IGoLOZeCbBNA4w+BG9mC/vxGfqs559292 intact-crc:1154FDFAB57DDD8F|rigid:qVn1eQlQeM5UfymEs4T1ejoK4V8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25567 uniprotkb:P25339 intact:EBI-18084|uniprotkb:D6VQX8|ensemblfungi:YCL037C intact:EBI-23703|uniprotkb:D6VUC3|ensemblfungi:YGL014W psi-mi:sro9_yeast(display_long)|uniprotkb:SRO9(gene name)|psi-mi:SRO9(display_short)|uniprotkb:YCL037C(locus name)|uniprotkb:YCL37C(orf name)|uniprotkb:Suppressor of RHO3 protein 9(gene name synonym) psi-mi:puf4_yeast(display_long)|uniprotkb:PUF4(gene name)|psi-mi:PUF4(display_short)|uniprotkb:YGL023(orf name)|uniprotkb:YGL014W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319443|imex:IM-14275-504 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009893.2|sgd:S000000542|ensemblfungi:YCL037C(gene)|ensemblfungi:YCL037C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|dip:DIP-6638N|mint:P25567 refseq:NP_011501.1|sgd:S000002982|dip:DIP-2638N|mint:P25339|ensemblfungi:YGL014W(gene)|ensemblfungi:YGL014W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:3BWT|rcsb pdb:3BX2|rcsb pdb:3BX3|rcsb pdb:4DZS|go:"GO:0003729"(mRNA binding) psi-mi:"MI:0469"(intact) crc64:B1B720D40C7B9914 crc64:659BA1062439F642 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CouwiBsK7S3Tm6CoBsu3LdWfelg559292 rogid:spjnSzTKOyi8X0oMi4wOTS+72hY559292 intact-crc:73A57B69EF12AF9B|rigid:njGpJyLl4+Mo5n6XsaySTC9/R5A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25655 uniprotkb:P25339 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-23703|uniprotkb:D6VUC3|ensemblfungi:YGL014W psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:puf4_yeast(display_long)|uniprotkb:PUF4(gene name)|psi-mi:PUF4(display_short)|uniprotkb:YGL023(orf name)|uniprotkb:YGL014W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319454|imex:IM-14275-505 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 refseq:NP_011501.1|sgd:S000002982|dip:DIP-2638N|mint:P25339|ensemblfungi:YGL014W(gene)|ensemblfungi:YGL014W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:3BWT|rcsb pdb:3BX2|rcsb pdb:3BX3|rcsb pdb:4DZS|go:"GO:0003729"(mRNA binding) psi-mi:"MI:0469"(intact) crc64:5B2AE15BCF95E009 crc64:659BA1062439F642 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:spjnSzTKOyi8X0oMi4wOTS+72hY559292 intact-crc:EEC44423D3FE61CC|rigid:h4X9p6/oie3KDks8NDrWxJtqTck false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32588 uniprotkb:P25339 intact:EBI-14231|ensemblfungi:YNL016W|uniprotkb:D6W1G2 intact:EBI-23703|uniprotkb:D6VUC3|ensemblfungi:YGL014W psi-mi:pub1_yeast(display_long)|uniprotkb:ARS consensus-binding protein ACBP-60(gene name synonym)|uniprotkb:Poly uridylate-binding protein(gene name synonym)|uniprotkb:PUB1(gene name)|psi-mi:PUB1(display_short)|uniprotkb:RNP1(gene name synonym)|uniprotkb:YNL016W(locus name)|uniprotkb:N2842(orf name) psi-mi:puf4_yeast(display_long)|uniprotkb:PUF4(gene name)|psi-mi:PUF4(display_short)|uniprotkb:YGL023(orf name)|uniprotkb:YGL014W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319465|imex:IM-14275-506 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014382.1|sgd:S000004961|ensemblfungi:YNL016W(gene)|ensemblfungi:YNL016W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043488"(regulation of mRNA stability)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034509|interpro:IPR034639|interpro:IPR035979|rcsb pdb:2LA4|rcsb pdb:3MD1|rcsb pdb:3MD3|rcsb pdb:6Z29|mint:P32588|dip:DIP-5480N refseq:NP_011501.1|sgd:S000002982|dip:DIP-2638N|mint:P25339|ensemblfungi:YGL014W(gene)|ensemblfungi:YGL014W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:3BWT|rcsb pdb:3BX2|rcsb pdb:3BX3|rcsb pdb:4DZS|go:"GO:0003729"(mRNA binding) psi-mi:"MI:0469"(intact) crc64:3B81A7735505D3CA crc64:659BA1062439F642 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8xFMuEva7leVYDKg3WOmvPtRTFk559292 rogid:spjnSzTKOyi8X0oMi4wOTS+72hY559292 intact-crc:D2AD46D6AC06A47A|rigid:7l33F3Qme4Jk+T/HZFLKIUynjsw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25339 uniprotkb:P35732 intact:EBI-23703|uniprotkb:D6VUC3|ensemblfungi:YGL014W intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C psi-mi:puf4_yeast(display_long)|uniprotkb:PUF4(gene name)|psi-mi:PUF4(display_short)|uniprotkb:YGL023(orf name)|uniprotkb:YGL014W(locus name) psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319476|imex:IM-14275-507 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011501.1|sgd:S000002982|dip:DIP-2638N|mint:P25339|ensemblfungi:YGL014W(gene)|ensemblfungi:YGL014W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:3BWT|rcsb pdb:3BX2|rcsb pdb:3BX3|rcsb pdb:4DZS|go:"GO:0003729"(mRNA binding) refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 psi-mi:"MI:0469"(intact) crc64:659BA1062439F642 crc64:05734E2D0B7389AC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:spjnSzTKOyi8X0oMi4wOTS+72hY559292 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 intact-crc:89940303AA70ED75|rigid:NU5bM7b6Jr/+XiqaBneZrZwMDFA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25339 uniprotkb:P39517 intact:EBI-23703|uniprotkb:D6VUC3|ensemblfungi:YGL014W intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C psi-mi:puf4_yeast(display_long)|uniprotkb:PUF4(gene name)|psi-mi:PUF4(display_short)|uniprotkb:YGL023(orf name)|uniprotkb:YGL014W(locus name) psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319487|imex:IM-14275-508 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011501.1|sgd:S000002982|dip:DIP-2638N|mint:P25339|ensemblfungi:YGL014W(gene)|ensemblfungi:YGL014W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:3BWT|rcsb pdb:3BX2|rcsb pdb:3BX3|rcsb pdb:4DZS|go:"GO:0003729"(mRNA binding) sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:659BA1062439F642 crc64:062CFA56DF6F2CEE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:spjnSzTKOyi8X0oMi4wOTS+72hY559292 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 intact-crc:E7D3265A6E27C09E|rigid:TJvTlndawhSzIhbnA2EZ4bimXLg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40070 uniprotkb:P25339 intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W intact:EBI-23703|uniprotkb:D6VUC3|ensemblfungi:YGL014W psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:puf4_yeast(display_long)|uniprotkb:PUF4(gene name)|psi-mi:PUF4(display_short)|uniprotkb:YGL023(orf name)|uniprotkb:YGL014W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319498|imex:IM-14275-509 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 refseq:NP_011501.1|sgd:S000002982|dip:DIP-2638N|mint:P25339|ensemblfungi:YGL014W(gene)|ensemblfungi:YGL014W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:3BWT|rcsb pdb:3BX2|rcsb pdb:3BX3|rcsb pdb:4DZS|go:"GO:0003729"(mRNA binding) psi-mi:"MI:0469"(intact) crc64:69CAC1F01D5BFA98 crc64:659BA1062439F642 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 rogid:spjnSzTKOyi8X0oMi4wOTS+72hY559292 intact-crc:1BE247DB8BF5F628|rigid:Nj1ntWBkTD0poS05E6JjJWJmJ4c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38837 uniprotkb:P25340 intact:EBI-24733|uniprotkb:D3DL82|uniprotkb:Q6Q5G1|ensemblfungi:YHR133C intact:EBI-6558|uniprotkb:D6VUC5|uniprotkb:E9P929|ensemblfungi:YGL012W psi-mi:nsg1_yeast(display_long)|uniprotkb:INSIG homolog 1(gene name synonym)|uniprotkb:YHR133C(locus name)|uniprotkb:NSG1(gene name)|psi-mi:NSG1(display_short) psi-mi:erg4_yeast(display_long)|uniprotkb:ERG4(gene name)|psi-mi:ERG4(display_short)|uniprotkb:YGL012W(locus name)|uniprotkb:YGL022(orf name)|uniprotkb:"Sterol Delta(24(28))-reductase"(gene name synonym)|uniprotkb:"C-24(28) sterol reductase"(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319520|imex:IM-14275-511 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001175|refseq:NP_012001.1|dip:DIP-2775N|mint:P38837|ensemblfungi:YHR133C(gene)|ensemblfungi:YHR133C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR025929 refseq:NP_011503.1|sgd:S000002980|mint:P25340|dip:DIP-7177N|ensemblfungi:YGL012W(gene)|ensemblfungi:YGL012W_mRNA(transcript)|go:"GO:0000246"("delta24(24-1) sterol reductase activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein)|interpro:IPR018083 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ALle5Ub0gjK3Uh+6sfIgbfa7BYw559292 rogid:BVxKi7zDnF20xAPBIry0VNTICCw559292 intact-crc:876AD9A7AC6FA51B|rigid:8S4mPZCD6uzlgmQe/dexS3trXpI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53829 uniprotkb:P25339 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-23703|uniprotkb:D6VUC3|ensemblfungi:YGL014W psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:puf4_yeast(display_long)|uniprotkb:PUF4(gene name)|psi-mi:PUF4(display_short)|uniprotkb:YGL023(orf name)|uniprotkb:YGL014W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319509|imex:IM-14275-510 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 refseq:NP_011501.1|sgd:S000002982|dip:DIP-2638N|mint:P25339|ensemblfungi:YGL014W(gene)|ensemblfungi:YGL014W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:3BWT|rcsb pdb:3BX2|rcsb pdb:3BX3|rcsb pdb:4DZS|go:"GO:0003729"(mRNA binding) psi-mi:"MI:0469"(intact) crc64:F3DBABE6AD3C7F3C crc64:659BA1062439F642 figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:spjnSzTKOyi8X0oMi4wOTS+72hY559292 intact-crc:D6118AF2F2843116|rigid:sFVDJleFLgUcLafpr5ycLngN2yA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25340 uniprotkb:Q08023 intact:EBI-6558|uniprotkb:D6VUC5|uniprotkb:E9P929|ensemblfungi:YGL012W intact:EBI-38592|uniprotkb:D6VY77|uniprotkb:Q66R51|uniprotkb:Q7LI62|ensemblfungi:YLR077W psi-mi:erg4_yeast(display_long)|uniprotkb:ERG4(gene name)|psi-mi:ERG4(display_short)|uniprotkb:YGL012W(locus name)|uniprotkb:YGL022(orf name)|uniprotkb:"Sterol Delta(24(28))-reductase"(gene name synonym)|uniprotkb:"C-24(28) sterol reductase"(gene name synonym) psi-mi:fmp25_yeast(display_long)|uniprotkb:Found in mitochondrial proteome protein 25(gene name synonym)|uniprotkb:FMP25(gene name)|psi-mi:FMP25(display_short)|uniprotkb:YLR077W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319531|imex:IM-14275-512 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011503.1|sgd:S000002980|mint:P25340|dip:DIP-7177N|ensemblfungi:YGL012W(gene)|ensemblfungi:YGL012W_mRNA(transcript)|go:"GO:0000246"("delta24(24-1) sterol reductase activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein)|interpro:IPR018083 refseq:NP_013178.1|sgd:S000004067|mint:Q08023|dip:DIP-4474N|ensemblfungi:YLR077W(gene)|ensemblfungi:YLR077W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II) psi-mi:"MI:0469"(intact) - crc64:B2EE61451F2A9948 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BVxKi7zDnF20xAPBIry0VNTICCw559292 rogid:B5w6Eh63rS1PXLWMGPtWEZ7qYMU559292 intact-crc:A3FA9FB0F53EA3D5|rigid:iV/4GH/cHkYeQCgMF6VMNfiSYrw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38328 uniprotkb:P25343 intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C intact:EBI-14490|uniprotkb:D6VR18|ensemblfungi:YCR009C psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:rv161_yeast(display_long)|uniprotkb:RVS161(gene name)|psi-mi:RVS161(display_short)|uniprotkb:END6(gene name synonym)|uniprotkb:SPE161(gene name synonym)|uniprotkb:YCR009C(locus name)|uniprotkb:YCR9C(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319542|imex:IM-14275-513 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 ensemblfungi:YCR009C(gene)|ensemblfungi:YCR009C_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005829"(cytosol)|go:"GO:0005937"(mating projection)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031097"(medial cortex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042594"(response to starvation)|go:"GO:0043332"(mating projection tip)|go:"GO:0045121"(membrane raft)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1990528"(Rvs161p-Rvs167p complex)|interpro:IPR004148(BAR)|interpro:IPR027267|go:"GO:0006970"(response to osmotic stress)|interpro:IPR037429|refseq:NP_009935.1|sgd:S000000602|mint:P25343|dip:DIP-1601N psi-mi:"MI:0469"(intact) crc64:D75C6BB8EC35EEDF crc64:B35EA00E0C900E2D figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 rogid:IdjO8RS5vcYMeGxuoPoa/5e7QJQ559292 intact-crc:BDAAA7B1DFF4D134|rigid:TN8dnv9sUpj6ozyKBc0CZIJ4vUY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39743 uniprotkb:P25343 intact:EBI-14500|uniprotkb:D6VT22|ensemblfungi:YDR388W intact:EBI-14490|uniprotkb:D6VR18|ensemblfungi:YCR009C psi-mi:rv167_yeast(display_long)|uniprotkb:D9509.8(orf name)|uniprotkb:YDR388W(locus name)|uniprotkb:RVS167(gene name)|psi-mi:RVS167(display_short) psi-mi:rv161_yeast(display_long)|uniprotkb:RVS161(gene name)|psi-mi:RVS161(display_short)|uniprotkb:END6(gene name synonym)|uniprotkb:SPE161(gene name synonym)|uniprotkb:YCR009C(locus name)|uniprotkb:YCR9C(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319553|imex:IM-14275-514 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR388W(gene)|ensemblfungi:YDR388W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006897"(endocytosis)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031097"(medial cortex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR036028|go:"GO:1990528"(Rvs161p-Rvs167p complex)|refseq:NP_010676.1|sgd:S000002796|mint:P39743|dip:DIP-770N ensemblfungi:YCR009C(gene)|ensemblfungi:YCR009C_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005829"(cytosol)|go:"GO:0005937"(mating projection)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031097"(medial cortex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042594"(response to starvation)|go:"GO:0043332"(mating projection tip)|go:"GO:0045121"(membrane raft)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1990528"(Rvs161p-Rvs167p complex)|interpro:IPR004148(BAR)|interpro:IPR027267|go:"GO:0006970"(response to osmotic stress)|interpro:IPR037429|refseq:NP_009935.1|sgd:S000000602|mint:P25343|dip:DIP-1601N psi-mi:"MI:0469"(intact) crc64:3F0AB53EBCC95A5B crc64:B35EA00E0C900E2D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:w3CZzhpvanHbodoFFlzkAHnsQyA559292 rogid:IdjO8RS5vcYMeGxuoPoa/5e7QJQ559292 intact-crc:0593E8BBDF05495F|rigid:pmrWC5Yh51mm5vnCLZZn8v3jbwk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04322 uniprotkb:P25343 intact:EBI-27427|uniprotkb:D6W016|ensemblfungi:YMR192W intact:EBI-14490|uniprotkb:D6VR18|ensemblfungi:YCR009C psi-mi:gyl1_yeast(display_long)|uniprotkb:YMR192W(locus name)|uniprotkb:YM9646.04(orf name)|uniprotkb:GYL1(gene name)|psi-mi:GYL1(display_short)|uniprotkb:APP2(gene name synonym)|uniprotkb:GYP5-like protein 1(gene name synonym) psi-mi:rv161_yeast(display_long)|uniprotkb:RVS161(gene name)|psi-mi:RVS161(display_short)|uniprotkb:END6(gene name synonym)|uniprotkb:SPE161(gene name synonym)|uniprotkb:YCR009C(locus name)|uniprotkb:YCR9C(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319564|imex:IM-14275-515 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q04322|refseq:NP_013917.1|sgd:S000004804|dip:DIP-2891N|ensemblfungi:YMR192W(gene)|ensemblfungi:YMR192W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0017157"(regulation of exocytosis)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969 ensemblfungi:YCR009C(gene)|ensemblfungi:YCR009C_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005829"(cytosol)|go:"GO:0005937"(mating projection)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031097"(medial cortex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042594"(response to starvation)|go:"GO:0043332"(mating projection tip)|go:"GO:0045121"(membrane raft)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1990528"(Rvs161p-Rvs167p complex)|interpro:IPR004148(BAR)|interpro:IPR027267|go:"GO:0006970"(response to osmotic stress)|interpro:IPR037429|refseq:NP_009935.1|sgd:S000000602|mint:P25343|dip:DIP-1601N psi-mi:"MI:0469"(intact) - crc64:B35EA00E0C900E2D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:JXXEUKwB+ysZExb+8We4yeNrftM559292 rogid:IdjO8RS5vcYMeGxuoPoa/5e7QJQ559292 intact-crc:FDB7BBD3265F92E3|rigid:6nRbH8N0hxHV/7T5pUUzxcvWPj4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25386 uniprotkb:P15496 intact:EBI-20157|uniprotkb:P89892|uniprotkb:Q07380|uniprotkb:E9PAG8|uniprotkb:D6VRT8|ensemblfungi:YDL058W intact:EBI-8902|ensemblfungi:YPL117C|uniprotkb:D6W3Q1 psi-mi:uso1_yeast(display_long)|uniprotkb:USO1(gene name)|psi-mi:USO1(display_short)|uniprotkb:INT1(gene name synonym)|uniprotkb:YDL058W(locus name) psi-mi:idi1_yeast(display_long)|uniprotkb:Isopentenyl pyrophosphate isomerase(gene name synonym)|uniprotkb:IDI1(gene name)|psi-mi:IDI1(display_short)|uniprotkb:BOT2(gene name synonym)|uniprotkb:YPL117C(locus name)|uniprotkb:LPH10C(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319575|imex:IM-14275-516 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010225.1|sgd:S000002216|ensemblfungi:YDL058W(gene)|ensemblfungi:YDL058W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005795"(Golgi stack)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045056"(transcytosis)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0061025"(membrane fusion)|interpro:IPR006953(Uso1/p115 like vesicle tethering protein, head region)|interpro:IPR006955(Uso1/p115 like vesicle tethering protein, C-terminal)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:6LST|rcsb pdb:6LSU|reactome:R-SCE-204005|reactome:R-SCE-6807878|mint:P25386|dip:DIP-6815N ensemblfungi:YPL117C(gene)|ensemblfungi:YPL117C_mRNA(transcript)|go:"GO:0004452"(isopentenyl-diphosphate delta-isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009240"(isopentenyl diphosphate biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0045337"(farnesyl diphosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050992"(dimethylallyl diphosphate biosynthetic process)|reactome:R-SCE-191273|refseq:NP_015208.1|sgd:S000006038|interpro:IPR011876(Isopentenyl-diphosphate delta-isomerase, type 1)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|mint:P15496 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oEN6SEosatK8jdPa7+Bvc1ibDK8559292 rogid:KQ9qSb2grQ4DQip7atYPeCwp5QM559292 intact-crc:618BB0395D828402|rigid:UBKft9L8ltvLUmRe/uMFUCwKPmA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25386 uniprotkb:P25386 intact:EBI-20157|uniprotkb:P89892|uniprotkb:Q07380|uniprotkb:E9PAG8|uniprotkb:D6VRT8|ensemblfungi:YDL058W intact:EBI-20157|uniprotkb:P89892|uniprotkb:Q07380|uniprotkb:E9PAG8|uniprotkb:D6VRT8|ensemblfungi:YDL058W psi-mi:uso1_yeast(display_long)|uniprotkb:USO1(gene name)|psi-mi:USO1(display_short)|uniprotkb:INT1(gene name synonym)|uniprotkb:YDL058W(locus name) psi-mi:uso1_yeast(display_long)|uniprotkb:USO1(gene name)|psi-mi:USO1(display_short)|uniprotkb:INT1(gene name synonym)|uniprotkb:YDL058W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319586|imex:IM-14275-517 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010225.1|sgd:S000002216|ensemblfungi:YDL058W(gene)|ensemblfungi:YDL058W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005795"(Golgi stack)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045056"(transcytosis)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0061025"(membrane fusion)|interpro:IPR006953(Uso1/p115 like vesicle tethering protein, head region)|interpro:IPR006955(Uso1/p115 like vesicle tethering protein, C-terminal)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:6LST|rcsb pdb:6LSU|reactome:R-SCE-204005|reactome:R-SCE-6807878|mint:P25386|dip:DIP-6815N refseq:NP_010225.1|sgd:S000002216|ensemblfungi:YDL058W(gene)|ensemblfungi:YDL058W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005795"(Golgi stack)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045056"(transcytosis)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0061025"(membrane fusion)|interpro:IPR006953(Uso1/p115 like vesicle tethering protein, head region)|interpro:IPR006955(Uso1/p115 like vesicle tethering protein, C-terminal)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:6LST|rcsb pdb:6LSU|reactome:R-SCE-204005|reactome:R-SCE-6807878|mint:P25386|dip:DIP-6815N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oEN6SEosatK8jdPa7+Bvc1ibDK8559292 rogid:oEN6SEosatK8jdPa7+Bvc1ibDK8559292 intact-crc:876CED50E44DFB75|rigid:Y19YIsNnkF8mCZCOlnT/fqOrRUY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25454 uniprotkb:P25454 intact:EBI-14709|uniprotkb:D3DM03|ensemblfungi:YER095W intact:EBI-14709|uniprotkb:D3DM03|ensemblfungi:YER095W psi-mi:rad51_yeast(display_long)|uniprotkb:YER095W(locus name)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short) psi-mi:rad51_yeast(display_long)|uniprotkb:YER095W(locus name)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319608|imex:IM-14275-519 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000897|ensemblfungi:YER095W(gene)|go:"GO:0042802"(identical protein binding)|go:"GO:0042148"(strand invasion)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|rcsb pdb:1SZP|rcsb pdb:3LDA|reactome:R-SCE-5693616|ensemblfungi:YER095W_mRNA(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000709"(meiotic joint molecule formation)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0030491"(heteroduplex formation)|refseq:NP_011021.3|dip:DIP-195N|mint:P25454 sgd:S000000897|ensemblfungi:YER095W(gene)|go:"GO:0042802"(identical protein binding)|go:"GO:0042148"(strand invasion)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|rcsb pdb:1SZP|rcsb pdb:3LDA|reactome:R-SCE-5693616|ensemblfungi:YER095W_mRNA(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000709"(meiotic joint molecule formation)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0030491"(heteroduplex formation)|refseq:NP_011021.3|dip:DIP-195N|mint:P25454 psi-mi:"MI:0469"(intact) crc64:66561B60122A39A2 crc64:66561B60122A39A2 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jag7vb8ZabIsqGQYBIdF3HVkziY559292 rogid:jag7vb8ZabIsqGQYBIdF3HVkziY559292 intact-crc:E915D74458856817|rigid:nq226hB+BQYHG+R68xW9ZLJ4YIU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04410 uniprotkb:P25386 intact:EBI-32083|uniprotkb:D6VTD8|ensemblfungi:YDR517W intact:EBI-20157|uniprotkb:P89892|uniprotkb:Q07380|uniprotkb:E9PAG8|uniprotkb:D6VRT8|ensemblfungi:YDL058W psi-mi:grh1_yeast(display_long)|uniprotkb:GRH1(gene name)|psi-mi:GRH1(display_short)|uniprotkb:YDR517W(locus name) psi-mi:uso1_yeast(display_long)|uniprotkb:USO1(gene name)|psi-mi:USO1(display_short)|uniprotkb:INT1(gene name synonym)|uniprotkb:YDL058W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319597|imex:IM-14275-518 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010805.1|sgd:S000002925|dip:DIP-6613N|mint:Q04410|ensemblfungi:YDR517W(gene)|ensemblfungi:YDR517W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0009306"(protein secretion)|go:"GO:0031090"(organelle membrane)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR007583(GRASP55/65)|interpro:IPR024958|interpro:IPR036034|rcsb pdb:6G8Y|reactome:R-SCE-162658|reactome:R-SCE-204005 refseq:NP_010225.1|sgd:S000002216|ensemblfungi:YDL058W(gene)|ensemblfungi:YDL058W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005795"(Golgi stack)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045056"(transcytosis)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0061025"(membrane fusion)|interpro:IPR006953(Uso1/p115 like vesicle tethering protein, head region)|interpro:IPR006955(Uso1/p115 like vesicle tethering protein, C-terminal)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:6LST|rcsb pdb:6LSU|reactome:R-SCE-204005|reactome:R-SCE-6807878|mint:P25386|dip:DIP-6815N psi-mi:"MI:0469"(intact) crc64:A7CE62DFE4631214 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Tj4Jf1BeT57ROzFoNoi+g9GLuYk559292 rogid:oEN6SEosatK8jdPa7+Bvc1ibDK8559292 intact-crc:3E1FF8BB49AA188C|rigid:r0WE9YJmHuFXHO+tJ/80LKk+v5w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25491 uniprotkb:P25491 intact:EBI-10420|ensemblfungi:YNL064C|uniprotkb:D6W1B6 intact:EBI-10420|ensemblfungi:YNL064C|uniprotkb:D6W1B6 psi-mi:mas5_yeast(display_long)|uniprotkb:YDJ1(gene name)|psi-mi:YDJ1(display_short)|uniprotkb:MAS5(gene name synonym)|uniprotkb:YNL064C(locus name)|uniprotkb:N2418(orf name)|uniprotkb:YNL2418C(orf name)|uniprotkb:Yeast dnaJ protein 1(gene name synonym) psi-mi:mas5_yeast(display_long)|uniprotkb:YDJ1(gene name)|psi-mi:YDJ1(display_short)|uniprotkb:MAS5(gene name synonym)|uniprotkb:YNL064C(locus name)|uniprotkb:N2418(orf name)|uniprotkb:YNL2418C(orf name)|uniprotkb:Yeast dnaJ protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319619|imex:IM-14275-520 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014335.1|sgd:S000005008|ensemblfungi:YNL064C_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006458"('de novo' protein folding)|ensemblfungi:YNL064C(gene)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0009408"(response to heat)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0035719"(tRNA import into nucleus)|go:"GO:0042026"(protein refolding)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0072380"(TRC complex)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|rcsb pdb:1NLT|rcsb pdb:1XAO|rcsb pdb:5VSO|reactome:R-SCE-3371497|interpro:IPR018253|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|dip:DIP-2251N|mint:P25491 refseq:NP_014335.1|sgd:S000005008|ensemblfungi:YNL064C_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006458"('de novo' protein folding)|ensemblfungi:YNL064C(gene)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0009408"(response to heat)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0035719"(tRNA import into nucleus)|go:"GO:0042026"(protein refolding)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0072380"(TRC complex)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|rcsb pdb:1NLT|rcsb pdb:1XAO|rcsb pdb:5VSO|reactome:R-SCE-3371497|interpro:IPR018253|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|dip:DIP-2251N|mint:P25491 psi-mi:"MI:0469"(intact) crc64:E4539F3618DD9CF2 crc64:E4539F3618DD9CF2 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oFw3ARy6McOdWBXpq0WK6si5GYw559292 rogid:oFw3ARy6McOdWBXpq0WK6si5GYw559292 intact-crc:5447DC993C99EF72|rigid:F1C8fUuO7u3OfgrOqAEE+lGYxbg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53054 uniprotkb:P25554 intact:EBI-2050563|uniprotkb:D6VV72|ensemblfungi:YGL262W intact:EBI-21678|uniprotkb:P87008|uniprotkb:D6VR02|ensemblfungi:YCL010C psi-mi:ygzg_yeast(display_long)|uniprotkb:NRB175(orf name)|uniprotkb:YGL262W(locus name) psi-mi:sgf29_yeast(display_long)|uniprotkb:YCL010C(locus name)|uniprotkb:YCL10C(orf name)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:29 kDa SAGA-associated factor(gene name synonym)|uniprotkb:SAGA histone acetyltransferase complex 29 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319630|imex:IM-14275-521 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003231|refseq:NP_011252.1|mint:P53054|interpro:IPR035237|ensemblfungi:YGL262W(gene)|ensemblfungi:YGL262W_mRNA(transcript) refseq:NP_009917.1|sgd:S000000516|mint:P25554|dip:DIP-4871N|interpro:IPR002999(Tudor)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|rcsb pdb:3MP1|rcsb pdb:3MP6|rcsb pdb:3MP8|ensemblfungi:YCL010C(gene)|ensemblfungi:YCL010C_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0043971"(histone H3-K18 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0072742"(SAGA complex localization to transcription regulatory region) psi-mi:"MI:0469"(intact) - crc64:4DD51E36BB01C073 figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dcIvNuLjbLdnZM0WVuLPl6wq65Q559292 rogid:Y76gVxVXjP5X1WclkIVqTZEhjsk559292 intact-crc:DEB567C77DBCA791|rigid:pCal8s0Q2t8ouW/W96KZS6Q1DOs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12157 uniprotkb:P25559 intact:EBI-29698|uniprotkb:D6VRX9|ensemblfungi:YDL008W intact:EBI-5661|uniprotkb:Q8NIM7|uniprotkb:D6VQZ8|ensemblfungi:YCL016C psi-mi:apc11_yeast(display_long)|uniprotkb:D2900(orf name)|uniprotkb:YDL008W(locus name)|uniprotkb:APC11(gene name)|psi-mi:APC11(display_short) psi-mi:dcc1_yeast(display_long)|uniprotkb:DCC1(gene name)|psi-mi:DCC1(display_short)|uniprotkb:YCL016C(locus name)|uniprotkb:YCL16C(orf name)|uniprotkb:Defective in sister chromatid cohesion protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319641|imex:IM-14275-522 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002166|refseq:NP_010276.3|dip:DIP-1130N|mint:Q12157|ensemblfungi:YDL008W(gene)|ensemblfungi:YDL008W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024991|reactome:R-SCE-983168 refseq:NP_009913.2|sgd:S000000521|dip:DIP-2088N|mint:P25559|ensemblfungi:YCL016C(gene)|ensemblfungi:YCL016C_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|interpro:IPR019128|rcsb pdb:5MSM|rcsb pdb:5MSN|rcsb pdb:5OKC|rcsb pdb:5OKI|rcsb pdb:6S1C|rcsb pdb:6S2E|rcsb pdb:6S2F psi-mi:"MI:0469"(intact) crc64:99F8E8C6BC841934 crc64:DEA59A7BBB337282 figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4Y87RTVTCmu4TYy0VhAuAcCASk0559292 rogid:haLXgwBpTkhM0Mb55FFsMzdg3JM559292 intact-crc:D7BAC6822D65E874|rigid:iIU7evo+u4TImoFZJhwxE7hCGOw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25569 uniprotkb:P25569 intact:EBI-21727|uniprotkb:D6VQX6|ensemblfungi:YCL039W intact:EBI-21727|uniprotkb:D6VQX6|ensemblfungi:YCL039W psi-mi:gid7_yeast(display_long)|uniprotkb:YCL039W(locus name)|uniprotkb:YCL39W(orf name)|uniprotkb:YCL311(orf name)|uniprotkb:GID7(gene name)|psi-mi:GID7(display_short)|uniprotkb:MOH2(gene name synonym) psi-mi:gid7_yeast(display_long)|uniprotkb:YCL039W(locus name)|uniprotkb:YCL39W(orf name)|uniprotkb:YCL311(orf name)|uniprotkb:GID7(gene name)|psi-mi:GID7(display_short)|uniprotkb:MOH2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319652|imex:IM-14275-523 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009891.1|sgd:S000000544|mint:P25569|dip:DIP-4496N|ensemblfungi:YCL039W(gene)|ensemblfungi:YCL039W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045721"(negative regulation of gluconeogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:7NSB refseq:NP_009891.1|sgd:S000000544|mint:P25569|dip:DIP-4496N|ensemblfungi:YCL039W(gene)|ensemblfungi:YCL039W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045721"(negative regulation of gluconeogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:7NSB psi-mi:"MI:0469"(intact) crc64:558D538AD27E3B71 crc64:558D538AD27E3B71 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rCMpjSf8pr6RxTDA1hqylCHiesc559292 rogid:rCMpjSf8pr6RxTDA1hqylCHiesc559292 intact-crc:AB7D5C5C0ADA882A|rigid:eLxNCODLzuHapnHc3jF4t2aTmic false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25583 uniprotkb:P53829 intact:EBI-9509|ensemblfungi:YCL055W|uniprotkb:D6VQW2 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W psi-mi:kar4_yeast(display_long)|uniprotkb:YCL432(orf name)|uniprotkb:YCL55W(orf name)|uniprotkb:YCL055W(locus name)|uniprotkb:KAR4(gene name)|psi-mi:KAR4(display_short) psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319663|imex:IM-14275-524 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009876.1|sgd:S000000560|ensemblfungi:YCL055W(gene)|ensemblfungi:YCL055W_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007329"(positive regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0080009"(mRNA methylation)|interpro:IPR007757(MT-A70)|mint:P25583|dip:DIP-1401N refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 psi-mi:"MI:0469"(intact) crc64:B54A4E2E6563EC81 crc64:F3DBABE6AD3C7F3C figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:D6sGUzXag8WgC4/E8YrlqBAw1fU559292 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 intact-crc:00DAACDE4B8C0AFD|rigid:Cgz3MCleEy025CZpF52AO8qxVCs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43601 uniprotkb:P25591 intact:EBI-22968|uniprotkb:D6VTQ1|ensemblfungi:YFR021W intact:EBI-21800|uniprotkb:P25590|uniprotkb:D6VQV5|ensemblfungi:YCL063W psi-mi:atg18_yeast(display_long)|uniprotkb:NMR1(gene name synonym)|uniprotkb:YFR021W(locus name)|uniprotkb:ATG18(gene name)|psi-mi:ATG18(display_short)|uniprotkb:AUT10(gene name synonym)|uniprotkb:CVT18(gene name synonym)|uniprotkb:SVP1(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 18(gene name synonym)|uniprotkb:Swollen vacuole phenotype protein 1(gene name synonym)|uniprotkb:Needed for premeiotic replication protein 1(gene name synonym) psi-mi:vac17_yeast(display_long)|uniprotkb:YCL063W(locus name)|uniprotkb:YCL63W/YCL62W(orf name)|uniprotkb:VAC17(gene name)|psi-mi:VAC17(display_short)|uniprotkb:Vacuole-specific MYO2 receptor VAC17(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319674|imex:IM-14275-525 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_444297.1|sgd:S000001917|dip:DIP-5185N|mint:P43601|ensemblfungi:YFR021W(gene)|ensemblfungi:YFR021W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006497"(protein lipidation)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061908"(phagophore)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070772"(PAS complex)|go:"GO:0071944"(cell periphery)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:6KYB|reactome:R-SCE-1632852 sgd:S000000568|refseq:NP_009870.1|mint:P25591|dip:DIP-2065N|ensemblfungi:YCL063W(gene)|ensemblfungi:YCL063W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|interpro:IPR035293 psi-mi:"MI:0469"(intact) crc64:06B2DFAF842AE933 crc64:7F14A3A0BFE9571B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dUJPRtNzoRFY/sp9LSteu2xC13A559292 rogid:eOkU5SidNp4gs6B5BwPDReENlQA559292 intact-crc:7A4A179F6A77A147|rigid:i87vmE+YMptv90n+IK6Kgo1JA8E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25619 uniprotkb:P10823 intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319685|imex:IM-14275-526 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) crc64:260474A481D29AC5 crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:12BD0216D3FDBEC0|rigid:oIWF1wybgdj/NDRZNc1SKGCJaX8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25619 uniprotkb:P14359 intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319696|imex:IM-14275-527 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) crc64:260474A481D29AC5 crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:7728711E55F81E2E|rigid:vURvBsq35sPyEJW92Fd6rr3S78A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25619 uniprotkb:P19807 intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319707|imex:IM-14275-528 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) crc64:260474A481D29AC5 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:3A74411D27410DAE|rigid:GEzS5hrz+q+8qXF2FpnPAa/beZY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25619 uniprotkb:P25619 intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319718|imex:IM-14275-529 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) crc64:260474A481D29AC5 crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:930630A6FA7680EE|rigid:FFuZclO9C5sy34R3mHD4VSjxPaI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:P25619 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319729|imex:IM-14275-530 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) crc64:8B7F009521F72C15 crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:E784E7A0F28B11AA|rigid:hs2aKxuP9Kugyl1zkSJTZ3AZFX8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32458 uniprotkb:P25619 intact:EBI-4178|uniprotkb:D6VWP6|ensemblfungi:YJR076C intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:cdc11_yeast(display_long)|uniprotkb:CDC11(gene name)|psi-mi:CDC11(display_short)|uniprotkb:PSL9(gene name synonym)|uniprotkb:YJR076C(locus name)|uniprotkb:J1833(orf name) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319751|imex:IM-14275-532 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012610.1|sgd:S000003837|dip:DIP-1656N|mint:P32458|ensemblfungi:YJR076C(gene)|ensemblfungi:YJR076C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:5AR1 refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) crc64:5CFFD4CD1F6C57D4 crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:KRcNMx6EOTmvHb+6u15UrVoyb3s559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:08B2BE6129F1BDF4|rigid:cSoutLJDv79Lm7o1+TC0VrH6tvE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25619 uniprotkb:P30605 intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C intact:EBI-2050956|uniprotkb:D6VTB9|ensemblfungi:YDR497C psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:itr1_yeast(display_long)|uniprotkb:D9719.3(orf name)|uniprotkb:YDR497C(locus name)|uniprotkb:ITR1(gene name)|psi-mi:ITR1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319740|imex:IM-14275-531 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 refseq:NP_010785.1|sgd:S000002905|dip:DIP-7406N|mint:P30605|ensemblfungi:YDR497C(gene)|ensemblfungi:YDR497C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:260474A481D29AC5 - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 rogid:GgtK4YFe7ZCZcmVpV5q1KY2F0Ds559292 intact-crc:A1D855A466BE4AD0|rigid:DHHWYj7wIReTu4+xPbHuoYbnOiM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:P25619 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319762|imex:IM-14275-533 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) - crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:47C5DC83D63874B6|rigid:L+kLEioZcjTqlLYnKLfTltYNJGY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32568 uniprotkb:P25619 intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319773|imex:IM-14275-534 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) - crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:E401FDB5409984E2|rigid:LQ1s4TrAF7wQYpFYhcbmTbc7nME false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33413 uniprotkb:P25619 intact:EBI-2060312|uniprotkb:D3DKP5|ensemblfungi:YHL016C intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:dur3_yeast(display_long)|uniprotkb:DUR3(gene name)|psi-mi:DUR3(display_short)|uniprotkb:YHL016C(locus name) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319784|imex:IM-14275-535 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031155|refseq:NP_011847.1|sgd:S000001008|interpro:IPR001734(Na+/solute symporter)|interpro:IPR038377|mint:P33413|ensemblfungi:YHL016C(gene)|ensemblfungi:YHL016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0015204"(urea transmembrane transporter activity)|go:"GO:0015489"(putrescine transmembrane transporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015840"(urea transport)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery) refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) - crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oTFsdtOngA3q5wCbhK/fpVlIsz0559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:1F704F4949D35AF2|rigid:rwqX3vHzucVCjSMUT23cEdW/ap4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P25619 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319795|imex:IM-14275-536 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) - crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:7C2BD7F15AD1CD74|rigid:K8fHtgk2ULI/sh36HrPi+5m48Uw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:P25619 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319806|imex:IM-14275-537 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) - crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:5E7117A9CDF31620|rigid:7KoAso1X/+66IDV/f/58ZTv72sY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38695 uniprotkb:P25619 intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319817|imex:IM-14275-538 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) crc64:6906721BAC1A5F87 crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:D780ACDBB9ED2D53|rigid:UWE9KT0hcFWa/8bNly/a9L1KNaA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25619 uniprotkb:P49573 intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C intact:EBI-5261|uniprotkb:D6W4C2|ensemblfungi:YPR124W psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:ctr1_yeast(display_long)|uniprotkb:CTR1(gene name)|psi-mi:CTR1(display_short)|uniprotkb:P9642.3(orf name)|uniprotkb:YPR124W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319828|imex:IM-14275-539 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 refseq:NP_015449.1|sgd:S000006328|dip:DIP-6447N|mint:P49573|ensemblfungi:YPR124W(gene)|ensemblfungi:YPR124W_mRNA(transcript)|go:"GO:0005375"(copper ion transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0015677"(copper ion import)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007274(Ctr copper transporter) psi-mi:"MI:0469"(intact) crc64:260474A481D29AC5 crc64:569C9CB19C1117E8 figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 rogid:ZBHA8DsRaWE20ANtlw2JSfjD8uQ559292 intact-crc:00EA923EB2490A55|rigid:hK+M4Fr2yI3erfiphQSLJgCO49U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53283 uniprotkb:P25619 intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319850|imex:IM-14275-541 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) - crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:9356A9CAADBBEAB3|rigid:GI9MWn/arYYNQHfp9sqFRR6DE/s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53278 uniprotkb:P25619 intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319839|imex:IM-14275-540 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome) refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) crc64:D482327C9274C026 crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:623608292FD39580|rigid:5BIWAEGLqudCwfSQw4+17zl7AK0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02201 uniprotkb:P25619 intact:EBI-12636|uniprotkb:D6VXT9|ensemblfungi:YKR003W intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:osh6_yeast(display_long)|uniprotkb:YK102(orf name)|uniprotkb:YKR003W(locus name)|uniprotkb:OSH6(gene name)|psi-mi:OSH6(display_short) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319861|imex:IM-14275-542 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0015914"(phospholipid transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0120015"(sterol transfer activity)|rcsb pdb:4B2Z|rcsb pdb:4PH7|reactome:R-SCE-1482801|reactome:R-SCE-192105|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensemblfungi:YKR003W(gene)|ensemblfungi:YKR003W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|refseq:NP_012928.1|sgd:S000001711|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|mint:Q02201 refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) - crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aOZdSdLn96ns0C9w9E3r62iNyYo559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:ACA04E8B16554C78|rigid:SCKhmP8yhv5P4qfAwqZ+s5P8B9Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02785 uniprotkb:P25619 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319872|imex:IM-14275-543 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) - crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:DAAB4C679F3525FC|rigid:YY4mzRauIF2zBeMcrw1OKsK9ivQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03497 uniprotkb:P25619 intact:EBI-18285|uniprotkb:D3DKQ8|ensemblfungi:YHL007C intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:ste20_yeast(display_long)|uniprotkb:STE20(gene name)|psi-mi:STE20(display_short)|uniprotkb:YHL007C(locus name) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319883|imex:IM-14275-544 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011856.1|sgd:S000000999|ensemblfungi:YHL007C(gene)|ensemblfungi:YHL007C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|reactome:R-SCE-389359|interpro:IPR036936|reactome:R-SCE-5627123|reactome:R-SCE-5687128|reactome:R-SCE-9013405|reactome:R-SCE-9013406|rcsb pdb:2KYM|rcsb pdb:2LCS|rcsb pdb:2RQW|reactome:R-SCE-2029482|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035376"(sterol import)|go:"GO:0035404"(histone-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044025"("histone kinase activity (H2B-S14 specific)")|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|dip:DIP-712N|mint:Q03497 refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) crc64:69C1C12F5B87733C crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ammX6PwJCeyVjNxJ2UJUBrZt9mM559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:3ACA52B456992532|rigid:cWQZJGm5Bz8fn5imAEn1rLVe6g8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25619 uniprotkb:Q03640 intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319894|imex:IM-14275-545 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) crc64:260474A481D29AC5 crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:949B494A368572A1|rigid:/7XMkRRblEQUWpV3W6RAXn0y1QU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06179 uniprotkb:P25619 intact:EBI-32551|uniprotkb:D6VZ88|ensemblfungi:YLR454W intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:fmp27_yeast(display_long)|uniprotkb:FMP27(gene name)|psi-mi:FMP27(display_short)|uniprotkb:Found in mitochondrial proteome protein 27(gene name synonym)|uniprotkb:YLR454W(locus name) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319905|imex:IM-14275-546 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013559.1|sgd:S000004446|dip:DIP-3005N|mint:Q06179|ensemblfungi:YLR454W(gene)|ensemblfungi:YLR454W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|interpro:IPR019409|interpro:IPR019415|interpro:IPR019439|interpro:IPR019441|interpro:IPR019443|interpro:IPR019449 refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) - crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:sTubG6TouVnqDZ9kBcxn06d8d9Q559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:88FE5A4E3A6885CF|rigid:zTerpNuStVqx2RhhXB4kwIU0OPs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25619 uniprotkb:Q08967 intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C intact:EBI-36673|uniprotkb:D6W3E9|ensemblfungi:YPL221W psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:flc1_yeast(display_long)|uniprotkb:FAD transporter 1(gene name synonym)|uniprotkb:FLC1(gene name)|psi-mi:FLC1(display_short)|uniprotkb:TRP-like ion channel protein FLC1(gene name synonym)|uniprotkb:Heme utilization factor 1(gene name synonym)|uniprotkb:Bypass of PAM1 protein 1(gene name synonym)|uniprotkb:HUF1(gene name synonym)|uniprotkb:YPL221W(locus name)|uniprotkb:BOP1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319927|imex:IM-14275-548 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 refseq:NP_015103.1|sgd:S000006142|mint:Q08967|dip:DIP-3965N|ensemblfungi:YPL221W(gene)|ensemblfungi:YPL221W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055085"(transmembrane transport)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241 psi-mi:"MI:0469"(intact) crc64:260474A481D29AC5 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 rogid:r6CcZGEjxHUk2w0iBUBvnAPaFd4559292 intact-crc:630C1054E8848C9D|rigid:nKwYfmANi3VzfINluSrwhwoMqB0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P25619 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319916|imex:IM-14275-547 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) - crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:D480BE19D178403C|rigid:gl2croUd09IX2Kdnfwb72ufa8yo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12256 uniprotkb:P25619 intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319938|imex:IM-14275-549 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) - crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:27434FDF0703F9D7|rigid:MsE3ZYecMYfL1IswYLHTn3alQH4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3E756 uniprotkb:P25619 intact:EBI-2044812|uniprotkb:D6VPX0|ensemblfungi:YBL029C-A intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:yb029_yeast(display_long)|uniprotkb:YBL029C-A(locus name) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319949|imex:IM-14275-550 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000007591|refseq:NP_076874.1|mint:Q3E756|ensemblfungi:YBL029C-A(gene)|ensemblfungi:YBL029C-A_mRNA(transcript)|go:"GO:0005886"(plasma membrane) refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) - crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Y9LDkESr65DK5SLFNTw1dBKeqPc559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:BC9C726B63354465|rigid:pCrYqQdebzgUkJHHBX7hIB1PM9c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99271 uniprotkb:P25619 intact:EBI-11808|ensemblfungi:YLR138W|uniprotkb:D6VYD3 intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:nah1_yeast(display_long)|uniprotkb:NHA1(gene name)|psi-mi:NHA1(display_short)|uniprotkb:L3149(orf name)|uniprotkb:L9606.4(orf name)|uniprotkb:YLR138W(locus name) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319960|imex:IM-14275-551 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0045121"(membrane raft)|go:"GO:0097623"(potassium ion export across plasma membrane)|interpro:IPR004712(Fungal Na+/H+ antiporter)|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR013928(Alkali metal cation/H+ antiporter Nha1, C-terminal)|interpro:IPR032516|interpro:IPR038770|rcsb pdb:6QK8|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|ensemblfungi:YLR138W(gene)|ensemblfungi:YLR138W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0015079"(potassium ion transmembrane transporter activity)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0015491"("cation:cation antiporter activity")|go:"GO:0016021"(integral component of membrane)|refseq:NP_013239.1|sgd:S000004128|dip:DIP-6364N|mint:Q99271 refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) crc64:AD0B86D483DCDD89 crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:88+AXuO37BRzdlHWPDvWAESQM+M559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:B9958FAC4C0988B5|rigid:GwLbOw/JHEyJK29+S17tMRKW1SQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25623 uniprotkb:P10823 intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319971|imex:IM-14275-552 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) crc64:6F35C8F1562E41CC crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:E3E55106D5F9EC2C|rigid:Q2nLwmJHEfXV3GdHcTdIbsohTZM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25623 uniprotkb:P19807 intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319982|imex:IM-14275-553 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) crc64:6F35C8F1562E41CC - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:CB2EC57D29655F42|rigid:2p1WOlApSZC0puQqy4/bLEPYlS8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25623 uniprotkb:P25623 intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6319993|imex:IM-14275-554 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:6F35C8F1562E41CC crc64:6F35C8F1562E41CC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 intact-crc:D9FFB4EA68AAAA3E|rigid:pUxjWtFwJvbqE4jYymW6fiTwtko false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25623 uniprotkb:P32458 intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C intact:EBI-4178|uniprotkb:D6VWP6|ensemblfungi:YJR076C psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:cdc11_yeast(display_long)|uniprotkb:CDC11(gene name)|psi-mi:CDC11(display_short)|uniprotkb:PSL9(gene name synonym)|uniprotkb:YJR076C(locus name)|uniprotkb:J1833(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320004|imex:IM-14275-555 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 refseq:NP_012610.1|sgd:S000003837|dip:DIP-1656N|mint:P32458|ensemblfungi:YJR076C(gene)|ensemblfungi:YJR076C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:5AR1 psi-mi:"MI:0469"(intact) crc64:6F35C8F1562E41CC crc64:5CFFD4CD1F6C57D4 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 rogid:KRcNMx6EOTmvHb+6u15UrVoyb3s559292 intact-crc:B313693DBD29C5C8|rigid:RRAGy44KFkpw+/vdOiqe5RQ+QrA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25623 uniprotkb:P32660 intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320015|imex:IM-14275-556 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) psi-mi:"MI:0469"(intact) crc64:6F35C8F1562E41CC crc64:3CC3FBA8ADDE8960 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 intact-crc:33994463EEA96065|rigid:/N5npkX8GFN+aXx23hnFN5SEXtM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25623 uniprotkb:P35735 intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320026|imex:IM-14275-557 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) crc64:6F35C8F1562E41CC - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:C788D7DDC629B548|rigid:jeLPHV3h5r3HUrhsEDTcwowafEA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25623 uniprotkb:P36027 intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320037|imex:IM-14275-558 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) crc64:6F35C8F1562E41CC - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:E5D21555510B6E1C|rigid:9E8z4BNEIyVyrqb1gBoyA6yhCAM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25623 uniprotkb:P37370 intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320048|imex:IM-14275-559 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370 psi-mi:"MI:0469"(intact) crc64:6F35C8F1562E41CC crc64:24C7522D5B1CA1C8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 intact-crc:4190C814B21598AC|rigid:SwqUCCkXA21KLoDx27eXT74aHAg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39719 uniprotkb:P25623 intact:EBI-20703|uniprotkb:Q05165|uniprotkb:D6VPG5|ensemblfungi:YAL053W intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C psi-mi:flc2_yeast(display_long)|uniprotkb:YAL053W(locus name)|uniprotkb:FLC2(gene name)|psi-mi:FLC2(display_short)|uniprotkb:FAD transporter 2(gene name synonym)|uniprotkb:TRP-like ion channel FLC2(gene name synonym) psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320059|imex:IM-14275-560 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009348.2|sgd:S000000049|ensemblfungi:YAL053W(gene)|ensemblfungi:YAL053W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241|go:"GO:0055085"(transmembrane transport)|dip:DIP-6708N|mint:P39719 refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) - crc64:6F35C8F1562E41CC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:NOmMW54DNa0o7vM945DlZgVUy44559292 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 intact-crc:251C1FE11E647FB8|rigid:d5n6X4ksigxUxfuOz+V5ucrko38 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43603 uniprotkb:P25623 intact:EBI-22980|uniprotkb:D6VTQ4|ensemblfungi:YFR024C-A intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C psi-mi:lsb3_yeast(display_long)|uniprotkb:LSB3(gene name)|psi-mi:LSB3(display_short)|uniprotkb:YFR024C(orf name)|uniprotkb:YFR024C-A(locus name) psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320070|imex:IM-14275-561 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002968|refseq:NP_219497.4|dip:DIP-6259N|mint:P43603|ensemblfungi:YFR024C-A(gene)|ensemblfungi:YFR024C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:1OOT|rcsb pdb:1SSH refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:F486C787B5771AAC crc64:6F35C8F1562E41CC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zKMZQRpG4d/at/NecQDyEi/kVKg559292 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 intact-crc:BEA2A2DA734DAC8A|rigid:GeQP5Ni9TSV1Wwg3NQ76Y93tmgI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53278 uniprotkb:P25623 intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name) psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320081|imex:IM-14275-562 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome) refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:D482327C9274C026 crc64:6F35C8F1562E41CC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 intact-crc:D9950805B32BEDBC|rigid:uFVsRKXNyHjCupIA8MRJ+dj+WEU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25623 uniprotkb:P53832 intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C intact:EBI-2055941|uniprotkb:D6W0R1|ensemblfungi:YNL283C psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:wsc2_yeast(display_long)|uniprotkb:YNL283C(locus name)|uniprotkb:N0583(orf name)|uniprotkb:WSC2(gene name)|psi-mi:WSC2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320092|imex:IM-14275-563 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 refseq:NP_014116.1|sgd:S000005227|interpro:IPR002889(Carbohydrate-binding WSC)|mint:P53832|ensemblfungi:YNL283C(gene)|ensemblfungi:YNL283C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip) psi-mi:"MI:0469"(intact) crc64:6F35C8F1562E41CC - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 rogid:5wadvTv6SxcIAb60yfnuGMfa8pY559292 intact-crc:AA79E1EE008B1681|rigid:7+yCk8BlEvGe8WI9IVDKKlmY8uA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25623 uniprotkb:Q04439 intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C intact:EBI-11687|ensemblfungi:YMR109W|uniprotkb:D6VZT2 psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:myo5_yeast(display_long)|uniprotkb:MYO5(gene name)|psi-mi:MYO5(display_short)|uniprotkb:YMR109W(locus name)|uniprotkb:YM9718.08(orf name)|uniprotkb:Class I unconventional myosin MYO5(gene name synonym)|uniprotkb:Type I myosin MYO5(gene name synonym)|uniprotkb:Actin-dependent myosin-I MYO5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320114|imex:IM-14275-565 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 ensemblfungi:YMR109W_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0009651"(response to salt stress)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051286"(cell tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071944"(cell periphery)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035535|ensemblfungi:YMR109W(gene)|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|rcsb pdb:1YP5|rcsb pdb:1ZUY|refseq:NP_013827.1|sgd:S000004715|mint:Q04439|dip:DIP-2222N psi-mi:"MI:0469"(intact) crc64:6F35C8F1562E41CC crc64:DFFB9EC16B61CD29 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 rogid:n/Po/L9Xd7LP+fY39QaqP/s5US4559292 intact-crc:FB493DAC6BAFD2E4|rigid:n4SgYf8OegWsxScko5fF+XUFNLY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02785 uniprotkb:P25623 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320103|imex:IM-14275-564 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) - crc64:6F35C8F1562E41CC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 intact-crc:61084C4B03CD5DC0|rigid:WmoMTadioTay2qerwT8q9zSaIJk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07657 uniprotkb:P25623 intact:EBI-22083|uniprotkb:D6VRD0|ensemblfungi:YDL225W intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C psi-mi:shs1_yeast(display_long)|uniprotkb:YDL225W(locus name)|uniprotkb:Septation protein 7(gene name synonym)|uniprotkb:SHS1(gene name)|psi-mi:SHS1(display_short)|uniprotkb:SEP7(gene name synonym) psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320136|imex:IM-14275-567 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010056.1|sgd:S000002384|dip:DIP-5596N|ensemblfungi:YDL225W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010458"(exit from mitosis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043332"(mating projection tip)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061163"(endoplasmic reticulum polarization)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097271"(protein localization to bud neck)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|ensemblfungi:YDL225W(gene)|mint:Q07657 refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:BDA2631061A278F9 crc64:6F35C8F1562E41CC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4A/dWGsbB5nAWr1kP+zTlT9B3z4559292 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 intact-crc:4EB584E191B9FDFA|rigid:xa5h7ghz1twZQsaHHu6VkInlo3U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25623 uniprotkb:Q05785 intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C intact:EBI-35928|uniprotkb:D6VYK7|ensemblfungi:YLR206W psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:ent2_yeast(display_long)|uniprotkb:YLR206W(locus name)|uniprotkb:ENT2(gene name)|psi-mi:ENT2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320125|imex:IM-14275-566 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 refseq:NP_013307.1|sgd:S000004196|mint:Q05785|dip:DIP-2698N|ensemblfungi:YLR206W(gene)|ensemblfungi:YLR206W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043332"(mating projection tip)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:4GZC|rcsb pdb:4GZD|rcsb pdb:5ON7|rcsb pdb:6ENR|reactome:R-SCE-8856825 psi-mi:"MI:0469"(intact) crc64:6F35C8F1562E41CC crc64:CEC1B2D04C0F7D86 figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 rogid:o7k85Z9SbqAjFGEc+28iwiR4CxQ559292 intact-crc:DF38C9B52CFCAF39|rigid:Q2Qyx/2ck8kh+t+J3KUh2ctTy/0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08967 uniprotkb:P25623 intact:EBI-36673|uniprotkb:D6W3E9|ensemblfungi:YPL221W intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C psi-mi:flc1_yeast(display_long)|uniprotkb:FAD transporter 1(gene name synonym)|uniprotkb:FLC1(gene name)|psi-mi:FLC1(display_short)|uniprotkb:TRP-like ion channel protein FLC1(gene name synonym)|uniprotkb:Heme utilization factor 1(gene name synonym)|uniprotkb:Bypass of PAM1 protein 1(gene name synonym)|uniprotkb:HUF1(gene name synonym)|uniprotkb:YPL221W(locus name)|uniprotkb:BOP1(gene name synonym) psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320147|imex:IM-14275-568 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015103.1|sgd:S000006142|mint:Q08967|dip:DIP-3965N|ensemblfungi:YPL221W(gene)|ensemblfungi:YPL221W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055085"(transmembrane transport)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241 refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) - crc64:6F35C8F1562E41CC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:r6CcZGEjxHUk2w0iBUBvnAPaFd4559292 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 intact-crc:D8AF1078747CF4A1|rigid:OPrPNtYjxPJbTg2KFhsiYScDj1I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12446 uniprotkb:P25623 intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name) psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320169|imex:IM-14275-570 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446 refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:4488355563AA2645 crc64:6F35C8F1562E41CC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 intact-crc:5E5C22CE86BAA98C|rigid:4BC2HEW2/YoWXNr/kSJlUxwZmEE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12335 uniprotkb:P25623 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320158|imex:IM-14275-569 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:1056E7A1F3E82288 crc64:6F35C8F1562E41CC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 intact-crc:64BF8EBA2BAD7F27|rigid:jDUmZDWEbM8gHD1cInSCPCJYZPQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25637 uniprotkb:P33892 intact:EBI-21951|uniprotkb:D6VR64|ensemblfungi:YCR059C intact:EBI-7442|uniprotkb:D6VTV8|ensemblfungi:YGL195W psi-mi:yih1_yeast(display_long)|uniprotkb:YCR59C(orf name)|uniprotkb:YCR059C(locus name)|uniprotkb:YIH1(gene name)|psi-mi:YIH1(display_short) psi-mi:gcn1_yeast(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:General control non-derepressible protein 1(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym)|uniprotkb:G1318(orf name)|uniprotkb:YGL195W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320180|imex:IM-14275-571 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009985.1|sgd:S000000655|mint:P25637|dip:DIP-1846N|ensemblfungi:YCR059C(gene)|ensemblfungi:YCR059C_mRNA(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0043022"(ribosome binding)|go:"GO:0140469"(GCN2-mediated signaling)|go:"GO:1905538"(polysome binding)|interpro:IPR001498(Protein of unknown function UPF0029, N-terminal)|interpro:IPR006575(RWD)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR020568|interpro:IPR020569|interpro:IPR023582|interpro:IPR036956|rcsb pdb:6BQI|rcsb pdb:6U1L|rcsb pdb:6U1O sgd:S000003163|refseq:NP_011320.3|mint:P33892|dip:DIP-2344N|ensemblfungi:YGL195W(gene)|ensemblfungi:YGL195W_mRNA(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071264"(positive regulation of translational initiation in response to starvation)|go:"GO:0072755"(cellular response to benomyl)|go:"GO:0140469"(GCN2-mediated signaling)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1990451"(cellular stress response to acidic pH)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR022716|interpro:IPR033173|interpro:IPR034085 psi-mi:"MI:0469"(intact) - crc64:980FDD03753E9D1C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aAbGir3o4M0LUpwOv6YBC25KpQQ559292 rogid:WPYtEB/xjy4g2cJFwhe+2teVYVk559292 intact-crc:6D3BD8544D227E8B|rigid:VPio0DWs5ZzZzbsUjYDtokrgbi8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25655 uniprotkb:P06102 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-12165|uniprotkb:D6VVP4|uniprotkb:Q6B233|ensemblfungi:YIL038C psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:not3_yeast(display_long)|uniprotkb:NOT3(gene name)|psi-mi:NOT3(display_short)|uniprotkb:YIL038C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320191|imex:IM-14275-572 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR038635|interpro:IPR040168|ensemblfungi:YIL038C(gene)|ensemblfungi:YIL038C_mRNA(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|refseq:NP_012226.3|sgd:S000001300|dip:DIP-2256N|mint:P06102 psi-mi:"MI:0469"(intact) crc64:5B2AE15BCF95E009 crc64:69B76694FCC6846F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:EfakZPDNU3FZeI5+rnu7YV1UsCg559292 intact-crc:6100B04E2E1BC201|rigid:+uPy6SQC4gfXNSjXJ8/+n8sBxFw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34761 uniprotkb:P25655 intact:EBI-20537|uniprotkb:D6W0Z0|ensemblfungi:YNL197C intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W psi-mi:whi3_yeast(display_long)|uniprotkb:WHI3(gene name)|psi-mi:WHI3(display_short)|uniprotkb:N1382(orf name)|uniprotkb:YNL197C(locus name) psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320213|imex:IM-14275-574 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014202.1|sgd:S000005141|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|ensemblfungi:YNL197C(gene)|ensemblfungi:YNL197C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0032106"(positive regulation of response to extracellular stimulus)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0061013"(regulation of mRNA catabolic process)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071554"(cell wall organization or biogenesis)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P34761 ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 psi-mi:"MI:0469"(intact) - crc64:5B2AE15BCF95E009 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Xpn0uJiaylcupy9qYDLa0V++z6A559292 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 intact-crc:48D5F726C666F25C|rigid:sKlPBiYtA1Xf3MssrBAXMItBJE4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25655 uniprotkb:P25655 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320202|imex:IM-14275-573 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 psi-mi:"MI:0469"(intact) crc64:5B2AE15BCF95E009 crc64:5B2AE15BCF95E009 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 intact-crc:A4D0A114D64D9F1A|rigid:BETuS3P1nz17nJgqgDOBzizCj3c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25655 uniprotkb:P34909 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320224|imex:IM-14275-575 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 psi-mi:"MI:0469"(intact) crc64:5B2AE15BCF95E009 crc64:8847084BD9BF48B7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 intact-crc:1BB104735EFDCAA5|rigid:IiuM2qWmT0VyMAABn9jmgrhKARk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25655 uniprotkb:P39008 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320246|imex:IM-14275-577 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N psi-mi:"MI:0469"(intact) crc64:5B2AE15BCF95E009 crc64:F3CAF97106A65933 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 intact-crc:BD6B3128BC60113A|rigid:4HSUcQXMUkpB6qlyKvwZlmBucnc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25655 uniprotkb:P35732 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320235|imex:IM-14275-576 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 psi-mi:"MI:0469"(intact) crc64:5B2AE15BCF95E009 crc64:05734E2D0B7389AC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 intact-crc:C380E634AFC313A3|rigid:+/W1Ec/CmGbDDFL35v92cZt5UhQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25655 uniprotkb:P53829 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320268|imex:IM-14275-579 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 psi-mi:"MI:0469"(intact) crc64:5B2AE15BCF95E009 crc64:F3DBABE6AD3C7F3C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 intact-crc:9C021CA5F737CFC0|rigid:isaYayYhAW9IbzmUvfvFVgG+ub0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40070 uniprotkb:P25655 intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320257|imex:IM-14275-578 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 psi-mi:"MI:0469"(intact) crc64:69CAC1F01D5BFA98 crc64:5B2AE15BCF95E009 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 intact-crc:51F6A2EC8E4608FE|rigid:9nAk2dUW3l/LQEXD7QqPjMuBVIs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53935 uniprotkb:P25655 intact:EBI-28788|uniprotkb:Q45TZ3|uniprotkb:D6W189|ensemblfungi:YNL091W intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W psi-mi:nst1_yeast(display_long)|uniprotkb:YNL091W(locus name)|uniprotkb:N2231(orf name)|uniprotkb:NST1(gene name)|psi-mi:NST1(display_short)|uniprotkb:Negatively-affecting salt tolerance protein 1(gene name synonym) psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320279|imex:IM-14275-580 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014308.1|sgd:S000005035|dip:DIP-872N|mint:P53935|ensemblfungi:YNL091W(gene)|ensemblfungi:YNL091W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009651"(response to salt stress)|interpro:IPR025279 ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 psi-mi:"MI:0469"(intact) - crc64:5B2AE15BCF95E009 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WOSVMqWhtYPlZyt+vfdkpJAHHBg559292 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 intact-crc:D1208FBE6247959E|rigid:hTh+Drc+i9lJkdkpgolADzp8eEU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06406 uniprotkb:P25655 intact:EBI-196|uniprotkb:D6VT10|ensemblfungi:YDR378C intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W psi-mi:lsm6_yeast(display_long)|uniprotkb:LSM6(gene name)|psi-mi:LSM6(display_short)|uniprotkb:D9481.18(orf name)|uniprotkb:YDR378C(locus name) psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320301|imex:IM-14275-582 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010666.2|sgd:S000002786|mint:Q06406|dip:DIP-1418N|ensemblfungi:YDR378C(gene)|ensemblfungi:YDR378C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0008033"(tRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 psi-mi:"MI:0469"(intact) crc64:74FE40A4509CEF33 crc64:5B2AE15BCF95E009 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:JQtrhOkngO6APIPCFMRnKogB96c559292 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 intact-crc:0E173E06359FD601|rigid:T86WmG1Vi1YJmZw2oHbeNkw/xAc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25655 uniprotkb:P57743 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-10227|uniprotkb:Q05176|uniprotkb:Q06759|uniprotkb:D6VZ73|ensemblfungi:YLR438C-A psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:lsm3_yeast(display_long)|uniprotkb:LSM3(gene name)|psi-mi:LSM3(display_short)|uniprotkb:SMX4(gene name synonym)|uniprotkb:USS2(gene name synonym)|uniprotkb:YLR438C-A(locus name)|uniprotkb:SmX4 protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320290|imex:IM-14275-581 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 sgd:S000006434|ensemblfungi:YLR438C-A(gene)|ensemblfungi:YLR438C-A_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034105|interpro:IPR040002|rcsb pdb:3BW1|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:4N0A|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039|rcsb pdb:4M75|refseq:NP_013543.3|dip:DIP-2587N|mint:P57743 psi-mi:"MI:0469"(intact) crc64:5B2AE15BCF95E009 crc64:787084EF6A5945B7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:nYl7At1SnlSwN+nWr1F1xm0tdDE559292 intact-crc:91B8E37BCB4EF6F3|rigid:6zGc6+N/R+UbEn0zxyS3xTTTx2Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25655 uniprotkb:Q12514 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-12184|uniprotkb:D6W476|ensemblfungi:YPR072W psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:not5_yeast(display_long)|uniprotkb:NOT5(gene name)|psi-mi:NOT5(display_short)|uniprotkb:YP9499.27(orf name)|uniprotkb:YPR072W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320312|imex:IM-14275-583 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 ensemblfungi:YPR072W(gene)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|rcsb pdb:6TB3|ensemblfungi:YPR072W_mRNA(transcript)|refseq:NP_015397.1|sgd:S000006276|dip:DIP-2257N|mint:Q12514 psi-mi:"MI:0469"(intact) crc64:5B2AE15BCF95E009 crc64:073137119B3E92BC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:+XON8Ps4xCFhw058U9d2voUy2dc559292 intact-crc:10793607E8E128B3|rigid:TBHDPUbFFXtQAOmtDJULM2bck1I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:P19807 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320323|imex:IM-14275-584 author score:99.32 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) crc64:8B7F009521F72C15 - figure legend:tables S3 and S4|author-confidence:99.32|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:4EF5F4CB2FBC9CEA|rigid:xQfSbc+Zj57Ia3BEzgFURoyv3PA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:P26570 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320334|imex:IM-14275-585 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N psi-mi:"MI:0469"(intact) crc64:8B7F009521F72C15 crc64:8B7F009521F72C15 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 intact-crc:08F07522BFBC94E4|rigid:XPqOhD1g2KNXgCNytyn/tgUSAAo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:P36024 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320356|imex:IM-14275-587 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024 psi-mi:"MI:0469"(intact) crc64:8B7F009521F72C15 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292 intact-crc:A1CE9A91EED87193|rigid:u4cf20lMa8VKz3P+Y3/CNTQFeoo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P26570 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320345|imex:IM-14275-586 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N psi-mi:"MI:0469"(intact) - crc64:8B7F009521F72C15 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 intact-crc:935EF7A317E6483A|rigid:hWMdGUkW5n/jUv0hrW7IV9apqsE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:P36027 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320367|imex:IM-14275-588 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) crc64:8B7F009521F72C15 - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:B108049B80C4936E|rigid:XN2JEuua6RBxpEVGiktw9HIX450 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:P36076 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320378|imex:IM-14275-589 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783 psi-mi:"MI:0469"(intact) crc64:8B7F009521F72C15 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:Li7vZOassm4PC5fW111/j5ivgEc559292 intact-crc:2A9DD1FA1B82E81D|rigid:dgCALvIJ7I7h3RD+Hxf37fYBTl8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P26570 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320389|imex:IM-14275-590 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N psi-mi:"MI:0469"(intact) - crc64:8B7F009521F72C15 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 intact-crc:51DD0AAE5A624DFD|rigid:VMhvsWB2f3dYYRjfPY2kyoGn09o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:Q02785 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320400|imex:IM-14275-591 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) crc64:8B7F009521F72C15 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:35DFDEE5D202A0B2|rigid:JmQC+0oF2u2dM86upjzEl8gh6P8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08438 uniprotkb:P26570 intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name) psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320411|imex:IM-14275-592 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551 ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N psi-mi:"MI:0469"(intact) crc64:A97623473CB6F605 crc64:8B7F009521F72C15 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 intact-crc:73206BA7B3E1D87A|rigid:3N/QhSuFkXchCOLbvVZERn+2OF8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:Q08967 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-36673|uniprotkb:D6W3E9|ensemblfungi:YPL221W psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:flc1_yeast(display_long)|uniprotkb:FAD transporter 1(gene name synonym)|uniprotkb:FLC1(gene name)|psi-mi:FLC1(display_short)|uniprotkb:TRP-like ion channel protein FLC1(gene name synonym)|uniprotkb:Heme utilization factor 1(gene name synonym)|uniprotkb:Bypass of PAM1 protein 1(gene name synonym)|uniprotkb:HUF1(gene name synonym)|uniprotkb:YPL221W(locus name)|uniprotkb:BOP1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320422|imex:IM-14275-593 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N refseq:NP_015103.1|sgd:S000006142|mint:Q08967|dip:DIP-3965N|ensemblfungi:YPL221W(gene)|ensemblfungi:YPL221W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055085"(transmembrane transport)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241 psi-mi:"MI:0469"(intact) crc64:8B7F009521F72C15 - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:r6CcZGEjxHUk2w0iBUBvnAPaFd4559292 intact-crc:8C788776AD9309D3|rigid:Xk2asW6OwOBNqQVo8ksgbiT9TZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:Q12256 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320433|imex:IM-14275-594 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:8B7F009521F72C15 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 intact-crc:C833C8FD4B847C99|rigid:pn1GEDDz0YbTaNZWt3kI6XDhLg0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99271 uniprotkb:P26570 intact:EBI-11808|ensemblfungi:YLR138W|uniprotkb:D6VYD3 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 psi-mi:nah1_yeast(display_long)|uniprotkb:NHA1(gene name)|psi-mi:NHA1(display_short)|uniprotkb:L3149(orf name)|uniprotkb:L9606.4(orf name)|uniprotkb:YLR138W(locus name) psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320444|imex:IM-14275-595 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0045121"(membrane raft)|go:"GO:0097623"(potassium ion export across plasma membrane)|interpro:IPR004712(Fungal Na+/H+ antiporter)|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR013928(Alkali metal cation/H+ antiporter Nha1, C-terminal)|interpro:IPR032516|interpro:IPR038770|rcsb pdb:6QK8|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|ensemblfungi:YLR138W(gene)|ensemblfungi:YLR138W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0015079"(potassium ion transmembrane transporter activity)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0015491"("cation:cation antiporter activity")|go:"GO:0016021"(integral component of membrane)|refseq:NP_013239.1|sgd:S000004128|dip:DIP-6364N|mint:Q99271 ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N psi-mi:"MI:0469"(intact) crc64:AD0B86D483DCDD89 crc64:8B7F009521F72C15 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:88+AXuO37BRzdlHWPDvWAESQM+M559292 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 intact-crc:56E5088E008E0DFB|rigid:4fXygKxbeHs+njC/Up0/n+YKjDU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36143 uniprotkb:P27472 intact:EBI-2064417|uniprotkb:D6VXB9|ensemblfungi:YKR058W intact:EBI-8036|uniprotkb:D6VYQ5|ensemblfungi:YLR258W psi-mi:glg1_yeast(display_long)|uniprotkb:GLG1(gene name)|psi-mi:GLG1(display_short)|uniprotkb:Glycogenin glucosyltransferase 1(gene name synonym)|uniprotkb:Glycogen synthesis initiator protein 1(gene name synonym)|uniprotkb:YKR058W(locus name) psi-mi:gys2_yeast(display_long)|uniprotkb:L8479.8(orf name)|uniprotkb:YLR258W(locus name)|uniprotkb:GSY2(gene name)|psi-mi:GSY2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320466|imex:IM-14275-597 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012984.2|sgd:S000001766|interpro:IPR002495(Glycosyl transferase, family 8)|interpro:IPR029044|mint:P36143|ensemblfungi:YKR058W(gene)|ensemblfungi:YKR058W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0008466"(glycogenin glucosyltransferase activity)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0102751"("UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity")|reactome:R-SCE-3322077|reactome:R-SCE-70221 refseq:NP_013359.1|sgd:S000004248|mint:P27472|dip:DIP-1255N|ensemblfungi:YLR258W(gene)|ensemblfungi:YLR258W_mRNA(transcript)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR008631(Glycogen synthase)|rcsb pdb:3NAZ|rcsb pdb:3NB0|rcsb pdb:3NCH|rcsb pdb:3O3C|rcsb pdb:3RSZ|rcsb pdb:3RT1|rcsb pdb:4KQ2|rcsb pdb:4KQM|rcsb pdb:5SUK|rcsb pdb:5SUL|rcsb pdb:5UW0|rcsb pdb:5UW1|rcsb pdb:5UW4|rcsb pdb:5UX7|rcsb pdb:5VNC|rcsb pdb:6U77|reactome:R-SCE-3322077 psi-mi:"MI:0469"(intact) - crc64:4670D8328CEDB0D2 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XK7v4e4eSk6bi7JtQcL1HOr9M78559292 rogid:K8l8dzJOtoIWZHpDN8Bq31o6ahA559292 intact-crc:7660EE58B2187F4C|rigid:eL6QGMijOmiVY5OgHYPFtADSUXE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27472 uniprotkb:P27472 intact:EBI-8036|uniprotkb:D6VYQ5|ensemblfungi:YLR258W intact:EBI-8036|uniprotkb:D6VYQ5|ensemblfungi:YLR258W psi-mi:gys2_yeast(display_long)|uniprotkb:L8479.8(orf name)|uniprotkb:YLR258W(locus name)|uniprotkb:GSY2(gene name)|psi-mi:GSY2(display_short) psi-mi:gys2_yeast(display_long)|uniprotkb:L8479.8(orf name)|uniprotkb:YLR258W(locus name)|uniprotkb:GSY2(gene name)|psi-mi:GSY2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320455|imex:IM-14275-596 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013359.1|sgd:S000004248|mint:P27472|dip:DIP-1255N|ensemblfungi:YLR258W(gene)|ensemblfungi:YLR258W_mRNA(transcript)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR008631(Glycogen synthase)|rcsb pdb:3NAZ|rcsb pdb:3NB0|rcsb pdb:3NCH|rcsb pdb:3O3C|rcsb pdb:3RSZ|rcsb pdb:3RT1|rcsb pdb:4KQ2|rcsb pdb:4KQM|rcsb pdb:5SUK|rcsb pdb:5SUL|rcsb pdb:5UW0|rcsb pdb:5UW1|rcsb pdb:5UW4|rcsb pdb:5UX7|rcsb pdb:5VNC|rcsb pdb:6U77|reactome:R-SCE-3322077 refseq:NP_013359.1|sgd:S000004248|mint:P27472|dip:DIP-1255N|ensemblfungi:YLR258W(gene)|ensemblfungi:YLR258W_mRNA(transcript)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR008631(Glycogen synthase)|rcsb pdb:3NAZ|rcsb pdb:3NB0|rcsb pdb:3NCH|rcsb pdb:3O3C|rcsb pdb:3RSZ|rcsb pdb:3RT1|rcsb pdb:4KQ2|rcsb pdb:4KQM|rcsb pdb:5SUK|rcsb pdb:5SUL|rcsb pdb:5UW0|rcsb pdb:5UW1|rcsb pdb:5UW4|rcsb pdb:5UX7|rcsb pdb:5VNC|rcsb pdb:6U77|reactome:R-SCE-3322077 psi-mi:"MI:0469"(intact) crc64:4670D8328CEDB0D2 crc64:4670D8328CEDB0D2 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K8l8dzJOtoIWZHpDN8Bq31o6ahA559292 rogid:K8l8dzJOtoIWZHpDN8Bq31o6ahA559292 intact-crc:E67DE3E03C8EA2DC|rigid:a8PFjDEfRyaKhW66BasafN4WDec false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27472 uniprotkb:P38009 intact:EBI-8036|uniprotkb:D6VYQ5|ensemblfungi:YLR258W intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 psi-mi:gys2_yeast(display_long)|uniprotkb:L8479.8(orf name)|uniprotkb:YLR258W(locus name)|uniprotkb:GSY2(gene name)|psi-mi:GSY2(display_short) psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320477|imex:IM-14275-598 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013359.1|sgd:S000004248|mint:P27472|dip:DIP-1255N|ensemblfungi:YLR258W(gene)|ensemblfungi:YLR258W_mRNA(transcript)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR008631(Glycogen synthase)|rcsb pdb:3NAZ|rcsb pdb:3NB0|rcsb pdb:3NCH|rcsb pdb:3O3C|rcsb pdb:3RSZ|rcsb pdb:3RT1|rcsb pdb:4KQ2|rcsb pdb:4KQM|rcsb pdb:5SUK|rcsb pdb:5SUL|rcsb pdb:5UW0|rcsb pdb:5UW1|rcsb pdb:5UW4|rcsb pdb:5UX7|rcsb pdb:5VNC|rcsb pdb:6U77|reactome:R-SCE-3322077 refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N psi-mi:"MI:0469"(intact) crc64:4670D8328CEDB0D2 crc64:8ABA71761B512242 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K8l8dzJOtoIWZHpDN8Bq31o6ahA559292 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 intact-crc:D28DC78C1B80203C|rigid:5etmUgObhElQnUm+8d/pZoWmjVI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27472 uniprotkb:Q06625 intact:EBI-8036|uniprotkb:D6VYQ5|ensemblfungi:YLR258W intact:EBI-37861|uniprotkb:O93808|uniprotkb:D6W4I4|ensemblfungi:YPR184W psi-mi:gys2_yeast(display_long)|uniprotkb:L8479.8(orf name)|uniprotkb:YLR258W(locus name)|uniprotkb:GSY2(gene name)|psi-mi:GSY2(display_short) psi-mi:gde_yeast(display_long)|uniprotkb:GDB1(gene name)|psi-mi:GDB1(display_short)|uniprotkb:Glycogen debrancher(gene name synonym)|uniprotkb:YPR184W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320488|imex:IM-14275-599 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013359.1|sgd:S000004248|mint:P27472|dip:DIP-1255N|ensemblfungi:YLR258W(gene)|ensemblfungi:YLR258W_mRNA(transcript)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR008631(Glycogen synthase)|rcsb pdb:3NAZ|rcsb pdb:3NB0|rcsb pdb:3NCH|rcsb pdb:3O3C|rcsb pdb:3RSZ|rcsb pdb:3RT1|rcsb pdb:4KQ2|rcsb pdb:4KQM|rcsb pdb:5SUK|rcsb pdb:5SUL|rcsb pdb:5UW0|rcsb pdb:5UW1|rcsb pdb:5UW4|rcsb pdb:5UX7|rcsb pdb:5VNC|rcsb pdb:6U77|reactome:R-SCE-3322077 refseq:NP_015510.1|sgd:S000006388|dip:DIP-2578N|mint:Q06625|ensemblfungi:YPR184W(gene)|ensemblfungi:YPR184W_mRNA(transcript)|go:"GO:0004134"(4-alpha-glucanotransferase activity)|go:"GO:0004135"(amylo-alpha-1,6-glucosidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0102500"(beta-maltose 4-alpha-glucanotransferase activity)|interpro:IPR006421(Glycogen debranching enzyme)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR010401(Amylo-alpha-1,6-glucosidase)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR029436|interpro:IPR032788|interpro:IPR032790|interpro:IPR032792|reactome:R-SCE-6798695|reactome:R-SCE-70221 psi-mi:"MI:0469"(intact) crc64:4670D8328CEDB0D2 crc64:167270B2EE15EDF9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K8l8dzJOtoIWZHpDN8Bq31o6ahA559292 rogid:PyGiuO1EwYCEOX9FCvZwBaxSAJ4559292 intact-crc:6D20F0053A9BDEDF|rigid:g+62jTlcLAK4hS4fq1keTfuRhUM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28007 uniprotkb:P20434 intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C intact:EBI-15781|uniprotkb:Q02121|ensemblfungi:YBR154C|uniprotkb:D6VQE9 psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:rpab1_yeast(display_long)|uniprotkb:RPB5(gene name)|psi-mi:RPB5(display_short)|uniprotkb:YBR154C(locus name)|uniprotkb:YBR1204(orf name)|uniprotkb:RPA7(gene name synonym)|uniprotkb:RPC9(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide(gene name synonym)|uniprotkb:ABC27(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320510|imex:IM-14275-601 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|rcsb pdb:1WCM|rcsb pdb:1Y1V|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|rcsb pdb:2B63|rcsb pdb:2B8K|interpro:IPR020608|interpro:IPR020609|rcsb pdb:2E2H|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:1DZF|rcsb pdb:1I3Q|rcsb pdb:2E2I|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:5M5Y|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6H67|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:2E2J|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|ensemblfungi:YBR154C(gene)|ensemblfungi:YBR154C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4V1M|rcsb pdb:2JA5|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2JA6|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:2JA7|rcsb pdb:3GTG|rcsb pdb:2JA8|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:2NVQ|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4YM7|rcsb pdb:5C3E|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5G5L|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6H68|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|rcsb pdb:6UQ2|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-77075|reactome:R-SCE-9018519|refseq:NP_009712.1|sgd:S000000358|dip:DIP-71N|mint:P20434 psi-mi:"MI:0469"(intact) crc64:C197FE85644DD0F8 crc64:2A15F7114D69D829 figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 rogid:j/jAJ2fXWf4ebK1aWTWrKERGUpM559292 intact-crc:F487A3DC3C0F8016|rigid:lLGTI15rdoI4mDdJ5PgX3yDJWhw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10964 uniprotkb:P28007 intact:EBI-15730|uniprotkb:Q99330|uniprotkb:D6W336|ensemblfungi:YOR341W intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C psi-mi:rpa1_yeast(display_long)|uniprotkb:RPA190(gene name)|psi-mi:RPA190(display_short)|uniprotkb:RPA1(gene name synonym)|uniprotkb:RRN1(gene name synonym)|uniprotkb:YOR341W(locus name)|uniprotkb:O6276(orf name)|uniprotkb:DNA-directed RNA polymerase I 190 kDa polypeptide(gene name synonym)|uniprotkb:DNA-directed RNA polymerase I largest subunit(gene name synonym) psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320499|imex:IM-14275-600 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005868|refseq:NP_014986.3|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR015699(DNA-directed RNA pol I, largest subunit)|interpro:IPR038120|interpro:IPR042102|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|ensemblfungi:YOR341W(gene)|ensemblfungi:YOR341W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0008270"(zinc ion binding)|dip:DIP-999N|mint:P10964 refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI psi-mi:"MI:0469"(intact) crc64:DF65A7AA459D5E6D crc64:C197FE85644DD0F8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:krXuLY5fTE34McW4bnuPqns5Oy4559292 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 intact-crc:048A31DD8154BCB1|rigid:a2KO8Z2OtUFLd4+4K2W4YMW9d4k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28007 uniprotkb:P20447 intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C intact:EBI-5608|uniprotkb:D6VU66|ensemblfungi:YGL078C psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:dbp3_yeast(display_long)|uniprotkb:YGL078C(locus name)|uniprotkb:DBP3(gene name)|psi-mi:DBP3(display_short)|uniprotkb:DEAD box protein 3(gene name synonym)|uniprotkb:Helicase CA3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320521|imex:IM-14275-602 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI sgd:S000003046|refseq:NP_011437.3|dip:DIP-2668N|mint:P20447|ensemblfungi:YGL078C(gene)|ensemblfungi:YGL078C_mRNA(transcript)|go:"GO:0000464"("endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417 psi-mi:"MI:0469"(intact) crc64:C197FE85644DD0F8 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 rogid:9ltHUfhcU8nfN3bxsmkabo8A2L4559292 intact-crc:4BA7DFE1EC974419|rigid:Vk6e9Y2M2eyxj6A0tKzVpiIxo0s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28007 uniprotkb:P24783 intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320543|imex:IM-14275-604 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) crc64:C197FE85644DD0F8 crc64:30FE3D4C7E653120 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 intact-crc:3DE1C1772E62DACD|rigid:FIG8bMWAdHKq2HGhoSAeYC1nNkg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28007 uniprotkb:P21304 intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C intact:EBI-14328|uniprotkb:D6VYJ9|ensemblfungi:YLR196W psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:pwp1_yeast(display_long)|uniprotkb:L8167.10(orf name)|uniprotkb:YLR196W(locus name)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320532|imex:IM-14275-603 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI refseq:NP_013297.1|sgd:S000004186|ensemblfungi:YLR196W(gene)|ensemblfungi:YLR196W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR044285|mint:P21304|dip:DIP-4203N psi-mi:"MI:0469"(intact) crc64:C197FE85644DD0F8 crc64:FC0189B289494AB5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 rogid:Q1nPXtlkpIw8JosaiYX0PSVNaSw559292 intact-crc:B051178D39F73C6F|rigid:IJsvWBRxwrYy5olqAbqAKCiBznk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27476 uniprotkb:P28007 intact:EBI-12274|ensemblfungi:YGR159C|uniprotkb:D6VUT9 intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C psi-mi:nsr1_yeast(display_long)|uniprotkb:NSR1(gene name)|psi-mi:NSR1(display_short)|uniprotkb:YGR159C(locus name)|uniprotkb:G7001(orf name)|uniprotkb:p67(gene name synonym) psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320554|imex:IM-14275-605 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR159C(gene)|ensemblfungi:YGR159C_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034276|interpro:IPR035979|interpro:IPR034272|refseq:NP_011675.1|sgd:S000003391|mint:P27476|dip:DIP-5537N refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI psi-mi:"MI:0469"(intact) crc64:90DEEE7BBC20BC0C crc64:C197FE85644DD0F8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:q0/AgJC55iTpn/5kCsxal2kQ7Ls559292 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 intact-crc:AAFC53C25C2949C1|rigid:HhHL29SkfvrSR36PArQm5a5CoOw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28007 uniprotkb:P28007 intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320565|imex:IM-14275-606 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI psi-mi:"MI:0469"(intact) crc64:C197FE85644DD0F8 crc64:C197FE85644DD0F8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 intact-crc:23A8DAD1E01D46FB|rigid:/6d/bufUURPInbyH+c31DMijDu8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28007 uniprotkb:P32583 intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C intact:EBI-17992|uniprotkb:D6VXF2|ensemblfungi:YKR092C psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:srp40_yeast(display_long)|uniprotkb:YKR412A(orf name)|uniprotkb:YKR092C(locus name)|uniprotkb:SRP40(gene name)|psi-mi:SRP40(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320587|imex:IM-14275-608 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI sgd:S000001800|ensemblfungi:YKR092C(gene)|ensemblfungi:YKR092C_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006913"(nucleocytoplasmic transport)|interpro:IPR007718(SRP40, C-terminal)|refseq:NP_013018.3|dip:DIP-2115N|mint:P32583 psi-mi:"MI:0469"(intact) crc64:C197FE85644DD0F8 crc64:8EA007695AF4BA1D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 rogid:bk2gXF1o2Rj+ML2zHj1N52chwMc559292 intact-crc:06CE885E84AB593D|rigid:0ozxLhofoapjQl9GGuhnoKWA3CM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28007 uniprotkb:P32495 intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C intact:EBI-12014|ensemblfungi:YDL208W|uniprotkb:D6VRE6 psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:nhp2_yeast(display_long)|uniprotkb:NHP2(gene name)|psi-mi:NHP2(display_short)|uniprotkb:YDL208W(locus name)|uniprotkb:D1045(orf name)|uniprotkb:H/ACA snoRNP protein NHP2(gene name synonym)|uniprotkb:High mobility group-like nuclear protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320576|imex:IM-14275-607 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI ensemblfungi:YDL208W(gene)|ensemblfungi:YDL208W_mRNA(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000493"(box H/ACA snoRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|rcsb pdb:2LBW|rcsb pdb:2LBX|refseq:NP_010073.2|sgd:S000002367|mint:P32495|dip:DIP-5134N psi-mi:"MI:0469"(intact) crc64:C197FE85644DD0F8 crc64:008188132B494E5D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 rogid:p5AQTuMF3Vvdu6HWSTYjdjjE1Vs559292 intact-crc:2956543875914D6D|rigid:iOhYcyj8og1/K0mZjYMKGMS4xos false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28007 uniprotkb:P38801 intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C intact:EBI-1909|uniprotkb:D3DL32|ensemblfungi:YHR081W psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:lrp1_yeast(display_long)|uniprotkb:LRP1(gene name)|psi-mi:LRP1(display_short)|uniprotkb:Like an rRNA processing protein 1(gene name synonym)|uniprotkb:rRNA processing protein 47(gene name synonym)|uniprotkb:RRP47(gene name synonym)|uniprotkb:YC1D(gene name synonym)|uniprotkb:Yeast C1D domain-containing protein(gene name synonym)|uniprotkb:YHR081W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320598|imex:IM-14275-609 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI refseq:NP_011949.1|sgd:S000001123|dip:DIP-4359N|mint:P38801|ensemblfungi:YHR081W(gene)|ensemblfungi:YHR081W_mRNA(transcript)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071033"|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1901917"(regulation of exoribonuclease activity)|interpro:IPR007146(Small-subunit processome, Utp3)|interpro:IPR011082(Exosome-associated factor Rrp47/DNA strand repair C1D)|rcsb pdb:4WFC|rcsb pdb:4WFD|rcsb pdb:5C0W|rcsb pdb:6FSZ|rcsb pdb:6FT6|rcsb pdb:6LQS|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:C197FE85644DD0F8 crc64:27D00668C296CC9A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 rogid:cQaT2zPsTCZHkLjuYBNF012Ym38559292 intact-crc:A95BA29C3AACA785|rigid:MFBwTvvluoTKXuvlk7ibqfWct6s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43586 uniprotkb:P28007 intact:EBI-22906|uniprotkb:D6VTN1|ensemblfungi:YFR001W intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C psi-mi:loc1_yeast(display_long)|uniprotkb:YFR001W(locus name)|uniprotkb:LOC1(gene name)|psi-mi:LOC1(display_short)|uniprotkb:Localization of ASH1 mRNA protein 1(gene name synonym) psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320620|imex:IM-14275-611 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116656.1|sgd:S000001897|dip:DIP-6615N|mint:P43586|ensemblfungi:YFR001W(gene)|ensemblfungi:YFR001W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051028"(mRNA transport)|go:"GO:0101031"(chaperone complex)|interpro:IPR037650|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)") refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI psi-mi:"MI:0469"(intact) crc64:69970294E9C980F9 crc64:C197FE85644DD0F8 figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9z0K05pOV8o7bqozFWieGjfs/FM559292 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 intact-crc:3DA2C209101A69ED|rigid:em+kMdjWKDkQgRUr9ZvctPLvHoI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28007 uniprotkb:P39744 intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C intact:EBI-29259|uniprotkb:Q08625|uniprotkb:D6W2R2|ensemblfungi:YOR206W psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:noc2_yeast(display_long)|uniprotkb:YOX001(orf name)|uniprotkb:YOR206W(locus name)|uniprotkb:NOC2(gene name)|psi-mi:NOC2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320609|imex:IM-14275-610 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI refseq:NP_014849.3|sgd:S000005732|dip:DIP-4559N|mint:P39744|ensemblfungi:YOR206W(gene)|ensemblfungi:YOR206W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR005343(Protein of unknown function UPF0120) psi-mi:"MI:0469"(intact) crc64:C197FE85644DD0F8 crc64:48C3B9AE076B9B8F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 rogid:d5I8KJOSG63bZ/Pt+XvKdy/SWws559292 intact-crc:24FB53B6C1D6A1B1|rigid:9eTLkjWhWU46wqmWlkDEzpT81Ik false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46669 uniprotkb:P28007 intact:EBI-15745|uniprotkb:Q99187|uniprotkb:D6W335|ensemblfungi:YOR340C intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C psi-mi:rpa43_yeast(display_long)|uniprotkb:RPA43(gene name)|psi-mi:RPA43(display_short)|uniprotkb:RRN12(gene name synonym)|uniprotkb:YOR340C(locus name)|uniprotkb:O6271(orf name)|uniprotkb:DNA-directed DNA-dependent RNA polymerase 36 kDa polypeptide(gene name synonym) psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320631|imex:IM-14275-612 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014985.1|sgd:S000005867|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772|ensemblfungi:YOR340C(gene)|ensemblfungi:YOR340C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR036898|interpro:IPR041178|interpro:IPR041901|rcsb pdb:2RF4|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|dip:DIP-5405N|mint:P46669 refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI psi-mi:"MI:0469"(intact) crc64:0CC6421AC3BBC641 crc64:C197FE85644DD0F8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I8xMWRrEe0PhCstGStK44rQD30Q559292 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 intact-crc:A3C80043627B4B7D|rigid:XU3kNetN3NioRgRWpzmLJhEyLFs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28007 uniprotkb:P53131 intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320642|imex:IM-14275-613 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131 psi-mi:"MI:0469"(intact) crc64:C197FE85644DD0F8 crc64:DA8A085EC50FF430 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 intact-crc:863A310AC007D0A4|rigid:kxoNDgpS6t6fLDu+1ii7Whd0hhM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53335 uniprotkb:P28007 intact:EBI-23652|uniprotkb:D6VV57|uniprotkb:Q8TG89|intact:EBI-33325|ensemblfungi:YGR280C intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C psi-mi:pxr1_yeast(display_long)|uniprotkb:PXR1(gene name)|psi-mi:PXR1(display_short)|uniprotkb:GNO1(gene name synonym)|uniprotkb:PinX1-related protein 1(gene name synonym)|uniprotkb:G-patch nucleolar protein(gene name synonym)|uniprotkb:YGR280C(locus name) psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320653|imex:IM-14275-614 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011796.1|sgd:S000003512|dip:DIP-4308N|mint:P53335|ensemblfungi:YGR280C(gene)|ensemblfungi:YGR280C_mRNA(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|interpro:IPR000467(D111/G-patch) refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI psi-mi:"MI:0469"(intact) crc64:D5AB6EB2C129922D crc64:C197FE85644DD0F8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SzQtp13uvK3KbuNHyZQPJxKMzwY559292 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 intact-crc:D67CA2E0419AE21F|rigid:v4lb65UX0mENJFZlgBnUQ0XIOYQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28007 uniprotkb:P53849 intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C intact:EBI-29244|uniprotkb:D6W0T8|ensemblfungi:YNL255C psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:gis2_yeast(display_long)|uniprotkb:GIS2(gene name)|psi-mi:GIS2(display_short)|uniprotkb:N0852(orf name)|uniprotkb:YNL255C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320675|imex:IM-14275-616 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI refseq:NP_014144.1|sgd:S000005199|dip:DIP-2669N|mint:P53849|ensemblfungi:YNL255C(gene)|ensemblfungi:YNL255C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045182"(translation regulator activity)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875 psi-mi:"MI:0469"(intact) crc64:C197FE85644DD0F8 crc64:E72696428F85CA3F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 rogid:kftHFJVi7QRZASmr4hLdALvleR4559292 intact-crc:68B7E57B4F4BE5CE|rigid:2Mc326NtwSrzhigwRXJxqFQsPOk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53551 uniprotkb:P28007 intact:EBI-8064|uniprotkb:Q6Q5R6|uniprotkb:D6W3P0|ensemblfungi:YPL127C intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C psi-mi:h1_yeast(display_long)|uniprotkb:HHO1(gene name)|psi-mi:HHO1(display_short)|uniprotkb:LPI17C(orf name)|uniprotkb:YPL127C(locus name) psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320664|imex:IM-14275-615 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015198.1|sgd:S000006048|mint:P53551|dip:DIP-6587N|ensemblfungi:YPL127C(gene)|ensemblfungi:YPL127C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0097100"(supercoiled DNA binding)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1UHM|rcsb pdb:1USS|rcsb pdb:1UST|rcsb pdb:1YQA refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI psi-mi:"MI:0469"(intact) crc64:B0C53AC186E49F96 crc64:C197FE85644DD0F8 figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dPMYSAq1Cr7pfGGNgb3GDp3LnsQ559292 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 intact-crc:5CB9A5E430637EB0|rigid:FEYAS+y2PVFjGfTs8xlKDOD0Gfg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28007 uniprotkb:P53874 intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C intact:EBI-19873|uniprotkb:D6W101|ensemblfungi:YNL186W psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:ubp10_yeast(display_long)|uniprotkb:UBP10(gene name)|psi-mi:UBP10(display_short)|uniprotkb:YNL186W(locus name)|uniprotkb:N1619(orf name)|uniprotkb:Ubiquitin-specific-processing protease 10(gene name synonym)|uniprotkb:Deubiquitinating enzyme 10(gene name synonym)|uniprotkb:Disrupter of telomere silencing protein 4(gene name synonym)|uniprotkb:Ubiquitin thioesterase 10(gene name synonym)|uniprotkb:DOT4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320686|imex:IM-14275-617 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI refseq:NP_014213.2|sgd:S000005130|ensemblfungi:YNL186W(gene)|ensemblfungi:YNL186W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0043596"(nuclear replication fork)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|rcsb pdb:6RR0|dip:DIP-6664N|mint:P53874 psi-mi:"MI:0469"(intact) crc64:C197FE85644DD0F8 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 rogid:Z1rRAI9RLgHeGd7QwLbrf51v5LY559292 intact-crc:27C250E9B8A22C8C|rigid:KLk88ANz5VrUT+uVjBv3BYT9Hxw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03532 uniprotkb:P28007 intact:EBI-8170|uniprotkb:D6W0B7|ensemblfungi:YMR290C intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C psi-mi:has1_yeast(display_long)|uniprotkb:YMR290C(locus name)|uniprotkb:HAS1(gene name)|psi-mi:HAS1(display_short)|uniprotkb:Helicase associated with SET1 protein 1(gene name synonym) psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320708|imex:IM-14275-619 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014017.1|sgd:S000004903|mint:Q03532|dip:DIP-4396N|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990417"(snoRNA release from pre-rRNA)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR025313|interpro:IPR027417|interpro:IPR044773|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|ensemblfungi:YMR290C(gene)|ensemblfungi:YMR290C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis) refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI psi-mi:"MI:0469"(intact) crc64:EE15D51A7F6BE1A2 crc64:C197FE85644DD0F8 figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5gSGDwuvbg7Vso4aCQdMZKUQdCI559292 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 intact-crc:1E73831FFAA13B3D|rigid:TMWeDMrKP8QICqi48TrPJK3mT/s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03525 uniprotkb:P28007 intact:EBI-27597|uniprotkb:Q7Z870|ensemblfungi:YMR269W|uniprotkb:D6W095 intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C psi-mi:tma23_yeast(display_long)|uniprotkb:YMR269W(locus name)|uniprotkb:YM8156.11(orf name)|uniprotkb:TMA23(gene name)|psi-mi:TMA23(display_short)|uniprotkb:YMR268W-A(orf name)|uniprotkb:23 kDa translation machinery-associated protein(gene name synonym) psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320697|imex:IM-14275-618 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR269W(gene)|ensemblfungi:YMR269W_mRNA(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0042274"(ribosomal small subunit biogenesis)|sgd:S000004882|refseq:NP_013996.2|dip:DIP-1965N|mint:Q03525 refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI psi-mi:"MI:0469"(intact) - crc64:C197FE85644DD0F8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:yJy9JnQUnYKqa7aOQ5yEeHcNEpI559292 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 intact-crc:D10477D62D6954CD|rigid:YhqLj9RINHEl/ZEyEPEtMpnwxmo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28007 uniprotkb:Q06205 intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C intact:EBI-6956|uniprotkb:D6VZ83|ensemblfungi:YLR449W psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:fkbp4_yeast(display_long)|uniprotkb:FPR4(gene name)|psi-mi:FPR4(display_short)|uniprotkb:YLR449W(locus name)|uniprotkb:L9324.3(orf name)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Histone proline isomerase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320719|imex:IM-14275-620 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI sgd:S000004441|refseq:NP_013554.3|dip:DIP-909N|mint:Q06205|ensemblfungi:YLR449W(gene)|ensemblfungi:YLR449W_mRNA(transcript)|go:"GO:0000412"(histone peptidyl-prolyl isomerization)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR023566|interpro:IPR041232|rcsb pdb:4BF8 psi-mi:"MI:0469"(intact) crc64:C197FE85644DD0F8 crc64:CF90C6714F04572E figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 rogid:rDmDSGEgRbtgkLBoJTzmzxxY7B4559292 intact-crc:CE420CAE0DF7FB0E|rigid:5cw5aM7vDOrEDBWMVhBNXtavtbI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12339 uniprotkb:P28007 intact:EBI-30231|uniprotkb:D6W270|ensemblfungi:YOR004W intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C psi-mi:utp23_yeast(display_long)|uniprotkb:U3 small nucleolar RNA-associated protein 23(gene name synonym)|uniprotkb:U three protein 23(gene name synonym)|uniprotkb:UTP23(gene name)|psi-mi:UTP23(display_short)|uniprotkb:YOR004W(locus name) psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320741|imex:IM-14275-622 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014646.1|sgd:S000005530|dip:DIP-4352N|mint:Q12339|ensemblfungi:YOR004W(gene)|ensemblfungi:YOR004W_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0032040"(small-subunit processome)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR006984(Protein of unknown function DUF652)|interpro:IPR029060|rcsb pdb:4MJ7 refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI psi-mi:"MI:0469"(intact) crc64:27D00C72F6B492F6 crc64:C197FE85644DD0F8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:OvURSlkfCuWUay/vbYqayjai9/A559292 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 intact-crc:FEC094EC6F59DA5D|rigid:NNP+g7iUcEMbTX+K3rjyCpifBlg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28007 uniprotkb:Q08235 intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C intact:EBI-3775|uniprotkb:D6W1Z1|ensemblfungi:YOL077C psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:brx1_yeast(display_long)|uniprotkb:YOL077C(locus name)|uniprotkb:BRX1(gene name)|psi-mi:BRX1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320730|imex:IM-14275-621 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI refseq:NP_014565.2|sgd:S000005437|dip:DIP-6317N|mint:Q08235|ensemblfungi:YOL077C(gene)|ensemblfungi:YOL077C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000464"("endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000465"("exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR007109(Brix)|interpro:IPR026532|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5 psi-mi:"MI:0469"(intact) crc64:C197FE85644DD0F8 crc64:31466853EF0E7301 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 rogid:mPR6HWKwM6RNCRE/vezsYlCmEGY559292 intact-crc:91D629EF39FA021F|rigid:vsCeni67qiyhiJp6kmM8Z2drtg4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6Q547 uniprotkb:P28007 intact:EBI-2052475|uniprotkb:D3DL22|ensemblfungi:YHR072W-A intact:EBI-7321|uniprotkb:D3DL41|ensemblfungi:YHR089C psi-mi:nop10_yeast(display_long)|uniprotkb:YHR072W-A(locus name)|uniprotkb:Nucleolar protein family A member 3(gene name synonym)|uniprotkb:snoRNP protein NOP10(gene name synonym)|uniprotkb:NOP10(gene name)|psi-mi:NOP10(display_short)|uniprotkb:Nucleolar protein 10(gene name synonym) psi-mi:gar1_yeast(display_long)|uniprotkb:YHR089C(locus name)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:snoRNP protein GAR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320752|imex:IM-14275-623 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058135.1|sgd:S000007455|dip:DIP-5845N|mint:Q6Q547|ensemblfungi:YHR072W-A(gene)|ensemblfungi:YHR072W-A_mRNA(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|interpro:IPR007264(Nucleolar RNA-binding protein Nop10p)|interpro:IPR036756|rcsb pdb:1Y2Y|rcsb pdb:2AQA|rcsb pdb:3U28|rcsb pdb:3UAI refseq:NP_011957.1|sgd:S000001131|mint:P28007|dip:DIP-4484N|ensemblfungi:YHR089C(gene)|ensemblfungi:YHR089C_mRNA(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0005730"(nucleolus)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|rcsb pdb:3U28|rcsb pdb:3UAI psi-mi:"MI:0469"(intact) crc64:4718D35AF7911FBA crc64:C197FE85644DD0F8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9m0x3DatObFwua2cbCQYMRKGqrU559292 rogid:wwYAG/cTAhO3HCX0PLnV0NXhWl4559292 intact-crc:FD7C811643142E43|rigid:5jK9TygAUt8znSNNomvHFgGbY4E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23542 uniprotkb:P28274 intact:EBI-2002|uniprotkb:D6VY29|ensemblfungi:YLR027C intact:EBI-20128|uniprotkb:D6VPW0|ensemblfungi:YBL039C psi-mi:aatc_yeast(display_long)|uniprotkb:AAT2(gene name)|psi-mi:AAT2(display_short)|uniprotkb:YLR027C(locus name)|uniprotkb:ASP5(gene name synonym)|uniprotkb:L1746(orf name)|uniprotkb:Transaminase A(gene name synonym) psi-mi:ura7_yeast(display_long)|uniprotkb:YBL039C(locus name)|uniprotkb:YBL0410(orf name)|uniprotkb:URA7(gene name)|psi-mi:URA7(display_short)|uniprotkb:UTP--ammonia ligase 1(gene name synonym)|uniprotkb:CTP synthetase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320763|imex:IM-14275-624 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013127.2|sgd:S000004017|dip:DIP-2897N|mint:P23542|go:"GO:0019266"(asparagine biosynthetic process from oxaloacetate)|go:"GO:0030170"(pyridoxal phosphate binding)|interpro:IPR000796(Aspartate/other aminotransferase)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:1YAA|reactome:R-SCE-70263|reactome:R-SCE-8963693|ensemblfungi:YLR027C(gene)|ensemblfungi:YLR027C_mRNA(transcript)|go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0006532"(aspartate biosynthetic process)|go:"GO:0006536"(glutamate metabolic process) refseq:NP_009514.1|sgd:S000000135|mint:P28274|ensemblfungi:YBL039C(gene)|ensemblfungi:YBL039C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0003883"(CTP synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0097268"(cytoophidium)|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|interpro:IPR033828|reactome:R-SCE-499943|dip:DIP-2954N psi-mi:"MI:0469"(intact) crc64:D25F40F6C6DD2B33 crc64:EC3766C83B22ED92 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:eNypS723YWwMMuWVVoTnidvQuaA559292 rogid:O/aH071giuopuWAjtGPdWti19NQ559292 intact-crc:5EB1811D2EA56963|rigid:1xg9av1o42w+w3Z0Pbr01pyfiH4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P28496 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-26585|uniprotkb:D6VXS8|ensemblfungi:YKL008C psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:lac1_yeast(display_long)|uniprotkb:LAC1(gene name)|psi-mi:LAC1(display_short)|uniprotkb:DGT1(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase LAC1(gene name synonym)|uniprotkb:YKL156(orf name)|uniprotkb:YKL008C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320785|imex:IM-14275-626 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 sgd:S000001491|refseq:NP_012917.3|mint:P28496|dip:DIP-4348N|ensemblfungi:YKL008C(gene)|ensemblfungi:YKL008C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0034399"(nuclear periphery)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:0061576"(acyl-CoA ceramide synthase complex)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR013599(TRAM1-like protein)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|reactome:R-SCE-1660661 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:gqRCCAHQcrRAHNO+R2LkQOzJ0mg559292 intact-crc:FE041A4D803A96F1|rigid:7x8eT+dQkpucuart5ybvAkeex7g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41811 uniprotkb:P28274 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W intact:EBI-20128|uniprotkb:D6VPW0|ensemblfungi:YBL039C psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:ura7_yeast(display_long)|uniprotkb:YBL039C(locus name)|uniprotkb:YBL0410(orf name)|uniprotkb:URA7(gene name)|psi-mi:URA7(display_short)|uniprotkb:UTP--ammonia ligase 1(gene name synonym)|uniprotkb:CTP synthetase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320774|imex:IM-14275-625 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_009514.1|sgd:S000000135|mint:P28274|ensemblfungi:YBL039C(gene)|ensemblfungi:YBL039C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0003883"(CTP synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0097268"(cytoophidium)|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|interpro:IPR033828|reactome:R-SCE-499943|dip:DIP-2954N psi-mi:"MI:0469"(intact) crc64:6A5E50BBEB02CB58 crc64:EC3766C83B22ED92 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 rogid:O/aH071giuopuWAjtGPdWti19NQ559292 intact-crc:AD363E8E2B45CBDF|rigid:0gwKdy0Z73aPoo/nljYns3LuLSY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28496 uniprotkb:P28496 intact:EBI-26585|uniprotkb:D6VXS8|ensemblfungi:YKL008C intact:EBI-26585|uniprotkb:D6VXS8|ensemblfungi:YKL008C psi-mi:lac1_yeast(display_long)|uniprotkb:LAC1(gene name)|psi-mi:LAC1(display_short)|uniprotkb:DGT1(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase LAC1(gene name synonym)|uniprotkb:YKL156(orf name)|uniprotkb:YKL008C(locus name) psi-mi:lac1_yeast(display_long)|uniprotkb:LAC1(gene name)|psi-mi:LAC1(display_short)|uniprotkb:DGT1(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase LAC1(gene name synonym)|uniprotkb:YKL156(orf name)|uniprotkb:YKL008C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320796|imex:IM-14275-627 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001491|refseq:NP_012917.3|mint:P28496|dip:DIP-4348N|ensemblfungi:YKL008C(gene)|ensemblfungi:YKL008C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0034399"(nuclear periphery)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:0061576"(acyl-CoA ceramide synthase complex)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR013599(TRAM1-like protein)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|reactome:R-SCE-1660661 sgd:S000001491|refseq:NP_012917.3|mint:P28496|dip:DIP-4348N|ensemblfungi:YKL008C(gene)|ensemblfungi:YKL008C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0034399"(nuclear periphery)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:0061576"(acyl-CoA ceramide synthase complex)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR013599(TRAM1-like protein)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|reactome:R-SCE-1660661 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:gqRCCAHQcrRAHNO+R2LkQOzJ0mg559292 rogid:gqRCCAHQcrRAHNO+R2LkQOzJ0mg559292 intact-crc:44225A456246012C|rigid:oCCT/1/n4Lmjy10SeJpvQIrj5Kw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28496 uniprotkb:P38703 intact:EBI-26585|uniprotkb:D6VXS8|ensemblfungi:YKL008C intact:EBI-10035|uniprotkb:Q6LD26|uniprotkb:D3DKR1|ensemblfungi:YHL003C psi-mi:lac1_yeast(display_long)|uniprotkb:LAC1(gene name)|psi-mi:LAC1(display_short)|uniprotkb:DGT1(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase LAC1(gene name synonym)|uniprotkb:YKL156(orf name)|uniprotkb:YKL008C(locus name) psi-mi:lag1_yeast(display_long)|uniprotkb:LAG1(gene name)|psi-mi:LAG1(display_short)|uniprotkb:Longevity assurance factor 1(gene name synonym)|uniprotkb:Longevity assurance protein 1(gene name synonym)|uniprotkb:Longevity assurance gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase LAG1(gene name synonym)|uniprotkb:YHL003C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320807|imex:IM-14275-628 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001491|refseq:NP_012917.3|mint:P28496|dip:DIP-4348N|ensemblfungi:YKL008C(gene)|ensemblfungi:YKL008C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0034399"(nuclear periphery)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:0061576"(acyl-CoA ceramide synthase complex)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR013599(TRAM1-like protein)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|reactome:R-SCE-1660661 refseq:NP_011860.1|sgd:S000000995|ensemblfungi:YHL003C(gene)|ensemblfungi:YHL003C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:0061576"(acyl-CoA ceramide synthase complex)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR013599(TRAM1-like protein)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|reactome:R-SCE-1660661|dip:DIP-4393N|mint:P38703 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:gqRCCAHQcrRAHNO+R2LkQOzJ0mg559292 rogid:KCAjx/gXmy0oGd3aKgasDuFHJzw559292 intact-crc:5EC1533385BA15BD|rigid:oUy/IHPQVgIYkKJ+L/AwQ58OfU0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28496 uniprotkb:P40350 intact:EBI-26585|uniprotkb:D6VXS8|ensemblfungi:YKL008C intact:EBI-2470|uniprotkb:D6W3E3|ensemblfungi:YPL227C psi-mi:lac1_yeast(display_long)|uniprotkb:LAC1(gene name)|psi-mi:LAC1(display_short)|uniprotkb:DGT1(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase LAC1(gene name synonym)|uniprotkb:YKL156(orf name)|uniprotkb:YKL008C(locus name) psi-mi:alg5_yeast(display_long)|uniprotkb:ALG5(gene name)|psi-mi:ALG5(display_short)|uniprotkb:YPL227C(locus name)|uniprotkb:P1437(orf name)|uniprotkb:Asparagine-linked glycosylation protein 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320818|imex:IM-14275-629 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001491|refseq:NP_012917.3|mint:P28496|dip:DIP-4348N|ensemblfungi:YKL008C(gene)|ensemblfungi:YKL008C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0034399"(nuclear periphery)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:0061576"(acyl-CoA ceramide synthase complex)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR013599(TRAM1-like protein)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|reactome:R-SCE-1660661 refseq:NP_015097.1|sgd:S000006148|dip:DIP-5651N|mint:P40350|ensemblfungi:YPL227C(gene)|ensemblfungi:YPL227C_mRNA(transcript)|go:"GO:0004581"(dolichyl-phosphate beta-glucosyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR035518|reactome:R-SCE-480985 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:gqRCCAHQcrRAHNO+R2LkQOzJ0mg559292 rogid:aKi97cbwqo7kNWhtRyzG3UOLH4U559292 intact-crc:7F1ADBD12FFA456B|rigid:lQsVosppHvU+QBwzDubR8ZRSP04 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28496 uniprotkb:Q04080 intact:EBI-26585|uniprotkb:D6VXS8|ensemblfungi:YKL008C intact:EBI-7777|uniprotkb:D6VT61|ensemblfungi:YDR434W psi-mi:lac1_yeast(display_long)|uniprotkb:LAC1(gene name)|psi-mi:LAC1(display_short)|uniprotkb:DGT1(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase LAC1(gene name synonym)|uniprotkb:YKL156(orf name)|uniprotkb:YKL008C(locus name) psi-mi:gpi17_yeast(display_long)|uniprotkb:GPI17(gene name)|psi-mi:GPI17(display_short)|uniprotkb:D9461.20(orf name)|uniprotkb:YDR434W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320840|imex:IM-14275-631 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001491|refseq:NP_012917.3|mint:P28496|dip:DIP-4348N|ensemblfungi:YKL008C(gene)|ensemblfungi:YKL008C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0034399"(nuclear periphery)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:0061576"(acyl-CoA ceramide synthase complex)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR013599(TRAM1-like protein)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|reactome:R-SCE-1660661 sgd:S000002842|interpro:IPR019540|refseq:NP_010722.3|mint:Q04080|ensemblfungi:YDR434W(gene)|ensemblfungi:YDR434W_mRNA(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:gqRCCAHQcrRAHNO+R2LkQOzJ0mg559292 rogid:7bBqUoVPfAOj/Pm4RPbzshzWNr0559292 intact-crc:4AE08B30769AA1A6|rigid:LvOZ2m9mAXtrY1HUmI3L3duQKHk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03049 uniprotkb:P28496 intact:EBI-35573|uniprotkb:D6VTG0|ensemblfungi:YDR541C intact:EBI-26585|uniprotkb:D6VXS8|ensemblfungi:YKL008C psi-mi:yd541_yeast(display_long)|uniprotkb:YDR541C(locus name) psi-mi:lac1_yeast(display_long)|uniprotkb:LAC1(gene name)|psi-mi:LAC1(display_short)|uniprotkb:DGT1(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase LAC1(gene name synonym)|uniprotkb:YKL156(orf name)|uniprotkb:YKL008C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320829|imex:IM-14275-630 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010830.4|sgd:S000002949|mint:Q03049|dip:DIP-5276N|ensemblfungi:YDR541C(gene)|ensemblfungi:YDR541C_mRNA(transcript)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0033721"("aldehyde dehydrogenase (NADP+) activity")|go:"GO:1901426"(response to furfural)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291 sgd:S000001491|refseq:NP_012917.3|mint:P28496|dip:DIP-4348N|ensemblfungi:YKL008C(gene)|ensemblfungi:YKL008C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0034399"(nuclear periphery)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:0061576"(acyl-CoA ceramide synthase complex)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR013599(TRAM1-like protein)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|reactome:R-SCE-1660661 psi-mi:"MI:0469"(intact) crc64:B920E3CD32531254 - figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RINBeahEIT2jY77XenTIYB9wnXU559292 rogid:gqRCCAHQcrRAHNO+R2LkQOzJ0mg559292 intact-crc:192E43CCFA458C27|rigid:St4RYlVy9GU32G5flqtLDzd1cWs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28737 uniprotkb:P0C268 intact:EBI-11435|ensemblfungi:YGR028W|uniprotkb:D6VUG3 intact:EBI-2044092|uniprotkb:D6VPV9|ensemblfungi:YBL039W-B psi-mi:msp1_yeast(display_long)|uniprotkb:MSP1(gene name)|psi-mi:MSP1(display_short)|uniprotkb:YTA4(gene name synonym)|uniprotkb:Tat-binding homolog 4(gene name synonym)|uniprotkb:YGR028W(locus name)|uniprotkb:Mitochondrial sorting of proteins(gene name synonym) psi-mi:yb39b_yeast(display_long)|uniprotkb:YBL039W-B(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320851|imex:IM-14275-632 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR028W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|ensemblfungi:YGR028W(gene)|go:"GO:0034214"(protein hexamerization)|go:"GO:0140567"(transmembrane protein dislocase activity)|go:"GO:0140570"(extraction of mislocalized protein from mitochondrial outer membrane)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:5W0T|reactome:R-SCE-9603798|refseq:NP_011542.3|sgd:S000003260|mint:P28737|dip:DIP-8029N sgd:S000028517|refseq:NP_878045.1|mint:P0C268|ensemblfungi:YBL039W-B(gene)|ensemblfungi:YBL039W-B_mRNA(transcript)|go:"GO:0005777"(peroxisome) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UFZA88NVrknmWX1JBM1aeE0xUt8559292 rogid:EfowKSHyZ6Fgw3vWQ74mzPwXTbQ559292 intact-crc:BA7D2EC4A5CBBF8A|rigid:vlnlxznKg1CIZWA01P8r9cRoF9Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28737 uniprotkb:P28737 intact:EBI-11435|ensemblfungi:YGR028W|uniprotkb:D6VUG3 intact:EBI-11435|ensemblfungi:YGR028W|uniprotkb:D6VUG3 psi-mi:msp1_yeast(display_long)|uniprotkb:MSP1(gene name)|psi-mi:MSP1(display_short)|uniprotkb:YTA4(gene name synonym)|uniprotkb:Tat-binding homolog 4(gene name synonym)|uniprotkb:YGR028W(locus name)|uniprotkb:Mitochondrial sorting of proteins(gene name synonym) psi-mi:msp1_yeast(display_long)|uniprotkb:MSP1(gene name)|psi-mi:MSP1(display_short)|uniprotkb:YTA4(gene name synonym)|uniprotkb:Tat-binding homolog 4(gene name synonym)|uniprotkb:YGR028W(locus name)|uniprotkb:Mitochondrial sorting of proteins(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320862|imex:IM-14275-633 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR028W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|ensemblfungi:YGR028W(gene)|go:"GO:0034214"(protein hexamerization)|go:"GO:0140567"(transmembrane protein dislocase activity)|go:"GO:0140570"(extraction of mislocalized protein from mitochondrial outer membrane)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:5W0T|reactome:R-SCE-9603798|refseq:NP_011542.3|sgd:S000003260|mint:P28737|dip:DIP-8029N ensemblfungi:YGR028W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|ensemblfungi:YGR028W(gene)|go:"GO:0034214"(protein hexamerization)|go:"GO:0140567"(transmembrane protein dislocase activity)|go:"GO:0140570"(extraction of mislocalized protein from mitochondrial outer membrane)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:5W0T|reactome:R-SCE-9603798|refseq:NP_011542.3|sgd:S000003260|mint:P28737|dip:DIP-8029N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UFZA88NVrknmWX1JBM1aeE0xUt8559292 rogid:UFZA88NVrknmWX1JBM1aeE0xUt8559292 intact-crc:75D1A8E3B6591B10|rigid:SH/KAxkVgOP//xZDwR9cFGfKAg8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28737 uniprotkb:P54783 intact:EBI-11435|ensemblfungi:YGR028W|uniprotkb:D6VUG3 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:msp1_yeast(display_long)|uniprotkb:MSP1(gene name)|psi-mi:MSP1(display_short)|uniprotkb:YTA4(gene name synonym)|uniprotkb:Tat-binding homolog 4(gene name synonym)|uniprotkb:YGR028W(locus name)|uniprotkb:Mitochondrial sorting of proteins(gene name synonym) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320873|imex:IM-14275-634 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR028W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|ensemblfungi:YGR028W(gene)|go:"GO:0034214"(protein hexamerization)|go:"GO:0140567"(transmembrane protein dislocase activity)|go:"GO:0140570"(extraction of mislocalized protein from mitochondrial outer membrane)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:5W0T|reactome:R-SCE-9603798|refseq:NP_011542.3|sgd:S000003260|mint:P28737|dip:DIP-8029N go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UFZA88NVrknmWX1JBM1aeE0xUt8559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:74A1740AC8934419|rigid:purHx0bjXfAYzxB4t2rIsKW4eto false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02969 uniprotkb:P28795 intact:EBI-37452|uniprotkb:Q6B2A9|uniprotkb:D6W3Q5|ensemblfungi:YPL112C intact:EBI-13164|uniprotkb:D6VSW1|ensemblfungi:YDR329C psi-mi:pex25_yeast(display_long)|uniprotkb:YPL112C(locus name)|uniprotkb:PEX25(gene name)|psi-mi:PEX25(display_short)|uniprotkb:Peroxin-25(gene name synonym) psi-mi:pex3_yeast(display_long)|uniprotkb:PEX3(gene name)|psi-mi:PEX3(display_short)|uniprotkb:PAS3(gene name synonym)|uniprotkb:YDR329C(locus name)|uniprotkb:D9798.15(orf name)|uniprotkb:Peroxin-3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320884|imex:IM-14275-635 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006033|refseq:NP_015213.1|dip:DIP-5292N|mint:Q02969|ensemblfungi:YPL112C(gene)|ensemblfungi:YPL112C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016559"(peroxisome fission)|go:"GO:0044375"(regulation of peroxisome size)|interpro:IPR008733(Peroxisomal biogenesis factor 11) sgd:S000002737|refseq:NP_010616.3|mint:P28795|dip:DIP-2477N|ensemblfungi:YDR329C(gene)|ensemblfungi:YDR329C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0045033"(peroxisome inheritance)|go:"GO:0045046"(protein import into peroxisome membrane)|interpro:IPR006966(Peroxin-3)|reactome:R-SCE-1369062|reactome:R-SCE-9603798 psi-mi:"MI:0469"(intact) - crc64:3CDC1D036DF0D0F9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:42Jce4KR0S5WehK1GVfqhG+Cqbo559292 rogid:YcXHJijTXVH0oLXYmqsvIT/OeV4559292 intact-crc:61C313299A9527A4|rigid:RkjHC3sHIXRvvhQQYa3JsBq5uLg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28795 uniprotkb:Q12462 intact:EBI-13164|uniprotkb:D6VSW1|ensemblfungi:YDR329C intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C psi-mi:pex3_yeast(display_long)|uniprotkb:PEX3(gene name)|psi-mi:PEX3(display_short)|uniprotkb:PAS3(gene name synonym)|uniprotkb:YDR329C(locus name)|uniprotkb:D9798.15(orf name)|uniprotkb:Peroxin-3(gene name synonym) psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320895|imex:IM-14275-636 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002737|refseq:NP_010616.3|mint:P28795|dip:DIP-2477N|ensemblfungi:YDR329C(gene)|ensemblfungi:YDR329C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0045033"(peroxisome inheritance)|go:"GO:0045046"(protein import into peroxisome membrane)|interpro:IPR006966(Peroxin-3)|reactome:R-SCE-1369062|reactome:R-SCE-9603798 refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) psi-mi:"MI:0469"(intact) crc64:3CDC1D036DF0D0F9 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YcXHJijTXVH0oLXYmqsvIT/OeV4559292 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 intact-crc:05B134B6FA1DA15F|rigid:zihClotj9bzsjHB/40lAMQy18Bo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29055 uniprotkb:P20434 intact:EBI-19123|uniprotkb:E9P939|uniprotkb:D6W488|ensemblfungi:YPR086W intact:EBI-15781|uniprotkb:Q02121|ensemblfungi:YBR154C|uniprotkb:D6VQE9 psi-mi:tf2b_yeast(display_long)|uniprotkb:SUA7(gene name)|psi-mi:SUA7(display_short)|uniprotkb:YPR086W(locus name)|uniprotkb:P9513.4(orf name)|uniprotkb:General transcription factor TFIIB(gene name synonym)|uniprotkb:Transcription factor E(gene name synonym) psi-mi:rpab1_yeast(display_long)|uniprotkb:RPB5(gene name)|psi-mi:RPB5(display_short)|uniprotkb:YBR154C(locus name)|uniprotkb:YBR1204(orf name)|uniprotkb:RPA7(gene name synonym)|uniprotkb:RPC9(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide(gene name synonym)|uniprotkb:ABC27(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320906|imex:IM-14275-637 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015411.1|sgd:S000006290|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0001174"(transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR000812(Transcription factor TFIIB related)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR013150(Transcription factor TFIIB, cyclin-related)|interpro:IPR013763(Cyclin-related)|interpro:IPR023486|interpro:IPR036915|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-674695|reactome:R-SCE-6807505|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-76042|ensemblfungi:YPR086W(gene)|ensemblfungi:YPR086W_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|dip:DIP-701N|mint:P29055 rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|rcsb pdb:1WCM|rcsb pdb:1Y1V|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|rcsb pdb:2B63|rcsb pdb:2B8K|interpro:IPR020608|interpro:IPR020609|rcsb pdb:2E2H|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:1DZF|rcsb pdb:1I3Q|rcsb pdb:2E2I|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:5M5Y|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6H67|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:2E2J|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|ensemblfungi:YBR154C(gene)|ensemblfungi:YBR154C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4V1M|rcsb pdb:2JA5|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2JA6|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:2JA7|rcsb pdb:3GTG|rcsb pdb:2JA8|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:2NVQ|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4YM7|rcsb pdb:5C3E|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5G5L|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6H68|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|rcsb pdb:6UQ2|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-77075|reactome:R-SCE-9018519|refseq:NP_009712.1|sgd:S000000358|dip:DIP-71N|mint:P20434 psi-mi:"MI:0469"(intact) crc64:8F1F6D24602436E2 crc64:2A15F7114D69D829 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Gb2nPPZHh6buihJQ7IadgM3esXY559292 rogid:j/jAJ2fXWf4ebK1aWTWrKERGUpM559292 intact-crc:E06146B8787E3FBD|rigid:FK1sOeBbX5XhgvDaIUfSX9299RY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29295 uniprotkb:P32590 intact:EBI-8536|uniprotkb:D6W3G5|ensemblfungi:YPL204W intact:EBI-8655|uniprotkb:D6VQG5|ensemblfungi:YBR169C psi-mi:hrr25_yeast(display_long)|uniprotkb:YPL204W(locus name)|uniprotkb:HRR25(gene name)|psi-mi:HRR25(display_short) psi-mi:hsp79_yeast(display_long)|uniprotkb:SSE2(gene name)|psi-mi:SSE2(display_short)|uniprotkb:HSP(gene name synonym)|uniprotkb:YBR169C(locus name)|uniprotkb:YBR1221(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320917|imex:IM-14275-638 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015120.1|sgd:S000006125|mint:P29295|dip:DIP-157N|ensemblfungi:YPL204W(gene)|ensemblfungi:YPL204W_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005816"(spindle pole body)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033551"(monopolin complex)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0106214"(regulation of vesicle fusion with Golgi apparatus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000785"(regulation of autophagosome assembly)|go:"GO:2001159"(regulation of protein localization by the Cvt pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR030509|rcsb pdb:4XHL|rcsb pdb:5CYZ|rcsb pdb:5CZO|reactome:R-SCE-204005|reactome:R-SCE-6791226|reactome:R-SCE-9013405 refseq:NP_009728.1|sgd:S000000373|mint:P32590|dip:DIP-4862N|ensemblfungi:YBR169C(gene)|ensemblfungi:YBR169C_mRNA(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0042026"(protein refolding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129 psi-mi:"MI:0469"(intact) crc64:C4D3107A470E8BAF crc64:D6BC9656D93895C2 figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tS44OZjZHYS5GJDZM43ljVtw9SA559292 rogid:OugvlU8M3Sa7gMKDffVZ0V2/jpg559292 intact-crc:711714F7968EB40E|rigid:rhHi8d0Jf6ca1Xd7suML9mMkxTY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12462 uniprotkb:P29340 intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C intact:EBI-19784|uniprotkb:D6VUR5|ensemblfungi:YGR133W psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:ubcx_yeast(display_long)|uniprotkb:PEX4(gene name)|psi-mi:PEX4(display_short)|uniprotkb:PAS2(gene name synonym)|uniprotkb:UBC10(gene name synonym)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Peroxin-4(gene name synonym)|uniprotkb:YGR133W(locus name)|uniprotkb:E2 ubiquitin-conjugating enzyme PEX4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320928|imex:IM-14275-639 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) refseq:NP_011649.1|sgd:S000003365|ensemblfungi:YGR133W(gene)|ensemblfungi:YGR133W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Y9M|rcsb pdb:2Y9P|rcsb pdb:4BWF|dip:DIP-4411N|mint:P29340 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 rogid:+rOg4RSLbF0lsoJHgzSe784ckiY559292 intact-crc:6F1F5FC18133FA75|rigid:cjmj0BN3zKDG8jCFZhBLs3wsZ9E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11433 uniprotkb:P29366 intact:EBI-4220|uniprotkb:D6VPH5|ensemblfungi:YAL041W intact:EBI-3508|uniprotkb:D6VQJ6|ensemblfungi:YBR200W psi-mi:cdc24_yeast(display_long)|uniprotkb:CLS4(gene name synonym)|uniprotkb:YAL041W(locus name)|uniprotkb:CDC24(gene name)|psi-mi:CDC24(display_short)|uniprotkb:Calcium regulatory protein(gene name synonym) psi-mi:bem1_yeast(display_long)|uniprotkb:Suppressor of RHO3 protein 1(gene name synonym)|uniprotkb:BEM1(gene name)|psi-mi:BEM1(display_short)|uniprotkb:SRO1(gene name synonym)|uniprotkb:YBR200W(locus name)|uniprotkb:YBR1412(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320939|imex:IM-14275-640 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009359.1|sgd:S000000039|dip:DIP-2228N|mint:P11433|ensemblfungi:YAL041W(gene)|ensemblfungi:YAL041W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000935"(division septum)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043577"(chemotropism)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010481(CDC24 calponin)|interpro:IPR033511|interpro:IPR035899|interpro:IPR036872|rcsb pdb:1PQS|rcsb pdb:1Q1O|rcsb pdb:1TZ1|rcsb pdb:2KFJ|rcsb pdb:2KFK sgd:S000000404|refseq:NP_009759.3|dip:DIP-688N|mint:P29366|ensemblfungi:YBR200W(gene)|ensemblfungi:YBR200W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030427"(site of polarized growth)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR030507|interpro:IPR035548|interpro:IPR035549|interpro:IPR035550|interpro:IPR036028|interpro:IPR036871|rcsb pdb:1IP9|rcsb pdb:1IPG|rcsb pdb:2CZO|rcsb pdb:2KFK|rcsb pdb:2RQV|rcsb pdb:2RQW|rcsb pdb:2V6V|reactome:R-SCE-5668599 psi-mi:"MI:0469"(intact) crc64:856BCAF4EB0A67D1 crc64:FB6C525AE9A19181 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Q9eflcLn4oOOeRZ4tTjHrPguDUc559292 rogid:Fq7WxTviE31ivPWGJoZO5DsUcdg559292 intact-crc:188C1F2BF00A62C0|rigid:3DWpBSdcUcxdkrnQitEqEpXyPO4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29366 uniprotkb:P29366 intact:EBI-3508|uniprotkb:D6VQJ6|ensemblfungi:YBR200W intact:EBI-3508|uniprotkb:D6VQJ6|ensemblfungi:YBR200W psi-mi:bem1_yeast(display_long)|uniprotkb:Suppressor of RHO3 protein 1(gene name synonym)|uniprotkb:BEM1(gene name)|psi-mi:BEM1(display_short)|uniprotkb:SRO1(gene name synonym)|uniprotkb:YBR200W(locus name)|uniprotkb:YBR1412(orf name) psi-mi:bem1_yeast(display_long)|uniprotkb:Suppressor of RHO3 protein 1(gene name synonym)|uniprotkb:BEM1(gene name)|psi-mi:BEM1(display_short)|uniprotkb:SRO1(gene name synonym)|uniprotkb:YBR200W(locus name)|uniprotkb:YBR1412(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320950|imex:IM-14275-641 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000404|refseq:NP_009759.3|dip:DIP-688N|mint:P29366|ensemblfungi:YBR200W(gene)|ensemblfungi:YBR200W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030427"(site of polarized growth)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR030507|interpro:IPR035548|interpro:IPR035549|interpro:IPR035550|interpro:IPR036028|interpro:IPR036871|rcsb pdb:1IP9|rcsb pdb:1IPG|rcsb pdb:2CZO|rcsb pdb:2KFK|rcsb pdb:2RQV|rcsb pdb:2RQW|rcsb pdb:2V6V|reactome:R-SCE-5668599 sgd:S000000404|refseq:NP_009759.3|dip:DIP-688N|mint:P29366|ensemblfungi:YBR200W(gene)|ensemblfungi:YBR200W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030427"(site of polarized growth)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR030507|interpro:IPR035548|interpro:IPR035549|interpro:IPR035550|interpro:IPR036028|interpro:IPR036871|rcsb pdb:1IP9|rcsb pdb:1IPG|rcsb pdb:2CZO|rcsb pdb:2KFK|rcsb pdb:2RQV|rcsb pdb:2RQW|rcsb pdb:2V6V|reactome:R-SCE-5668599 psi-mi:"MI:0469"(intact) crc64:FB6C525AE9A19181 crc64:FB6C525AE9A19181 figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Fq7WxTviE31ivPWGJoZO5DsUcdg559292 rogid:Fq7WxTviE31ivPWGJoZO5DsUcdg559292 intact-crc:4916DE2C121F2777|rigid:dfrHOZ8/ehb2Hu1lBya5WbYn+FM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29366 uniprotkb:P35735 intact:EBI-3508|uniprotkb:D6VQJ6|ensemblfungi:YBR200W intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:bem1_yeast(display_long)|uniprotkb:Suppressor of RHO3 protein 1(gene name synonym)|uniprotkb:BEM1(gene name)|psi-mi:BEM1(display_short)|uniprotkb:SRO1(gene name synonym)|uniprotkb:YBR200W(locus name)|uniprotkb:YBR1412(orf name) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320961|imex:IM-14275-642 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000404|refseq:NP_009759.3|dip:DIP-688N|mint:P29366|ensemblfungi:YBR200W(gene)|ensemblfungi:YBR200W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030427"(site of polarized growth)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR030507|interpro:IPR035548|interpro:IPR035549|interpro:IPR035550|interpro:IPR036028|interpro:IPR036871|rcsb pdb:1IP9|rcsb pdb:1IPG|rcsb pdb:2CZO|rcsb pdb:2KFK|rcsb pdb:2RQV|rcsb pdb:2RQW|rcsb pdb:2V6V|reactome:R-SCE-5668599 refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) crc64:FB6C525AE9A19181 - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Fq7WxTviE31ivPWGJoZO5DsUcdg559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:625346979C55D5E2|rigid:+ZtwrgqmexJp6TZASHVuyH1y104 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38041 uniprotkb:P29366 intact:EBI-3719|uniprotkb:D6VPR9|ensemblfungi:YBL085W intact:EBI-3508|uniprotkb:D6VQJ6|ensemblfungi:YBR200W psi-mi:bob1_yeast(display_long)|uniprotkb:BOI1(gene name)|psi-mi:BOI1(display_short)|uniprotkb:BOB1(gene name synonym)|uniprotkb:YBL085W(locus name)|uniprotkb:YBL0717(orf name)|uniprotkb:GIN7(gene name synonym)|uniprotkb:Growth inhibitory protein 7(gene name synonym)|uniprotkb:BEM1-binding protein(gene name synonym) psi-mi:bem1_yeast(display_long)|uniprotkb:Suppressor of RHO3 protein 1(gene name synonym)|uniprotkb:BEM1(gene name)|psi-mi:BEM1(display_short)|uniprotkb:SRO1(gene name synonym)|uniprotkb:YBR200W(locus name)|uniprotkb:YBR1412(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320972|imex:IM-14275-643 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009468.1|sgd:S000000181|dip:DIP-2226N|mint:P38041|ensemblfungi:YBL085W(gene)|ensemblfungi:YBL085W_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0001881"(receptor recycling)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007015"(actin filament organization)|go:"GO:0007032"(endosome organization)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0030427"(site of polarized growth)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043332"(mating projection tip)|go:"GO:0055037"(recycling endosome)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR035551|interpro:IPR036028 sgd:S000000404|refseq:NP_009759.3|dip:DIP-688N|mint:P29366|ensemblfungi:YBR200W(gene)|ensemblfungi:YBR200W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030427"(site of polarized growth)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR030507|interpro:IPR035548|interpro:IPR035549|interpro:IPR035550|interpro:IPR036028|interpro:IPR036871|rcsb pdb:1IP9|rcsb pdb:1IPG|rcsb pdb:2CZO|rcsb pdb:2KFK|rcsb pdb:2RQV|rcsb pdb:2RQW|rcsb pdb:2V6V|reactome:R-SCE-5668599 psi-mi:"MI:0469"(intact) - crc64:FB6C525AE9A19181 figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WcK0gGhMeNGTOtDIXkYjqtOuLl4559292 rogid:Fq7WxTviE31ivPWGJoZO5DsUcdg559292 intact-crc:3A26F2BD55D1177A|rigid:YS98rzCoUbRLbILi8ecxNvjri24 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29366 uniprotkb:P89102 intact:EBI-3508|uniprotkb:D6VQJ6|ensemblfungi:YBR200W intact:EBI-16865|uniprotkb:Q03775|uniprotkb:Q04128|uniprotkb:D6VSE6|ensemblfungi:YDR166C psi-mi:bem1_yeast(display_long)|uniprotkb:Suppressor of RHO3 protein 1(gene name synonym)|uniprotkb:BEM1(gene name)|psi-mi:BEM1(display_short)|uniprotkb:SRO1(gene name synonym)|uniprotkb:YBR200W(locus name)|uniprotkb:YBR1412(orf name) psi-mi:sec5_yeast(display_long)|uniprotkb:YD8358.20C(orf name)|uniprotkb:SEC5(gene name)|psi-mi:SEC5(display_short)|uniprotkb:YD9489.01C(orf name)|uniprotkb:YDR166C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320983|imex:IM-14275-644 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000404|refseq:NP_009759.3|dip:DIP-688N|mint:P29366|ensemblfungi:YBR200W(gene)|ensemblfungi:YBR200W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030427"(site of polarized growth)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR030507|interpro:IPR035548|interpro:IPR035549|interpro:IPR035550|interpro:IPR036028|interpro:IPR036871|rcsb pdb:1IP9|rcsb pdb:1IPG|rcsb pdb:2CZO|rcsb pdb:2KFK|rcsb pdb:2RQV|rcsb pdb:2RQW|rcsb pdb:2V6V|reactome:R-SCE-5668599 refseq:NP_010450.3|ensemblfungi:YDR166C(gene)|ensemblfungi:YDR166C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000145"(exocyst)|go:"GO:0001927"(exocyst assembly)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0043332"(mating projection tip)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0071944"(cell periphery)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR029175|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876|interpro:IPR039481|sgd:S000002573|dip:DIP-2579N|mint:P89102 psi-mi:"MI:0469"(intact) crc64:FB6C525AE9A19181 - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Fq7WxTviE31ivPWGJoZO5DsUcdg559292 rogid:SWV3HuxYf2DehDadp3hAPEELUTU559292 intact-crc:D2303E640C746374|rigid:Fg8VCpEAIbY+q6QF6+xW2Uabur0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03497 uniprotkb:P29366 intact:EBI-18285|uniprotkb:D3DKQ8|ensemblfungi:YHL007C intact:EBI-3508|uniprotkb:D6VQJ6|ensemblfungi:YBR200W psi-mi:ste20_yeast(display_long)|uniprotkb:STE20(gene name)|psi-mi:STE20(display_short)|uniprotkb:YHL007C(locus name) psi-mi:bem1_yeast(display_long)|uniprotkb:Suppressor of RHO3 protein 1(gene name synonym)|uniprotkb:BEM1(gene name)|psi-mi:BEM1(display_short)|uniprotkb:SRO1(gene name synonym)|uniprotkb:YBR200W(locus name)|uniprotkb:YBR1412(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6320994|imex:IM-14275-645 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011856.1|sgd:S000000999|ensemblfungi:YHL007C(gene)|ensemblfungi:YHL007C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|reactome:R-SCE-389359|interpro:IPR036936|reactome:R-SCE-5627123|reactome:R-SCE-5687128|reactome:R-SCE-9013405|reactome:R-SCE-9013406|rcsb pdb:2KYM|rcsb pdb:2LCS|rcsb pdb:2RQW|reactome:R-SCE-2029482|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035376"(sterol import)|go:"GO:0035404"(histone-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044025"("histone kinase activity (H2B-S14 specific)")|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|dip:DIP-712N|mint:Q03497 sgd:S000000404|refseq:NP_009759.3|dip:DIP-688N|mint:P29366|ensemblfungi:YBR200W(gene)|ensemblfungi:YBR200W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030427"(site of polarized growth)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR030507|interpro:IPR035548|interpro:IPR035549|interpro:IPR035550|interpro:IPR036028|interpro:IPR036871|rcsb pdb:1IP9|rcsb pdb:1IPG|rcsb pdb:2CZO|rcsb pdb:2KFK|rcsb pdb:2RQV|rcsb pdb:2RQW|rcsb pdb:2V6V|reactome:R-SCE-5668599 psi-mi:"MI:0469"(intact) crc64:69C1C12F5B87733C crc64:FB6C525AE9A19181 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ammX6PwJCeyVjNxJ2UJUBrZt9mM559292 rogid:Fq7WxTviE31ivPWGJoZO5DsUcdg559292 intact-crc:24B37102901D3DA4|rigid:QCJqHrvfSXBiFYAe6jPo48g8k5Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29465 uniprotkb:P09620 intact:EBI-4632|uniprotkb:D6VQ25|ensemblfungi:YBR023C intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:chs3_yeast(display_long)|uniprotkb:CHS3(gene name)|psi-mi:CHS3(display_short)|uniprotkb:CAL1(gene name synonym)|uniprotkb:DIT101(gene name synonym)|uniprotkb:KIT2(gene name synonym)|uniprotkb:YBR023C(locus name)|uniprotkb:CSD2(gene name synonym)|uniprotkb:YBR0305(orf name)|uniprotkb:Chitin-UDP acetyl-glucosaminyl transferase 3(gene name synonym)|uniprotkb:Class-IV chitin synthase 3(gene name synonym) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321005|imex:IM-14275-646 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009579.1|sgd:S000000227|dip:DIP-2482N|mint:P29465|ensemblfungi:YBR023C(gene)|ensemblfungi:YBR023C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0004100"(chitin synthase activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030428"(cell septum)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0045009"(chitosome)|go:"GO:0071944"(cell periphery)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR004835(Fungal chitin synthase)|interpro:IPR029044|rcsb pdb:4WJW ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8Ik0u35UXSJVtqfgNdo49J+nzFk559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:C504DB840DDAF7B2|rigid:b3oT45ulsrVCMM91DPjKK+C4BPI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29465 uniprotkb:P13134 intact:EBI-4632|uniprotkb:D6VQ25|ensemblfungi:YBR023C intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5 psi-mi:chs3_yeast(display_long)|uniprotkb:CHS3(gene name)|psi-mi:CHS3(display_short)|uniprotkb:CAL1(gene name synonym)|uniprotkb:DIT101(gene name synonym)|uniprotkb:KIT2(gene name synonym)|uniprotkb:YBR023C(locus name)|uniprotkb:CSD2(gene name synonym)|uniprotkb:YBR0305(orf name)|uniprotkb:Chitin-UDP acetyl-glucosaminyl transferase 3(gene name synonym)|uniprotkb:Class-IV chitin synthase 3(gene name synonym) psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321016|imex:IM-14275-647 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009579.1|sgd:S000000227|dip:DIP-2482N|mint:P29465|ensemblfungi:YBR023C(gene)|ensemblfungi:YBR023C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0004100"(chitin synthase activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030428"(cell septum)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0045009"(chitosome)|go:"GO:0071944"(cell periphery)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR004835(Fungal chitin synthase)|interpro:IPR029044|rcsb pdb:4WJW interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134 psi-mi:"MI:0469"(intact) - crc64:5DCEEDADCF439C78 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8Ik0u35UXSJVtqfgNdo49J+nzFk559292 rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292 intact-crc:CD5EA7B39D9EF1DB|rigid:waFKBong/vcDI3jXyqycBLOZ7/I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32660 uniprotkb:P29465 intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W intact:EBI-4632|uniprotkb:D6VQ25|ensemblfungi:YBR023C psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:chs3_yeast(display_long)|uniprotkb:CHS3(gene name)|psi-mi:CHS3(display_short)|uniprotkb:CAL1(gene name synonym)|uniprotkb:DIT101(gene name synonym)|uniprotkb:KIT2(gene name synonym)|uniprotkb:YBR023C(locus name)|uniprotkb:CSD2(gene name synonym)|uniprotkb:YBR0305(orf name)|uniprotkb:Chitin-UDP acetyl-glucosaminyl transferase 3(gene name synonym)|uniprotkb:Class-IV chitin synthase 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321027|imex:IM-14275-648 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) refseq:NP_009579.1|sgd:S000000227|dip:DIP-2482N|mint:P29465|ensemblfungi:YBR023C(gene)|ensemblfungi:YBR023C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0004100"(chitin synthase activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030428"(cell septum)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0045009"(chitosome)|go:"GO:0071944"(cell periphery)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR004835(Fungal chitin synthase)|interpro:IPR029044|rcsb pdb:4WJW psi-mi:"MI:0469"(intact) crc64:3CC3FBA8ADDE8960 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 rogid:8Ik0u35UXSJVtqfgNdo49J+nzFk559292 intact-crc:2DCF40F473409A65|rigid:vaJBJPZ+rBb7MPU7+hNEvkHCqRY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38843 uniprotkb:P29465 intact:EBI-24756|uniprotkb:D3DL91|ensemblfungi:YHR142W intact:EBI-4632|uniprotkb:D6VQ25|ensemblfungi:YBR023C psi-mi:chs7_yeast(display_long)|uniprotkb:YHR142W(locus name)|uniprotkb:CHS7(gene name)|psi-mi:CHS7(display_short) psi-mi:chs3_yeast(display_long)|uniprotkb:CHS3(gene name)|psi-mi:CHS3(display_short)|uniprotkb:CAL1(gene name synonym)|uniprotkb:DIT101(gene name synonym)|uniprotkb:KIT2(gene name synonym)|uniprotkb:YBR023C(locus name)|uniprotkb:CSD2(gene name synonym)|uniprotkb:YBR0305(orf name)|uniprotkb:Chitin-UDP acetyl-glucosaminyl transferase 3(gene name synonym)|uniprotkb:Class-IV chitin synthase 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321049|imex:IM-14275-650 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012011.1|sgd:S000001184|mint:P38843|dip:DIP-5238N|ensemblfungi:YHR142W(gene)|ensemblfungi:YHR142W_mRNA(transcript)|go:"GO:0005628"(prospore membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071555"(cell wall organization)|interpro:IPR022057 refseq:NP_009579.1|sgd:S000000227|dip:DIP-2482N|mint:P29465|ensemblfungi:YBR023C(gene)|ensemblfungi:YBR023C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0004100"(chitin synthase activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030428"(cell septum)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0045009"(chitosome)|go:"GO:0071944"(cell periphery)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR004835(Fungal chitin synthase)|interpro:IPR029044|rcsb pdb:4WJW psi-mi:"MI:0469"(intact) crc64:9DA1EAFA181B2409 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pyFq5p7Vk1l+5RhYA6CuqZeLl3c559292 rogid:8Ik0u35UXSJVtqfgNdo49J+nzFk559292 intact-crc:94523B9488BD1EDB|rigid:EQfiEjBamP1yQGRhDmdSKgatwI8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29465 uniprotkb:P38125 intact:EBI-4632|uniprotkb:D6VQ25|ensemblfungi:YBR023C intact:EBI-20904|uniprotkb:D6VQH4|ensemblfungi:YBR180W psi-mi:chs3_yeast(display_long)|uniprotkb:CHS3(gene name)|psi-mi:CHS3(display_short)|uniprotkb:CAL1(gene name synonym)|uniprotkb:DIT101(gene name synonym)|uniprotkb:KIT2(gene name synonym)|uniprotkb:YBR023C(locus name)|uniprotkb:CSD2(gene name synonym)|uniprotkb:YBR0305(orf name)|uniprotkb:Chitin-UDP acetyl-glucosaminyl transferase 3(gene name synonym)|uniprotkb:Class-IV chitin synthase 3(gene name synonym) psi-mi:dtr1_yeast(display_long)|uniprotkb:YBR1242(orf name)|uniprotkb:YBR180W(locus name)|uniprotkb:DTR1(gene name)|psi-mi:DTR1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321038|imex:IM-14275-649 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009579.1|sgd:S000000227|dip:DIP-2482N|mint:P29465|ensemblfungi:YBR023C(gene)|ensemblfungi:YBR023C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0004100"(chitin synthase activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030428"(cell septum)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0045009"(chitosome)|go:"GO:0071944"(cell periphery)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR004835(Fungal chitin synthase)|interpro:IPR029044|rcsb pdb:4WJW refseq:NP_009739.1|sgd:S000000384|mint:P38125|ensemblfungi:YBR180W(gene)|ensemblfungi:YBR180W_mRNA(transcript)|go:"GO:0005275"(amine transmembrane transporter activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0015837"(amine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|dip:DIP-5179N psi-mi:"MI:0469"(intact) - crc64:8175C30520A266F4 figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8Ik0u35UXSJVtqfgNdo49J+nzFk559292 rogid:OByEwC9qaRmw2J4Omi/6KnmTva4559292 intact-crc:C7D9411BD3FFE8B2|rigid:7s2gAj4Ryd/EfUrwxg8+TQxbz6w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39524 uniprotkb:P29465 intact:EBI-3106|uniprotkb:D6VPJ2|ensemblfungi:YAL026C intact:EBI-4632|uniprotkb:D6VQ25|ensemblfungi:YBR023C psi-mi:atc3_yeast(display_long)|uniprotkb:DRS2(gene name)|psi-mi:DRS2(display_short)|uniprotkb:FUN38(orf name)|uniprotkb:YAL026C(locus name) psi-mi:chs3_yeast(display_long)|uniprotkb:CHS3(gene name)|psi-mi:CHS3(display_short)|uniprotkb:CAL1(gene name synonym)|uniprotkb:DIT101(gene name synonym)|uniprotkb:KIT2(gene name synonym)|uniprotkb:YBR023C(locus name)|uniprotkb:CSD2(gene name synonym)|uniprotkb:YBR0305(orf name)|uniprotkb:Chitin-UDP acetyl-glucosaminyl transferase 3(gene name synonym)|uniprotkb:Class-IV chitin synthase 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321060|imex:IM-14275-651 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009376.2|sgd:S000000024|dip:DIP-2216N|mint:P39524|ensemblfungi:YAL026C(gene)|ensemblfungi:YAL026C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|go:"GO:1990530"(Cdc50p-Drs2p complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:6PSX|rcsb pdb:6PSY|rcsb pdb:6ROH|rcsb pdb:6ROI|rcsb pdb:6ROJ|rcsb pdb:7OH4|rcsb pdb:7OH5|rcsb pdb:7OH6|rcsb pdb:7OH7|reactome:R-SCE-6798695|reactome:R-SCE-936837 refseq:NP_009579.1|sgd:S000000227|dip:DIP-2482N|mint:P29465|ensemblfungi:YBR023C(gene)|ensemblfungi:YBR023C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0004100"(chitin synthase activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030428"(cell septum)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0045009"(chitosome)|go:"GO:0071944"(cell periphery)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR004835(Fungal chitin synthase)|interpro:IPR029044|rcsb pdb:4WJW psi-mi:"MI:0469"(intact) crc64:5745B92901F8E1AE - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:qJ8uK7dznIqyjVwjbw/VGn5Bo+4559292 rogid:8Ik0u35UXSJVtqfgNdo49J+nzFk559292 intact-crc:8A9D119662280712|rigid:BdHzsMDzRplD57jMYC2KWuLKKXI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29465 uniprotkb:P39719 intact:EBI-4632|uniprotkb:D6VQ25|ensemblfungi:YBR023C intact:EBI-20703|uniprotkb:Q05165|uniprotkb:D6VPG5|ensemblfungi:YAL053W psi-mi:chs3_yeast(display_long)|uniprotkb:CHS3(gene name)|psi-mi:CHS3(display_short)|uniprotkb:CAL1(gene name synonym)|uniprotkb:DIT101(gene name synonym)|uniprotkb:KIT2(gene name synonym)|uniprotkb:YBR023C(locus name)|uniprotkb:CSD2(gene name synonym)|uniprotkb:YBR0305(orf name)|uniprotkb:Chitin-UDP acetyl-glucosaminyl transferase 3(gene name synonym)|uniprotkb:Class-IV chitin synthase 3(gene name synonym) psi-mi:flc2_yeast(display_long)|uniprotkb:YAL053W(locus name)|uniprotkb:FLC2(gene name)|psi-mi:FLC2(display_short)|uniprotkb:FAD transporter 2(gene name synonym)|uniprotkb:TRP-like ion channel FLC2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321071|imex:IM-14275-652 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009579.1|sgd:S000000227|dip:DIP-2482N|mint:P29465|ensemblfungi:YBR023C(gene)|ensemblfungi:YBR023C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0004100"(chitin synthase activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030428"(cell septum)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0045009"(chitosome)|go:"GO:0071944"(cell periphery)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR004835(Fungal chitin synthase)|interpro:IPR029044|rcsb pdb:4WJW refseq:NP_009348.2|sgd:S000000049|ensemblfungi:YAL053W(gene)|ensemblfungi:YAL053W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241|go:"GO:0055085"(transmembrane transport)|dip:DIP-6708N|mint:P39719 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8Ik0u35UXSJVtqfgNdo49J+nzFk559292 rogid:NOmMW54DNa0o7vM945DlZgVUy44559292 intact-crc:3B4A1B76838D85B8|rigid:EutCs+HVRMmA89zo3e6G9vb3szU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43621 uniprotkb:P29465 intact:EBI-4876|uniprotkb:D6VTT4|ensemblfungi:YFR051C intact:EBI-4632|uniprotkb:D6VQ25|ensemblfungi:YBR023C psi-mi:copd_yeast(display_long)|uniprotkb:RET2(gene name)|psi-mi:RET2(display_short)|uniprotkb:YFR051C(locus name)|uniprotkb:Delta-coat protein(gene name synonym) psi-mi:chs3_yeast(display_long)|uniprotkb:CHS3(gene name)|psi-mi:CHS3(display_short)|uniprotkb:CAL1(gene name synonym)|uniprotkb:DIT101(gene name synonym)|uniprotkb:KIT2(gene name synonym)|uniprotkb:YBR023C(locus name)|uniprotkb:CSD2(gene name synonym)|uniprotkb:YBR0305(orf name)|uniprotkb:Chitin-UDP acetyl-glucosaminyl transferase 3(gene name synonym)|uniprotkb:Class-IV chitin synthase 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321082|imex:IM-14275-653 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001947|refseq:NP_116709.3|dip:DIP-5255N|mint:P43621|ensemblfungi:YFR051C(gene)|ensemblfungi:YFR051C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|rcsb pdb:5FJW|rcsb pdb:5FJX|rcsb pdb:5FJZ|rcsb pdb:5FK0|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_009579.1|sgd:S000000227|dip:DIP-2482N|mint:P29465|ensemblfungi:YBR023C(gene)|ensemblfungi:YBR023C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0004100"(chitin synthase activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030428"(cell septum)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0045009"(chitosome)|go:"GO:0071944"(cell periphery)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR004835(Fungal chitin synthase)|interpro:IPR029044|rcsb pdb:4WJW psi-mi:"MI:0469"(intact) crc64:AA730F046655EE5A - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:auvjuT8ffm1R4P3mRKEIWAsynW0559292 rogid:8Ik0u35UXSJVtqfgNdo49J+nzFk559292 intact-crc:CD39C217E907029F|rigid:+vMrmfmavnGKq/v7geZjTOV3tJI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08967 uniprotkb:P29465 intact:EBI-36673|uniprotkb:D6W3E9|ensemblfungi:YPL221W intact:EBI-4632|uniprotkb:D6VQ25|ensemblfungi:YBR023C psi-mi:flc1_yeast(display_long)|uniprotkb:FAD transporter 1(gene name synonym)|uniprotkb:FLC1(gene name)|psi-mi:FLC1(display_short)|uniprotkb:TRP-like ion channel protein FLC1(gene name synonym)|uniprotkb:Heme utilization factor 1(gene name synonym)|uniprotkb:Bypass of PAM1 protein 1(gene name synonym)|uniprotkb:HUF1(gene name synonym)|uniprotkb:YPL221W(locus name)|uniprotkb:BOP1(gene name synonym) psi-mi:chs3_yeast(display_long)|uniprotkb:CHS3(gene name)|psi-mi:CHS3(display_short)|uniprotkb:CAL1(gene name synonym)|uniprotkb:DIT101(gene name synonym)|uniprotkb:KIT2(gene name synonym)|uniprotkb:YBR023C(locus name)|uniprotkb:CSD2(gene name synonym)|uniprotkb:YBR0305(orf name)|uniprotkb:Chitin-UDP acetyl-glucosaminyl transferase 3(gene name synonym)|uniprotkb:Class-IV chitin synthase 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321093|imex:IM-14275-654 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015103.1|sgd:S000006142|mint:Q08967|dip:DIP-3965N|ensemblfungi:YPL221W(gene)|ensemblfungi:YPL221W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055085"(transmembrane transport)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241 refseq:NP_009579.1|sgd:S000000227|dip:DIP-2482N|mint:P29465|ensemblfungi:YBR023C(gene)|ensemblfungi:YBR023C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0004100"(chitin synthase activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030428"(cell septum)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0045009"(chitosome)|go:"GO:0071944"(cell periphery)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR004835(Fungal chitin synthase)|interpro:IPR029044|rcsb pdb:4WJW psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:r6CcZGEjxHUk2w0iBUBvnAPaFd4559292 rogid:8Ik0u35UXSJVtqfgNdo49J+nzFk559292 intact-crc:C6F914EFE9950EA1|rigid:7l0+GozxqqUTzmAy+F8ENlk1bZY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12057 uniprotkb:P29465 intact:EBI-29838|uniprotkb:D6W2G4|ensemblfungi:YOR104W intact:EBI-4632|uniprotkb:D6VQ25|ensemblfungi:YBR023C psi-mi:pin2_yeast(display_long)|uniprotkb:PIN2(gene name)|psi-mi:PIN2(display_short)|uniprotkb:YOR3214W(orf name)|uniprotkb:YOR104W(locus name) psi-mi:chs3_yeast(display_long)|uniprotkb:CHS3(gene name)|psi-mi:CHS3(display_short)|uniprotkb:CAL1(gene name synonym)|uniprotkb:DIT101(gene name synonym)|uniprotkb:KIT2(gene name synonym)|uniprotkb:YBR023C(locus name)|uniprotkb:CSD2(gene name synonym)|uniprotkb:YBR0305(orf name)|uniprotkb:Chitin-UDP acetyl-glucosaminyl transferase 3(gene name synonym)|uniprotkb:Class-IV chitin synthase 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321104|imex:IM-14275-655 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005630|refseq:NP_014747.1|dip:DIP-4459N|mint:Q12057|ensemblfungi:YOR104W(gene)|ensemblfungi:YOR104W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|interpro:IPR037504 refseq:NP_009579.1|sgd:S000000227|dip:DIP-2482N|mint:P29465|ensemblfungi:YBR023C(gene)|ensemblfungi:YBR023C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0004100"(chitin synthase activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030428"(cell septum)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0045009"(chitosome)|go:"GO:0071944"(cell periphery)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR004835(Fungal chitin synthase)|interpro:IPR029044|rcsb pdb:4WJW psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Zk6iUcpP++MEXuhKZ79TMOYQYqM559292 rogid:8Ik0u35UXSJVtqfgNdo49J+nzFk559292 intact-crc:E3A9EA90341A6E57|rigid:6vQXSkckXECrZW+z3GRnSVoROv8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:P30605 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-2050956|uniprotkb:D6VTB9|ensemblfungi:YDR497C psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:itr1_yeast(display_long)|uniprotkb:D9719.3(orf name)|uniprotkb:YDR497C(locus name)|uniprotkb:ITR1(gene name)|psi-mi:ITR1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321115|imex:IM-14275-656 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) refseq:NP_010785.1|sgd:S000002905|dip:DIP-7406N|mint:P30605|ensemblfungi:YDR497C(gene)|ensemblfungi:YDR497C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:GgtK4YFe7ZCZcmVpV5q1KY2F0Ds559292 intact-crc:08AA26CFBB89C790|rigid:LiFeioVsHdXRbWMROLmlCQPyCRA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30605 uniprotkb:P30605 intact:EBI-2050956|uniprotkb:D6VTB9|ensemblfungi:YDR497C intact:EBI-2050956|uniprotkb:D6VTB9|ensemblfungi:YDR497C psi-mi:itr1_yeast(display_long)|uniprotkb:D9719.3(orf name)|uniprotkb:YDR497C(locus name)|uniprotkb:ITR1(gene name)|psi-mi:ITR1(display_short) psi-mi:itr1_yeast(display_long)|uniprotkb:D9719.3(orf name)|uniprotkb:YDR497C(locus name)|uniprotkb:ITR1(gene name)|psi-mi:ITR1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321126|imex:IM-14275-657 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010785.1|sgd:S000002905|dip:DIP-7406N|mint:P30605|ensemblfungi:YDR497C(gene)|ensemblfungi:YDR497C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 refseq:NP_010785.1|sgd:S000002905|dip:DIP-7406N|mint:P30605|ensemblfungi:YDR497C(gene)|ensemblfungi:YDR497C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GgtK4YFe7ZCZcmVpV5q1KY2F0Ds559292 rogid:GgtK4YFe7ZCZcmVpV5q1KY2F0Ds559292 intact-crc:F701FB491D29861C|rigid:pNNutv5HL4tXqJ7JNj/RPN+pU28 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:P30605 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-2050956|uniprotkb:D6VTB9|ensemblfungi:YDR497C psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:itr1_yeast(display_long)|uniprotkb:D9719.3(orf name)|uniprotkb:YDR497C(locus name)|uniprotkb:ITR1(gene name)|psi-mi:ITR1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321137|imex:IM-14275-658 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N refseq:NP_010785.1|sgd:S000002905|dip:DIP-7406N|mint:P30605|ensemblfungi:YDR497C(gene)|ensemblfungi:YDR497C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:GgtK4YFe7ZCZcmVpV5q1KY2F0Ds559292 intact-crc:08A8B944B664DAEC|rigid:eNU9SHJqC9obt9p5zIGH9pE+fB8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38234 uniprotkb:P30605 intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C intact:EBI-2050956|uniprotkb:D6VTB9|ensemblfungi:YDR497C psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:itr1_yeast(display_long)|uniprotkb:D9719.3(orf name)|uniprotkb:YDR497C(locus name)|uniprotkb:ITR1(gene name)|psi-mi:ITR1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321148|imex:IM-14275-659 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 refseq:NP_010785.1|sgd:S000002905|dip:DIP-7406N|mint:P30605|ensemblfungi:YDR497C(gene)|ensemblfungi:YDR497C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 rogid:GgtK4YFe7ZCZcmVpV5q1KY2F0Ds559292 intact-crc:5BE7CF6BB6726254|rigid:MqyYybqr4iMrzCpL7W5lcUuQpak false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30605 uniprotkb:P39719 intact:EBI-2050956|uniprotkb:D6VTB9|ensemblfungi:YDR497C intact:EBI-20703|uniprotkb:Q05165|uniprotkb:D6VPG5|ensemblfungi:YAL053W psi-mi:itr1_yeast(display_long)|uniprotkb:D9719.3(orf name)|uniprotkb:YDR497C(locus name)|uniprotkb:ITR1(gene name)|psi-mi:ITR1(display_short) psi-mi:flc2_yeast(display_long)|uniprotkb:YAL053W(locus name)|uniprotkb:FLC2(gene name)|psi-mi:FLC2(display_short)|uniprotkb:FAD transporter 2(gene name synonym)|uniprotkb:TRP-like ion channel FLC2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321159|imex:IM-14275-660 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010785.1|sgd:S000002905|dip:DIP-7406N|mint:P30605|ensemblfungi:YDR497C(gene)|ensemblfungi:YDR497C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 refseq:NP_009348.2|sgd:S000000049|ensemblfungi:YAL053W(gene)|ensemblfungi:YAL053W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241|go:"GO:0055085"(transmembrane transport)|dip:DIP-6708N|mint:P39719 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GgtK4YFe7ZCZcmVpV5q1KY2F0Ds559292 rogid:NOmMW54DNa0o7vM945DlZgVUy44559292 intact-crc:C861C090F90BCB48|rigid:80YJvwepFKDrZxpxW+mTYcdZFbE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30605 uniprotkb:P50276 intact:EBI-2050956|uniprotkb:D6VTB9|ensemblfungi:YDR497C intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:itr1_yeast(display_long)|uniprotkb:D9719.3(orf name)|uniprotkb:YDR497C(locus name)|uniprotkb:ITR1(gene name)|psi-mi:ITR1(display_short) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321170|imex:IM-14275-661 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010785.1|sgd:S000002905|dip:DIP-7406N|mint:P30605|ensemblfungi:YDR497C(gene)|ensemblfungi:YDR497C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GgtK4YFe7ZCZcmVpV5q1KY2F0Ds559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:E87034116CC2047F|rigid:S8MDiazYxek/vGzBO4PVFOL+3WQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53278 uniprotkb:P30605 intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C intact:EBI-2050956|uniprotkb:D6VTB9|ensemblfungi:YDR497C psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name) psi-mi:itr1_yeast(display_long)|uniprotkb:D9719.3(orf name)|uniprotkb:YDR497C(locus name)|uniprotkb:ITR1(gene name)|psi-mi:ITR1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321181|imex:IM-14275-662 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome) refseq:NP_010785.1|sgd:S000002905|dip:DIP-7406N|mint:P30605|ensemblfungi:YDR497C(gene)|ensemblfungi:YDR497C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:D482327C9274C026 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292 rogid:GgtK4YFe7ZCZcmVpV5q1KY2F0Ds559292 intact-crc:34EFA4145444594C|rigid:idXXkBoETWK5lCSQaSkXycDNUmo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30605 uniprotkb:Q02785 intact:EBI-2050956|uniprotkb:D6VTB9|ensemblfungi:YDR497C intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:itr1_yeast(display_long)|uniprotkb:D9719.3(orf name)|uniprotkb:YDR497C(locus name)|uniprotkb:ITR1(gene name)|psi-mi:ITR1(display_short) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321192|imex:IM-14275-663 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010785.1|sgd:S000002905|dip:DIP-7406N|mint:P30605|ensemblfungi:YDR497C(gene)|ensemblfungi:YDR497C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GgtK4YFe7ZCZcmVpV5q1KY2F0Ds559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:8C72E05AE4A2E930|rigid:XsDaxKh98efDvd4PVEtI32/wqj8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:P30605 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-2050956|uniprotkb:D6VTB9|ensemblfungi:YDR497C psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:itr1_yeast(display_long)|uniprotkb:D9719.3(orf name)|uniprotkb:YDR497C(locus name)|uniprotkb:ITR1(gene name)|psi-mi:ITR1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321203|imex:IM-14275-664 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 refseq:NP_010785.1|sgd:S000002905|dip:DIP-7406N|mint:P30605|ensemblfungi:YDR497C(gene)|ensemblfungi:YDR497C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:GgtK4YFe7ZCZcmVpV5q1KY2F0Ds559292 intact-crc:C242E5774D12BE6D|rigid:jp62+/qHW96b9p5x4aVhwSPoGXc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30605 uniprotkb:Q08967 intact:EBI-2050956|uniprotkb:D6VTB9|ensemblfungi:YDR497C intact:EBI-36673|uniprotkb:D6W3E9|ensemblfungi:YPL221W psi-mi:itr1_yeast(display_long)|uniprotkb:D9719.3(orf name)|uniprotkb:YDR497C(locus name)|uniprotkb:ITR1(gene name)|psi-mi:ITR1(display_short) psi-mi:flc1_yeast(display_long)|uniprotkb:FAD transporter 1(gene name synonym)|uniprotkb:FLC1(gene name)|psi-mi:FLC1(display_short)|uniprotkb:TRP-like ion channel protein FLC1(gene name synonym)|uniprotkb:Heme utilization factor 1(gene name synonym)|uniprotkb:Bypass of PAM1 protein 1(gene name synonym)|uniprotkb:HUF1(gene name synonym)|uniprotkb:YPL221W(locus name)|uniprotkb:BOP1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321225|imex:IM-14275-666 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010785.1|sgd:S000002905|dip:DIP-7406N|mint:P30605|ensemblfungi:YDR497C(gene)|ensemblfungi:YDR497C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 refseq:NP_015103.1|sgd:S000006142|mint:Q08967|dip:DIP-3965N|ensemblfungi:YPL221W(gene)|ensemblfungi:YPL221W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055085"(transmembrane transport)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GgtK4YFe7ZCZcmVpV5q1KY2F0Ds559292 rogid:r6CcZGEjxHUk2w0iBUBvnAPaFd4559292 intact-crc:35D2CF0993134051|rigid:8SwN1cqtx3pg0lZOIms9ZVkaIoQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P30605 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-2050956|uniprotkb:D6VTB9|ensemblfungi:YDR497C psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:itr1_yeast(display_long)|uniprotkb:D9719.3(orf name)|uniprotkb:YDR497C(locus name)|uniprotkb:ITR1(gene name)|psi-mi:ITR1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321214|imex:IM-14275-665 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_010785.1|sgd:S000002905|dip:DIP-7406N|mint:P30605|ensemblfungi:YDR497C(gene)|ensemblfungi:YDR497C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:GgtK4YFe7ZCZcmVpV5q1KY2F0Ds559292 intact-crc:82591224AAEF8CF0|rigid:xWP+TDL5LLnYkEzw7JNxUDYn81Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12372 uniprotkb:P31374 intact:EBI-30098|uniprotkb:D6VXU8|ensemblfungi:YLL061W intact:EBI-9442|ensemblfungi:YAL017W|uniprotkb:D6VPK1 psi-mi:mmp1_yeast(display_long)|uniprotkb:MMP1(gene name)|psi-mi:MMP1(display_short)|uniprotkb:L0555(orf name)|uniprotkb:YLL061W(locus name) psi-mi:psk1_yeast(display_long)|uniprotkb:YAL017W(locus name)|uniprotkb:YAL002(orf name)|uniprotkb:FUN31(orf name)|uniprotkb:PSK1(gene name)|psi-mi:PSK1(display_short)|uniprotkb:PAS kinase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321236|imex:IM-14275-667 author score:99.34 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013039.1|sgd:S000003984|dip:DIP-8952N|mint:Q12372|ensemblfungi:YLL061W(gene)|ensemblfungi:YLL061W_mRNA(transcript)|go:"GO:0000100"(S-methylmethionine transmembrane transporter activity)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015806"(S-methylmethionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004841(Amino acid permease-associated region) ensemblfungi:YAL017W(gene)|ensemblfungi:YAL017W_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0060917"("regulation of (1->6)-beta-D-glucan biosynthetic process")|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000014(PAS)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR035965|refseq:NP_009385.2|sgd:S000000015|mint:P31374|dip:DIP-6267N psi-mi:"MI:0469"(intact) - crc64:9A2AF4A9C1785586 figure legend:tables S3 and S4|author-confidence:99.34|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:f3BzvHayrfhufemt+aCXKfCYr80559292 rogid:p8JyiNrDY8XWl8MvEHC71VXt8Rs559292 intact-crc:27193FC00FC539A9|rigid:1iMZI0iXm8GtJZryTae/EqDWYsE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31412 uniprotkb:P31383 intact:EBI-20260|uniprotkb:D6VXK7|ensemblfungi:YKL080W intact:EBI-1936|uniprotkb:D6VPK2|ensemblfungi:YAL016W psi-mi:vatc_yeast(display_long)|uniprotkb:VMA5(gene name)|psi-mi:VMA5(display_short)|uniprotkb:VAT3(gene name synonym)|uniprotkb:VATC(gene name synonym)|uniprotkb:YKL410(orf name)|uniprotkb:YKL080W(locus name)|uniprotkb:Vacuolar proton pump subunit C(gene name synonym)|uniprotkb:V-ATPase 42 kDa subunit(gene name synonym) psi-mi:2aaa_yeast(display_long)|uniprotkb:TPD3(gene name)|psi-mi:TPD3(display_short)|uniprotkb:YAL016W(locus name)|uniprotkb:FUN32(orf name)|uniprotkb:PR65(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321247|imex:IM-14275-668 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012843.1|sgd:S000001563|ensemblfungi:YKL080W(gene)|ensemblfungi:YKL080W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004907(ATPase, V1 complex, subunit C)|interpro:IPR036132|rcsb pdb:1U7L|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4DL0|rcsb pdb:4EFA|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-4701N|mint:P31412 refseq:NP_009386.1|sgd:S000000014|dip:DIP-2010N|mint:P31383|ensemblfungi:YAL016W(gene)|ensemblfungi:YAL016W_mRNA(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006417"(regulation of translation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043332"(mating projection tip)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-389513|reactome:R-SCE-6811558|reactome:R-SCE-69273|reactome:R-SCE-975957 psi-mi:"MI:0469"(intact) crc64:0CD1B814046C377E crc64:7ED350FB20633DC8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:NBI0upCB5yxAyMQgccBcLhjZk8s559292 rogid:ndyq0uJEmHu5uZbiW7T/GTM0GRg559292 intact-crc:9CC897E7C76E554D|rigid:nL8Gkha7HhTbHyb2PX222KuEyaw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37012 uniprotkb:P31383 intact:EBI-13296|uniprotkb:D6VZS7|ensemblfungi:YMR105C intact:EBI-1936|uniprotkb:D6VPK2|ensemblfungi:YAL016W psi-mi:pgm2_yeast(display_long)|uniprotkb:PGM2(gene name)|psi-mi:PGM2(display_short)|uniprotkb:GAL5(gene name synonym)|uniprotkb:YMR105C(locus name)|uniprotkb:YM9718.04C(orf name)|uniprotkb:Glucose phosphomutase 2(gene name synonym)|uniprotkb:"D-glucose-1,6-diphosphate:D-glucose-1-phosphate phosphotransferase"(gene name synonym)|uniprotkb:GA-5(gene name synonym) psi-mi:2aaa_yeast(display_long)|uniprotkb:TPD3(gene name)|psi-mi:TPD3(display_short)|uniprotkb:YAL016W(locus name)|uniprotkb:FUN32(orf name)|uniprotkb:PR65(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321258|imex:IM-14275-669 author score:99.26 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013823.1|sgd:S000004711|mint:P37012|dip:DIP-6499N|ensemblfungi:YMR105C(gene)|ensemblfungi:YMR105C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004614"(phosphoglucomutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019255"(glucose 1-phosphate metabolic process)|go:"GO:0019388"(galactose catabolic process)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR036900 refseq:NP_009386.1|sgd:S000000014|dip:DIP-2010N|mint:P31383|ensemblfungi:YAL016W(gene)|ensemblfungi:YAL016W_mRNA(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006417"(regulation of translation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043332"(mating projection tip)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-389513|reactome:R-SCE-6811558|reactome:R-SCE-69273|reactome:R-SCE-975957 psi-mi:"MI:0469"(intact) crc64:45B78AFF8197645E crc64:7ED350FB20633DC8 figure legend:tables S3 and S4|author-confidence:99.26|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miT4vpKTbsa/OfXIppW6h1+TbPs559292 rogid:ndyq0uJEmHu5uZbiW7T/GTM0GRg559292 intact-crc:F00BADA27DCC1640|rigid:vqyZpIyUhBtsGsEx4+fNU/ovs/c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40994 uniprotkb:P31383 intact:EBI-2824|uniprotkb:D6W2F5|ensemblfungi:YOR094W intact:EBI-1936|uniprotkb:D6VPK2|ensemblfungi:YAL016W psi-mi:arf3_yeast(display_long)|uniprotkb:ARF3(gene name)|psi-mi:ARF3(display_short)|uniprotkb:YOR3172W(orf name)|uniprotkb:YOR094W(locus name) psi-mi:2aaa_yeast(display_long)|uniprotkb:TPD3(gene name)|psi-mi:TPD3(display_short)|uniprotkb:YAL016W(locus name)|uniprotkb:FUN32(orf name)|uniprotkb:PR65(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321269|imex:IM-14275-670 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014737.1|sgd:S000005620|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P40994|interpro:IPR041838|ensemblfungi:YOR094W(gene)|ensemblfungi:YOR094W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010513"(positive regulation of phosphatidylinositol biosynthetic process)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0036267"(invasive filamentous growth)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization) refseq:NP_009386.1|sgd:S000000014|dip:DIP-2010N|mint:P31383|ensemblfungi:YAL016W(gene)|ensemblfungi:YAL016W_mRNA(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006417"(regulation of translation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043332"(mating projection tip)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-389513|reactome:R-SCE-6811558|reactome:R-SCE-69273|reactome:R-SCE-975957 psi-mi:"MI:0469"(intact) - crc64:7ED350FB20633DC8 figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:uC+fupPUZajD7m7pLEO/K0Kuudo559292 rogid:ndyq0uJEmHu5uZbiW7T/GTM0GRg559292 intact-crc:F50FB0067263B815|rigid:G2Ws1Yczct7+PHwmmuXSDX74P5c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31383 uniprotkb:Q12043 intact:EBI-1936|uniprotkb:D6VPK2|ensemblfungi:YAL016W intact:EBI-34845|uniprotkb:Q7LH13|uniprotkb:D6W2E4|ensemblfungi:YOR081C psi-mi:2aaa_yeast(display_long)|uniprotkb:TPD3(gene name)|psi-mi:TPD3(display_short)|uniprotkb:YAL016W(locus name)|uniprotkb:FUN32(orf name)|uniprotkb:PR65(gene name synonym) psi-mi:tgl5_yeast(display_long)|uniprotkb:TGL5(gene name)|psi-mi:TGL5(display_short)|uniprotkb:STC2(gene name synonym)|uniprotkb:YOR29-32(orf name)|uniprotkb:YOR2964C(orf name)|uniprotkb:YOR081C(locus name)|uniprotkb:Lipase 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321280|imex:IM-14275-671 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009386.1|sgd:S000000014|dip:DIP-2010N|mint:P31383|ensemblfungi:YAL016W(gene)|ensemblfungi:YAL016W_mRNA(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006417"(regulation of translation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043332"(mating projection tip)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-389513|reactome:R-SCE-6811558|reactome:R-SCE-69273|reactome:R-SCE-975957 refseq:NP_014724.1|sgd:S000005607|mint:Q12043|dip:DIP-6280N|ensemblfungi:YOR081C(gene)|ensemblfungi:YOR081C_mRNA(transcript)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042171"(lysophosphatidic acid acyltransferase activity)|interpro:IPR002641(Patatin)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR021771 psi-mi:"MI:0469"(intact) crc64:7ED350FB20633DC8 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ndyq0uJEmHu5uZbiW7T/GTM0GRg559292 rogid:ccHxygbWfyyQXKaSbOL4iYhikms559292 intact-crc:0A9ADDFF55807CC6|rigid:BOKEcCOvH7w5lXn8Ls2w86/ttZk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25655 uniprotkb:P31384 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321302|imex:IM-14275-673 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C psi-mi:"MI:0469"(intact) crc64:5B2AE15BCF95E009 crc64:5CDB2E8FEDDBEF6F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292 intact-crc:F9721E06FE625381|rigid:CPQrrjEMrQF2HZ7Po+PThq1dAbE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31384 uniprotkb:P06102 intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C intact:EBI-12165|uniprotkb:D6VVP4|uniprotkb:Q6B233|ensemblfungi:YIL038C psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name) psi-mi:not3_yeast(display_long)|uniprotkb:NOT3(gene name)|psi-mi:NOT3(display_short)|uniprotkb:YIL038C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321291|imex:IM-14275-672 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR038635|interpro:IPR040168|ensemblfungi:YIL038C(gene)|ensemblfungi:YIL038C_mRNA(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|refseq:NP_012226.3|sgd:S000001300|dip:DIP-2256N|mint:P06102 psi-mi:"MI:0469"(intact) crc64:5CDB2E8FEDDBEF6F crc64:69B76694FCC6846F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292 rogid:EfakZPDNU3FZeI5+rnu7YV1UsCg559292 intact-crc:BD63F56418593A14|rigid:xASG8/99VIyMgjm/VsRTdH4C6eI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34909 uniprotkb:P31384 intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321313|imex:IM-14275-674 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C psi-mi:"MI:0469"(intact) crc64:8847084BD9BF48B7 crc64:5CDB2E8FEDDBEF6F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292 intact-crc:8E48A21CB1315BB2|rigid:zSAYSbnnbgqaqF2NWxxddwVpxUE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31384 uniprotkb:P53829 intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name) psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321324|imex:IM-14275-675 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 psi-mi:"MI:0469"(intact) crc64:5CDB2E8FEDDBEF6F crc64:F3DBABE6AD3C7F3C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 intact-crc:09FBBACA18FB5ED7|rigid:q0Bq/F5DAYqdA1/DvqdoRWM5QYA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31384 uniprotkb:P57743 intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C intact:EBI-10227|uniprotkb:Q05176|uniprotkb:Q06759|uniprotkb:D6VZ73|ensemblfungi:YLR438C-A psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name) psi-mi:lsm3_yeast(display_long)|uniprotkb:LSM3(gene name)|psi-mi:LSM3(display_short)|uniprotkb:SMX4(gene name synonym)|uniprotkb:USS2(gene name synonym)|uniprotkb:YLR438C-A(locus name)|uniprotkb:SmX4 protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321335|imex:IM-14275-676 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C sgd:S000006434|ensemblfungi:YLR438C-A(gene)|ensemblfungi:YLR438C-A_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034105|interpro:IPR040002|rcsb pdb:3BW1|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:4N0A|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039|rcsb pdb:4M75|refseq:NP_013543.3|dip:DIP-2587N|mint:P57743 psi-mi:"MI:0469"(intact) crc64:5CDB2E8FEDDBEF6F crc64:787084EF6A5945B7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292 rogid:nYl7At1SnlSwN+nWr1F1xm0tdDE559292 intact-crc:04414514248267E4|rigid:79dh+XPs8vx0BmpEF2FWZJ7vKLQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08446 uniprotkb:P31384 intact:EBI-17070|ensemblfungi:YOR057W|uniprotkb:D6W2C0|uniprotkb:E9P8U7 intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C psi-mi:sgt1_yeast(display_long)|uniprotkb:SGT1(gene name)|psi-mi:SGT1(display_short)|uniprotkb:YOR057W(locus name)|uniprotkb:YOR29-08(orf name)|uniprotkb:Suppressor of G2 allele of SKP1(gene name synonym) psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321346|imex:IM-14275-677 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014700.1|sgd:S000005583|ensemblfungi:YOR057W(gene)|ensemblfungi:YOR057W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0007049"(cell cycle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034622"|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044563|rcsb pdb:5AN3|reactome:R-SCE-844456|dip:DIP-1628N|mint:Q08446 refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C psi-mi:"MI:0469"(intact) crc64:5DE65874BE155552 crc64:5CDB2E8FEDDBEF6F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:DJ37U8QHPE7Wi/+kOiEwCg1mxCw559292 rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292 intact-crc:22E913A91CA7739C|rigid:vtFrm81n68TS7llSxLFgKeXZ1e4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12514 uniprotkb:P31384 intact:EBI-12184|uniprotkb:D6W476|ensemblfungi:YPR072W intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C psi-mi:not5_yeast(display_long)|uniprotkb:NOT5(gene name)|psi-mi:NOT5(display_short)|uniprotkb:YP9499.27(orf name)|uniprotkb:YPR072W(locus name) psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321357|imex:IM-14275-678 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPR072W(gene)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|rcsb pdb:6TB3|ensemblfungi:YPR072W_mRNA(transcript)|refseq:NP_015397.1|sgd:S000006276|dip:DIP-2257N|mint:Q12514 refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C psi-mi:"MI:0469"(intact) crc64:073137119B3E92BC crc64:5CDB2E8FEDDBEF6F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+XON8Ps4xCFhw058U9d2voUy2dc559292 rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292 intact-crc:85809068072DB9A4|rigid:oSq6NPZB2j8WD13CDxTUS45Z5ns false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31787 uniprotkb:P32610 intact:EBI-2060|uniprotkb:Q45U46|uniprotkb:D6VUH4|ensemblfungi:YGR037C intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W psi-mi:acbp_yeast(display_long)|uniprotkb:ACB1(gene name)|psi-mi:ACB1(display_short)|uniprotkb:ACB(gene name synonym)|uniprotkb:YGR037C(locus name) psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321368|imex:IM-14275-679 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR035984|sgd:S000003269|interpro:IPR022408|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|refseq:NP_011551.3|mint:P31787|ensemblfungi:YGR037C(gene)|ensemblfungi:YGR037C_mRNA(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008289"(lipid binding)|go:"GO:0036042"(long-chain fatty acyl-CoA binding)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|rcsb pdb:1ST7|reactome:R-SCE-390247|reactome:R-SCE-77289|reactome:R-SCE-9033241 refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610 psi-mi:"MI:0469"(intact) - crc64:FDE93E1FAF0AEC5B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:xsK42ArJkY/c6YimJ0v2cXZRWrY559292 rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292 intact-crc:A264492BA4235C8C|rigid:1/5Uw/b++AqHoQyQvt9d2HmjMeE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38009 uniprotkb:P31787 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 intact:EBI-2060|uniprotkb:Q45U46|uniprotkb:D6VUH4|ensemblfungi:YGR037C psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:acbp_yeast(display_long)|uniprotkb:ACB1(gene name)|psi-mi:ACB1(display_short)|uniprotkb:ACB(gene name synonym)|uniprotkb:YGR037C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321379|imex:IM-14275-680 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N interpro:IPR035984|sgd:S000003269|interpro:IPR022408|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|refseq:NP_011551.3|mint:P31787|ensemblfungi:YGR037C(gene)|ensemblfungi:YGR037C_mRNA(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008289"(lipid binding)|go:"GO:0036042"(long-chain fatty acyl-CoA binding)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|rcsb pdb:1ST7|reactome:R-SCE-390247|reactome:R-SCE-77289|reactome:R-SCE-9033241 psi-mi:"MI:0469"(intact) crc64:8ABA71761B512242 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 rogid:xsK42ArJkY/c6YimJ0v2cXZRWrY559292 intact-crc:70294BE308CBA57C|rigid:GLUc80Ko+dLyGo9YomPf8dY7kdk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39111 uniprotkb:P31787 intact:EBI-20272|uniprotkb:D6VUF5|ensemblfungi:YGR020C intact:EBI-2060|uniprotkb:Q45U46|uniprotkb:D6VUH4|ensemblfungi:YGR037C psi-mi:vatf_yeast(display_long)|uniprotkb:VMA7(gene name)|psi-mi:VMA7(display_short)|uniprotkb:YGR020C(locus name)|uniprotkb:Vacuolar proton pump subunit F(gene name synonym)|uniprotkb:V-ATPase 14 kDa subunit(gene name synonym) psi-mi:acbp_yeast(display_long)|uniprotkb:ACB1(gene name)|psi-mi:ACB1(display_short)|uniprotkb:ACB(gene name synonym)|uniprotkb:YGR037C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321401|imex:IM-14275-682 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011534.1|sgd:S000003252|ensemblfungi:YGR020C(gene)|ensemblfungi:YGR020C_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016020"(membrane)|go:"GO:0042625"(ATPase-coupled ion transmembrane transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005772(ATPase, V1 complex, subunit F, eukaryotic)|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|interpro:IPR036906|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4IX9|rcsb pdb:4RND|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2077N|mint:P39111 interpro:IPR035984|sgd:S000003269|interpro:IPR022408|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|refseq:NP_011551.3|mint:P31787|ensemblfungi:YGR037C(gene)|ensemblfungi:YGR037C_mRNA(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008289"(lipid binding)|go:"GO:0036042"(long-chain fatty acyl-CoA binding)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|rcsb pdb:1ST7|reactome:R-SCE-390247|reactome:R-SCE-77289|reactome:R-SCE-9033241 psi-mi:"MI:0469"(intact) crc64:D21EC0980EB99DFF - figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VtthQl2jj9fpjv3psX0YUNbIAKU559292 rogid:xsK42ArJkY/c6YimJ0v2cXZRWrY559292 intact-crc:0C56624FBB41A054|rigid:cwHRRVnUMJi9bWBanVpXsajIxC0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38328 uniprotkb:P31787 intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C intact:EBI-2060|uniprotkb:Q45U46|uniprotkb:D6VUH4|ensemblfungi:YGR037C psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:acbp_yeast(display_long)|uniprotkb:ACB1(gene name)|psi-mi:ACB1(display_short)|uniprotkb:ACB(gene name synonym)|uniprotkb:YGR037C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321390|imex:IM-14275-681 author score:99.26 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 interpro:IPR035984|sgd:S000003269|interpro:IPR022408|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|refseq:NP_011551.3|mint:P31787|ensemblfungi:YGR037C(gene)|ensemblfungi:YGR037C_mRNA(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008289"(lipid binding)|go:"GO:0036042"(long-chain fatty acyl-CoA binding)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|rcsb pdb:1ST7|reactome:R-SCE-390247|reactome:R-SCE-77289|reactome:R-SCE-9033241 psi-mi:"MI:0469"(intact) crc64:D75C6BB8EC35EEDF - figure legend:tables S3 and S4|author-confidence:99.26|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 rogid:xsK42ArJkY/c6YimJ0v2cXZRWrY559292 intact-crc:8CD971787C1E7D88|rigid:fGGWgNUnhqDSOkwdZe1UGwxV+ys false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41810 uniprotkb:P31787 intact:EBI-4869|uniprotkb:Q03779|uniprotkb:D6VSL9|ensemblfungi:YDR238C intact:EBI-2060|uniprotkb:Q45U46|uniprotkb:D6VUH4|ensemblfungi:YGR037C psi-mi:copb_yeast(display_long)|uniprotkb:SEC26(gene name)|psi-mi:SEC26(display_short)|uniprotkb:YDR238C(locus name)|uniprotkb:YD8419.05C(orf name)|uniprotkb:Beta-coat protein(gene name synonym) psi-mi:acbp_yeast(display_long)|uniprotkb:ACB1(gene name)|psi-mi:ACB1(display_short)|uniprotkb:ACB(gene name synonym)|uniprotkb:YGR037C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321412|imex:IM-14275-683 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002646|refseq:NP_010524.3|dip:DIP-6467N|mint:P41810|ensemblfungi:YDR238C(gene)|ensemblfungi:YDR238C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|reactome:R-SCE-6798695|reactome:R-SCE-6807878|reactome:R-SCE-6811434 interpro:IPR035984|sgd:S000003269|interpro:IPR022408|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|refseq:NP_011551.3|mint:P31787|ensemblfungi:YGR037C(gene)|ensemblfungi:YGR037C_mRNA(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008289"(lipid binding)|go:"GO:0036042"(long-chain fatty acyl-CoA binding)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|rcsb pdb:1ST7|reactome:R-SCE-390247|reactome:R-SCE-77289|reactome:R-SCE-9033241 psi-mi:"MI:0469"(intact) crc64:885420DB026BCFA3 - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZfLp1BUmvVuTiXn7/Zbf/3m6VtE559292 rogid:xsK42ArJkY/c6YimJ0v2cXZRWrY559292 intact-crc:0E45DE339344F48B|rigid:KLrtY/+DtCexroT/rVGyeLEsFtg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41811 uniprotkb:P31787 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W intact:EBI-2060|uniprotkb:Q45U46|uniprotkb:D6VUH4|ensemblfungi:YGR037C psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:acbp_yeast(display_long)|uniprotkb:ACB1(gene name)|psi-mi:ACB1(display_short)|uniprotkb:ACB(gene name synonym)|uniprotkb:YGR037C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321423|imex:IM-14275-684 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 interpro:IPR035984|sgd:S000003269|interpro:IPR022408|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|refseq:NP_011551.3|mint:P31787|ensemblfungi:YGR037C(gene)|ensemblfungi:YGR037C_mRNA(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008289"(lipid binding)|go:"GO:0036042"(long-chain fatty acyl-CoA binding)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|rcsb pdb:1ST7|reactome:R-SCE-390247|reactome:R-SCE-77289|reactome:R-SCE-9033241 psi-mi:"MI:0469"(intact) crc64:6A5E50BBEB02CB58 - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 rogid:xsK42ArJkY/c6YimJ0v2cXZRWrY559292 intact-crc:91FCD515B6B0AADF|rigid:2D1wB8cti2p+aDAURg9RcPtj9pc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31787 uniprotkb:P54783 intact:EBI-2060|uniprotkb:Q45U46|uniprotkb:D6VUH4|ensemblfungi:YGR037C intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:acbp_yeast(display_long)|uniprotkb:ACB1(gene name)|psi-mi:ACB1(display_short)|uniprotkb:ACB(gene name synonym)|uniprotkb:YGR037C(locus name) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321434|imex:IM-14275-685 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR035984|sgd:S000003269|interpro:IPR022408|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|refseq:NP_011551.3|mint:P31787|ensemblfungi:YGR037C(gene)|ensemblfungi:YGR037C_mRNA(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008289"(lipid binding)|go:"GO:0036042"(long-chain fatty acyl-CoA binding)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|rcsb pdb:1ST7|reactome:R-SCE-390247|reactome:R-SCE-77289|reactome:R-SCE-9033241 go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:xsK42ArJkY/c6YimJ0v2cXZRWrY559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:D3BE1C5C81BF2321|rigid:Z2I0bk2RME5Hpmlu1+hSQdfaD0A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31787 uniprotkb:Q6Q5K6 intact:EBI-2060|uniprotkb:Q45U46|uniprotkb:D6VUH4|ensemblfungi:YGR037C intact:EBI-392766|ensemblfungi:YML058W-A|uniprotkb:D6VZB5 psi-mi:acbp_yeast(display_long)|uniprotkb:ACB1(gene name)|psi-mi:ACB1(display_short)|uniprotkb:ACB(gene name synonym)|uniprotkb:YGR037C(locus name) psi-mi:hug1_yeast(display_long)|uniprotkb:HUG1(gene name)|psi-mi:HUG1(display_short)|uniprotkb:YML058W-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321445|imex:IM-14275-686 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR035984|sgd:S000003269|interpro:IPR022408|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|refseq:NP_011551.3|mint:P31787|ensemblfungi:YGR037C(gene)|ensemblfungi:YGR037C_mRNA(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008289"(lipid binding)|go:"GO:0036042"(long-chain fatty acyl-CoA binding)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|rcsb pdb:1ST7|reactome:R-SCE-390247|reactome:R-SCE-77289|reactome:R-SCE-9033241 ensemblfungi:YML058W-A(gene)|ensemblfungi:YML058W-A_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:1905117"(regulation of ribonucleoside-diphosphate reductase activity)|go:"GO:1990846"(ribonucleoside-diphosphate reductase inhibitor activity)|sgd:S000007472|refseq:NP_219498.1|mint:Q6Q5K6 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:xsK42ArJkY/c6YimJ0v2cXZRWrY559292 rogid:x+quBrnP+8yql7JGQ1NK4j5ubbw559292 intact-crc:8283F2A50AE092F2|rigid:ZQ1r8VhR8qApK+Y9AFYUVG4DqqI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32263 uniprotkb:P32263 intact:EBI-13885|uniprotkb:D3DLS2|ensemblfungi:YER023W intact:EBI-13885|uniprotkb:D3DLS2|ensemblfungi:YER023W psi-mi:p5cr_yeast(display_long)|uniprotkb:PRO3(gene name)|psi-mi:PRO3(display_short)|uniprotkb:ORE2(gene name synonym)|uniprotkb:YER023W(locus name) psi-mi:p5cr_yeast(display_long)|uniprotkb:PRO3(gene name)|psi-mi:PRO3(display_short)|uniprotkb:ORE2(gene name synonym)|uniprotkb:YER023W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321456|imex:IM-14275-687 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000825|ensemblfungi:YER023W(gene)|ensemblfungi:YER023W_mRNA(transcript)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR028939|interpro:IPR029036|interpro:IPR036291|reactome:R-SCE-8964539|refseq:NP_010940.3|mint:P32263|dip:DIP-1529N sgd:S000000825|ensemblfungi:YER023W(gene)|ensemblfungi:YER023W_mRNA(transcript)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR028939|interpro:IPR029036|interpro:IPR036291|reactome:R-SCE-8964539|refseq:NP_010940.3|mint:P32263|dip:DIP-1529N psi-mi:"MI:0469"(intact) crc64:AEB71D93B46D08B3 crc64:AEB71D93B46D08B3 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R3ywXuxBQ38HK2xghtFdCvHJ9vc559292 rogid:R3ywXuxBQ38HK2xghtFdCvHJ9vc559292 intact-crc:966BD125DFCA19F8|rigid:XWjaFUr3Vjfwx8iH9gSGNw1qFLw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32263 uniprotkb:P38636 intact:EBI-13885|uniprotkb:D3DLS2|ensemblfungi:YER023W intact:EBI-2046026|uniprotkb:D6W0T4|uniprotkb:E9P8W0|ensemblfungi:YNL259C psi-mi:p5cr_yeast(display_long)|uniprotkb:PRO3(gene name)|psi-mi:PRO3(display_short)|uniprotkb:ORE2(gene name synonym)|uniprotkb:YER023W(locus name) psi-mi:atx1_yeast(display_long)|uniprotkb:N0840(orf name)|uniprotkb:YNL259C(locus name)|uniprotkb:ATX1(gene name)|psi-mi:ATX1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321467|imex:IM-14275-688 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000825|ensemblfungi:YER023W(gene)|ensemblfungi:YER023W_mRNA(transcript)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR028939|interpro:IPR029036|interpro:IPR036291|reactome:R-SCE-8964539|refseq:NP_010940.3|mint:P32263|dip:DIP-1529N refseq:NP_014140.1|sgd:S000005203|dip:DIP-813N|mint:P38636|ensemblfungi:YNL259C(gene)|ensemblfungi:YNL259C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006825"(copper ion transport)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|interpro:IPR006121(Heavy metal transport/detoxification protein)|interpro:IPR017969|interpro:IPR036163|rcsb pdb:1CC7|rcsb pdb:1CC8|rcsb pdb:1FD8|rcsb pdb:1FES|rcsb pdb:1UV1|rcsb pdb:1UV2|rcsb pdb:2GGP|rcsb pdb:3K7R|rcsb pdb:5VDE|rcsb pdb:5VDF psi-mi:"MI:0469"(intact) crc64:AEB71D93B46D08B3 crc64:9BDF0B542F80EA83 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R3ywXuxBQ38HK2xghtFdCvHJ9vc559292 rogid:18VKJsTH1VyY1vod4zaFwJYPd+A559292 intact-crc:8CD6FD1A458AF16D|rigid:xZsRt/CxzxRUivJyfbcJvNq1+CU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32264 uniprotkb:P32264 intact:EBI-13879|ensemblfungi:YDR300C|uniprotkb:D6VSS9 intact:EBI-13879|ensemblfungi:YDR300C|uniprotkb:D6VSS9 psi-mi:prob_yeast(display_long)|uniprotkb:PRO1(gene name)|psi-mi:PRO1(display_short)|uniprotkb:YDR300C(locus name)|uniprotkb:D9740.12(orf name)|uniprotkb:Gamma-glutamyl kinase(gene name synonym) psi-mi:prob_yeast(display_long)|uniprotkb:PRO1(gene name)|psi-mi:PRO1(display_short)|uniprotkb:YDR300C(locus name)|uniprotkb:D9740.12(orf name)|uniprotkb:Gamma-glutamyl kinase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321489|imex:IM-14275-690 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002708|ensemblfungi:YDR300C(gene)|ensemblfungi:YDR300C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0034517"(ribophagy)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|interpro:IPR001057(Glutamate 5-kinase)|interpro:IPR002478(PUA)|interpro:IPR005715(Glutamate 5-kinase, ProB-related)|interpro:IPR011529(Glutamate 5-kinase, pro-B)|interpro:IPR015947(PUA-like)|interpro:IPR019797|interpro:IPR036393|interpro:IPR036974|interpro:IPR041739|go:"GO:0004349"(glutamate 5-kinase activity)|refseq:NP_010586.3|mint:P32264|dip:DIP-5221N sgd:S000002708|ensemblfungi:YDR300C(gene)|ensemblfungi:YDR300C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0034517"(ribophagy)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|interpro:IPR001057(Glutamate 5-kinase)|interpro:IPR002478(PUA)|interpro:IPR005715(Glutamate 5-kinase, ProB-related)|interpro:IPR011529(Glutamate 5-kinase, pro-B)|interpro:IPR015947(PUA-like)|interpro:IPR019797|interpro:IPR036393|interpro:IPR036974|interpro:IPR041739|go:"GO:0004349"(glutamate 5-kinase activity)|refseq:NP_010586.3|mint:P32264|dip:DIP-5221N psi-mi:"MI:0469"(intact) crc64:0DBAC7CA98051C80 crc64:0DBAC7CA98051C80 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9G1FUhbdFZQHcYx1kB0r3VPKICc559292 rogid:9G1FUhbdFZQHcYx1kB0r3VPKICc559292 intact-crc:2F44E0C8146B4B98|rigid:lyZ5zeK/uKlR0a6g0RHYNsJwrnM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41811 uniprotkb:P32263 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W intact:EBI-13885|uniprotkb:D3DLS2|ensemblfungi:YER023W psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:p5cr_yeast(display_long)|uniprotkb:PRO3(gene name)|psi-mi:PRO3(display_short)|uniprotkb:ORE2(gene name synonym)|uniprotkb:YER023W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321478|imex:IM-14275-689 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 sgd:S000000825|ensemblfungi:YER023W(gene)|ensemblfungi:YER023W_mRNA(transcript)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR028939|interpro:IPR029036|interpro:IPR036291|reactome:R-SCE-8964539|refseq:NP_010940.3|mint:P32263|dip:DIP-1529N psi-mi:"MI:0469"(intact) crc64:6A5E50BBEB02CB58 crc64:AEB71D93B46D08B3 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 rogid:R3ywXuxBQ38HK2xghtFdCvHJ9vc559292 intact-crc:1EE065B47C94571C|rigid:/o+aZ6fuUj4vRKhkOFtueJlm3e0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:P32319 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-13123|uniprotkb:D6VPY3|ensemblfungi:YBL017C psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:vps10_yeast(display_long)|uniprotkb:PEP1(gene name)|psi-mi:PEP1(display_short)|uniprotkb:Vacuolar carboxypeptidase sorting receptor VPS10(gene name synonym)|uniprotkb:Carboxypeptidase Y receptor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 1(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 1(gene name synonym)|uniprotkb:Sortilin VPS10(gene name synonym)|uniprotkb:VPS10(gene name synonym)|uniprotkb:VPT1(gene name synonym)|uniprotkb:YBL03.22(orf name)|uniprotkb:YBL0302(orf name)|uniprotkb:YBL017C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321500|imex:IM-14275-691 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 refseq:NP_009536.1|sgd:S000000113|mint:P32319|dip:DIP-5900N|ensemblfungi:YBL017C(gene)|ensemblfungi:YBL017C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000423"(mitophagy)|go:"GO:0000425"(pexophagy)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048203"(vesicle targeting, trans-Golgi to endosome)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR036278 psi-mi:"MI:0469"(intact) - crc64:C778A0400612ECF4 figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:dYYsekAaDw4SzmEUSe5tYb5a43M559292 intact-crc:60D3AA1F2A5F1877|rigid:d8RpvqhxyqRvPiWgeFIBgiIb9ro false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22137 uniprotkb:P32319 intact:EBI-4766|uniprotkb:D6VTU9|ensemblfungi:YGL206C intact:EBI-13123|uniprotkb:D6VPY3|ensemblfungi:YBL017C psi-mi:clh_yeast(display_long)|uniprotkb:CHC1(gene name)|psi-mi:CHC1(display_short)|uniprotkb:YGL206C(locus name) psi-mi:vps10_yeast(display_long)|uniprotkb:PEP1(gene name)|psi-mi:PEP1(display_short)|uniprotkb:Vacuolar carboxypeptidase sorting receptor VPS10(gene name synonym)|uniprotkb:Carboxypeptidase Y receptor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 1(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 1(gene name synonym)|uniprotkb:Sortilin VPS10(gene name synonym)|uniprotkb:VPS10(gene name synonym)|uniprotkb:VPT1(gene name synonym)|uniprotkb:YBL03.22(orf name)|uniprotkb:YBL0302(orf name)|uniprotkb:YBL017C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321511|imex:IM-14275-692 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011309.1|sgd:S000003174|dip:DIP-2279N|mint:P22137|ensemblfungi:YGL206C(gene)|ensemblfungi:YGL206C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0071439"(clathrin complex)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-432720|reactome:R-SCE-437239|reactome:R-SCE-8856828|reactome:R-SCE-8866427|reactome:R-SCE-8964038 refseq:NP_009536.1|sgd:S000000113|mint:P32319|dip:DIP-5900N|ensemblfungi:YBL017C(gene)|ensemblfungi:YBL017C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000423"(mitophagy)|go:"GO:0000425"(pexophagy)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048203"(vesicle targeting, trans-Golgi to endosome)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR036278 psi-mi:"MI:0469"(intact) crc64:622F3083DF2FE315 crc64:C778A0400612ECF4 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SAN6H3nVFozXZyTiRLaljMcIKIA559292 rogid:dYYsekAaDw4SzmEUSe5tYb5a43M559292 intact-crc:96B64915DE91B268|rigid:+S2qeGYc+nLHE6qRgbytzSjLqk4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32319 uniprotkb:P32319 intact:EBI-13123|uniprotkb:D6VPY3|ensemblfungi:YBL017C intact:EBI-13123|uniprotkb:D6VPY3|ensemblfungi:YBL017C psi-mi:vps10_yeast(display_long)|uniprotkb:PEP1(gene name)|psi-mi:PEP1(display_short)|uniprotkb:Vacuolar carboxypeptidase sorting receptor VPS10(gene name synonym)|uniprotkb:Carboxypeptidase Y receptor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 1(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 1(gene name synonym)|uniprotkb:Sortilin VPS10(gene name synonym)|uniprotkb:VPS10(gene name synonym)|uniprotkb:VPT1(gene name synonym)|uniprotkb:YBL03.22(orf name)|uniprotkb:YBL0302(orf name)|uniprotkb:YBL017C(locus name) psi-mi:vps10_yeast(display_long)|uniprotkb:PEP1(gene name)|psi-mi:PEP1(display_short)|uniprotkb:Vacuolar carboxypeptidase sorting receptor VPS10(gene name synonym)|uniprotkb:Carboxypeptidase Y receptor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 1(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 1(gene name synonym)|uniprotkb:Sortilin VPS10(gene name synonym)|uniprotkb:VPS10(gene name synonym)|uniprotkb:VPT1(gene name synonym)|uniprotkb:YBL03.22(orf name)|uniprotkb:YBL0302(orf name)|uniprotkb:YBL017C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321522|imex:IM-14275-693 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009536.1|sgd:S000000113|mint:P32319|dip:DIP-5900N|ensemblfungi:YBL017C(gene)|ensemblfungi:YBL017C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000423"(mitophagy)|go:"GO:0000425"(pexophagy)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048203"(vesicle targeting, trans-Golgi to endosome)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR036278 refseq:NP_009536.1|sgd:S000000113|mint:P32319|dip:DIP-5900N|ensemblfungi:YBL017C(gene)|ensemblfungi:YBL017C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000423"(mitophagy)|go:"GO:0000425"(pexophagy)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048203"(vesicle targeting, trans-Golgi to endosome)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR036278 psi-mi:"MI:0469"(intact) crc64:C778A0400612ECF4 crc64:C778A0400612ECF4 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dYYsekAaDw4SzmEUSe5tYb5a43M559292 rogid:dYYsekAaDw4SzmEUSe5tYb5a43M559292 intact-crc:15D68FFCCC569CBD|rigid:I4IQpQx8YXj9pcD1Pq0CVUeDV7g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34110 uniprotkb:P32319 intact:EBI-20415|uniprotkb:D6VW33|ensemblfungi:YJL154C intact:EBI-13123|uniprotkb:D6VPY3|ensemblfungi:YBL017C psi-mi:vps35_yeast(display_long)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:Vacuolar protein-targeting protein 7(gene name synonym)|uniprotkb:VPT7(gene name synonym)|uniprotkb:J0580(orf name)|uniprotkb:YJL154C(locus name) psi-mi:vps10_yeast(display_long)|uniprotkb:PEP1(gene name)|psi-mi:PEP1(display_short)|uniprotkb:Vacuolar carboxypeptidase sorting receptor VPS10(gene name synonym)|uniprotkb:Carboxypeptidase Y receptor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 1(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 1(gene name synonym)|uniprotkb:Sortilin VPS10(gene name synonym)|uniprotkb:VPS10(gene name synonym)|uniprotkb:VPT1(gene name synonym)|uniprotkb:YBL03.22(orf name)|uniprotkb:YBL0302(orf name)|uniprotkb:YBL017C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321533|imex:IM-14275-694 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012381.1|sgd:S000003690|ensemblfungi:YJL154C(gene)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1904377"(positive regulation of protein localization to cell periphery)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR042491|reactome:R-SCE-3238698|ensemblfungi:YJL154C_mRNA(transcript)|dip:DIP-1743N|mint:P34110 refseq:NP_009536.1|sgd:S000000113|mint:P32319|dip:DIP-5900N|ensemblfungi:YBL017C(gene)|ensemblfungi:YBL017C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000423"(mitophagy)|go:"GO:0000425"(pexophagy)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048203"(vesicle targeting, trans-Golgi to endosome)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR036278 psi-mi:"MI:0469"(intact) crc64:DE1BC57B9DFB606E crc64:C778A0400612ECF4 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5KBi/lSF+BsMyg9ulP9eLCp2xCc559292 rogid:dYYsekAaDw4SzmEUSe5tYb5a43M559292 intact-crc:B88685584676AF7A|rigid:bZu22rFnzQFmEIGsFbe5AVLYp2U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38817 uniprotkb:P32319 intact:EBI-7569|uniprotkb:D3DL58|ensemblfungi:YHR108W intact:EBI-13123|uniprotkb:D6VPY3|ensemblfungi:YBL017C psi-mi:gga2_yeast(display_long)|uniprotkb:YHR108W(locus name)|uniprotkb:GGA2(gene name)|psi-mi:GGA2(display_short)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 2(gene name synonym) psi-mi:vps10_yeast(display_long)|uniprotkb:PEP1(gene name)|psi-mi:PEP1(display_short)|uniprotkb:Vacuolar carboxypeptidase sorting receptor VPS10(gene name synonym)|uniprotkb:Carboxypeptidase Y receptor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 1(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 1(gene name synonym)|uniprotkb:Sortilin VPS10(gene name synonym)|uniprotkb:VPS10(gene name synonym)|uniprotkb:VPT1(gene name synonym)|uniprotkb:YBL03.22(orf name)|uniprotkb:YBL0302(orf name)|uniprotkb:YBL017C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321544|imex:IM-14275-695 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011976.1|sgd:S000001150|mint:P38817|dip:DIP-2971N|ensemblfungi:YHR108W(gene)|ensemblfungi:YHR108W_mRNA(transcript)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|rcsb pdb:3MNM refseq:NP_009536.1|sgd:S000000113|mint:P32319|dip:DIP-5900N|ensemblfungi:YBL017C(gene)|ensemblfungi:YBL017C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000423"(mitophagy)|go:"GO:0000425"(pexophagy)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048203"(vesicle targeting, trans-Golgi to endosome)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR036278 psi-mi:"MI:0469"(intact) crc64:7AC3A317AEE302E2 crc64:C778A0400612ECF4 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:stplLxS8A9T/NqdjQXRVJTxnRsI559292 rogid:dYYsekAaDw4SzmEUSe5tYb5a43M559292 intact-crc:A075DB88C1D9973A|rigid:Z4HIgYHIaJXNt0GY6y+5J6ayY+k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32319 uniprotkb:P40335 intact:EBI-13123|uniprotkb:D6VPY3|ensemblfungi:YBL017C intact:EBI-20373|uniprotkb:D6VWC9|intact:EBI-3674163|uniprotkb:E9P910|ensemblfungi:YJL053W psi-mi:vps10_yeast(display_long)|uniprotkb:PEP1(gene name)|psi-mi:PEP1(display_short)|uniprotkb:Vacuolar carboxypeptidase sorting receptor VPS10(gene name synonym)|uniprotkb:Carboxypeptidase Y receptor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 1(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 1(gene name synonym)|uniprotkb:Sortilin VPS10(gene name synonym)|uniprotkb:VPS10(gene name synonym)|uniprotkb:VPT1(gene name synonym)|uniprotkb:YBL03.22(orf name)|uniprotkb:YBL0302(orf name)|uniprotkb:YBL017C(locus name) psi-mi:pep8_yeast(display_long)|uniprotkb:PEP8(gene name)|psi-mi:PEP8(display_short)|uniprotkb:GRD6(gene name synonym)|uniprotkb:VPS26(gene name synonym)|uniprotkb:VPT4(gene name synonym)|uniprotkb:J1152(orf name)|uniprotkb:YJL053W(locus name)|uniprotkb:Vacuolar protein-targeting protein 4(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 26(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321555|imex:IM-14275-696 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009536.1|sgd:S000000113|mint:P32319|dip:DIP-5900N|ensemblfungi:YBL017C(gene)|ensemblfungi:YBL017C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000423"(mitophagy)|go:"GO:0000425"(pexophagy)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048203"(vesicle targeting, trans-Golgi to endosome)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR036278 refseq:NP_012482.1|sgd:S000003589|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0140318"(protein transporter activity)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR028934|reactome:R-SCE-3238698|ensemblfungi:YJL053W(gene)|ensemblfungi:YJL053W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|dip:DIP-4572N|mint:P40335 psi-mi:"MI:0469"(intact) crc64:C778A0400612ECF4 crc64:40D15594E70A9B58 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dYYsekAaDw4SzmEUSe5tYb5a43M559292 rogid:mwZb20cO8nZl8hVUSRXAB5Varg0559292 intact-crc:AEB5164AD457824C|rigid:Nt8iXXbaPHN1BXO2W5Q8ymSHMcE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47160 uniprotkb:P32319 intact:EBI-25662|uniprotkb:D6VWU4|ensemblfungi:YJR125C intact:EBI-13123|uniprotkb:D6VPY3|ensemblfungi:YBL017C psi-mi:ent3_yeast(display_long)|uniprotkb:ENT3(gene name)|psi-mi:ENT3(display_short)|uniprotkb:J2048(orf name)|uniprotkb:YJR125C(locus name) psi-mi:vps10_yeast(display_long)|uniprotkb:PEP1(gene name)|psi-mi:PEP1(display_short)|uniprotkb:Vacuolar carboxypeptidase sorting receptor VPS10(gene name synonym)|uniprotkb:Carboxypeptidase Y receptor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 1(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 1(gene name synonym)|uniprotkb:Sortilin VPS10(gene name synonym)|uniprotkb:VPS10(gene name synonym)|uniprotkb:VPT1(gene name synonym)|uniprotkb:YBL03.22(orf name)|uniprotkb:YBL0302(orf name)|uniprotkb:YBL017C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321566|imex:IM-14275-697 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012659.1|sgd:S000003886|mint:P47160|dip:DIP-1304N|ensemblfungi:YJR125C(gene)|ensemblfungi:YJR125C_mRNA(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:3ONK|rcsb pdb:3ONL|reactome:R-SCE-8856825 refseq:NP_009536.1|sgd:S000000113|mint:P32319|dip:DIP-5900N|ensemblfungi:YBL017C(gene)|ensemblfungi:YBL017C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000423"(mitophagy)|go:"GO:0000425"(pexophagy)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048203"(vesicle targeting, trans-Golgi to endosome)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR036278 psi-mi:"MI:0469"(intact) crc64:D666ECB1C0D074FE crc64:C778A0400612ECF4 figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XSl8ItoXxrzs1OsGoIvQ8lBstQQ559292 rogid:dYYsekAaDw4SzmEUSe5tYb5a43M559292 intact-crc:DB50165FE1BD397D|rigid:ybhSgiASyviG6bj/A/ZIvjDmHbU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32319 uniprotkb:Q03687 intact:EBI-13123|uniprotkb:D6VPY3|ensemblfungi:YBL017C intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W psi-mi:vps10_yeast(display_long)|uniprotkb:PEP1(gene name)|psi-mi:PEP1(display_short)|uniprotkb:Vacuolar carboxypeptidase sorting receptor VPS10(gene name synonym)|uniprotkb:Carboxypeptidase Y receptor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 1(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 1(gene name synonym)|uniprotkb:Sortilin VPS10(gene name synonym)|uniprotkb:VPS10(gene name synonym)|uniprotkb:VPT1(gene name synonym)|uniprotkb:YBL03.22(orf name)|uniprotkb:YBL0302(orf name)|uniprotkb:YBL017C(locus name) psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321577|imex:IM-14275-698 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009536.1|sgd:S000000113|mint:P32319|dip:DIP-5900N|ensemblfungi:YBL017C(gene)|ensemblfungi:YBL017C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000423"(mitophagy)|go:"GO:0000425"(pexophagy)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048203"(vesicle targeting, trans-Golgi to endosome)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR036278 refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) psi-mi:"MI:0469"(intact) crc64:C778A0400612ECF4 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dYYsekAaDw4SzmEUSe5tYb5a43M559292 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 intact-crc:8E20C30507E6CD2D|rigid:RhtGJuGOYp5JIcdmgWNOhOuo5BY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32319 uniprotkb:Q03860 intact:EBI-13123|uniprotkb:D6VPY3|ensemblfungi:YBL017C intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:vps10_yeast(display_long)|uniprotkb:PEP1(gene name)|psi-mi:PEP1(display_short)|uniprotkb:Vacuolar carboxypeptidase sorting receptor VPS10(gene name synonym)|uniprotkb:Carboxypeptidase Y receptor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 1(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 1(gene name synonym)|uniprotkb:Sortilin VPS10(gene name synonym)|uniprotkb:VPS10(gene name synonym)|uniprotkb:VPT1(gene name synonym)|uniprotkb:YBL03.22(orf name)|uniprotkb:YBL0302(orf name)|uniprotkb:YBL017C(locus name) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321588|imex:IM-14275-699 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009536.1|sgd:S000000113|mint:P32319|dip:DIP-5900N|ensemblfungi:YBL017C(gene)|ensemblfungi:YBL017C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000423"(mitophagy)|go:"GO:0000425"(pexophagy)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048203"(vesicle targeting, trans-Golgi to endosome)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR036278 sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) crc64:C778A0400612ECF4 crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dYYsekAaDw4SzmEUSe5tYb5a43M559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:645E90CA783D3E2F|rigid:9RjvOxYy9z0wSmmIQMjPpF1LDlE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32319 uniprotkb:Q12016 intact:EBI-13123|uniprotkb:D6VPY3|ensemblfungi:YBL017C intact:EBI-29309|uniprotkb:D6W1T9|ensemblfungi:YOL129W psi-mi:vps10_yeast(display_long)|uniprotkb:PEP1(gene name)|psi-mi:PEP1(display_short)|uniprotkb:Vacuolar carboxypeptidase sorting receptor VPS10(gene name synonym)|uniprotkb:Carboxypeptidase Y receptor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 1(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 1(gene name synonym)|uniprotkb:Sortilin VPS10(gene name synonym)|uniprotkb:VPS10(gene name synonym)|uniprotkb:VPT1(gene name synonym)|uniprotkb:YBL03.22(orf name)|uniprotkb:YBL0302(orf name)|uniprotkb:YBL017C(locus name) psi-mi:vps68_yeast(display_long)|uniprotkb:YOL129W(locus name)|uniprotkb:VPS68(gene name)|psi-mi:VPS68(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321599|imex:IM-14275-700 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009536.1|sgd:S000000113|mint:P32319|dip:DIP-5900N|ensemblfungi:YBL017C(gene)|ensemblfungi:YBL017C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000423"(mitophagy)|go:"GO:0000425"(pexophagy)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048203"(vesicle targeting, trans-Golgi to endosome)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR036278 refseq:NP_014512.1|sgd:S000005489|dip:DIP-1732N|mint:Q12016|ensemblfungi:YOL129W(gene)|ensemblfungi:YOL129W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0034424"(Vps55/Vps68 complex)|interpro:IPR007919(Protein of unknown function UPF0220) psi-mi:"MI:0469"(intact) crc64:C778A0400612ECF4 crc64:4B21C846AB3BA2A7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dYYsekAaDw4SzmEUSe5tYb5a43M559292 rogid:I6sUyfNcLBsFG3OtDUfEqohxLB4559292 intact-crc:978C96E9E97E34EF|rigid:kLmi+7gWpfeMX5Jt/o5FQmtBLkM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92331 uniprotkb:P32319 intact:EBI-20483|uniprotkb:Q08483|uniprotkb:D6W2D1|uniprotkb:E9P8U6|ensemblfungi:YOR069W intact:EBI-13123|uniprotkb:D6VPY3|ensemblfungi:YBL017C psi-mi:vps5_yeast(display_long)|uniprotkb:VPS5(gene name)|psi-mi:VPS5(display_short)|uniprotkb:GRD2(gene name synonym)|uniprotkb:PEP10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 5(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 10(gene name synonym)|uniprotkb:VPT5(gene name synonym)|uniprotkb:YOR29-20(orf name)|uniprotkb:YOR069W(locus name) psi-mi:vps10_yeast(display_long)|uniprotkb:PEP1(gene name)|psi-mi:PEP1(display_short)|uniprotkb:Vacuolar carboxypeptidase sorting receptor VPS10(gene name synonym)|uniprotkb:Carboxypeptidase Y receptor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 1(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 1(gene name synonym)|uniprotkb:Sortilin VPS10(gene name synonym)|uniprotkb:VPS10(gene name synonym)|uniprotkb:VPT1(gene name synonym)|uniprotkb:YBL03.22(orf name)|uniprotkb:YBL0302(orf name)|uniprotkb:YBL017C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321610|imex:IM-14275-701 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014712.2|sgd:S000005595|ensemblfungi:YOR069W(gene)|ensemblfungi:YOR069W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0005768"(endosome)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|interpro:IPR001683(Phox-like)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028648|interpro:IPR035803|interpro:IPR036871|interpro:IPR037868|dip:DIP-1740N|mint:Q92331 refseq:NP_009536.1|sgd:S000000113|mint:P32319|dip:DIP-5900N|ensemblfungi:YBL017C(gene)|ensemblfungi:YBL017C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000423"(mitophagy)|go:"GO:0000425"(pexophagy)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048203"(vesicle targeting, trans-Golgi to endosome)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR036278 psi-mi:"MI:0469"(intact) - crc64:C778A0400612ECF4 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5aPSkQUJV1sfIc9Ql+wMP74Y3QI559292 rogid:dYYsekAaDw4SzmEUSe5tYb5a43M559292 intact-crc:7592CF4CBC5A70D0|rigid:RZlpQHih751xH9nO+Uzb9A+5QI8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32324 uniprotkb:P38009 intact:EBI-6333|uniprotkb:Q6JEF7|uniprotkb:D6VT19|ensemblfungi:YDR385W|ensemblfungi:YOR133W intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 psi-mi:ef2_yeast(display_long)|uniprotkb:EFT1(gene name)|psi-mi:EFT1(display_short)|uniprotkb:YOR133W(locus name)|uniprotkb:O3317(orf name)|uniprotkb:YOR3317W(orf name)|uniprotkb:EFT2(gene name)|psi-mi:EFT2(display_short)|uniprotkb:YDR385W(locus name)|uniprotkb:Translation elongation factor 2(gene name synonym)|uniprotkb:Eukaryotic elongation factor 2(gene name synonym)|uniprotkb:Ribosomal translocase(gene name synonym) psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321621|imex:IM-14275-702 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010673.1|refseq:NP_014776.1|sgd:S000005659|sgd:S000002793|ensemblfungi:YDR385W(gene)|ensemblfungi:YDR385W_mRNA(transcript)|ensemblfungi:YOR133W(gene)|ensemblfungi:YOR133W_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0019843"(rRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0051087"(chaperone binding)|go:"GO:1990145"(maintenance of translational fidelity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|mint:P32324|dip:DIP-4911N|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|rcsb pdb:1N0U|rcsb pdb:1N0V|rcsb pdb:1U2R|rcsb pdb:1ZM2|rcsb pdb:1ZM3|rcsb pdb:1ZM4|rcsb pdb:1ZM9|rcsb pdb:2E1R|rcsb pdb:2NPF|rcsb pdb:2P8W|rcsb pdb:2P8X|rcsb pdb:2P8Y|rcsb pdb:2P8Z|rcsb pdb:2ZIT|rcsb pdb:3B78|rcsb pdb:3B82|rcsb pdb:3B8H|rcsb pdb:3DNY|rcsb pdb:4V4B|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|reactome:R-SCE-156902|reactome:R-SCE-5358493|reactome:R-SCE-6798695 refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N psi-mi:"MI:0469"(intact) crc64:FD2F8073CB9B66AA crc64:8ABA71761B512242 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mlyt9YKZrGhGbsSlvxNJ0p1C67I559292 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 intact-crc:3B5DFE4DE3C2CA69|rigid:7bAagc0FTF5wLE8O2E58Ku/Stbc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32334 uniprotkb:Q3E776 intact:EBI-11328|uniprotkb:D6VUF0|ensemblfungi:YGR014W intact:EBI-2042805|uniprotkb:D6VQQ2|ensemblfungi:YBR255C-A psi-mi:msb2_yeast(display_long)|uniprotkb:MSB2(gene name)|psi-mi:MSB2(display_short)|uniprotkb:Multicopy suppressor of bud emergence 2(gene name synonym)|uniprotkb:Osmosensor MSB2(gene name synonym)|uniprotkb:YGR014W(locus name) psi-mi:yb255_yeast(display_long)|uniprotkb:YBR255C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321632|imex:IM-14275-703 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR014W(gene)|ensemblfungi:YGR014W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR039295|go:"GO:0009986"(cell surface)|refseq:NP_011528.3|sgd:S000003246|mint:P32334|dip:DIP-1455N sgd:S000007649|interpro:IPR038882|refseq:NP_116328.4|mint:Q3E776|ensemblfungi:YBR255C-A(gene)|ensemblfungi:YBR255C-A_mRNA(transcript)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UsebPCw3sBOg1xeiMmr80m7b4P4559292 rogid:LHd4ToffLuVn2nuqg93EsoO8ouo559292 intact-crc:B6FB14E6E441331A|rigid:gHqbQvwb1TA++Vd/el9hhEDo0RY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32334 uniprotkb:Q8TGU5 intact:EBI-11328|uniprotkb:D6VUF0|ensemblfungi:YGR014W intact:EBI-2042814|uniprotkb:D6VQU1|ensemblfungi:YBR296C-A psi-mi:msb2_yeast(display_long)|uniprotkb:MSB2(gene name)|psi-mi:MSB2(display_short)|uniprotkb:Multicopy suppressor of bud emergence 2(gene name synonym)|uniprotkb:Osmosensor MSB2(gene name synonym)|uniprotkb:YGR014W(locus name) psi-mi:yb296_yeast(display_long)|uniprotkb:YBR296C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321643|imex:IM-14275-704 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR014W(gene)|ensemblfungi:YGR014W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR039295|go:"GO:0009986"(cell surface)|refseq:NP_011528.3|sgd:S000003246|mint:P32334|dip:DIP-1455N sgd:S000028605|refseq:NP_878055.3|mint:Q8TGU5|ensemblfungi:YBR296C-A(gene)|ensemblfungi:YBR296C-A_mRNA(transcript)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UsebPCw3sBOg1xeiMmr80m7b4P4559292 rogid:DZubWD7lnwtea4Ne/bK1ITPFaJk559292 intact-crc:BB24535C003A0CBD|rigid:Jhb++OQEWXvTpxpyNjV6ugKe92k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32347 uniprotkb:P32347 intact:EBI-5711|uniprotkb:D6VS35|ensemblfungi:YDR047W intact:EBI-5711|uniprotkb:D6VS35|ensemblfungi:YDR047W psi-mi:dcup_yeast(display_long)|uniprotkb:HEM12(gene name)|psi-mi:HEM12(display_short)|uniprotkb:HEM6(gene name synonym)|uniprotkb:POP3(gene name synonym)|uniprotkb:YDR047W(locus name)|uniprotkb:YD9609.03(orf name) psi-mi:dcup_yeast(display_long)|uniprotkb:HEM12(gene name)|psi-mi:HEM12(display_short)|uniprotkb:HEM6(gene name synonym)|uniprotkb:POP3(gene name synonym)|uniprotkb:YDR047W(locus name)|uniprotkb:YD9609.03(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321654|imex:IM-14275-705 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002454|interpro:IPR006361(Uroporphyrinogen decarboxylase HemE)|interpro:IPR000257("Uroporphyrinogen decarboxylase (URO-D)")|refseq:NP_010332.3|interpro:IPR038071|mint:P32347|ensemblfungi:YDR047W(gene)|ensemblfungi:YDR047W_mRNA(transcript)|go:"GO:0004853"(uroporphyrinogen decarboxylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)|go:"GO:0006783"(heme biosynthetic process)|reactome:R-SCE-189451 sgd:S000002454|interpro:IPR006361(Uroporphyrinogen decarboxylase HemE)|interpro:IPR000257("Uroporphyrinogen decarboxylase (URO-D)")|refseq:NP_010332.3|interpro:IPR038071|mint:P32347|ensemblfungi:YDR047W(gene)|ensemblfungi:YDR047W_mRNA(transcript)|go:"GO:0004853"(uroporphyrinogen decarboxylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)|go:"GO:0006783"(heme biosynthetic process)|reactome:R-SCE-189451 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oSxr3qH8uPfXTyuyJRLCRUbPlH4559292 rogid:oSxr3qH8uPfXTyuyJRLCRUbPlH4559292 intact-crc:B148A260F3EE82A2|rigid:mP4rIZRAJpoPsJ9w1bYDOAzrJik false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32353 uniprotkb:P10614 intact:EBI-6554|uniprotkb:D6VY58|ensemblfungi:YLR056W intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:erg3_yeast(display_long)|uniprotkb:SYR1(gene name synonym)|uniprotkb:L2150(orf name)|uniprotkb:YLR056W(locus name)|uniprotkb:ERG3(gene name)|psi-mi:ERG3(display_short)|uniprotkb:PSO6(gene name synonym)|uniprotkb:Sterol-C5-desaturase(gene name synonym)|uniprotkb:"Ergosterol Delta(5,6) desaturase"(gene name synonym)|uniprotkb:C-5 sterol desaturase(gene name synonym) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321665|imex:IM-14275-706 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013157.1|sgd:S000004046|mint:P32353|dip:DIP-4136N|ensemblfungi:YLR056W(gene)|ensemblfungi:YLR056W_mRNA(transcript)|go:"GO:0000248"(C-5 sterol desaturase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0050046"("delta7-sterol 5(6)-desaturase activity")|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-SCE-6807047|reactome:R-SCE-6807062 refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zO926fj34KkGCJAI6vTmiICpUSc559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:CF0718BA4FA34DF2|rigid:KBX5l90H0ULyBNphm7Czqwao/AE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32353 uniprotkb:P32353 intact:EBI-6554|uniprotkb:D6VY58|ensemblfungi:YLR056W intact:EBI-6554|uniprotkb:D6VY58|ensemblfungi:YLR056W psi-mi:erg3_yeast(display_long)|uniprotkb:SYR1(gene name synonym)|uniprotkb:L2150(orf name)|uniprotkb:YLR056W(locus name)|uniprotkb:ERG3(gene name)|psi-mi:ERG3(display_short)|uniprotkb:PSO6(gene name synonym)|uniprotkb:Sterol-C5-desaturase(gene name synonym)|uniprotkb:"Ergosterol Delta(5,6) desaturase"(gene name synonym)|uniprotkb:C-5 sterol desaturase(gene name synonym) psi-mi:erg3_yeast(display_long)|uniprotkb:SYR1(gene name synonym)|uniprotkb:L2150(orf name)|uniprotkb:YLR056W(locus name)|uniprotkb:ERG3(gene name)|psi-mi:ERG3(display_short)|uniprotkb:PSO6(gene name synonym)|uniprotkb:Sterol-C5-desaturase(gene name synonym)|uniprotkb:"Ergosterol Delta(5,6) desaturase"(gene name synonym)|uniprotkb:C-5 sterol desaturase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321676|imex:IM-14275-707 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013157.1|sgd:S000004046|mint:P32353|dip:DIP-4136N|ensemblfungi:YLR056W(gene)|ensemblfungi:YLR056W_mRNA(transcript)|go:"GO:0000248"(C-5 sterol desaturase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0050046"("delta7-sterol 5(6)-desaturase activity")|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-SCE-6807047|reactome:R-SCE-6807062 refseq:NP_013157.1|sgd:S000004046|mint:P32353|dip:DIP-4136N|ensemblfungi:YLR056W(gene)|ensemblfungi:YLR056W_mRNA(transcript)|go:"GO:0000248"(C-5 sterol desaturase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0050046"("delta7-sterol 5(6)-desaturase activity")|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-SCE-6807047|reactome:R-SCE-6807062 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zO926fj34KkGCJAI6vTmiICpUSc559292 rogid:zO926fj34KkGCJAI6vTmiICpUSc559292 intact-crc:05962481B341173F|rigid:xOyVjo/WyD+KiQsvR00Cyfk0IwI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32353 uniprotkb:P54837 intact:EBI-6554|uniprotkb:D6VY58|ensemblfungi:YLR056W intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:erg3_yeast(display_long)|uniprotkb:SYR1(gene name synonym)|uniprotkb:L2150(orf name)|uniprotkb:YLR056W(locus name)|uniprotkb:ERG3(gene name)|psi-mi:ERG3(display_short)|uniprotkb:PSO6(gene name synonym)|uniprotkb:Sterol-C5-desaturase(gene name synonym)|uniprotkb:"Ergosterol Delta(5,6) desaturase"(gene name synonym)|uniprotkb:C-5 sterol desaturase(gene name synonym) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321687|imex:IM-14275-708 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013157.1|sgd:S000004046|mint:P32353|dip:DIP-4136N|ensemblfungi:YLR056W(gene)|ensemblfungi:YLR056W_mRNA(transcript)|go:"GO:0000248"(C-5 sterol desaturase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0050046"("delta7-sterol 5(6)-desaturase activity")|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-SCE-6807047|reactome:R-SCE-6807062 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zO926fj34KkGCJAI6vTmiICpUSc559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:A228E706E3BBF81F|rigid:yUOxjAWF7VXQRiLLfYLnp2yC6/o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32364 uniprotkb:Q12157 intact:EBI-17497|uniprotkb:D6VXK8|ensemblfungi:YKL079W intact:EBI-29698|uniprotkb:D6VRX9|ensemblfungi:YDL008W psi-mi:smy1_yeast(display_long)|uniprotkb:SMY1(gene name)|psi-mi:SMY1(display_short)|uniprotkb:YKL079W(locus name)|uniprotkb:YKL409(orf name)|uniprotkb:Suppressor protein SMY1(gene name synonym) psi-mi:apc11_yeast(display_long)|uniprotkb:D2900(orf name)|uniprotkb:YDL008W(locus name)|uniprotkb:APC11(gene name)|psi-mi:APC11(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321698|imex:IM-14275-709 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012844.1|sgd:S000001562|ensemblfungi:YKL079W(gene)|ensemblfungi:YKL079W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0043332"(mating projection tip)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|rcsb pdb:6IXQ|dip:DIP-4476N|mint:P32364 sgd:S000002166|refseq:NP_010276.3|dip:DIP-1130N|mint:Q12157|ensemblfungi:YDL008W(gene)|ensemblfungi:YDL008W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024991|reactome:R-SCE-983168 psi-mi:"MI:0469"(intact) - crc64:99F8E8C6BC841934 figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vLPZsddWowBykAxrC1c/SIv4bjI559292 rogid:4Y87RTVTCmu4TYy0VhAuAcCASk0559292 intact-crc:B33D2669E2EAC9A5|rigid:gzGvVDfNoYe4dIyv7q30SCzenFc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31412 uniprotkb:P32366 intact:EBI-20260|uniprotkb:D6VXK7|ensemblfungi:YKL080W intact:EBI-20201|uniprotkb:D6VZ81|ensemblfungi:YLR447C psi-mi:vatc_yeast(display_long)|uniprotkb:VMA5(gene name)|psi-mi:VMA5(display_short)|uniprotkb:VAT3(gene name synonym)|uniprotkb:VATC(gene name synonym)|uniprotkb:YKL410(orf name)|uniprotkb:YKL080W(locus name)|uniprotkb:Vacuolar proton pump subunit C(gene name synonym)|uniprotkb:V-ATPase 42 kDa subunit(gene name synonym) psi-mi:va0d_yeast(display_long)|uniprotkb:VMA6(gene name)|psi-mi:VMA6(display_short)|uniprotkb:YLR447C(locus name)|uniprotkb:L9324.8(orf name)|uniprotkb:Vacuolar proton pump subunit d(gene name synonym)|uniprotkb:V-ATPase 39 kDa subunit(gene name synonym)|uniprotkb:V-ATPase subunit M39(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321709|imex:IM-14275-710 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012843.1|sgd:S000001563|ensemblfungi:YKL080W(gene)|ensemblfungi:YKL080W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004907(ATPase, V1 complex, subunit C)|interpro:IPR036132|rcsb pdb:1U7L|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4DL0|rcsb pdb:4EFA|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-4701N|mint:P31412 sgd:S000004439|refseq:NP_013552.3|mint:P32366|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR036079|interpro:IPR044911|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|ensemblfungi:YLR447C(gene)|ensemblfungi:YLR447C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|rcsb pdb:6PE4|dip:DIP-1737N psi-mi:"MI:0469"(intact) crc64:0CD1B814046C377E crc64:53A19450CAF35632 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:NBI0upCB5yxAyMQgccBcLhjZk8s559292 rogid:Ux3Cd8Fl9t/GGgcKAzJevZQFWnE559292 intact-crc:44E124BDDAF459DC|rigid:GVjZjPVOnEBGeVMdwDZ/SzrtqKE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32610 uniprotkb:P32366 intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W intact:EBI-20201|uniprotkb:D6VZ81|ensemblfungi:YLR447C psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym) psi-mi:va0d_yeast(display_long)|uniprotkb:VMA6(gene name)|psi-mi:VMA6(display_short)|uniprotkb:YLR447C(locus name)|uniprotkb:L9324.8(orf name)|uniprotkb:Vacuolar proton pump subunit d(gene name synonym)|uniprotkb:V-ATPase 39 kDa subunit(gene name synonym)|uniprotkb:V-ATPase subunit M39(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321731|imex:IM-14275-712 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610 sgd:S000004439|refseq:NP_013552.3|mint:P32366|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR036079|interpro:IPR044911|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|ensemblfungi:YLR447C(gene)|ensemblfungi:YLR447C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|rcsb pdb:6PE4|dip:DIP-1737N psi-mi:"MI:0469"(intact) crc64:FDE93E1FAF0AEC5B crc64:53A19450CAF35632 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292 rogid:Ux3Cd8Fl9t/GGgcKAzJevZQFWnE559292 intact-crc:E694FC8C272CE57C|rigid:EkX6cac6FMpGUEVHAeJ+4MB0GxY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32366 uniprotkb:P32563 intact:EBI-20201|uniprotkb:D6VZ81|ensemblfungi:YLR447C intact:EBI-20455|uniprotkb:D6W2X0|ensemblfungi:YOR270C psi-mi:va0d_yeast(display_long)|uniprotkb:VMA6(gene name)|psi-mi:VMA6(display_short)|uniprotkb:YLR447C(locus name)|uniprotkb:L9324.8(orf name)|uniprotkb:Vacuolar proton pump subunit d(gene name synonym)|uniprotkb:V-ATPase 39 kDa subunit(gene name synonym)|uniprotkb:V-ATPase subunit M39(gene name synonym) psi-mi:vph1_yeast(display_long)|uniprotkb:VPH1(gene name)|psi-mi:VPH1(display_short)|uniprotkb:Vacuolar proton pump a subunit(gene name synonym)|uniprotkb:V-ATPase 95 kDa subunit(gene name synonym)|uniprotkb:Vacuolar pH protein 1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase subunit a 1(gene name synonym)|uniprotkb:YOR270C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321720|imex:IM-14275-711 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004439|refseq:NP_013552.3|mint:P32366|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR036079|interpro:IPR044911|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|ensemblfungi:YLR447C(gene)|ensemblfungi:YLR447C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|rcsb pdb:6PE4|dip:DIP-1737N sgd:S000005796|refseq:NP_014913.3|ensemblfungi:YOR270C(gene)|ensemblfungi:YOR270C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0034622"|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:0071469"(cellular response to alkaline pH)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|rcsb pdb:2JTW|rcsb pdb:2NVJ|rcsb pdb:2RPW|rcsb pdb:3J9T|go:"GO:0007035"(vacuolar acidification)|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5I1M|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6HH0|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2960N|mint:P32563 psi-mi:"MI:0469"(intact) crc64:53A19450CAF35632 crc64:77709A914410CD4D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ux3Cd8Fl9t/GGgcKAzJevZQFWnE559292 rogid:c+aKW/ZUnBlGW7ZqOLD/0mpICdQ559292 intact-crc:91322E1CA6A3A406|rigid:09YDVLEiuSJ7h6po9FyS9scqtqY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39111 uniprotkb:P32366 intact:EBI-20272|uniprotkb:D6VUF5|ensemblfungi:YGR020C intact:EBI-20201|uniprotkb:D6VZ81|ensemblfungi:YLR447C psi-mi:vatf_yeast(display_long)|uniprotkb:VMA7(gene name)|psi-mi:VMA7(display_short)|uniprotkb:YGR020C(locus name)|uniprotkb:Vacuolar proton pump subunit F(gene name synonym)|uniprotkb:V-ATPase 14 kDa subunit(gene name synonym) psi-mi:va0d_yeast(display_long)|uniprotkb:VMA6(gene name)|psi-mi:VMA6(display_short)|uniprotkb:YLR447C(locus name)|uniprotkb:L9324.8(orf name)|uniprotkb:Vacuolar proton pump subunit d(gene name synonym)|uniprotkb:V-ATPase 39 kDa subunit(gene name synonym)|uniprotkb:V-ATPase subunit M39(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321742|imex:IM-14275-713 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011534.1|sgd:S000003252|ensemblfungi:YGR020C(gene)|ensemblfungi:YGR020C_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016020"(membrane)|go:"GO:0042625"(ATPase-coupled ion transmembrane transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005772(ATPase, V1 complex, subunit F, eukaryotic)|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|interpro:IPR036906|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4IX9|rcsb pdb:4RND|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2077N|mint:P39111 sgd:S000004439|refseq:NP_013552.3|mint:P32366|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR036079|interpro:IPR044911|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|ensemblfungi:YLR447C(gene)|ensemblfungi:YLR447C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|rcsb pdb:6PE4|dip:DIP-1737N psi-mi:"MI:0469"(intact) crc64:D21EC0980EB99DFF crc64:53A19450CAF35632 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VtthQl2jj9fpjv3psX0YUNbIAKU559292 rogid:Ux3Cd8Fl9t/GGgcKAzJevZQFWnE559292 intact-crc:48A01098306E19A4|rigid:czuWEFSwHYB3b6vwZ1M9Qxzbbt4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32366 uniprotkb:P41806 intact:EBI-20201|uniprotkb:D6VZ81|ensemblfungi:YLR447C intact:EBI-20323|uniprotkb:D6VUN7|uniprotkb:Q6Q5Q3|ensemblfungi:YGR105W psi-mi:va0d_yeast(display_long)|uniprotkb:VMA6(gene name)|psi-mi:VMA6(display_short)|uniprotkb:YLR447C(locus name)|uniprotkb:L9324.8(orf name)|uniprotkb:Vacuolar proton pump subunit d(gene name synonym)|uniprotkb:V-ATPase 39 kDa subunit(gene name synonym)|uniprotkb:V-ATPase subunit M39(gene name synonym) psi-mi:vma21_yeast(display_long)|uniprotkb:VMA21(gene name)|psi-mi:VMA21(display_short)|uniprotkb:YGR105W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321753|imex:IM-14275-714 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004439|refseq:NP_013552.3|mint:P32366|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR036079|interpro:IPR044911|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|ensemblfungi:YLR447C(gene)|ensemblfungi:YLR447C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|rcsb pdb:6PE4|dip:DIP-1737N sgd:S000003337|refseq:NP_011619.3|ensemblfungi:YGR105W(gene)|ensemblfungi:YGR105W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|interpro:IPR019013|dip:DIP-5526N|mint:P41806 psi-mi:"MI:0469"(intact) crc64:53A19450CAF35632 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ux3Cd8Fl9t/GGgcKAzJevZQFWnE559292 rogid:Ailhh4PtjuOy5Jiwx8aN7cHFddk559292 intact-crc:1A7F8C5BEBE77CDF|rigid:ufY/40OL2UrkPKjrEFQK+0bRfG8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41807 uniprotkb:P32366 intact:EBI-20281|uniprotkb:D6W446|ensemblfungi:YPR036W intact:EBI-20201|uniprotkb:D6VZ81|ensemblfungi:YLR447C psi-mi:vath_yeast(display_long)|uniprotkb:YP3085.02(orf name)|uniprotkb:VMA13(gene name)|psi-mi:VMA13(display_short)|uniprotkb:CLS11(gene name synonym)|uniprotkb:YPR036W(locus name)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 54 kDa subunit(gene name synonym) psi-mi:va0d_yeast(display_long)|uniprotkb:VMA6(gene name)|psi-mi:VMA6(display_short)|uniprotkb:YLR447C(locus name)|uniprotkb:L9324.8(orf name)|uniprotkb:Vacuolar proton pump subunit d(gene name synonym)|uniprotkb:V-ATPase 39 kDa subunit(gene name synonym)|uniprotkb:V-ATPase subunit M39(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321764|imex:IM-14275-715 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015361.1|sgd:S000006240|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|rcsb pdb:1HO8|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YPR036W(gene)|ensemblfungi:YPR036W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|dip:DIP-6640N|mint:P41807 sgd:S000004439|refseq:NP_013552.3|mint:P32366|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR036079|interpro:IPR044911|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|ensemblfungi:YLR447C(gene)|ensemblfungi:YLR447C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|rcsb pdb:6PE4|dip:DIP-1737N psi-mi:"MI:0469"(intact) crc64:54131FF9C2C87594 crc64:53A19450CAF35632 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kEXWvOsnTk0WdgGOny+mufz4lTo559292 rogid:Ux3Cd8Fl9t/GGgcKAzJevZQFWnE559292 intact-crc:85C6877DCE13228B|rigid:IZPOURBp3wEaE0pKmo8sqh5xMS8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32366 uniprotkb:P53262 intact:EBI-20201|uniprotkb:D6VZ81|ensemblfungi:YLR447C intact:EBI-2061527|uniprotkb:D6VUN8|ensemblfungi:YGR106C psi-mi:va0d_yeast(display_long)|uniprotkb:VMA6(gene name)|psi-mi:VMA6(display_short)|uniprotkb:YLR447C(locus name)|uniprotkb:L9324.8(orf name)|uniprotkb:Vacuolar proton pump subunit d(gene name synonym)|uniprotkb:V-ATPase 39 kDa subunit(gene name synonym)|uniprotkb:V-ATPase subunit M39(gene name synonym) psi-mi:voa1_yeast(display_long)|uniprotkb:YGR106C(locus name)|uniprotkb:VOA1(gene name)|psi-mi:VOA1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321775|imex:IM-14275-716 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004439|refseq:NP_013552.3|mint:P32366|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR036079|interpro:IPR044911|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|ensemblfungi:YLR447C(gene)|ensemblfungi:YLR447C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|rcsb pdb:6PE4|dip:DIP-1737N sgd:S000003338|refseq:NP_011620.1|mint:P53262|ensemblfungi:YGR106C(gene)|ensemblfungi:YGR106C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034622"|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|rcsb pdb:6PE4|rcsb pdb:6PE5 psi-mi:"MI:0469"(intact) crc64:53A19450CAF35632 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ux3Cd8Fl9t/GGgcKAzJevZQFWnE559292 rogid:lKLIonttSEX36IQaIKlzxS/Cdxg559292 intact-crc:F9E369ADCA381F6E|rigid:aCivTVbvbHSTAfhpYktPQPyDYl8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32379 uniprotkb:P21242 intact:EBI-13971|ensemblfungi:YGR253C|uniprotkb:D6VV33 intact:EBI-13963|ensemblfungi:YOR362C|uniprotkb:D6W357 psi-mi:psa5_yeast(display_long)|uniprotkb:PUP2(gene name)|psi-mi:PUP2(display_short)|uniprotkb:DOA5(gene name synonym)|uniprotkb:YGR253C(locus name)|uniprotkb:G9155(orf name)|uniprotkb:Proteasome component PUP2(gene name synonym)|uniprotkb:Macropain subunit PUP2(gene name synonym)|uniprotkb:Proteinase YSCE subunit PUP2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PUP2(gene name synonym) psi-mi:psa7_yeast(display_long)|uniprotkb:PRE10(gene name)|psi-mi:PRE10(display_short)|uniprotkb:PRC1(gene name synonym)|uniprotkb:PRS1(gene name synonym)|uniprotkb:O6650(orf name)|uniprotkb:YOR362C(locus name)|uniprotkb:Proteasome component C1(gene name synonym)|uniprotkb:Macropain subunit C1(gene name synonym)|uniprotkb:Proteinase YSCE subunit 1(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321786|imex:IM-14275-717 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y69|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|refseq:NP_011769.1|sgd:S000003485|ensemblfungi:YGR253C(gene)|ensemblfungi:YGR253C_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR033812|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2Z5C|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:3UN4|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QVN|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QLV|rcsb pdb:4QVY|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|mint:P32379|dip:DIP-1193N ensemblfungi:YOR362C(gene)|ensemblfungi:YOR362C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR029055|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR037555|interpro:IPR001353(20S proteasome, A and B subunits)|rcsb pdb:1FNT|interpro:IPR023332|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QW6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4Y7Y|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5A5B|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5D0X|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L5E|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5L67|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6HTC|rcsb pdb:6FVW|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6FVX|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6HV4|rcsb pdb:6G8M|rcsb pdb:6HV5|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|rcsb pdb:6HW5|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-5668541|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:1G0U|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:3SDI|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QLS|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|refseq:NP_015007.1|sgd:S000005889|mint:P21242|dip:DIP-1526N psi-mi:"MI:0469"(intact) crc64:E8EDEB212BF4EC6E crc64:1E51D904CF336747 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:d9WDpDu+8VHYVXV0dRDCcL6UaSk559292 rogid:tVLLjztJDttaRM40dHah/J06g0E559292 intact-crc:8D624D9A5DEDD463|rigid:iX/ZZVOrroSjtJnn0SWMUNLtpGw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11986 uniprotkb:P32381 intact:EBI-9257|ensemblfungi:YJL153C|uniprotkb:D6VW34 intact:EBI-2927|uniprotkb:D6VRW3|ensemblfungi:YDL029W psi-mi:ino1_yeast(display_long)|uniprotkb:INO1(gene name)|psi-mi:INO1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym)|uniprotkb:J0610(orf name)|uniprotkb:YJL153C(locus name) psi-mi:arp2_yeast(display_long)|uniprotkb:ACT2(gene name synonym)|uniprotkb:YDL029W(locus name)|uniprotkb:D2778(orf name)|uniprotkb:ARP2(gene name)|psi-mi:ARP2(display_short)|uniprotkb:Actin-like protein ARP2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321797|imex:IM-14275-718 author score:99.26 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1P1K|ensemblfungi:YJL153C(gene)|ensemblfungi:YJL153C_mRNA(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|rcsb pdb:1JKF|rcsb pdb:1JKI|rcsb pdb:1LA2|rcsb pdb:1P1F|rcsb pdb:1P1H|rcsb pdb:1P1I|rcsb pdb:1P1J|rcsb pdb:1RM0|reactome:R-SCE-1855183|refseq:NP_012382.2|sgd:S000003689|dip:DIP-5687N|mint:P11986 refseq:NP_010255.1|sgd:S000002187|dip:DIP-2217N|mint:P32381|ensemblfungi:YDL029W(gene)|ensemblfungi:YDL029W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-6798695|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:282E2AE5D156289D crc64:4C9E8952B477A1B9 figure legend:tables S3 and S4|author-confidence:99.26|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3OB3q28fOVxXSBMwMpLe2c1g8p8559292 rogid:baSDcw/PZH3Z8YHhIcYqtlNO3mw559292 intact-crc:9ACCF880D0492E4D|rigid:ToVtebV7n9Wbgv3P2KwE3uCunt4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32381 uniprotkb:P37012 intact:EBI-2927|uniprotkb:D6VRW3|ensemblfungi:YDL029W intact:EBI-13296|uniprotkb:D6VZS7|ensemblfungi:YMR105C psi-mi:arp2_yeast(display_long)|uniprotkb:ACT2(gene name synonym)|uniprotkb:YDL029W(locus name)|uniprotkb:D2778(orf name)|uniprotkb:ARP2(gene name)|psi-mi:ARP2(display_short)|uniprotkb:Actin-like protein ARP2(gene name synonym) psi-mi:pgm2_yeast(display_long)|uniprotkb:PGM2(gene name)|psi-mi:PGM2(display_short)|uniprotkb:GAL5(gene name synonym)|uniprotkb:YMR105C(locus name)|uniprotkb:YM9718.04C(orf name)|uniprotkb:Glucose phosphomutase 2(gene name synonym)|uniprotkb:"D-glucose-1,6-diphosphate:D-glucose-1-phosphate phosphotransferase"(gene name synonym)|uniprotkb:GA-5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321808|imex:IM-14275-719 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010255.1|sgd:S000002187|dip:DIP-2217N|mint:P32381|ensemblfungi:YDL029W(gene)|ensemblfungi:YDL029W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-6798695|reactome:R-SCE-8856828 refseq:NP_013823.1|sgd:S000004711|mint:P37012|dip:DIP-6499N|ensemblfungi:YMR105C(gene)|ensemblfungi:YMR105C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004614"(phosphoglucomutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019255"(glucose 1-phosphate metabolic process)|go:"GO:0019388"(galactose catabolic process)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR036900 psi-mi:"MI:0469"(intact) crc64:4C9E8952B477A1B9 crc64:45B78AFF8197645E figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:baSDcw/PZH3Z8YHhIcYqtlNO3mw559292 rogid:miT4vpKTbsa/OfXIppW6h1+TbPs559292 intact-crc:240D3DB8073F2B03|rigid:5LN5vmvaEpfx9VxpgxUrtrA9m9Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37370 uniprotkb:P32381 intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C intact:EBI-2927|uniprotkb:D6VRW3|ensemblfungi:YDL029W psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:arp2_yeast(display_long)|uniprotkb:ACT2(gene name synonym)|uniprotkb:YDL029W(locus name)|uniprotkb:D2778(orf name)|uniprotkb:ARP2(gene name)|psi-mi:ARP2(display_short)|uniprotkb:Actin-like protein ARP2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321819|imex:IM-14275-720 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370 refseq:NP_010255.1|sgd:S000002187|dip:DIP-2217N|mint:P32381|ensemblfungi:YDL029W(gene)|ensemblfungi:YDL029W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-6798695|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:24C7522D5B1CA1C8 crc64:4C9E8952B477A1B9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 rogid:baSDcw/PZH3Z8YHhIcYqtlNO3mw559292 intact-crc:BD4D5FD58561C073|rigid:CP7d/yFxBqnyk/7+ER2zms8v8gk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32381 uniprotkb:P38328 intact:EBI-2927|uniprotkb:D6VRW3|ensemblfungi:YDL029W intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C psi-mi:arp2_yeast(display_long)|uniprotkb:ACT2(gene name synonym)|uniprotkb:YDL029W(locus name)|uniprotkb:D2778(orf name)|uniprotkb:ARP2(gene name)|psi-mi:ARP2(display_short)|uniprotkb:Actin-like protein ARP2(gene name synonym) psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321830|imex:IM-14275-721 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010255.1|sgd:S000002187|dip:DIP-2217N|mint:P32381|ensemblfungi:YDL029W(gene)|ensemblfungi:YDL029W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-6798695|reactome:R-SCE-8856828 sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:4C9E8952B477A1B9 crc64:D75C6BB8EC35EEDF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:baSDcw/PZH3Z8YHhIcYqtlNO3mw559292 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 intact-crc:076267A0F319D425|rigid:p5AOC+HH1/AeV4dK1SH79I/7pdI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32381 uniprotkb:P53731 intact:EBI-2927|uniprotkb:D6VRW3|ensemblfungi:YDL029W intact:EBI-2770|uniprotkb:D6W1L1|ensemblfungi:YNR035C psi-mi:arp2_yeast(display_long)|uniprotkb:ACT2(gene name synonym)|uniprotkb:YDL029W(locus name)|uniprotkb:D2778(orf name)|uniprotkb:ARP2(gene name)|psi-mi:ARP2(display_short)|uniprotkb:Actin-like protein ARP2(gene name synonym) psi-mi:arpc2_yeast(display_long)|uniprotkb:ARC35(gene name)|psi-mi:ARC35(display_short)|uniprotkb:YNR035C(locus name)|uniprotkb:N3296(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321841|imex:IM-14275-722 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010255.1|sgd:S000002187|dip:DIP-2217N|mint:P32381|ensemblfungi:YDL029W(gene)|ensemblfungi:YDL029W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-6798695|reactome:R-SCE-8856828 refseq:NP_014433.1|sgd:S000005318|dip:DIP-2304N|mint:P53731|ensemblfungi:YNR035C(gene)|ensemblfungi:YNR035C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072697"(protein localization to cell cortex)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:4C9E8952B477A1B9 crc64:9AF71A93688729F6 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:baSDcw/PZH3Z8YHhIcYqtlNO3mw559292 rogid:URdgP2srz1O44fNGQh18L7bzC+c559292 intact-crc:105308A231207ACC|rigid:ScLIS6IR06hCHFKaRWaZqDpvB0o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32381 uniprotkb:Q04439 intact:EBI-2927|uniprotkb:D6VRW3|ensemblfungi:YDL029W intact:EBI-11687|ensemblfungi:YMR109W|uniprotkb:D6VZT2 psi-mi:arp2_yeast(display_long)|uniprotkb:ACT2(gene name synonym)|uniprotkb:YDL029W(locus name)|uniprotkb:D2778(orf name)|uniprotkb:ARP2(gene name)|psi-mi:ARP2(display_short)|uniprotkb:Actin-like protein ARP2(gene name synonym) psi-mi:myo5_yeast(display_long)|uniprotkb:MYO5(gene name)|psi-mi:MYO5(display_short)|uniprotkb:YMR109W(locus name)|uniprotkb:YM9718.08(orf name)|uniprotkb:Class I unconventional myosin MYO5(gene name synonym)|uniprotkb:Type I myosin MYO5(gene name synonym)|uniprotkb:Actin-dependent myosin-I MYO5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321852|imex:IM-14275-723 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010255.1|sgd:S000002187|dip:DIP-2217N|mint:P32381|ensemblfungi:YDL029W(gene)|ensemblfungi:YDL029W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-6798695|reactome:R-SCE-8856828 ensemblfungi:YMR109W_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0009651"(response to salt stress)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051286"(cell tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071944"(cell periphery)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035535|ensemblfungi:YMR109W(gene)|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|rcsb pdb:1YP5|rcsb pdb:1ZUY|refseq:NP_013827.1|sgd:S000004715|mint:Q04439|dip:DIP-2222N psi-mi:"MI:0469"(intact) crc64:4C9E8952B477A1B9 crc64:DFFB9EC16B61CD29 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:baSDcw/PZH3Z8YHhIcYqtlNO3mw559292 rogid:n/Po/L9Xd7LP+fY39QaqP/s5US4559292 intact-crc:0794AA6D5CDB8A3B|rigid:TRZv97/yXUnMZZE0WXQffyTzP3E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05933 uniprotkb:P32381 intact:EBI-2764|uniprotkb:D6VZ07|ensemblfungi:YLR370C intact:EBI-2927|uniprotkb:D6VRW3|ensemblfungi:YDL029W psi-mi:arpc3_yeast(display_long)|uniprotkb:ARC18(gene name)|psi-mi:ARC18(display_short)|uniprotkb:YLR370C(locus name)|uniprotkb:L8039.15(orf name)|uniprotkb:Arp2/3 complex 21 kDa subunit(gene name synonym) psi-mi:arp2_yeast(display_long)|uniprotkb:ACT2(gene name synonym)|uniprotkb:YDL029W(locus name)|uniprotkb:D2778(orf name)|uniprotkb:ARP2(gene name)|psi-mi:ARP2(display_short)|uniprotkb:Actin-like protein ARP2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321863|imex:IM-14275-724 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004362|refseq:NP_013474.3|dip:DIP-2218N|mint:Q05933|ensemblfungi:YLR370C(gene)|ensemblfungi:YLR370C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR007204(ARP2/3 complex, 21 kDa p21-Arc subunit)|interpro:IPR036753|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 refseq:NP_010255.1|sgd:S000002187|dip:DIP-2217N|mint:P32381|ensemblfungi:YDL029W(gene)|ensemblfungi:YDL029W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-6798695|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:456EABC2B9CC4860 crc64:4C9E8952B477A1B9 figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Fj4cwULcw1TK5uS1lJczcNc5gns559292 rogid:baSDcw/PZH3Z8YHhIcYqtlNO3mw559292 intact-crc:520F6D7AF7357F97|rigid:M9128B2lAXfaxRVfpRYSYcDzeZo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32381 uniprotkb:Q12156 intact:EBI-2927|uniprotkb:D6VRW3|ensemblfungi:YDL029W intact:EBI-30371|uniprotkb:D6VS49|ensemblfungi:YDR063W psi-mi:arp2_yeast(display_long)|uniprotkb:ACT2(gene name synonym)|uniprotkb:YDL029W(locus name)|uniprotkb:D2778(orf name)|uniprotkb:ARP2(gene name)|psi-mi:ARP2(display_short)|uniprotkb:Actin-like protein ARP2(gene name synonym) psi-mi:aim7_yeast(display_long)|uniprotkb:AIM7(gene name)|psi-mi:AIM7(display_short)|uniprotkb:D4245(orf name)|uniprotkb:YDR063W(locus name)|uniprotkb:Altered inheritance rate of mitochondria protein 7(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321874|imex:IM-14275-725 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010255.1|sgd:S000002187|dip:DIP-2217N|mint:P32381|ensemblfungi:YDL029W(gene)|ensemblfungi:YDL029W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-6798695|reactome:R-SCE-8856828 refseq:NP_010348.1|sgd:S000002470|dip:DIP-1818N|mint:Q12156|ensemblfungi:YDR063W(gene)|ensemblfungi:YDR063W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0071846"(actin filament debranching)|go:"GO:0071933"(Arp2/3 complex binding)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR011171(Glia maturation factor beta)|interpro:IPR029006|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) crc64:4C9E8952B477A1B9 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:baSDcw/PZH3Z8YHhIcYqtlNO3mw559292 rogid:gNpFPaIObSMCgvbNabMJOjJMjco559292 intact-crc:E1CA2D59B055B728|rigid:foXFvhvkP2wCJgKYWclwNMRDd9A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12446 uniprotkb:P32381 intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W intact:EBI-2927|uniprotkb:D6VRW3|ensemblfungi:YDL029W psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name) psi-mi:arp2_yeast(display_long)|uniprotkb:ACT2(gene name synonym)|uniprotkb:YDL029W(locus name)|uniprotkb:D2778(orf name)|uniprotkb:ARP2(gene name)|psi-mi:ARP2(display_short)|uniprotkb:Actin-like protein ARP2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321885|imex:IM-14275-726 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446 refseq:NP_010255.1|sgd:S000002187|dip:DIP-2217N|mint:P32381|ensemblfungi:YDL029W(gene)|ensemblfungi:YDL029W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-6798695|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:4488355563AA2645 crc64:4C9E8952B477A1B9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292 rogid:baSDcw/PZH3Z8YHhIcYqtlNO3mw559292 intact-crc:A281B50FB1CEF153|rigid:rcNxa7O2IjsT6eoGdypqLlqUy3E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06102 uniprotkb:P32445 intact:EBI-12165|uniprotkb:D6VVP4|uniprotkb:Q6B233|ensemblfungi:YIL038C intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A psi-mi:not3_yeast(display_long)|uniprotkb:NOT3(gene name)|psi-mi:NOT3(display_short)|uniprotkb:YIL038C(locus name) psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321896|imex:IM-14275-727 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR038635|interpro:IPR040168|ensemblfungi:YIL038C(gene)|ensemblfungi:YIL038C_mRNA(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|refseq:NP_012226.3|sgd:S000001300|dip:DIP-2256N|mint:P06102 refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 psi-mi:"MI:0469"(intact) crc64:69B76694FCC6846F crc64:9F913C2FC9EF6E82 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:EfakZPDNU3FZeI5+rnu7YV1UsCg559292 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 intact-crc:612EBFF86EFA8468|rigid:PsxTlhjCTpQMvtch/1nIXANkey8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32445 uniprotkb:P10823 intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321907|imex:IM-14275-728 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) crc64:9F913C2FC9EF6E82 crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:24C34B55BBD8A224|rigid:eEeNxs0yPBtp/yH74GQiTuv6Lfg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32445 uniprotkb:P19807 intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321918|imex:IM-14275-729 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) crc64:9F913C2FC9EF6E82 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:0C08DF2E4744114A|rigid:eDWuZV9jHpYcnvv7XFAhraU58C0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32445 uniprotkb:P25655 intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321929|imex:IM-14275-730 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 psi-mi:"MI:0469"(intact) crc64:9F913C2FC9EF6E82 crc64:5B2AE15BCF95E009 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 intact-crc:253F549A88C1EDFD|rigid:nn+Hhd2QbYuqxC36evRLkAwYRrc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32588 uniprotkb:P32445 intact:EBI-14231|ensemblfungi:YNL016W|uniprotkb:D6W1G2 intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A psi-mi:pub1_yeast(display_long)|uniprotkb:ARS consensus-binding protein ACBP-60(gene name synonym)|uniprotkb:Poly uridylate-binding protein(gene name synonym)|uniprotkb:PUB1(gene name)|psi-mi:PUB1(display_short)|uniprotkb:RNP1(gene name synonym)|uniprotkb:YNL016W(locus name)|uniprotkb:N2842(orf name) psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321940|imex:IM-14275-731 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014382.1|sgd:S000004961|ensemblfungi:YNL016W(gene)|ensemblfungi:YNL016W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043488"(regulation of mRNA stability)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034509|interpro:IPR034639|interpro:IPR035979|rcsb pdb:2LA4|rcsb pdb:3MD1|rcsb pdb:3MD3|rcsb pdb:6Z29|mint:P32588|dip:DIP-5480N refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 psi-mi:"MI:0469"(intact) crc64:3B81A7735505D3CA crc64:9F913C2FC9EF6E82 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8xFMuEva7leVYDKg3WOmvPtRTFk559292 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 intact-crc:74431329CC0146F1|rigid:HmRixcS5rk7wPJuBu1boAhGznuE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34761 uniprotkb:P32445 intact:EBI-20537|uniprotkb:D6W0Z0|ensemblfungi:YNL197C intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A psi-mi:whi3_yeast(display_long)|uniprotkb:WHI3(gene name)|psi-mi:WHI3(display_short)|uniprotkb:N1382(orf name)|uniprotkb:YNL197C(locus name) psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321951|imex:IM-14275-732 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014202.1|sgd:S000005141|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|ensemblfungi:YNL197C(gene)|ensemblfungi:YNL197C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0032106"(positive regulation of response to extracellular stimulus)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0061013"(regulation of mRNA catabolic process)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071554"(cell wall organization or biogenesis)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P34761 refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 psi-mi:"MI:0469"(intact) - crc64:9F913C2FC9EF6E82 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Xpn0uJiaylcupy9qYDLa0V++z6A559292 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 intact-crc:A42F47EEA3D2EE01|rigid:m4XxBCJH5jzTsfVN5d+5Tgqz8LE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35732 uniprotkb:P32445 intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321962|imex:IM-14275-733 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 psi-mi:"MI:0469"(intact) crc64:05734E2D0B7389AC crc64:9F913C2FC9EF6E82 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 intact-crc:2F7A56FCCA770FFE|rigid:HG3ZQZkpW+On/YjjFfpgO8uYlFc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P32445 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321973|imex:IM-14275-734 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 psi-mi:"MI:0469"(intact) - crc64:9F913C2FC9EF6E82 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 intact-crc:9155670E33BA9450|rigid:MS+rlNKOFXIPK2zS79VdCdEZkb8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:P32445 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321984|imex:IM-14275-735 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 psi-mi:"MI:0469"(intact) - crc64:9F913C2FC9EF6E82 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 intact-crc:B30FA586A4984F04|rigid:nNR3J0ZupDf0PAKeZiMOXXBYrqo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32445 uniprotkb:P39008 intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6321995|imex:IM-14275-736 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N psi-mi:"MI:0469"(intact) crc64:9F913C2FC9EF6E82 crc64:F3CAF97106A65933 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 intact-crc:519181E0D9D40D67|rigid:fOSqmApuzM1Q2qdpitwEMxQRpo8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32445 uniprotkb:P40070 intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322006|imex:IM-14275-737 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:9F913C2FC9EF6E82 crc64:69CAC1F01D5BFA98 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 intact-crc:BD0C1224EBF214A3|rigid:TY+nX8axdxLA1kYHP03zoD+EoTU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32445 uniprotkb:P45978 intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A intact:EBI-16691|ensemblfungi:YPR129W|uniprotkb:D6W4C6 psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:scd6_yeast(display_long)|uniprotkb:P9659.10(orf name)|uniprotkb:YPR129W(locus name)|uniprotkb:SCD6(gene name)|psi-mi:SCD6(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322017|imex:IM-14275-738 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 ensemblfungi:YPR129W(gene)|ensemblfungi:YPR129W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:0003729"(mRNA binding)|interpro:IPR025609|refseq:NP_015454.1|sgd:S000006333|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR019050|interpro:IPR025761|interpro:IPR025762|interpro:IPR025768|mint:P45978 psi-mi:"MI:0469"(intact) crc64:9F913C2FC9EF6E82 - figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 rogid:QRNg1nbLjsxR5twooPvrSPZTWO0559292 intact-crc:845A8175C34052E0|rigid:3DcEXc+y6g9LTi5VzeKaogrBufI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32445 uniprotkb:P50276 intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322028|imex:IM-14275-739 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) crc64:9F913C2FC9EF6E82 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:53D728D37E3E9197|rigid:8mqY8v0PpY6DCz23ZJRSsF+OG6o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32445 uniprotkb:P53278 intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322039|imex:IM-14275-740 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome) psi-mi:"MI:0469"(intact) crc64:9F913C2FC9EF6E82 crc64:D482327C9274C026 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292 intact-crc:8F48B8D646B8CCA4|rigid:QzvLMSL1up7erXSHDVOH318KHaA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32445 uniprotkb:P53283 intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322050|imex:IM-14275-741 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:9F913C2FC9EF6E82 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 intact-crc:7E281BE5C4D0B397|rigid:FvN07sAYpy6zRVzct2fKQCZB1M4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53829 uniprotkb:P32445 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322061|imex:IM-14275-742 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 psi-mi:"MI:0469"(intact) crc64:F3DBABE6AD3C7F3C crc64:9F913C2FC9EF6E82 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 intact-crc:70F8AC6D9283D39D|rigid:LlyDc1cIkggynzmcx+JPnNnE4bM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32445 uniprotkb:Q02785 intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322072|imex:IM-14275-743 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) crc64:9F913C2FC9EF6E82 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:37D5FC98F65E7CD8|rigid:xcC2bcGdhHLPXkd/OsdyDF8pyPY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32445 uniprotkb:Q03640 intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322083|imex:IM-14275-744 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) crc64:9F913C2FC9EF6E82 crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:79E5F9B55FEE2B85|rigid:t/qDouGV1Dem67PnBm3ZSZ9hE3Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32445 uniprotkb:Q06170 intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A intact:EBI-35994|uniprotkb:D6VYW8|ensemblfungi:YLR326W psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:yl326_yeast(display_long)|uniprotkb:YLR326W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322094|imex:IM-14275-745 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 refseq:NP_013430.1|sgd:S000004318|mint:Q06170|dip:DIP-3995N|ensemblfungi:YLR326W(gene)|ensemblfungi:YLR326W_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR025187 psi-mi:"MI:0469"(intact) crc64:9F913C2FC9EF6E82 crc64:724CD7833AA9B416 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 rogid:Ufkoj1kRp4Y9JTsgbL+3k8hzJyo559292 intact-crc:17F1B8A659557018|rigid:MWnEmjyV15sdIP0R5aoMwVT/6OQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06689 uniprotkb:P32445 intact:EBI-38659|uniprotkb:D6VZ50|ensemblfungi:YLR413W intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A psi-mi:yl413_yeast(display_long)|uniprotkb:YLR413W(locus name) psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322105|imex:IM-14275-746 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013517.1|sgd:S000004405|mint:Q06689|dip:DIP-5075N|ensemblfungi:YLR413W(gene)|ensemblfungi:YLR413W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0071944"(cell periphery)|interpro:IPR009571(SUR7) refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 psi-mi:"MI:0469"(intact) crc64:92E23436DC857E95 crc64:9F913C2FC9EF6E82 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AoTGKjLhw0NECrtuftZqLANonds559292 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 intact-crc:A55593F6A1274A4F|rigid:RSp0avGu48ktzMNdmj1La3EgWw4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32445 uniprotkb:Q07651 intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322116|imex:IM-14275-747 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) crc64:9F913C2FC9EF6E82 - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:39F38D86B8131918|rigid:OaktVyHFkl8q1BwkOR2+xbweAaE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12514 uniprotkb:P32445 intact:EBI-12184|uniprotkb:D6W476|ensemblfungi:YPR072W intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A psi-mi:not5_yeast(display_long)|uniprotkb:NOT5(gene name)|psi-mi:NOT5(display_short)|uniprotkb:YP9499.27(orf name)|uniprotkb:YPR072W(locus name) psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322138|imex:IM-14275-749 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPR072W(gene)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|rcsb pdb:6TB3|ensemblfungi:YPR072W_mRNA(transcript)|refseq:NP_015397.1|sgd:S000006276|dip:DIP-2257N|mint:Q12514 refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 psi-mi:"MI:0469"(intact) crc64:073137119B3E92BC crc64:9F913C2FC9EF6E82 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+XON8Ps4xCFhw058U9d2voUy2dc559292 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 intact-crc:FC8386CF8D5534EE|rigid:6sHWUBxSCIT/gw6X8OhWk+Al3EA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32445 uniprotkb:Q12256 intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322127|imex:IM-14275-748 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:9F913C2FC9EF6E82 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 intact-crc:CA39EA806FD8A0F3|rigid://atySaY7WBltKmGh+gKdGR7yII false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32448 uniprotkb:P25584 intact:EBI-3009|uniprotkb:D6VRF7|ensemblfungi:YDL197C intact:EBI-21765|uniprotkb:D6VQW1|ensemblfungi:YCL056C psi-mi:asf2_yeast(display_long)|uniprotkb:ASF2(gene name)|psi-mi:ASF2(display_short)|uniprotkb:D1219(orf name)|uniprotkb:YDL197C(locus name) psi-mi:pex34_yeast(display_long)|uniprotkb:YCL056C(locus name)|uniprotkb:YCL56C(orf name)|uniprotkb:YCL433(orf name)|uniprotkb:PEX34(gene name)|psi-mi:PEX34(display_short)|uniprotkb:Peroxin-34(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322149|imex:IM-14275-750 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002356|refseq:NP_010084.1|mint:P32448|ensemblfungi:YDL197C(gene)|ensemblfungi:YDL197C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly) sgd:S000000561|refseq:NP_009875.1|mint:P25584|dip:DIP-2040N|ensemblfungi:YCL056C(gene)|ensemblfungi:YCL056C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization) psi-mi:"MI:0469"(intact) - crc64:6035D449766516A6 figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HMg9KbMjKq5qSELHbZGFGl4xAZU559292 rogid:IGoLOZeCbBNA4w+BG9mC/vxGfqs559292 intact-crc:6271FD019A2134AE|rigid:PJKBiS7AtrW2Cw+kdkVrbNsQKa8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32448 uniprotkb:P53032 intact:EBI-3009|uniprotkb:D6VRF7|ensemblfungi:YDL197C intact:EBI-18586|ensemblfungi:YGL162W|uniprotkb:D6VTY9 psi-mi:asf2_yeast(display_long)|uniprotkb:ASF2(gene name)|psi-mi:ASF2(display_short)|uniprotkb:D1219(orf name)|uniprotkb:YDL197C(locus name) psi-mi:sut1_yeast(display_long)|uniprotkb:SUT1(gene name)|psi-mi:SUT1(display_short)|uniprotkb:G1828(orf name)|uniprotkb:YGL162W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322160|imex:IM-14275-751 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002356|refseq:NP_010084.1|mint:P32448|ensemblfungi:YDL197C(gene)|ensemblfungi:YDL197C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly) ensemblfungi:YGL162W(gene)|ensemblfungi:YGL162W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR036864|refseq:NP_011353.1|sgd:S000003130|dip:DIP-5748N|mint:P53032 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HMg9KbMjKq5qSELHbZGFGl4xAZU559292 rogid:0dfbc9nXW+fJd27Z83OQQBzx+gs559292 intact-crc:6B29D8D60ECA2361|rigid:sGzRDWUtQn5fUf4YRzUIf/OyJq4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32448 uniprotkb:P53379 intact:EBI-3009|uniprotkb:D6VRF7|ensemblfungi:YDL197C intact:EBI-10961|ensemblfungi:YDR144C|uniprotkb:D6VSC7 psi-mi:asf2_yeast(display_long)|uniprotkb:ASF2(gene name)|psi-mi:ASF2(display_short)|uniprotkb:D1219(orf name)|uniprotkb:YDL197C(locus name) psi-mi:mkc7_yeast(display_long)|uniprotkb:MKC7(gene name)|psi-mi:MKC7(display_short)|uniprotkb:Yapsin-2(gene name synonym)|uniprotkb:YPS2(gene name synonym)|uniprotkb:YD2943.03C(orf name)|uniprotkb:YD8358.01C(orf name)|uniprotkb:YDR144C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322171|imex:IM-14275-752 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002356|refseq:NP_010084.1|mint:P32448|ensemblfungi:YDL197C(gene)|ensemblfungi:YDL197C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly) ensemblfungi:YDR144C(gene)|ensemblfungi:YDR144C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR021109|interpro:IPR033121|interpro:IPR033876|refseq:NP_010428.3|sgd:S000002551|mint:P53379|dip:DIP-4585N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HMg9KbMjKq5qSELHbZGFGl4xAZU559292 rogid:nOkqdoNlxLbsq8tcN8Qj8NuQ1YY559292 intact-crc:62A0E9DAC3198C5E|rigid:KUAAZrvnAVpOakXkBcTnlF64/YM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32458 uniprotkb:P23542 intact:EBI-4178|uniprotkb:D6VWP6|ensemblfungi:YJR076C intact:EBI-2002|uniprotkb:D6VY29|ensemblfungi:YLR027C psi-mi:cdc11_yeast(display_long)|uniprotkb:CDC11(gene name)|psi-mi:CDC11(display_short)|uniprotkb:PSL9(gene name synonym)|uniprotkb:YJR076C(locus name)|uniprotkb:J1833(orf name) psi-mi:aatc_yeast(display_long)|uniprotkb:AAT2(gene name)|psi-mi:AAT2(display_short)|uniprotkb:YLR027C(locus name)|uniprotkb:ASP5(gene name synonym)|uniprotkb:L1746(orf name)|uniprotkb:Transaminase A(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322182|imex:IM-14275-753 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012610.1|sgd:S000003837|dip:DIP-1656N|mint:P32458|ensemblfungi:YJR076C(gene)|ensemblfungi:YJR076C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:5AR1 refseq:NP_013127.2|sgd:S000004017|dip:DIP-2897N|mint:P23542|go:"GO:0019266"(asparagine biosynthetic process from oxaloacetate)|go:"GO:0030170"(pyridoxal phosphate binding)|interpro:IPR000796(Aspartate/other aminotransferase)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:1YAA|reactome:R-SCE-70263|reactome:R-SCE-8963693|ensemblfungi:YLR027C(gene)|ensemblfungi:YLR027C_mRNA(transcript)|go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0006532"(aspartate biosynthetic process)|go:"GO:0006536"(glutamate metabolic process) psi-mi:"MI:0469"(intact) crc64:5CFFD4CD1F6C57D4 crc64:D25F40F6C6DD2B33 figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:KRcNMx6EOTmvHb+6u15UrVoyb3s559292 rogid:eNypS723YWwMMuWVVoTnidvQuaA559292 intact-crc:1FA4219705BFA050|rigid:inLjYG19qCN18ocbg2EawL+pQVo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25623 uniprotkb:P32458 intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C intact:EBI-4178|uniprotkb:D6VWP6|ensemblfungi:YJR076C psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:cdc11_yeast(display_long)|uniprotkb:CDC11(gene name)|psi-mi:CDC11(display_short)|uniprotkb:PSL9(gene name synonym)|uniprotkb:YJR076C(locus name)|uniprotkb:J1833(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322193|imex:IM-14275-754 author score:99.24 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 refseq:NP_012610.1|sgd:S000003837|dip:DIP-1656N|mint:P32458|ensemblfungi:YJR076C(gene)|ensemblfungi:YJR076C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:5AR1 psi-mi:"MI:0469"(intact) crc64:6F35C8F1562E41CC crc64:5CFFD4CD1F6C57D4 figure legend:tables S3 and S4|author-confidence:99.24|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 rogid:KRcNMx6EOTmvHb+6u15UrVoyb3s559292 intact-crc:32D45065A344F146|rigid:RRAGy44KFkpw+/vdOiqe5RQ+QrA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32458 uniprotkb:P32458 intact:EBI-4178|uniprotkb:D6VWP6|ensemblfungi:YJR076C intact:EBI-4178|uniprotkb:D6VWP6|ensemblfungi:YJR076C psi-mi:cdc11_yeast(display_long)|uniprotkb:CDC11(gene name)|psi-mi:CDC11(display_short)|uniprotkb:PSL9(gene name synonym)|uniprotkb:YJR076C(locus name)|uniprotkb:J1833(orf name) psi-mi:cdc11_yeast(display_long)|uniprotkb:CDC11(gene name)|psi-mi:CDC11(display_short)|uniprotkb:PSL9(gene name synonym)|uniprotkb:YJR076C(locus name)|uniprotkb:J1833(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322204|imex:IM-14275-755 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012610.1|sgd:S000003837|dip:DIP-1656N|mint:P32458|ensemblfungi:YJR076C(gene)|ensemblfungi:YJR076C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:5AR1 refseq:NP_012610.1|sgd:S000003837|dip:DIP-1656N|mint:P32458|ensemblfungi:YJR076C(gene)|ensemblfungi:YJR076C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:5AR1 psi-mi:"MI:0469"(intact) crc64:5CFFD4CD1F6C57D4 crc64:5CFFD4CD1F6C57D4 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:KRcNMx6EOTmvHb+6u15UrVoyb3s559292 rogid:KRcNMx6EOTmvHb+6u15UrVoyb3s559292 intact-crc:87AFD9DDEF54A612|rigid:wS7HcNF/LmWbqRyTpc8l8Ie44AA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07657 uniprotkb:P32458 intact:EBI-22083|uniprotkb:D6VRD0|ensemblfungi:YDL225W intact:EBI-4178|uniprotkb:D6VWP6|ensemblfungi:YJR076C psi-mi:shs1_yeast(display_long)|uniprotkb:YDL225W(locus name)|uniprotkb:Septation protein 7(gene name synonym)|uniprotkb:SHS1(gene name)|psi-mi:SHS1(display_short)|uniprotkb:SEP7(gene name synonym) psi-mi:cdc11_yeast(display_long)|uniprotkb:CDC11(gene name)|psi-mi:CDC11(display_short)|uniprotkb:PSL9(gene name synonym)|uniprotkb:YJR076C(locus name)|uniprotkb:J1833(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322215|imex:IM-14275-756 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010056.1|sgd:S000002384|dip:DIP-5596N|ensemblfungi:YDL225W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010458"(exit from mitosis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043332"(mating projection tip)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061163"(endoplasmic reticulum polarization)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097271"(protein localization to bud neck)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|ensemblfungi:YDL225W(gene)|mint:Q07657 refseq:NP_012610.1|sgd:S000003837|dip:DIP-1656N|mint:P32458|ensemblfungi:YJR076C(gene)|ensemblfungi:YJR076C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:5AR1 psi-mi:"MI:0469"(intact) crc64:BDA2631061A278F9 crc64:5CFFD4CD1F6C57D4 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4A/dWGsbB5nAWr1kP+zTlT9B3z4559292 rogid:KRcNMx6EOTmvHb+6u15UrVoyb3s559292 intact-crc:7A093401C3C49E20|rigid:P7mOcjYUSz4i2d3jDVr4DXrBY10 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32461 uniprotkb:P32324 intact:EBI-6090|uniprotkb:D6VX09|ensemblfungi:YKL191W intact:EBI-6333|uniprotkb:Q6JEF7|uniprotkb:D6VT19|ensemblfungi:YDR385W|ensemblfungi:YOR133W psi-mi:dph2_yeast(display_long)|uniprotkb:DPH2(gene name)|psi-mi:DPH2(display_short)|uniprotkb:Diphtheria toxin resistance protein 2(gene name synonym)|uniprotkb:Diphthamide biosynthesis protein 2(gene name synonym)|uniprotkb:"S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2"(gene name synonym)|uniprotkb:YKL191W(locus name) psi-mi:ef2_yeast(display_long)|uniprotkb:EFT1(gene name)|psi-mi:EFT1(display_short)|uniprotkb:YOR133W(locus name)|uniprotkb:O3317(orf name)|uniprotkb:YOR3317W(orf name)|uniprotkb:EFT2(gene name)|psi-mi:EFT2(display_short)|uniprotkb:YDR385W(locus name)|uniprotkb:Translation elongation factor 2(gene name synonym)|uniprotkb:Eukaryotic elongation factor 2(gene name synonym)|uniprotkb:Ribosomal translocase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322226|imex:IM-14275-757 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012730.1|sgd:S000001674|dip:DIP-5654N|mint:P32461|ensemblfungi:YKL191W(gene)|ensemblfungi:YKL191W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|go:"GO:0090560"("2-(3-amino-3-carboxypropyl)histidine synthase activity")|interpro:IPR010014(Diphthamide synthesis, DHP2)|interpro:IPR016435(Diphthamide synthesis, DHP1)|interpro:IPR042263|interpro:IPR042265|reactome:R-SCE-5358493 refseq:NP_010673.1|refseq:NP_014776.1|sgd:S000005659|sgd:S000002793|ensemblfungi:YDR385W(gene)|ensemblfungi:YDR385W_mRNA(transcript)|ensemblfungi:YOR133W(gene)|ensemblfungi:YOR133W_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0019843"(rRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0051087"(chaperone binding)|go:"GO:1990145"(maintenance of translational fidelity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|mint:P32324|dip:DIP-4911N|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|rcsb pdb:1N0U|rcsb pdb:1N0V|rcsb pdb:1U2R|rcsb pdb:1ZM2|rcsb pdb:1ZM3|rcsb pdb:1ZM4|rcsb pdb:1ZM9|rcsb pdb:2E1R|rcsb pdb:2NPF|rcsb pdb:2P8W|rcsb pdb:2P8X|rcsb pdb:2P8Y|rcsb pdb:2P8Z|rcsb pdb:2ZIT|rcsb pdb:3B78|rcsb pdb:3B82|rcsb pdb:3B8H|rcsb pdb:3DNY|rcsb pdb:4V4B|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|reactome:R-SCE-156902|reactome:R-SCE-5358493|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:FD2F8073CB9B66AA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IdPjtZdDq1ct4EpJ32a6GNYGwPw559292 rogid:mlyt9YKZrGhGbsSlvxNJ0p1C67I559292 intact-crc:EF549DD89006DF30|rigid:Mq+7GGtIUXY5c1lqfp1Mq8wMuj4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:P11076 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322237|imex:IM-14275-758 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 psi-mi:"MI:0469"(intact) - crc64:796859026AC63CC0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 intact-crc:5B1CDE34A961C35A|rigid:qVxhnHVy8S3Uxpdd40BaQ4QH4Yg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:P19807 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322248|imex:IM-14275-759 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:EEB7AD380B0FF9F6|rigid:op4fO/WvIbO0yPsUNcx2hY+2iaE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23585 uniprotkb:P32465 intact:EBI-2054100|uniprotkb:D6VZI5|ensemblfungi:YMR011W intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 psi-mi:hxt2_yeast(display_long)|uniprotkb:YM8270.15(orf name)|uniprotkb:YMR011W(locus name)|uniprotkb:HXT2(gene name)|psi-mi:HXT2(display_short) psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322259|imex:IM-14275-760 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013724.1|sgd:S000004613|dip:DIP-7912N|mint:P23585|ensemblfungi:YMR011W(gene)|ensemblfungi:YMR011W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:d4PFyh6BHnB/WnnF3A4GF3EphgY559292 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 intact-crc:415AE41AF7248A7F|rigid:1pEnLDle6gavkGi+uFnz+VY/jVg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:P32465 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322270|imex:IM-14275-761 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 intact-crc:74796C7CB629DEA2|rigid:g5kKg0kKuyk5gVWf5yFZLzvC4uE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32568 uniprotkb:P32465 intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322281|imex:IM-14275-762 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 intact-crc:D7BF9A3A28A82EF6|rigid:t4UNcWKaWkPj7siZn/VdRSS/qTU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:P33302 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-13038|uniprotkb:D6W2L0|ensemblfungi:YOR153W psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:pdr5_yeast(display_long)|uniprotkb:PDR5(gene name)|psi-mi:PDR5(display_short)|uniprotkb:LEM1(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 5(gene name synonym)|uniprotkb:Suppressor of toxicity of sporidesmin(gene name synonym)|uniprotkb:YOR153W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322292|imex:IM-14275-763 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N sgd:S000005679|refseq:NP_014796.3|mint:P33302|dip:DIP-6776N|ensemblfungi:YOR153W(gene)|ensemblfungi:YOR153W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR029481|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:Sd6SJWf6B0rDZnLVaPHyvr4lhew559292 intact-crc:0E9E04C413C1A321|rigid:1YroaIquMwzROGoMXvuZpof+9rw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:P36027 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322303|imex:IM-14275-764 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:6DCF72F6A5C2BC34|rigid:s3D1+wjVX88yl0Tz2I4lOzPl+3A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38084 uniprotkb:P32465 intact:EBI-3414|uniprotkb:D6VQ67|ensemblfungi:YBR068C intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 psi-mi:bap2_yeast(display_long)|uniprotkb:Branched-chain amino-acid permease 2(gene name synonym)|uniprotkb:BAP2(gene name)|psi-mi:BAP2(display_short)|uniprotkb:YBR068C(locus name)|uniprotkb:YBR0629(orf name) psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322314|imex:IM-14275-765 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000272|refseq:NP_009624.4|dip:DIP-4910N|mint:P38084|ensemblfungi:YBR068C(gene)|ensemblfungi:YBR068C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015192"(L-phenylalanine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098713"(leucine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N psi-mi:"MI:0469"(intact) crc64:B87FD6A7464E07F5 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:7Fw7+M5mBikZBztHE2tSDpvBi/M559292 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 intact-crc:B93D6F9FE0F9F174|rigid:2bySjv1UyREoKxA6yuTF5DVsXT4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:P38234 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322325|imex:IM-14275-766 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 intact-crc:3E82D3A9ADF4048C|rigid:LE5zDNzKx+ZpYb3LlEuxQ3Gqm6U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:P39968 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322336|imex:IM-14275-767 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N psi-mi:"MI:0469"(intact) - crc64:B2E75774B47E5933 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292 intact-crc:FD4805AB5665CDC4|rigid:B+kXfN5yFrGFbyO+7R9yPj3k4ks false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:P40474 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322347|imex:IM-14275-768 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 intact-crc:806D972851E10911|rigid:mGugZ/ZXVZAzBSIUJPD/32vxC+0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:P50276 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322358|imex:IM-14275-769 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:8D1528D3774462A7|rigid:1ngez3YPPHHFVs/eupCL8CvIc8Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53283 uniprotkb:P32465 intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322369|imex:IM-14275-770 author score:83.40 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:83.40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 intact-crc:A0EA1D25C34BF0A7|rigid:u7jEPM32V8IpYlzT1htlf88byuA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:P53388 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322380|imex:IM-14275-771 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) psi-mi:"MI:0469"(intact) - crc64:488A382656039D0B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 intact-crc:22B8000787327509|rigid:B1I51L+bDyUkFCUovafhWIvjlZg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:Q02785 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322391|imex:IM-14275-772 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:E917FC98FF248FE8|rigid:bX06twPRtRFK6pkuWCPMBymcbSg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:P32465 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322402|imex:IM-14275-773 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 intact-crc:A727F9B55694D8B5|rigid:1jsXXDAd5ZmCTaJfGJQT4TOPS5g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06451 uniprotkb:P32465 intact:EBI-34275|uniprotkb:D6W4F2|ensemblfungi:YPR156C intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 psi-mi:tpo3_yeast(display_long)|uniprotkb:TPO3(gene name)|psi-mi:TPO3(display_short)|uniprotkb:P9584.7(orf name)|uniprotkb:YPR156C(locus name) psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322413|imex:IM-14275-774 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015482.1|sgd:S000006360|mint:Q06451|dip:DIP-3907N|ensemblfungi:YPR156C(gene)|ensemblfungi:YPR156C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N psi-mi:"MI:0469"(intact) crc64:D260ED161F800502 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oVpx7Bjk/mK2Q7+/j05tX3gHw7k559292 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 intact-crc:8621E0CB1E2E87E5|rigid:fzOecA2FwZMc9nS0jxQ7r97LMUo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32469 uniprotkb:P32324 intact:EBI-6095|uniprotkb:Q6Q5L4|uniprotkb:D6VYH6|ensemblfungi:YLR172C intact:EBI-6333|uniprotkb:Q6JEF7|uniprotkb:D6VT19|ensemblfungi:YDR385W|ensemblfungi:YOR133W psi-mi:dph5_yeast(display_long)|uniprotkb:DPH5(gene name)|psi-mi:DPH5(display_short)|uniprotkb:YLR172C(locus name)|uniprotkb:L9470.17(orf name)|uniprotkb:Diphthamide biosynthesis methyltransferase(gene name synonym) psi-mi:ef2_yeast(display_long)|uniprotkb:EFT1(gene name)|psi-mi:EFT1(display_short)|uniprotkb:YOR133W(locus name)|uniprotkb:O3317(orf name)|uniprotkb:YOR3317W(orf name)|uniprotkb:EFT2(gene name)|psi-mi:EFT2(display_short)|uniprotkb:YDR385W(locus name)|uniprotkb:Translation elongation factor 2(gene name synonym)|uniprotkb:Eukaryotic elongation factor 2(gene name synonym)|uniprotkb:Ribosomal translocase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322424|imex:IM-14275-775 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013273.1|sgd:S000004162|dip:DIP-4237N|mint:P32469|ensemblfungi:YLR172C(gene)|ensemblfungi:YLR172C_mRNA(transcript)|go:"GO:0004164"(diphthine synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|go:"GO:0032259"(methylation)|interpro:IPR000878(Tetrapyrrole methylase)|interpro:IPR004551(Diphthine synthase)|interpro:IPR014776(Tetrapyrrole methylase, subdomain 2)|interpro:IPR014777(Tetrapyrrole methylase, subdomain 1)|interpro:IPR035996|reactome:R-SCE-5358493 refseq:NP_010673.1|refseq:NP_014776.1|sgd:S000005659|sgd:S000002793|ensemblfungi:YDR385W(gene)|ensemblfungi:YDR385W_mRNA(transcript)|ensemblfungi:YOR133W(gene)|ensemblfungi:YOR133W_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0019843"(rRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0051087"(chaperone binding)|go:"GO:1990145"(maintenance of translational fidelity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|mint:P32324|dip:DIP-4911N|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|rcsb pdb:1N0U|rcsb pdb:1N0V|rcsb pdb:1U2R|rcsb pdb:1ZM2|rcsb pdb:1ZM3|rcsb pdb:1ZM4|rcsb pdb:1ZM9|rcsb pdb:2E1R|rcsb pdb:2NPF|rcsb pdb:2P8W|rcsb pdb:2P8X|rcsb pdb:2P8Y|rcsb pdb:2P8Z|rcsb pdb:2ZIT|rcsb pdb:3B78|rcsb pdb:3B82|rcsb pdb:3B8H|rcsb pdb:3DNY|rcsb pdb:4V4B|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|reactome:R-SCE-156902|reactome:R-SCE-5358493|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:FD2F8073CB9B66AA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:s9m/xoFa8RJrA9BBJ/RU7UyIvdE559292 rogid:mlyt9YKZrGhGbsSlvxNJ0p1C67I559292 intact-crc:029CC4E9BFA42D97|rigid:JNJZF0Q43NEE3mmIyptgXjpOpIY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32469 uniprotkb:P32469 intact:EBI-6095|uniprotkb:Q6Q5L4|uniprotkb:D6VYH6|ensemblfungi:YLR172C intact:EBI-6095|uniprotkb:Q6Q5L4|uniprotkb:D6VYH6|ensemblfungi:YLR172C psi-mi:dph5_yeast(display_long)|uniprotkb:DPH5(gene name)|psi-mi:DPH5(display_short)|uniprotkb:YLR172C(locus name)|uniprotkb:L9470.17(orf name)|uniprotkb:Diphthamide biosynthesis methyltransferase(gene name synonym) psi-mi:dph5_yeast(display_long)|uniprotkb:DPH5(gene name)|psi-mi:DPH5(display_short)|uniprotkb:YLR172C(locus name)|uniprotkb:L9470.17(orf name)|uniprotkb:Diphthamide biosynthesis methyltransferase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322435|imex:IM-14275-776 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013273.1|sgd:S000004162|dip:DIP-4237N|mint:P32469|ensemblfungi:YLR172C(gene)|ensemblfungi:YLR172C_mRNA(transcript)|go:"GO:0004164"(diphthine synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|go:"GO:0032259"(methylation)|interpro:IPR000878(Tetrapyrrole methylase)|interpro:IPR004551(Diphthine synthase)|interpro:IPR014776(Tetrapyrrole methylase, subdomain 2)|interpro:IPR014777(Tetrapyrrole methylase, subdomain 1)|interpro:IPR035996|reactome:R-SCE-5358493 refseq:NP_013273.1|sgd:S000004162|dip:DIP-4237N|mint:P32469|ensemblfungi:YLR172C(gene)|ensemblfungi:YLR172C_mRNA(transcript)|go:"GO:0004164"(diphthine synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|go:"GO:0032259"(methylation)|interpro:IPR000878(Tetrapyrrole methylase)|interpro:IPR004551(Diphthine synthase)|interpro:IPR014776(Tetrapyrrole methylase, subdomain 2)|interpro:IPR014777(Tetrapyrrole methylase, subdomain 1)|interpro:IPR035996|reactome:R-SCE-5358493 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:s9m/xoFa8RJrA9BBJ/RU7UyIvdE559292 rogid:s9m/xoFa8RJrA9BBJ/RU7UyIvdE559292 intact-crc:3B5519E21070F64E|rigid:zVBeefnhpPoMYN5q8uM9st7rzVU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32485 uniprotkb:P38623 intact:EBI-8437|uniprotkb:Q06232|uniprotkb:Q12294|uniprotkb:D6VYB1|ensemblfungi:YLR113W intact:EBI-14885|uniprotkb:Q02532|uniprotkb:Q06557|uniprotkb:D6VYP6|ensemblfungi:YLR248W psi-mi:hog1_yeast(display_long)|uniprotkb:HOG1(gene name)|psi-mi:HOG1(display_short)|uniprotkb:SSK3(gene name synonym)|uniprotkb:YLR113W(locus name)|uniprotkb:L2931(orf name)|uniprotkb:L9354.2(orf name)|uniprotkb:High osmolarity glycerol response protein 1(gene name synonym) psi-mi:rck2_yeast(display_long)|uniprotkb:RCK2(gene name)|psi-mi:RCK2(display_short)|uniprotkb:CLK1(gene name synonym)|uniprotkb:CMK3(gene name synonym)|uniprotkb:YLR248W(locus name)|uniprotkb:L9672.6(orf name)|uniprotkb:CAM kinase-like protein kinase CLK1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322446|imex:IM-14275-777 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013214.1|sgd:S000004103|dip:DIP-1558N|mint:P32485|ensemblfungi:YLR113W_mRNA(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR038783|reactome:R-SCE-168638|reactome:R-SCE-193648|reactome:R-SCE-198753|reactome:R-SCE-2559580|reactome:R-SCE-2871796|reactome:R-SCE-418592|reactome:R-SCE-432142|reactome:R-SCE-450321|reactome:R-SCE-450341|reactome:R-SCE-525793|reactome:R-SCE-6798695|reactome:R-SCE-9007892|ensemblfungi:YLR113W(gene) refseq:NP_013349.1|sgd:S000004238|ensemblfungi:YLR248W(gene)|ensemblfungi:YLR248W_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-9619229|dip:DIP-5079N|mint:P38623 psi-mi:"MI:0469"(intact) crc64:D95A20242587CE06 crc64:00DDC674F6723E6A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Re8xLAJEvP2Fjr0lOGtLB6ANybM559292 rogid:4VUkn/0mqnutY8hSJdNTA3ZyPeY559292 intact-crc:74F925B460E0253E|rigid:LsBCzV7RsEMf7e8oLNLhZiiJsDE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32492 uniprotkb:P32492 intact:EBI-11681|ensemblfungi:YAL029C|uniprotkb:D6VPI9 intact:EBI-11681|ensemblfungi:YAL029C|uniprotkb:D6VPI9 psi-mi:myo4_yeast(display_long)|uniprotkb:MYO4(gene name)|psi-mi:MYO4(display_short)|uniprotkb:SHE1(gene name synonym)|uniprotkb:YAL029C(locus name)|uniprotkb:FUN22(orf name)|uniprotkb:SWI5-dependent HO expression protein 1(gene name synonym) psi-mi:myo4_yeast(display_long)|uniprotkb:MYO4(gene name)|psi-mi:MYO4(display_short)|uniprotkb:SHE1(gene name synonym)|uniprotkb:YAL029C(locus name)|uniprotkb:FUN22(orf name)|uniprotkb:SWI5-dependent HO expression protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322457|imex:IM-14275-778 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007015"(actin filament organization)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002710(Dilute)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036103|interpro:IPR036961|rcsb pdb:3MMI|rcsb pdb:4LL6|rcsb pdb:4LL8|reactome:R-SCE-190873|reactome:R-SCE-9013419|reactome:R-SCE-9013425|ensemblfungi:YAL029C(gene)|ensemblfungi:YAL029C_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|refseq:NP_009373.1|sgd:S000000027|mint:P32492|dip:DIP-5761N go:"GO:0007015"(actin filament organization)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002710(Dilute)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036103|interpro:IPR036961|rcsb pdb:3MMI|rcsb pdb:4LL6|rcsb pdb:4LL8|reactome:R-SCE-190873|reactome:R-SCE-9013419|reactome:R-SCE-9013425|ensemblfungi:YAL029C(gene)|ensemblfungi:YAL029C_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|refseq:NP_009373.1|sgd:S000000027|mint:P32492|dip:DIP-5761N psi-mi:"MI:0469"(intact) crc64:E79C0FE72B041E95 crc64:E79C0FE72B041E95 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jxx/cStiu7zpcGFLmoTedhHVZcY559292 rogid:jxx/cStiu7zpcGFLmoTedhHVZcY559292 intact-crc:661ABAF9848743A0|rigid:DhDdcgIAIQyCRRKyX2n5HpqKZbU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36068 uniprotkb:P32492 intact:EBI-26866|uniprotkb:D6VX65|ensemblfungi:YKL130C intact:EBI-11681|ensemblfungi:YAL029C|uniprotkb:D6VPI9 psi-mi:she2_yeast(display_long)|uniprotkb:YKL130C(locus name)|uniprotkb:SHE2(gene name)|psi-mi:SHE2(display_short) psi-mi:myo4_yeast(display_long)|uniprotkb:MYO4(gene name)|psi-mi:MYO4(display_short)|uniprotkb:SHE1(gene name synonym)|uniprotkb:YAL029C(locus name)|uniprotkb:FUN22(orf name)|uniprotkb:SWI5-dependent HO expression protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322468|imex:IM-14275-779 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012792.1|sgd:S000001613|mint:P36068|dip:DIP-1206N|ensemblfungi:YKL130C(gene)|ensemblfungi:YKL130C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005934"(cellular bud tip)|go:"GO:0007533"(mating type switching)|go:"GO:0008289"(lipid binding)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0051028"(mRNA transport)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR024261|interpro:IPR036827|rcsb pdb:1XLY|rcsb pdb:4WNL|rcsb pdb:5M0I|rcsb pdb:5M0J go:"GO:0007015"(actin filament organization)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002710(Dilute)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036103|interpro:IPR036961|rcsb pdb:3MMI|rcsb pdb:4LL6|rcsb pdb:4LL8|reactome:R-SCE-190873|reactome:R-SCE-9013419|reactome:R-SCE-9013425|ensemblfungi:YAL029C(gene)|ensemblfungi:YAL029C_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|refseq:NP_009373.1|sgd:S000000027|mint:P32492|dip:DIP-5761N psi-mi:"MI:0469"(intact) crc64:5514B374655EFDBB crc64:E79C0FE72B041E95 figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UkbzQaIhI+P2wZVxpnoMFUj0gGo559292 rogid:jxx/cStiu7zpcGFLmoTedhHVZcY559292 intact-crc:EB79FD66EA1F6D81|rigid:UmK6DGq5tW/E6sLkQQiTSVmQELE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32492 uniprotkb:P38272 intact:EBI-11681|ensemblfungi:YAL029C|uniprotkb:D6VPI9 intact:EBI-21600|uniprotkb:D6VQC7|ensemblfungi:YBR130C psi-mi:myo4_yeast(display_long)|uniprotkb:MYO4(gene name)|psi-mi:MYO4(display_short)|uniprotkb:SHE1(gene name synonym)|uniprotkb:YAL029C(locus name)|uniprotkb:FUN22(orf name)|uniprotkb:SWI5-dependent HO expression protein 1(gene name synonym) psi-mi:she3_yeast(display_long)|uniprotkb:YBR1005(orf name)|uniprotkb:YBR130C(locus name)|uniprotkb:SHE3(gene name)|psi-mi:SHE3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322479|imex:IM-14275-780 author score:99.24 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007015"(actin filament organization)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002710(Dilute)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036103|interpro:IPR036961|rcsb pdb:3MMI|rcsb pdb:4LL6|rcsb pdb:4LL8|reactome:R-SCE-190873|reactome:R-SCE-9013419|reactome:R-SCE-9013425|ensemblfungi:YAL029C(gene)|ensemblfungi:YAL029C_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|refseq:NP_009373.1|sgd:S000000027|mint:P32492|dip:DIP-5761N sgd:S000000334|refseq:NP_009688.3|mint:P38272|dip:DIP-2037N|ensemblfungi:YBR130C(gene)|ensemblfungi:YBR130C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0051028"(mRNA transport)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR031398|rcsb pdb:4LL7|rcsb pdb:4LL8|rcsb pdb:4WNL|rcsb pdb:5M0I|rcsb pdb:5M0J psi-mi:"MI:0469"(intact) crc64:E79C0FE72B041E95 crc64:590404D2E140BB7A figure legend:tables S3 and S4|author-confidence:99.24|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jxx/cStiu7zpcGFLmoTedhHVZcY559292 rogid:HmP1/ozLaDCRVBA9eJ10x7CYNjI559292 intact-crc:CA43CE2EE1EF79CA|rigid:eeZUdGg1c631m7Ik/dqUfpLlR5g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32499 uniprotkb:P14907 intact:EBI-12401|uniprotkb:Q06130|ensemblfungi:YLR335W|uniprotkb:D6VYX5 intact:EBI-12265|uniprotkb:D6VWE3 psi-mi:nup2_yeast(display_long)|uniprotkb:NUP2(gene name)|psi-mi:NUP2(display_short)|uniprotkb:YLR335W(locus name)|uniprotkb:L8300.9(orf name)|uniprotkb:Nuclear pore protein NUP2(gene name synonym)|uniprotkb:p95(gene name synonym) psi-mi:nsp1_yeast(display_long)|uniprotkb:NSP1(gene name)|psi-mi:NSP1(display_short)|uniprotkb:YJL041W(locus name)|uniprotkb:J1207(orf name)|uniprotkb:Nuclear pore protein NSP1(gene name synonym)|uniprotkb:Nucleoskeletal-like protein(gene name synonym)|uniprotkb:p110(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322490|imex:IM-14275-781 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013439.1|sgd:S000004327|ensemblfungi:YLR335W(gene)|ensemblfungi:YLR335W_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061676"(importin-alpha family protein binding)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015007("NUP50 (Nucleoporin 50 kDa)")|rcsb pdb:1UN0|rcsb pdb:2C1T|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|mint:P32499|dip:DIP-859N go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0097064"(ncRNA export from nucleus)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|rcsb pdb:1O6O|refseq:NP_012494.3|sgd:S000003577|mint:P14907|dip:DIP-1484N psi-mi:"MI:0469"(intact) crc64:467210F14FA73311 crc64:A258003CB1917810 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:n0JzHu75yD2leLZP5A5pkbeEXXI559292 rogid:wFdC6D8JzkhJpF+k3qtnFj9+4pA559292 intact-crc:1AE5771470AE93B1|rigid:dmYDwY+uP+XAne07aL87w5Q9JoM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32499 uniprotkb:P34077 intact:EBI-12401|uniprotkb:Q06130|ensemblfungi:YLR335W|uniprotkb:D6VYX5 intact:EBI-12056|ensemblfungi:YFR002W|uniprotkb:D6VTN2 psi-mi:nup2_yeast(display_long)|uniprotkb:NUP2(gene name)|psi-mi:NUP2(display_short)|uniprotkb:YLR335W(locus name)|uniprotkb:L8300.9(orf name)|uniprotkb:Nuclear pore protein NUP2(gene name synonym)|uniprotkb:p95(gene name synonym) psi-mi:nic96_yeast(display_long)|uniprotkb:YFR002W(locus name)|uniprotkb:NIC96(gene name)|psi-mi:NIC96(display_short)|uniprotkb:Nuclear pore protein NIC96(gene name synonym)|uniprotkb:96 kDa nucleoporin-interacting component(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322501|imex:IM-14275-782 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013439.1|sgd:S000004327|ensemblfungi:YLR335W(gene)|ensemblfungi:YLR335W_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061676"(importin-alpha family protein binding)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015007("NUP50 (Nucleoporin 50 kDa)")|rcsb pdb:1UN0|rcsb pdb:2C1T|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|mint:P32499|dip:DIP-859N ensemblfungi:YFR002W(gene)|ensemblfungi:YFR002W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044615"(nuclear pore nuclear basket)|interpro:IPR007231(Nucleoporin interacting component)|rcsb pdb:2RFO|rcsb pdb:6X07|rcsb pdb:2QX5|refseq:NP_116657.1|sgd:S000001898|mint:P34077|dip:DIP-745N psi-mi:"MI:0469"(intact) crc64:467210F14FA73311 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:n0JzHu75yD2leLZP5A5pkbeEXXI559292 rogid:gjcrAg3tofVODSE7T+SsoTVlesA559292 intact-crc:4DBD5A2945B5D64B|rigid:qP1rSWJFvlL4NF0I644jd54yWgk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32499 uniprotkb:P47054 intact:EBI-12401|uniprotkb:Q06130|ensemblfungi:YLR335W|uniprotkb:D6VYX5 intact:EBI-25846|uniprotkb:D6VWE4|ensemblfungi:YJL039C psi-mi:nup2_yeast(display_long)|uniprotkb:NUP2(gene name)|psi-mi:NUP2(display_short)|uniprotkb:YLR335W(locus name)|uniprotkb:L8300.9(orf name)|uniprotkb:Nuclear pore protein NUP2(gene name synonym)|uniprotkb:p95(gene name synonym) psi-mi:nu192_yeast(display_long)|uniprotkb:NUP192(gene name)|psi-mi:NUP192(display_short)|uniprotkb:YJL039C(locus name)|uniprotkb:Nuclear pore protein NUP192(gene name synonym)|uniprotkb:J1216(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322512|imex:IM-14275-783 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013439.1|sgd:S000004327|ensemblfungi:YLR335W(gene)|ensemblfungi:YLR335W_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061676"(importin-alpha family protein binding)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015007("NUP50 (Nucleoporin 50 kDa)")|rcsb pdb:1UN0|rcsb pdb:2C1T|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|mint:P32499|dip:DIP-859N refseq:NP_012495.1|sgd:S000003576|mint:P47054|dip:DIP-2442N|ensemblfungi:YJL039C(gene)|ensemblfungi:YJL039C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051028"(mRNA transport)|interpro:IPR021827|rcsb pdb:4IFQ psi-mi:"MI:0469"(intact) crc64:467210F14FA73311 crc64:FD2D61FDEA5451C4 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:n0JzHu75yD2leLZP5A5pkbeEXXI559292 rogid:HHXFbw/lDVgq4gDuRbZO57yxvH8559292 intact-crc:3A86F8D332D08796|rigid:lowAvc6tYCrwCmxO6P5+TM8txEc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32499 uniprotkb:P48837 intact:EBI-12401|uniprotkb:Q06130|ensemblfungi:YLR335W|uniprotkb:D6VYX5 intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0 psi-mi:nup2_yeast(display_long)|uniprotkb:NUP2(gene name)|psi-mi:NUP2(display_short)|uniprotkb:YLR335W(locus name)|uniprotkb:L8300.9(orf name)|uniprotkb:Nuclear pore protein NUP2(gene name synonym)|uniprotkb:p95(gene name synonym) psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322523|imex:IM-14275-784 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013439.1|sgd:S000004327|ensemblfungi:YLR335W(gene)|ensemblfungi:YLR335W_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061676"(importin-alpha family protein binding)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015007("NUP50 (Nucleoporin 50 kDa)")|rcsb pdb:1UN0|rcsb pdb:2C1T|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|mint:P32499|dip:DIP-859N ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N psi-mi:"MI:0469"(intact) crc64:467210F14FA73311 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:n0JzHu75yD2leLZP5A5pkbeEXXI559292 rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292 intact-crc:74C0B0F83649B0DA|rigid:7x2Qu9OJ+125HIzadXi1/gPjAk0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32499 uniprotkb:Q02199 intact:EBI-12401|uniprotkb:Q06130|ensemblfungi:YLR335W|uniprotkb:D6VYX5 intact:EBI-12315|ensemblfungi:YGL172W|uniprotkb:D6VTY0 psi-mi:nup2_yeast(display_long)|uniprotkb:NUP2(gene name)|psi-mi:NUP2(display_short)|uniprotkb:YLR335W(locus name)|uniprotkb:L8300.9(orf name)|uniprotkb:Nuclear pore protein NUP2(gene name synonym)|uniprotkb:p95(gene name synonym) psi-mi:nup49_yeast(display_long)|uniprotkb:NUP49(gene name)|psi-mi:NUP49(display_short)|uniprotkb:NSP49(gene name synonym)|uniprotkb:YGL172W(locus name)|uniprotkb:G1648(orf name)|uniprotkb:Nuclear pore protein NUP49/NSP49(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322534|imex:IM-14275-785 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013439.1|sgd:S000004327|ensemblfungi:YLR335W(gene)|ensemblfungi:YLR335W_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061676"(importin-alpha family protein binding)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015007("NUP50 (Nucleoporin 50 kDa)")|rcsb pdb:1UN0|rcsb pdb:2C1T|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|mint:P32499|dip:DIP-859N refseq:NP_011343.1|sgd:S000003140|ensemblfungi:YGL172W(gene)|ensemblfungi:YGL172W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR024864|interpro:IPR025574|interpro:IPR039079|mint:Q02199|dip:DIP-709N psi-mi:"MI:0469"(intact) crc64:467210F14FA73311 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:n0JzHu75yD2leLZP5A5pkbeEXXI559292 rogid:2x0Rt5ViHxBEKxPzOcfnyOdgmpg559292 intact-crc:C3ACF19B7F552F68|rigid:6IsatAPxsedlO7r89tsxxTun024 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32500 uniprotkb:P06197 intact:EBI-11950|ensemblfungi:YML031W|uniprotkb:D6VZE3 intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W psi-mi:ndc1_yeast(display_long)|uniprotkb:YML031W(locus name)|uniprotkb:NDC1(gene name)|psi-mi:NDC1(display_short)|uniprotkb:Nuclear pore protein NDC1(gene name synonym)|uniprotkb:Nuclear division cycle protein 1(gene name synonym) psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322545|imex:IM-14275-786 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML031W(gene)|ensemblfungi:YML031W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0070631"(spindle pole body localization)|go:"GO:0070762"(nuclear pore transmembrane ring)|go:"GO:0106166"(spindle pole body-nuclear membrane anchor activity)|interpro:IPR019049|go:"GO:0017056"(structural constituent of nuclear pore)|refseq:NP_013681.1|sgd:S000004493|mint:P32500|dip:DIP-1465N refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 psi-mi:"MI:0469"(intact) - crc64:6E2E62252B3CB5E2 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CJawnqL6UYhpSqsKMbif8ifzgUY559292 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 intact-crc:2B34911526A71BF2|rigid:tiA5PZ10yEIGISlsOcZ0NZsFlDc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32500 uniprotkb:P32500 intact:EBI-11950|ensemblfungi:YML031W|uniprotkb:D6VZE3 intact:EBI-11950|ensemblfungi:YML031W|uniprotkb:D6VZE3 psi-mi:ndc1_yeast(display_long)|uniprotkb:YML031W(locus name)|uniprotkb:NDC1(gene name)|psi-mi:NDC1(display_short)|uniprotkb:Nuclear pore protein NDC1(gene name synonym)|uniprotkb:Nuclear division cycle protein 1(gene name synonym) psi-mi:ndc1_yeast(display_long)|uniprotkb:YML031W(locus name)|uniprotkb:NDC1(gene name)|psi-mi:NDC1(display_short)|uniprotkb:Nuclear pore protein NDC1(gene name synonym)|uniprotkb:Nuclear division cycle protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322556|imex:IM-14275-787 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML031W(gene)|ensemblfungi:YML031W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0070631"(spindle pole body localization)|go:"GO:0070762"(nuclear pore transmembrane ring)|go:"GO:0106166"(spindle pole body-nuclear membrane anchor activity)|interpro:IPR019049|go:"GO:0017056"(structural constituent of nuclear pore)|refseq:NP_013681.1|sgd:S000004493|mint:P32500|dip:DIP-1465N ensemblfungi:YML031W(gene)|ensemblfungi:YML031W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0070631"(spindle pole body localization)|go:"GO:0070762"(nuclear pore transmembrane ring)|go:"GO:0106166"(spindle pole body-nuclear membrane anchor activity)|interpro:IPR019049|go:"GO:0017056"(structural constituent of nuclear pore)|refseq:NP_013681.1|sgd:S000004493|mint:P32500|dip:DIP-1465N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CJawnqL6UYhpSqsKMbif8ifzgUY559292 rogid:CJawnqL6UYhpSqsKMbif8ifzgUY559292 intact-crc:B51DE35788E2B4F6|rigid:v5AUyYJ+LlwEDf70aHD+htzk0wQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32500 uniprotkb:P34077 intact:EBI-11950|ensemblfungi:YML031W|uniprotkb:D6VZE3 intact:EBI-12056|ensemblfungi:YFR002W|uniprotkb:D6VTN2 psi-mi:ndc1_yeast(display_long)|uniprotkb:YML031W(locus name)|uniprotkb:NDC1(gene name)|psi-mi:NDC1(display_short)|uniprotkb:Nuclear pore protein NDC1(gene name synonym)|uniprotkb:Nuclear division cycle protein 1(gene name synonym) psi-mi:nic96_yeast(display_long)|uniprotkb:YFR002W(locus name)|uniprotkb:NIC96(gene name)|psi-mi:NIC96(display_short)|uniprotkb:Nuclear pore protein NIC96(gene name synonym)|uniprotkb:96 kDa nucleoporin-interacting component(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322567|imex:IM-14275-788 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML031W(gene)|ensemblfungi:YML031W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0070631"(spindle pole body localization)|go:"GO:0070762"(nuclear pore transmembrane ring)|go:"GO:0106166"(spindle pole body-nuclear membrane anchor activity)|interpro:IPR019049|go:"GO:0017056"(structural constituent of nuclear pore)|refseq:NP_013681.1|sgd:S000004493|mint:P32500|dip:DIP-1465N ensemblfungi:YFR002W(gene)|ensemblfungi:YFR002W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044615"(nuclear pore nuclear basket)|interpro:IPR007231(Nucleoporin interacting component)|rcsb pdb:2RFO|rcsb pdb:6X07|rcsb pdb:2QX5|refseq:NP_116657.1|sgd:S000001898|mint:P34077|dip:DIP-745N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CJawnqL6UYhpSqsKMbif8ifzgUY559292 rogid:gjcrAg3tofVODSE7T+SsoTVlesA559292 intact-crc:FE3B3B083252843A|rigid:ku+eCdTPpqKZ5Uc+wALEa/j/vt8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32500 uniprotkb:P53337 intact:EBI-11950|ensemblfungi:YML031W|uniprotkb:D6VZE3 intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C psi-mi:ndc1_yeast(display_long)|uniprotkb:YML031W(locus name)|uniprotkb:NDC1(gene name)|psi-mi:NDC1(display_short)|uniprotkb:Nuclear pore protein NDC1(gene name synonym)|uniprotkb:Nuclear division cycle protein 1(gene name synonym) psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322578|imex:IM-14275-789 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML031W(gene)|ensemblfungi:YML031W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0070631"(spindle pole body localization)|go:"GO:0070762"(nuclear pore transmembrane ring)|go:"GO:0106166"(spindle pole body-nuclear membrane anchor activity)|interpro:IPR019049|go:"GO:0017056"(structural constituent of nuclear pore)|refseq:NP_013681.1|sgd:S000004493|mint:P32500|dip:DIP-1465N refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CJawnqL6UYhpSqsKMbif8ifzgUY559292 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 intact-crc:10EB0A965908F372|rigid:kwb44agDjVGxs8zSE81kzQK/KBU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32500 uniprotkb:Q05166 intact:EBI-11950|ensemblfungi:YML031W|uniprotkb:D6VZE3 intact:EBI-3035|uniprotkb:Q12456|uniprotkb:E9P903|uniprotkb:D6VRR0|ensemblfungi:YDL088C psi-mi:ndc1_yeast(display_long)|uniprotkb:YML031W(locus name)|uniprotkb:NDC1(gene name)|psi-mi:NDC1(display_short)|uniprotkb:Nuclear pore protein NDC1(gene name synonym)|uniprotkb:Nuclear division cycle protein 1(gene name synonym) psi-mi:nup59_yeast(display_long)|uniprotkb:ASM4(gene name)|psi-mi:ASM4(display_short)|uniprotkb:Nuclear pore protein NUP59(gene name synonym)|uniprotkb:NUP59(gene name synonym)|uniprotkb:D2420(orf name)|uniprotkb:YDL088C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322589|imex:IM-14275-790 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML031W(gene)|ensemblfungi:YML031W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0070631"(spindle pole body localization)|go:"GO:0070762"(nuclear pore transmembrane ring)|go:"GO:0106166"(spindle pole body-nuclear membrane anchor activity)|interpro:IPR019049|go:"GO:0017056"(structural constituent of nuclear pore)|refseq:NP_013681.1|sgd:S000004493|mint:P32500|dip:DIP-1465N refseq:NP_010195.1|sgd:S000002246|dip:DIP-1466N|mint:Q05166|ensemblfungi:YDL088C(gene)|ensemblfungi:YDL088C_mRNA(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007049"(cell cycle)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0051301"(cell division)|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017389(Nucleoporin, NUP53)|interpro:IPR035979 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CJawnqL6UYhpSqsKMbif8ifzgUY559292 rogid:t8/JWDKB0Spe2P8qdZnKs/RB3SY559292 intact-crc:9192A98F323A8980|rigid:ISJRySoF8A4QH55nfl6aOvr1q4E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32500 uniprotkb:Q06144 intact:EBI-11950|ensemblfungi:YML031W|uniprotkb:D6VZE3 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:ndc1_yeast(display_long)|uniprotkb:YML031W(locus name)|uniprotkb:NDC1(gene name)|psi-mi:NDC1(display_short)|uniprotkb:Nuclear pore protein NDC1(gene name synonym)|uniprotkb:Nuclear division cycle protein 1(gene name synonym) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322600|imex:IM-14275-791 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML031W(gene)|ensemblfungi:YML031W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0070631"(spindle pole body localization)|go:"GO:0070762"(nuclear pore transmembrane ring)|go:"GO:0106166"(spindle pole body-nuclear membrane anchor activity)|interpro:IPR019049|go:"GO:0017056"(structural constituent of nuclear pore)|refseq:NP_013681.1|sgd:S000004493|mint:P32500|dip:DIP-1465N refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:2F474503CAB7C195 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CJawnqL6UYhpSqsKMbif8ifzgUY559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 intact-crc:EC9E3E35FE84B7FB|rigid:69cPv8Amx4AOYf2W+JSERA1kADs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32502 uniprotkb:P12754 intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C intact:EBI-6265|uniprotkb:D6VUL5|ensemblfungi:YGR083C psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name) psi-mi:ei2bd_yeast(display_long)|uniprotkb:GCD2(gene name)|psi-mi:GCD2(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym)|uniprotkb:GCD complex subunit GCD2(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD2(gene name synonym)|uniprotkb:TIF224(gene name synonym)|uniprotkb:YGR083C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322611|imex:IM-14275-792 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_011597.1|sgd:S000003315|dip:DIP-2343N|mint:P12754|ensemblfungi:YGR083C(gene)|ensemblfungi:YGR083C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 psi-mi:"MI:0469"(intact) crc64:A5409FAF1594854C crc64:B188457543CE1AAE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292 rogid:q04UNg7w1BfegEmJy01O+BDTJno559292 intact-crc:BFEE30EFFCC0B8DA|rigid:sQGAWFiRp+IEfVwn6Asx2ZEyd8I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32502 uniprotkb:P14741 intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C intact:EBI-6253|uniprotkb:D6VX91|ensemblfungi:YKR026C psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name) psi-mi:ei2ba_yeast(display_long)|uniprotkb:GCN3(gene name)|psi-mi:GCN3(display_short)|uniprotkb:AAS2(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym)|uniprotkb:GCD complex subunit GCN3(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCN3(gene name synonym)|uniprotkb:TIF221(gene name synonym)|uniprotkb:YKR026C(locus name)|uniprotkb:Translational activator GCN3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322622|imex:IM-14275-793 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_012951.1|sgd:S000001734|dip:DIP-1328N|mint:P14741|ensemblfungi:YKR026C(gene)|ensemblfungi:YKR026C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 psi-mi:"MI:0469"(intact) crc64:A5409FAF1594854C crc64:8E9A928D6D56E12B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292 rogid:Nm+Ahop9EG8SQNZbo6+usIB9SAY559292 intact-crc:C98953BFB0E22387|rigid:hoOCl7YrXB5eEl3xUL/auWRZuCI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32505 uniprotkb:P32505 intact:EBI-11770|ensemblfungi:YGL122C|uniprotkb:D6VU26 intact:EBI-11770|ensemblfungi:YGL122C|uniprotkb:D6VU26 psi-mi:nab2_yeast(display_long)|uniprotkb:YGL122C(locus name)|uniprotkb:NAB2(gene name)|psi-mi:NAB2(display_short) psi-mi:nab2_yeast(display_long)|uniprotkb:YGL122C(locus name)|uniprotkb:NAB2(gene name)|psi-mi:NAB2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322644|imex:IM-14275-795 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL122C(gene)|ensemblfungi:YGL122C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008312"(7S RNA binding)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0046872"(metal ion binding)|go:"GO:1900152"(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR021083|interpro:IPR040366|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|interpro:IPR041044|interpro:IPR043094|rcsb pdb:2JPS|rcsb pdb:2LHN|rcsb pdb:2V75|rcsb pdb:3LCN|rcsb pdb:3ZJ1|rcsb pdb:3ZJ2|rcsb pdb:4JLQ|rcsb pdb:5L2L|refseq:NP_011393.3|sgd:S000003090|mint:P32505|dip:DIP-1331N ensemblfungi:YGL122C(gene)|ensemblfungi:YGL122C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008312"(7S RNA binding)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0046872"(metal ion binding)|go:"GO:1900152"(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR021083|interpro:IPR040366|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|interpro:IPR041044|interpro:IPR043094|rcsb pdb:2JPS|rcsb pdb:2LHN|rcsb pdb:2V75|rcsb pdb:3LCN|rcsb pdb:3ZJ1|rcsb pdb:3ZJ2|rcsb pdb:4JLQ|rcsb pdb:5L2L|refseq:NP_011393.3|sgd:S000003090|mint:P32505|dip:DIP-1331N psi-mi:"MI:0469"(intact) crc64:40335C3D4658DD91 crc64:40335C3D4658DD91 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tNdhCVVTRYjqg7BES5wD2Gg4rjw559292 rogid:tNdhCVVTRYjqg7BES5wD2Gg4rjw559292 intact-crc:8140C4FF72586ABB|rigid:BHggDBy249Kr4dk+nBlNujLa5eU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32502 uniprotkb:Q12043 intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C intact:EBI-34845|uniprotkb:Q7LH13|uniprotkb:D6W2E4|ensemblfungi:YOR081C psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name) psi-mi:tgl5_yeast(display_long)|uniprotkb:TGL5(gene name)|psi-mi:TGL5(display_short)|uniprotkb:STC2(gene name synonym)|uniprotkb:YOR29-32(orf name)|uniprotkb:YOR2964C(orf name)|uniprotkb:YOR081C(locus name)|uniprotkb:Lipase 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322633|imex:IM-14275-794 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_014724.1|sgd:S000005607|mint:Q12043|dip:DIP-6280N|ensemblfungi:YOR081C(gene)|ensemblfungi:YOR081C_mRNA(transcript)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042171"(lysophosphatidic acid acyltransferase activity)|interpro:IPR002641(Patatin)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR021771 psi-mi:"MI:0469"(intact) crc64:A5409FAF1594854C - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292 rogid:ccHxygbWfyyQXKaSbOL4iYhikms559292 intact-crc:B0F2AA58CD09AA94|rigid:cnzC2pZ9lN2u2Pvh0MnmjTfkTn0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32558 uniprotkb:P20434 intact:EBI-4334|ensemblfungi:YGL207W|uniprotkb:D6VTU8 intact:EBI-15781|uniprotkb:Q02121|ensemblfungi:YBR154C|uniprotkb:D6VQE9 psi-mi:spt16_yeast(display_long)|uniprotkb:SPT16(gene name)|psi-mi:SPT16(display_short)|uniprotkb:CDC68(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:YGL207W(locus name)|uniprotkb:Facilitates chromatin transcription complex subunit SPT16(gene name synonym)|uniprotkb:Suppressor of Ty protein 16(gene name synonym)|uniprotkb:Cell division control protein 68(gene name synonym) psi-mi:rpab1_yeast(display_long)|uniprotkb:RPB5(gene name)|psi-mi:RPB5(display_short)|uniprotkb:YBR154C(locus name)|uniprotkb:YBR1204(orf name)|uniprotkb:RPA7(gene name synonym)|uniprotkb:RPC9(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide(gene name synonym)|uniprotkb:ABC27(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322655|imex:IM-14275-796 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-2546N|ensemblfungi:YGL207W(gene)|ensemblfungi:YGL207W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007063"(regulation of sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011308.1|sgd:S000003175|mint:P32558|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR013953(FACT complex subunit Spt16p/Cdc68p)|interpro:IPR029148|interpro:IPR029149|interpro:IPR033825|interpro:IPR036005|interpro:IPR040258|rcsb pdb:3BIP|rcsb pdb:3BIQ|rcsb pdb:3BIT|rcsb pdb:4IOY|rcsb pdb:4WNN|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6804756|reactome:R-SCE-75955 rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|rcsb pdb:1WCM|rcsb pdb:1Y1V|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|rcsb pdb:2B63|rcsb pdb:2B8K|interpro:IPR020608|interpro:IPR020609|rcsb pdb:2E2H|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:1DZF|rcsb pdb:1I3Q|rcsb pdb:2E2I|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:5M5Y|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6H67|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:2E2J|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|ensemblfungi:YBR154C(gene)|ensemblfungi:YBR154C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4V1M|rcsb pdb:2JA5|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2JA6|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:2JA7|rcsb pdb:3GTG|rcsb pdb:2JA8|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:2NVQ|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4YM7|rcsb pdb:5C3E|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5G5L|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6H68|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|rcsb pdb:6UQ2|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-77075|reactome:R-SCE-9018519|refseq:NP_009712.1|sgd:S000000358|dip:DIP-71N|mint:P20434 psi-mi:"MI:0469"(intact) crc64:4F01C772E299E2E6 crc64:2A15F7114D69D829 figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BjmFZfhrj4mp5mz0vNNG1JS4Hrk559292 rogid:j/jAJ2fXWf4ebK1aWTWrKERGUpM559292 intact-crc:C23A38569F0A085F|rigid:5M469WqoRA98KpvpgPkHhLZSmjs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32558 uniprotkb:P21304 intact:EBI-4334|ensemblfungi:YGL207W|uniprotkb:D6VTU8 intact:EBI-14328|uniprotkb:D6VYJ9|ensemblfungi:YLR196W psi-mi:spt16_yeast(display_long)|uniprotkb:SPT16(gene name)|psi-mi:SPT16(display_short)|uniprotkb:CDC68(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:YGL207W(locus name)|uniprotkb:Facilitates chromatin transcription complex subunit SPT16(gene name synonym)|uniprotkb:Suppressor of Ty protein 16(gene name synonym)|uniprotkb:Cell division control protein 68(gene name synonym) psi-mi:pwp1_yeast(display_long)|uniprotkb:L8167.10(orf name)|uniprotkb:YLR196W(locus name)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322666|imex:IM-14275-797 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-2546N|ensemblfungi:YGL207W(gene)|ensemblfungi:YGL207W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007063"(regulation of sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011308.1|sgd:S000003175|mint:P32558|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR013953(FACT complex subunit Spt16p/Cdc68p)|interpro:IPR029148|interpro:IPR029149|interpro:IPR033825|interpro:IPR036005|interpro:IPR040258|rcsb pdb:3BIP|rcsb pdb:3BIQ|rcsb pdb:3BIT|rcsb pdb:4IOY|rcsb pdb:4WNN|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6804756|reactome:R-SCE-75955 refseq:NP_013297.1|sgd:S000004186|ensemblfungi:YLR196W(gene)|ensemblfungi:YLR196W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR044285|mint:P21304|dip:DIP-4203N psi-mi:"MI:0469"(intact) crc64:4F01C772E299E2E6 crc64:FC0189B289494AB5 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BjmFZfhrj4mp5mz0vNNG1JS4Hrk559292 rogid:Q1nPXtlkpIw8JosaiYX0PSVNaSw559292 intact-crc:86E517479362B426|rigid:8LGNxPoZljo8gUPzu7Pd+J412KQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32558 uniprotkb:P38312 intact:EBI-4334|ensemblfungi:YGL207W|uniprotkb:D6VTU8 intact:EBI-2070767|uniprotkb:D6VQK6|ensemblfungi:YBR210W psi-mi:spt16_yeast(display_long)|uniprotkb:SPT16(gene name)|psi-mi:SPT16(display_short)|uniprotkb:CDC68(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:YGL207W(locus name)|uniprotkb:Facilitates chromatin transcription complex subunit SPT16(gene name synonym)|uniprotkb:Suppressor of Ty protein 16(gene name synonym)|uniprotkb:Cell division control protein 68(gene name synonym) psi-mi:erv15_yeast(display_long)|uniprotkb:ERV15(gene name)|psi-mi:ERV15(display_short)|uniprotkb:YBR1457(orf name)|uniprotkb:YBR210W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322677|imex:IM-14275-798 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-2546N|ensemblfungi:YGL207W(gene)|ensemblfungi:YGL207W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007063"(regulation of sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011308.1|sgd:S000003175|mint:P32558|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR013953(FACT complex subunit Spt16p/Cdc68p)|interpro:IPR029148|interpro:IPR029149|interpro:IPR033825|interpro:IPR036005|interpro:IPR040258|rcsb pdb:3BIP|rcsb pdb:3BIQ|rcsb pdb:3BIT|rcsb pdb:4IOY|rcsb pdb:4WNN|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6804756|reactome:R-SCE-75955 refseq:NP_009769.1|sgd:S000000414|interpro:IPR003377(Cornichon)|interpro:IPR033466|mint:P38312|ensemblfungi:YBR210W(gene)|ensemblfungi:YBR210W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle) psi-mi:"MI:0469"(intact) crc64:4F01C772E299E2E6 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BjmFZfhrj4mp5mz0vNNG1JS4Hrk559292 rogid:fQRUDCG9X8r22TGpqyxnU+IuNSY559292 intact-crc:F0B6A5E1983000B5|rigid:ilxtI5rEXweZVC+oGvtSk+lB2XI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53751 uniprotkb:P32558 intact:EBI-28557|uniprotkb:D6W1P0|ensemblfungi:YNR065C intact:EBI-4334|ensemblfungi:YGL207W|uniprotkb:D6VTU8 psi-mi:yn94_yeast(display_long)|uniprotkb:N3539(orf name)|uniprotkb:YNR065C(locus name) psi-mi:spt16_yeast(display_long)|uniprotkb:SPT16(gene name)|psi-mi:SPT16(display_short)|uniprotkb:CDC68(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:YGL207W(locus name)|uniprotkb:Facilitates chromatin transcription complex subunit SPT16(gene name synonym)|uniprotkb:Suppressor of Ty protein 16(gene name synonym)|uniprotkb:Cell division control protein 68(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322688|imex:IM-14275-799 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014463.1|sgd:S000005348|dip:DIP-4251N|mint:P53751|ensemblfungi:YNR065C(gene)|ensemblfungi:YNR065C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778 dip:DIP-2546N|ensemblfungi:YGL207W(gene)|ensemblfungi:YGL207W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007063"(regulation of sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011308.1|sgd:S000003175|mint:P32558|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR013953(FACT complex subunit Spt16p/Cdc68p)|interpro:IPR029148|interpro:IPR029149|interpro:IPR033825|interpro:IPR036005|interpro:IPR040258|rcsb pdb:3BIP|rcsb pdb:3BIQ|rcsb pdb:3BIT|rcsb pdb:4IOY|rcsb pdb:4WNN|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6804756|reactome:R-SCE-75955 psi-mi:"MI:0469"(intact) crc64:C0361878FE4DAB90 crc64:4F01C772E299E2E6 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:7iodiUQu3ZxDDC4KQlI3CoYD1IE559292 rogid:BjmFZfhrj4mp5mz0vNNG1JS4Hrk559292 intact-crc:81115BD980F1C575|rigid:yA3rBQK9cQJYbDoxXL/+eNRUUF0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32558 uniprotkb:Q05515 intact:EBI-4334|ensemblfungi:YGL207W|uniprotkb:D6VTU8 intact:EBI-38400|uniprotkb:D6VSX6|ensemblfungi:YDR346C psi-mi:spt16_yeast(display_long)|uniprotkb:SPT16(gene name)|psi-mi:SPT16(display_short)|uniprotkb:CDC68(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:YGL207W(locus name)|uniprotkb:Facilitates chromatin transcription complex subunit SPT16(gene name synonym)|uniprotkb:Suppressor of Ty protein 16(gene name synonym)|uniprotkb:Cell division control protein 68(gene name synonym) psi-mi:svf1_yeast(display_long)|uniprotkb:SVF1(gene name)|psi-mi:SVF1(display_short)|uniprotkb:SGI1(gene name synonym)|uniprotkb:YDR346C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322699|imex:IM-14275-800 author score:99.26 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-2546N|ensemblfungi:YGL207W(gene)|ensemblfungi:YGL207W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007063"(regulation of sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011308.1|sgd:S000003175|mint:P32558|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR013953(FACT complex subunit Spt16p/Cdc68p)|interpro:IPR029148|interpro:IPR029149|interpro:IPR033825|interpro:IPR036005|interpro:IPR040258|rcsb pdb:3BIP|rcsb pdb:3BIQ|rcsb pdb:3BIT|rcsb pdb:4IOY|rcsb pdb:4WNN|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6804756|reactome:R-SCE-75955 sgd:S000002754|refseq:NP_010633.3|mint:Q05515|dip:DIP-5243N|ensemblfungi:YDR346C(gene)|ensemblfungi:YDR346C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034599"(cellular response to oxidative stress)|interpro:IPR013931(Oxidative stress survival, Svf1-like)|interpro:IPR033394 psi-mi:"MI:0469"(intact) crc64:4F01C772E299E2E6 crc64:926A28FE140F87A5 figure legend:tables S3 and S4|author-confidence:99.26|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BjmFZfhrj4mp5mz0vNNG1JS4Hrk559292 rogid:K9DLW9y+JFX3NTUKWKHVb/YpPVg559292 intact-crc:406246757FC36CDE|rigid:pygxTznJK7zxKfWorrh09Gvqx7E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32563 uniprotkb:P32366 intact:EBI-20455|uniprotkb:D6W2X0|ensemblfungi:YOR270C intact:EBI-20201|uniprotkb:D6VZ81|ensemblfungi:YLR447C psi-mi:vph1_yeast(display_long)|uniprotkb:VPH1(gene name)|psi-mi:VPH1(display_short)|uniprotkb:Vacuolar proton pump a subunit(gene name synonym)|uniprotkb:V-ATPase 95 kDa subunit(gene name synonym)|uniprotkb:Vacuolar pH protein 1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase subunit a 1(gene name synonym)|uniprotkb:YOR270C(locus name) psi-mi:va0d_yeast(display_long)|uniprotkb:VMA6(gene name)|psi-mi:VMA6(display_short)|uniprotkb:YLR447C(locus name)|uniprotkb:L9324.8(orf name)|uniprotkb:Vacuolar proton pump subunit d(gene name synonym)|uniprotkb:V-ATPase 39 kDa subunit(gene name synonym)|uniprotkb:V-ATPase subunit M39(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322710|imex:IM-14275-801 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005796|refseq:NP_014913.3|ensemblfungi:YOR270C(gene)|ensemblfungi:YOR270C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0034622"|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:0071469"(cellular response to alkaline pH)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|rcsb pdb:2JTW|rcsb pdb:2NVJ|rcsb pdb:2RPW|rcsb pdb:3J9T|go:"GO:0007035"(vacuolar acidification)|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5I1M|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6HH0|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2960N|mint:P32563 sgd:S000004439|refseq:NP_013552.3|mint:P32366|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR036079|interpro:IPR044911|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|ensemblfungi:YLR447C(gene)|ensemblfungi:YLR447C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|rcsb pdb:6PE4|dip:DIP-1737N psi-mi:"MI:0469"(intact) crc64:77709A914410CD4D crc64:53A19450CAF35632 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:c+aKW/ZUnBlGW7ZqOLD/0mpICdQ559292 rogid:Ux3Cd8Fl9t/GGgcKAzJevZQFWnE559292 intact-crc:10F3D424B8CE9088|rigid:09YDVLEiuSJ7h6po9FyS9scqtqY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32610 uniprotkb:P32563 intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W intact:EBI-20455|uniprotkb:D6W2X0|ensemblfungi:YOR270C psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym) psi-mi:vph1_yeast(display_long)|uniprotkb:VPH1(gene name)|psi-mi:VPH1(display_short)|uniprotkb:Vacuolar proton pump a subunit(gene name synonym)|uniprotkb:V-ATPase 95 kDa subunit(gene name synonym)|uniprotkb:Vacuolar pH protein 1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase subunit a 1(gene name synonym)|uniprotkb:YOR270C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322721|imex:IM-14275-802 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610 sgd:S000005796|refseq:NP_014913.3|ensemblfungi:YOR270C(gene)|ensemblfungi:YOR270C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0034622"|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:0071469"(cellular response to alkaline pH)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|rcsb pdb:2JTW|rcsb pdb:2NVJ|rcsb pdb:2RPW|rcsb pdb:3J9T|go:"GO:0007035"(vacuolar acidification)|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5I1M|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6HH0|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2960N|mint:P32563 psi-mi:"MI:0469"(intact) crc64:FDE93E1FAF0AEC5B crc64:77709A914410CD4D figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292 rogid:c+aKW/ZUnBlGW7ZqOLD/0mpICdQ559292 intact-crc:95FA39FA6FA89323|rigid:X+3GD56Ce28R071BFqxwrLDBVF8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38310 uniprotkb:P32563 intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W intact:EBI-20455|uniprotkb:D6W2X0|ensemblfungi:YOR270C psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:vph1_yeast(display_long)|uniprotkb:VPH1(gene name)|psi-mi:VPH1(display_short)|uniprotkb:Vacuolar proton pump a subunit(gene name synonym)|uniprotkb:V-ATPase 95 kDa subunit(gene name synonym)|uniprotkb:Vacuolar pH protein 1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase subunit a 1(gene name synonym)|uniprotkb:YOR270C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322732|imex:IM-14275-803 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) sgd:S000005796|refseq:NP_014913.3|ensemblfungi:YOR270C(gene)|ensemblfungi:YOR270C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0034622"|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:0071469"(cellular response to alkaline pH)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|rcsb pdb:2JTW|rcsb pdb:2NVJ|rcsb pdb:2RPW|rcsb pdb:3J9T|go:"GO:0007035"(vacuolar acidification)|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5I1M|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6HH0|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2960N|mint:P32563 psi-mi:"MI:0469"(intact) crc64:7B4E620ABC39A053 crc64:77709A914410CD4D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 rogid:c+aKW/ZUnBlGW7ZqOLD/0mpICdQ559292 intact-crc:C567B385F2595C62|rigid:duwtopUXz1bxbMGmlkja2KiZlWs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32563 uniprotkb:P38929 intact:EBI-20455|uniprotkb:D6W2X0|ensemblfungi:YOR270C intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W psi-mi:vph1_yeast(display_long)|uniprotkb:VPH1(gene name)|psi-mi:VPH1(display_short)|uniprotkb:Vacuolar proton pump a subunit(gene name synonym)|uniprotkb:V-ATPase 95 kDa subunit(gene name synonym)|uniprotkb:Vacuolar pH protein 1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase subunit a 1(gene name synonym)|uniprotkb:YOR270C(locus name) psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322743|imex:IM-14275-804 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005796|refseq:NP_014913.3|ensemblfungi:YOR270C(gene)|ensemblfungi:YOR270C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0034622"|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:0071469"(cellular response to alkaline pH)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|rcsb pdb:2JTW|rcsb pdb:2NVJ|rcsb pdb:2RPW|rcsb pdb:3J9T|go:"GO:0007035"(vacuolar acidification)|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5I1M|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6HH0|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2960N|mint:P32563 refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 psi-mi:"MI:0469"(intact) crc64:77709A914410CD4D crc64:5BD9ECFF8508F396 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:c+aKW/ZUnBlGW7ZqOLD/0mpICdQ559292 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 intact-crc:40DE6835DD1C8839|rigid:TZ00WRgYIvXYGV/whhKjtTPD5R4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32563 uniprotkb:P39111 intact:EBI-20455|uniprotkb:D6W2X0|ensemblfungi:YOR270C intact:EBI-20272|uniprotkb:D6VUF5|ensemblfungi:YGR020C psi-mi:vph1_yeast(display_long)|uniprotkb:VPH1(gene name)|psi-mi:VPH1(display_short)|uniprotkb:Vacuolar proton pump a subunit(gene name synonym)|uniprotkb:V-ATPase 95 kDa subunit(gene name synonym)|uniprotkb:Vacuolar pH protein 1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase subunit a 1(gene name synonym)|uniprotkb:YOR270C(locus name) psi-mi:vatf_yeast(display_long)|uniprotkb:VMA7(gene name)|psi-mi:VMA7(display_short)|uniprotkb:YGR020C(locus name)|uniprotkb:Vacuolar proton pump subunit F(gene name synonym)|uniprotkb:V-ATPase 14 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322754|imex:IM-14275-805 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005796|refseq:NP_014913.3|ensemblfungi:YOR270C(gene)|ensemblfungi:YOR270C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0034622"|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:0071469"(cellular response to alkaline pH)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|rcsb pdb:2JTW|rcsb pdb:2NVJ|rcsb pdb:2RPW|rcsb pdb:3J9T|go:"GO:0007035"(vacuolar acidification)|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5I1M|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6HH0|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2960N|mint:P32563 refseq:NP_011534.1|sgd:S000003252|ensemblfungi:YGR020C(gene)|ensemblfungi:YGR020C_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016020"(membrane)|go:"GO:0042625"(ATPase-coupled ion transmembrane transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005772(ATPase, V1 complex, subunit F, eukaryotic)|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|interpro:IPR036906|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4IX9|rcsb pdb:4RND|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2077N|mint:P39111 psi-mi:"MI:0469"(intact) crc64:77709A914410CD4D crc64:D21EC0980EB99DFF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:c+aKW/ZUnBlGW7ZqOLD/0mpICdQ559292 rogid:VtthQl2jj9fpjv3psX0YUNbIAKU559292 intact-crc:3BC3568E78EA6FFB|rigid:ZceeigccP5OYA2j4C+ZrtVj8sq8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32563 uniprotkb:P41807 intact:EBI-20455|uniprotkb:D6W2X0|ensemblfungi:YOR270C intact:EBI-20281|uniprotkb:D6W446|ensemblfungi:YPR036W psi-mi:vph1_yeast(display_long)|uniprotkb:VPH1(gene name)|psi-mi:VPH1(display_short)|uniprotkb:Vacuolar proton pump a subunit(gene name synonym)|uniprotkb:V-ATPase 95 kDa subunit(gene name synonym)|uniprotkb:Vacuolar pH protein 1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase subunit a 1(gene name synonym)|uniprotkb:YOR270C(locus name) psi-mi:vath_yeast(display_long)|uniprotkb:YP3085.02(orf name)|uniprotkb:VMA13(gene name)|psi-mi:VMA13(display_short)|uniprotkb:CLS11(gene name synonym)|uniprotkb:YPR036W(locus name)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 54 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322765|imex:IM-14275-806 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005796|refseq:NP_014913.3|ensemblfungi:YOR270C(gene)|ensemblfungi:YOR270C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0034622"|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:0071469"(cellular response to alkaline pH)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|rcsb pdb:2JTW|rcsb pdb:2NVJ|rcsb pdb:2RPW|rcsb pdb:3J9T|go:"GO:0007035"(vacuolar acidification)|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5I1M|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6HH0|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2960N|mint:P32563 refseq:NP_015361.1|sgd:S000006240|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|rcsb pdb:1HO8|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YPR036W(gene)|ensemblfungi:YPR036W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|dip:DIP-6640N|mint:P41807 psi-mi:"MI:0469"(intact) crc64:77709A914410CD4D crc64:54131FF9C2C87594 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:c+aKW/ZUnBlGW7ZqOLD/0mpICdQ559292 rogid:kEXWvOsnTk0WdgGOny+mufz4lTo559292 intact-crc:F6A5C16B869754D4|rigid:Itsmnft8sFW/soD6l5nvji5GU/A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32563 uniprotkb:P53262 intact:EBI-20455|uniprotkb:D6W2X0|ensemblfungi:YOR270C intact:EBI-2061527|uniprotkb:D6VUN8|ensemblfungi:YGR106C psi-mi:vph1_yeast(display_long)|uniprotkb:VPH1(gene name)|psi-mi:VPH1(display_short)|uniprotkb:Vacuolar proton pump a subunit(gene name synonym)|uniprotkb:V-ATPase 95 kDa subunit(gene name synonym)|uniprotkb:Vacuolar pH protein 1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase subunit a 1(gene name synonym)|uniprotkb:YOR270C(locus name) psi-mi:voa1_yeast(display_long)|uniprotkb:YGR106C(locus name)|uniprotkb:VOA1(gene name)|psi-mi:VOA1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322776|imex:IM-14275-807 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005796|refseq:NP_014913.3|ensemblfungi:YOR270C(gene)|ensemblfungi:YOR270C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0034622"|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:0071469"(cellular response to alkaline pH)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|rcsb pdb:2JTW|rcsb pdb:2NVJ|rcsb pdb:2RPW|rcsb pdb:3J9T|go:"GO:0007035"(vacuolar acidification)|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5I1M|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6HH0|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2960N|mint:P32563 sgd:S000003338|refseq:NP_011620.1|mint:P53262|ensemblfungi:YGR106C(gene)|ensemblfungi:YGR106C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034622"|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|rcsb pdb:6PE4|rcsb pdb:6PE5 psi-mi:"MI:0469"(intact) crc64:77709A914410CD4D - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:c+aKW/ZUnBlGW7ZqOLD/0mpICdQ559292 rogid:lKLIonttSEX36IQaIKlzxS/Cdxg559292 intact-crc:8A802FBB82BC6931|rigid:aGEjFdFDtz9tWkrn6wvTf/AC4W8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P32563 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-20455|uniprotkb:D6W2X0|ensemblfungi:YOR270C psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:vph1_yeast(display_long)|uniprotkb:VPH1(gene name)|psi-mi:VPH1(display_short)|uniprotkb:Vacuolar proton pump a subunit(gene name synonym)|uniprotkb:V-ATPase 95 kDa subunit(gene name synonym)|uniprotkb:Vacuolar pH protein 1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase subunit a 1(gene name synonym)|uniprotkb:YOR270C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322787|imex:IM-14275-808 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 sgd:S000005796|refseq:NP_014913.3|ensemblfungi:YOR270C(gene)|ensemblfungi:YOR270C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0034622"|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:0071469"(cellular response to alkaline pH)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|rcsb pdb:2JTW|rcsb pdb:2NVJ|rcsb pdb:2RPW|rcsb pdb:3J9T|go:"GO:0007035"(vacuolar acidification)|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5I1M|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6HH0|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2960N|mint:P32563 psi-mi:"MI:0469"(intact) crc64:0EA42A599E2B2E2A crc64:77709A914410CD4D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:c+aKW/ZUnBlGW7ZqOLD/0mpICdQ559292 intact-crc:598A87D9BEBB681A|rigid:HkUDPzLSjrfmzVjMAOOXgLIxBvg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:P32566 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-17452|uniprotkb:D6VV09|ensemblfungi:YGR229C psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:smi1_yeast(display_long)|uniprotkb:SMI1(gene name)|psi-mi:SMI1(display_short)|uniprotkb:KNR4(gene name synonym)|uniprotkb:KTR4(gene name synonym)|uniprotkb:G8553(orf name)|uniprotkb:YGR229C(locus name)|uniprotkb:Killer toxin-resistance protein 4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322798|imex:IM-14275-809 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 refseq:NP_011745.1|sgd:S000003461|ensemblfungi:YGR229C(gene)|ensemblfungi:YGR229C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0032995"(regulation of fungal-type cell wall biogenesis)|go:"GO:0042546"(cell wall biogenesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0071555"(cell wall organization)|interpro:IPR009203(Cell wall assembly and cell proliferation coordinating protein, KNR4 type)|interpro:IPR018958|interpro:IPR037883|rcsb pdb:5J1B|rcsb pdb:6QBM|rcsb pdb:6QBN|rcsb pdb:6QBO|rcsb pdb:6QBP|rcsb pdb:6QBQ|rcsb pdb:6QBR|dip:DIP-1635N|mint:P32566 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:fKOvuaqVdjCWrtU9EpS+ym5MmYo559292 intact-crc:664A5F1B341D60DC|rigid:1Vl6Kz1G0OkYYOhfGIIT/+LlZng false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32566 uniprotkb:P11075 intact:EBI-17452|uniprotkb:D6VV09|ensemblfungi:YGR229C intact:EBI-16882|uniprotkb:Q03960|uniprotkb:Q04139|uniprotkb:D6VSF1|ensemblfungi:YDR170C psi-mi:smi1_yeast(display_long)|uniprotkb:SMI1(gene name)|psi-mi:SMI1(display_short)|uniprotkb:KNR4(gene name synonym)|uniprotkb:KTR4(gene name synonym)|uniprotkb:G8553(orf name)|uniprotkb:YGR229C(locus name)|uniprotkb:Killer toxin-resistance protein 4(gene name synonym) psi-mi:sec7_yeast(display_long)|uniprotkb:SEC7(gene name)|psi-mi:SEC7(display_short)|uniprotkb:YD9395.01C(orf name)|uniprotkb:YD9489.05C(orf name)|uniprotkb:YDR170C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322809|imex:IM-14275-810 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011745.1|sgd:S000003461|ensemblfungi:YGR229C(gene)|ensemblfungi:YGR229C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0032995"(regulation of fungal-type cell wall biogenesis)|go:"GO:0042546"(cell wall biogenesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0071555"(cell wall organization)|interpro:IPR009203(Cell wall assembly and cell proliferation coordinating protein, KNR4 type)|interpro:IPR018958|interpro:IPR037883|rcsb pdb:5J1B|rcsb pdb:6QBM|rcsb pdb:6QBN|rcsb pdb:6QBO|rcsb pdb:6QBP|rcsb pdb:6QBQ|rcsb pdb:6QBR|dip:DIP-1635N|mint:P32566 refseq:NP_010454.3|ensemblfungi:YDR170C(gene)|ensemblfungi:YDR170C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005770"(late endosome)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0032012"(regulation of ARF protein signal transduction)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|rcsb pdb:4OIY|go:"GO:0015031"(protein transport)|sgd:S000002577|dip:DIP-830N|mint:P11075 psi-mi:"MI:0469"(intact) - crc64:02B2D370DD2E4661 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fKOvuaqVdjCWrtU9EpS+ym5MmYo559292 rogid:BoKfHXfAHnYKyYGbglgZr/3djRw559292 intact-crc:37869CEA0BD1AC95|rigid:+ti8iLqQ/Rs9M13pEPEwJzqcBzs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13134 uniprotkb:P32566 intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5 intact:EBI-17452|uniprotkb:D6VV09|ensemblfungi:YGR229C psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym) psi-mi:smi1_yeast(display_long)|uniprotkb:SMI1(gene name)|psi-mi:SMI1(display_short)|uniprotkb:KNR4(gene name synonym)|uniprotkb:KTR4(gene name synonym)|uniprotkb:G8553(orf name)|uniprotkb:YGR229C(locus name)|uniprotkb:Killer toxin-resistance protein 4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322820|imex:IM-14275-811 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134 refseq:NP_011745.1|sgd:S000003461|ensemblfungi:YGR229C(gene)|ensemblfungi:YGR229C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0032995"(regulation of fungal-type cell wall biogenesis)|go:"GO:0042546"(cell wall biogenesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0071555"(cell wall organization)|interpro:IPR009203(Cell wall assembly and cell proliferation coordinating protein, KNR4 type)|interpro:IPR018958|interpro:IPR037883|rcsb pdb:5J1B|rcsb pdb:6QBM|rcsb pdb:6QBN|rcsb pdb:6QBO|rcsb pdb:6QBP|rcsb pdb:6QBQ|rcsb pdb:6QBR|dip:DIP-1635N|mint:P32566 psi-mi:"MI:0469"(intact) crc64:5DCEEDADCF439C78 - figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292 rogid:fKOvuaqVdjCWrtU9EpS+ym5MmYo559292 intact-crc:6E175F1CAC7966B5|rigid:LNIgqmK8TrlpsMi+QtQlCSgXWEs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:P32566 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-17452|uniprotkb:D6VV09|ensemblfungi:YGR229C psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:smi1_yeast(display_long)|uniprotkb:SMI1(gene name)|psi-mi:SMI1(display_short)|uniprotkb:KNR4(gene name synonym)|uniprotkb:KTR4(gene name synonym)|uniprotkb:G8553(orf name)|uniprotkb:YGR229C(locus name)|uniprotkb:Killer toxin-resistance protein 4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322831|imex:IM-14275-812 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) refseq:NP_011745.1|sgd:S000003461|ensemblfungi:YGR229C(gene)|ensemblfungi:YGR229C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0032995"(regulation of fungal-type cell wall biogenesis)|go:"GO:0042546"(cell wall biogenesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0071555"(cell wall organization)|interpro:IPR009203(Cell wall assembly and cell proliferation coordinating protein, KNR4 type)|interpro:IPR018958|interpro:IPR037883|rcsb pdb:5J1B|rcsb pdb:6QBM|rcsb pdb:6QBN|rcsb pdb:6QBO|rcsb pdb:6QBP|rcsb pdb:6QBQ|rcsb pdb:6QBR|dip:DIP-1635N|mint:P32566 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:fKOvuaqVdjCWrtU9EpS+ym5MmYo559292 intact-crc:812DEFEB6F853EFF|rigid:JWLxkXsOfhctaVe++3NfoSwF/HY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32566 uniprotkb:P32660 intact:EBI-17452|uniprotkb:D6VV09|ensemblfungi:YGR229C intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W psi-mi:smi1_yeast(display_long)|uniprotkb:SMI1(gene name)|psi-mi:SMI1(display_short)|uniprotkb:KNR4(gene name synonym)|uniprotkb:KTR4(gene name synonym)|uniprotkb:G8553(orf name)|uniprotkb:YGR229C(locus name)|uniprotkb:Killer toxin-resistance protein 4(gene name synonym) psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322842|imex:IM-14275-813 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011745.1|sgd:S000003461|ensemblfungi:YGR229C(gene)|ensemblfungi:YGR229C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0032995"(regulation of fungal-type cell wall biogenesis)|go:"GO:0042546"(cell wall biogenesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0071555"(cell wall organization)|interpro:IPR009203(Cell wall assembly and cell proliferation coordinating protein, KNR4 type)|interpro:IPR018958|interpro:IPR037883|rcsb pdb:5J1B|rcsb pdb:6QBM|rcsb pdb:6QBN|rcsb pdb:6QBO|rcsb pdb:6QBP|rcsb pdb:6QBQ|rcsb pdb:6QBR|dip:DIP-1635N|mint:P32566 sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) psi-mi:"MI:0469"(intact) - crc64:3CC3FBA8ADDE8960 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fKOvuaqVdjCWrtU9EpS+ym5MmYo559292 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 intact-crc:766995BDD5CEA7F2|rigid:Cub9Jb7u2cBMke21TPsVQ5FVwUw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32566 uniprotkb:P36027 intact:EBI-17452|uniprotkb:D6VV09|ensemblfungi:YGR229C intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:smi1_yeast(display_long)|uniprotkb:SMI1(gene name)|psi-mi:SMI1(display_short)|uniprotkb:KNR4(gene name synonym)|uniprotkb:KTR4(gene name synonym)|uniprotkb:G8553(orf name)|uniprotkb:YGR229C(locus name)|uniprotkb:Killer toxin-resistance protein 4(gene name synonym) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322853|imex:IM-14275-814 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011745.1|sgd:S000003461|ensemblfungi:YGR229C(gene)|ensemblfungi:YGR229C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0032995"(regulation of fungal-type cell wall biogenesis)|go:"GO:0042546"(cell wall biogenesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0071555"(cell wall organization)|interpro:IPR009203(Cell wall assembly and cell proliferation coordinating protein, KNR4 type)|interpro:IPR018958|interpro:IPR037883|rcsb pdb:5J1B|rcsb pdb:6QBM|rcsb pdb:6QBN|rcsb pdb:6QBO|rcsb pdb:6QBP|rcsb pdb:6QBQ|rcsb pdb:6QBR|dip:DIP-1635N|mint:P32566 ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fKOvuaqVdjCWrtU9EpS+ym5MmYo559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:A022C48B6A6CA98B|rigid:6vBosdQ4u8sspzSd7qV24YLtkVk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32566 uniprotkb:P38817 intact:EBI-17452|uniprotkb:D6VV09|ensemblfungi:YGR229C intact:EBI-7569|uniprotkb:D3DL58|ensemblfungi:YHR108W psi-mi:smi1_yeast(display_long)|uniprotkb:SMI1(gene name)|psi-mi:SMI1(display_short)|uniprotkb:KNR4(gene name synonym)|uniprotkb:KTR4(gene name synonym)|uniprotkb:G8553(orf name)|uniprotkb:YGR229C(locus name)|uniprotkb:Killer toxin-resistance protein 4(gene name synonym) psi-mi:gga2_yeast(display_long)|uniprotkb:YHR108W(locus name)|uniprotkb:GGA2(gene name)|psi-mi:GGA2(display_short)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322864|imex:IM-14275-815 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011745.1|sgd:S000003461|ensemblfungi:YGR229C(gene)|ensemblfungi:YGR229C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0032995"(regulation of fungal-type cell wall biogenesis)|go:"GO:0042546"(cell wall biogenesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0071555"(cell wall organization)|interpro:IPR009203(Cell wall assembly and cell proliferation coordinating protein, KNR4 type)|interpro:IPR018958|interpro:IPR037883|rcsb pdb:5J1B|rcsb pdb:6QBM|rcsb pdb:6QBN|rcsb pdb:6QBO|rcsb pdb:6QBP|rcsb pdb:6QBQ|rcsb pdb:6QBR|dip:DIP-1635N|mint:P32566 refseq:NP_011976.1|sgd:S000001150|mint:P38817|dip:DIP-2971N|ensemblfungi:YHR108W(gene)|ensemblfungi:YHR108W_mRNA(transcript)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|rcsb pdb:3MNM psi-mi:"MI:0469"(intact) - crc64:7AC3A317AEE302E2 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fKOvuaqVdjCWrtU9EpS+ym5MmYo559292 rogid:stplLxS8A9T/NqdjQXRVJTxnRsI559292 intact-crc:65319DB207507F38|rigid:Db2WvFTl6lwNBCcYa+7reDkT0Sw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39524 uniprotkb:P32566 intact:EBI-3106|uniprotkb:D6VPJ2|ensemblfungi:YAL026C intact:EBI-17452|uniprotkb:D6VV09|ensemblfungi:YGR229C psi-mi:atc3_yeast(display_long)|uniprotkb:DRS2(gene name)|psi-mi:DRS2(display_short)|uniprotkb:FUN38(orf name)|uniprotkb:YAL026C(locus name) psi-mi:smi1_yeast(display_long)|uniprotkb:SMI1(gene name)|psi-mi:SMI1(display_short)|uniprotkb:KNR4(gene name synonym)|uniprotkb:KTR4(gene name synonym)|uniprotkb:G8553(orf name)|uniprotkb:YGR229C(locus name)|uniprotkb:Killer toxin-resistance protein 4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322875|imex:IM-14275-816 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009376.2|sgd:S000000024|dip:DIP-2216N|mint:P39524|ensemblfungi:YAL026C(gene)|ensemblfungi:YAL026C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|go:"GO:1990530"(Cdc50p-Drs2p complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:6PSX|rcsb pdb:6PSY|rcsb pdb:6ROH|rcsb pdb:6ROI|rcsb pdb:6ROJ|rcsb pdb:7OH4|rcsb pdb:7OH5|rcsb pdb:7OH6|rcsb pdb:7OH7|reactome:R-SCE-6798695|reactome:R-SCE-936837 refseq:NP_011745.1|sgd:S000003461|ensemblfungi:YGR229C(gene)|ensemblfungi:YGR229C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0032995"(regulation of fungal-type cell wall biogenesis)|go:"GO:0042546"(cell wall biogenesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0071555"(cell wall organization)|interpro:IPR009203(Cell wall assembly and cell proliferation coordinating protein, KNR4 type)|interpro:IPR018958|interpro:IPR037883|rcsb pdb:5J1B|rcsb pdb:6QBM|rcsb pdb:6QBN|rcsb pdb:6QBO|rcsb pdb:6QBP|rcsb pdb:6QBQ|rcsb pdb:6QBR|dip:DIP-1635N|mint:P32566 psi-mi:"MI:0469"(intact) crc64:5745B92901F8E1AE - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:qJ8uK7dznIqyjVwjbw/VGn5Bo+4559292 rogid:fKOvuaqVdjCWrtU9EpS+ym5MmYo559292 intact-crc:D13BC4DFC4A63A85|rigid:t6roLMIuR07OPDLHw/7VR5a0aEg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32566 uniprotkb:P39719 intact:EBI-17452|uniprotkb:D6VV09|ensemblfungi:YGR229C intact:EBI-20703|uniprotkb:Q05165|uniprotkb:D6VPG5|ensemblfungi:YAL053W psi-mi:smi1_yeast(display_long)|uniprotkb:SMI1(gene name)|psi-mi:SMI1(display_short)|uniprotkb:KNR4(gene name synonym)|uniprotkb:KTR4(gene name synonym)|uniprotkb:G8553(orf name)|uniprotkb:YGR229C(locus name)|uniprotkb:Killer toxin-resistance protein 4(gene name synonym) psi-mi:flc2_yeast(display_long)|uniprotkb:YAL053W(locus name)|uniprotkb:FLC2(gene name)|psi-mi:FLC2(display_short)|uniprotkb:FAD transporter 2(gene name synonym)|uniprotkb:TRP-like ion channel FLC2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322886|imex:IM-14275-817 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011745.1|sgd:S000003461|ensemblfungi:YGR229C(gene)|ensemblfungi:YGR229C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0032995"(regulation of fungal-type cell wall biogenesis)|go:"GO:0042546"(cell wall biogenesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0071555"(cell wall organization)|interpro:IPR009203(Cell wall assembly and cell proliferation coordinating protein, KNR4 type)|interpro:IPR018958|interpro:IPR037883|rcsb pdb:5J1B|rcsb pdb:6QBM|rcsb pdb:6QBN|rcsb pdb:6QBO|rcsb pdb:6QBP|rcsb pdb:6QBQ|rcsb pdb:6QBR|dip:DIP-1635N|mint:P32566 refseq:NP_009348.2|sgd:S000000049|ensemblfungi:YAL053W(gene)|ensemblfungi:YAL053W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241|go:"GO:0055085"(transmembrane transport)|dip:DIP-6708N|mint:P39719 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fKOvuaqVdjCWrtU9EpS+ym5MmYo559292 rogid:NOmMW54DNa0o7vM945DlZgVUy44559292 intact-crc:60ECCE3F2503B82F|rigid:LkftwBk093JNUd5pA4m2V6K4SLg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32566 uniprotkb:P41810 intact:EBI-17452|uniprotkb:D6VV09|ensemblfungi:YGR229C intact:EBI-4869|uniprotkb:Q03779|uniprotkb:D6VSL9|ensemblfungi:YDR238C psi-mi:smi1_yeast(display_long)|uniprotkb:SMI1(gene name)|psi-mi:SMI1(display_short)|uniprotkb:KNR4(gene name synonym)|uniprotkb:KTR4(gene name synonym)|uniprotkb:G8553(orf name)|uniprotkb:YGR229C(locus name)|uniprotkb:Killer toxin-resistance protein 4(gene name synonym) psi-mi:copb_yeast(display_long)|uniprotkb:SEC26(gene name)|psi-mi:SEC26(display_short)|uniprotkb:YDR238C(locus name)|uniprotkb:YD8419.05C(orf name)|uniprotkb:Beta-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322897|imex:IM-14275-818 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011745.1|sgd:S000003461|ensemblfungi:YGR229C(gene)|ensemblfungi:YGR229C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0032995"(regulation of fungal-type cell wall biogenesis)|go:"GO:0042546"(cell wall biogenesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0071555"(cell wall organization)|interpro:IPR009203(Cell wall assembly and cell proliferation coordinating protein, KNR4 type)|interpro:IPR018958|interpro:IPR037883|rcsb pdb:5J1B|rcsb pdb:6QBM|rcsb pdb:6QBN|rcsb pdb:6QBO|rcsb pdb:6QBP|rcsb pdb:6QBQ|rcsb pdb:6QBR|dip:DIP-1635N|mint:P32566 sgd:S000002646|refseq:NP_010524.3|dip:DIP-6467N|mint:P41810|ensemblfungi:YDR238C(gene)|ensemblfungi:YDR238C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|reactome:R-SCE-6798695|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - crc64:885420DB026BCFA3 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fKOvuaqVdjCWrtU9EpS+ym5MmYo559292 rogid:ZfLp1BUmvVuTiXn7/Zbf/3m6VtE559292 intact-crc:3CD5498411E0C26E|rigid:jIneMeIOUOGToQ93Z58tPvkO53M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41811 uniprotkb:P32566 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W intact:EBI-17452|uniprotkb:D6VV09|ensemblfungi:YGR229C psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:smi1_yeast(display_long)|uniprotkb:SMI1(gene name)|psi-mi:SMI1(display_short)|uniprotkb:KNR4(gene name synonym)|uniprotkb:KTR4(gene name synonym)|uniprotkb:G8553(orf name)|uniprotkb:YGR229C(locus name)|uniprotkb:Killer toxin-resistance protein 4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322908|imex:IM-14275-819 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_011745.1|sgd:S000003461|ensemblfungi:YGR229C(gene)|ensemblfungi:YGR229C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0032995"(regulation of fungal-type cell wall biogenesis)|go:"GO:0042546"(cell wall biogenesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0071555"(cell wall organization)|interpro:IPR009203(Cell wall assembly and cell proliferation coordinating protein, KNR4 type)|interpro:IPR018958|interpro:IPR037883|rcsb pdb:5J1B|rcsb pdb:6QBM|rcsb pdb:6QBN|rcsb pdb:6QBO|rcsb pdb:6QBP|rcsb pdb:6QBQ|rcsb pdb:6QBR|dip:DIP-1635N|mint:P32566 psi-mi:"MI:0469"(intact) crc64:6A5E50BBEB02CB58 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 rogid:fKOvuaqVdjCWrtU9EpS+ym5MmYo559292 intact-crc:A36C42A234149C3A|rigid:TEY+IPKrMjeQ5jaIjBTADzYkl/o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12057 uniprotkb:P32566 intact:EBI-29838|uniprotkb:D6W2G4|ensemblfungi:YOR104W intact:EBI-17452|uniprotkb:D6VV09|ensemblfungi:YGR229C psi-mi:pin2_yeast(display_long)|uniprotkb:PIN2(gene name)|psi-mi:PIN2(display_short)|uniprotkb:YOR3214W(orf name)|uniprotkb:YOR104W(locus name) psi-mi:smi1_yeast(display_long)|uniprotkb:SMI1(gene name)|psi-mi:SMI1(display_short)|uniprotkb:KNR4(gene name synonym)|uniprotkb:KTR4(gene name synonym)|uniprotkb:G8553(orf name)|uniprotkb:YGR229C(locus name)|uniprotkb:Killer toxin-resistance protein 4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322919|imex:IM-14275-820 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005630|refseq:NP_014747.1|dip:DIP-4459N|mint:Q12057|ensemblfungi:YOR104W(gene)|ensemblfungi:YOR104W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|interpro:IPR037504 refseq:NP_011745.1|sgd:S000003461|ensemblfungi:YGR229C(gene)|ensemblfungi:YGR229C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0032995"(regulation of fungal-type cell wall biogenesis)|go:"GO:0042546"(cell wall biogenesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0071555"(cell wall organization)|interpro:IPR009203(Cell wall assembly and cell proliferation coordinating protein, KNR4 type)|interpro:IPR018958|interpro:IPR037883|rcsb pdb:5J1B|rcsb pdb:6QBM|rcsb pdb:6QBN|rcsb pdb:6QBO|rcsb pdb:6QBP|rcsb pdb:6QBQ|rcsb pdb:6QBR|dip:DIP-1635N|mint:P32566 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Zk6iUcpP++MEXuhKZ79TMOYQYqM559292 rogid:fKOvuaqVdjCWrtU9EpS+ym5MmYo559292 intact-crc:B80F3FD9929453C0|rigid:Ah4/6Y4FdhiXuwdX5omgSZ7errU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12114 uniprotkb:P32566 intact:EBI-4640|uniprotkb:D6VYX2|ensemblfungi:YLR330W intact:EBI-17452|uniprotkb:D6VV09|ensemblfungi:YGR229C psi-mi:chs5_yeast(display_long)|uniprotkb:CHS5(gene name)|psi-mi:CHS5(display_short)|uniprotkb:CAL3(gene name synonym)|uniprotkb:YLR330W(locus name)|uniprotkb:L8543.18(orf name)|uniprotkb:Protein CAL3(gene name synonym) psi-mi:smi1_yeast(display_long)|uniprotkb:SMI1(gene name)|psi-mi:SMI1(display_short)|uniprotkb:KNR4(gene name synonym)|uniprotkb:KTR4(gene name synonym)|uniprotkb:G8553(orf name)|uniprotkb:YGR229C(locus name)|uniprotkb:Killer toxin-resistance protein 4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322939|imex:IM-14275-821 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013434.1|sgd:S000004322|dip:DIP-8073N|mint:Q12114|ensemblfungi:YLR330W(gene)|ensemblfungi:YLR330W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006039"(cell wall chitin catabolic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034044"(exomer complex)|go:"GO:0043332"(mating projection tip)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001357(BRCT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031669|interpro:IPR031673|interpro:IPR036116|interpro:IPR036420|rcsb pdb:4IN3|rcsb pdb:4WJW|rcsb pdb:4YG8 refseq:NP_011745.1|sgd:S000003461|ensemblfungi:YGR229C(gene)|ensemblfungi:YGR229C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0032995"(regulation of fungal-type cell wall biogenesis)|go:"GO:0042546"(cell wall biogenesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0071555"(cell wall organization)|interpro:IPR009203(Cell wall assembly and cell proliferation coordinating protein, KNR4 type)|interpro:IPR018958|interpro:IPR037883|rcsb pdb:5J1B|rcsb pdb:6QBM|rcsb pdb:6QBN|rcsb pdb:6QBO|rcsb pdb:6QBP|rcsb pdb:6QBQ|rcsb pdb:6QBR|dip:DIP-1635N|mint:P32566 psi-mi:"MI:0469"(intact) crc64:FA92741B862814C2 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iHvfW3fNLv3HLj4Ihya1Vyt0X7I559292 rogid:fKOvuaqVdjCWrtU9EpS+ym5MmYo559292 intact-crc:A2EB99266F3945B0|rigid:It0LC6JL95ahSdzGBsoUO4eewzk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:P32568 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322950|imex:IM-14275-822 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 intact-crc:4D738C0E9DAE09A2|rigid:jFfSiRqv2rtQgRWoXeys3nH6J74 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:P32568 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322961|imex:IM-14275-823 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 intact-crc:567CB7723EE51A78|rigid:t4UNcWKaWkPj7siZn/VdRSS/qTU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32568 uniprotkb:P32568 intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322972|imex:IM-14275-824 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 intact-crc:14522C7983DFA8D5|rigid:sBBpihC2f2aTjv7BKKVTZZt+zwY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33302 uniprotkb:P32568 intact:EBI-13038|uniprotkb:D6W2L0|ensemblfungi:YOR153W intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W psi-mi:pdr5_yeast(display_long)|uniprotkb:PDR5(gene name)|psi-mi:PDR5(display_short)|uniprotkb:LEM1(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 5(gene name synonym)|uniprotkb:Suppressor of toxicity of sporidesmin(gene name synonym)|uniprotkb:YOR153W(locus name) psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322983|imex:IM-14275-825 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005679|refseq:NP_014796.3|mint:P33302|dip:DIP-6776N|ensemblfungi:YOR153W(gene)|ensemblfungi:YOR153W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR029481|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926 refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sd6SJWf6B0rDZnLVaPHyvr4lhew559292 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 intact-crc:CD7165F7B0962502|rigid:PJ21HwvE2UZd0ulNeV5rpl5EcCo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33413 uniprotkb:P32568 intact:EBI-2060312|uniprotkb:D3DKP5|ensemblfungi:YHL016C intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W psi-mi:dur3_yeast(display_long)|uniprotkb:DUR3(gene name)|psi-mi:DUR3(display_short)|uniprotkb:YHL016C(locus name) psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6322994|imex:IM-14275-826 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031155|refseq:NP_011847.1|sgd:S000001008|interpro:IPR001734(Na+/solute symporter)|interpro:IPR038377|mint:P33413|ensemblfungi:YHL016C(gene)|ensemblfungi:YHL016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0015204"(urea transmembrane transporter activity)|go:"GO:0015489"(putrescine transmembrane transporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015840"(urea transport)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery) refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oTFsdtOngA3q5wCbhK/fpVlIsz0559292 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 intact-crc:EF2149F582B576C5|rigid:hPGSbDmyWX8gdN21CSWmjUhBbIo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38695 uniprotkb:P32568 intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323005|imex:IM-14275-827 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 psi-mi:"MI:0469"(intact) crc64:6906721BAC1A5F87 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 intact-crc:27D37D177AAB0164|rigid:K/AjR0HI0g9ovaGoenQVpAm2vcw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P32568 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323027|imex:IM-14275-829 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 intact-crc:4EFA49E0D413E484|rigid:I0rT3Rh36ZLK9h1aoSPPoza8iVE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40474 uniprotkb:P32568 intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323016|imex:IM-14275-828 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 intact-crc:4380216BFA968F32|rigid:xT6hchkUf1pj2E+KrW/6y99/3nw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32568 uniprotkb:P53283 intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323038|imex:IM-14275-830 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 intact-crc:63057AD66EFDC684|rigid:2bnGAL2x1xcs4Z36ix5ehVPjPxg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53388 uniprotkb:P32568 intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323049|imex:IM-14275-831 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 psi-mi:"MI:0469"(intact) crc64:488A382656039D0B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 intact-crc:E15761342465F32A|rigid:35dIuxsZ3UhjKJshSZ5BSdcY0lM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32568 uniprotkb:Q02785 intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323060|imex:IM-14275-832 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:2AF89DAB5C7309CB|rigid:kzDA96hIWxe+g3fH401MbbhgWQA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32568 uniprotkb:Q03640 intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323071|imex:IM-14275-833 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) - crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:64C89886F4735E96|rigid:1U2/WvhGanTUirTXqn2beKkyioE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32568 uniprotkb:Q06451 intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W intact:EBI-34275|uniprotkb:D6W4F2|ensemblfungi:YPR156C psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:tpo3_yeast(display_long)|uniprotkb:TPO3(gene name)|psi-mi:TPO3(display_short)|uniprotkb:P9584.7(orf name)|uniprotkb:YPR156C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323082|imex:IM-14275-834 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 refseq:NP_015482.1|sgd:S000006360|mint:Q06451|dip:DIP-3907N|ensemblfungi:YPR156C(gene)|ensemblfungi:YPR156C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - crc64:D260ED161F800502 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 rogid:oVpx7Bjk/mK2Q7+/j05tX3gHw7k559292 intact-crc:45CE81F8BD7901C6|rigid:gLockK9CsoMRx66PRNcegXJTuHk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07824 uniprotkb:P32568 intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323093|imex:IM-14275-835 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 intact-crc:DA7D5B043107750C|rigid:7MrbikhMeDMTnB/5lmffJ6uKiFk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13517 uniprotkb:P32599 intact:EBI-4013|uniprotkb:Q07082|uniprotkb:D6VVP8|ensemblfungi:YIL034C intact:EBI-6931|uniprotkb:D6VSB5|ensemblfungi:YDR129C psi-mi:capzb_yeast(display_long)|uniprotkb:YIL034C(locus name)|uniprotkb:CAP2(gene name)|psi-mi:CAP2(display_short) psi-mi:fimb_yeast(display_long)|uniprotkb:SAC6(gene name)|psi-mi:SAC6(display_short)|uniprotkb:YDR129C(locus name)|uniprotkb:YD9302.04C(orf name)|uniprotkb:ABP67(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323104|imex:IM-14275-836 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001296|refseq:NP_012230.3|dip:DIP-836N|ensemblfungi:YIL034C(gene)|ensemblfungi:YIL034C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030447"(filamentous growth)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|reactome:R-SCE-9013405|reactome:R-SCE-983231|mint:P13517 sgd:S000002536|mint:P32599|refseq:NP_010414.3|dip:DIP-718N|ensemblfungi:YDR129C(gene)|ensemblfungi:YDR129C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0007015"(actin filament organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043332"(mating projection tip)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0070649"(formin-nucleated actin cable assembly)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR036872|interpro:IPR039959 psi-mi:"MI:0469"(intact) crc64:6E669023D1378778 crc64:9AF17D056173A690 figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Kk8QoRXeJ3IU4tLcyHI5y7hDipk559292 rogid:lkVMryjgP/LB7UgNUsosUgSla5w559292 intact-crc:B7EB288A7EB2CEC5|rigid:f6AMOciKX4t/Ldmbe+A+gHxbkkE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17555 uniprotkb:P32599 intact:EBI-4024|uniprotkb:D6W144|ensemblfungi:YNL138W intact:EBI-6931|uniprotkb:D6VSB5|ensemblfungi:YDR129C psi-mi:cap_yeast(display_long)|uniprotkb:SRV2(gene name)|psi-mi:SRV2(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:YNL138W(locus name)|uniprotkb:N1210(orf name)|uniprotkb:N1838(orf name) psi-mi:fimb_yeast(display_long)|uniprotkb:SAC6(gene name)|psi-mi:SAC6(display_short)|uniprotkb:YDR129C(locus name)|uniprotkb:YD9302.04C(orf name)|uniprotkb:ABP67(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323115|imex:IM-14275-837 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014261.1|sgd:S000005082|dip:DIP-77N|ensemblfungi:YNL138W(gene)|ensemblfungi:YNL138W_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007265"(Ras protein signal transduction)|mint:P17555|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0051014"(actin filament severing)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|rcsb pdb:1K4Z|rcsb pdb:1KQ5|reactome:R-SCE-6798695 sgd:S000002536|mint:P32599|refseq:NP_010414.3|dip:DIP-718N|ensemblfungi:YDR129C(gene)|ensemblfungi:YDR129C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0007015"(actin filament organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043332"(mating projection tip)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0070649"(formin-nucleated actin cable assembly)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR036872|interpro:IPR039959 psi-mi:"MI:0469"(intact) crc64:0EB4D41205E2D464 crc64:9AF17D056173A690 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3Fs9g+L5RnbkqYThVpOvSFrZoJ8559292 rogid:lkVMryjgP/LB7UgNUsosUgSla5w559292 intact-crc:3F94950717040AD5|rigid:dax1/aLyneJbuW3t6w+Qq5HpH+Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32599 uniprotkb:P38328 intact:EBI-6931|uniprotkb:D6VSB5|ensemblfungi:YDR129C intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C psi-mi:fimb_yeast(display_long)|uniprotkb:SAC6(gene name)|psi-mi:SAC6(display_short)|uniprotkb:YDR129C(locus name)|uniprotkb:YD9302.04C(orf name)|uniprotkb:ABP67(gene name synonym) psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323126|imex:IM-14275-838 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002536|mint:P32599|refseq:NP_010414.3|dip:DIP-718N|ensemblfungi:YDR129C(gene)|ensemblfungi:YDR129C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0007015"(actin filament organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043332"(mating projection tip)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0070649"(formin-nucleated actin cable assembly)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR036872|interpro:IPR039959 sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:9AF17D056173A690 crc64:D75C6BB8EC35EEDF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lkVMryjgP/LB7UgNUsosUgSla5w559292 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 intact-crc:166021851C73E0B8|rigid:w2J7MR53DW9ODjw2BnRqMWrLz5E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32599 uniprotkb:P40518 intact:EBI-6931|uniprotkb:D6VSB5|ensemblfungi:YDR129C intact:EBI-2750|uniprotkb:D6VVM2|ensemblfungi:YIL062C psi-mi:fimb_yeast(display_long)|uniprotkb:SAC6(gene name)|psi-mi:SAC6(display_short)|uniprotkb:YDR129C(locus name)|uniprotkb:YD9302.04C(orf name)|uniprotkb:ABP67(gene name synonym) psi-mi:arpc5_yeast(display_long)|uniprotkb:ARC15(gene name)|psi-mi:ARC15(display_short)|uniprotkb:Arp2/3 complex 16 kDa subunit(gene name synonym)|uniprotkb:YIL062C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323137|imex:IM-14275-839 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002536|mint:P32599|refseq:NP_010414.3|dip:DIP-718N|ensemblfungi:YDR129C(gene)|ensemblfungi:YDR129C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0007015"(actin filament organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043332"(mating projection tip)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0070649"(formin-nucleated actin cable assembly)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR036872|interpro:IPR039959 refseq:NP_012202.1|sgd:S000001324|dip:DIP-2101N|mint:P40518|ensemblfungi:YIL062C(gene)|ensemblfungi:YIL062C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR036743|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-6798695|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:9AF17D056173A690 crc64:10E4DAF0F0801B02 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lkVMryjgP/LB7UgNUsosUgSla5w559292 rogid:iQ0mLisINMjXPulrRyDmrLcdpzU559292 intact-crc:4E139D451ABF20BE|rigid:ZuHvk+riiYGJZxPik2YHyUf/0oM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32622 uniprotkb:P23202 intact:EBI-22350|uniprotkb:D3DLK8|ensemblfungi:YEL041W intact:EBI-20138|uniprotkb:D6W0W3|ensemblfungi:YNL229C psi-mi:yef1_yeast(display_long)|uniprotkb:YEF1(gene name)|psi-mi:YEF1(display_short)|uniprotkb:SYGP-ORF17(orf name)|uniprotkb:YEL041W(locus name) psi-mi:ure2_yeast(display_long)|uniprotkb:URE2(gene name)|psi-mi:URE2(display_short)|uniprotkb:Disulfide reductase(gene name synonym)|uniprotkb:Glutathione peroxidase(gene name synonym)|uniprotkb:N1165(orf name)|uniprotkb:YNL229C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323148|imex:IM-14275-840 author score:97.40 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010873.1|sgd:S000000767|dip:DIP-1885N|mint:P32622|ensemblfungi:YEL041W(gene)|ensemblfungi:YEL041W_mRNA(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0042736"(NADH kinase activity)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta) refseq:NP_014170.1|sgd:S000005173|ensemblfungi:YNL229C(gene)|ensemblfungi:YNL229C_mRNA(transcript)|mint:P23202|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0010044"(response to aluminum ion)|go:"GO:0032447"(protein urmylation)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR017298(Prion URE2)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:1G6W|rcsb pdb:1G6Y|rcsb pdb:1HQO|rcsb pdb:1JZR|rcsb pdb:1K0A|rcsb pdb:1K0B|rcsb pdb:1K0C|rcsb pdb:1K0D|go:"GO:0003714"(transcription corepressor activity)|dip:DIP-1308N psi-mi:"MI:0469"(intact) crc64:E8301D466249DA27 crc64:2C628976034B0F1C figure legend:tables S3 and S4|author-confidence:97.40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HAL9emGKdVRCmdDG9CMzn68CGUI559292 rogid:jjsWygBsEp8axNurMa3pxPMQJ2k559292 intact-crc:D02DADB99F8ABC20|rigid:I2Qm5xkgJgnzrNi5595x9yi+ZYE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32660 uniprotkb:P11075 intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W intact:EBI-16882|uniprotkb:Q03960|uniprotkb:Q04139|uniprotkb:D6VSF1|ensemblfungi:YDR170C psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:sec7_yeast(display_long)|uniprotkb:SEC7(gene name)|psi-mi:SEC7(display_short)|uniprotkb:YD9395.01C(orf name)|uniprotkb:YD9489.05C(orf name)|uniprotkb:YDR170C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323159|imex:IM-14275-841 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) refseq:NP_010454.3|ensemblfungi:YDR170C(gene)|ensemblfungi:YDR170C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005770"(late endosome)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0032012"(regulation of ARF protein signal transduction)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|rcsb pdb:4OIY|go:"GO:0015031"(protein transport)|sgd:S000002577|dip:DIP-830N|mint:P11075 psi-mi:"MI:0469"(intact) crc64:3CC3FBA8ADDE8960 crc64:02B2D370DD2E4661 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 rogid:BoKfHXfAHnYKyYGbglgZr/3djRw559292 intact-crc:97E346F5CA820773|rigid:9qg44MtYjiEGRhPL2lVRQrNh1kE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29465 uniprotkb:P32660 intact:EBI-4632|uniprotkb:D6VQ25|ensemblfungi:YBR023C intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W psi-mi:chs3_yeast(display_long)|uniprotkb:CHS3(gene name)|psi-mi:CHS3(display_short)|uniprotkb:CAL1(gene name synonym)|uniprotkb:DIT101(gene name synonym)|uniprotkb:KIT2(gene name synonym)|uniprotkb:YBR023C(locus name)|uniprotkb:CSD2(gene name synonym)|uniprotkb:YBR0305(orf name)|uniprotkb:Chitin-UDP acetyl-glucosaminyl transferase 3(gene name synonym)|uniprotkb:Class-IV chitin synthase 3(gene name synonym) psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323170|imex:IM-14275-842 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009579.1|sgd:S000000227|dip:DIP-2482N|mint:P29465|ensemblfungi:YBR023C(gene)|ensemblfungi:YBR023C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0004100"(chitin synthase activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030428"(cell septum)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0045009"(chitosome)|go:"GO:0071944"(cell periphery)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR004835(Fungal chitin synthase)|interpro:IPR029044|rcsb pdb:4WJW sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) psi-mi:"MI:0469"(intact) - crc64:3CC3FBA8ADDE8960 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8Ik0u35UXSJVtqfgNdo49J+nzFk559292 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 intact-crc:AC0EBACC6D2DAEEB|rigid:vaJBJPZ+rBb7MPU7+hNEvkHCqRY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32660 uniprotkb:P32660 intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323181|imex:IM-14275-843 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) psi-mi:"MI:0469"(intact) crc64:3CC3FBA8ADDE8960 crc64:3CC3FBA8ADDE8960 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 intact-crc:935836A65AD631F4|rigid:fZ/KnLPKO/KfwbZaF2tBUbEUOV0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32660 uniprotkb:P42838 intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W intact:EBI-28396|uniprotkb:D6W0M3|ensemblfungi:YNL323W psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:lem3_yeast(display_long)|uniprotkb:LEM3(gene name)|psi-mi:LEM3(display_short)|uniprotkb:BRE3(gene name synonym)|uniprotkb:Ro-sensitive 3(gene name synonym)|uniprotkb:Brefeldin-A sensitivity protein 3(gene name synonym)|uniprotkb:ROS3(gene name synonym)|uniprotkb:N0333(orf name)|uniprotkb:YNL323W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323192|imex:IM-14275-844 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) refseq:NP_014076.1|sgd:S000005267|dip:DIP-4598N|mint:P42838|ensemblfungi:YNL323W(gene)|ensemblfungi:YNL323W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044088"(regulation of vacuole organization)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0140331"(aminophospholipid translocation)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|rcsb pdb:7KY5|rcsb pdb:7KY7|rcsb pdb:7KY8|rcsb pdb:7KY9|rcsb pdb:7KYA|rcsb pdb:7KYB|rcsb pdb:7KYC|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) crc64:3CC3FBA8ADDE8960 crc64:55BDA1F32251B4E6 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 rogid:YNU4U5F2bWdXZvJYQ9HK0iWX230559292 intact-crc:C6523258360C241D|rigid:K113XbAj8d/ppcLMEzF12rkjy14 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32660 uniprotkb:Q12114 intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W intact:EBI-4640|uniprotkb:D6VYX2|ensemblfungi:YLR330W psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:chs5_yeast(display_long)|uniprotkb:CHS5(gene name)|psi-mi:CHS5(display_short)|uniprotkb:CAL3(gene name synonym)|uniprotkb:YLR330W(locus name)|uniprotkb:L8543.18(orf name)|uniprotkb:Protein CAL3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323203|imex:IM-14275-845 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) refseq:NP_013434.1|sgd:S000004322|dip:DIP-8073N|mint:Q12114|ensemblfungi:YLR330W(gene)|ensemblfungi:YLR330W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006039"(cell wall chitin catabolic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034044"(exomer complex)|go:"GO:0043332"(mating projection tip)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001357(BRCT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031669|interpro:IPR031673|interpro:IPR036116|interpro:IPR036420|rcsb pdb:4IN3|rcsb pdb:4WJW|rcsb pdb:4YG8 psi-mi:"MI:0469"(intact) crc64:3CC3FBA8ADDE8960 crc64:FA92741B862814C2 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 rogid:iHvfW3fNLv3HLj4Ihya1Vyt0X7I559292 intact-crc:47DA3A3DE021D3B6|rigid:ytC46fBARrO6TrdDBp4FEQ5fJps false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32771 uniprotkb:Q08023 intact:EBI-6770|uniprotkb:D6VRI3|ensemblfungi:YDL168W intact:EBI-38592|uniprotkb:D6VY77|uniprotkb:Q66R51|uniprotkb:Q7LI62|ensemblfungi:YLR077W psi-mi:fadh_yeast(display_long)|uniprotkb:YDL168W(locus name)|uniprotkb:SFA1(gene name)|psi-mi:SFA1(display_short)|uniprotkb:SFA(gene name synonym)|uniprotkb:Glutathione-dependent formaldehyde dehydrogenase(gene name synonym)|uniprotkb:Alcohol dehydrogenase SFA(gene name synonym) psi-mi:fmp25_yeast(display_long)|uniprotkb:Found in mitochondrial proteome protein 25(gene name synonym)|uniprotkb:FMP25(gene name)|psi-mi:FMP25(display_short)|uniprotkb:YLR077W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323214|imex:IM-14275-846 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010113.1|sgd:S000002327|dip:DIP-5366N|mint:P32771|ensemblfungi:YDL168W(gene)|ensemblfungi:YDL168W_mRNA(transcript)|go:"GO:0000947"(amino acid catabolic process to alcohol via Ehrlich pathway)|go:"GO:0004022"("alcohol dehydrogenase (NAD+) activity")|go:"GO:0004024"(alcohol dehydrogenase activity, zinc-dependent)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006069"(ethanol oxidation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0033833"("hydroxymethylfurfural reductase (NADH) activity")|go:"GO:0033859"(furaldehyde metabolic process)|go:"GO:0046294"(formaldehyde catabolic process)|go:"GO:0051903"("S-(hydroxymethyl)glutathione dehydrogenase activity")|go:"GO:0106321"("S-(hydroxymethyl)glutathione dehydrogenase NADP activity")|go:"GO:0106322"("S-(hydroxymethyl)glutathione dehydrogenase NAD activity")|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR014183("Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase")|interpro:IPR036291|reactome:R-SCE-2161541|reactome:R-SCE-5365859|reactome:R-SCE-71384 refseq:NP_013178.1|sgd:S000004067|mint:Q08023|dip:DIP-4474N|ensemblfungi:YLR077W(gene)|ensemblfungi:YLR077W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II) psi-mi:"MI:0469"(intact) - crc64:B2EE61451F2A9948 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ir/EvBgzM5jlB/oRoLg3Gf6gfQg559292 rogid:B5w6Eh63rS1PXLWMGPtWEZ7qYMU559292 intact-crc:E6A1697C24925BEF|rigid:3WwlTnt9VL4n0bjH2dKPfbooEFY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35196 uniprotkb:P32784 intact:EBI-14943|uniprotkb:D6VQ03|ensemblfungi:YBR002C intact:EBI-2086016|uniprotkb:D6VPY8|uniprotkb:Q07062|uniprotkb:Q96TV1|ensemblfungi:YBL011W psi-mi:rer2_yeast(display_long)|uniprotkb:"Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific)"(gene name synonym)|uniprotkb:YBR0107(orf name)|uniprotkb:RER2(gene name)|psi-mi:RER2(display_short)|uniprotkb:YBR002C(locus name) psi-mi:gpt1_yeast(display_long)|uniprotkb:SCT1(gene name)|psi-mi:SCT1(display_short)|uniprotkb:GAT2(gene name synonym)|uniprotkb:Dihydroxyacetone phosphate acyltransferase 1(gene name synonym)|uniprotkb:Glycerol-3-phosphate / dihydroxyacetone phosphate acyltransferase 1(gene name synonym)|uniprotkb:YBL0315(orf name)|uniprotkb:YBL0309(orf name)|uniprotkb:YBL011W(locus name)|uniprotkb:Suppressor of choline-transport mutants 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323225|imex:IM-14275-847 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036424|refseq:NP_009556.1|sgd:S000000206|interpro:IPR001441(Di-trans-poly-cis-decaprenylcistransferase)|interpro:IPR018520|ensemblfungi:YBR002C(gene)|ensemblfungi:YBR002C_mRNA(transcript)|go:"GO:0002094"(polyprenyltransferase activity)|go:"GO:0004659"(prenyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016094"(polyprenol biosynthetic process)|go:"GO:0019408"(dolichol biosynthetic process)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0045547"(dehydrodolichyl diphosphate synthase activity)|go:"GO:1904423"(dehydrodolichyl diphosphate synthase complex)|reactome:R-SCE-446199|mint:P35196 refseq:NP_009542.1|sgd:S000000107|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|mint:P32784|ensemblfungi:YBL011W(gene)|ensemblfungi:YBL011W_mRNA(transcript)|go:"GO:0004366"(glycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0016287"(glycerone-phosphate O-acyltransferase activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0102420"("sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity") psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:gVl9E/6GKqKsUp/5VLdT5XGbjUM559292 rogid:hP001xiUKC8ioTODiwrYiPAwhVU559292 intact-crc:CE86A2B9907C95B1|rigid:bB48JzMGFno5BTtkTNC8NgAODE0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32790 uniprotkb:P22137 intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C intact:EBI-4766|uniprotkb:D6VTU9|ensemblfungi:YGL206C psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short) psi-mi:clh_yeast(display_long)|uniprotkb:CHC1(gene name)|psi-mi:CHC1(display_short)|uniprotkb:YGL206C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323236|imex:IM-14275-848 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790 refseq:NP_011309.1|sgd:S000003174|dip:DIP-2279N|mint:P22137|ensemblfungi:YGL206C(gene)|ensemblfungi:YGL206C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0071439"(clathrin complex)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-432720|reactome:R-SCE-437239|reactome:R-SCE-8856828|reactome:R-SCE-8866427|reactome:R-SCE-8964038 psi-mi:"MI:0469"(intact) crc64:7FD85AA776407624 crc64:622F3083DF2FE315 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292 rogid:SAN6H3nVFozXZyTiRLaljMcIKIA559292 intact-crc:437FADBFC9702BB8|rigid:YFjtMKJxZyht5vrghjKg0u6fAcQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32790 uniprotkb:P32790 intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short) psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323247|imex:IM-14275-849 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790 refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790 psi-mi:"MI:0469"(intact) crc64:7FD85AA776407624 crc64:7FD85AA776407624 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292 rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292 intact-crc:89AAEF77A8FB661B|rigid:TebBlxfIyQ/E0OGZbU5wLDEFiGo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38328 uniprotkb:P32790 intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323258|imex:IM-14275-850 author score:99.32 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790 psi-mi:"MI:0469"(intact) crc64:D75C6BB8EC35EEDF crc64:7FD85AA776407624 figure legend:tables S3 and S4|author-confidence:99.32|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292 intact-crc:32BD81744ACFC019|rigid:UNy92Jcjw5aebqkLo3wLkQubbLw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39013 uniprotkb:P32790 intact:EBI-6460|intact:EBI-33854|intact:EBI-30557|intact:EBI-31021|uniprotkb:D6W195|uniprotkb:Q8TFC4|uniprotkb:Q8TFD0|uniprotkb:Q8TG51|ensemblfungi:YNL084C intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C psi-mi:end3_yeast(display_long)|uniprotkb:END3(gene name)|psi-mi:END3(display_short)|uniprotkb:YNL084C(locus name)|uniprotkb:N2307(orf name)|uniprotkb:Endocytosis protein 3(gene name synonym) psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323269|imex:IM-14275-851 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014315.1|sgd:S000005028|mint:P39013|dip:DIP-2220N|ensemblfungi:YNL084C(gene)|ensemblfungi:YNL084C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0071944"(cell periphery)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR025604|reactome:R-SCE-416482|reactome:R-SCE-8856828|reactome:R-SCE-9013148|reactome:R-SCE-9013406 refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790 psi-mi:"MI:0469"(intact) - crc64:7FD85AA776407624 figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AvVFZdzX/4DkLet/+FGA8KrKfCw559292 rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292 intact-crc:4215CE16C57E8498|rigid:URo9V+UO6h1fAM3WLjyD/jHBtM8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43603 uniprotkb:P32790 intact:EBI-22980|uniprotkb:D6VTQ4|ensemblfungi:YFR024C-A intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C psi-mi:lsb3_yeast(display_long)|uniprotkb:LSB3(gene name)|psi-mi:LSB3(display_short)|uniprotkb:YFR024C(orf name)|uniprotkb:YFR024C-A(locus name) psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323280|imex:IM-14275-852 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002968|refseq:NP_219497.4|dip:DIP-6259N|mint:P43603|ensemblfungi:YFR024C-A(gene)|ensemblfungi:YFR024C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:1OOT|rcsb pdb:1SSH refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790 psi-mi:"MI:0469"(intact) crc64:F486C787B5771AAC crc64:7FD85AA776407624 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zKMZQRpG4d/at/NecQDyEi/kVKg559292 rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292 intact-crc:77A3B11FFDEFE069|rigid:M+E5QUKmeoVUi/x3O8KFDIinSmo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32793 uniprotkb:P32793 intact:EBI-24460|uniprotkb:D3DKW1|ensemblfungi:YHR016C intact:EBI-24460|uniprotkb:D3DKW1|ensemblfungi:YHR016C psi-mi:ysc84_yeast(display_long)|uniprotkb:YSC84(gene name)|psi-mi:YSC84(display_short)|uniprotkb:LSB4(gene name synonym)|uniprotkb:LAS seventeen-binding protein 4(gene name synonym)|uniprotkb:YHR016C(locus name) psi-mi:ysc84_yeast(display_long)|uniprotkb:YSC84(gene name)|psi-mi:YSC84(display_short)|uniprotkb:LSB4(gene name synonym)|uniprotkb:LAS seventeen-binding protein 4(gene name synonym)|uniprotkb:YHR016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323291|imex:IM-14275-853 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011880.1|sgd:S000001058|dip:DIP-2026N|mint:P32793|ensemblfungi:YHR016C(gene)|ensemblfungi:YHR016C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:2A08 refseq:NP_011880.1|sgd:S000001058|dip:DIP-2026N|mint:P32793|ensemblfungi:YHR016C(gene)|ensemblfungi:YHR016C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:2A08 psi-mi:"MI:0469"(intact) crc64:DE42E8ECF5B83C92 crc64:DE42E8ECF5B83C92 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hirm/OlqdPxvJNPbha68BSFIvmQ559292 rogid:hirm/OlqdPxvJNPbha68BSFIvmQ559292 intact-crc:9A61F210016D2C20|rigid:Fao2OKPhyMDjJPaNoqHHFYUdYkE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43603 uniprotkb:P32793 intact:EBI-22980|uniprotkb:D6VTQ4|ensemblfungi:YFR024C-A intact:EBI-24460|uniprotkb:D3DKW1|ensemblfungi:YHR016C psi-mi:lsb3_yeast(display_long)|uniprotkb:LSB3(gene name)|psi-mi:LSB3(display_short)|uniprotkb:YFR024C(orf name)|uniprotkb:YFR024C-A(locus name) psi-mi:ysc84_yeast(display_long)|uniprotkb:YSC84(gene name)|psi-mi:YSC84(display_short)|uniprotkb:LSB4(gene name synonym)|uniprotkb:LAS seventeen-binding protein 4(gene name synonym)|uniprotkb:YHR016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323302|imex:IM-14275-854 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002968|refseq:NP_219497.4|dip:DIP-6259N|mint:P43603|ensemblfungi:YFR024C-A(gene)|ensemblfungi:YFR024C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:1OOT|rcsb pdb:1SSH refseq:NP_011880.1|sgd:S000001058|dip:DIP-2026N|mint:P32793|ensemblfungi:YHR016C(gene)|ensemblfungi:YHR016C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:2A08 psi-mi:"MI:0469"(intact) crc64:F486C787B5771AAC crc64:DE42E8ECF5B83C92 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zKMZQRpG4d/at/NecQDyEi/kVKg559292 rogid:hirm/OlqdPxvJNPbha68BSFIvmQ559292 intact-crc:74A3B1123A6548AF|rigid:R8pjxQemMdqoLMS4NXpZfJUH2mE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32793 uniprotkb:Q08412 intact:EBI-24460|uniprotkb:D3DKW1|ensemblfungi:YHR016C intact:EBI-37580|uniprotkb:D6W2A8|ensemblfungi:YOR042W psi-mi:ysc84_yeast(display_long)|uniprotkb:YSC84(gene name)|psi-mi:YSC84(display_short)|uniprotkb:LSB4(gene name synonym)|uniprotkb:LAS seventeen-binding protein 4(gene name synonym)|uniprotkb:YHR016C(locus name) psi-mi:cue5_yeast(display_long)|uniprotkb:YOR042W(locus name)|uniprotkb:CUE5(gene name)|psi-mi:CUE5(display_short)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323313|imex:IM-14275-855 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011880.1|sgd:S000001058|dip:DIP-2026N|mint:P32793|ensemblfungi:YHR016C(gene)|ensemblfungi:YHR016C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:2A08 refseq:NP_014685.1|sgd:S000005568|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|mint:Q08412|interpro:IPR041807|ensemblfungi:YOR042W(gene)|ensemblfungi:YOR042W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043130"(ubiquitin binding)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) crc64:DE42E8ECF5B83C92 crc64:0D455F9AD637AC8D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hirm/OlqdPxvJNPbha68BSFIvmQ559292 rogid:bUu2kNMFibdM8RUj460pMdBr2UA559292 intact-crc:6DF3D7AA0307679F|rigid:3zJOTMgo7t110FbOGGiK/nVoMSs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32794 uniprotkb:P32794 intact:EBI-2310|uniprotkb:D6VZ32|ensemblfungi:YLR397C intact:EBI-2310|uniprotkb:D6VZ32|ensemblfungi:YLR397C psi-mi:afg2_yeast(display_long)|uniprotkb:AFG2(gene name)|psi-mi:AFG2(display_short)|uniprotkb:DRG1(gene name synonym)|uniprotkb:Diazaborine resistance gene 1 protein(gene name synonym)|uniprotkb:L8084.16(orf name)|uniprotkb:YLR397C(locus name) psi-mi:afg2_yeast(display_long)|uniprotkb:AFG2(gene name)|psi-mi:AFG2(display_short)|uniprotkb:DRG1(gene name synonym)|uniprotkb:Diazaborine resistance gene 1 protein(gene name synonym)|uniprotkb:L8084.16(orf name)|uniprotkb:YLR397C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323324|imex:IM-14275-856 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013501.1|sgd:S000004389|dip:DIP-4470N|mint:P32794|ensemblfungi:YLR397C(gene)|ensemblfungi:YLR397C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042493"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:7NKU refseq:NP_013501.1|sgd:S000004389|dip:DIP-4470N|mint:P32794|ensemblfungi:YLR397C(gene)|ensemblfungi:YLR397C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042493"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:7NKU psi-mi:"MI:0469"(intact) crc64:75094DFA3D401D4E crc64:75094DFA3D401D4E figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vpN6ynPPcF6JEvh4iN69jvd20uo559292 rogid:vpN6ynPPcF6JEvh4iN69jvd20uo559292 intact-crc:234EC3FDCACC7E40|rigid:YVjx7ht1hhRW0tDQ+EY+goLU7Ww false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32798 uniprotkb:P32465 intact:EBI-5006|uniprotkb:D6W314|ensemblfungi:YOR316C intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 psi-mi:cot1_yeast(display_long)|uniprotkb:COT1(gene name)|psi-mi:COT1(display_short)|uniprotkb:O6131(orf name)|uniprotkb:YOR316C(locus name) psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323335|imex:IM-14275-857 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005843|refseq:NP_014961.3|dip:DIP-7554N|mint:P32798|ensemblfungi:YOR316C(gene)|ensemblfungi:YOR316C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006824"(cobalt ion transport)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0015087"(cobalt ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410 ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HEIg6lhS698E9H3BJeESYAipNwA559292 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 intact-crc:A4BDEF68EB7F3EF9|rigid:3gDrJvFVT3kuZMA61LEncQE7mqI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32798 uniprotkb:P32798 intact:EBI-5006|uniprotkb:D6W314|ensemblfungi:YOR316C intact:EBI-5006|uniprotkb:D6W314|ensemblfungi:YOR316C psi-mi:cot1_yeast(display_long)|uniprotkb:COT1(gene name)|psi-mi:COT1(display_short)|uniprotkb:O6131(orf name)|uniprotkb:YOR316C(locus name) psi-mi:cot1_yeast(display_long)|uniprotkb:COT1(gene name)|psi-mi:COT1(display_short)|uniprotkb:O6131(orf name)|uniprotkb:YOR316C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323346|imex:IM-14275-858 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005843|refseq:NP_014961.3|dip:DIP-7554N|mint:P32798|ensemblfungi:YOR316C(gene)|ensemblfungi:YOR316C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006824"(cobalt ion transport)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0015087"(cobalt ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410 sgd:S000005843|refseq:NP_014961.3|dip:DIP-7554N|mint:P32798|ensemblfungi:YOR316C(gene)|ensemblfungi:YOR316C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006824"(cobalt ion transport)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0015087"(cobalt ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HEIg6lhS698E9H3BJeESYAipNwA559292 rogid:HEIg6lhS698E9H3BJeESYAipNwA559292 intact-crc:6C62B6636C9556AC|rigid:gRJt4bqQScQo7E1kZZckce5fNTY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32798 uniprotkb:P38310 intact:EBI-5006|uniprotkb:D6W314|ensemblfungi:YOR316C intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:cot1_yeast(display_long)|uniprotkb:COT1(gene name)|psi-mi:COT1(display_short)|uniprotkb:O6131(orf name)|uniprotkb:YOR316C(locus name) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323357|imex:IM-14275-859 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005843|refseq:NP_014961.3|dip:DIP-7554N|mint:P32798|ensemblfungi:YOR316C(gene)|ensemblfungi:YOR316C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006824"(cobalt ion transport)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0015087"(cobalt ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410 refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) - crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HEIg6lhS698E9H3BJeESYAipNwA559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:449671ADE4CFEC4C|rigid:K1zSCFzWWm7XbjHjjZtmjtnbct8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38929 uniprotkb:P32798 intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W intact:EBI-5006|uniprotkb:D6W314|ensemblfungi:YOR316C psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:cot1_yeast(display_long)|uniprotkb:COT1(gene name)|psi-mi:COT1(display_short)|uniprotkb:O6131(orf name)|uniprotkb:YOR316C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323368|imex:IM-14275-860 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 sgd:S000005843|refseq:NP_014961.3|dip:DIP-7554N|mint:P32798|ensemblfungi:YOR316C(gene)|ensemblfungi:YOR316C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006824"(cobalt ion transport)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0015087"(cobalt ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410 psi-mi:"MI:0469"(intact) crc64:5BD9ECFF8508F396 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 rogid:HEIg6lhS698E9H3BJeESYAipNwA559292 intact-crc:C12FAA1DCB8A3817|rigid:jpFqFKo7hoTLIUzWrqj1UCAsCbc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32798 uniprotkb:P39968 intact:EBI-5006|uniprotkb:D6W314|ensemblfungi:YOR316C intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W psi-mi:cot1_yeast(display_long)|uniprotkb:COT1(gene name)|psi-mi:COT1(display_short)|uniprotkb:O6131(orf name)|uniprotkb:YOR316C(locus name) psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323379|imex:IM-14275-861 author score:99.36 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005843|refseq:NP_014961.3|dip:DIP-7554N|mint:P32798|ensemblfungi:YOR316C(gene)|ensemblfungi:YOR316C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006824"(cobalt ion transport)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0015087"(cobalt ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410 sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N psi-mi:"MI:0469"(intact) - crc64:B2E75774B47E5933 figure legend:tables S3 and S4|author-confidence:99.36|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HEIg6lhS698E9H3BJeESYAipNwA559292 rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292 intact-crc:B452B698CFE2911F|rigid:zpyhySr1yO0ox4yMQs9scSSYHDg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32798 uniprotkb:P46989 intact:EBI-5006|uniprotkb:D6W314|ensemblfungi:YOR316C intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C psi-mi:cot1_yeast(display_long)|uniprotkb:COT1(gene name)|psi-mi:COT1(display_short)|uniprotkb:O6131(orf name)|uniprotkb:YOR316C(locus name) psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323390|imex:IM-14275-862 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005843|refseq:NP_014961.3|dip:DIP-7554N|mint:P32798|ensemblfungi:YOR316C(gene)|ensemblfungi:YOR316C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006824"(cobalt ion transport)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0015087"(cobalt ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410 refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HEIg6lhS698E9H3BJeESYAipNwA559292 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 intact-crc:909A41D876A2A658|rigid:PI9hOl5EvJymtuXzL2TEzhJIBTs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32798 uniprotkb:P53290 intact:EBI-5006|uniprotkb:D6W314|ensemblfungi:YOR316C intact:EBI-7962|uniprotkb:D6VUU7|ensemblfungi:YGR163W psi-mi:cot1_yeast(display_long)|uniprotkb:COT1(gene name)|psi-mi:COT1(display_short)|uniprotkb:O6131(orf name)|uniprotkb:YOR316C(locus name) psi-mi:gtr2_yeast(display_long)|uniprotkb:YGR163W(locus name)|uniprotkb:GTR2(gene name)|psi-mi:GTR2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323401|imex:IM-14275-863 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005843|refseq:NP_014961.3|dip:DIP-7554N|mint:P32798|ensemblfungi:YOR316C(gene)|ensemblfungi:YOR316C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006824"(cobalt ion transport)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0015087"(cobalt ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410 sgd:S000003395|refseq:NP_011679.3|mint:P53290|dip:DIP-4521N|ensemblfungi:YGR163W(gene)|ensemblfungi:YGR163W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000785"(chromatin)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039400|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 psi-mi:"MI:0469"(intact) - crc64:0A0D16C81F73184D figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HEIg6lhS698E9H3BJeESYAipNwA559292 rogid:+b9bPvzin/YUc5fOZZVCcFu/GEM559292 intact-crc:886D9FD71C140ADF|rigid:cDN1MPFPgdpbdwbKH1BRJAgo4Zc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32798 uniprotkb:Q02205 intact:EBI-5006|uniprotkb:D6W314|ensemblfungi:YOR316C intact:EBI-27062|uniprotkb:D6VX73|ensemblfungi:YKR007W psi-mi:cot1_yeast(display_long)|uniprotkb:COT1(gene name)|psi-mi:COT1(display_short)|uniprotkb:O6131(orf name)|uniprotkb:YOR316C(locus name) psi-mi:meh1_yeast(display_long)|uniprotkb:GSE complex subunit 2(gene name synonym)|uniprotkb:EGO complex subunit 1(gene name synonym)|uniprotkb:YKR007W(locus name)|uniprotkb:YK106(orf name)|uniprotkb:MEH1(gene name)|psi-mi:MEH1(display_short)|uniprotkb:EGO1(gene name synonym)|uniprotkb:GSE2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323412|imex:IM-14275-864 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005843|refseq:NP_014961.3|dip:DIP-7554N|mint:P32798|ensemblfungi:YOR316C(gene)|ensemblfungi:YOR316C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006824"(cobalt ion transport)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0015087"(cobalt ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410 sgd:S000001715|refseq:NP_012932.1|mint:Q02205|dip:DIP-1922N|ensemblfungi:YKR007W(gene)|ensemblfungi:YKR007W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0005829"(cytosol)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007040"(lysosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR028209|rcsb pdb:4XPM|rcsb pdb:6JWP psi-mi:"MI:0469"(intact) - crc64:995DD1E68331D050 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HEIg6lhS698E9H3BJeESYAipNwA559292 rogid:73a6e5W5wQixGg2aGXDo4A6NR2s559292 intact-crc:78E0B6AF7032C3E4|rigid:/0ouVhhiFOjEFiUOFjtnIhcm2t8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32798 uniprotkb:Q03730 intact:EBI-5006|uniprotkb:D6W314|ensemblfungi:YOR316C intact:EBI-27739|uniprotkb:Q6B2K7|uniprotkb:D6VZF6|ensemblfungi:YML018C psi-mi:cot1_yeast(display_long)|uniprotkb:COT1(gene name)|psi-mi:COT1(display_short)|uniprotkb:O6131(orf name)|uniprotkb:YOR316C(locus name) psi-mi:ymb8_yeast(display_long)|uniprotkb:YML018C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323423|imex:IM-14275-865 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005843|refseq:NP_014961.3|dip:DIP-7554N|mint:P32798|ensemblfungi:YOR316C(gene)|ensemblfungi:YOR316C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006824"(cobalt ion transport)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0015087"(cobalt ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410 sgd:S000004480|refseq:NP_013694.1|dip:DIP-4953N|mint:Q03730|ensemblfungi:YML018C(gene)|ensemblfungi:YML018C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - crc64:DEC5C3EEF293F5ED figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HEIg6lhS698E9H3BJeESYAipNwA559292 rogid:4WxEFdhqbP7pcRcTLeFHljCVQ34559292 intact-crc:77F62A0E36CC6C01|rigid:57QnNLHlpgUfojrhXGUdsEYTr/E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12016 uniprotkb:P32798 intact:EBI-29309|uniprotkb:D6W1T9|ensemblfungi:YOL129W intact:EBI-5006|uniprotkb:D6W314|ensemblfungi:YOR316C psi-mi:vps68_yeast(display_long)|uniprotkb:YOL129W(locus name)|uniprotkb:VPS68(gene name)|psi-mi:VPS68(display_short) psi-mi:cot1_yeast(display_long)|uniprotkb:COT1(gene name)|psi-mi:COT1(display_short)|uniprotkb:O6131(orf name)|uniprotkb:YOR316C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323434|imex:IM-14275-866 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014512.1|sgd:S000005489|dip:DIP-1732N|mint:Q12016|ensemblfungi:YOL129W(gene)|ensemblfungi:YOL129W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0034424"(Vps55/Vps68 complex)|interpro:IPR007919(Protein of unknown function UPF0220) sgd:S000005843|refseq:NP_014961.3|dip:DIP-7554N|mint:P32798|ensemblfungi:YOR316C(gene)|ensemblfungi:YOR316C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006824"(cobalt ion transport)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0015087"(cobalt ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410 psi-mi:"MI:0469"(intact) crc64:4B21C846AB3BA2A7 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I6sUyfNcLBsFG3OtDUfEqohxLB4559292 rogid:HEIg6lhS698E9H3BJeESYAipNwA559292 intact-crc:D63912ED71FE9589|rigid:9IYJ6EUlWpeY3ccW5f0RQ1jucb0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:P32802 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-6445|uniprotkb:Q12101|uniprotkb:D6VY83|ensemblfungi:YLR083C psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:tmn1_yeast(display_long)|uniprotkb:EMP70(gene name)|psi-mi:EMP70(display_short)|uniprotkb:YLR083C(locus name)|uniprotkb:L9449.11(orf name)|uniprotkb:70 kDa endomembrane protein(gene name synonym)|uniprotkb:L2385(orf name)|uniprotkb:TMN1(gene name synonym)|uniprotkb:Endomembrane protein EMP70(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323445|imex:IM-14275-867 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 refseq:NP_013184.1|sgd:S000004073|mint:P32802|dip:DIP-4700N|ensemblfungi:YLR083C(gene)|ensemblfungi:YLR083C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005768"(endosome)|go:"GO:0006811"(ion transport)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0072657"(protein localization to membrane)|interpro:IPR004240("Nonaspanin (TM9SF)") psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:Ow+08Z0owEDCqVRrhSIWt9ieXrE559292 intact-crc:F7F1392C099FBDCD|rigid:Ad4S0y4N3sEEb80Ei4OjoVWTFM4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:P32802 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-6445|uniprotkb:Q12101|uniprotkb:D6VY83|ensemblfungi:YLR083C psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:tmn1_yeast(display_long)|uniprotkb:EMP70(gene name)|psi-mi:EMP70(display_short)|uniprotkb:YLR083C(locus name)|uniprotkb:L9449.11(orf name)|uniprotkb:70 kDa endomembrane protein(gene name synonym)|uniprotkb:L2385(orf name)|uniprotkb:TMN1(gene name synonym)|uniprotkb:Endomembrane protein EMP70(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323456|imex:IM-14275-868 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 refseq:NP_013184.1|sgd:S000004073|mint:P32802|dip:DIP-4700N|ensemblfungi:YLR083C(gene)|ensemblfungi:YLR083C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005768"(endosome)|go:"GO:0006811"(ion transport)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0072657"(protein localization to membrane)|interpro:IPR004240("Nonaspanin (TM9SF)") psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:Ow+08Z0owEDCqVRrhSIWt9ieXrE559292 intact-crc:A53DFAD0F1D9D942|rigid:RmuHaPN88uyKozjtgBsa6+zRoDo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43621 uniprotkb:P32802 intact:EBI-4876|uniprotkb:D6VTT4|ensemblfungi:YFR051C intact:EBI-6445|uniprotkb:Q12101|uniprotkb:D6VY83|ensemblfungi:YLR083C psi-mi:copd_yeast(display_long)|uniprotkb:RET2(gene name)|psi-mi:RET2(display_short)|uniprotkb:YFR051C(locus name)|uniprotkb:Delta-coat protein(gene name synonym) psi-mi:tmn1_yeast(display_long)|uniprotkb:EMP70(gene name)|psi-mi:EMP70(display_short)|uniprotkb:YLR083C(locus name)|uniprotkb:L9449.11(orf name)|uniprotkb:70 kDa endomembrane protein(gene name synonym)|uniprotkb:L2385(orf name)|uniprotkb:TMN1(gene name synonym)|uniprotkb:Endomembrane protein EMP70(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323467|imex:IM-14275-869 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001947|refseq:NP_116709.3|dip:DIP-5255N|mint:P43621|ensemblfungi:YFR051C(gene)|ensemblfungi:YFR051C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|rcsb pdb:5FJW|rcsb pdb:5FJX|rcsb pdb:5FJZ|rcsb pdb:5FK0|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_013184.1|sgd:S000004073|mint:P32802|dip:DIP-4700N|ensemblfungi:YLR083C(gene)|ensemblfungi:YLR083C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005768"(endosome)|go:"GO:0006811"(ion transport)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0072657"(protein localization to membrane)|interpro:IPR004240("Nonaspanin (TM9SF)") psi-mi:"MI:0469"(intact) crc64:AA730F046655EE5A - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:auvjuT8ffm1R4P3mRKEIWAsynW0559292 rogid:Ow+08Z0owEDCqVRrhSIWt9ieXrE559292 intact-crc:63F0FA4CA1D3E802|rigid:c+Oha265PoNRqvY+UBYiv/XUgzM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32802 uniprotkb:Q03687 intact:EBI-6445|uniprotkb:Q12101|uniprotkb:D6VY83|ensemblfungi:YLR083C intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W psi-mi:tmn1_yeast(display_long)|uniprotkb:EMP70(gene name)|psi-mi:EMP70(display_short)|uniprotkb:YLR083C(locus name)|uniprotkb:L9449.11(orf name)|uniprotkb:70 kDa endomembrane protein(gene name synonym)|uniprotkb:L2385(orf name)|uniprotkb:TMN1(gene name synonym)|uniprotkb:Endomembrane protein EMP70(gene name synonym) psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323478|imex:IM-14275-870 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013184.1|sgd:S000004073|mint:P32802|dip:DIP-4700N|ensemblfungi:YLR083C(gene)|ensemblfungi:YLR083C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005768"(endosome)|go:"GO:0006811"(ion transport)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0072657"(protein localization to membrane)|interpro:IPR004240("Nonaspanin (TM9SF)") refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ow+08Z0owEDCqVRrhSIWt9ieXrE559292 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 intact-crc:BE0B682D2F35F225|rigid:A24jMhIn60eXbS7/cNLRKFSVuic false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08280 uniprotkb:P32802 intact:EBI-35858|uniprotkb:Q6B229|uniprotkb:D6W1T2|ensemblfungi:YOL137W intact:EBI-6445|uniprotkb:Q12101|uniprotkb:D6VY83|ensemblfungi:YLR083C psi-mi:bsc6_yeast(display_long)|uniprotkb:YOL137W(locus name)|uniprotkb:BSC6(gene name)|psi-mi:BSC6(display_short) psi-mi:tmn1_yeast(display_long)|uniprotkb:EMP70(gene name)|psi-mi:EMP70(display_short)|uniprotkb:YLR083C(locus name)|uniprotkb:L9449.11(orf name)|uniprotkb:70 kDa endomembrane protein(gene name synonym)|uniprotkb:L2385(orf name)|uniprotkb:TMN1(gene name synonym)|uniprotkb:Endomembrane protein EMP70(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323489|imex:IM-14275-871 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014504.1|sgd:S000005497|mint:Q08280|dip:DIP-4683N|ensemblfungi:YOL137W(gene)|ensemblfungi:YOL137W_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_013184.1|sgd:S000004073|mint:P32802|dip:DIP-4700N|ensemblfungi:YLR083C(gene)|ensemblfungi:YLR083C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005768"(endosome)|go:"GO:0006811"(ion transport)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0072657"(protein localization to membrane)|interpro:IPR004240("Nonaspanin (TM9SF)") psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WVYZke8YJvNcS4D9bUnthAFdq3A559292 rogid:Ow+08Z0owEDCqVRrhSIWt9ieXrE559292 intact-crc:B05A5E26F924A51B|rigid:DmiKu9g0PW/2vuPAEAtz4UCT5uM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32588 uniprotkb:P32831 intact:EBI-14231|ensemblfungi:YNL016W|uniprotkb:D6W1G2 intact:EBI-12002|ensemblfungi:YBR212W|uniprotkb:D6VQK8 psi-mi:pub1_yeast(display_long)|uniprotkb:ARS consensus-binding protein ACBP-60(gene name synonym)|uniprotkb:Poly uridylate-binding protein(gene name synonym)|uniprotkb:PUB1(gene name)|psi-mi:PUB1(display_short)|uniprotkb:RNP1(gene name synonym)|uniprotkb:YNL016W(locus name)|uniprotkb:N2842(orf name) psi-mi:ngr1_yeast(display_long)|uniprotkb:NGR1(gene name)|psi-mi:NGR1(display_short)|uniprotkb:RBP1(gene name synonym)|uniprotkb:YBR212W(locus name)|uniprotkb:YBR1459(orf name)|uniprotkb:RNA-binding protein RBP1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323500|imex:IM-14275-872 author score:99.32 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014382.1|sgd:S000004961|ensemblfungi:YNL016W(gene)|ensemblfungi:YNL016W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043488"(regulation of mRNA stability)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034509|interpro:IPR034639|interpro:IPR035979|rcsb pdb:2LA4|rcsb pdb:3MD1|rcsb pdb:3MD3|rcsb pdb:6Z29|mint:P32588|dip:DIP-5480N ensemblfungi:YBR212W(gene)|ensemblfungi:YBR212W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|refseq:NP_009771.3|sgd:S000000416|mint:P32831|dip:DIP-5160N psi-mi:"MI:0469"(intact) crc64:3B81A7735505D3CA crc64:12F64EC4C5716750 figure legend:tables S3 and S4|author-confidence:99.32|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8xFMuEva7leVYDKg3WOmvPtRTFk559292 rogid:MCNbYrmWkUp7dAyKpebSKsIzOxA559292 intact-crc:8310673469BD519B|rigid:XVs9YtcAdrrQ2bYuXgn/BXPIHPw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:D6VTK4 uniprotkb:P32844 intact:EBI-6323511|ensemblfungi:YFL026W|uniprotkb:P06842|uniprotkb:Q70D63|uniprotkb:Q70D65|uniprotkb:Q70D69|uniprotkb:Q70D73|uniprotkb:Q70D74 intact:EBI-16874|uniprotkb:D6VVL6|ensemblfungi:YIL068C psi-mi:ste2_yeast(display_long)|uniprotkb:STE2(gene name)|psi-mi:STE2(display_short)|uniprotkb:YFL026W(locus name) psi-mi:sec6_yeast(display_long)|uniprotkb:YIL068C(locus name)|uniprotkb:SEC6(gene name)|psi-mi:SEC6(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323513|imex:IM-14275-873 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YFL026W(gene)|ensemblfungi:YFL026W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000755"(cytogamy)|go:"GO:0004932"(mating-type factor pheromone receptor activity)|go:"GO:0004934"(mating-type alpha-factor pheromone receptor activity)|go:"GO:0005550"(pheromone binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0030031"(cell projection assembly)|go:"GO:0038038"(G protein-coupled receptor homodimeric complex)|rcsb pdb:1PJD|rcsb pdb:2K9P|interpro:IPR027458|mint:D6VTK4|interpro:IPR000366(Fungal pheromone mating factor STE2 GPCR)|refseq:NP_116627.2|sgd:S000001868 refseq:NP_012196.1|sgd:S000001330|ensemblfungi:YIL068C(gene)|ensemblfungi:YIL068C_mRNA(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000149"(SNARE binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0035544"(negative regulation of SNARE complex assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0051601"(exocyst localization)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR010326(Exocyst complex component Sec6)|interpro:IPR042532|rcsb pdb:2FJI|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876|dip:DIP-5649N|mint:P32844 psi-mi:"MI:0469"(intact) crc64:011F604DC2A6907E crc64:2B09BBBE15389239 figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Xw+4tatIKPl42hhE5XQUighaCP4559292 rogid:SJtUIHyBTy38oPOc0h4D3Anipvc559292 intact-crc:101B617EF99BB381|rigid:6gs9mOzPl45BYWgfZ+UXACbzLz8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32844 uniprotkb:P25357 intact:EBI-16874|uniprotkb:D6VVL6|ensemblfungi:YIL068C intact:EBI-17596|uniprotkb:Q02397|uniprotkb:Q8NIL8|uniprotkb:D6VR43|ensemblfungi:YCR033W psi-mi:sec6_yeast(display_long)|uniprotkb:YIL068C(locus name)|uniprotkb:SEC6(gene name)|psi-mi:SEC6(display_short) psi-mi:snt1_yeast(display_long)|uniprotkb:YCR33W(orf name)|uniprotkb:YCR592(orf name)|uniprotkb:SNT1(gene name)|psi-mi:SNT1(display_short)|uniprotkb:YCR033W(locus name)|uniprotkb:SANT domain-containing protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323524|imex:IM-14275-874 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012196.1|sgd:S000001330|ensemblfungi:YIL068C(gene)|ensemblfungi:YIL068C_mRNA(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000149"(SNARE binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0035544"(negative regulation of SNARE complex assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0051601"(exocyst localization)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR010326(Exocyst complex component Sec6)|interpro:IPR042532|rcsb pdb:2FJI|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876|dip:DIP-5649N|mint:P32844 go:"GO:0070210"(Rpd3L-Expanded complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|refseq:NP_009962.2|sgd:S000000629|ensemblfungi:YCR033W(gene)|ensemblfungi:YCR033W_mRNA(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0034967"(Set3 complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|dip:DIP-2082N|mint:P25357 psi-mi:"MI:0469"(intact) crc64:2B09BBBE15389239 crc64:70AE6622227088EB figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SJtUIHyBTy38oPOc0h4D3Anipvc559292 rogid:EVuZV/iAEjAR3qzOFJkHB+U6WRA559292 intact-crc:FA1B3C39AA5973C1|rigid:MM4eimCreDEIo5NTGP+LTJQ2Ld4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32844 uniprotkb:P32660 intact:EBI-16874|uniprotkb:D6VVL6|ensemblfungi:YIL068C intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W psi-mi:sec6_yeast(display_long)|uniprotkb:YIL068C(locus name)|uniprotkb:SEC6(gene name)|psi-mi:SEC6(display_short) psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323535|imex:IM-14275-875 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012196.1|sgd:S000001330|ensemblfungi:YIL068C(gene)|ensemblfungi:YIL068C_mRNA(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000149"(SNARE binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0035544"(negative regulation of SNARE complex assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0051601"(exocyst localization)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR010326(Exocyst complex component Sec6)|interpro:IPR042532|rcsb pdb:2FJI|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876|dip:DIP-5649N|mint:P32844 sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) psi-mi:"MI:0469"(intact) crc64:2B09BBBE15389239 crc64:3CC3FBA8ADDE8960 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SJtUIHyBTy38oPOc0h4D3Anipvc559292 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 intact-crc:77AFAC9EFCC4670E|rigid:HOWJrL3vZDoMpui6P31cyCFnoiQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32844 uniprotkb:P32844 intact:EBI-16874|uniprotkb:D6VVL6|ensemblfungi:YIL068C intact:EBI-16874|uniprotkb:D6VVL6|ensemblfungi:YIL068C psi-mi:sec6_yeast(display_long)|uniprotkb:YIL068C(locus name)|uniprotkb:SEC6(gene name)|psi-mi:SEC6(display_short) psi-mi:sec6_yeast(display_long)|uniprotkb:YIL068C(locus name)|uniprotkb:SEC6(gene name)|psi-mi:SEC6(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323546|imex:IM-14275-876 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012196.1|sgd:S000001330|ensemblfungi:YIL068C(gene)|ensemblfungi:YIL068C_mRNA(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000149"(SNARE binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0035544"(negative regulation of SNARE complex assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0051601"(exocyst localization)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR010326(Exocyst complex component Sec6)|interpro:IPR042532|rcsb pdb:2FJI|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876|dip:DIP-5649N|mint:P32844 refseq:NP_012196.1|sgd:S000001330|ensemblfungi:YIL068C(gene)|ensemblfungi:YIL068C_mRNA(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000149"(SNARE binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0035544"(negative regulation of SNARE complex assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0051601"(exocyst localization)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR010326(Exocyst complex component Sec6)|interpro:IPR042532|rcsb pdb:2FJI|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876|dip:DIP-5649N|mint:P32844 psi-mi:"MI:0469"(intact) crc64:2B09BBBE15389239 crc64:2B09BBBE15389239 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SJtUIHyBTy38oPOc0h4D3Anipvc559292 rogid:SJtUIHyBTy38oPOc0h4D3Anipvc559292 intact-crc:EDB41A641E0BA561|rigid:XHhHaczTIWG+toc9t1vKNMuNpcI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53604 uniprotkb:P32844 intact:EBI-2086543|uniprotkb:D6W1M4|ensemblfungi:YNR049C intact:EBI-16874|uniprotkb:D6VVL6|ensemblfungi:YIL068C psi-mi:mso1_yeast(display_long)|uniprotkb:MSO1(gene name)|psi-mi:MSO1(display_short)|uniprotkb:N3457(orf name)|uniprotkb:YNR049C(locus name) psi-mi:sec6_yeast(display_long)|uniprotkb:YIL068C(locus name)|uniprotkb:SEC6(gene name)|psi-mi:SEC6(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323557|imex:IM-14275-877 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005332|refseq:NP_014447.3|dip:DIP-2499N|mint:P53604|ensemblfungi:YNR049C(gene)|ensemblfungi:YNR049C_mRNA(transcript)|go:"GO:0005628"(prospore membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0031201"(SNARE complex)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0061025"(membrane fusion)|interpro:IPR028095 refseq:NP_012196.1|sgd:S000001330|ensemblfungi:YIL068C(gene)|ensemblfungi:YIL068C_mRNA(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000149"(SNARE binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0035544"(negative regulation of SNARE complex assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0051601"(exocyst localization)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR010326(Exocyst complex component Sec6)|interpro:IPR042532|rcsb pdb:2FJI|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876|dip:DIP-5649N|mint:P32844 psi-mi:"MI:0469"(intact) - crc64:2B09BBBE15389239 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:eOrjheH1mmf2/8BQbIorCES+FNQ559292 rogid:SJtUIHyBTy38oPOc0h4D3Anipvc559292 intact-crc:8A7910AE9DE49B72|rigid:txgOX4dsN/hKsQeUfrwrdyqIwP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P89102 uniprotkb:P32844 intact:EBI-16865|uniprotkb:Q03775|uniprotkb:Q04128|uniprotkb:D6VSE6|ensemblfungi:YDR166C intact:EBI-16874|uniprotkb:D6VVL6|ensemblfungi:YIL068C psi-mi:sec5_yeast(display_long)|uniprotkb:YD8358.20C(orf name)|uniprotkb:SEC5(gene name)|psi-mi:SEC5(display_short)|uniprotkb:YD9489.01C(orf name)|uniprotkb:YDR166C(locus name) psi-mi:sec6_yeast(display_long)|uniprotkb:YIL068C(locus name)|uniprotkb:SEC6(gene name)|psi-mi:SEC6(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323568|imex:IM-14275-878 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010450.3|ensemblfungi:YDR166C(gene)|ensemblfungi:YDR166C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000145"(exocyst)|go:"GO:0001927"(exocyst assembly)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0043332"(mating projection tip)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0071944"(cell periphery)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR029175|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876|interpro:IPR039481|sgd:S000002573|dip:DIP-2579N|mint:P89102 refseq:NP_012196.1|sgd:S000001330|ensemblfungi:YIL068C(gene)|ensemblfungi:YIL068C_mRNA(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000149"(SNARE binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0035544"(negative regulation of SNARE complex assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0051601"(exocyst localization)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR010326(Exocyst complex component Sec6)|interpro:IPR042532|rcsb pdb:2FJI|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876|dip:DIP-5649N|mint:P32844 psi-mi:"MI:0469"(intact) - crc64:2B09BBBE15389239 figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SWV3HuxYf2DehDadp3hAPEELUTU559292 rogid:SJtUIHyBTy38oPOc0h4D3Anipvc559292 intact-crc:CCF240991745A4AE|rigid:SWBpedW7Fa6RnoAg3lMJu4zOZ+w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32858 uniprotkb:Q3E776 intact:EBI-26643|uniprotkb:D6VXP9|ensemblfungi:YKL037W intact:EBI-2042805|uniprotkb:D6VQQ2|ensemblfungi:YBR255C-A psi-mi:aim26_yeast(display_long)|uniprotkb:YKL250(orf name)|uniprotkb:YKL037W(locus name)|uniprotkb:AIM26(gene name)|psi-mi:AIM26(display_short) psi-mi:yb255_yeast(display_long)|uniprotkb:YBR255C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323579|imex:IM-14275-879 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001520|refseq:NP_012887.1|mint:P32858|ensemblfungi:YKL037W(gene)|ensemblfungi:YKL037W_mRNA(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005739"(mitochondrion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0031966"(mitochondrial membrane) sgd:S000007649|interpro:IPR038882|refseq:NP_116328.4|mint:Q3E776|ensemblfungi:YBR255C-A(gene)|ensemblfungi:YBR255C-A_mRNA(transcript)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3edTHlPhltn+wwF9hQEsy3+7nAU559292 rogid:LHd4ToffLuVn2nuqg93EsoO8ouo559292 intact-crc:3DF7BD01E1CCA915|rigid:FYjxdV0x7gmcY6W0+ANMs0c5LmI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32858 uniprotkb:Q8TGU5 intact:EBI-26643|uniprotkb:D6VXP9|ensemblfungi:YKL037W intact:EBI-2042814|uniprotkb:D6VQU1|ensemblfungi:YBR296C-A psi-mi:aim26_yeast(display_long)|uniprotkb:YKL250(orf name)|uniprotkb:YKL037W(locus name)|uniprotkb:AIM26(gene name)|psi-mi:AIM26(display_short) psi-mi:yb296_yeast(display_long)|uniprotkb:YBR296C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323590|imex:IM-14275-880 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001520|refseq:NP_012887.1|mint:P32858|ensemblfungi:YKL037W(gene)|ensemblfungi:YKL037W_mRNA(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005739"(mitochondrion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0031966"(mitochondrial membrane) sgd:S000028605|refseq:NP_878055.3|mint:Q8TGU5|ensemblfungi:YBR296C-A(gene)|ensemblfungi:YBR296C-A_mRNA(transcript)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3edTHlPhltn+wwF9hQEsy3+7nAU559292 rogid:DZubWD7lnwtea4Ne/bK1ITPFaJk559292 intact-crc:30294ABB05B796B2|rigid:B2ATfkdPA59gZ7jr0zviQPHBscM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32864 uniprotkb:P32432 intact:EBI-14799|uniprotkb:Q06761|uniprotkb:D6W363|ensemblfungi:YOR370C intact:EBI-17035|uniprotkb:D6VZ36|ensemblfungi:YLR403W psi-mi:raep_yeast(display_long)|uniprotkb:YOR370C(locus name)|uniprotkb:MRS6(gene name)|psi-mi:MRS6(display_short)|uniprotkb:MSI4(gene name synonym)|uniprotkb:Rab escort protein(gene name synonym) psi-mi:sfp1_yeast(display_long)|uniprotkb:SFP1(gene name)|psi-mi:SFP1(display_short)|uniprotkb:Split finger protein 1(gene name synonym)|uniprotkb:L8084.4(orf name)|uniprotkb:YLR403W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323601|imex:IM-14275-881 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015015.1|sgd:S000005897|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005968"(Rab-protein geranylgeranyltransferase complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR017230(Rab protein geranylgeranyltransferase, component A, fungi)|interpro:IPR018203|interpro:IPR036188|reactome:R-SCE-6803205|reactome:R-SCE-8873719|reactome:R-SCE-8876198|ensemblfungi:YOR370C(gene)|ensemblfungi:YOR370C_mRNA(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|dip:DIP-2246N|mint:P32864 ensemblfungi:YLR403W(gene)|refseq:NP_013507.1|sgd:S000004395|ensemblfungi:YLR403W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008361"(regulation of cell size)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060963"(positive regulation of ribosomal protein gene transcription by RNA polymerase II)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|dip:DIP-1379N|mint:P32432 psi-mi:"MI:0469"(intact) crc64:30BB7FFF8D712FFD crc64:0332A381D75A6F14 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:quu5u+3WZxRJAobk3H2EERRUqKU559292 rogid:R5GZ+PCzhlzyWOGHfAImSHpK3hA559292 intact-crc:D82B1E51DC3D5A3C|rigid:GD8Es3c3MEP2R62GclFOu1wLag4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32864 uniprotkb:P36017 intact:EBI-14799|uniprotkb:Q06761|uniprotkb:D6W363|ensemblfungi:YOR370C intact:EBI-29399|uniprotkb:D6W2F0|ensemblfungi:YOR089C psi-mi:raep_yeast(display_long)|uniprotkb:YOR370C(locus name)|uniprotkb:MRS6(gene name)|psi-mi:MRS6(display_short)|uniprotkb:MSI4(gene name synonym)|uniprotkb:Rab escort protein(gene name synonym) psi-mi:vps21_yeast(display_long)|uniprotkb:GTP-binding protein YPT51(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 12(gene name synonym)|uniprotkb:VPS21(gene name)|psi-mi:VPS21(display_short)|uniprotkb:YOR089C(locus name)|uniprotkb:YOR3154C(orf name)|uniprotkb:VPS12(gene name synonym)|uniprotkb:VPT12(gene name synonym)|uniprotkb:YPT21(gene name synonym)|uniprotkb:YPT51(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323612|imex:IM-14275-882 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015015.1|sgd:S000005897|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005968"(Rab-protein geranylgeranyltransferase complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR017230(Rab protein geranylgeranyltransferase, component A, fungi)|interpro:IPR018203|interpro:IPR036188|reactome:R-SCE-6803205|reactome:R-SCE-8873719|reactome:R-SCE-8876198|ensemblfungi:YOR370C(gene)|ensemblfungi:YOR370C_mRNA(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|dip:DIP-2246N|mint:P32864 refseq:NP_014732.1|sgd:S000005615|dip:DIP-3801N|mint:P36017|ensemblfungi:YOR089C(gene)|ensemblfungi:YOR089C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0061709"(reticulophagy)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1EK0 psi-mi:"MI:0469"(intact) crc64:30BB7FFF8D712FFD crc64:34D7DA0090C33F09 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:quu5u+3WZxRJAobk3H2EERRUqKU559292 rogid:fo/U32XQLnHSVpuK48jddD4Kve4559292 intact-crc:13EBE29F7AC226BE|rigid:21+hrBtVxOoLlfY6gpFme+ctaBI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32864 uniprotkb:P36018 intact:EBI-14799|uniprotkb:Q06761|uniprotkb:D6W363|ensemblfungi:YOR370C intact:EBI-29407|uniprotkb:D6VX79|ensemblfungi:YKR014C psi-mi:raep_yeast(display_long)|uniprotkb:YOR370C(locus name)|uniprotkb:MRS6(gene name)|psi-mi:MRS6(display_short)|uniprotkb:MSI4(gene name synonym)|uniprotkb:Rab escort protein(gene name synonym) psi-mi:ypt52_yeast(display_long)|uniprotkb:YPT52(gene name)|psi-mi:YPT52(display_short)|uniprotkb:YK112(orf name)|uniprotkb:YKR014C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323623|imex:IM-14275-883 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015015.1|sgd:S000005897|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005968"(Rab-protein geranylgeranyltransferase complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR017230(Rab protein geranylgeranyltransferase, component A, fungi)|interpro:IPR018203|interpro:IPR036188|reactome:R-SCE-6803205|reactome:R-SCE-8873719|reactome:R-SCE-8876198|ensemblfungi:YOR370C(gene)|ensemblfungi:YOR370C_mRNA(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|dip:DIP-2246N|mint:P32864 refseq:NP_012939.1|sgd:S000001722|dip:DIP-2121N|mint:P36018|ensemblfungi:YKR014C(gene)|ensemblfungi:YKR014C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0036258"(multivesicular body assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-SCE-6798695|reactome:R-SCE-8856828|reactome:R-SCE-8873719|reactome:R-SCE-8876198|reactome:R-SCE-983231 psi-mi:"MI:0469"(intact) crc64:30BB7FFF8D712FFD crc64:34AB2FFE38697261 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:quu5u+3WZxRJAobk3H2EERRUqKU559292 rogid:KZ9/F9Ilto2oDHiPHffIM2gcVnY559292 intact-crc:400C8A5CACAD4FB7|rigid:uMyIsN4grqXMHHFT3WpwAzrkp50 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32895 uniprotkb:P32895 intact:EBI-9869|uniprotkb:D6VX20|ensemblfungi:YKL181W intact:EBI-9869|uniprotkb:D6VX20|ensemblfungi:YKL181W psi-mi:kpr1_yeast(display_long)|uniprotkb:PPS1(gene name synonym)|uniprotkb:PRP1(gene name synonym)|uniprotkb:PRPS(gene name synonym)|uniprotkb:PRPS1(gene name synonym)|uniprotkb:YKL181W(locus name)|uniprotkb:PRS1(gene name)|psi-mi:PRS1(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 1(gene name synonym) psi-mi:kpr1_yeast(display_long)|uniprotkb:PPS1(gene name synonym)|uniprotkb:PRP1(gene name synonym)|uniprotkb:PRPS(gene name synonym)|uniprotkb:PRPS1(gene name synonym)|uniprotkb:YKL181W(locus name)|uniprotkb:PRS1(gene name)|psi-mi:PRS1(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323634|imex:IM-14275-884 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012740.1|sgd:S000001664|ensemblfungi:YKL181W(gene)|ensemblfungi:YKL181W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|dip:DIP-4857N|mint:P32895 refseq:NP_012740.1|sgd:S000001664|ensemblfungi:YKL181W(gene)|ensemblfungi:YKL181W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|dip:DIP-4857N|mint:P32895 psi-mi:"MI:0469"(intact) crc64:F3E93ACB25E703FF crc64:F3E93ACB25E703FF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ea45pOje4sjYrrU7ze4Af443yDk559292 rogid:Ea45pOje4sjYrrU7ze4Af443yDk559292 intact-crc:E43C84383AB8B799|rigid:VdgBK3SS0bD/LmbKBNr9Ebwhws8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32895 uniprotkb:P38063 intact:EBI-9869|uniprotkb:D6VX20|ensemblfungi:YKL181W intact:EBI-9882|uniprotkb:Q9HGQ6|ensemblfungi:YBL068W|uniprotkb:D6VPT3 psi-mi:kpr1_yeast(display_long)|uniprotkb:PPS1(gene name synonym)|uniprotkb:PRP1(gene name synonym)|uniprotkb:PRPS(gene name synonym)|uniprotkb:PRPS1(gene name synonym)|uniprotkb:YKL181W(locus name)|uniprotkb:PRS1(gene name)|psi-mi:PRS1(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 1(gene name synonym) psi-mi:kpr4_yeast(display_long)|uniprotkb:PRS4(gene name)|psi-mi:PRS4(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 4(gene name synonym)|uniprotkb:PRPS4(gene name synonym)|uniprotkb:YBL0619(orf name)|uniprotkb:YBL068W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323645|imex:IM-14275-885 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012740.1|sgd:S000001664|ensemblfungi:YKL181W(gene)|ensemblfungi:YKL181W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|dip:DIP-4857N|mint:P32895 sgd:S000000164|refseq:NP_009485.3|ensemblfungi:YBL068W(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|ensemblfungi:YBL068W_mRNA(transcript)|dip:DIP-3945N|mint:P38063 psi-mi:"MI:0469"(intact) crc64:F3E93ACB25E703FF crc64:B6335D5F1AB1A93C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ea45pOje4sjYrrU7ze4Af443yDk559292 rogid:elJfRIX/HKbgBlsUI0swFmGheuc559292 intact-crc:31C78C0EC6294FCC|rigid:JcLZMvF3mRWHRx6xuBTQJd+shq8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38620 uniprotkb:P32895 intact:EBI-9873|uniprotkb:D3DM06|ensemblfungi:YER099C intact:EBI-9869|uniprotkb:D6VX20|ensemblfungi:YKL181W psi-mi:kpr2_yeast(display_long)|uniprotkb:PRPS2(gene name synonym)|uniprotkb:PRS(gene name synonym)|uniprotkb:YER099C(locus name)|uniprotkb:PRS2(gene name)|psi-mi:PRS2(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 2(gene name synonym) psi-mi:kpr1_yeast(display_long)|uniprotkb:PPS1(gene name synonym)|uniprotkb:PRP1(gene name synonym)|uniprotkb:PRPS(gene name synonym)|uniprotkb:PRPS1(gene name synonym)|uniprotkb:YKL181W(locus name)|uniprotkb:PRS1(gene name)|psi-mi:PRS1(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323656|imex:IM-14275-886 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000901|ensemblfungi:YER099C(gene)|ensemblfungi:YER099C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|refseq:NP_011025.3|dip:DIP-1482N|mint:P38620 refseq:NP_012740.1|sgd:S000001664|ensemblfungi:YKL181W(gene)|ensemblfungi:YKL181W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|dip:DIP-4857N|mint:P32895 psi-mi:"MI:0469"(intact) crc64:8B970E98084F5D71 crc64:F3E93ACB25E703FF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:yDbNtDKkeTanVZwDAftGG9nhQCE559292 rogid:Ea45pOje4sjYrrU7ze4Af443yDk559292 intact-crc:E795B4DE0A76A071|rigid:H7yBj+nssqKKzMhSyeJb5jxCzso false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32895 uniprotkb:Q12265 intact:EBI-9869|uniprotkb:D6VX20|ensemblfungi:YKL181W intact:EBI-9886|ensemblfungi:YOL061W|uniprotkb:D6W206 psi-mi:kpr1_yeast(display_long)|uniprotkb:PPS1(gene name synonym)|uniprotkb:PRP1(gene name synonym)|uniprotkb:PRPS(gene name synonym)|uniprotkb:PRPS1(gene name synonym)|uniprotkb:YKL181W(locus name)|uniprotkb:PRS1(gene name)|psi-mi:PRS1(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 1(gene name synonym) psi-mi:kpr5_yeast(display_long)|uniprotkb:PRS5(gene name)|psi-mi:PRS5(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 5(gene name synonym)|uniprotkb:PRPS5(gene name synonym)|uniprotkb:O1213(orf name)|uniprotkb:YOL061W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323667|imex:IM-14275-887 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012740.1|sgd:S000001664|ensemblfungi:YKL181W(gene)|ensemblfungi:YKL181W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|dip:DIP-4857N|mint:P32895 refseq:NP_014580.1|sgd:S000005422|ensemblfungi:YOL061W(gene)|ensemblfungi:YOL061W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|dip:DIP-1532N|mint:Q12265 psi-mi:"MI:0469"(intact) crc64:F3E93ACB25E703FF crc64:75C948D40D58256D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ea45pOje4sjYrrU7ze4Af443yDk559292 rogid:vnGVKU7vl2NG7lgcrlTVSHYYQMI559292 intact-crc:DC39B0F7583E13FD|rigid:E6ZDydGcmO1F3IkDRGTJCJpw/58 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3E776 uniprotkb:P32906 intact:EBI-2042805|uniprotkb:D6VQQ2|ensemblfungi:YBR255C-A intact:EBI-11094|ensemblfungi:YJR131W|uniprotkb:D6VWU9 psi-mi:yb255_yeast(display_long)|uniprotkb:YBR255C-A(locus name) psi-mi:mns1_yeast(display_long)|uniprotkb:MNS1(gene name)|psi-mi:MNS1(display_short)|uniprotkb:YJR131W(locus name)|uniprotkb:J2110(orf name)|uniprotkb:ER alpha-1,2-mannosidase(gene name synonym)|uniprotkb:"Man(9)-alpha-mannosidase"(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323678|imex:IM-14275-888 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000007649|interpro:IPR038882|refseq:NP_116328.4|mint:Q3E776|ensemblfungi:YBR255C-A(gene)|ensemblfungi:YBR255C-A_mRNA(transcript)|go:"GO:0016021"(integral component of membrane) ensemblfungi:YJR131W(gene)|ensemblfungi:YJR131W_mRNA(transcript)|rcsb pdb:1G6I|go:"GO:0004571"(mannosyl-oligosaccharide 1,2-alpha-mannosidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006491"(N-glycan processing)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0035977"(protein deglycosylation involved in glycoprotein catabolic process)|interpro:IPR001382(Glycoside hydrolase, family 47)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR036026|rcsb pdb:1DL2|refseq:NP_012665.3|sgd:S000003892|mint:P32906|dip:DIP-1441N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:LHd4ToffLuVn2nuqg93EsoO8ouo559292 rogid:8067UxxGbS9V/K2jVAFoS8pHOhQ559292 intact-crc:9FFDDB4F9B791809|rigid:mKyhyvNTTVBJEkawTJnaXkImhMo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32906 uniprotkb:Q8TGU5 intact:EBI-11094|ensemblfungi:YJR131W|uniprotkb:D6VWU9 intact:EBI-2042814|uniprotkb:D6VQU1|ensemblfungi:YBR296C-A psi-mi:mns1_yeast(display_long)|uniprotkb:MNS1(gene name)|psi-mi:MNS1(display_short)|uniprotkb:YJR131W(locus name)|uniprotkb:J2110(orf name)|uniprotkb:ER alpha-1,2-mannosidase(gene name synonym)|uniprotkb:"Man(9)-alpha-mannosidase"(gene name synonym) psi-mi:yb296_yeast(display_long)|uniprotkb:YBR296C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323689|imex:IM-14275-889 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YJR131W(gene)|ensemblfungi:YJR131W_mRNA(transcript)|rcsb pdb:1G6I|go:"GO:0004571"(mannosyl-oligosaccharide 1,2-alpha-mannosidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006491"(N-glycan processing)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0035977"(protein deglycosylation involved in glycoprotein catabolic process)|interpro:IPR001382(Glycoside hydrolase, family 47)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR036026|rcsb pdb:1DL2|refseq:NP_012665.3|sgd:S000003892|mint:P32906|dip:DIP-1441N sgd:S000028605|refseq:NP_878055.3|mint:Q8TGU5|ensemblfungi:YBR296C-A(gene)|ensemblfungi:YBR296C-A_mRNA(transcript)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8067UxxGbS9V/K2jVAFoS8pHOhQ559292 rogid:DZubWD7lnwtea4Ne/bK1ITPFaJk559292 intact-crc:92229955772227AE|rigid:J1BvwjRB3Tfk4x1Q7Jx0oFQgdbs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32912 uniprotkb:P12868 intact:EBI-20232|uniprotkb:D6VTU3|ensemblfungi:YGL212W intact:EBI-6450|uniprotkb:D6W057|ensemblfungi:YMR231W psi-mi:vam7_yeast(display_long)|uniprotkb:VAM7(gene name)|psi-mi:VAM7(display_short)|uniprotkb:YGL212W(locus name) psi-mi:pep5_yeast(display_long)|uniprotkb:PEP5(gene name)|psi-mi:PEP5(display_short)|uniprotkb:END1(gene name synonym)|uniprotkb:Histone E3 ligase PEP5(gene name synonym)|uniprotkb:Vacuolar biogenesis protein END1(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 11(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 1(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 11(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 5(gene name synonym)|uniprotkb:VAM1(gene name synonym)|uniprotkb:VPL9(gene name synonym)|uniprotkb:VPS11(gene name synonym)|uniprotkb:VPT11(gene name synonym)|uniprotkb:YM9959.13(orf name)|uniprotkb:YMR231W(locus name)|uniprotkb:RING-type E3 ubiquitin transferase PEP5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323700|imex:IM-14275-890 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011303.1|sgd:S000003180|ensemblfungi:YGL212W(gene)|ensemblfungi:YGL212W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0031201"(SNARE complex)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0061909"(autophagosome-lysosome fusion)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001683(Phox-like)|interpro:IPR036871|rcsb pdb:1KMD|dip:DIP-1722N|mint:P32912 refseq:NP_013958.1|sgd:S000004844|mint:P12868|dip:DIP-4409N|ensemblfungi:YMR231W(gene)|ensemblfungi:YMR231W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0036205"(histone catabolic process)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0099022"(vesicle tethering)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322 psi-mi:"MI:0469"(intact) crc64:2F992AEC0ACBC8FE crc64:E5216AD3C285CF34 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RC40scMhwxxJHE4gke72JgkKeh4559292 rogid:xEGHUcsIIYJCmMvkniYtRd7XE+s559292 intact-crc:AB2A25FFBC9B04E7|rigid:MQxDvGZQPxazDJvDuZRqKlRn6Uo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32913 uniprotkb:P34110 intact:EBI-20366|uniprotkb:Q12279|uniprotkb:D6W2J0|ensemblfungi:YOR132W intact:EBI-20415|uniprotkb:D6VW33|ensemblfungi:YJL154C psi-mi:vps17_yeast(display_long)|uniprotkb:VPS17(gene name)|psi-mi:VPS17(display_short)|uniprotkb:PEP21(gene name synonym)|uniprotkb:YOR132W(locus name)|uniprotkb:O3314(orf name)|uniprotkb:YOR3314W(orf name)|uniprotkb:Carboxypeptidase Y-deficient protein 21(gene name synonym) psi-mi:vps35_yeast(display_long)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:Vacuolar protein-targeting protein 7(gene name synonym)|uniprotkb:VPT7(gene name synonym)|uniprotkb:J0580(orf name)|uniprotkb:YJL154C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323711|imex:IM-14275-891 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005658|refseq:NP_014775.3|ensemblfungi:YOR132W(gene)|ensemblfungi:YOR132W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR001683(Phox-like)|interpro:IPR014461(Vacuolar protein sorting-associated protein Vps17)|interpro:IPR027267|interpro:IPR036871|interpro:IPR037907|dip:DIP-1739N|mint:P32913 refseq:NP_012381.1|sgd:S000003690|ensemblfungi:YJL154C(gene)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1904377"(positive regulation of protein localization to cell periphery)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR042491|reactome:R-SCE-3238698|ensemblfungi:YJL154C_mRNA(transcript)|dip:DIP-1743N|mint:P34110 psi-mi:"MI:0469"(intact) crc64:C709968468144A50 crc64:DE1BC57B9DFB606E figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:X5nNIyX3T0PYprdyJaxVnc8RoR8559292 rogid:5KBi/lSF+BsMyg9ulP9eLCp2xCc559292 intact-crc:28234F74D765CCD1|rigid:se9RuRXrDe89wVOsPD38b6hdj2s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40335 uniprotkb:P32913 intact:EBI-20373|uniprotkb:D6VWC9|intact:EBI-3674163|uniprotkb:E9P910|ensemblfungi:YJL053W intact:EBI-20366|uniprotkb:Q12279|uniprotkb:D6W2J0|ensemblfungi:YOR132W psi-mi:pep8_yeast(display_long)|uniprotkb:PEP8(gene name)|psi-mi:PEP8(display_short)|uniprotkb:GRD6(gene name synonym)|uniprotkb:VPS26(gene name synonym)|uniprotkb:VPT4(gene name synonym)|uniprotkb:J1152(orf name)|uniprotkb:YJL053W(locus name)|uniprotkb:Vacuolar protein-targeting protein 4(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 26(gene name synonym) psi-mi:vps17_yeast(display_long)|uniprotkb:VPS17(gene name)|psi-mi:VPS17(display_short)|uniprotkb:PEP21(gene name synonym)|uniprotkb:YOR132W(locus name)|uniprotkb:O3314(orf name)|uniprotkb:YOR3314W(orf name)|uniprotkb:Carboxypeptidase Y-deficient protein 21(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323722|imex:IM-14275-892 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012482.1|sgd:S000003589|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0140318"(protein transporter activity)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR028934|reactome:R-SCE-3238698|ensemblfungi:YJL053W(gene)|ensemblfungi:YJL053W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|dip:DIP-4572N|mint:P40335 sgd:S000005658|refseq:NP_014775.3|ensemblfungi:YOR132W(gene)|ensemblfungi:YOR132W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR001683(Phox-like)|interpro:IPR014461(Vacuolar protein sorting-associated protein Vps17)|interpro:IPR027267|interpro:IPR036871|interpro:IPR037907|dip:DIP-1739N|mint:P32913 psi-mi:"MI:0469"(intact) crc64:40D15594E70A9B58 crc64:C709968468144A50 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mwZb20cO8nZl8hVUSRXAB5Varg0559292 rogid:X5nNIyX3T0PYprdyJaxVnc8RoR8559292 intact-crc:3E10DC664544E1E7|rigid:eJ3lYgrcRz3g3w51zNTTQuVB0/w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32913 uniprotkb:P40959 intact:EBI-20366|uniprotkb:Q12279|uniprotkb:D6W2J0|ensemblfungi:YOR132W intact:EBI-11636|ensemblfungi:YMR004W|uniprotkb:D6VZH9 psi-mi:vps17_yeast(display_long)|uniprotkb:VPS17(gene name)|psi-mi:VPS17(display_short)|uniprotkb:PEP21(gene name synonym)|uniprotkb:YOR132W(locus name)|uniprotkb:O3314(orf name)|uniprotkb:YOR3314W(orf name)|uniprotkb:Carboxypeptidase Y-deficient protein 21(gene name synonym) psi-mi:mvp1_yeast(display_long)|uniprotkb:MVP1(gene name)|psi-mi:MVP1(display_short)|uniprotkb:YM8270.06(orf name)|uniprotkb:YMR004W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323733|imex:IM-14275-893 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005658|refseq:NP_014775.3|ensemblfungi:YOR132W(gene)|ensemblfungi:YOR132W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR001683(Phox-like)|interpro:IPR014461(Vacuolar protein sorting-associated protein Vps17)|interpro:IPR027267|interpro:IPR036871|interpro:IPR037907|dip:DIP-1739N|mint:P32913 ensemblfungi:YMR004W(gene)|ensemblfungi:YMR004W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0016020"(membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001683(Phox-like)|interpro:IPR028662|interpro:IPR035704|interpro:IPR036871|rcsb pdb:6Q0X|refseq:NP_013717.1|sgd:S000004606|mint:P40959|dip:DIP-1764N psi-mi:"MI:0469"(intact) crc64:C709968468144A50 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:X5nNIyX3T0PYprdyJaxVnc8RoR8559292 rogid:3IrMPCYXP5yb2l52Uhu2DiEuNdI559292 intact-crc:8ED57D4F6696379C|rigid:dKW9rNo4wWk21UAMEWaqPE4A+UI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32913 uniprotkb:Q92331 intact:EBI-20366|uniprotkb:Q12279|uniprotkb:D6W2J0|ensemblfungi:YOR132W intact:EBI-20483|uniprotkb:Q08483|uniprotkb:D6W2D1|uniprotkb:E9P8U6|ensemblfungi:YOR069W psi-mi:vps17_yeast(display_long)|uniprotkb:VPS17(gene name)|psi-mi:VPS17(display_short)|uniprotkb:PEP21(gene name synonym)|uniprotkb:YOR132W(locus name)|uniprotkb:O3314(orf name)|uniprotkb:YOR3314W(orf name)|uniprotkb:Carboxypeptidase Y-deficient protein 21(gene name synonym) psi-mi:vps5_yeast(display_long)|uniprotkb:VPS5(gene name)|psi-mi:VPS5(display_short)|uniprotkb:GRD2(gene name synonym)|uniprotkb:PEP10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 5(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 10(gene name synonym)|uniprotkb:VPT5(gene name synonym)|uniprotkb:YOR29-20(orf name)|uniprotkb:YOR069W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323744|imex:IM-14275-894 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005658|refseq:NP_014775.3|ensemblfungi:YOR132W(gene)|ensemblfungi:YOR132W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR001683(Phox-like)|interpro:IPR014461(Vacuolar protein sorting-associated protein Vps17)|interpro:IPR027267|interpro:IPR036871|interpro:IPR037907|dip:DIP-1739N|mint:P32913 refseq:NP_014712.2|sgd:S000005595|ensemblfungi:YOR069W(gene)|ensemblfungi:YOR069W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0005768"(endosome)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|interpro:IPR001683(Phox-like)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028648|interpro:IPR035803|interpro:IPR036871|interpro:IPR037868|dip:DIP-1740N|mint:Q92331 psi-mi:"MI:0469"(intact) crc64:C709968468144A50 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:X5nNIyX3T0PYprdyJaxVnc8RoR8559292 rogid:5aPSkQUJV1sfIc9Ql+wMP74Y3QI559292 intact-crc:E53705602D49137B|rigid:7oteIkllY4V4dczAOKbHCabO1t0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21825 uniprotkb:P32915 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323755|imex:IM-14275-895 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 intact-crc:734426AC57F04FB8|rigid:9+6ckcR5B9lkz52FMc6dwoe1oPk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32939 uniprotkb:P32864 intact:EBI-29509|uniprotkb:D6VZH4|ensemblfungi:YML001W intact:EBI-14799|uniprotkb:Q06761|uniprotkb:D6W363|ensemblfungi:YOR370C psi-mi:ypt7_yeast(display_long)|uniprotkb:YPT7(gene name)|psi-mi:YPT7(display_short)|uniprotkb:VAM4(gene name synonym)|uniprotkb:Vacuolar morphology protein 4(gene name synonym)|uniprotkb:YM8270.02(orf name)|uniprotkb:YML001W(locus name) psi-mi:raep_yeast(display_long)|uniprotkb:YOR370C(locus name)|uniprotkb:MRS6(gene name)|psi-mi:MRS6(display_short)|uniprotkb:MSI4(gene name synonym)|uniprotkb:Rab escort protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323766|imex:IM-14275-896 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013713.1|sgd:S000004460|dip:DIP-1735N|mint:P32939|ensemblfungi:YML001W(gene)|ensemblfungi:YML001W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1990816"(vacuole-mitochondrion membrane contact site)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1KY2|rcsb pdb:1KY3|rcsb pdb:4PHF|rcsb pdb:4PHG|rcsb pdb:4PHH|reactome:R-SCE-6798695|reactome:R-SCE-8854214|reactome:R-SCE-8873719|reactome:R-SCE-8876198|reactome:R-SCE-9013405|reactome:R-SCE-9013406 refseq:NP_015015.1|sgd:S000005897|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005968"(Rab-protein geranylgeranyltransferase complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR017230(Rab protein geranylgeranyltransferase, component A, fungi)|interpro:IPR018203|interpro:IPR036188|reactome:R-SCE-6803205|reactome:R-SCE-8873719|reactome:R-SCE-8876198|ensemblfungi:YOR370C(gene)|ensemblfungi:YOR370C_mRNA(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|dip:DIP-2246N|mint:P32864 psi-mi:"MI:0469"(intact) crc64:0E2B72BDA7F7CEE5 crc64:30BB7FFF8D712FFD figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZR2uZTxqTXnSamelDJbMoEI2af8559292 rogid:quu5u+3WZxRJAobk3H2EERRUqKU559292 intact-crc:F7EDEE5B6D445F10|rigid:iIaZB24YotcGOGkDiTvMuVXKeOA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39958 uniprotkb:P32939 intact:EBI-7517|uniprotkb:D3DM41|ensemblfungi:YER136W intact:EBI-29509|uniprotkb:D6VZH4|ensemblfungi:YML001W psi-mi:gdi1_yeast(display_long)|uniprotkb:YER136W(locus name)|uniprotkb:GDI1(gene name)|psi-mi:GDI1(display_short)|uniprotkb:SEC19(gene name synonym)|uniprotkb:Secretory pathway GDP dissociation inhibitor(gene name synonym) psi-mi:ypt7_yeast(display_long)|uniprotkb:YPT7(gene name)|psi-mi:YPT7(display_short)|uniprotkb:VAM4(gene name synonym)|uniprotkb:Vacuolar morphology protein 4(gene name synonym)|uniprotkb:YM8270.02(orf name)|uniprotkb:YML001W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323777|imex:IM-14275-897 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011062.1|sgd:S000000938|mint:P39958|dip:DIP-785N|ensemblfungi:YER136W(gene)|ensemblfungi:YER136W_mRNA(transcript)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|rcsb pdb:1UKV|rcsb pdb:2BCG|rcsb pdb:3CPH|rcsb pdb:3CPI|rcsb pdb:3CPJ|reactome:R-SCE-6798695|reactome:R-SCE-8876198 refseq:NP_013713.1|sgd:S000004460|dip:DIP-1735N|mint:P32939|ensemblfungi:YML001W(gene)|ensemblfungi:YML001W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1990816"(vacuole-mitochondrion membrane contact site)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1KY2|rcsb pdb:1KY3|rcsb pdb:4PHF|rcsb pdb:4PHG|rcsb pdb:4PHH|reactome:R-SCE-6798695|reactome:R-SCE-8854214|reactome:R-SCE-8873719|reactome:R-SCE-8876198|reactome:R-SCE-9013405|reactome:R-SCE-9013406 psi-mi:"MI:0469"(intact) crc64:48CF8D45FC031772 crc64:0E2B72BDA7F7CEE5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AkWsG1VUBGxajiAMw0e0mOljZ6s559292 rogid:ZR2uZTxqTXnSamelDJbMoEI2af8559292 intact-crc:22659151345A4E94|rigid:Ft6NC6o1oHlYMiU/B9EzQlhGOng false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17555 uniprotkb:P33204 intact:EBI-4024|uniprotkb:D6W144|ensemblfungi:YNL138W intact:EBI-2757|uniprotkb:D6VXS3|ensemblfungi:YKL013C psi-mi:cap_yeast(display_long)|uniprotkb:SRV2(gene name)|psi-mi:SRV2(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:YNL138W(locus name)|uniprotkb:N1210(orf name)|uniprotkb:N1838(orf name) psi-mi:arpc4_yeast(display_long)|uniprotkb:ARC19(gene name)|psi-mi:ARC19(display_short)|uniprotkb:YKL013C(locus name)|uniprotkb:YKL166(orf name)|uniprotkb:Arp2/3 complex 20 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323788|imex:IM-14275-898 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014261.1|sgd:S000005082|dip:DIP-77N|ensemblfungi:YNL138W(gene)|ensemblfungi:YNL138W_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007265"(Ras protein signal transduction)|mint:P17555|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0051014"(actin filament severing)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|rcsb pdb:1K4Z|rcsb pdb:1KQ5|reactome:R-SCE-6798695 refseq:NP_012912.1|sgd:S000001496|dip:DIP-1819N|mint:P33204|ensemblfungi:YKL013C(gene)|ensemblfungi:YKL013C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:0EB4D41205E2D464 crc64:B80CBD6642E39C1C figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3Fs9g+L5RnbkqYThVpOvSFrZoJ8559292 rogid:wscMsqBK/3Rsah+2vbE3REyYhhg559292 intact-crc:2BA7D6CA15705631|rigid:NW3wJkRsq83zFpin/kAq9nNM4dM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33204 uniprotkb:P37370 intact:EBI-2757|uniprotkb:D6VXS3|ensemblfungi:YKL013C intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C psi-mi:arpc4_yeast(display_long)|uniprotkb:ARC19(gene name)|psi-mi:ARC19(display_short)|uniprotkb:YKL013C(locus name)|uniprotkb:YKL166(orf name)|uniprotkb:Arp2/3 complex 20 kDa(gene name synonym) psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323799|imex:IM-14275-899 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012912.1|sgd:S000001496|dip:DIP-1819N|mint:P33204|ensemblfungi:YKL013C(gene)|ensemblfungi:YKL013C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370 psi-mi:"MI:0469"(intact) crc64:B80CBD6642E39C1C crc64:24C7522D5B1CA1C8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wscMsqBK/3Rsah+2vbE3REyYhhg559292 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 intact-crc:2054D1A2E8114C3F|rigid:Ms3kfTeoDH/y0fkNIE3YvT5otAE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38328 uniprotkb:P33204 intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C intact:EBI-2757|uniprotkb:D6VXS3|ensemblfungi:YKL013C psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:arpc4_yeast(display_long)|uniprotkb:ARC19(gene name)|psi-mi:ARC19(display_short)|uniprotkb:YKL013C(locus name)|uniprotkb:YKL166(orf name)|uniprotkb:Arp2/3 complex 20 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323810|imex:IM-14275-900 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 refseq:NP_012912.1|sgd:S000001496|dip:DIP-1819N|mint:P33204|ensemblfungi:YKL013C(gene)|ensemblfungi:YKL013C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:D75C6BB8EC35EEDF crc64:B80CBD6642E39C1C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 rogid:wscMsqBK/3Rsah+2vbE3REyYhhg559292 intact-crc:9A7BE9D79E695869|rigid:ZneRk9qKcTomL6x48DRIkNNEWk4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12446 uniprotkb:P33204 intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W intact:EBI-2757|uniprotkb:D6VXS3|ensemblfungi:YKL013C psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name) psi-mi:arpc4_yeast(display_long)|uniprotkb:ARC19(gene name)|psi-mi:ARC19(display_short)|uniprotkb:YKL013C(locus name)|uniprotkb:YKL166(orf name)|uniprotkb:Arp2/3 complex 20 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323821|imex:IM-14275-901 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446 refseq:NP_012912.1|sgd:S000001496|dip:DIP-1819N|mint:P33204|ensemblfungi:YKL013C(gene)|ensemblfungi:YKL013C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:4488355563AA2645 crc64:B80CBD6642E39C1C figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292 rogid:wscMsqBK/3Rsah+2vbE3REyYhhg559292 intact-crc:3F9989A8DCBE7D1F|rigid:Ioti7upMZ4xJkMWkCnA3blhSK9A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33204 uniprotkb:Q6Q5K6 intact:EBI-2757|uniprotkb:D6VXS3|ensemblfungi:YKL013C intact:EBI-392766|ensemblfungi:YML058W-A|uniprotkb:D6VZB5 psi-mi:arpc4_yeast(display_long)|uniprotkb:ARC19(gene name)|psi-mi:ARC19(display_short)|uniprotkb:YKL013C(locus name)|uniprotkb:YKL166(orf name)|uniprotkb:Arp2/3 complex 20 kDa(gene name synonym) psi-mi:hug1_yeast(display_long)|uniprotkb:HUG1(gene name)|psi-mi:HUG1(display_short)|uniprotkb:YML058W-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323832|imex:IM-14275-902 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012912.1|sgd:S000001496|dip:DIP-1819N|mint:P33204|ensemblfungi:YKL013C(gene)|ensemblfungi:YKL013C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 ensemblfungi:YML058W-A(gene)|ensemblfungi:YML058W-A_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:1905117"(regulation of ribonucleoside-diphosphate reductase activity)|go:"GO:1990846"(ribonucleoside-diphosphate reductase inhibitor activity)|sgd:S000007472|refseq:NP_219498.1|mint:Q6Q5K6 psi-mi:"MI:0469"(intact) crc64:B80CBD6642E39C1C - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wscMsqBK/3Rsah+2vbE3REyYhhg559292 rogid:x+quBrnP+8yql7JGQ1NK4j5ubbw559292 intact-crc:9427AD7AE927B713|rigid:kozY7aluHQVCYSG6mSmggmCIhag false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33297 uniprotkb:P33298 intact:EBI-13920|uniprotkb:D6W2H6|ensemblfungi:YOR117W intact:EBI-13905|ensemblfungi:YDR394W|uniprotkb:D6VT28 psi-mi:prs6a_yeast(display_long)|uniprotkb:RPT5(gene name)|psi-mi:RPT5(display_short)|uniprotkb:YTA1(gene name synonym)|uniprotkb:YOR117W(locus name)|uniprotkb:O3258(orf name)|uniprotkb:YOR3258W(orf name)|uniprotkb:Tat-binding protein homolog 1(gene name synonym) psi-mi:prs6b_yeast(display_long)|uniprotkb:RPT3(gene name)|psi-mi:RPT3(display_short)|uniprotkb:YNT1(gene name synonym)|uniprotkb:YTA2(gene name synonym)|uniprotkb:YDR394W(locus name)|uniprotkb:D9509.14(orf name)|uniprotkb:Protein YNT1(gene name synonym)|uniprotkb:Tat-binding homolog 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323843|imex:IM-14275-903 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005643|rcsb pdb:3WHL|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|rcsb pdb:3WHK|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|ensemblfungi:YOR117W(gene)|ensemblfungi:YOR117W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|refseq:NP_014760.3|mint:P33297|dip:DIP-1590N sgd:S000002802|ensemblfungi:YDR394W(gene)|ensemblfungi:YDR394W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|refseq:NP_010682.3|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|rcsb pdb:2DZN|rcsb pdb:2DZO|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33298|dip:DIP-1587N|interpro:IPR003960(AAA ATPase, conserved site) psi-mi:"MI:0469"(intact) crc64:C215422033FCE830 crc64:E12F0995A60732BD figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jsQE3SjBA0ZZcysuLgFe/5M6pOc559292 rogid:teaQwAlS0ruTNKbLkX7kP4lkn7o559292 intact-crc:1665CC3A2B968550|rigid:B1zbWAI+Hdvx1AZVijzQQJQHozM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33297 uniprotkb:P33299 intact:EBI-13920|uniprotkb:D6W2H6|ensemblfungi:YOR117W intact:EBI-13910|uniprotkb:D6VX51|ensemblfungi:YKL145W psi-mi:prs6a_yeast(display_long)|uniprotkb:RPT5(gene name)|psi-mi:RPT5(display_short)|uniprotkb:YTA1(gene name synonym)|uniprotkb:YOR117W(locus name)|uniprotkb:O3258(orf name)|uniprotkb:YOR3258W(orf name)|uniprotkb:Tat-binding protein homolog 1(gene name synonym) psi-mi:prs7_yeast(display_long)|uniprotkb:YKL145W(locus name)|uniprotkb:RPT1(gene name)|psi-mi:RPT1(display_short)|uniprotkb:CIM5(gene name synonym)|uniprotkb:YTA3(gene name synonym)|uniprotkb:Protein CIM5(gene name synonym)|uniprotkb:Tat-binding homolog 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323854|imex:IM-14275-904 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005643|rcsb pdb:3WHL|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|rcsb pdb:3WHK|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|ensemblfungi:YOR117W(gene)|ensemblfungi:YOR117W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|refseq:NP_014760.3|mint:P33297|dip:DIP-1590N refseq:NP_012777.1|sgd:S000001628|ensemblfungi:YKL145W(gene)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|ensemblfungi:YKL145W_mRNA(transcript)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0005524"(ATP binding)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|go:"GO:0005634"(nucleus)|rcsb pdb:3VLF|rcsb pdb:4A3V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4JPO|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|rcsb pdb:5A5B|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:5MP9|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|rcsb pdb:6EF3|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33299|dip:DIP-2883N psi-mi:"MI:0469"(intact) crc64:C215422033FCE830 crc64:8454BBC9D549EC5C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jsQE3SjBA0ZZcysuLgFe/5M6pOc559292 rogid:8XXo53yZ1KevHObtYWABeFr0hWo559292 intact-crc:89DCC71C0E62DB04|rigid:8U3xT6hs4uqcGgQABYLvvouccCo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38764 uniprotkb:P33297 intact:EBI-15913|uniprotkb:D3DKX4|ensemblfungi:YHR027C intact:EBI-13920|uniprotkb:D6W2H6|ensemblfungi:YOR117W psi-mi:rpn1_yeast(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:HRD2(gene name synonym)|uniprotkb:NAS1(gene name synonym)|uniprotkb:RPD1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 1(gene name synonym)|uniprotkb:HMG-CoA reductase degradation protein 2(gene name synonym)|uniprotkb:YHR027C(locus name) psi-mi:prs6a_yeast(display_long)|uniprotkb:RPT5(gene name)|psi-mi:RPT5(display_short)|uniprotkb:YTA1(gene name synonym)|uniprotkb:YOR117W(locus name)|uniprotkb:O3258(orf name)|uniprotkb:YOR3258W(orf name)|uniprotkb:Tat-binding protein homolog 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323865|imex:IM-14275-905 author score:98.11 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011892.1|sgd:S000001069|ensemblfungi:YHR027C(gene)|ensemblfungi:YHR027C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|rcsb pdb:2N3T|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBW|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|rcsb pdb:6FVU|reactome:R-SCE-983168|rcsb pdb:6FVV|rcsb pdb:6FVW|dip:DIP-2876N|mint:P38764 sgd:S000005643|rcsb pdb:3WHL|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|rcsb pdb:3WHK|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|ensemblfungi:YOR117W(gene)|ensemblfungi:YOR117W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|refseq:NP_014760.3|mint:P33297|dip:DIP-1590N psi-mi:"MI:0469"(intact) crc64:B77954F4A998BA7C crc64:C215422033FCE830 figure legend:tables S3 and S4|author-confidence:98.11|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:KZvwC6NNLC/jEW8wXPq2z+EFukY559292 rogid:jsQE3SjBA0ZZcysuLgFe/5M6pOc559292 intact-crc:9604B70B757988A9|rigid:yu3pNpqPTeME6ojbWEFLQWnzkjk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40327 uniprotkb:P33297 intact:EBI-13901|uniprotkb:D6VRY1|ensemblfungi:YDL007W intact:EBI-13920|uniprotkb:D6W2H6|ensemblfungi:YOR117W psi-mi:prs4_yeast(display_long)|uniprotkb:RPT2(gene name)|psi-mi:RPT2(display_short)|uniprotkb:YHS4(gene name synonym)|uniprotkb:YTA5(gene name synonym)|uniprotkb:YDL007W(locus name)|uniprotkb:D2920(orf name)|uniprotkb:Tat-binding homolog 5(gene name synonym) psi-mi:prs6a_yeast(display_long)|uniprotkb:RPT5(gene name)|psi-mi:RPT5(display_short)|uniprotkb:YTA1(gene name synonym)|uniprotkb:YOR117W(locus name)|uniprotkb:O3258(orf name)|uniprotkb:YOR3258W(orf name)|uniprotkb:Tat-binding protein homolog 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323876|imex:IM-14275-906 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010277.1|sgd:S000002165|ensemblfungi:YDL007W(gene)|ensemblfungi:YDL007W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0034629"|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:4CR2|rcsb pdb:3JCP|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-532668|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P40327|dip:DIP-6282N sgd:S000005643|rcsb pdb:3WHL|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|rcsb pdb:3WHK|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|ensemblfungi:YOR117W(gene)|ensemblfungi:YOR117W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|refseq:NP_014760.3|mint:P33297|dip:DIP-1590N psi-mi:"MI:0469"(intact) crc64:EB735354C3A0EBD4 crc64:C215422033FCE830 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nSy31Q+snoZMZrFmXscv8/HQYk0559292 rogid:jsQE3SjBA0ZZcysuLgFe/5M6pOc559292 intact-crc:C6813752F8AC2C21|rigid:MtriftJsPn0FGCqglhC+0Ldw1LE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33297 uniprotkb:P53549 intact:EBI-13920|uniprotkb:D6W2H6|ensemblfungi:YOR117W intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C psi-mi:prs6a_yeast(display_long)|uniprotkb:RPT5(gene name)|psi-mi:RPT5(display_short)|uniprotkb:YTA1(gene name synonym)|uniprotkb:YOR117W(locus name)|uniprotkb:O3258(orf name)|uniprotkb:YOR3258W(orf name)|uniprotkb:Tat-binding protein homolog 1(gene name synonym) psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323887|imex:IM-14275-907 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005643|rcsb pdb:3WHL|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|rcsb pdb:3WHK|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|ensemblfungi:YOR117W(gene)|ensemblfungi:YOR117W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|refseq:NP_014760.3|mint:P33297|dip:DIP-1590N sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 psi-mi:"MI:0469"(intact) crc64:C215422033FCE830 crc64:0EA42A599E2B2E2A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jsQE3SjBA0ZZcysuLgFe/5M6pOc559292 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 intact-crc:0FD74FAA719B9FC8|rigid:jzobsaB/fyUuayz6QIPIWtAeeYI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01939 uniprotkb:P33297 intact:EBI-13914|ensemblfungi:YGL048C|uniprotkb:D6VU92 intact:EBI-13920|uniprotkb:D6W2H6|ensemblfungi:YOR117W psi-mi:prs8_yeast(display_long)|uniprotkb:TBPY(gene name synonym)|uniprotkb:TBY1(gene name synonym)|uniprotkb:YGL048C(locus name)|uniprotkb:RPT6(gene name)|psi-mi:RPT6(display_short)|uniprotkb:CIM3(gene name synonym)|uniprotkb:CRL3(gene name synonym)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Protein SUG1(gene name synonym)|uniprotkb:Protein CIM3(gene name synonym)|uniprotkb:Tat-binding protein TBY1(gene name synonym) psi-mi:prs6a_yeast(display_long)|uniprotkb:RPT5(gene name)|psi-mi:RPT5(display_short)|uniprotkb:YTA1(gene name synonym)|uniprotkb:YOR117W(locus name)|uniprotkb:O3258(orf name)|uniprotkb:YOR3258W(orf name)|uniprotkb:Tat-binding protein homolog 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323898|imex:IM-14275-908 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-8854050|ensemblfungi:YGL048C(gene)|ensemblfungi:YGL048C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011467.1|sgd:S000003016|mint:Q01939|dip:DIP-979N sgd:S000005643|rcsb pdb:3WHL|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|rcsb pdb:3WHK|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|ensemblfungi:YOR117W(gene)|ensemblfungi:YOR117W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|refseq:NP_014760.3|mint:P33297|dip:DIP-1590N psi-mi:"MI:0469"(intact) crc64:9C59E92A0794F60F crc64:C215422033FCE830 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lvkwNLqTeoit17Ax4mP0+WiGzsY559292 rogid:jsQE3SjBA0ZZcysuLgFe/5M6pOc559292 intact-crc:7438ECA3F4DF38DE|rigid:aelxxVFjit5loxb4Ng/+JgRsJz8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33297 uniprotkb:P33299 intact:EBI-13920|uniprotkb:D6W2H6|ensemblfungi:YOR117W intact:EBI-13910|uniprotkb:D6VX51|ensemblfungi:YKL145W psi-mi:prs6a_yeast(display_long)|uniprotkb:RPT5(gene name)|psi-mi:RPT5(display_short)|uniprotkb:YTA1(gene name synonym)|uniprotkb:YOR117W(locus name)|uniprotkb:O3258(orf name)|uniprotkb:YOR3258W(orf name)|uniprotkb:Tat-binding protein homolog 1(gene name synonym) psi-mi:prs7_yeast(display_long)|uniprotkb:YKL145W(locus name)|uniprotkb:RPT1(gene name)|psi-mi:RPT1(display_short)|uniprotkb:CIM5(gene name synonym)|uniprotkb:YTA3(gene name synonym)|uniprotkb:Protein CIM5(gene name synonym)|uniprotkb:Tat-binding homolog 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323909|imex:IM-14275-909 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005643|rcsb pdb:3WHL|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|rcsb pdb:3WHK|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|ensemblfungi:YOR117W(gene)|ensemblfungi:YOR117W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|refseq:NP_014760.3|mint:P33297|dip:DIP-1590N refseq:NP_012777.1|sgd:S000001628|ensemblfungi:YKL145W(gene)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|ensemblfungi:YKL145W_mRNA(transcript)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0005524"(ATP binding)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|go:"GO:0005634"(nucleus)|rcsb pdb:3VLF|rcsb pdb:4A3V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4JPO|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|rcsb pdb:5A5B|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:5MP9|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|rcsb pdb:6EF3|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33299|dip:DIP-2883N psi-mi:"MI:0469"(intact) crc64:C215422033FCE830 crc64:8454BBC9D549EC5C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jsQE3SjBA0ZZcysuLgFe/5M6pOc559292 rogid:8XXo53yZ1KevHObtYWABeFr0hWo559292 intact-crc:081D3D24100FEF8A|rigid:8U3xT6hs4uqcGgQABYLvvouccCo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33299 uniprotkb:P33298 intact:EBI-13910|uniprotkb:D6VX51|ensemblfungi:YKL145W intact:EBI-13905|ensemblfungi:YDR394W|uniprotkb:D6VT28 psi-mi:prs7_yeast(display_long)|uniprotkb:YKL145W(locus name)|uniprotkb:RPT1(gene name)|psi-mi:RPT1(display_short)|uniprotkb:CIM5(gene name synonym)|uniprotkb:YTA3(gene name synonym)|uniprotkb:Protein CIM5(gene name synonym)|uniprotkb:Tat-binding homolog 3(gene name synonym) psi-mi:prs6b_yeast(display_long)|uniprotkb:RPT3(gene name)|psi-mi:RPT3(display_short)|uniprotkb:YNT1(gene name synonym)|uniprotkb:YTA2(gene name synonym)|uniprotkb:YDR394W(locus name)|uniprotkb:D9509.14(orf name)|uniprotkb:Protein YNT1(gene name synonym)|uniprotkb:Tat-binding homolog 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323920|imex:IM-14275-910 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012777.1|sgd:S000001628|ensemblfungi:YKL145W(gene)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|ensemblfungi:YKL145W_mRNA(transcript)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0005524"(ATP binding)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|go:"GO:0005634"(nucleus)|rcsb pdb:3VLF|rcsb pdb:4A3V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4JPO|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|rcsb pdb:5A5B|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:5MP9|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|rcsb pdb:6EF3|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33299|dip:DIP-2883N sgd:S000002802|ensemblfungi:YDR394W(gene)|ensemblfungi:YDR394W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|refseq:NP_010682.3|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|rcsb pdb:2DZN|rcsb pdb:2DZO|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33298|dip:DIP-1587N|interpro:IPR003960(AAA ATPase, conserved site) psi-mi:"MI:0469"(intact) crc64:8454BBC9D549EC5C crc64:E12F0995A60732BD figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8XXo53yZ1KevHObtYWABeFr0hWo559292 rogid:teaQwAlS0ruTNKbLkX7kP4lkn7o559292 intact-crc:071D3D1EC9AFE454|rigid:6vUwwwL+aVwPrT14+YwXP8gSYD8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33299 uniprotkb:P38764 intact:EBI-13910|uniprotkb:D6VX51|ensemblfungi:YKL145W intact:EBI-15913|uniprotkb:D3DKX4|ensemblfungi:YHR027C psi-mi:prs7_yeast(display_long)|uniprotkb:YKL145W(locus name)|uniprotkb:RPT1(gene name)|psi-mi:RPT1(display_short)|uniprotkb:CIM5(gene name synonym)|uniprotkb:YTA3(gene name synonym)|uniprotkb:Protein CIM5(gene name synonym)|uniprotkb:Tat-binding homolog 3(gene name synonym) psi-mi:rpn1_yeast(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:HRD2(gene name synonym)|uniprotkb:NAS1(gene name synonym)|uniprotkb:RPD1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 1(gene name synonym)|uniprotkb:HMG-CoA reductase degradation protein 2(gene name synonym)|uniprotkb:YHR027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323931|imex:IM-14275-911 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012777.1|sgd:S000001628|ensemblfungi:YKL145W(gene)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|ensemblfungi:YKL145W_mRNA(transcript)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0005524"(ATP binding)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|go:"GO:0005634"(nucleus)|rcsb pdb:3VLF|rcsb pdb:4A3V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4JPO|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|rcsb pdb:5A5B|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:5MP9|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|rcsb pdb:6EF3|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33299|dip:DIP-2883N refseq:NP_011892.1|sgd:S000001069|ensemblfungi:YHR027C(gene)|ensemblfungi:YHR027C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|rcsb pdb:2N3T|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBW|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|rcsb pdb:6FVU|reactome:R-SCE-983168|rcsb pdb:6FVV|rcsb pdb:6FVW|dip:DIP-2876N|mint:P38764 psi-mi:"MI:0469"(intact) crc64:8454BBC9D549EC5C crc64:B77954F4A998BA7C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8XXo53yZ1KevHObtYWABeFr0hWo559292 rogid:KZvwC6NNLC/jEW8wXPq2z+EFukY559292 intact-crc:9805068510101B35|rigid:IctTINCRjGZ3Y9UudyIR3e9l0lc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40327 uniprotkb:P33299 intact:EBI-13901|uniprotkb:D6VRY1|ensemblfungi:YDL007W intact:EBI-13910|uniprotkb:D6VX51|ensemblfungi:YKL145W psi-mi:prs4_yeast(display_long)|uniprotkb:RPT2(gene name)|psi-mi:RPT2(display_short)|uniprotkb:YHS4(gene name synonym)|uniprotkb:YTA5(gene name synonym)|uniprotkb:YDL007W(locus name)|uniprotkb:D2920(orf name)|uniprotkb:Tat-binding homolog 5(gene name synonym) psi-mi:prs7_yeast(display_long)|uniprotkb:YKL145W(locus name)|uniprotkb:RPT1(gene name)|psi-mi:RPT1(display_short)|uniprotkb:CIM5(gene name synonym)|uniprotkb:YTA3(gene name synonym)|uniprotkb:Protein CIM5(gene name synonym)|uniprotkb:Tat-binding homolog 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323942|imex:IM-14275-912 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010277.1|sgd:S000002165|ensemblfungi:YDL007W(gene)|ensemblfungi:YDL007W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0034629"|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:4CR2|rcsb pdb:3JCP|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-532668|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P40327|dip:DIP-6282N refseq:NP_012777.1|sgd:S000001628|ensemblfungi:YKL145W(gene)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|ensemblfungi:YKL145W_mRNA(transcript)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0005524"(ATP binding)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|go:"GO:0005634"(nucleus)|rcsb pdb:3VLF|rcsb pdb:4A3V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4JPO|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|rcsb pdb:5A5B|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:5MP9|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|rcsb pdb:6EF3|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33299|dip:DIP-2883N psi-mi:"MI:0469"(intact) crc64:EB735354C3A0EBD4 crc64:8454BBC9D549EC5C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nSy31Q+snoZMZrFmXscv8/HQYk0559292 rogid:8XXo53yZ1KevHObtYWABeFr0hWo559292 intact-crc:C881376C9C75BFBD|rigid:cPZi5DOlmDNw8dMvq3+gaP71kpA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P33299 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-13910|uniprotkb:D6VX51|ensemblfungi:YKL145W psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:prs7_yeast(display_long)|uniprotkb:YKL145W(locus name)|uniprotkb:RPT1(gene name)|psi-mi:RPT1(display_short)|uniprotkb:CIM5(gene name synonym)|uniprotkb:YTA3(gene name synonym)|uniprotkb:Protein CIM5(gene name synonym)|uniprotkb:Tat-binding homolog 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323953|imex:IM-14275-913 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 refseq:NP_012777.1|sgd:S000001628|ensemblfungi:YKL145W(gene)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|ensemblfungi:YKL145W_mRNA(transcript)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0005524"(ATP binding)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|go:"GO:0005634"(nucleus)|rcsb pdb:3VLF|rcsb pdb:4A3V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4JPO|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|rcsb pdb:5A5B|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:5MP9|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|rcsb pdb:6EF3|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33299|dip:DIP-2883N psi-mi:"MI:0469"(intact) crc64:0EA42A599E2B2E2A crc64:8454BBC9D549EC5C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:8XXo53yZ1KevHObtYWABeFr0hWo559292 intact-crc:01D74F9415420C54|rigid:b/+Xe3Dki9Xecn4RBBHN02ACZVc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33299 uniprotkb:Q01939 intact:EBI-13910|uniprotkb:D6VX51|ensemblfungi:YKL145W intact:EBI-13914|ensemblfungi:YGL048C|uniprotkb:D6VU92 psi-mi:prs7_yeast(display_long)|uniprotkb:YKL145W(locus name)|uniprotkb:RPT1(gene name)|psi-mi:RPT1(display_short)|uniprotkb:CIM5(gene name synonym)|uniprotkb:YTA3(gene name synonym)|uniprotkb:Protein CIM5(gene name synonym)|uniprotkb:Tat-binding homolog 3(gene name synonym) psi-mi:prs8_yeast(display_long)|uniprotkb:TBPY(gene name synonym)|uniprotkb:TBY1(gene name synonym)|uniprotkb:YGL048C(locus name)|uniprotkb:RPT6(gene name)|psi-mi:RPT6(display_short)|uniprotkb:CIM3(gene name synonym)|uniprotkb:CRL3(gene name synonym)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Protein SUG1(gene name synonym)|uniprotkb:Protein CIM3(gene name synonym)|uniprotkb:Tat-binding protein TBY1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323964|imex:IM-14275-914 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012777.1|sgd:S000001628|ensemblfungi:YKL145W(gene)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|ensemblfungi:YKL145W_mRNA(transcript)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0005524"(ATP binding)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|go:"GO:0005634"(nucleus)|rcsb pdb:3VLF|rcsb pdb:4A3V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4JPO|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|rcsb pdb:5A5B|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:5MP9|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|rcsb pdb:6EF3|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33299|dip:DIP-2883N go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-8854050|ensemblfungi:YGL048C(gene)|ensemblfungi:YGL048C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011467.1|sgd:S000003016|mint:Q01939|dip:DIP-979N psi-mi:"MI:0469"(intact) crc64:8454BBC9D549EC5C crc64:9C59E92A0794F60F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8XXo53yZ1KevHObtYWABeFr0hWo559292 rogid:lvkwNLqTeoit17Ax4mP0+WiGzsY559292 intact-crc:7A38EC9D9006AB42|rigid:Eacn17PqGd75u1Gw9o/Eqcu1NHc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41810 uniprotkb:P33300 intact:EBI-4869|uniprotkb:Q03779|uniprotkb:D6VSL9|ensemblfungi:YDR238C intact:EBI-18569|ensemblfungi:YPL057C|uniprotkb:D6W3V7 psi-mi:copb_yeast(display_long)|uniprotkb:SEC26(gene name)|psi-mi:SEC26(display_short)|uniprotkb:YDR238C(locus name)|uniprotkb:YD8419.05C(orf name)|uniprotkb:Beta-coat protein(gene name synonym) psi-mi:sur1_yeast(display_long)|uniprotkb:SUR1(gene name)|psi-mi:SUR1(display_short)|uniprotkb:YPL057C(locus name)|uniprotkb:BCL21(gene name synonym)|uniprotkb:CSG1(gene name synonym)|uniprotkb:LPE15(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323975|imex:IM-14275-915 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002646|refseq:NP_010524.3|dip:DIP-6467N|mint:P41810|ensemblfungi:YDR238C(gene)|ensemblfungi:YDR238C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|reactome:R-SCE-6798695|reactome:R-SCE-6807878|reactome:R-SCE-6811434 ensemblfungi:YPL057C(gene)|ensemblfungi:YPL057C_mRNA(transcript)|go:"GO:0000030"(mannosyltransferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0006675"(mannosyl-inositol phosphorylceramide metabolic process)|go:"GO:0006688"(glycosphingolipid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0051999"(mannosyl-inositol phosphorylceramide biosynthetic process)|interpro:IPR007577(Glycosyltransferase sugar-binding region containing DXD motif)|interpro:IPR029044|refseq:NP_015268.1|sgd:S000005978|dip:DIP-4557N|mint:P33300 psi-mi:"MI:0469"(intact) crc64:885420DB026BCFA3 crc64:5A9AAB5F9A4069E3 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZfLp1BUmvVuTiXn7/Zbf/3m6VtE559292 rogid:EJcMJxgSg3KmU6/RI3fAbMFCu9M559292 intact-crc:D20EE0FE85610D1B|rigid:ZEpEJR4CBG67lbkJpxJs1euNI4c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43621 uniprotkb:P33300 intact:EBI-4876|uniprotkb:D6VTT4|ensemblfungi:YFR051C intact:EBI-18569|ensemblfungi:YPL057C|uniprotkb:D6W3V7 psi-mi:copd_yeast(display_long)|uniprotkb:RET2(gene name)|psi-mi:RET2(display_short)|uniprotkb:YFR051C(locus name)|uniprotkb:Delta-coat protein(gene name synonym) psi-mi:sur1_yeast(display_long)|uniprotkb:SUR1(gene name)|psi-mi:SUR1(display_short)|uniprotkb:YPL057C(locus name)|uniprotkb:BCL21(gene name synonym)|uniprotkb:CSG1(gene name synonym)|uniprotkb:LPE15(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323986|imex:IM-14275-916 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001947|refseq:NP_116709.3|dip:DIP-5255N|mint:P43621|ensemblfungi:YFR051C(gene)|ensemblfungi:YFR051C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|rcsb pdb:5FJW|rcsb pdb:5FJX|rcsb pdb:5FJZ|rcsb pdb:5FK0|reactome:R-SCE-6807878|reactome:R-SCE-6811434 ensemblfungi:YPL057C(gene)|ensemblfungi:YPL057C_mRNA(transcript)|go:"GO:0000030"(mannosyltransferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0006675"(mannosyl-inositol phosphorylceramide metabolic process)|go:"GO:0006688"(glycosphingolipid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0051999"(mannosyl-inositol phosphorylceramide biosynthetic process)|interpro:IPR007577(Glycosyltransferase sugar-binding region containing DXD motif)|interpro:IPR029044|refseq:NP_015268.1|sgd:S000005978|dip:DIP-4557N|mint:P33300 psi-mi:"MI:0469"(intact) crc64:AA730F046655EE5A crc64:5A9AAB5F9A4069E3 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:auvjuT8ffm1R4P3mRKEIWAsynW0559292 rogid:EJcMJxgSg3KmU6/RI3fAbMFCu9M559292 intact-crc:7844BE24DB08F07D|rigid:CQADoG7LPQhd+qWUekdgTJ3IA0M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33302 uniprotkb:P32465 intact:EBI-13038|uniprotkb:D6W2L0|ensemblfungi:YOR153W intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 psi-mi:pdr5_yeast(display_long)|uniprotkb:PDR5(gene name)|psi-mi:PDR5(display_short)|uniprotkb:LEM1(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 5(gene name synonym)|uniprotkb:Suppressor of toxicity of sporidesmin(gene name synonym)|uniprotkb:YOR153W(locus name) psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6323997|imex:IM-14275-917 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005679|refseq:NP_014796.3|mint:P33302|dip:DIP-6776N|ensemblfungi:YOR153W(gene)|ensemblfungi:YOR153W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR029481|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926 ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sd6SJWf6B0rDZnLVaPHyvr4lhew559292 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 intact-crc:8F5FFEFC0DAC97AF|rigid:1YroaIquMwzROGoMXvuZpof+9rw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33302 uniprotkb:P33302 intact:EBI-13038|uniprotkb:D6W2L0|ensemblfungi:YOR153W intact:EBI-13038|uniprotkb:D6W2L0|ensemblfungi:YOR153W psi-mi:pdr5_yeast(display_long)|uniprotkb:PDR5(gene name)|psi-mi:PDR5(display_short)|uniprotkb:LEM1(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 5(gene name synonym)|uniprotkb:Suppressor of toxicity of sporidesmin(gene name synonym)|uniprotkb:YOR153W(locus name) psi-mi:pdr5_yeast(display_long)|uniprotkb:PDR5(gene name)|psi-mi:PDR5(display_short)|uniprotkb:LEM1(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 5(gene name synonym)|uniprotkb:Suppressor of toxicity of sporidesmin(gene name synonym)|uniprotkb:YOR153W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324008|imex:IM-14275-918 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005679|refseq:NP_014796.3|mint:P33302|dip:DIP-6776N|ensemblfungi:YOR153W(gene)|ensemblfungi:YOR153W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR029481|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926 sgd:S000005679|refseq:NP_014796.3|mint:P33302|dip:DIP-6776N|ensemblfungi:YOR153W(gene)|ensemblfungi:YOR153W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR029481|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sd6SJWf6B0rDZnLVaPHyvr4lhew559292 rogid:Sd6SJWf6B0rDZnLVaPHyvr4lhew559292 intact-crc:2FAACCBA3A3D496F|rigid:/DKZcT9cYe8Q0eQgKjY6fU9ZGb4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33302 uniprotkb:P38695 intact:EBI-13038|uniprotkb:D6W2L0|ensemblfungi:YOR153W intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 psi-mi:pdr5_yeast(display_long)|uniprotkb:PDR5(gene name)|psi-mi:PDR5(display_short)|uniprotkb:LEM1(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 5(gene name synonym)|uniprotkb:Suppressor of toxicity of sporidesmin(gene name synonym)|uniprotkb:YOR153W(locus name) psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324019|imex:IM-14275-919 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005679|refseq:NP_014796.3|mint:P33302|dip:DIP-6776N|ensemblfungi:YOR153W(gene)|ensemblfungi:YOR153W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR029481|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926 ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N psi-mi:"MI:0469"(intact) - crc64:6906721BAC1A5F87 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sd6SJWf6B0rDZnLVaPHyvr4lhew559292 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 intact-crc:C508D45AF0006D09|rigid:7iRriliej174lyXZ5YhMjH4NwI4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33302 uniprotkb:P40474 intact:EBI-13038|uniprotkb:D6W2L0|ensemblfungi:YOR153W intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W psi-mi:pdr5_yeast(display_long)|uniprotkb:PDR5(gene name)|psi-mi:PDR5(display_short)|uniprotkb:LEM1(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 5(gene name synonym)|uniprotkb:Suppressor of toxicity of sporidesmin(gene name synonym)|uniprotkb:YOR153W(locus name) psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324030|imex:IM-14275-920 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005679|refseq:NP_014796.3|mint:P33302|dip:DIP-6776N|ensemblfungi:YOR153W(gene)|ensemblfungi:YOR153W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR029481|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926 refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sd6SJWf6B0rDZnLVaPHyvr4lhew559292 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 intact-crc:A15A3AF6703DE35F|rigid:nMJg3yuznuwLZI3xbIvNH5M2QUU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33302 uniprotkb:P50276 intact:EBI-13038|uniprotkb:D6W2L0|ensemblfungi:YOR153W intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:pdr5_yeast(display_long)|uniprotkb:PDR5(gene name)|psi-mi:PDR5(display_short)|uniprotkb:LEM1(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 5(gene name synonym)|uniprotkb:Suppressor of toxicity of sporidesmin(gene name synonym)|uniprotkb:YOR153W(locus name) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324041|imex:IM-14275-921 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005679|refseq:NP_014796.3|mint:P33302|dip:DIP-6776N|ensemblfungi:YOR153W(gene)|ensemblfungi:YOR153W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR029481|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926 ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sd6SJWf6B0rDZnLVaPHyvr4lhew559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:AC2DD3CD5EB888E9|rigid:ik3Xp3i0aVusXX1ygg5cgPFJdC8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33302 uniprotkb:P53283 intact:EBI-13038|uniprotkb:D6W2L0|ensemblfungi:YOR153W intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:pdr5_yeast(display_long)|uniprotkb:PDR5(gene name)|psi-mi:PDR5(display_short)|uniprotkb:LEM1(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 5(gene name synonym)|uniprotkb:Suppressor of toxicity of sporidesmin(gene name synonym)|uniprotkb:YOR153W(locus name) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324052|imex:IM-14275-922 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005679|refseq:NP_014796.3|mint:P33302|dip:DIP-6776N|ensemblfungi:YOR153W(gene)|ensemblfungi:YOR153W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR029481|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926 refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sd6SJWf6B0rDZnLVaPHyvr4lhew559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 intact-crc:81DED39BE456AAE9|rigid:zIdWycDKvwiiuk8OYBv7Mdsxnn0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33302 uniprotkb:P53388 intact:EBI-13038|uniprotkb:D6W2L0|ensemblfungi:YOR153W intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W psi-mi:pdr5_yeast(display_long)|uniprotkb:PDR5(gene name)|psi-mi:PDR5(display_short)|uniprotkb:LEM1(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 5(gene name synonym)|uniprotkb:Suppressor of toxicity of sporidesmin(gene name synonym)|uniprotkb:YOR153W(locus name) psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324063|imex:IM-14275-923 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005679|refseq:NP_014796.3|mint:P33302|dip:DIP-6776N|ensemblfungi:YOR153W(gene)|ensemblfungi:YOR153W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR029481|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926 refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) psi-mi:"MI:0469"(intact) - crc64:488A382656039D0B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sd6SJWf6B0rDZnLVaPHyvr4lhew559292 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 intact-crc:038CC879AECE9F47|rigid:Q7IwHHl7e176B3YpBFl+TuFsFE4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33302 uniprotkb:Q02785 intact:EBI-13038|uniprotkb:D6W2L0|ensemblfungi:YOR153W intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:pdr5_yeast(display_long)|uniprotkb:PDR5(gene name)|psi-mi:PDR5(display_short)|uniprotkb:LEM1(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 5(gene name synonym)|uniprotkb:Suppressor of toxicity of sporidesmin(gene name synonym)|uniprotkb:YOR153W(locus name) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324074|imex:IM-14275-924 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005679|refseq:NP_014796.3|mint:P33302|dip:DIP-6776N|ensemblfungi:YOR153W(gene)|ensemblfungi:YOR153W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR029481|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926 refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sd6SJWf6B0rDZnLVaPHyvr4lhew559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:C82334E6D6D865A6|rigid:WX8TZ92KdUGq6lhs7BVCOhPsMJE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33302 uniprotkb:Q07824 intact:EBI-13038|uniprotkb:D6W2L0|ensemblfungi:YOR153W intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W psi-mi:pdr5_yeast(display_long)|uniprotkb:PDR5(gene name)|psi-mi:PDR5(display_short)|uniprotkb:LEM1(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 5(gene name synonym)|uniprotkb:Suppressor of toxicity of sporidesmin(gene name synonym)|uniprotkb:YOR153W(locus name) psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324085|imex:IM-14275-925 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005679|refseq:NP_014796.3|mint:P33302|dip:DIP-6776N|ensemblfungi:YOR153W(gene)|ensemblfungi:YOR153W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR029481|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926 refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sd6SJWf6B0rDZnLVaPHyvr4lhew559292 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 intact-crc:38A6F249BBAC1961|rigid:YhICvQEJMfh5Uir1OjGgNZOprN8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48362 uniprotkb:P33313 intact:EBI-8304|uniprotkb:D6VUX0|ensemblfungi:YGR187C intact:EBI-4806|uniprotkb:Q02125|uniprotkb:D6VQF0|ensemblfungi:YBR155W psi-mi:hgh1_yeast(display_long)|uniprotkb:HGH1(gene name)|psi-mi:HGH1(display_short)|uniprotkb:HMG1/2 protein homolog(gene name synonym)|uniprotkb:G7538(orf name)|uniprotkb:YGR187C(locus name) psi-mi:cns1_yeast(display_long)|uniprotkb:CNS1(gene name)|psi-mi:CNS1(display_short)|uniprotkb:YBR155W(locus name)|uniprotkb:YBR1205(orf name)|uniprotkb:Cyclophilin seven suppressor 1(gene name synonym)|uniprotkb:STI1 stress-inducible protein homolog(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324096|imex:IM-14275-926 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003419|refseq:NP_011703.3|mint:P48362|dip:DIP-4721N|ensemblfungi:YGR187C(gene)|ensemblfungi:YGR187C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061770"(translation elongation factor binding)|interpro:IPR007205(Protein of unknown function DUF383)|interpro:IPR007206(Protein of unknown function DUF384)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039717|rcsb pdb:6HB1|rcsb pdb:6HB2|rcsb pdb:6HB3 refseq:NP_009713.1|sgd:S000000359|dip:DIP-1271N|mint:P33313|ensemblfungi:YBR155W(gene)|ensemblfungi:YBR155W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0043022"(ribosome binding)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044059|rcsb pdb:6HFM|rcsb pdb:6HFT psi-mi:"MI:0469"(intact) crc64:24D4EFAEBD5D7A48 crc64:742F8254DFDB02A6 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YQkKPiBqhycG0Z+2lxERBLVdy1w559292 rogid:3vEtWsrh/ufn1qHwPkr6Iz+6qCs559292 intact-crc:BEBF1F2FCA4EFBC3|rigid:+mwSwxSzRyy3hW/GYMjVky/XCsc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23542 uniprotkb:P33327 intact:EBI-2002|uniprotkb:D6VY29|ensemblfungi:YLR027C intact:EBI-5815|ensemblfungi:YDL215C|uniprotkb:D6VRD9 psi-mi:aatc_yeast(display_long)|uniprotkb:AAT2(gene name)|psi-mi:AAT2(display_short)|uniprotkb:YLR027C(locus name)|uniprotkb:ASP5(gene name synonym)|uniprotkb:L1746(orf name)|uniprotkb:Transaminase A(gene name synonym) psi-mi:dhe2_yeast(display_long)|uniprotkb:YDL215C(locus name)|uniprotkb:GDH2(gene name)|psi-mi:GDH2(display_short)|uniprotkb:D0892(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324107|imex:IM-14275-927 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013127.2|sgd:S000004017|dip:DIP-2897N|mint:P23542|go:"GO:0019266"(asparagine biosynthetic process from oxaloacetate)|go:"GO:0030170"(pyridoxal phosphate binding)|interpro:IPR000796(Aspartate/other aminotransferase)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:1YAA|reactome:R-SCE-70263|reactome:R-SCE-8963693|ensemblfungi:YLR027C(gene)|ensemblfungi:YLR027C_mRNA(transcript)|go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0006532"(aspartate biosynthetic process)|go:"GO:0006536"(glutamate metabolic process) ensemblfungi:YDL215C(gene)|ensemblfungi:YDL215C_mRNA(transcript)|go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0019551"(glutamate catabolic process to 2-oxoglutarate)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR016210(Glutamate dehydrogenase, NAD-dependent)|interpro:IPR033524|interpro:IPR036291|refseq:NP_010066.1|sgd:S000002374|dip:DIP-1689N|mint:P33327 psi-mi:"MI:0469"(intact) crc64:D25F40F6C6DD2B33 crc64:DF8358D831E4545F figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:eNypS723YWwMMuWVVoTnidvQuaA559292 rogid:bjvKAO4gyrNUq2Wwq3Y+FvEv7RM559292 intact-crc:F9D3DE65A1F0DB2A|rigid:hGx2LYcfsk6EbYKusqooXuOnKOI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33327 uniprotkb:P33327 intact:EBI-5815|ensemblfungi:YDL215C|uniprotkb:D6VRD9 intact:EBI-5815|ensemblfungi:YDL215C|uniprotkb:D6VRD9 psi-mi:dhe2_yeast(display_long)|uniprotkb:YDL215C(locus name)|uniprotkb:GDH2(gene name)|psi-mi:GDH2(display_short)|uniprotkb:D0892(orf name) psi-mi:dhe2_yeast(display_long)|uniprotkb:YDL215C(locus name)|uniprotkb:GDH2(gene name)|psi-mi:GDH2(display_short)|uniprotkb:D0892(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324118|imex:IM-14275-928 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDL215C(gene)|ensemblfungi:YDL215C_mRNA(transcript)|go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0019551"(glutamate catabolic process to 2-oxoglutarate)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR016210(Glutamate dehydrogenase, NAD-dependent)|interpro:IPR033524|interpro:IPR036291|refseq:NP_010066.1|sgd:S000002374|dip:DIP-1689N|mint:P33327 ensemblfungi:YDL215C(gene)|ensemblfungi:YDL215C_mRNA(transcript)|go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0019551"(glutamate catabolic process to 2-oxoglutarate)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR016210(Glutamate dehydrogenase, NAD-dependent)|interpro:IPR033524|interpro:IPR036291|refseq:NP_010066.1|sgd:S000002374|dip:DIP-1689N|mint:P33327 psi-mi:"MI:0469"(intact) crc64:DF8358D831E4545F crc64:DF8358D831E4545F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:bjvKAO4gyrNUq2Wwq3Y+FvEv7RM559292 rogid:bjvKAO4gyrNUq2Wwq3Y+FvEv7RM559292 intact-crc:278A990485B68CAE|rigid:HHQXn4LqZvOSvxz43PxzhQF/rJM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22137 uniprotkb:P33328 intact:EBI-4766|uniprotkb:D6VTU9|ensemblfungi:YGL206C intact:EBI-17512|uniprotkb:D6W324|ensemblfungi:YOR327C psi-mi:clh_yeast(display_long)|uniprotkb:CHC1(gene name)|psi-mi:CHC1(display_short)|uniprotkb:YGL206C(locus name) psi-mi:snc2_yeast(display_long)|uniprotkb:SNC2(gene name)|psi-mi:SNC2(display_short)|uniprotkb:YOR327C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324129|imex:IM-14275-929 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011309.1|sgd:S000003174|dip:DIP-2279N|mint:P22137|ensemblfungi:YGL206C(gene)|ensemblfungi:YGL206C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0071439"(clathrin complex)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-432720|reactome:R-SCE-437239|reactome:R-SCE-8856828|reactome:R-SCE-8866427|reactome:R-SCE-8964038 refseq:NP_014972.3|sgd:S000005854|ensemblfungi:YOR327C(gene)|ensemblfungi:YOR327C_mRNA(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|dip:DIP-4667N|mint:P33328 psi-mi:"MI:0469"(intact) crc64:622F3083DF2FE315 crc64:815F027FAD8A599B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SAN6H3nVFozXZyTiRLaljMcIKIA559292 rogid:q9N0ivbJw8/WCA1l24ymObTMu0s559292 intact-crc:0550D8712800D6FB|rigid:rGK4tZznhb1oFXQq1frY2cVfxiE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32610 uniprotkb:P33328 intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W intact:EBI-17512|uniprotkb:D6W324|ensemblfungi:YOR327C psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym) psi-mi:snc2_yeast(display_long)|uniprotkb:SNC2(gene name)|psi-mi:SNC2(display_short)|uniprotkb:YOR327C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324140|imex:IM-14275-930 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610 refseq:NP_014972.3|sgd:S000005854|ensemblfungi:YOR327C(gene)|ensemblfungi:YOR327C_mRNA(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|dip:DIP-4667N|mint:P33328 psi-mi:"MI:0469"(intact) crc64:FDE93E1FAF0AEC5B crc64:815F027FAD8A599B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292 rogid:q9N0ivbJw8/WCA1l24ymObTMu0s559292 intact-crc:9BA301817209DE6D|rigid:pENkS+lCWnVQKY8mvnUvJyf8onI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37012 uniprotkb:P33328 intact:EBI-13296|uniprotkb:D6VZS7|ensemblfungi:YMR105C intact:EBI-17512|uniprotkb:D6W324|ensemblfungi:YOR327C psi-mi:pgm2_yeast(display_long)|uniprotkb:PGM2(gene name)|psi-mi:PGM2(display_short)|uniprotkb:GAL5(gene name synonym)|uniprotkb:YMR105C(locus name)|uniprotkb:YM9718.04C(orf name)|uniprotkb:Glucose phosphomutase 2(gene name synonym)|uniprotkb:"D-glucose-1,6-diphosphate:D-glucose-1-phosphate phosphotransferase"(gene name synonym)|uniprotkb:GA-5(gene name synonym) psi-mi:snc2_yeast(display_long)|uniprotkb:SNC2(gene name)|psi-mi:SNC2(display_short)|uniprotkb:YOR327C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324151|imex:IM-14275-931 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013823.1|sgd:S000004711|mint:P37012|dip:DIP-6499N|ensemblfungi:YMR105C(gene)|ensemblfungi:YMR105C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004614"(phosphoglucomutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019255"(glucose 1-phosphate metabolic process)|go:"GO:0019388"(galactose catabolic process)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR036900 refseq:NP_014972.3|sgd:S000005854|ensemblfungi:YOR327C(gene)|ensemblfungi:YOR327C_mRNA(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|dip:DIP-4667N|mint:P33328 psi-mi:"MI:0469"(intact) crc64:45B78AFF8197645E crc64:815F027FAD8A599B figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miT4vpKTbsa/OfXIppW6h1+TbPs559292 rogid:q9N0ivbJw8/WCA1l24ymObTMu0s559292 intact-crc:A53AB4387CAB4A1E|rigid:zEpVipgVQVwg/pmfCpB0yUnsWpM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38009 uniprotkb:P33328 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 intact:EBI-17512|uniprotkb:D6W324|ensemblfungi:YOR327C psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:snc2_yeast(display_long)|uniprotkb:SNC2(gene name)|psi-mi:SNC2(display_short)|uniprotkb:YOR327C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324162|imex:IM-14275-932 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N refseq:NP_014972.3|sgd:S000005854|ensemblfungi:YOR327C(gene)|ensemblfungi:YOR327C_mRNA(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|dip:DIP-4667N|mint:P33328 psi-mi:"MI:0469"(intact) crc64:8ABA71761B512242 crc64:815F027FAD8A599B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 rogid:q9N0ivbJw8/WCA1l24ymObTMu0s559292 intact-crc:7AA3111BFDE86DCC|rigid:p6daYv/KDsYmzhxmfaT0jAaR4zM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33328 uniprotkb:P38328 intact:EBI-17512|uniprotkb:D6W324|ensemblfungi:YOR327C intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C psi-mi:snc2_yeast(display_long)|uniprotkb:SNC2(gene name)|psi-mi:SNC2(display_short)|uniprotkb:YOR327C(locus name) psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324173|imex:IM-14275-933 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014972.3|sgd:S000005854|ensemblfungi:YOR327C(gene)|ensemblfungi:YOR327C_mRNA(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|dip:DIP-4667N|mint:P33328 sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:815F027FAD8A599B crc64:D75C6BB8EC35EEDF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:q9N0ivbJw8/WCA1l24ymObTMu0s559292 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 intact-crc:865688E0893DB538|rigid:ENpSINhZYJ7AM/BOcnX77vfvqno false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33328 uniprotkb:P41811 intact:EBI-17512|uniprotkb:D6W324|ensemblfungi:YOR327C intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:snc2_yeast(display_long)|uniprotkb:SNC2(gene name)|psi-mi:SNC2(display_short)|uniprotkb:YOR327C(locus name) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324184|imex:IM-14275-934 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014972.3|sgd:S000005854|ensemblfungi:YOR327C(gene)|ensemblfungi:YOR327C_mRNA(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|dip:DIP-4667N|mint:P33328 refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:815F027FAD8A599B crc64:6A5E50BBEB02CB58 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:q9N0ivbJw8/WCA1l24ymObTMu0s559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:9B75EBFD4223626F|rigid:DEvEqIWgsktlwDR0AODW78Exl90 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33328 uniprotkb:P47039 intact:EBI-17512|uniprotkb:D6W324|ensemblfungi:YOR327C intact:EBI-25893|uniprotkb:D6VWC2|ensemblfungi:YJL060W psi-mi:snc2_yeast(display_long)|uniprotkb:SNC2(gene name)|psi-mi:SNC2(display_short)|uniprotkb:YOR327C(locus name) psi-mi:bna3_yeast(display_long)|uniprotkb:YJL060W(locus name)|uniprotkb:J1138(orf name)|uniprotkb:Biosynthesis of nicotinic acid protein 3(gene name synonym)|uniprotkb:BNA3(gene name)|psi-mi:BNA3(display_short)|uniprotkb:Kynurenine aminotransferase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324195|imex:IM-14275-935 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014972.3|sgd:S000005854|ensemblfungi:YOR327C(gene)|ensemblfungi:YOR327C_mRNA(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|dip:DIP-4667N|mint:P33328 sgd:S000003596|refseq:NP_012475.3|mint:P47039|dip:DIP-6723N|ensemblfungi:YJL060W(gene)|ensemblfungi:YJL060W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0016212"(kynurenine-oxoglutarate transaminase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034276"(kynurenic acid biosynthetic process)|go:"GO:0047536"(2-aminoadipate transaminase activity)|go:"GO:0097053"(L-kynurenine catabolic process)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:3B46|reactome:R-SCE-71240|reactome:R-SCE-8964208|reactome:R-SCE-8964539 psi-mi:"MI:0469"(intact) crc64:815F027FAD8A599B - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:q9N0ivbJw8/WCA1l24ymObTMu0s559292 rogid:Fli6ip0tteNbMkQG9h7/IBow3ms559292 intact-crc:2F0659B3EEC1830A|rigid:4/NHjdik6TNlrPotRYvCRGxXc90 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54783 uniprotkb:P33328 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 intact:EBI-17512|uniprotkb:D6W324|ensemblfungi:YOR327C psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:snc2_yeast(display_long)|uniprotkb:SNC2(gene name)|psi-mi:SNC2(display_short)|uniprotkb:YOR327C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324206|imex:IM-14275-936 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 refseq:NP_014972.3|sgd:S000005854|ensemblfungi:YOR327C(gene)|ensemblfungi:YOR327C_mRNA(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|dip:DIP-4667N|mint:P33328 psi-mi:"MI:0469"(intact) - crc64:815F027FAD8A599B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 rogid:q9N0ivbJw8/WCA1l24ymObTMu0s559292 intact-crc:D9344474749CEB91|rigid:2iwst1NTPsttx8CKlWXTAEbzNF8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36024 uniprotkb:P33329 intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C intact:EBI-13815|ensemblfungi:YDR436W|uniprotkb:D6VT63 psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym) psi-mi:ppz2_yeast(display_long)|uniprotkb:PPZ2(gene name)|psi-mi:PPZ2(display_short)|uniprotkb:D9461.22(orf name)|uniprotkb:YDR436W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324217|imex:IM-14275-937 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024 ensemblfungi:YDR436W(gene)|ensemblfungi:YDR436W_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0046872"(metal ion binding)|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|go:"GO:0106306"|refseq:NP_010724.1|sgd:S000002844|mint:P33329|dip:DIP-6355N psi-mi:"MI:0469"(intact) - crc64:3095F37046489AFB figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292 rogid:WpYxSWimbMNz9ZdZHpezPp/B2Sc559292 intact-crc:89F070BACF3E2D61|rigid:G3dy8h3s9baJSId72feKCA3G+CM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33329 uniprotkb:P36076 intact:EBI-13815|ensemblfungi:YDR436W|uniprotkb:D6VT63 intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W psi-mi:ppz2_yeast(display_long)|uniprotkb:PPZ2(gene name)|psi-mi:PPZ2(display_short)|uniprotkb:D9461.22(orf name)|uniprotkb:YDR436W(locus name) psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324228|imex:IM-14275-938 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR436W(gene)|ensemblfungi:YDR436W_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0046872"(metal ion binding)|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|go:"GO:0106306"|refseq:NP_010724.1|sgd:S000002844|mint:P33329|dip:DIP-6355N refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783 psi-mi:"MI:0469"(intact) crc64:3095F37046489AFB - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WpYxSWimbMNz9ZdZHpezPp/B2Sc559292 rogid:Li7vZOassm4PC5fW111/j5ivgEc559292 intact-crc:02A33BD13A64B4EF|rigid:hSKf1FEveSwJ/k0en0pHN/aMCe4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P33333 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-13494|uniprotkb:E9P8Y5|uniprotkb:D6VRU4|ensemblfungi:YDL052C psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:plsc_yeast(display_long)|uniprotkb:SLC1(gene name)|psi-mi:SLC1(display_short)|uniprotkb:Lysophosphatidic acid acyltransferase(gene name synonym)|uniprotkb:Sphingolipid compensation protein 1(gene name synonym)|uniprotkb:YDL052C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324239|imex:IM-14275-939 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_010231.1|sgd:S000002210|reactome:R-SCE-6798695|reactome:R-SCE-163765|ensemblfungi:YDL052C(gene)|ensemblfungi:YDL052C_mRNA(transcript)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0106262"(1-acylglycerophosphoethanolamine O-acyltransferase activity)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR004552(1-acyl-sn-glycerol-3-phosphate acyltransferase)|reactome:R-SCE-1483166|mint:P33333|dip:DIP-5136N psi-mi:"MI:0469"(intact) - crc64:36ECBBC2659655EB figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:ejhdgzoC8mw+T73h5cM4ReS9vPU559292 intact-crc:C779DFDF22745212|rigid:3rlfgB6zitEmtjOQfUi+beJbPmg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33333 uniprotkb:P14359 intact:EBI-13494|uniprotkb:E9P8Y5|uniprotkb:D6VRU4|ensemblfungi:YDL052C intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:plsc_yeast(display_long)|uniprotkb:SLC1(gene name)|psi-mi:SLC1(display_short)|uniprotkb:Lysophosphatidic acid acyltransferase(gene name synonym)|uniprotkb:Sphingolipid compensation protein 1(gene name synonym)|uniprotkb:YDL052C(locus name) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324250|imex:IM-14275-940 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010231.1|sgd:S000002210|reactome:R-SCE-6798695|reactome:R-SCE-163765|ensemblfungi:YDL052C(gene)|ensemblfungi:YDL052C_mRNA(transcript)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0106262"(1-acylglycerophosphoethanolamine O-acyltransferase activity)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR004552(1-acyl-sn-glycerol-3-phosphate acyltransferase)|reactome:R-SCE-1483166|mint:P33333|dip:DIP-5136N refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) crc64:36ECBBC2659655EB crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ejhdgzoC8mw+T73h5cM4ReS9vPU559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:D554876893C4D543|rigid:elZZ8gNagWZb4X4xGYho/oL60WY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28321 uniprotkb:P33333 intact:EBI-26790|uniprotkb:D6VXJ4|ensemblfungi:YKL094W intact:EBI-13494|uniprotkb:E9P8Y5|uniprotkb:D6VRU4|ensemblfungi:YDL052C psi-mi:mgll_yeast(display_long)|uniprotkb:YJU3(gene name)|psi-mi:YJU3(display_short)|uniprotkb:Monoacylglycerol hydrolase(gene name synonym)|uniprotkb:Monoacylglycerol lipase(gene name synonym)|uniprotkb:Serine hydrolase YJU3(gene name synonym)|uniprotkb:YKL441(orf name)|uniprotkb:YKL094W(locus name)|uniprotkb:Fatty acid ethyl ester hydrolase(gene name synonym) psi-mi:plsc_yeast(display_long)|uniprotkb:SLC1(gene name)|psi-mi:SLC1(display_short)|uniprotkb:Lysophosphatidic acid acyltransferase(gene name synonym)|uniprotkb:Sphingolipid compensation protein 1(gene name synonym)|uniprotkb:YDL052C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324261|imex:IM-14275-941 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022742|refseq:NP_012829.1|sgd:S000001577|mint:P28321|interpro:IPR029058|ensemblfungi:YKL094W(gene)|ensemblfungi:YKL094W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0071944"(cell periphery)|rcsb pdb:4ZWN|rcsb pdb:4ZXF refseq:NP_010231.1|sgd:S000002210|reactome:R-SCE-6798695|reactome:R-SCE-163765|ensemblfungi:YDL052C(gene)|ensemblfungi:YDL052C_mRNA(transcript)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0106262"(1-acylglycerophosphoethanolamine O-acyltransferase activity)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR004552(1-acyl-sn-glycerol-3-phosphate acyltransferase)|reactome:R-SCE-1483166|mint:P33333|dip:DIP-5136N psi-mi:"MI:0469"(intact) - crc64:36ECBBC2659655EB figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IHpY1aez3MG+bn7bThCBdvE6KMw559292 rogid:ejhdgzoC8mw+T73h5cM4ReS9vPU559292 intact-crc:E9B8F020C43A4C89|rigid:P6Dyo6o+LNurjlPyq4IZPRaJvq8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35196 uniprotkb:P33333 intact:EBI-14943|uniprotkb:D6VQ03|ensemblfungi:YBR002C intact:EBI-13494|uniprotkb:E9P8Y5|uniprotkb:D6VRU4|ensemblfungi:YDL052C psi-mi:rer2_yeast(display_long)|uniprotkb:"Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific)"(gene name synonym)|uniprotkb:YBR0107(orf name)|uniprotkb:RER2(gene name)|psi-mi:RER2(display_short)|uniprotkb:YBR002C(locus name) psi-mi:plsc_yeast(display_long)|uniprotkb:SLC1(gene name)|psi-mi:SLC1(display_short)|uniprotkb:Lysophosphatidic acid acyltransferase(gene name synonym)|uniprotkb:Sphingolipid compensation protein 1(gene name synonym)|uniprotkb:YDL052C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324272|imex:IM-14275-942 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036424|refseq:NP_009556.1|sgd:S000000206|interpro:IPR001441(Di-trans-poly-cis-decaprenylcistransferase)|interpro:IPR018520|ensemblfungi:YBR002C(gene)|ensemblfungi:YBR002C_mRNA(transcript)|go:"GO:0002094"(polyprenyltransferase activity)|go:"GO:0004659"(prenyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016094"(polyprenol biosynthetic process)|go:"GO:0019408"(dolichol biosynthetic process)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0045547"(dehydrodolichyl diphosphate synthase activity)|go:"GO:1904423"(dehydrodolichyl diphosphate synthase complex)|reactome:R-SCE-446199|mint:P35196 refseq:NP_010231.1|sgd:S000002210|reactome:R-SCE-6798695|reactome:R-SCE-163765|ensemblfungi:YDL052C(gene)|ensemblfungi:YDL052C_mRNA(transcript)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0106262"(1-acylglycerophosphoethanolamine O-acyltransferase activity)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR004552(1-acyl-sn-glycerol-3-phosphate acyltransferase)|reactome:R-SCE-1483166|mint:P33333|dip:DIP-5136N psi-mi:"MI:0469"(intact) - crc64:36ECBBC2659655EB figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:gVl9E/6GKqKsUp/5VLdT5XGbjUM559292 rogid:ejhdgzoC8mw+T73h5cM4ReS9vPU559292 intact-crc:756EC9C78A2EEB4E|rigid:WgZmzKfL2z0Mt0VCIBbbRzjNjvw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35844 uniprotkb:P33333 intact:EBI-9648|ensemblfungi:YPL145C|uniprotkb:D6W3M4|uniprotkb:E9P8U8 intact:EBI-13494|uniprotkb:E9P8Y5|uniprotkb:D6VRU4|ensemblfungi:YDL052C psi-mi:kes1_yeast(display_long)|uniprotkb:KES1(gene name)|psi-mi:KES1(display_short)|uniprotkb:OSH4(gene name synonym)|uniprotkb:Protein KES1(gene name synonym)|uniprotkb:LPI3C(orf name)|uniprotkb:P2614(orf name)|uniprotkb:YPL145C(locus name) psi-mi:plsc_yeast(display_long)|uniprotkb:SLC1(gene name)|psi-mi:SLC1(display_short)|uniprotkb:Lysophosphatidic acid acyltransferase(gene name synonym)|uniprotkb:Sphingolipid compensation protein 1(gene name synonym)|uniprotkb:YDL052C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324283|imex:IM-14275-943 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL145C(gene)|ensemblfungi:YPL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035621"(ER to Golgi ceramide transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|rcsb pdb:1ZHT|rcsb pdb:1ZHW|rcsb pdb:1ZHX|rcsb pdb:1ZHY|rcsb pdb:1ZHZ|rcsb pdb:1ZI7|rcsb pdb:3SPW|rcsb pdb:4F4B|rcsb pdb:4FES|rcsb pdb:4JCH|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_015180.1|sgd:S000006066|dip:DIP-2867N|mint:P35844 refseq:NP_010231.1|sgd:S000002210|reactome:R-SCE-6798695|reactome:R-SCE-163765|ensemblfungi:YDL052C(gene)|ensemblfungi:YDL052C_mRNA(transcript)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0106262"(1-acylglycerophosphoethanolamine O-acyltransferase activity)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR004552(1-acyl-sn-glycerol-3-phosphate acyltransferase)|reactome:R-SCE-1483166|mint:P33333|dip:DIP-5136N psi-mi:"MI:0469"(intact) - crc64:36ECBBC2659655EB figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6vsHrA4RScGr2+xmii0wiuvK1OM559292 rogid:ejhdgzoC8mw+T73h5cM4ReS9vPU559292 intact-crc:F11BE8841C4CDA64|rigid:eb48msrhOGzKPJaN1LB8FUKX68Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38225 uniprotkb:P33333 intact:EBI-6819|uniprotkb:O60021|uniprotkb:Q86ZS3|uniprotkb:D6VQ41|ensemblfungi:YBR041W intact:EBI-13494|uniprotkb:E9P8Y5|uniprotkb:D6VRU4|ensemblfungi:YDL052C psi-mi:fat1_yeast(display_long)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:Very-long-chain acyl-CoA synthetase(gene name synonym)|uniprotkb:YBR0411(orf name)|uniprotkb:YBR041W(locus name) psi-mi:plsc_yeast(display_long)|uniprotkb:SLC1(gene name)|psi-mi:SLC1(display_short)|uniprotkb:Lysophosphatidic acid acyltransferase(gene name synonym)|uniprotkb:Sphingolipid compensation protein 1(gene name synonym)|uniprotkb:YDL052C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324294|imex:IM-14275-944 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009597.2|sgd:S000000245|mint:P38225|dip:DIP-5048N|ensemblfungi:YBR041W(gene)|ensemblfungi:YBR041W_mRNA(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0071944"(cell periphery)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR030310|interpro:IPR042099|reactome:R-SCE-159418|reactome:R-SCE-193368|reactome:R-SCE-193775|reactome:R-SCE-389599|reactome:R-SCE-6798695|reactome:R-SCE-804914|reactome:R-SCE-9033241 refseq:NP_010231.1|sgd:S000002210|reactome:R-SCE-6798695|reactome:R-SCE-163765|ensemblfungi:YDL052C(gene)|ensemblfungi:YDL052C_mRNA(transcript)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0106262"(1-acylglycerophosphoethanolamine O-acyltransferase activity)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR004552(1-acyl-sn-glycerol-3-phosphate acyltransferase)|reactome:R-SCE-1483166|mint:P33333|dip:DIP-5136N psi-mi:"MI:0469"(intact) crc64:509A5DEDDEE98823 crc64:36ECBBC2659655EB figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mGjvEcQ/ZVHp/P+89KaQ7DrjcQg559292 rogid:ejhdgzoC8mw+T73h5cM4ReS9vPU559292 intact-crc:41F3A9FE37675622|rigid:R6kaaNDZVTRO8vb0REy2QZHP+Fg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33333 uniprotkb:P38604 intact:EBI-13494|uniprotkb:E9P8Y5|uniprotkb:D6VRU4|ensemblfungi:YDL052C intact:EBI-6572|uniprotkb:Q92327|uniprotkb:D3DL21|ensemblfungi:YHR072W psi-mi:plsc_yeast(display_long)|uniprotkb:SLC1(gene name)|psi-mi:SLC1(display_short)|uniprotkb:Lysophosphatidic acid acyltransferase(gene name synonym)|uniprotkb:Sphingolipid compensation protein 1(gene name synonym)|uniprotkb:YDL052C(locus name) psi-mi:erg7_yeast(display_long)|uniprotkb:Oxidosqualene--lanosterol cyclase(gene name synonym)|uniprotkb:2,3-epoxysqualene--lanosterol cyclase(gene name synonym)|uniprotkb:YHR072W(locus name)|uniprotkb:ERG7(gene name)|psi-mi:ERG7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324305|imex:IM-14275-945 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010231.1|sgd:S000002210|reactome:R-SCE-6798695|reactome:R-SCE-163765|ensemblfungi:YDL052C(gene)|ensemblfungi:YDL052C_mRNA(transcript)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0106262"(1-acylglycerophosphoethanolamine O-acyltransferase activity)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR004552(1-acyl-sn-glycerol-3-phosphate acyltransferase)|reactome:R-SCE-1483166|mint:P33333|dip:DIP-5136N refseq:NP_011939.2|sgd:S000001114|mint:P38604|dip:DIP-8319N|ensemblfungi:YHR072W(gene)|ensemblfungi:YHR072W_mRNA(transcript)|go:"GO:0000250"(lanosterol synthase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016104"(triterpenoid biosynthetic process)|go:"GO:0042300"(beta-amyrin synthase activity)|interpro:IPR002365(Terpene synthase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR018333|interpro:IPR032696|interpro:IPR032697|reactome:R-SCE-191273 psi-mi:"MI:0469"(intact) crc64:36ECBBC2659655EB - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ejhdgzoC8mw+T73h5cM4ReS9vPU559292 rogid:zqDPA3GvKWkMTmH97TcdF8HOHBU559292 intact-crc:71B0AE2A7240771B|rigid:y9+JpRXJXkr1yu84+aRXHHm9sUw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33333 uniprotkb:P40471 intact:EBI-13494|uniprotkb:E9P8Y5|uniprotkb:D6VRU4|ensemblfungi:YDL052C intact:EBI-25213|uniprotkb:D6VVG3|ensemblfungi:YIL124W psi-mi:plsc_yeast(display_long)|uniprotkb:SLC1(gene name)|psi-mi:SLC1(display_short)|uniprotkb:Lysophosphatidic acid acyltransferase(gene name synonym)|uniprotkb:Sphingolipid compensation protein 1(gene name synonym)|uniprotkb:YDL052C(locus name) psi-mi:ayr1_yeast(display_long)|uniprotkb:AYR1(gene name)|psi-mi:AYR1(display_short)|uniprotkb:Acylglycerone-phosphate reductase(gene name synonym)|uniprotkb:1-acyl DHAP reductase(gene name synonym)|uniprotkb:Acyl/alkyl DHAP reductase(gene name synonym)|uniprotkb:GBG1(gene name synonym)|uniprotkb:Triacylglycerol lipase AYR1(gene name synonym)|uniprotkb:YIL124W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324316|imex:IM-14275-946 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010231.1|sgd:S000002210|reactome:R-SCE-6798695|reactome:R-SCE-163765|ensemblfungi:YDL052C(gene)|ensemblfungi:YDL052C_mRNA(transcript)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0106262"(1-acylglycerophosphoethanolamine O-acyltransferase activity)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR004552(1-acyl-sn-glycerol-3-phosphate acyltransferase)|reactome:R-SCE-1483166|mint:P33333|dip:DIP-5136N sgd:S000001386|refseq:NP_012142.3|mint:P40471|dip:DIP-4614N|ensemblfungi:YIL124W(gene)|ensemblfungi:YIL124W_mRNA(transcript)|go:"GO:0000140"(acylglycerone-phosphate reductase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0102566"(1-acyl dihydroxyacetone phosphate reductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291 psi-mi:"MI:0469"(intact) crc64:36ECBBC2659655EB crc64:B614C0E0B1FB0CE0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ejhdgzoC8mw+T73h5cM4ReS9vPU559292 rogid:WE4RmSXARj683MNUEsYGLis36Xo559292 intact-crc:20A5AF9C72A6D6B2|rigid:ZZXeMbN4dIcNj2dMNl72xLmCL5w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33333 uniprotkb:Q12168 intact:EBI-13494|uniprotkb:E9P8Y5|uniprotkb:D6VRU4|ensemblfungi:YDL052C intact:EBI-32973|uniprotkb:Q07268|uniprotkb:D6VYD8|ensemblfungi:YLR144C psi-mi:plsc_yeast(display_long)|uniprotkb:SLC1(gene name)|psi-mi:SLC1(display_short)|uniprotkb:Lysophosphatidic acid acyltransferase(gene name synonym)|uniprotkb:Sphingolipid compensation protein 1(gene name synonym)|uniprotkb:YDL052C(locus name) psi-mi:eng2_yeast(display_long)|uniprotkb:ACF2(gene name)|psi-mi:ACF2(display_short)|uniprotkb:YLR144C(locus name)|uniprotkb:Laminarinase-2(gene name synonym)|uniprotkb:ENG2(gene name synonym)|uniprotkb:PCA1(gene name synonym)|uniprotkb:L3180(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324327|imex:IM-14275-947 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010231.1|sgd:S000002210|reactome:R-SCE-6798695|reactome:R-SCE-163765|ensemblfungi:YDL052C(gene)|ensemblfungi:YDL052C_mRNA(transcript)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0106262"(1-acylglycerophosphoethanolamine O-acyltransferase activity)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR004552(1-acyl-sn-glycerol-3-phosphate acyltransferase)|reactome:R-SCE-1483166|mint:P33333|dip:DIP-5136N refseq:NP_013245.1|sgd:S000004134|mint:Q12168|dip:DIP-2889N|ensemblfungi:YLR144C(gene)|ensemblfungi:YLR144C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042973"(glucan endo-1,3-beta-D-glucosidase activity)|go:"GO:0052861"(glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group)|go:"GO:0052862"(glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group)|interpro:IPR005200(Glycoside hydrolase, family 81)|interpro:IPR040451|interpro:IPR040720 psi-mi:"MI:0469"(intact) crc64:36ECBBC2659655EB - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ejhdgzoC8mw+T73h5cM4ReS9vPU559292 rogid:8STCUe6Ie2CnTTBMjY8wrld5h44559292 intact-crc:5B216AC97B7FEEC4|rigid:ZDvXmJ2WdiEdH8O8S46gYu69DvE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22137 uniprotkb:P33338 intact:EBI-4766|uniprotkb:D6VTU9|ensemblfungi:YGL206C intact:EBI-17323|uniprotkb:Q02434|uniprotkb:D6W0V0|ensemblfungi:YNL243W psi-mi:clh_yeast(display_long)|uniprotkb:CHC1(gene name)|psi-mi:CHC1(display_short)|uniprotkb:YGL206C(locus name) psi-mi:sla2_yeast(display_long)|uniprotkb:SLA2(gene name)|psi-mi:SLA2(display_short)|uniprotkb:END4(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:UFG1(gene name synonym)|uniprotkb:YNL243W(locus name)|uniprotkb:N1102(orf name)|uniprotkb:Transmembrane protein MOP2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324338|imex:IM-14275-948 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011309.1|sgd:S000003174|dip:DIP-2279N|mint:P22137|ensemblfungi:YGL206C(gene)|ensemblfungi:YGL206C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0071439"(clathrin complex)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-432720|reactome:R-SCE-437239|reactome:R-SCE-8856828|reactome:R-SCE-8866427|reactome:R-SCE-8964038 refseq:NP_014156.2|sgd:S000005187|ensemblfungi:YNL243W(gene)|ensemblfungi:YNL243W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002558(I/LWEQ)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR030224|interpro:IPR035964|rcsb pdb:5AHV|rcsb pdb:7B2L|reactome:R-SCE-8856828|dip:DIP-973N|mint:P33338 psi-mi:"MI:0469"(intact) crc64:622F3083DF2FE315 crc64:E592E09D8040C0E9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SAN6H3nVFozXZyTiRLaljMcIKIA559292 rogid:HdBIyI4al1me0fjpCDcLIkwHEhI559292 intact-crc:740F617A0E2522A5|rigid:wLoHRcbHdjbVnIbJir/hgtDiWLo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32790 uniprotkb:P33338 intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C intact:EBI-17323|uniprotkb:Q02434|uniprotkb:D6W0V0|ensemblfungi:YNL243W psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short) psi-mi:sla2_yeast(display_long)|uniprotkb:SLA2(gene name)|psi-mi:SLA2(display_short)|uniprotkb:END4(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:UFG1(gene name synonym)|uniprotkb:YNL243W(locus name)|uniprotkb:N1102(orf name)|uniprotkb:Transmembrane protein MOP2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324349|imex:IM-14275-949 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790 refseq:NP_014156.2|sgd:S000005187|ensemblfungi:YNL243W(gene)|ensemblfungi:YNL243W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002558(I/LWEQ)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR030224|interpro:IPR035964|rcsb pdb:5AHV|rcsb pdb:7B2L|reactome:R-SCE-8856828|dip:DIP-973N|mint:P33338 psi-mi:"MI:0469"(intact) crc64:7FD85AA776407624 crc64:E592E09D8040C0E9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292 rogid:HdBIyI4al1me0fjpCDcLIkwHEhI559292 intact-crc:3F1BD98A71C35B88|rigid:FugAIbpT7fjUGF5pqmkXvu/1itI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33204 uniprotkb:P33338 intact:EBI-2757|uniprotkb:D6VXS3|ensemblfungi:YKL013C intact:EBI-17323|uniprotkb:Q02434|uniprotkb:D6W0V0|ensemblfungi:YNL243W psi-mi:arpc4_yeast(display_long)|uniprotkb:ARC19(gene name)|psi-mi:ARC19(display_short)|uniprotkb:YKL013C(locus name)|uniprotkb:YKL166(orf name)|uniprotkb:Arp2/3 complex 20 kDa(gene name synonym) psi-mi:sla2_yeast(display_long)|uniprotkb:SLA2(gene name)|psi-mi:SLA2(display_short)|uniprotkb:END4(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:UFG1(gene name synonym)|uniprotkb:YNL243W(locus name)|uniprotkb:N1102(orf name)|uniprotkb:Transmembrane protein MOP2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324360|imex:IM-14275-950 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012912.1|sgd:S000001496|dip:DIP-1819N|mint:P33204|ensemblfungi:YKL013C(gene)|ensemblfungi:YKL013C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 refseq:NP_014156.2|sgd:S000005187|ensemblfungi:YNL243W(gene)|ensemblfungi:YNL243W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002558(I/LWEQ)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR030224|interpro:IPR035964|rcsb pdb:5AHV|rcsb pdb:7B2L|reactome:R-SCE-8856828|dip:DIP-973N|mint:P33338 psi-mi:"MI:0469"(intact) crc64:B80CBD6642E39C1C crc64:E592E09D8040C0E9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wscMsqBK/3Rsah+2vbE3REyYhhg559292 rogid:HdBIyI4al1me0fjpCDcLIkwHEhI559292 intact-crc:97DED3F9A565C3F8|rigid:FrwIZ0EMPMQbCdNdvIT3FcWT748 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37370 uniprotkb:P33338 intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C intact:EBI-17323|uniprotkb:Q02434|uniprotkb:D6W0V0|ensemblfungi:YNL243W psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:sla2_yeast(display_long)|uniprotkb:SLA2(gene name)|psi-mi:SLA2(display_short)|uniprotkb:END4(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:UFG1(gene name synonym)|uniprotkb:YNL243W(locus name)|uniprotkb:N1102(orf name)|uniprotkb:Transmembrane protein MOP2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324371|imex:IM-14275-951 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370 refseq:NP_014156.2|sgd:S000005187|ensemblfungi:YNL243W(gene)|ensemblfungi:YNL243W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002558(I/LWEQ)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR030224|interpro:IPR035964|rcsb pdb:5AHV|rcsb pdb:7B2L|reactome:R-SCE-8856828|dip:DIP-973N|mint:P33338 psi-mi:"MI:0469"(intact) crc64:24C7522D5B1CA1C8 crc64:E592E09D8040C0E9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 rogid:HdBIyI4al1me0fjpCDcLIkwHEhI559292 intact-crc:5318B095FBF8D8F6|rigid:1aJa+VExAwKGIFgC3PwwTfB+cRI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33338 uniprotkb:P38328 intact:EBI-17323|uniprotkb:Q02434|uniprotkb:D6W0V0|ensemblfungi:YNL243W intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C psi-mi:sla2_yeast(display_long)|uniprotkb:SLA2(gene name)|psi-mi:SLA2(display_short)|uniprotkb:END4(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:UFG1(gene name synonym)|uniprotkb:YNL243W(locus name)|uniprotkb:N1102(orf name)|uniprotkb:Transmembrane protein MOP2(gene name synonym) psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324382|imex:IM-14275-952 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014156.2|sgd:S000005187|ensemblfungi:YNL243W(gene)|ensemblfungi:YNL243W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002558(I/LWEQ)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR030224|interpro:IPR035964|rcsb pdb:5AHV|rcsb pdb:7B2L|reactome:R-SCE-8856828|dip:DIP-973N|mint:P33338 sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:E592E09D8040C0E9 crc64:D75C6BB8EC35EEDF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HdBIyI4al1me0fjpCDcLIkwHEhI559292 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 intact-crc:E93788E08D80CCA0|rigid:qEL8rqVGb7wxULiooM1quDsKDkk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39013 uniprotkb:P33338 intact:EBI-6460|intact:EBI-33854|intact:EBI-30557|intact:EBI-31021|uniprotkb:D6W195|uniprotkb:Q8TFC4|uniprotkb:Q8TFD0|uniprotkb:Q8TG51|ensemblfungi:YNL084C intact:EBI-17323|uniprotkb:Q02434|uniprotkb:D6W0V0|ensemblfungi:YNL243W psi-mi:end3_yeast(display_long)|uniprotkb:END3(gene name)|psi-mi:END3(display_short)|uniprotkb:YNL084C(locus name)|uniprotkb:N2307(orf name)|uniprotkb:Endocytosis protein 3(gene name synonym) psi-mi:sla2_yeast(display_long)|uniprotkb:SLA2(gene name)|psi-mi:SLA2(display_short)|uniprotkb:END4(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:UFG1(gene name synonym)|uniprotkb:YNL243W(locus name)|uniprotkb:N1102(orf name)|uniprotkb:Transmembrane protein MOP2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324393|imex:IM-14275-953 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014315.1|sgd:S000005028|mint:P39013|dip:DIP-2220N|ensemblfungi:YNL084C(gene)|ensemblfungi:YNL084C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0071944"(cell periphery)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR025604|reactome:R-SCE-416482|reactome:R-SCE-8856828|reactome:R-SCE-9013148|reactome:R-SCE-9013406 refseq:NP_014156.2|sgd:S000005187|ensemblfungi:YNL243W(gene)|ensemblfungi:YNL243W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002558(I/LWEQ)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR030224|interpro:IPR035964|rcsb pdb:5AHV|rcsb pdb:7B2L|reactome:R-SCE-8856828|dip:DIP-973N|mint:P33338 psi-mi:"MI:0469"(intact) - crc64:E592E09D8040C0E9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AvVFZdzX/4DkLet/+FGA8KrKfCw559292 rogid:HdBIyI4al1me0fjpCDcLIkwHEhI559292 intact-crc:9998B63202318821|rigid:UJDmfWXAlnvyAcZuo2pX1bQwsmw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40518 uniprotkb:P33338 intact:EBI-2750|uniprotkb:D6VVM2|ensemblfungi:YIL062C intact:EBI-17323|uniprotkb:Q02434|uniprotkb:D6W0V0|ensemblfungi:YNL243W psi-mi:arpc5_yeast(display_long)|uniprotkb:ARC15(gene name)|psi-mi:ARC15(display_short)|uniprotkb:Arp2/3 complex 16 kDa subunit(gene name synonym)|uniprotkb:YIL062C(locus name) psi-mi:sla2_yeast(display_long)|uniprotkb:SLA2(gene name)|psi-mi:SLA2(display_short)|uniprotkb:END4(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:UFG1(gene name synonym)|uniprotkb:YNL243W(locus name)|uniprotkb:N1102(orf name)|uniprotkb:Transmembrane protein MOP2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324404|imex:IM-14275-954 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012202.1|sgd:S000001324|dip:DIP-2101N|mint:P40518|ensemblfungi:YIL062C(gene)|ensemblfungi:YIL062C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR036743|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-6798695|reactome:R-SCE-8856828 refseq:NP_014156.2|sgd:S000005187|ensemblfungi:YNL243W(gene)|ensemblfungi:YNL243W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002558(I/LWEQ)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR030224|interpro:IPR035964|rcsb pdb:5AHV|rcsb pdb:7B2L|reactome:R-SCE-8856828|dip:DIP-973N|mint:P33338 psi-mi:"MI:0469"(intact) crc64:10E4DAF0F0801B02 crc64:E592E09D8040C0E9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iQ0mLisINMjXPulrRyDmrLcdpzU559292 rogid:HdBIyI4al1me0fjpCDcLIkwHEhI559292 intact-crc:B14434208B4C0CA6|rigid:94IoB9ljfFvIO7YaZ78ViWPpE+0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53731 uniprotkb:P33338 intact:EBI-2770|uniprotkb:D6W1L1|ensemblfungi:YNR035C intact:EBI-17323|uniprotkb:Q02434|uniprotkb:D6W0V0|ensemblfungi:YNL243W psi-mi:arpc2_yeast(display_long)|uniprotkb:ARC35(gene name)|psi-mi:ARC35(display_short)|uniprotkb:YNR035C(locus name)|uniprotkb:N3296(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym) psi-mi:sla2_yeast(display_long)|uniprotkb:SLA2(gene name)|psi-mi:SLA2(display_short)|uniprotkb:END4(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:UFG1(gene name synonym)|uniprotkb:YNL243W(locus name)|uniprotkb:N1102(orf name)|uniprotkb:Transmembrane protein MOP2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324415|imex:IM-14275-955 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014433.1|sgd:S000005318|dip:DIP-2304N|mint:P53731|ensemblfungi:YNR035C(gene)|ensemblfungi:YNR035C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072697"(protein localization to cell cortex)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 refseq:NP_014156.2|sgd:S000005187|ensemblfungi:YNL243W(gene)|ensemblfungi:YNL243W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002558(I/LWEQ)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR030224|interpro:IPR035964|rcsb pdb:5AHV|rcsb pdb:7B2L|reactome:R-SCE-8856828|dip:DIP-973N|mint:P33338 psi-mi:"MI:0469"(intact) crc64:9AF71A93688729F6 crc64:E592E09D8040C0E9 figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:URdgP2srz1O44fNGQh18L7bzC+c559292 rogid:HdBIyI4al1me0fjpCDcLIkwHEhI559292 intact-crc:FE0195324FB96249|rigid:BeMjNQ0PVnEFd5nx1ln4x4LZwgE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05933 uniprotkb:P33338 intact:EBI-2764|uniprotkb:D6VZ07|ensemblfungi:YLR370C intact:EBI-17323|uniprotkb:Q02434|uniprotkb:D6W0V0|ensemblfungi:YNL243W psi-mi:arpc3_yeast(display_long)|uniprotkb:ARC18(gene name)|psi-mi:ARC18(display_short)|uniprotkb:YLR370C(locus name)|uniprotkb:L8039.15(orf name)|uniprotkb:Arp2/3 complex 21 kDa subunit(gene name synonym) psi-mi:sla2_yeast(display_long)|uniprotkb:SLA2(gene name)|psi-mi:SLA2(display_short)|uniprotkb:END4(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:UFG1(gene name synonym)|uniprotkb:YNL243W(locus name)|uniprotkb:N1102(orf name)|uniprotkb:Transmembrane protein MOP2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324426|imex:IM-14275-956 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004362|refseq:NP_013474.3|dip:DIP-2218N|mint:Q05933|ensemblfungi:YLR370C(gene)|ensemblfungi:YLR370C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR007204(ARP2/3 complex, 21 kDa p21-Arc subunit)|interpro:IPR036753|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 refseq:NP_014156.2|sgd:S000005187|ensemblfungi:YNL243W(gene)|ensemblfungi:YNL243W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002558(I/LWEQ)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR030224|interpro:IPR035964|rcsb pdb:5AHV|rcsb pdb:7B2L|reactome:R-SCE-8856828|dip:DIP-973N|mint:P33338 psi-mi:"MI:0469"(intact) crc64:456EABC2B9CC4860 crc64:E592E09D8040C0E9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Fj4cwULcw1TK5uS1lJczcNc5gns559292 rogid:HdBIyI4al1me0fjpCDcLIkwHEhI559292 intact-crc:BC5A879A818C6712|rigid:MnngBkexXhP+ntKUpycfvEsYgv0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33338 uniprotkb:Q12446 intact:EBI-17323|uniprotkb:Q02434|uniprotkb:D6W0V0|ensemblfungi:YNL243W intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W psi-mi:sla2_yeast(display_long)|uniprotkb:SLA2(gene name)|psi-mi:SLA2(display_short)|uniprotkb:END4(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:UFG1(gene name synonym)|uniprotkb:YNL243W(locus name)|uniprotkb:N1102(orf name)|uniprotkb:Transmembrane protein MOP2(gene name synonym) psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324437|imex:IM-14275-957 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014156.2|sgd:S000005187|ensemblfungi:YNL243W(gene)|ensemblfungi:YNL243W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002558(I/LWEQ)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR030224|interpro:IPR035964|rcsb pdb:5AHV|rcsb pdb:7B2L|reactome:R-SCE-8856828|dip:DIP-973N|mint:P33338 refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446 psi-mi:"MI:0469"(intact) crc64:E592E09D8040C0E9 crc64:4488355563AA2645 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HdBIyI4al1me0fjpCDcLIkwHEhI559292 rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292 intact-crc:4CD45A4FCF57E9D6|rigid:lu1rH9tmBnjX2KZ6deSWdkKk9+s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33338 uniprotkb:Q6Q5K6 intact:EBI-17323|uniprotkb:Q02434|uniprotkb:D6W0V0|ensemblfungi:YNL243W intact:EBI-392766|ensemblfungi:YML058W-A|uniprotkb:D6VZB5 psi-mi:sla2_yeast(display_long)|uniprotkb:SLA2(gene name)|psi-mi:SLA2(display_short)|uniprotkb:END4(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:UFG1(gene name synonym)|uniprotkb:YNL243W(locus name)|uniprotkb:N1102(orf name)|uniprotkb:Transmembrane protein MOP2(gene name synonym) psi-mi:hug1_yeast(display_long)|uniprotkb:HUG1(gene name)|psi-mi:HUG1(display_short)|uniprotkb:YML058W-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324448|imex:IM-14275-958 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014156.2|sgd:S000005187|ensemblfungi:YNL243W(gene)|ensemblfungi:YNL243W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002558(I/LWEQ)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR030224|interpro:IPR035964|rcsb pdb:5AHV|rcsb pdb:7B2L|reactome:R-SCE-8856828|dip:DIP-973N|mint:P33338 ensemblfungi:YML058W-A(gene)|ensemblfungi:YML058W-A_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:1905117"(regulation of ribonucleoside-diphosphate reductase activity)|go:"GO:1990846"(ribonucleoside-diphosphate reductase inhibitor activity)|sgd:S000007472|refseq:NP_219498.1|mint:Q6Q5K6 psi-mi:"MI:0469"(intact) crc64:E592E09D8040C0E9 - figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HdBIyI4al1me0fjpCDcLIkwHEhI559292 rogid:x+quBrnP+8yql7JGQ1NK4j5ubbw559292 intact-crc:E76A7C4DFACE23DA|rigid:0aWvYqon7wfFySn6NMPIZr/CbLA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07278 uniprotkb:P33749 intact:EBI-9475|ensemblfungi:YIL033C|uniprotkb:D6VVP9 intact:EBI-11414|uniprotkb:P35726|ensemblfungi:YKL062W|uniprotkb:D6VXM5 psi-mi:kapr_yeast(display_long)|uniprotkb:YIL033C(locus name)|uniprotkb:BCY1(gene name)|psi-mi:BCY1(display_short)|uniprotkb:REG1(gene name synonym)|uniprotkb:SRA1(gene name synonym)|uniprotkb:Bypass of cyclase mutations protein 1(gene name synonym)|uniprotkb:Protein kinase A regulatory subunit(gene name synonym) psi-mi:msn4_yeast(display_long)|uniprotkb:MSN4(gene name)|psi-mi:MSN4(display_short)|uniprotkb:Multicopy suppressor of SNF1 protein 4(gene name synonym)|uniprotkb:YKL062W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324459|imex:IM-14275-959 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YIL033C(gene)|ensemblfungi:YIL033C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0030552"(cAMP binding)|go:"GO:0036278"(positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0061406"(positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|rcsb pdb:3OF1|rcsb pdb:6XQK|refseq:NP_012231.1|sgd:S000001295|mint:P07278|dip:DIP-551N ensemblfungi:YKL062W_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|ensemblfungi:YKL062W(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0042594"(response to starvation)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|sgd:S000001545|refseq:NP_012861.1|mint:P33749|dip:DIP-6574N psi-mi:"MI:0469"(intact) crc64:6D7D97D8E4340AF3 crc64:3A264FB37C82C385 figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rSJ37UFoFiaHqc/2W5eYNx1qpbg559292 rogid:5+O1tA1waJkSRBw/u5TJtgpBeDg559292 intact-crc:24A4E398FD581ACF|rigid:YTwioBzffHwYzW0ifg9GtyCa6Pw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33750 uniprotkb:P53874 intact:EBI-17651|uniprotkb:D6VXZ1|ensemblfungi:YLL011W intact:EBI-19873|uniprotkb:D6W101|ensemblfungi:YNL186W psi-mi:dca13_yeast(display_long)|uniprotkb:SOF1(gene name)|psi-mi:SOF1(display_short)|uniprotkb:YLL011W(locus name)|uniprotkb:L1339(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein SOF1(gene name synonym) psi-mi:ubp10_yeast(display_long)|uniprotkb:UBP10(gene name)|psi-mi:UBP10(display_short)|uniprotkb:YNL186W(locus name)|uniprotkb:N1619(orf name)|uniprotkb:Ubiquitin-specific-processing protease 10(gene name synonym)|uniprotkb:Deubiquitinating enzyme 10(gene name synonym)|uniprotkb:Disrupter of telomere silencing protein 4(gene name synonym)|uniprotkb:Ubiquitin thioesterase 10(gene name synonym)|uniprotkb:DOT4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324470|imex:IM-14275-960 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLL011W(gene)|ensemblfungi:YLL011W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR007287(Sof1-like protein)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_013090.1|sgd:S000003934|dip:DIP-746N|mint:P33750 refseq:NP_014213.2|sgd:S000005130|ensemblfungi:YNL186W(gene)|ensemblfungi:YNL186W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0043596"(nuclear replication fork)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|rcsb pdb:6RR0|dip:DIP-6664N|mint:P53874 psi-mi:"MI:0469"(intact) crc64:4B28371CC61DE7E4 - figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:stTLdABNsa3SvTkNOZBteSNAVJA559292 rogid:Z1rRAI9RLgHeGd7QwLbrf51v5LY559292 intact-crc:6CE6D0D2FD9960FF|rigid:sYA+XoKdgysA9fZqLKRil3nEkRw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P33767 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-12658|uniprotkb:D3DLP5|ensemblfungi:YEL002C psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:ostb_yeast(display_long)|uniprotkb:WBP1(gene name)|psi-mi:WBP1(display_short)|uniprotkb:Oligosaccharyl transferase subunit beta(gene name synonym)|uniprotkb:YEL002C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324481|imex:IM-14275-961 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 ensemblfungi:YEL002C(gene)|ensemblfungi:YEL002C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)|rcsb pdb:4J86|rcsb pdb:6C26|rcsb pdb:6EZN|reactome:R-SCE-6798695|refseq:NP_010914.3|sgd:S000000728|mint:P33767|dip:DIP-676N psi-mi:"MI:0469"(intact) - crc64:495DA76BE8A9B29A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:hSnp48laqjCzA32hSJblrQ/5q5E559292 intact-crc:20F9D084278F99B7|rigid:RYQiOGrfG6SRuRgLjP5Ycgh/EL0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33767 uniprotkb:P38694 intact:EBI-12658|uniprotkb:D3DLP5|ensemblfungi:YEL002C intact:EBI-24511|uniprotkb:D3DKY6|ensemblfungi:YHR039C psi-mi:ostb_yeast(display_long)|uniprotkb:WBP1(gene name)|psi-mi:WBP1(display_short)|uniprotkb:Oligosaccharyl transferase subunit beta(gene name synonym)|uniprotkb:YEL002C(locus name) psi-mi:msc7_yeast(display_long)|uniprotkb:MSC7(gene name)|psi-mi:MSC7(display_short)|uniprotkb:Meiotic sister-chromatid recombination protein 7(gene name synonym)|uniprotkb:YHR039C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324492|imex:IM-14275-962 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YEL002C(gene)|ensemblfungi:YEL002C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)|rcsb pdb:4J86|rcsb pdb:6C26|rcsb pdb:6EZN|reactome:R-SCE-6798695|refseq:NP_010914.3|sgd:S000000728|mint:P33767|dip:DIP-676N refseq:NP_011904.1|sgd:S000001081|dip:DIP-1878N|mint:P38694|ensemblfungi:YHR039C(gene)|ensemblfungi:YHR039C_mRNA(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007131"(reciprocal meiotic recombination)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510 psi-mi:"MI:0469"(intact) crc64:495DA76BE8A9B29A - figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hSnp48laqjCzA32hSJblrQ/5q5E559292 rogid:p2xtb6/xYI/jfPNtO6JRZs+5t6I559292 intact-crc:D74C9C1A8ED62AA0|rigid:DPY+agNeovQHEIjZ6ALqiY/NHtA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33767 uniprotkb:P54837 intact:EBI-12658|uniprotkb:D3DLP5|ensemblfungi:YEL002C intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:ostb_yeast(display_long)|uniprotkb:WBP1(gene name)|psi-mi:WBP1(display_short)|uniprotkb:Oligosaccharyl transferase subunit beta(gene name synonym)|uniprotkb:YEL002C(locus name) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324503|imex:IM-14275-963 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YEL002C(gene)|ensemblfungi:YEL002C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)|rcsb pdb:4J86|rcsb pdb:6C26|rcsb pdb:6EZN|reactome:R-SCE-6798695|refseq:NP_010914.3|sgd:S000000728|mint:P33767|dip:DIP-676N refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:495DA76BE8A9B29A - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hSnp48laqjCzA32hSJblrQ/5q5E559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:01C88C751B88E2E4|rigid:5MC/i0+zzGX1y9MnLUjqcUliL40 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:P33767 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-12658|uniprotkb:D3DLP5|ensemblfungi:YEL002C psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:ostb_yeast(display_long)|uniprotkb:WBP1(gene name)|psi-mi:WBP1(display_short)|uniprotkb:Oligosaccharyl transferase subunit beta(gene name synonym)|uniprotkb:YEL002C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324514|imex:IM-14275-964 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 ensemblfungi:YEL002C(gene)|ensemblfungi:YEL002C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)|rcsb pdb:4J86|rcsb pdb:6C26|rcsb pdb:6EZN|reactome:R-SCE-6798695|refseq:NP_010914.3|sgd:S000000728|mint:P33767|dip:DIP-676N psi-mi:"MI:0469"(intact) - crc64:495DA76BE8A9B29A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:hSnp48laqjCzA32hSJblrQ/5q5E559292 intact-crc:1B51985DB19D1552|rigid:IHawpkl0wihg/AQgwOJftdDJSLw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06144 uniprotkb:P33767 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W intact:EBI-12658|uniprotkb:D3DLP5|ensemblfungi:YEL002C psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:ostb_yeast(display_long)|uniprotkb:WBP1(gene name)|psi-mi:WBP1(display_short)|uniprotkb:Oligosaccharyl transferase subunit beta(gene name synonym)|uniprotkb:YEL002C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324525|imex:IM-14275-965 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 ensemblfungi:YEL002C(gene)|ensemblfungi:YEL002C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)|rcsb pdb:4J86|rcsb pdb:6C26|rcsb pdb:6EZN|reactome:R-SCE-6798695|refseq:NP_010914.3|sgd:S000000728|mint:P33767|dip:DIP-676N psi-mi:"MI:0469"(intact) crc64:2F474503CAB7C195 crc64:495DA76BE8A9B29A figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 rogid:hSnp48laqjCzA32hSJblrQ/5q5E559292 intact-crc:58F9A19BD76E152A|rigid:q+YMiBsppxGMNH0vhvTEU1mpQ5E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40414 uniprotkb:P33892 intact:EBI-19419|uniprotkb:D6VVE8|ensemblfungi:YIL138C intact:EBI-7442|uniprotkb:D6VTV8|ensemblfungi:YGL195W psi-mi:tpm2_yeast(display_long)|uniprotkb:YIL138C(locus name)|uniprotkb:TPM2(gene name)|psi-mi:TPM2(display_short) psi-mi:gcn1_yeast(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:General control non-derepressible protein 1(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym)|uniprotkb:G1318(orf name)|uniprotkb:YGL195W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324536|imex:IM-14275-966 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001400|ensemblfungi:YIL138C(gene)|ensemblfungi:YIL138C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003786"(actin lateral binding)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005884"(actin filament)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|interpro:IPR000533(Tropomyosin)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007119"(budding cell isotropic bud growth)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0032432"(actin filament bundle)|refseq:NP_012128.3|dip:DIP-2201N|mint:P40414 sgd:S000003163|refseq:NP_011320.3|mint:P33892|dip:DIP-2344N|ensemblfungi:YGL195W(gene)|ensemblfungi:YGL195W_mRNA(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071264"(positive regulation of translational initiation in response to starvation)|go:"GO:0072755"(cellular response to benomyl)|go:"GO:0140469"(GCN2-mediated signaling)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1990451"(cellular stress response to acidic pH)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR022716|interpro:IPR033173|interpro:IPR034085 psi-mi:"MI:0469"(intact) - crc64:980FDD03753E9D1C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:/V6RhsoBaanxDVJ4SSAfev2tvnk559292 rogid:WPYtEB/xjy4g2cJFwhe+2teVYVk559292 intact-crc:16B9B51C859F4386|rigid:uBav6Ij2X4k1fI4F/0vTxx78XCc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33892 uniprotkb:Q03768 intact:EBI-7442|uniprotkb:D6VTV8|ensemblfungi:YGL195W intact:EBI-7618|uniprotkb:D6VSD4|ensemblfungi:YDR152W psi-mi:gcn1_yeast(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:General control non-derepressible protein 1(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym)|uniprotkb:G1318(orf name)|uniprotkb:YGL195W(locus name) psi-mi:gir2_yeast(display_long)|uniprotkb:GIR2(gene name)|psi-mi:GIR2(display_short)|uniprotkb:YDR152W(locus name)|uniprotkb:YD8358.08(orf name)|uniprotkb:DFRP2(gene name synonym)|uniprotkb:DRG family-regulatory protein 2(gene name synonym)|uniprotkb:Genetically interacts with ribosomal genes protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324547|imex:IM-14275-967 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003163|refseq:NP_011320.3|mint:P33892|dip:DIP-2344N|ensemblfungi:YGL195W(gene)|ensemblfungi:YGL195W_mRNA(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071264"(positive regulation of translational initiation in response to starvation)|go:"GO:0072755"(cellular response to benomyl)|go:"GO:0140469"(GCN2-mediated signaling)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1990451"(cellular stress response to acidic pH)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR022716|interpro:IPR033173|interpro:IPR034085 sgd:S000002559|refseq:NP_010436.3|mint:Q03768|dip:DIP-1751N|ensemblfungi:YDR152W(gene)|ensemblfungi:YDR152W_mRNA(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR006575(RWD)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR040213 psi-mi:"MI:0469"(intact) crc64:980FDD03753E9D1C crc64:CE09A067388638ED figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WPYtEB/xjy4g2cJFwhe+2teVYVk559292 rogid:2gb8Bf2IGl8RoOmNcIvEMlmgeTE559292 intact-crc:D616EE5536D99408|rigid:6WIHplwyY+5EbN3smomI0jyxfR4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12043 uniprotkb:P33892 intact:EBI-34845|uniprotkb:Q7LH13|uniprotkb:D6W2E4|ensemblfungi:YOR081C intact:EBI-7442|uniprotkb:D6VTV8|ensemblfungi:YGL195W psi-mi:tgl5_yeast(display_long)|uniprotkb:TGL5(gene name)|psi-mi:TGL5(display_short)|uniprotkb:STC2(gene name synonym)|uniprotkb:YOR29-32(orf name)|uniprotkb:YOR2964C(orf name)|uniprotkb:YOR081C(locus name)|uniprotkb:Lipase 5(gene name synonym) psi-mi:gcn1_yeast(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:General control non-derepressible protein 1(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym)|uniprotkb:G1318(orf name)|uniprotkb:YGL195W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324558|imex:IM-14275-968 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014724.1|sgd:S000005607|mint:Q12043|dip:DIP-6280N|ensemblfungi:YOR081C(gene)|ensemblfungi:YOR081C_mRNA(transcript)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042171"(lysophosphatidic acid acyltransferase activity)|interpro:IPR002641(Patatin)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR021771 sgd:S000003163|refseq:NP_011320.3|mint:P33892|dip:DIP-2344N|ensemblfungi:YGL195W(gene)|ensemblfungi:YGL195W_mRNA(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071264"(positive regulation of translational initiation in response to starvation)|go:"GO:0072755"(cellular response to benomyl)|go:"GO:0140469"(GCN2-mediated signaling)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1990451"(cellular stress response to acidic pH)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR022716|interpro:IPR033173|interpro:IPR034085 psi-mi:"MI:0469"(intact) - crc64:980FDD03753E9D1C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ccHxygbWfyyQXKaSbOL4iYhikms559292 rogid:WPYtEB/xjy4g2cJFwhe+2teVYVk559292 intact-crc:AB4CA839EC6CB820|rigid:BiXk6iF/7hzXumwzLJcqJoTdLhE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32319 uniprotkb:P34110 intact:EBI-13123|uniprotkb:D6VPY3|ensemblfungi:YBL017C intact:EBI-20415|uniprotkb:D6VW33|ensemblfungi:YJL154C psi-mi:vps10_yeast(display_long)|uniprotkb:PEP1(gene name)|psi-mi:PEP1(display_short)|uniprotkb:Vacuolar carboxypeptidase sorting receptor VPS10(gene name synonym)|uniprotkb:Carboxypeptidase Y receptor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 1(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 1(gene name synonym)|uniprotkb:Sortilin VPS10(gene name synonym)|uniprotkb:VPS10(gene name synonym)|uniprotkb:VPT1(gene name synonym)|uniprotkb:YBL03.22(orf name)|uniprotkb:YBL0302(orf name)|uniprotkb:YBL017C(locus name) psi-mi:vps35_yeast(display_long)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:Vacuolar protein-targeting protein 7(gene name synonym)|uniprotkb:VPT7(gene name synonym)|uniprotkb:J0580(orf name)|uniprotkb:YJL154C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324569|imex:IM-14275-969 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009536.1|sgd:S000000113|mint:P32319|dip:DIP-5900N|ensemblfungi:YBL017C(gene)|ensemblfungi:YBL017C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000423"(mitophagy)|go:"GO:0000425"(pexophagy)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048203"(vesicle targeting, trans-Golgi to endosome)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR036278 refseq:NP_012381.1|sgd:S000003690|ensemblfungi:YJL154C(gene)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1904377"(positive regulation of protein localization to cell periphery)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR042491|reactome:R-SCE-3238698|ensemblfungi:YJL154C_mRNA(transcript)|dip:DIP-1743N|mint:P34110 psi-mi:"MI:0469"(intact) crc64:C778A0400612ECF4 crc64:DE1BC57B9DFB606E figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dYYsekAaDw4SzmEUSe5tYb5a43M559292 rogid:5KBi/lSF+BsMyg9ulP9eLCp2xCc559292 intact-crc:39477F60581B9BF4|rigid:bZu22rFnzQFmEIGsFbe5AVLYp2U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32913 uniprotkb:P34110 intact:EBI-20366|uniprotkb:Q12279|uniprotkb:D6W2J0|ensemblfungi:YOR132W intact:EBI-20415|uniprotkb:D6VW33|ensemblfungi:YJL154C psi-mi:vps17_yeast(display_long)|uniprotkb:VPS17(gene name)|psi-mi:VPS17(display_short)|uniprotkb:PEP21(gene name synonym)|uniprotkb:YOR132W(locus name)|uniprotkb:O3314(orf name)|uniprotkb:YOR3314W(orf name)|uniprotkb:Carboxypeptidase Y-deficient protein 21(gene name synonym) psi-mi:vps35_yeast(display_long)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:Vacuolar protein-targeting protein 7(gene name synonym)|uniprotkb:VPT7(gene name synonym)|uniprotkb:J0580(orf name)|uniprotkb:YJL154C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324580|imex:IM-14275-970 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005658|refseq:NP_014775.3|ensemblfungi:YOR132W(gene)|ensemblfungi:YOR132W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR001683(Phox-like)|interpro:IPR014461(Vacuolar protein sorting-associated protein Vps17)|interpro:IPR027267|interpro:IPR036871|interpro:IPR037907|dip:DIP-1739N|mint:P32913 refseq:NP_012381.1|sgd:S000003690|ensemblfungi:YJL154C(gene)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1904377"(positive regulation of protein localization to cell periphery)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR042491|reactome:R-SCE-3238698|ensemblfungi:YJL154C_mRNA(transcript)|dip:DIP-1743N|mint:P34110 psi-mi:"MI:0469"(intact) crc64:C709968468144A50 crc64:DE1BC57B9DFB606E figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:X5nNIyX3T0PYprdyJaxVnc8RoR8559292 rogid:5KBi/lSF+BsMyg9ulP9eLCp2xCc559292 intact-crc:A9E2B54CC908F85F|rigid:se9RuRXrDe89wVOsPD38b6hdj2s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34110 uniprotkb:P34110 intact:EBI-20415|uniprotkb:D6VW33|ensemblfungi:YJL154C intact:EBI-20415|uniprotkb:D6VW33|ensemblfungi:YJL154C psi-mi:vps35_yeast(display_long)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:Vacuolar protein-targeting protein 7(gene name synonym)|uniprotkb:VPT7(gene name synonym)|uniprotkb:J0580(orf name)|uniprotkb:YJL154C(locus name) psi-mi:vps35_yeast(display_long)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:Vacuolar protein-targeting protein 7(gene name synonym)|uniprotkb:VPT7(gene name synonym)|uniprotkb:J0580(orf name)|uniprotkb:YJL154C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324591|imex:IM-14275-971 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012381.1|sgd:S000003690|ensemblfungi:YJL154C(gene)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1904377"(positive regulation of protein localization to cell periphery)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR042491|reactome:R-SCE-3238698|ensemblfungi:YJL154C_mRNA(transcript)|dip:DIP-1743N|mint:P34110 refseq:NP_012381.1|sgd:S000003690|ensemblfungi:YJL154C(gene)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1904377"(positive regulation of protein localization to cell periphery)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR042491|reactome:R-SCE-3238698|ensemblfungi:YJL154C_mRNA(transcript)|dip:DIP-1743N|mint:P34110 psi-mi:"MI:0469"(intact) crc64:DE1BC57B9DFB606E crc64:DE1BC57B9DFB606E figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5KBi/lSF+BsMyg9ulP9eLCp2xCc559292 rogid:5KBi/lSF+BsMyg9ulP9eLCp2xCc559292 intact-crc:805E243F10CA9454|rigid:KiooAFSaZAo6FvoQUZt40tuE8k8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34110 uniprotkb:P40959 intact:EBI-20415|uniprotkb:D6VW33|ensemblfungi:YJL154C intact:EBI-11636|ensemblfungi:YMR004W|uniprotkb:D6VZH9 psi-mi:vps35_yeast(display_long)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:Vacuolar protein-targeting protein 7(gene name synonym)|uniprotkb:VPT7(gene name synonym)|uniprotkb:J0580(orf name)|uniprotkb:YJL154C(locus name) psi-mi:mvp1_yeast(display_long)|uniprotkb:MVP1(gene name)|psi-mi:MVP1(display_short)|uniprotkb:YM8270.06(orf name)|uniprotkb:YMR004W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324602|imex:IM-14275-972 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012381.1|sgd:S000003690|ensemblfungi:YJL154C(gene)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1904377"(positive regulation of protein localization to cell periphery)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR042491|reactome:R-SCE-3238698|ensemblfungi:YJL154C_mRNA(transcript)|dip:DIP-1743N|mint:P34110 ensemblfungi:YMR004W(gene)|ensemblfungi:YMR004W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0016020"(membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001683(Phox-like)|interpro:IPR028662|interpro:IPR035704|interpro:IPR036871|rcsb pdb:6Q0X|refseq:NP_013717.1|sgd:S000004606|mint:P40959|dip:DIP-1764N psi-mi:"MI:0469"(intact) crc64:DE1BC57B9DFB606E - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5KBi/lSF+BsMyg9ulP9eLCp2xCc559292 rogid:3IrMPCYXP5yb2l52Uhu2DiEuNdI559292 intact-crc:26A81604A1396F19|rigid:HCqbi+nnCLhkBVlyoNGdKvFUqR8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92331 uniprotkb:P34110 intact:EBI-20483|uniprotkb:Q08483|uniprotkb:D6W2D1|uniprotkb:E9P8U6|ensemblfungi:YOR069W intact:EBI-20415|uniprotkb:D6VW33|ensemblfungi:YJL154C psi-mi:vps5_yeast(display_long)|uniprotkb:VPS5(gene name)|psi-mi:VPS5(display_short)|uniprotkb:GRD2(gene name synonym)|uniprotkb:PEP10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 5(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 10(gene name synonym)|uniprotkb:VPT5(gene name synonym)|uniprotkb:YOR29-20(orf name)|uniprotkb:YOR069W(locus name) psi-mi:vps35_yeast(display_long)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:Vacuolar protein-targeting protein 7(gene name synonym)|uniprotkb:VPT7(gene name synonym)|uniprotkb:J0580(orf name)|uniprotkb:YJL154C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324613|imex:IM-14275-973 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014712.2|sgd:S000005595|ensemblfungi:YOR069W(gene)|ensemblfungi:YOR069W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0005768"(endosome)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|interpro:IPR001683(Phox-like)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028648|interpro:IPR035803|interpro:IPR036871|interpro:IPR037868|dip:DIP-1740N|mint:Q92331 refseq:NP_012381.1|sgd:S000003690|ensemblfungi:YJL154C(gene)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1904377"(positive regulation of protein localization to cell periphery)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR042491|reactome:R-SCE-3238698|ensemblfungi:YJL154C_mRNA(transcript)|dip:DIP-1743N|mint:P34110 psi-mi:"MI:0469"(intact) - crc64:DE1BC57B9DFB606E figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5aPSkQUJV1sfIc9Ql+wMP74Y3QI559292 rogid:5KBi/lSF+BsMyg9ulP9eLCp2xCc559292 intact-crc:4D4A6E2BEAE64BFE|rigid:ZBMmFPbxBT13yMoqkE82iYcfCXs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34160 uniprotkb:Q08920 intact:EBI-745|uniprotkb:D6VZU8|ensemblfungi:YMR125W intact:EBI-33556|uniprotkb:D6W3J0|ensemblfungi:YPL178W psi-mi:ncbp1_yeast(display_long)|uniprotkb:STO1(gene name)|psi-mi:STO1(display_short)|uniprotkb:CBC1(gene name synonym)|uniprotkb:SUT1(gene name synonym)|uniprotkb:YM8564.07(orf name)|uniprotkb:YM9553.01(orf name)|uniprotkb:YMR125W(locus name)|uniprotkb:80 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:CBP80(gene name synonym)|uniprotkb:GCR3(gene name synonym)|uniprotkb:Glycolysis regulation protein 3(gene name synonym)|uniprotkb:Suppressor of TOP1 protein(gene name synonym)|uniprotkb:Protein SUT1(gene name synonym) psi-mi:ncbp2_yeast(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:CBC2(gene name)|psi-mi:CBC2(display_short)|uniprotkb:SAE1(gene name synonym)|uniprotkb:CBP20(gene name synonym)|uniprotkb:MUD13(gene name synonym)|uniprotkb:YPL178W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324624|imex:IM-14275-974 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013844.2|sgd:S000004732|dip:DIP-4434N|mint:P34160|ensemblfungi:YMR125W(gene)|ensemblfungi:YMR125W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000243"(commitment complex)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR015172(MIF4G-like, type 1)|interpro:IPR015174(MIF4G-like, type 2)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027159|rcsb pdb:3UKY|rcsb pdb:6N7P|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-72086|reactome:R-SCE-77595|reactome:R-SCE-975956|reactome:R-SCE-975957 refseq:NP_015147.1|sgd:S000006099|mint:Q08920|dip:DIP-1117N|ensemblfungi:YPL178W(gene)|ensemblfungi:YPL178W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000243"(commitment complex)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR027157|interpro:IPR034148|interpro:IPR035979|rcsb pdb:6N7P|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-72086|reactome:R-SCE-77595|reactome:R-SCE-975956|reactome:R-SCE-975957 psi-mi:"MI:0469"(intact) crc64:EDD04907BDC9207D crc64:B77E93BDDC429160 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UtRme+MHDQ/glSCLJwYKJjHV+Uc559292 rogid:dkwkoyUFuzsrTsblimYpNFXkKuk559292 intact-crc:17B5F325A146C604|rigid:so4eJvRGc42S/E6LUDQc9F7iRq4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34163 uniprotkb:P14359 intact:EBI-19177|uniprotkb:D6VX56|ensemblfungi:YKL140W intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:tgl1_yeast(display_long)|uniprotkb:TGL1(gene name)|psi-mi:TGL1(display_short)|uniprotkb:YKL140W(locus name)|uniprotkb:YKL5(orf name)|uniprotkb:Triglyceride lipase-cholesterol esterase 1(gene name synonym) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324635|imex:IM-14275-975 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012782.1|sgd:S000001623|ensemblfungi:YKL140W(gene)|ensemblfungi:YKL140W_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR029058|dip:DIP-6306N|mint:P34163 refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) crc64:32D1F230701CB083 crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:/f3560MDciadPqvZ0iY9e9oVBH8559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:91EBD3A3140B4975|rigid:FzNesM7OEzXFgkW8WYy2mCmm16k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28625 uniprotkb:P34163 intact:EBI-27313|uniprotkb:D6VZX3|ensemblfungi:YMR152W intact:EBI-19177|uniprotkb:D6VX56|ensemblfungi:YKL140W psi-mi:yim1_yeast(display_long)|uniprotkb:YIM1(gene name)|psi-mi:YIM1(display_short)|uniprotkb:YM8520.01(orf name)|uniprotkb:YM9375.22(orf name)|uniprotkb:YMR152W(locus name) psi-mi:tgl1_yeast(display_long)|uniprotkb:TGL1(gene name)|psi-mi:TGL1(display_short)|uniprotkb:YKL140W(locus name)|uniprotkb:YKL5(orf name)|uniprotkb:Triglyceride lipase-cholesterol esterase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324646|imex:IM-14275-976 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013872.1|sgd:S000004760|mint:P28625|dip:DIP-4467N|ensemblfungi:YMR152W(gene)|ensemblfungi:YMR152W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0018455"("alcohol dehydrogenase [NAD(P)+] activity")|interpro:IPR011032(GroES-like)|interpro:IPR036291 refseq:NP_012782.1|sgd:S000001623|ensemblfungi:YKL140W(gene)|ensemblfungi:YKL140W_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR029058|dip:DIP-6306N|mint:P34163 psi-mi:"MI:0469"(intact) - crc64:32D1F230701CB083 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pbDN6nTnpBtIqdFE6/CjlI12o04559292 rogid:/f3560MDciadPqvZ0iY9e9oVBH8559292 intact-crc:3C54F329B605F928|rigid:vneKT3ipOouEXJoFdLOUoPwz97o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34163 uniprotkb:P34163 intact:EBI-19177|uniprotkb:D6VX56|ensemblfungi:YKL140W intact:EBI-19177|uniprotkb:D6VX56|ensemblfungi:YKL140W psi-mi:tgl1_yeast(display_long)|uniprotkb:TGL1(gene name)|psi-mi:TGL1(display_short)|uniprotkb:YKL140W(locus name)|uniprotkb:YKL5(orf name)|uniprotkb:Triglyceride lipase-cholesterol esterase 1(gene name synonym) psi-mi:tgl1_yeast(display_long)|uniprotkb:TGL1(gene name)|psi-mi:TGL1(display_short)|uniprotkb:YKL140W(locus name)|uniprotkb:YKL5(orf name)|uniprotkb:Triglyceride lipase-cholesterol esterase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324657|imex:IM-14275-977 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012782.1|sgd:S000001623|ensemblfungi:YKL140W(gene)|ensemblfungi:YKL140W_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR029058|dip:DIP-6306N|mint:P34163 refseq:NP_012782.1|sgd:S000001623|ensemblfungi:YKL140W(gene)|ensemblfungi:YKL140W_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR029058|dip:DIP-6306N|mint:P34163 psi-mi:"MI:0469"(intact) crc64:32D1F230701CB083 crc64:32D1F230701CB083 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:/f3560MDciadPqvZ0iY9e9oVBH8559292 rogid:/f3560MDciadPqvZ0iY9e9oVBH8559292 intact-crc:C92C166954977F3D|rigid:dMAZdSMp7V20SbTxBSsfK7TqDUE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35196 uniprotkb:P34163 intact:EBI-14943|uniprotkb:D6VQ03|ensemblfungi:YBR002C intact:EBI-19177|uniprotkb:D6VX56|ensemblfungi:YKL140W psi-mi:rer2_yeast(display_long)|uniprotkb:"Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific)"(gene name synonym)|uniprotkb:YBR0107(orf name)|uniprotkb:RER2(gene name)|psi-mi:RER2(display_short)|uniprotkb:YBR002C(locus name) psi-mi:tgl1_yeast(display_long)|uniprotkb:TGL1(gene name)|psi-mi:TGL1(display_short)|uniprotkb:YKL140W(locus name)|uniprotkb:YKL5(orf name)|uniprotkb:Triglyceride lipase-cholesterol esterase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324668|imex:IM-14275-978 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036424|refseq:NP_009556.1|sgd:S000000206|interpro:IPR001441(Di-trans-poly-cis-decaprenylcistransferase)|interpro:IPR018520|ensemblfungi:YBR002C(gene)|ensemblfungi:YBR002C_mRNA(transcript)|go:"GO:0002094"(polyprenyltransferase activity)|go:"GO:0004659"(prenyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016094"(polyprenol biosynthetic process)|go:"GO:0019408"(dolichol biosynthetic process)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0045547"(dehydrodolichyl diphosphate synthase activity)|go:"GO:1904423"(dehydrodolichyl diphosphate synthase complex)|reactome:R-SCE-446199|mint:P35196 refseq:NP_012782.1|sgd:S000001623|ensemblfungi:YKL140W(gene)|ensemblfungi:YKL140W_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR029058|dip:DIP-6306N|mint:P34163 psi-mi:"MI:0469"(intact) - crc64:32D1F230701CB083 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:gVl9E/6GKqKsUp/5VLdT5XGbjUM559292 rogid:/f3560MDciadPqvZ0iY9e9oVBH8559292 intact-crc:6BAD87E09C6F1176|rigid:lkz6fh90LH0RCutd4xsOtJojkTc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38225 uniprotkb:P34163 intact:EBI-6819|uniprotkb:O60021|uniprotkb:Q86ZS3|uniprotkb:D6VQ41|ensemblfungi:YBR041W intact:EBI-19177|uniprotkb:D6VX56|ensemblfungi:YKL140W psi-mi:fat1_yeast(display_long)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:Very-long-chain acyl-CoA synthetase(gene name synonym)|uniprotkb:YBR0411(orf name)|uniprotkb:YBR041W(locus name) psi-mi:tgl1_yeast(display_long)|uniprotkb:TGL1(gene name)|psi-mi:TGL1(display_short)|uniprotkb:YKL140W(locus name)|uniprotkb:YKL5(orf name)|uniprotkb:Triglyceride lipase-cholesterol esterase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324679|imex:IM-14275-979 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009597.2|sgd:S000000245|mint:P38225|dip:DIP-5048N|ensemblfungi:YBR041W(gene)|ensemblfungi:YBR041W_mRNA(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0071944"(cell periphery)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR030310|interpro:IPR042099|reactome:R-SCE-159418|reactome:R-SCE-193368|reactome:R-SCE-193775|reactome:R-SCE-389599|reactome:R-SCE-6798695|reactome:R-SCE-804914|reactome:R-SCE-9033241 refseq:NP_012782.1|sgd:S000001623|ensemblfungi:YKL140W(gene)|ensemblfungi:YKL140W_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR029058|dip:DIP-6306N|mint:P34163 psi-mi:"MI:0469"(intact) crc64:509A5DEDDEE98823 crc64:32D1F230701CB083 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mGjvEcQ/ZVHp/P+89KaQ7DrjcQg559292 rogid:/f3560MDciadPqvZ0iY9e9oVBH8559292 intact-crc:5F30E7D92126AC1A|rigid:Ce8k0pQ1ir65y16X8YUGif0PKHI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38604 uniprotkb:P34163 intact:EBI-6572|uniprotkb:Q92327|uniprotkb:D3DL21|ensemblfungi:YHR072W intact:EBI-19177|uniprotkb:D6VX56|ensemblfungi:YKL140W psi-mi:erg7_yeast(display_long)|uniprotkb:Oxidosqualene--lanosterol cyclase(gene name synonym)|uniprotkb:2,3-epoxysqualene--lanosterol cyclase(gene name synonym)|uniprotkb:YHR072W(locus name)|uniprotkb:ERG7(gene name)|psi-mi:ERG7(display_short) psi-mi:tgl1_yeast(display_long)|uniprotkb:TGL1(gene name)|psi-mi:TGL1(display_short)|uniprotkb:YKL140W(locus name)|uniprotkb:YKL5(orf name)|uniprotkb:Triglyceride lipase-cholesterol esterase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324690|imex:IM-14275-980 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011939.2|sgd:S000001114|mint:P38604|dip:DIP-8319N|ensemblfungi:YHR072W(gene)|ensemblfungi:YHR072W_mRNA(transcript)|go:"GO:0000250"(lanosterol synthase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016104"(triterpenoid biosynthetic process)|go:"GO:0042300"(beta-amyrin synthase activity)|interpro:IPR002365(Terpene synthase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR018333|interpro:IPR032696|interpro:IPR032697|reactome:R-SCE-191273 refseq:NP_012782.1|sgd:S000001623|ensemblfungi:YKL140W(gene)|ensemblfungi:YKL140W_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR029058|dip:DIP-6306N|mint:P34163 psi-mi:"MI:0469"(intact) - crc64:32D1F230701CB083 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zqDPA3GvKWkMTmH97TcdF8HOHBU559292 rogid:/f3560MDciadPqvZ0iY9e9oVBH8559292 intact-crc:6F73E00D64018D23|rigid:fKfBzht5YqLnBTqm0oLQMwtIeMw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40471 uniprotkb:P34163 intact:EBI-25213|uniprotkb:D6VVG3|ensemblfungi:YIL124W intact:EBI-19177|uniprotkb:D6VX56|ensemblfungi:YKL140W psi-mi:ayr1_yeast(display_long)|uniprotkb:AYR1(gene name)|psi-mi:AYR1(display_short)|uniprotkb:Acylglycerone-phosphate reductase(gene name synonym)|uniprotkb:1-acyl DHAP reductase(gene name synonym)|uniprotkb:Acyl/alkyl DHAP reductase(gene name synonym)|uniprotkb:GBG1(gene name synonym)|uniprotkb:Triacylglycerol lipase AYR1(gene name synonym)|uniprotkb:YIL124W(locus name) psi-mi:tgl1_yeast(display_long)|uniprotkb:TGL1(gene name)|psi-mi:TGL1(display_short)|uniprotkb:YKL140W(locus name)|uniprotkb:YKL5(orf name)|uniprotkb:Triglyceride lipase-cholesterol esterase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324701|imex:IM-14275-981 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001386|refseq:NP_012142.3|mint:P40471|dip:DIP-4614N|ensemblfungi:YIL124W(gene)|ensemblfungi:YIL124W_mRNA(transcript)|go:"GO:0000140"(acylglycerone-phosphate reductase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0102566"(1-acyl dihydroxyacetone phosphate reductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291 refseq:NP_012782.1|sgd:S000001623|ensemblfungi:YKL140W(gene)|ensemblfungi:YKL140W_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR029058|dip:DIP-6306N|mint:P34163 psi-mi:"MI:0469"(intact) crc64:B614C0E0B1FB0CE0 crc64:32D1F230701CB083 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WE4RmSXARj683MNUEsYGLis36Xo559292 rogid:/f3560MDciadPqvZ0iY9e9oVBH8559292 intact-crc:3E66E1BB64E72C8A|rigid:WpqwaCCK6XUJQ1miOROu/KD+IXI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34163 uniprotkb:Q12168 intact:EBI-19177|uniprotkb:D6VX56|ensemblfungi:YKL140W intact:EBI-32973|uniprotkb:Q07268|uniprotkb:D6VYD8|ensemblfungi:YLR144C psi-mi:tgl1_yeast(display_long)|uniprotkb:TGL1(gene name)|psi-mi:TGL1(display_short)|uniprotkb:YKL140W(locus name)|uniprotkb:YKL5(orf name)|uniprotkb:Triglyceride lipase-cholesterol esterase 1(gene name synonym) psi-mi:eng2_yeast(display_long)|uniprotkb:ACF2(gene name)|psi-mi:ACF2(display_short)|uniprotkb:YLR144C(locus name)|uniprotkb:Laminarinase-2(gene name synonym)|uniprotkb:ENG2(gene name synonym)|uniprotkb:PCA1(gene name synonym)|uniprotkb:L3180(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324712|imex:IM-14275-982 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012782.1|sgd:S000001623|ensemblfungi:YKL140W(gene)|ensemblfungi:YKL140W_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR029058|dip:DIP-6306N|mint:P34163 refseq:NP_013245.1|sgd:S000004134|mint:Q12168|dip:DIP-2889N|ensemblfungi:YLR144C(gene)|ensemblfungi:YLR144C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042973"(glucan endo-1,3-beta-D-glucosidase activity)|go:"GO:0052861"(glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group)|go:"GO:0052862"(glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group)|interpro:IPR005200(Glycoside hydrolase, family 81)|interpro:IPR040451|interpro:IPR040720 psi-mi:"MI:0469"(intact) crc64:32D1F230701CB083 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:/f3560MDciadPqvZ0iY9e9oVBH8559292 rogid:8STCUe6Ie2CnTTBMjY8wrld5h44559292 intact-crc:45E224EE6D3E14FC|rigid:PBC/p2+mDz1B1bB0ma/y8utSwCo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34217 uniprotkb:P06100 intact:EBI-21256|uniprotkb:D6VPU8|ensemblfungi:YBL051C intact:EBI-12153|uniprotkb:D6VRI6|ensemblfungi:YDL165W psi-mi:pin4_yeast(display_long)|uniprotkb:YBL051C(locus name)|uniprotkb:YBL0516(orf name)|uniprotkb:YBL0506(orf name)|uniprotkb:PIN4(gene name)|psi-mi:PIN4(display_short)|uniprotkb:MDT1(gene name synonym)|uniprotkb:Psi inducibility protein 4(gene name synonym) psi-mi:not2_yeast(display_long)|uniprotkb:CDC36(gene name)|psi-mi:CDC36(display_short)|uniprotkb:DNA19(gene name synonym)|uniprotkb:NOT2(gene name synonym)|uniprotkb:YDL165W(locus name)|uniprotkb:cell division cycle protein 36(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324723|imex:IM-14275-983 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009502.1|sgd:S000000147|mint:P34217|dip:DIP-1905N|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034069|interpro:IPR034186|interpro:IPR035979|rcsb pdb:2A0T|go:"GO:0071014"(post-mRNA release spliceosomal complex)|ensemblfungi:YBL051C(gene)|ensemblfungi:YBL051C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus") ensemblfungi:YDL165W(gene)|ensemblfungi:YDL165W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|refseq:NP_010116.1|sgd:S000002324|dip:DIP-590N|mint:P06100 psi-mi:"MI:0469"(intact) crc64:EA8EE581286436CB crc64:7D0B69657F791371 figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sr+hWCIssADTt8je3DmchPR6EiM559292 rogid:bOgpnRcqWbxkhHJg140qzPxIBJQ559292 intact-crc:7A1EA6DD4C0D2587|rigid:USRtNthRCYmPP9dgdhg9mnWgJMg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25655 uniprotkb:P34217 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-21256|uniprotkb:D6VPU8|ensemblfungi:YBL051C psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:pin4_yeast(display_long)|uniprotkb:YBL051C(locus name)|uniprotkb:YBL0516(orf name)|uniprotkb:YBL0506(orf name)|uniprotkb:PIN4(gene name)|psi-mi:PIN4(display_short)|uniprotkb:MDT1(gene name synonym)|uniprotkb:Psi inducibility protein 4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324734|imex:IM-14275-984 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 refseq:NP_009502.1|sgd:S000000147|mint:P34217|dip:DIP-1905N|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034069|interpro:IPR034186|interpro:IPR035979|rcsb pdb:2A0T|go:"GO:0071014"(post-mRNA release spliceosomal complex)|ensemblfungi:YBL051C(gene)|ensemblfungi:YBL051C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus") psi-mi:"MI:0469"(intact) crc64:5B2AE15BCF95E009 crc64:EA8EE581286436CB figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:Sr+hWCIssADTt8je3DmchPR6EiM559292 intact-crc:3C0AEDB6D0C57C96|rigid:g+B1xg23hb8QTQXA7mP1XIwVP2c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34909 uniprotkb:P34217 intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W intact:EBI-21256|uniprotkb:D6VPU8|ensemblfungi:YBL051C psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:pin4_yeast(display_long)|uniprotkb:YBL051C(locus name)|uniprotkb:YBL0516(orf name)|uniprotkb:YBL0506(orf name)|uniprotkb:PIN4(gene name)|psi-mi:PIN4(display_short)|uniprotkb:MDT1(gene name synonym)|uniprotkb:Psi inducibility protein 4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324745|imex:IM-14275-985 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 refseq:NP_009502.1|sgd:S000000147|mint:P34217|dip:DIP-1905N|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034069|interpro:IPR034186|interpro:IPR035979|rcsb pdb:2A0T|go:"GO:0071014"(post-mRNA release spliceosomal complex)|ensemblfungi:YBL051C(gene)|ensemblfungi:YBL051C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus") psi-mi:"MI:0469"(intact) crc64:8847084BD9BF48B7 crc64:EA8EE581286436CB figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 rogid:Sr+hWCIssADTt8je3DmchPR6EiM559292 intact-crc:FDCB91F457E9ED1F|rigid:avSgpitsSTxi2CabM4Nf9jF0jfc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53829 uniprotkb:P34217 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-21256|uniprotkb:D6VPU8|ensemblfungi:YBL051C psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:pin4_yeast(display_long)|uniprotkb:YBL051C(locus name)|uniprotkb:YBL0516(orf name)|uniprotkb:YBL0506(orf name)|uniprotkb:PIN4(gene name)|psi-mi:PIN4(display_short)|uniprotkb:MDT1(gene name synonym)|uniprotkb:Psi inducibility protein 4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324756|imex:IM-14275-986 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 refseq:NP_009502.1|sgd:S000000147|mint:P34217|dip:DIP-1905N|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034069|interpro:IPR034186|interpro:IPR035979|rcsb pdb:2A0T|go:"GO:0071014"(post-mRNA release spliceosomal complex)|ensemblfungi:YBL051C(gene)|ensemblfungi:YBL051C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus") psi-mi:"MI:0469"(intact) crc64:F3DBABE6AD3C7F3C crc64:EA8EE581286436CB figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:Sr+hWCIssADTt8je3DmchPR6EiM559292 intact-crc:7A788922FE23E87A|rigid:dzm0gj+IUtzunf0IAQHYkZMFYOE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34221 uniprotkb:P42938 intact:EBI-12805|uniprotkb:Q92330|uniprotkb:D6VPU4|ensemblfungi:YBL056W intact:EBI-23474|uniprotkb:D6VUY8|ensemblfungi:YGR205W psi-mi:pp2c3_yeast(display_long)|uniprotkb:PTC3(gene name)|psi-mi:PTC3(display_short)|uniprotkb:YBL0511(orf name)|uniprotkb:YBL0513(orf name)|uniprotkb:YBL056W(locus name) psi-mi:tda10_yeast(display_long)|uniprotkb:YGR205W(locus name)|uniprotkb:G7737(orf name)|uniprotkb:TDA10(gene name)|psi-mi:TDA10(display_short)|uniprotkb:Topoisomerase I damage affected protein 10(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324767|imex:IM-14275-987 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBL056W(gene)|ensemblfungi:YBL056W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C, manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|refseq:NP_009497.2|sgd:S000000152|mint:P34221|dip:DIP-3944N sgd:S000003437|refseq:NP_011721.3|dip:DIP-3866N|mint:P42938|ensemblfungi:YGR205W(gene)|ensemblfungi:YGR205W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008887"(glycerate kinase activity)|interpro:IPR027417|rcsb pdb:1ODF psi-mi:"MI:0469"(intact) crc64:70AC2707C7FA2122 crc64:EEB2DB5995122A29 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:igOpqJjHW4B7yBbADsYfaKaX/3M559292 rogid:y9ChOpTc15TkJh57cuCDZlQ228k559292 intact-crc:F23C8AA392B491A3|rigid:ZDozY/70pqPnryzbSlFfSUGehRs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34244 uniprotkb:P34244 intact:EBI-9771|uniprotkb:A2NP40|ensemblfungi:YKL101W|uniprotkb:D6VXI6 intact:EBI-9771|uniprotkb:A2NP40|ensemblfungi:YKL101W|uniprotkb:D6VXI6 psi-mi:hsl1_yeast(display_long)|uniprotkb:YKL453(orf name)|uniprotkb:YKL101W(locus name)|uniprotkb:HSL1(gene name)|psi-mi:HSL1(display_short) psi-mi:hsl1_yeast(display_long)|uniprotkb:YKL453(orf name)|uniprotkb:YKL101W(locus name)|uniprotkb:HSL1(gene name)|psi-mi:HSL1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324778|imex:IM-14275-988 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012821.2|sgd:S000001584|ensemblfungi:YKL101W(gene)|ensemblfungi:YKL101W_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044879"(mitotic morphogenesis checkpoint signaling)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902935"(protein localization to septin ring)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:5G04|rcsb pdb:5KHR|rcsb pdb:5L9T|rcsb pdb:5L9U|go:"GO:0000144"(cellular bud neck septin ring)|dip:DIP-3022N|mint:P34244 refseq:NP_012821.2|sgd:S000001584|ensemblfungi:YKL101W(gene)|ensemblfungi:YKL101W_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044879"(mitotic morphogenesis checkpoint signaling)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902935"(protein localization to septin ring)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:5G04|rcsb pdb:5KHR|rcsb pdb:5L9T|rcsb pdb:5L9U|go:"GO:0000144"(cellular bud neck septin ring)|dip:DIP-3022N|mint:P34244 psi-mi:"MI:0469"(intact) crc64:803F84F7574304CD crc64:803F84F7574304CD figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9lnAFjeIZjowGo5Vxj/3sb/bLys559292 rogid:9lnAFjeIZjowGo5Vxj/3sb/bLys559292 intact-crc:2EBEC489C7609F47|rigid:ETNfGhvvLU+os5fzYkBYwxpauVY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34761 uniprotkb:P06102 intact:EBI-20537|uniprotkb:D6W0Z0|ensemblfungi:YNL197C intact:EBI-12165|uniprotkb:D6VVP4|uniprotkb:Q6B233|ensemblfungi:YIL038C psi-mi:whi3_yeast(display_long)|uniprotkb:WHI3(gene name)|psi-mi:WHI3(display_short)|uniprotkb:N1382(orf name)|uniprotkb:YNL197C(locus name) psi-mi:not3_yeast(display_long)|uniprotkb:NOT3(gene name)|psi-mi:NOT3(display_short)|uniprotkb:YIL038C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324789|imex:IM-14275-989 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014202.1|sgd:S000005141|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|ensemblfungi:YNL197C(gene)|ensemblfungi:YNL197C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0032106"(positive regulation of response to extracellular stimulus)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0061013"(regulation of mRNA catabolic process)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071554"(cell wall organization or biogenesis)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P34761 interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR038635|interpro:IPR040168|ensemblfungi:YIL038C(gene)|ensemblfungi:YIL038C_mRNA(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|refseq:NP_012226.3|sgd:S000001300|dip:DIP-2256N|mint:P06102 psi-mi:"MI:0469"(intact) - crc64:69B76694FCC6846F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Xpn0uJiaylcupy9qYDLa0V++z6A559292 rogid:EfakZPDNU3FZeI5+rnu7YV1UsCg559292 intact-crc:8D05E67C3E30AF47|rigid:wGQfO71ig/Han00FwKa/0pveSs4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06634 uniprotkb:P34761 intact:EBI-5744|uniprotkb:D6W2R0|ensemblfungi:YOR204W intact:EBI-20537|uniprotkb:D6W0Z0|ensemblfungi:YNL197C psi-mi:ded1_yeast(display_long)|uniprotkb:DED1(gene name)|psi-mi:DED1(display_short)|uniprotkb:SPP81(gene name synonym)|uniprotkb:YOR204W(locus name)|uniprotkb:DEAD box protein 1(gene name synonym) psi-mi:whi3_yeast(display_long)|uniprotkb:WHI3(gene name)|psi-mi:WHI3(display_short)|uniprotkb:N1382(orf name)|uniprotkb:YNL197C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324800|imex:IM-14275-990 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005730|refseq:NP_014847.3|dip:DIP-5820N|mint:P06634|ensemblfungi:YOR204W(gene)|ensemblfungi:YOR204W_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763|reactome:R-SCE-6798695 refseq:NP_014202.1|sgd:S000005141|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|ensemblfungi:YNL197C(gene)|ensemblfungi:YNL197C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0032106"(positive regulation of response to extracellular stimulus)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0061013"(regulation of mRNA catabolic process)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071554"(cell wall organization or biogenesis)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P34761 psi-mi:"MI:0469"(intact) crc64:B6722D94C03BFA4B - figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FkldumX6m5gBuuaG09aTJ0kuMZM559292 rogid:Xpn0uJiaylcupy9qYDLa0V++z6A559292 intact-crc:822DB3B7BCFD460F|rigid:hdKdLA6JUaJWCnLXj2uS4nfsZvY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25339 uniprotkb:P34761 intact:EBI-23703|uniprotkb:D6VUC3|ensemblfungi:YGL014W intact:EBI-20537|uniprotkb:D6W0Z0|ensemblfungi:YNL197C psi-mi:puf4_yeast(display_long)|uniprotkb:PUF4(gene name)|psi-mi:PUF4(display_short)|uniprotkb:YGL023(orf name)|uniprotkb:YGL014W(locus name) psi-mi:whi3_yeast(display_long)|uniprotkb:WHI3(gene name)|psi-mi:WHI3(display_short)|uniprotkb:N1382(orf name)|uniprotkb:YNL197C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324811|imex:IM-14275-991 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011501.1|sgd:S000002982|dip:DIP-2638N|mint:P25339|ensemblfungi:YGL014W(gene)|ensemblfungi:YGL014W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:3BWT|rcsb pdb:3BX2|rcsb pdb:3BX3|rcsb pdb:4DZS|go:"GO:0003729"(mRNA binding) refseq:NP_014202.1|sgd:S000005141|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|ensemblfungi:YNL197C(gene)|ensemblfungi:YNL197C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0032106"(positive regulation of response to extracellular stimulus)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0061013"(regulation of mRNA catabolic process)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071554"(cell wall organization or biogenesis)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P34761 psi-mi:"MI:0469"(intact) crc64:659BA1062439F642 - figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:spjnSzTKOyi8X0oMi4wOTS+72hY559292 rogid:Xpn0uJiaylcupy9qYDLa0V++z6A559292 intact-crc:8304FB49DDB83804|rigid:cGDbH2GbxtFO2X1OvG2wSZgPzjE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34761 uniprotkb:P25655 intact:EBI-20537|uniprotkb:D6W0Z0|ensemblfungi:YNL197C intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W psi-mi:whi3_yeast(display_long)|uniprotkb:WHI3(gene name)|psi-mi:WHI3(display_short)|uniprotkb:N1382(orf name)|uniprotkb:YNL197C(locus name) psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324822|imex:IM-14275-992 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014202.1|sgd:S000005141|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|ensemblfungi:YNL197C(gene)|ensemblfungi:YNL197C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0032106"(positive regulation of response to extracellular stimulus)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0061013"(regulation of mRNA catabolic process)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071554"(cell wall organization or biogenesis)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P34761 ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 psi-mi:"MI:0469"(intact) - crc64:5B2AE15BCF95E009 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Xpn0uJiaylcupy9qYDLa0V++z6A559292 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 intact-crc:C9140D1ED80BC6D2|rigid:sKlPBiYtA1Xf3MssrBAXMItBJE4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34761 uniprotkb:P32588 intact:EBI-20537|uniprotkb:D6W0Z0|ensemblfungi:YNL197C intact:EBI-14231|ensemblfungi:YNL016W|uniprotkb:D6W1G2 psi-mi:whi3_yeast(display_long)|uniprotkb:WHI3(gene name)|psi-mi:WHI3(display_short)|uniprotkb:N1382(orf name)|uniprotkb:YNL197C(locus name) psi-mi:pub1_yeast(display_long)|uniprotkb:ARS consensus-binding protein ACBP-60(gene name synonym)|uniprotkb:Poly uridylate-binding protein(gene name synonym)|uniprotkb:PUB1(gene name)|psi-mi:PUB1(display_short)|uniprotkb:RNP1(gene name synonym)|uniprotkb:YNL016W(locus name)|uniprotkb:N2842(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324833|imex:IM-14275-993 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014202.1|sgd:S000005141|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|ensemblfungi:YNL197C(gene)|ensemblfungi:YNL197C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0032106"(positive regulation of response to extracellular stimulus)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0061013"(regulation of mRNA catabolic process)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071554"(cell wall organization or biogenesis)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P34761 refseq:NP_014382.1|sgd:S000004961|ensemblfungi:YNL016W(gene)|ensemblfungi:YNL016W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043488"(regulation of mRNA stability)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034509|interpro:IPR034639|interpro:IPR035979|rcsb pdb:2LA4|rcsb pdb:3MD1|rcsb pdb:3MD3|rcsb pdb:6Z29|mint:P32588|dip:DIP-5480N psi-mi:"MI:0469"(intact) - crc64:3B81A7735505D3CA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Xpn0uJiaylcupy9qYDLa0V++z6A559292 rogid:8xFMuEva7leVYDKg3WOmvPtRTFk559292 intact-crc:F08DDCE529F6760F|rigid:dxqrja6VYj1pRc579av51I5fqEo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34761 uniprotkb:P34761 intact:EBI-20537|uniprotkb:D6W0Z0|ensemblfungi:YNL197C intact:EBI-20537|uniprotkb:D6W0Z0|ensemblfungi:YNL197C psi-mi:whi3_yeast(display_long)|uniprotkb:WHI3(gene name)|psi-mi:WHI3(display_short)|uniprotkb:N1382(orf name)|uniprotkb:YNL197C(locus name) psi-mi:whi3_yeast(display_long)|uniprotkb:WHI3(gene name)|psi-mi:WHI3(display_short)|uniprotkb:N1382(orf name)|uniprotkb:YNL197C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324844|imex:IM-14275-994 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014202.1|sgd:S000005141|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|ensemblfungi:YNL197C(gene)|ensemblfungi:YNL197C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0032106"(positive regulation of response to extracellular stimulus)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0061013"(regulation of mRNA catabolic process)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071554"(cell wall organization or biogenesis)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P34761 refseq:NP_014202.1|sgd:S000005141|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|ensemblfungi:YNL197C(gene)|ensemblfungi:YNL197C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0032106"(positive regulation of response to extracellular stimulus)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0061013"(regulation of mRNA catabolic process)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071554"(cell wall organization or biogenesis)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P34761 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Xpn0uJiaylcupy9qYDLa0V++z6A559292 rogid:Xpn0uJiaylcupy9qYDLa0V++z6A559292 intact-crc:81DA87BA5F43A03C|rigid:F8XpfH7zOkrMD3MOKXIQ22bQnWw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34909 uniprotkb:P34761 intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W intact:EBI-20537|uniprotkb:D6W0Z0|ensemblfungi:YNL197C psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:whi3_yeast(display_long)|uniprotkb:WHI3(gene name)|psi-mi:WHI3(display_short)|uniprotkb:N1382(orf name)|uniprotkb:YNL197C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324855|imex:IM-14275-995 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 refseq:NP_014202.1|sgd:S000005141|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|ensemblfungi:YNL197C(gene)|ensemblfungi:YNL197C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0032106"(positive regulation of response to extracellular stimulus)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0061013"(regulation of mRNA catabolic process)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071554"(cell wall organization or biogenesis)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P34761 psi-mi:"MI:0469"(intact) crc64:8847084BD9BF48B7 - figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 rogid:Xpn0uJiaylcupy9qYDLa0V++z6A559292 intact-crc:D2B900FFC66898C5|rigid:pVsB6/F8mPgImQJGdaD0VVicC4Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35732 uniprotkb:P34761 intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C intact:EBI-20537|uniprotkb:D6W0Z0|ensemblfungi:YNL197C psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:whi3_yeast(display_long)|uniprotkb:WHI3(gene name)|psi-mi:WHI3(display_short)|uniprotkb:N1382(orf name)|uniprotkb:YNL197C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324866|imex:IM-14275-996 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 refseq:NP_014202.1|sgd:S000005141|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|ensemblfungi:YNL197C(gene)|ensemblfungi:YNL197C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0032106"(positive regulation of response to extracellular stimulus)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0061013"(regulation of mRNA catabolic process)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071554"(cell wall organization or biogenesis)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P34761 psi-mi:"MI:0469"(intact) crc64:05734E2D0B7389AC - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 rogid:Xpn0uJiaylcupy9qYDLa0V++z6A559292 intact-crc:0A8F96A836E641C3|rigid:OHdnPdGcyPDxTXsCFNvJIhTu5Q0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39008 uniprotkb:P34761 intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C intact:EBI-20537|uniprotkb:D6W0Z0|ensemblfungi:YNL197C psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:whi3_yeast(display_long)|uniprotkb:WHI3(gene name)|psi-mi:WHI3(display_short)|uniprotkb:N1382(orf name)|uniprotkb:YNL197C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324877|imex:IM-14275-997 author score:88.11 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N refseq:NP_014202.1|sgd:S000005141|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|ensemblfungi:YNL197C(gene)|ensemblfungi:YNL197C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0032106"(positive regulation of response to extracellular stimulus)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0061013"(regulation of mRNA catabolic process)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071554"(cell wall organization or biogenesis)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P34761 psi-mi:"MI:0469"(intact) crc64:F3CAF97106A65933 - figure legend:tables S3 and S4|author-confidence:88.11|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 rogid:Xpn0uJiaylcupy9qYDLa0V++z6A559292 intact-crc:7465F2D424F4F35A|rigid:vR+dc3/fCBHPx+cw66AVEcDyATM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34761 uniprotkb:P40070 intact:EBI-20537|uniprotkb:D6W0Z0|ensemblfungi:YNL197C intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W psi-mi:whi3_yeast(display_long)|uniprotkb:WHI3(gene name)|psi-mi:WHI3(display_short)|uniprotkb:N1382(orf name)|uniprotkb:YNL197C(locus name) psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324888|imex:IM-14275-998 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014202.1|sgd:S000005141|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|ensemblfungi:YNL197C(gene)|ensemblfungi:YNL197C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0032106"(positive regulation of response to extracellular stimulus)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0061013"(regulation of mRNA catabolic process)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071554"(cell wall organization or biogenesis)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P34761 sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) - crc64:69CAC1F01D5BFA98 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Xpn0uJiaylcupy9qYDLa0V++z6A559292 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 intact-crc:98F9D27017635A9E|rigid:3iruNXViaFuih04WR0ao1Ekzgv0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34761 uniprotkb:P45978 intact:EBI-20537|uniprotkb:D6W0Z0|ensemblfungi:YNL197C intact:EBI-16691|ensemblfungi:YPR129W|uniprotkb:D6W4C6 psi-mi:whi3_yeast(display_long)|uniprotkb:WHI3(gene name)|psi-mi:WHI3(display_short)|uniprotkb:N1382(orf name)|uniprotkb:YNL197C(locus name) psi-mi:scd6_yeast(display_long)|uniprotkb:P9659.10(orf name)|uniprotkb:YPR129W(locus name)|uniprotkb:SCD6(gene name)|psi-mi:SCD6(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324899|imex:IM-14275-999 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014202.1|sgd:S000005141|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|ensemblfungi:YNL197C(gene)|ensemblfungi:YNL197C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0032106"(positive regulation of response to extracellular stimulus)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0061013"(regulation of mRNA catabolic process)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071554"(cell wall organization or biogenesis)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P34761 ensemblfungi:YPR129W(gene)|ensemblfungi:YPR129W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:0003729"(mRNA binding)|interpro:IPR025609|refseq:NP_015454.1|sgd:S000006333|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR019050|interpro:IPR025761|interpro:IPR025762|interpro:IPR025768|mint:P45978 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Xpn0uJiaylcupy9qYDLa0V++z6A559292 rogid:QRNg1nbLjsxR5twooPvrSPZTWO0559292 intact-crc:A1AF490136411CDD|rigid:MGAYeJhRHQRQch/f21R00M5pAgw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53829 uniprotkb:P34761 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-20537|uniprotkb:D6W0Z0|ensemblfungi:YNL197C psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:whi3_yeast(display_long)|uniprotkb:WHI3(gene name)|psi-mi:WHI3(display_short)|uniprotkb:N1382(orf name)|uniprotkb:YNL197C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324910|imex:IM-14275-1000 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 refseq:NP_014202.1|sgd:S000005141|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|ensemblfungi:YNL197C(gene)|ensemblfungi:YNL197C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0032106"(positive regulation of response to extracellular stimulus)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0061013"(regulation of mRNA catabolic process)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071554"(cell wall organization or biogenesis)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P34761 psi-mi:"MI:0469"(intact) crc64:F3DBABE6AD3C7F3C - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:Xpn0uJiaylcupy9qYDLa0V++z6A559292 intact-crc:550D6C396E129DA0|rigid:cybezRKicy6SXp3Tl6OLMgX4m1A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06100 uniprotkb:P34909 intact:EBI-12153|uniprotkb:D6VRI6|ensemblfungi:YDL165W intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W psi-mi:not2_yeast(display_long)|uniprotkb:CDC36(gene name)|psi-mi:CDC36(display_short)|uniprotkb:DNA19(gene name synonym)|uniprotkb:NOT2(gene name synonym)|uniprotkb:YDL165W(locus name)|uniprotkb:cell division cycle protein 36(gene name synonym) psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324921|imex:IM-14275-1001 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDL165W(gene)|ensemblfungi:YDL165W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|refseq:NP_010116.1|sgd:S000002324|dip:DIP-590N|mint:P06100 ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 psi-mi:"MI:0469"(intact) crc64:7D0B69657F791371 crc64:8847084BD9BF48B7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:bOgpnRcqWbxkhHJg140qzPxIBJQ559292 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 intact-crc:DC611520DC58A73A|rigid:JXfMD3TC8vGlh/nXKH+Sk9jskmI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06102 uniprotkb:P34909 intact:EBI-12165|uniprotkb:D6VVP4|uniprotkb:Q6B233|ensemblfungi:YIL038C intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W psi-mi:not3_yeast(display_long)|uniprotkb:NOT3(gene name)|psi-mi:NOT3(display_short)|uniprotkb:YIL038C(locus name) psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324932|imex:IM-14275-1002 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR038635|interpro:IPR040168|ensemblfungi:YIL038C(gene)|ensemblfungi:YIL038C_mRNA(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|refseq:NP_012226.3|sgd:S000001300|dip:DIP-2256N|mint:P06102 ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 psi-mi:"MI:0469"(intact) crc64:69B76694FCC6846F crc64:8847084BD9BF48B7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:EfakZPDNU3FZeI5+rnu7YV1UsCg559292 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 intact-crc:DE611529A6AB97BE|rigid:9kIM2kUroCqsxrCWxJf6PwNNrxE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25644 uniprotkb:P34909 intact:EBI-204|uniprotkb:Q8NKJ3|uniprotkb:D6VR80|ensemblfungi:YCR077C intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W psi-mi:pat1_yeast(display_long)|uniprotkb:PAT1(gene name)|psi-mi:PAT1(display_short)|uniprotkb:Decapping activator and translational repressor PAT1(gene name synonym)|uniprotkb:mRNA turnover protein 1(gene name synonym)|uniprotkb:MRT1(gene name synonym)|uniprotkb:Topoisomerase II-associated protein PAT1(gene name synonym)|uniprotkb:YCR77C(orf name)|uniprotkb:YCR077C(locus name) psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324943|imex:IM-14275-1003 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010002.3|sgd:S000000673|mint:P25644|dip:DIP-883N|ensemblfungi:YCR077C(gene)|ensemblfungi:YCR077C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000776"(kinetochore)|go:"GO:0000932"(P-body)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033962"(P-body assembly)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0051301"(cell division)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR019167|interpro:IPR039900|rcsb pdb:4BRW|rcsb pdb:4C8Q|rcsb pdb:4N0A|rcsb pdb:4OGP|rcsb pdb:4OJJ|rcsb pdb:5LM5|rcsb pdb:5LMF|rcsb pdb:5LMG|reactome:R-SCE-430039 ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 psi-mi:"MI:0469"(intact) crc64:2DBE1210C173E468 crc64:8847084BD9BF48B7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kov8R0RAgIOPffQ7ydjCUxjoE/M559292 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 intact-crc:F411FE4FF9541FF1|rigid:Nl2LiLmpk9ErJW/V2rwpGWPc+9E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25655 uniprotkb:P34909 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324954|imex:IM-14275-1004 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 psi-mi:"MI:0469"(intact) crc64:5B2AE15BCF95E009 crc64:8847084BD9BF48B7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 intact-crc:9A70FE4B4090FE2B|rigid:IiuM2qWmT0VyMAABn9jmgrhKARk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34761 uniprotkb:P34909 intact:EBI-20537|uniprotkb:D6W0Z0|ensemblfungi:YNL197C intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W psi-mi:whi3_yeast(display_long)|uniprotkb:WHI3(gene name)|psi-mi:WHI3(display_short)|uniprotkb:N1382(orf name)|uniprotkb:YNL197C(locus name) psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324965|imex:IM-14275-1005 author score:98.18 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014202.1|sgd:S000005141|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|ensemblfungi:YNL197C(gene)|ensemblfungi:YNL197C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0032106"(positive regulation of response to extracellular stimulus)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0061013"(regulation of mRNA catabolic process)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071554"(cell wall organization or biogenesis)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P34761 ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 psi-mi:"MI:0469"(intact) - crc64:8847084BD9BF48B7 figure legend:tables S3 and S4|author-confidence:98.18|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Xpn0uJiaylcupy9qYDLa0V++z6A559292 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 intact-crc:53720F67D805AC4B|rigid:pVsB6/F8mPgImQJGdaD0VVicC4Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35732 uniprotkb:P34909 intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324976|imex:IM-14275-1006 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 psi-mi:"MI:0469"(intact) crc64:05734E2D0B7389AC crc64:8847084BD9BF48B7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 intact-crc:10D1D88DC69BF25B|rigid:OERlUgdZAnTWZLVY3wlXMpOjZCE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34909 uniprotkb:P39008 intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324987|imex:IM-14275-1007 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N psi-mi:"MI:0469"(intact) crc64:8847084BD9BF48B7 crc64:F3CAF97106A65933 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 intact-crc:6E3A0D41D538F0C2|rigid:ToyRSMSjkf1SvrGd9BKHypBDGP4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39517 uniprotkb:P34909 intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6324998|imex:IM-14275-1008 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 psi-mi:"MI:0469"(intact) crc64:062CFA56DF6F2CEE crc64:8847084BD9BF48B7 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 intact-crc:7E96FF0402CCDFB0|rigid:MQ6uqYWS97griFduu/vl1FKgpRQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34909 uniprotkb:P47135 intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W intact:EBI-9422|ensemblfungi:YJR091C|uniprotkb:D6VWQ9 psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:jsn1_yeast(display_long)|uniprotkb:JSN1(gene name)|psi-mi:JSN1(display_short)|uniprotkb:PUF1(gene name synonym)|uniprotkb:YJR091C(locus name)|uniprotkb:J1890(orf name)|uniprotkb:Pumilio homology domain family member 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325009|imex:IM-14275-1009 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 refseq:NP_012624.1|sgd:S000003851|ensemblfungi:YJR091C(gene)|ensemblfungi:YJR091C_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0032473"(cytoplasmic side of mitochondrial outer membrane)|go:"GO:0034629"|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR035979|mint:P47135|dip:DIP-1281N psi-mi:"MI:0469"(intact) crc64:8847084BD9BF48B7 - figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 rogid:K81+s0mfKupe09bngR/jb7cGTQE559292 intact-crc:07EEC430E9BBC875|rigid:EaG/q180UVo8jPUyFLp/vKvun5g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34909 uniprotkb:P53829 intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325020|imex:IM-14275-1010 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 psi-mi:"MI:0469"(intact) crc64:8847084BD9BF48B7 crc64:F3DBABE6AD3C7F3C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 intact-crc:4F53221C9E6F2E38|rigid:8cVnmhmeEe1Ac03UONcz0T2ajoA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53935 uniprotkb:P34909 intact:EBI-28788|uniprotkb:Q45TZ3|uniprotkb:D6W189|ensemblfungi:YNL091W intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W psi-mi:nst1_yeast(display_long)|uniprotkb:YNL091W(locus name)|uniprotkb:N2231(orf name)|uniprotkb:NST1(gene name)|psi-mi:NST1(display_short)|uniprotkb:Negatively-affecting salt tolerance protein 1(gene name synonym) psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325031|imex:IM-14275-1011 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014308.1|sgd:S000005035|dip:DIP-872N|mint:P53935|ensemblfungi:YNL091W(gene)|ensemblfungi:YNL091W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009651"(response to salt stress)|interpro:IPR025279 ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 psi-mi:"MI:0469"(intact) - crc64:8847084BD9BF48B7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WOSVMqWhtYPlZyt+vfdkpJAHHBg559292 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 intact-crc:0271B1070B1F7466|rigid:zhdrJ/EhUzG5UHl+DJzZykKMZuE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34909 uniprotkb:P57743 intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W intact:EBI-10227|uniprotkb:Q05176|uniprotkb:Q06759|uniprotkb:D6VZ73|ensemblfungi:YLR438C-A psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:lsm3_yeast(display_long)|uniprotkb:LSM3(gene name)|psi-mi:LSM3(display_short)|uniprotkb:SMX4(gene name synonym)|uniprotkb:USS2(gene name synonym)|uniprotkb:YLR438C-A(locus name)|uniprotkb:SmX4 protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325042|imex:IM-14275-1012 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 sgd:S000006434|ensemblfungi:YLR438C-A(gene)|ensemblfungi:YLR438C-A_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034105|interpro:IPR040002|rcsb pdb:3BW1|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:4N0A|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039|rcsb pdb:4M75|refseq:NP_013543.3|dip:DIP-2587N|mint:P57743 psi-mi:"MI:0469"(intact) crc64:8847084BD9BF48B7 crc64:787084EF6A5945B7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 rogid:nYl7At1SnlSwN+nWr1F1xm0tdDE559292 intact-crc:42E9DDC2A216170B|rigid:H4AvRbntM1/9BDbxAQtA84DtgxQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34909 uniprotkb:Q12514 intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W intact:EBI-12184|uniprotkb:D6W476|ensemblfungi:YPR072W psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:not5_yeast(display_long)|uniprotkb:NOT5(gene name)|psi-mi:NOT5(display_short)|uniprotkb:YP9499.27(orf name)|uniprotkb:YPR072W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325053|imex:IM-14275-1013 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 ensemblfungi:YPR072W(gene)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|rcsb pdb:6TB3|ensemblfungi:YPR072W_mRNA(transcript)|refseq:NP_015397.1|sgd:S000006276|dip:DIP-2257N|mint:Q12514 psi-mi:"MI:0469"(intact) crc64:8847084BD9BF48B7 crc64:073137119B3E92BC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 rogid:+XON8Ps4xCFhw058U9d2voUy2dc559292 intact-crc:C32808BE81B9C94B|rigid:h70FSQhtn+Ex4dJzG8HMVjd1i3k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12028 uniprotkb:P35181 intact:EBI-33025|uniprotkb:D6W439|ensemblfungi:YPR029C intact:EBI-2612|uniprotkb:D6VYH5|ensemblfungi:YLR170C psi-mi:ap1g1_yeast(display_long)|uniprotkb:APL4(gene name)|psi-mi:APL4(display_short)|uniprotkb:Clathrin assembly protein complex 1 gamma large chain(gene name synonym)|uniprotkb:Clathrin assembly protein large gamma chain(gene name synonym)|uniprotkb:Gamma-adaptin(gene name synonym)|uniprotkb:YPR029C(locus name) psi-mi:ap1s1_yeast(display_long)|uniprotkb:APS1(gene name)|psi-mi:APS1(display_short)|uniprotkb:YAP19(gene name synonym)|uniprotkb:YLR170C(locus name)|uniprotkb:L9470.16(orf name)|uniprotkb:Sigma1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor AP-1 19 kDa adaptin(gene name synonym)|uniprotkb:HA1 19 kDa subunit(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP19(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP19(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 sigma-1 small chain(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325064|imex:IM-14275-1014 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015354.1|sgd:S000006233|mint:Q12028|dip:DIP-3913N|ensemblfungi:YPR029C(gene)|ensemblfungi:YPR029C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030121"(AP-1 adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017107(Adaptor protein complex AP-1, gamma subunit)|reactome:R-SCE-432720 refseq:NP_013271.1|sgd:S000004160|dip:DIP-4806N|mint:P35181|ensemblfungi:YLR170C(gene)|ensemblfungi:YLR170C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030121"(AP-1 adaptor complex)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000804(Clathrin adaptor, sigma subunit/coatomer, zeta subunit)|interpro:IPR011012(Longin-like)|interpro:IPR016635(Adaptor protein complex, sigma subunit)|interpro:IPR022775|interpro:IPR044733|reactome:R-SCE-432720 psi-mi:"MI:0469"(intact) crc64:ABB619E9DC4F565C crc64:1A584883F1DF815D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nzjklmQlRHNY/Wqmrg6GbLG17e8559292 rogid:MSl/Rj/unUQm0HSBgFC1jyYJpBM559292 intact-crc:C87D7013BA180DDB|rigid:BGCGpIuY1i3ivUdULshZXcW4kI0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12163 uniprotkb:P35182 intact:EBI-34713|uniprotkb:D6VSE2|ensemblfungi:YDR162C intact:EBI-12784|uniprotkb:D6VRY2|ensemblfungi:YDL006W psi-mi:nbp2_yeast(display_long)|uniprotkb:NBP2(gene name)|psi-mi:NBP2(display_short)|uniprotkb:YDR162C(locus name) psi-mi:pp2c1_yeast(display_long)|uniprotkb:PTC1(gene name)|psi-mi:PTC1(display_short)|uniprotkb:TPD1(gene name synonym)|uniprotkb:YDL006W(locus name)|uniprotkb:D2925(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325075|imex:IM-14275-1015 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002569|refseq:NP_010446.3|mint:Q12163|dip:DIP-1538N|ensemblfungi:YDR162C(gene)|ensemblfungi:YDR162C_mRNA(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|rcsb pdb:1YN8|rcsb pdb:2LCS interpro:IPR000222(Protein phosphatase 2C, manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|ensemblfungi:YDL006W(gene)|ensemblfungi:YDL006W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0051389"(obsolete inactivation of MAPKK activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1990439"(MAP kinase serine/threonine phosphatase activity)|refseq:NP_010278.3|sgd:S000002164|mint:P35182|dip:DIP-1537N psi-mi:"MI:0469"(intact) crc64:A7458854D5000EA6 crc64:FA384D2541B20D50 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rxEwkyNpxLvCh9usNVTOPCYedkU559292 rogid:iWNdaik/M9S814zgZEQNyOktcX8559292 intact-crc:3C518FD0AF9D41CA|rigid:cVq6gfr90qWYdU5puReoLe+20Zg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35184 uniprotkb:Q3E767 intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W intact:EBI-2091938|uniprotkb:D6W1B2|ensemblfungi:YNL067W-B psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short) psi-mi:yn67b_yeast(display_long)|uniprotkb:YNL067W-A(orf name)|uniprotkb:YNL067W-B(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325086|imex:IM-14275-1016 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184 sgd:S000028810|refseq:NP_878156.3|mint:Q3E767|ensemblfungi:YNL067W-B(gene)|ensemblfungi:YNL067W-B_mRNA(transcript) psi-mi:"MI:0469"(intact) crc64:981D566076B0C881 - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292 rogid:ji2S6Wl/db2Il8qODrcYLVx6uEE559292 intact-crc:8E9D6B8CCFB5BABB|rigid:hSaaChiLfriM5tXGqetNGybCiqE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35189 uniprotkb:P11747 intact:EBI-18920|uniprotkb:Q02460|uniprotkb:D6W3N8|ensemblfungi:YPL129W intact:EBI-18897|uniprotkb:D6W0I7|ensemblfungi:YML098W psi-mi:taf14_yeast(display_long)|uniprotkb:ANC1(gene name synonym)|uniprotkb:CST10(gene name synonym)|uniprotkb:YPL129W(locus name)|uniprotkb:TAF14(gene name)|psi-mi:TAF14(display_short)|uniprotkb:SWP29(gene name synonym)|uniprotkb:TAF30(gene name synonym)|uniprotkb:TFG3(gene name synonym)|uniprotkb:TBP-associated factor 14(gene name synonym)|uniprotkb:TBP-associated factor 30 kDa(gene name synonym)|uniprotkb:Transcription initiation factor TFIIF 30 kDa subunit(gene name synonym)|uniprotkb:Transcription factor G 30 kDa subunit(gene name synonym)|uniprotkb:SWI/SNF chromatin-remodeling complex subunit TAF14(gene name synonym)|uniprotkb:SWI/SNF complex subunit TAF14(gene name synonym)|uniprotkb:SWI/SNF complex 29 kDa subunit(gene name synonym)|uniprotkb:Actin non-complementing mutant 1(gene name synonym)|uniprotkb:Chromosome stability protein 10(gene name synonym) psi-mi:taf13_yeast(display_long)|uniprotkb:TAF13(gene name)|psi-mi:TAF13(display_short)|uniprotkb:FUN81(gene name synonym)|uniprotkb:TAF19(gene name synonym)|uniprotkb:YML098W(locus name)|uniprotkb:TBP-associated factor 13(gene name synonym)|uniprotkb:TBP-associated factor 19 kDa(gene name synonym)|uniprotkb:TAFII-19(gene name synonym)|uniprotkb:Function unknown 81 protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325097|imex:IM-14275-1017 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015196.1|sgd:S000006050|ensemblfungi:YPL129W(gene)|ensemblfungi:YPL129W_mRNA(transcript)|go:"GO:0001111"(promoter clearance from RNA polymerase II promoter)|go:"GO:0001174"(transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005674"(transcription factor TFIIF complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0016592"(mediator complex)|go:"GO:0031011"(Ino80 complex)|go:"GO:0033100"(NuA3 histone acetyltransferase complex)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:1990467"(NuA3a histone acetyltransferase complex)|go:"GO:1990468"(NuA3b histone acetyltransferase complex)|interpro:IPR005033(YEATS)|interpro:IPR016665(SAS complex, SAS5 subunit/transcription initiation factor IID, subunit 14)|interpro:IPR027353|interpro:IPR038704|rcsb pdb:2L7E|rcsb pdb:3QRL|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5SVA|rcsb pdb:6LQZ|rcsb pdb:6MIN|rcsb pdb:6MIO|rcsb pdb:6MIP|rcsb pdb:6MIQ|reactome:R-SCE-674695|reactome:R-SCE-75955|dip:DIP-1147N|mint:P35189 refseq:NP_013611.1|sgd:S000004564|ensemblfungi:YML098W(gene)|ensemblfungi:YML098W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|interpro:IPR003195(Transcription initiation factor IID, 18 kDa subunit)|interpro:IPR009072(Histone-fold)|reactome:R-SCE-674695|reactome:R-SCE-6807505|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-76042|dip:DIP-2054N|mint:P11747 psi-mi:"MI:0469"(intact) crc64:60EA5EC2474B1B9C - figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vlV/9gdZlSdSF2uKWJM76rcCWUg559292 rogid:N+MUCqLYlBQa1L2NcpyY5ImMIYM559292 intact-crc:E109924944EFB3C3|rigid:4C6TqaSrH33VZ3/+NeiW90KUy1E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20434 uniprotkb:P35189 intact:EBI-15781|uniprotkb:Q02121|ensemblfungi:YBR154C|uniprotkb:D6VQE9 intact:EBI-18920|uniprotkb:Q02460|uniprotkb:D6W3N8|ensemblfungi:YPL129W psi-mi:rpab1_yeast(display_long)|uniprotkb:RPB5(gene name)|psi-mi:RPB5(display_short)|uniprotkb:YBR154C(locus name)|uniprotkb:YBR1204(orf name)|uniprotkb:RPA7(gene name synonym)|uniprotkb:RPC9(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide(gene name synonym)|uniprotkb:ABC27(gene name synonym) psi-mi:taf14_yeast(display_long)|uniprotkb:ANC1(gene name synonym)|uniprotkb:CST10(gene name synonym)|uniprotkb:YPL129W(locus name)|uniprotkb:TAF14(gene name)|psi-mi:TAF14(display_short)|uniprotkb:SWP29(gene name synonym)|uniprotkb:TAF30(gene name synonym)|uniprotkb:TFG3(gene name synonym)|uniprotkb:TBP-associated factor 14(gene name synonym)|uniprotkb:TBP-associated factor 30 kDa(gene name synonym)|uniprotkb:Transcription initiation factor TFIIF 30 kDa subunit(gene name synonym)|uniprotkb:Transcription factor G 30 kDa subunit(gene name synonym)|uniprotkb:SWI/SNF chromatin-remodeling complex subunit TAF14(gene name synonym)|uniprotkb:SWI/SNF complex subunit TAF14(gene name synonym)|uniprotkb:SWI/SNF complex 29 kDa subunit(gene name synonym)|uniprotkb:Actin non-complementing mutant 1(gene name synonym)|uniprotkb:Chromosome stability protein 10(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325108|imex:IM-14275-1018 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|rcsb pdb:1WCM|rcsb pdb:1Y1V|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|rcsb pdb:2B63|rcsb pdb:2B8K|interpro:IPR020608|interpro:IPR020609|rcsb pdb:2E2H|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:1DZF|rcsb pdb:1I3Q|rcsb pdb:2E2I|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:5M5Y|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6H67|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:2E2J|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|ensemblfungi:YBR154C(gene)|ensemblfungi:YBR154C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4V1M|rcsb pdb:2JA5|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2JA6|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:2JA7|rcsb pdb:3GTG|rcsb pdb:2JA8|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:2NVQ|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4YM7|rcsb pdb:5C3E|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5G5L|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6H68|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|rcsb pdb:6UQ2|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-77075|reactome:R-SCE-9018519|refseq:NP_009712.1|sgd:S000000358|dip:DIP-71N|mint:P20434 refseq:NP_015196.1|sgd:S000006050|ensemblfungi:YPL129W(gene)|ensemblfungi:YPL129W_mRNA(transcript)|go:"GO:0001111"(promoter clearance from RNA polymerase II promoter)|go:"GO:0001174"(transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005674"(transcription factor TFIIF complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0016592"(mediator complex)|go:"GO:0031011"(Ino80 complex)|go:"GO:0033100"(NuA3 histone acetyltransferase complex)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:1990467"(NuA3a histone acetyltransferase complex)|go:"GO:1990468"(NuA3b histone acetyltransferase complex)|interpro:IPR005033(YEATS)|interpro:IPR016665(SAS complex, SAS5 subunit/transcription initiation factor IID, subunit 14)|interpro:IPR027353|interpro:IPR038704|rcsb pdb:2L7E|rcsb pdb:3QRL|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5SVA|rcsb pdb:6LQZ|rcsb pdb:6MIN|rcsb pdb:6MIO|rcsb pdb:6MIP|rcsb pdb:6MIQ|reactome:R-SCE-674695|reactome:R-SCE-75955|dip:DIP-1147N|mint:P35189 psi-mi:"MI:0469"(intact) crc64:2A15F7114D69D829 crc64:60EA5EC2474B1B9C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:j/jAJ2fXWf4ebK1aWTWrKERGUpM559292 rogid:vlV/9gdZlSdSF2uKWJM76rcCWUg559292 intact-crc:40250A64377AB4F6|rigid:VVkRUizuShMk83qp1CPb1LRoV8g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23724 uniprotkb:P35189 intact:EBI-13984|ensemblfungi:YBL041W|uniprotkb:D6VPV7 intact:EBI-18920|uniprotkb:Q02460|uniprotkb:D6W3N8|ensemblfungi:YPL129W psi-mi:psb6_yeast(display_long)|uniprotkb:PRE7(gene name)|psi-mi:PRE7(display_short)|uniprotkb:PRS3(gene name synonym)|uniprotkb:PTS1(gene name synonym)|uniprotkb:YBL0407(orf name)|uniprotkb:YBL041W(locus name)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym) psi-mi:taf14_yeast(display_long)|uniprotkb:ANC1(gene name synonym)|uniprotkb:CST10(gene name synonym)|uniprotkb:YPL129W(locus name)|uniprotkb:TAF14(gene name)|psi-mi:TAF14(display_short)|uniprotkb:SWP29(gene name synonym)|uniprotkb:TAF30(gene name synonym)|uniprotkb:TFG3(gene name synonym)|uniprotkb:TBP-associated factor 14(gene name synonym)|uniprotkb:TBP-associated factor 30 kDa(gene name synonym)|uniprotkb:Transcription initiation factor TFIIF 30 kDa subunit(gene name synonym)|uniprotkb:Transcription factor G 30 kDa subunit(gene name synonym)|uniprotkb:SWI/SNF chromatin-remodeling complex subunit TAF14(gene name synonym)|uniprotkb:SWI/SNF complex subunit TAF14(gene name synonym)|uniprotkb:SWI/SNF complex 29 kDa subunit(gene name synonym)|uniprotkb:Actin non-complementing mutant 1(gene name synonym)|uniprotkb:Chromosome stability protein 10(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325119|imex:IM-14275-1019 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|ensemblfungi:YBL041W(gene)|rcsb pdb:3JCP|ensemblfungi:YBL041W_mRNA(transcript)|rcsb pdb:3MG0|go:"GO:0004175"(endopeptidase activity)|rcsb pdb:3MG4|go:"GO:0004298"(threonine-type endopeptidase activity)|rcsb pdb:3MG6|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|rcsb pdb:3MG7|rcsb pdb:3MG8|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:5L68|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HTB|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-69601|refseq:NP_009512.1|sgd:S000000137|mint:P23724|dip:DIP-2821N refseq:NP_015196.1|sgd:S000006050|ensemblfungi:YPL129W(gene)|ensemblfungi:YPL129W_mRNA(transcript)|go:"GO:0001111"(promoter clearance from RNA polymerase II promoter)|go:"GO:0001174"(transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005674"(transcription factor TFIIF complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0016592"(mediator complex)|go:"GO:0031011"(Ino80 complex)|go:"GO:0033100"(NuA3 histone acetyltransferase complex)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:1990467"(NuA3a histone acetyltransferase complex)|go:"GO:1990468"(NuA3b histone acetyltransferase complex)|interpro:IPR005033(YEATS)|interpro:IPR016665(SAS complex, SAS5 subunit/transcription initiation factor IID, subunit 14)|interpro:IPR027353|interpro:IPR038704|rcsb pdb:2L7E|rcsb pdb:3QRL|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5SVA|rcsb pdb:6LQZ|rcsb pdb:6MIN|rcsb pdb:6MIO|rcsb pdb:6MIP|rcsb pdb:6MIQ|reactome:R-SCE-674695|reactome:R-SCE-75955|dip:DIP-1147N|mint:P35189 psi-mi:"MI:0469"(intact) crc64:770A4DF1DF0A0F0E crc64:60EA5EC2474B1B9C figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WzmtcPCO24lWABFyM7pXZaI9wj0559292 rogid:vlV/9gdZlSdSF2uKWJM76rcCWUg559292 intact-crc:1A728D67327A0723|rigid:9rE8z7MVwn29pkqkkAPJYfsCMZM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35189 uniprotkb:P38323 intact:EBI-18920|uniprotkb:Q02460|uniprotkb:D6W3N8|ensemblfungi:YPL129W intact:EBI-10575|ensemblfungi:YBR227C|uniprotkb:D6VQM2 psi-mi:taf14_yeast(display_long)|uniprotkb:ANC1(gene name synonym)|uniprotkb:CST10(gene name synonym)|uniprotkb:YPL129W(locus name)|uniprotkb:TAF14(gene name)|psi-mi:TAF14(display_short)|uniprotkb:SWP29(gene name synonym)|uniprotkb:TAF30(gene name synonym)|uniprotkb:TFG3(gene name synonym)|uniprotkb:TBP-associated factor 14(gene name synonym)|uniprotkb:TBP-associated factor 30 kDa(gene name synonym)|uniprotkb:Transcription initiation factor TFIIF 30 kDa subunit(gene name synonym)|uniprotkb:Transcription factor G 30 kDa subunit(gene name synonym)|uniprotkb:SWI/SNF chromatin-remodeling complex subunit TAF14(gene name synonym)|uniprotkb:SWI/SNF complex subunit TAF14(gene name synonym)|uniprotkb:SWI/SNF complex 29 kDa subunit(gene name synonym)|uniprotkb:Actin non-complementing mutant 1(gene name synonym)|uniprotkb:Chromosome stability protein 10(gene name synonym) psi-mi:clpx_yeast(display_long)|uniprotkb:MCX1(gene name)|psi-mi:MCX1(display_short)|uniprotkb:ATP-dependent unfoldase ClpX(gene name synonym)|uniprotkb:YBR1524(orf name)|uniprotkb:YBR227C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325130|imex:IM-14275-1020 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015196.1|sgd:S000006050|ensemblfungi:YPL129W(gene)|ensemblfungi:YPL129W_mRNA(transcript)|go:"GO:0001111"(promoter clearance from RNA polymerase II promoter)|go:"GO:0001174"(transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005674"(transcription factor TFIIF complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0016592"(mediator complex)|go:"GO:0031011"(Ino80 complex)|go:"GO:0033100"(NuA3 histone acetyltransferase complex)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:1990467"(NuA3a histone acetyltransferase complex)|go:"GO:1990468"(NuA3b histone acetyltransferase complex)|interpro:IPR005033(YEATS)|interpro:IPR016665(SAS complex, SAS5 subunit/transcription initiation factor IID, subunit 14)|interpro:IPR027353|interpro:IPR038704|rcsb pdb:2L7E|rcsb pdb:3QRL|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5SVA|rcsb pdb:6LQZ|rcsb pdb:6MIN|rcsb pdb:6MIO|rcsb pdb:6MIP|rcsb pdb:6MIQ|reactome:R-SCE-674695|reactome:R-SCE-75955|dip:DIP-1147N|mint:P35189 ensemblfungi:YBR227C(gene)|ensemblfungi:YBR227C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006508"(proteolysis)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030163"(protein catabolic process)|go:"GO:0042026"(protein refolding)|go:"GO:1904287"(positive regulation of protein-pyridoxal-5-phosphate linkage)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR027417|refseq:NP_009786.1|sgd:S000000431|mint:P38323|dip:DIP-6422N psi-mi:"MI:0469"(intact) crc64:60EA5EC2474B1B9C crc64:A054D1618CD50A26 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vlV/9gdZlSdSF2uKWJM76rcCWUg559292 rogid:1gRZ7BHrcq+9pbjgJ6S+IxPD/kM559292 intact-crc:8E476DF9596263AE|rigid:NBZg1xTgLXKY1rcIJxFREOHOExQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35206 uniprotkb:Q02774 intact:EBI-2051140|uniprotkb:D6VQ36|ensemblfungi:YBR036C intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 psi-mi:csg2_yeast(display_long)|uniprotkb:CLS2(gene name synonym)|uniprotkb:YBR0404(orf name)|uniprotkb:YBR036C(locus name)|uniprotkb:CSG2(gene name)|psi-mi:CSG2(display_short) psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325141|imex:IM-14275-1021 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000240|refseq:NP_009592.1|dip:DIP-8095N|mint:P35206|ensemblfungi:YBR036C(gene)|ensemblfungi:YBR036C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006688"(glycosphingolipid biosynthetic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030234"(enzyme regulator activity)|interpro:IPR018247|interpro:IPR031581 refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:EHDjwiK1XOXY3MEZ03X2l1fu/MQ559292 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 intact-crc:8D10DAFCC5189365|rigid:OLYXeY4+v3Jte6Yp3fD7eIbWh7Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32445 uniprotkb:P35718 intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A intact:EBI-15854|uniprotkb:D6VX52|ensemblfungi:YKL144C psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:rpc8_yeast(display_long)|uniprotkb:RPC25(gene name)|psi-mi:RPC25(display_short)|uniprotkb:YKL144C(locus name)|uniprotkb:YKL1(orf name)|uniprotkb:UNF1(orf name)|uniprotkb:RNA polymerase III subunit C25(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III 25 kDa polypeptide(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325163|imex:IM-14275-1023 author score:99.34 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 refseq:NP_012778.1|sgd:S000001627|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|ensemblfungi:YKL144C_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR004519(DNA-directed RNA polymerase)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013238(RNA polymerase III, subunit Rpc25)|interpro:IPR036898|rcsb pdb:2CKZ|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|ensemblfungi:YKL144C(gene)|dip:DIP-1414N|mint:P35718 psi-mi:"MI:0469"(intact) crc64:9F913C2FC9EF6E82 crc64:7A2422D5B0CEEEC5 figure legend:tables S3 and S4|author-confidence:99.34|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 rogid:p1dX8gVjuF87lQXJyJUNaY1h9uY559292 intact-crc:2EB8537FFC1B9DC2|rigid:83w20nFxDDS30q0RXHMRYslV38E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35718 uniprotkb:P04051 intact:EBI-15854|uniprotkb:D6VX52|ensemblfungi:YKL144C intact:EBI-15810|ensemblfungi:YOR116C|uniprotkb:D6W2H5 psi-mi:rpc8_yeast(display_long)|uniprotkb:RPC25(gene name)|psi-mi:RPC25(display_short)|uniprotkb:YKL144C(locus name)|uniprotkb:YKL1(orf name)|uniprotkb:UNF1(orf name)|uniprotkb:RNA polymerase III subunit C25(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III 25 kDa polypeptide(gene name synonym) psi-mi:rpc1_yeast(display_long)|uniprotkb:RPO31(gene name)|psi-mi:RPO31(display_short)|uniprotkb:RPC160(gene name synonym)|uniprotkb:RPC1(gene name synonym)|uniprotkb:YOR116C(locus name)|uniprotkb:O3254(orf name)|uniprotkb:YOR3254C(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase III subunit C160(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325152|imex:IM-14275-1022 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012778.1|sgd:S000001627|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|ensemblfungi:YKL144C_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR004519(DNA-directed RNA polymerase)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013238(RNA polymerase III, subunit Rpc25)|interpro:IPR036898|rcsb pdb:2CKZ|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|ensemblfungi:YKL144C(gene)|dip:DIP-1414N|mint:P35718 refseq:NP_014759.1|sgd:S000005642|ensemblfungi:YOR116C(gene)|ensemblfungi:YOR116C_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0046872"(metal ion binding)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR035697|interpro:IPR035698|interpro:IPR038120|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|interpro:IPR042102|dip:DIP-612N|mint:P04051 psi-mi:"MI:0469"(intact) crc64:7A2422D5B0CEEEC5 crc64:D1697EB2352BCA4F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p1dX8gVjuF87lQXJyJUNaY1h9uY559292 rogid:DoIDVE/XVbuQ8WSo+elSj7Ho5Ww559292 intact-crc:B2A275CAAE526B36|rigid:7jYfEpP5SF/wD5EL6XIRQ0drKiI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40368 uniprotkb:P35729 intact:EBI-12331|ensemblfungi:YJL061W|uniprotkb:D6VWC1 intact:EBI-11713|ensemblfungi:YKL057C|uniprotkb:P35730|uniprotkb:D6VXN0 psi-mi:nup82_yeast(display_long)|uniprotkb:NUP82(gene name)|psi-mi:NUP82(display_short)|uniprotkb:YJL061W(locus name)|uniprotkb:J1135(orf name)|uniprotkb:HRB187(orf name)|uniprotkb:Nuclear pore protein NUP82(gene name synonym) psi-mi:nu120_yeast(display_long)|uniprotkb:NUP120(gene name)|psi-mi:NUP120(display_short)|uniprotkb:RAT2(gene name synonym)|uniprotkb:YKL057C(locus name)|uniprotkb:YKL314(orf name)|uniprotkb:YKL313(orf name)|uniprotkb:Nuclear pore protein NUP120(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325174|imex:IM-14275-1024 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012474.1|sgd:S000003597|ensemblfungi:YJL061W(gene)|ensemblfungi:YJL061W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|interpro:IPR037700|rcsb pdb:3PBP|rcsb pdb:3TKN|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|mint:P40368|dip:DIP-913N ensemblfungi:YKL057C(gene)|ensemblfungi:YKL057C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR021717|rcsb pdb:3F7F|go:"GO:0031509"(subtelomeric heterochromatin assembly)|rcsb pdb:3H7N|rcsb pdb:3HXR|rcsb pdb:4XMM|rcsb pdb:4XMN|rcsb pdb:6X06|refseq:NP_012866.1|sgd:S000001540|mint:P35729|dip:DIP-2721N psi-mi:"MI:0469"(intact) crc64:C379B5E111E26B50 crc64:D4655E6116C54503 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:g1+jqOMmde8phrNI9H7nFlXwjH0559292 rogid:8A1GtKeq+kjBvl1iuUd6rIx7yLo559292 intact-crc:CDE73DC5FAB712B7|rigid:NsgiikstjvS/xSRCLhrMHahXsHY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46673 uniprotkb:P35729 intact:EBI-12345|ensemblfungi:YJR042W|uniprotkb:D6VWL3 intact:EBI-11713|ensemblfungi:YKL057C|uniprotkb:P35730|uniprotkb:D6VXN0 psi-mi:nup85_yeast(display_long)|uniprotkb:NUP85(gene name)|psi-mi:NUP85(display_short)|uniprotkb:RAT9(gene name synonym)|uniprotkb:YJR042W(locus name)|uniprotkb:J1624(orf name)|uniprotkb:Nuclear pore protein NUP85(gene name synonym) psi-mi:nu120_yeast(display_long)|uniprotkb:NUP120(gene name)|psi-mi:NUP120(display_short)|uniprotkb:RAT2(gene name synonym)|uniprotkb:YKL057C(locus name)|uniprotkb:YKL314(orf name)|uniprotkb:YKL313(orf name)|uniprotkb:Nuclear pore protein NUP120(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325185|imex:IM-14275-1025 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YJR042W(gene)|ensemblfungi:YJR042W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR011502(Nucleoporin, Nup85-like)|rcsb pdb:3EWE|rcsb pdb:3F3F|rcsb pdb:3F3G|rcsb pdb:3F3P|rcsb pdb:4XMM|rcsb pdb:4XMN|rcsb pdb:6X08|refseq:NP_012576.1|sgd:S000003803|mint:P46673|dip:DIP-5818N ensemblfungi:YKL057C(gene)|ensemblfungi:YKL057C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR021717|rcsb pdb:3F7F|go:"GO:0031509"(subtelomeric heterochromatin assembly)|rcsb pdb:3H7N|rcsb pdb:3HXR|rcsb pdb:4XMM|rcsb pdb:4XMN|rcsb pdb:6X06|refseq:NP_012866.1|sgd:S000001540|mint:P35729|dip:DIP-2721N psi-mi:"MI:0469"(intact) crc64:4C0A4AD3DB57A023 crc64:D4655E6116C54503 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XmACeptHS3SlfgccMUpRYxEA3sI559292 rogid:8A1GtKeq+kjBvl1iuUd6rIx7yLo559292 intact-crc:522C06092CA8904A|rigid:BRwSzCY+YFKCWI079At/OIgru9g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35732 uniprotkb:P25339 intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C intact:EBI-23703|uniprotkb:D6VUC3|ensemblfungi:YGL014W psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:puf4_yeast(display_long)|uniprotkb:PUF4(gene name)|psi-mi:PUF4(display_short)|uniprotkb:YGL023(orf name)|uniprotkb:YGL014W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325196|imex:IM-14275-1026 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 refseq:NP_011501.1|sgd:S000002982|dip:DIP-2638N|mint:P25339|ensemblfungi:YGL014W(gene)|ensemblfungi:YGL014W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:3BWT|rcsb pdb:3BX2|rcsb pdb:3BX3|rcsb pdb:4DZS|go:"GO:0003729"(mRNA binding) psi-mi:"MI:0469"(intact) crc64:05734E2D0B7389AC crc64:659BA1062439F642 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 rogid:spjnSzTKOyi8X0oMi4wOTS+72hY559292 intact-crc:0855F93BB41DD9FB|rigid:NU5bM7b6Jr/+XiqaBneZrZwMDFA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35732 uniprotkb:P25567 intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C intact:EBI-18084|uniprotkb:D6VQX8|ensemblfungi:YCL037C psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:sro9_yeast(display_long)|uniprotkb:SRO9(gene name)|psi-mi:SRO9(display_short)|uniprotkb:YCL037C(locus name)|uniprotkb:YCL37C(orf name)|uniprotkb:Suppressor of RHO3 protein 9(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325207|imex:IM-14275-1027 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 refseq:NP_009893.2|sgd:S000000542|ensemblfungi:YCL037C(gene)|ensemblfungi:YCL037C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|dip:DIP-6638N|mint:P25567 psi-mi:"MI:0469"(intact) crc64:05734E2D0B7389AC crc64:B1B720D40C7B9914 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 rogid:CouwiBsK7S3Tm6CoBsu3LdWfelg559292 intact-crc:12D3BF05C6975A8B|rigid:Y7VclD5M+7aKuQyi/lZi/FPmWTA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35732 uniprotkb:P25644 intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C intact:EBI-204|uniprotkb:Q8NKJ3|uniprotkb:D6VR80|ensemblfungi:YCR077C psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:pat1_yeast(display_long)|uniprotkb:PAT1(gene name)|psi-mi:PAT1(display_short)|uniprotkb:Decapping activator and translational repressor PAT1(gene name synonym)|uniprotkb:mRNA turnover protein 1(gene name synonym)|uniprotkb:MRT1(gene name synonym)|uniprotkb:Topoisomerase II-associated protein PAT1(gene name synonym)|uniprotkb:YCR77C(orf name)|uniprotkb:YCR077C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325218|imex:IM-14275-1028 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 refseq:NP_010002.3|sgd:S000000673|mint:P25644|dip:DIP-883N|ensemblfungi:YCR077C(gene)|ensemblfungi:YCR077C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000776"(kinetochore)|go:"GO:0000932"(P-body)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033962"(P-body assembly)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0051301"(cell division)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR019167|interpro:IPR039900|rcsb pdb:4BRW|rcsb pdb:4C8Q|rcsb pdb:4N0A|rcsb pdb:4OGP|rcsb pdb:4OJJ|rcsb pdb:5LM5|rcsb pdb:5LMF|rcsb pdb:5LMG|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:05734E2D0B7389AC crc64:2DBE1210C173E468 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 rogid:kov8R0RAgIOPffQ7ydjCUxjoE/M559292 intact-crc:2C201C08086AC6F7|rigid:d1mz+T9ewMGSoXSe0wXEfpcHaCE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35732 uniprotkb:P25655 intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325229|imex:IM-14275-1029 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 psi-mi:"MI:0469"(intact) crc64:05734E2D0B7389AC crc64:5B2AE15BCF95E009 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 intact-crc:42411C0CB1AE272D|rigid:+/W1Ec/CmGbDDFL35v92cZt5UhQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32588 uniprotkb:P35732 intact:EBI-14231|ensemblfungi:YNL016W|uniprotkb:D6W1G2 intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C psi-mi:pub1_yeast(display_long)|uniprotkb:ARS consensus-binding protein ACBP-60(gene name synonym)|uniprotkb:Poly uridylate-binding protein(gene name synonym)|uniprotkb:PUB1(gene name)|psi-mi:PUB1(display_short)|uniprotkb:RNP1(gene name synonym)|uniprotkb:YNL016W(locus name)|uniprotkb:N2842(orf name) psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325240|imex:IM-14275-1030 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014382.1|sgd:S000004961|ensemblfungi:YNL016W(gene)|ensemblfungi:YNL016W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043488"(regulation of mRNA stability)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034509|interpro:IPR034639|interpro:IPR035979|rcsb pdb:2LA4|rcsb pdb:3MD1|rcsb pdb:3MD3|rcsb pdb:6Z29|mint:P32588|dip:DIP-5480N refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 psi-mi:"MI:0469"(intact) crc64:3B81A7735505D3CA crc64:05734E2D0B7389AC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8xFMuEva7leVYDKg3WOmvPtRTFk559292 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 intact-crc:7BD8CDF7405397F0|rigid:ViaewK4I9gWtNg5r7qk6Ak7rZn8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35732 uniprotkb:P33891 intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C intact:EBI-19396|uniprotkb:D6VU04|ensemblfungi:YGL145W psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:tip20_yeast(display_long)|uniprotkb:YGL145W(locus name)|uniprotkb:TIP20(gene name)|psi-mi:TIP20(display_short)|uniprotkb:TIP1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325251|imex:IM-14275-1031 author score:99.34 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 refseq:NP_116577.1|sgd:S000003113|ensemblfungi:YGL145W(gene)|ensemblfungi:YGL145W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006914"(autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0070939"(Dsl1/NZR complex)|interpro:IPR007528(RINT-1/TIP-1)|interpro:IPR042040|interpro:IPR042041|interpro:IPR042042|interpro:IPR042043|interpro:IPR042044|rcsb pdb:3ETV|rcsb pdb:3FHN|reactome:R-SCE-6811434|dip:DIP-2004N|mint:P33891 psi-mi:"MI:0469"(intact) crc64:05734E2D0B7389AC crc64:3E561DD4C0B9C176 figure legend:tables S3 and S4|author-confidence:99.34|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 rogid:lOef1qmG8wr6J9Mg5gMA77MvknA559292 intact-crc:72680D67126813D4|rigid:xfrQxGTpUghxgswvKU+ZNxFXwNE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35732 uniprotkb:P34909 intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325262|imex:IM-14275-1032 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 psi-mi:"MI:0469"(intact) crc64:05734E2D0B7389AC crc64:8847084BD9BF48B7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 intact-crc:911022B5D8F6C6D5|rigid:OERlUgdZAnTWZLVY3wlXMpOjZCE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35732 uniprotkb:P35732 intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325273|imex:IM-14275-1033 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 psi-mi:"MI:0469"(intact) crc64:05734E2D0B7389AC crc64:05734E2D0B7389AC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 intact-crc:269479C4E7247241|rigid:j2uK8EFY69LXsOwVDiy+OtTNPD0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35732 uniprotkb:P38009 intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325284|imex:IM-14275-1034 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N psi-mi:"MI:0469"(intact) crc64:05734E2D0B7389AC crc64:8ABA71761B512242 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 intact-crc:5879F4A1687808A9|rigid:QG6S1+D8cE3NGEc32R4p/BjrRcY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39008 uniprotkb:P35732 intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325295|imex:IM-14275-1035 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 psi-mi:"MI:0469"(intact) crc64:F3CAF97106A65933 crc64:05734E2D0B7389AC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 intact-crc:587FAC08F48770D8|rigid:X+25jmd8ZL1DkcT97Z3KY5DW17s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39016 uniprotkb:P35732 intact:EBI-2052996|uniprotkb:D6VTX5|ensemblfungi:YGL178W intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C psi-mi:mpt5_yeast(display_long)|uniprotkb:HTR1(gene name synonym)|uniprotkb:PUF5(gene name synonym)|uniprotkb:Protein HTR1(gene name synonym)|uniprotkb:BIC834(orf name)|uniprotkb:YGL178W(locus name)|uniprotkb:MPT5(gene name)|psi-mi:MPT5(display_short)|uniprotkb:Pumilio homology domain family member 5(gene name synonym) psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325306|imex:IM-14275-1036 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011337.1|sgd:S000003146|dip:DIP-2271N|mint:P39016|ensemblfungi:YGL178W(gene)|ensemblfungi:YGL178W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:5BYM|rcsb pdb:5BZ1|rcsb pdb:5BZ5|rcsb pdb:5BZU|rcsb pdb:5BZV refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 psi-mi:"MI:0469"(intact) crc64:6B289BAF3CEA2200 crc64:05734E2D0B7389AC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tWA8mxLeerefKvNZOERVljO8uHQ559292 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 intact-crc:E57E76E62139B3DB|rigid:E8QwaK9msFCLxP2vwIY2IJb4FzM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39108 uniprotkb:P35732 intact:EBI-13183|uniprotkb:D6VSC5|ensemblfungi:YDR142C intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C psi-mi:pex7_yeast(display_long)|uniprotkb:PEX7(gene name)|psi-mi:PEX7(display_short)|uniprotkb:PAS7(gene name synonym)|uniprotkb:PEB1(gene name synonym)|uniprotkb:YDR142C(locus name)|uniprotkb:YD2943.01C(orf name)|uniprotkb:YD9302.18C(orf name)|uniprotkb:Peroxin-7(gene name synonym)|uniprotkb:Peroxisome import protein PAS7(gene name synonym) psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325317|imex:IM-14275-1037 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010426.1|sgd:S000002549|mint:P39108|dip:DIP-1501N|ensemblfungi:YDR142C(gene)|ensemblfungi:YDR142C_mRNA(transcript)|go:"GO:0005053"(peroxisome matrix targeting signal-2 binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR044536|rcsb pdb:3W15|reactome:R-SCE-9033241 refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 psi-mi:"MI:0469"(intact) crc64:7D53A42A8ACF23F9 crc64:05734E2D0B7389AC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pbZR1BPmg6mCFnJ+JrVh7ffSb5c559292 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 intact-crc:272EF3B1FFA1552C|rigid:qjmUGOX048kLUGOJBtOK2QSIKoo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39517 uniprotkb:P35732 intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325328|imex:IM-14275-1038 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 psi-mi:"MI:0469"(intact) crc64:062CFA56DF6F2CEE crc64:05734E2D0B7389AC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 intact-crc:48D35C9D23735FAA|rigid:K616GIZs4HlO0ognZZvtd5YQ2sQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40070 uniprotkb:P35732 intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325339|imex:IM-14275-1039 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 psi-mi:"MI:0469"(intact) crc64:69CAC1F01D5BFA98 crc64:05734E2D0B7389AC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 intact-crc:B4E23D1CC6A1691C|rigid:dp2KIhWs/hOl68XCYCbREnG2IEI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35732 uniprotkb:P53010 intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C intact:EBI-12887|uniprotkb:D6VU51|ensemblfungi:YGL094C psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:pan2_yeast(display_long)|uniprotkb:PAN2(gene name)|psi-mi:PAN2(display_short)|uniprotkb:"PAB1P-dependent poly(A)-specific ribonuclease"(gene name synonym)|uniprotkb:"Poly(A)-nuclease deadenylation complex subunit 2"(gene name synonym)|uniprotkb:YGL094C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325350|imex:IM-14275-1040 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0006301"(postreplication repair)|go:"GO:0006397"(mRNA processing)|go:"GO:0031251"(PAN complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR028881|interpro:IPR028889|interpro:IPR030843|interpro:IPR036397|interpro:IPR038765|rcsb pdb:4Q8G|rcsb pdb:4Q8H|rcsb pdb:4XR7|rcsb pdb:6R5K|rcsb pdb:6R9I|ensemblfungi:YGL094C(gene)|rcsb pdb:6R9J|rcsb pdb:6R9M|rcsb pdb:6R9O|ensemblfungi:YGL094C_mRNA(transcript)|rcsb pdb:6R9P|rcsb pdb:6R9Q|reactome:R-SCE-429947|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003676"(nucleic acid binding)|refseq:NP_011421.1|sgd:S000003062|mint:P53010|dip:DIP-2466N psi-mi:"MI:0469"(intact) crc64:05734E2D0B7389AC crc64:4F91B737F761AE5A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 rogid:cxjWzuQkjteUDpx+VHb9iZUJenY559292 intact-crc:020DE79786D93191|rigid:FFLrxt3uzGJJM/KBLulawUgFR/0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35732 uniprotkb:P53297 intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C intact:EBI-12961|uniprotkb:D6VUW2|ensemblfungi:YGR178C psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:pbp1_yeast(display_long)|uniprotkb:PBP1(gene name)|psi-mi:PBP1(display_short)|uniprotkb:MRS16(gene name synonym)|uniprotkb:"Poly(A)-binding protein-binding protein"(gene name synonym)|uniprotkb:YGR178C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325361|imex:IM-14275-1041 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 sgd:S000003410|ensemblfungi:YGR178C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0043621"(protein self-association)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1901524"(regulation of mitophagy)|go:"GO:1904262"(negative regulation of TORC1 signaling)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR025852|ensemblfungi:YGR178C(gene)|refseq:NP_011694.3|mint:P53297|dip:DIP-2464N psi-mi:"MI:0469"(intact) crc64:05734E2D0B7389AC crc64:92005F3A2346193E figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 rogid:LtXvbFHbcIwi3NJgeab11QUU2nI559292 intact-crc:A87DA14E58774325|rigid:A0NN99O1ekoFM59w3R+H0Lcqz54 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53829 uniprotkb:P35732 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325372|imex:IM-14275-1042 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 psi-mi:"MI:0469"(intact) crc64:F3DBABE6AD3C7F3C crc64:05734E2D0B7389AC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 intact-crc:79168355BFD0AE22|rigid:7yCl8UNtCDbF4vKoFSX8DSgrFhM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35732 uniprotkb:P57743 intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C intact:EBI-10227|uniprotkb:Q05176|uniprotkb:Q06759|uniprotkb:D6VZ73|ensemblfungi:YLR438C-A psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:lsm3_yeast(display_long)|uniprotkb:LSM3(gene name)|psi-mi:LSM3(display_short)|uniprotkb:SMX4(gene name synonym)|uniprotkb:USS2(gene name synonym)|uniprotkb:YLR438C-A(locus name)|uniprotkb:SmX4 protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325383|imex:IM-14275-1043 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 sgd:S000006434|ensemblfungi:YLR438C-A(gene)|ensemblfungi:YLR438C-A_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034105|interpro:IPR040002|rcsb pdb:3BW1|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:4N0A|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039|rcsb pdb:4M75|refseq:NP_013543.3|dip:DIP-2587N|mint:P57743 psi-mi:"MI:0469"(intact) crc64:05734E2D0B7389AC crc64:787084EF6A5945B7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 rogid:nYl7At1SnlSwN+nWr1F1xm0tdDE559292 intact-crc:74AC7C8B83A99711|rigid:eOQITbNm5vrjc49uhwUUjVSDHaM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P19807 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325405|imex:IM-14275-1045 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:D559A64A87E64034|rigid:UpQcnWrx1LSR4FBYvq42zxyMcpU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10823 uniprotkb:P35735 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325394|imex:IM-14275-1044 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) crc64:881B91792AE91748 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:FD9232317B7AF35A|rigid:H1JumMLYApoN6M2GRn475gHAlRs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25619 uniprotkb:P35735 intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325416|imex:IM-14275-1046 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) crc64:260474A481D29AC5 - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:FDED5EA944BCF9FA|rigid:K8fHtgk2ULI/sh36HrPi+5m48Uw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:P35735 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325427|imex:IM-14275-1047 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) crc64:8B7F009521F72C15 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:129EBF4B098B7CB4|rigid:hWMdGUkW5n/jUv0hrW7IV9apqsE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P29366 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-3508|uniprotkb:D6VQJ6|ensemblfungi:YBR200W psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:bem1_yeast(display_long)|uniprotkb:Suppressor of RHO3 protein 1(gene name synonym)|uniprotkb:BEM1(gene name)|psi-mi:BEM1(display_short)|uniprotkb:SRO1(gene name synonym)|uniprotkb:YBR200W(locus name)|uniprotkb:YBR1412(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325438|imex:IM-14275-1048 author score:93.51 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 sgd:S000000404|refseq:NP_009759.3|dip:DIP-688N|mint:P29366|ensemblfungi:YBR200W(gene)|ensemblfungi:YBR200W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030427"(site of polarized growth)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR030507|interpro:IPR035548|interpro:IPR035549|interpro:IPR035550|interpro:IPR036028|interpro:IPR036871|rcsb pdb:1IP9|rcsb pdb:1IPG|rcsb pdb:2CZO|rcsb pdb:2KFK|rcsb pdb:2RQV|rcsb pdb:2RQW|rcsb pdb:2V6V|reactome:R-SCE-5668599 psi-mi:"MI:0469"(intact) - crc64:FB6C525AE9A19181 figure legend:tables S3 and S4|author-confidence:93.51|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:Fq7WxTviE31ivPWGJoZO5DsUcdg559292 intact-crc:E392B90F8CD8E16C|rigid:+ZtwrgqmexJp6TZASHVuyH1y104 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:P35735 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325449|imex:IM-14275-1049 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:CE569D3624AD53EE|rigid:sI3/uKhwkpIti3+YLchTRwaI6Lc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P32568 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325460|imex:IM-14275-1050 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 intact-crc:0DB9FC0587FAD5CD|rigid:V2c2JGcPYrwW7CpDpi7NDlUkR5s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P33302 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-13038|uniprotkb:D6W2L0|ensemblfungi:YOR153W psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:pdr5_yeast(display_long)|uniprotkb:PDR5(gene name)|psi-mi:PDR5(display_short)|uniprotkb:LEM1(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 5(gene name synonym)|uniprotkb:Suppressor of toxicity of sporidesmin(gene name synonym)|uniprotkb:YOR153W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325471|imex:IM-14275-1051 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 sgd:S000005679|refseq:NP_014796.3|mint:P33302|dip:DIP-6776N|ensemblfungi:YOR153W(gene)|ensemblfungi:YOR153W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR029481|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:Sd6SJWf6B0rDZnLVaPHyvr4lhew559292 intact-crc:EF6255480D51B9A0|rigid:QeaDlxXmWog1+YwMr7EYkIEr2KE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33413 uniprotkb:P35735 intact:EBI-2060312|uniprotkb:D3DKP5|ensemblfungi:YHL016C intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:dur3_yeast(display_long)|uniprotkb:DUR3(gene name)|psi-mi:DUR3(display_short)|uniprotkb:YHL016C(locus name) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325482|imex:IM-14275-1052 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031155|refseq:NP_011847.1|sgd:S000001008|interpro:IPR001734(Na+/solute symporter)|interpro:IPR038377|mint:P33413|ensemblfungi:YHL016C(gene)|ensemblfungi:YHL016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0015204"(urea transmembrane transporter activity)|go:"GO:0015489"(putrescine transmembrane transporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015840"(urea transport)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oTFsdtOngA3q5wCbhK/fpVlIsz0559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:398F724CB48A6A16|rigid:60halaKzwoDYC9uDZuCVRVTdqiQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P35735 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325493|imex:IM-14275-1053 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:9FBB48292C852021|rigid:y6kIjJmzIG+a0ZcwJM+pWimDlZU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:P35735 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325504|imex:IM-14275-1054 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:BDE18AA1BBA7FB75|rigid:uVGTcIClNyf7d+tIfMRXsTWkMTU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P38234 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325515|imex:IM-14275-1055 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 intact-crc:EEAEFC8EBBB143CD|rigid:5r/WW0ljG/Ic6YYSoIHdJv1/dSY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P38695 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325526|imex:IM-14275-1056 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N psi-mi:"MI:0469"(intact) - crc64:6906721BAC1A5F87 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 intact-crc:34103303CFB9C006|rigid:U6bTyBwEGgXY5qK3iD0KT1WYUPI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39719 uniprotkb:P35735 intact:EBI-20703|uniprotkb:Q05165|uniprotkb:D6VPG5|ensemblfungi:YAL053W intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:flc2_yeast(display_long)|uniprotkb:YAL053W(locus name)|uniprotkb:FLC2(gene name)|psi-mi:FLC2(display_short)|uniprotkb:FAD transporter 2(gene name synonym)|uniprotkb:TRP-like ion channel FLC2(gene name synonym) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325537|imex:IM-14275-1057 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009348.2|sgd:S000000049|ensemblfungi:YAL053W(gene)|ensemblfungi:YAL053W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241|go:"GO:0055085"(transmembrane transport)|dip:DIP-6708N|mint:P39719 refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:NOmMW54DNa0o7vM945DlZgVUy44559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:7D2F8015F4C8EAD1|rigid:Wd0A9YJsnvImL7Whq7zUIhP3+T8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P40260 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-10714|ensemblfungi:YGR121C|uniprotkb:D6VUQ2 psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:mep1_yeast(display_long)|uniprotkb:MEP1(gene name)|psi-mi:MEP1(display_short)|uniprotkb:YGR121C(locus name)|uniprotkb:G6331(orf name)|uniprotkb:AMT1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325548|imex:IM-14275-1058 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 ensemblfungi:YGR121C(gene)|ensemblfungi:YGR121C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|sgd:S000003353|refseq:NP_011636.3|mint:P40260|dip:DIP-5530N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:VnoBl5jhQD24N0SbCLv68HCwl1U559292 intact-crc:3C1F3B7AC4A41F64|rigid:j7JPGYzF4LVdZmL1QbRaQl5FUPA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P40474 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325559|imex:IM-14275-1059 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 intact-crc:50436F7F4F844E50|rigid:Qru55Plqyc/au/nR3BnIdE8HbUg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40994 uniprotkb:P35735 intact:EBI-2824|uniprotkb:D6W2F5|ensemblfungi:YOR094W intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:arf3_yeast(display_long)|uniprotkb:ARF3(gene name)|psi-mi:ARF3(display_short)|uniprotkb:YOR3172W(orf name)|uniprotkb:YOR094W(locus name) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325570|imex:IM-14275-1060 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014737.1|sgd:S000005620|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P40994|interpro:IPR041838|ensemblfungi:YOR094W(gene)|ensemblfungi:YOR094W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010513"(positive regulation of phosphatidylinositol biosynthetic process)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0036267"(invasive filamentous growth)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:uC+fupPUZajD7m7pLEO/K0Kuudo559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:85E1ED89D4F848E0|rigid:jE9KblwNFhRnpZmb2TCYt3i05PM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P35735 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325581|imex:IM-14275-1061 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:5D3907F4610125E6|rigid:JszBnD/iu/frW+6cO/sj0qAH1Qs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P53049 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325592|imex:IM-14275-1062 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 intact-crc:735DE8B80051718B|rigid:KKxSF7T+6KiKnw4thc8zQLqBi94 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P53139 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-23908|uniprotkb:D6VU38|ensemblfungi:YGL108C psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:ygk8_yeast(display_long)|uniprotkb:G3070(orf name)|uniprotkb:YGL108C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325603|imex:IM-14275-1063 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 sgd:S000003076|refseq:NP_011407.3|mint:P53139|ensemblfungi:YGL108C(gene)|ensemblfungi:YGL108C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:6rg2zcMN57peeKKy/RolIDcNaLc559292 intact-crc:EA929830F98E99E4|rigid:TiOtD4fAyWBMpGwoPR2MrIpahO0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P53278 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325614|imex:IM-14275-1064 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome) psi-mi:"MI:0469"(intact) - crc64:D482327C9274C026 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292 intact-crc:81A697F1598778D5|rigid:35yoljdrgxjhf26wc9JbjLp1jw8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P53283 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325626|imex:IM-14275-1065 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 intact-crc:70C634C2DBEF07E6|rigid:wD8msNZeOvp2/Oq03bW4GKpXP74 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53390 uniprotkb:P35735 intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325637|imex:IM-14275-1066 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) crc64:2309338F36D96258 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:6E03CF1A98F034B1|rigid:ZmpY39FwRTZT6agA2WyMTBs/43w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53832 uniprotkb:P35735 intact:EBI-2055941|uniprotkb:D6W0R1|ensemblfungi:YNL283C intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:wsc2_yeast(display_long)|uniprotkb:YNL283C(locus name)|uniprotkb:N0583(orf name)|uniprotkb:WSC2(gene name)|psi-mi:WSC2(display_short) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325648|imex:IM-14275-1067 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014116.1|sgd:S000005227|interpro:IPR002889(Carbohydrate-binding WSC)|mint:P53832|ensemblfungi:YNL283C(gene)|ensemblfungi:YNL283C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5wadvTv6SxcIAb60yfnuGMfa8pY559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:F24D0D7AEA2783E8|rigid:QujojyNc7D8ZHZB4L9pwnBsbz8k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02785 uniprotkb:P35735 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325659|imex:IM-14275-1068 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:393BD3BFE961C8A9|rigid:gGyB1qdmmnOnv0SCBn+jd2krT/c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:P35735 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325670|imex:IM-14275-1069 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:770BD69240D19FF4|rigid:q5S/W8pA+xZENNHNgHStMRq1pGI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:Q05812 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-33150|uniprotkb:Q7LIF4|uniprotkb:D6VYL9|ensemblfungi:YLR219W psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:msc3_yeast(display_long)|uniprotkb:MSC3(gene name)|psi-mi:MSC3(display_short)|uniprotkb:YLR219W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325681|imex:IM-14275-1070 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 sgd:S000004209|refseq:NP_013320.1|mint:Q05812|dip:DIP-6321N|ensemblfungi:YLR219W(gene)|ensemblfungi:YLR219W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007131"(reciprocal meiotic recombination) psi-mi:"MI:0469"(intact) - crc64:1962D638DB602B71 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:xS8zCG9eHY8V0vNstOwUuTcI3Ao559292 intact-crc:F4B646664054213D|rigid:sUUvX6nS0MmyUbCGhW7xhsPGq+Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:Q06170 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-35994|uniprotkb:D6VYW8|ensemblfungi:YLR326W psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:yl326_yeast(display_long)|uniprotkb:YLR326W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325692|imex:IM-14275-1071 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 refseq:NP_013430.1|sgd:S000004318|mint:Q06170|dip:DIP-3995N|ensemblfungi:YLR326W(gene)|ensemblfungi:YLR326W_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR025187 psi-mi:"MI:0469"(intact) - crc64:724CD7833AA9B416 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:Ufkoj1kRp4Y9JTsgbL+3k8hzJyo559292 intact-crc:191F9781466AC469|rigid:BtAcNFlwtb8CeqdTxFeEjbxPPkY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:Q06451 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-34275|uniprotkb:D6W4F2|ensemblfungi:YPR156C psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:tpo3_yeast(display_long)|uniprotkb:TPO3(gene name)|psi-mi:TPO3(display_short)|uniprotkb:P9584.7(orf name)|uniprotkb:YPR156C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325703|imex:IM-14275-1072 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 refseq:NP_015482.1|sgd:S000006360|mint:Q06451|dip:DIP-3907N|ensemblfungi:YPR156C(gene)|ensemblfungi:YPR156C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - crc64:D260ED161F800502 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:oVpx7Bjk/mK2Q7+/j05tX3gHw7k559292 intact-crc:560DCFEC086BC0A4|rigid:1V2HBjwLx1NHHNFltmVczqMwyik false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:Q06689 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-38659|uniprotkb:D6VZ50|ensemblfungi:YLR413W psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:yl413_yeast(display_long)|uniprotkb:YLR413W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325714|imex:IM-14275-1073 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 refseq:NP_013517.1|sgd:S000004405|mint:Q06689|dip:DIP-5075N|ensemblfungi:YLR413W(gene)|ensemblfungi:YLR413W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0071944"(cell periphery)|interpro:IPR009571(SUR7) psi-mi:"MI:0469"(intact) - crc64:92E23436DC857E95 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:AoTGKjLhw0NECrtuftZqLANonds559292 intact-crc:ABBBBCD1BE18FE3E|rigid:m/mdpf5XQCt0vRi4es22Hr0/QQ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P35735 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325725|imex:IM-14275-1074 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:371021C1A72CAD69|rigid:OuSSx7XvkNim9Tdqhnbv84ZUxFI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:Q07824 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325736|imex:IM-14275-1075 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 intact-crc:C9BE15108415B46E|rigid:DhNPCT2bY4G+kktyd89Uy8y5VFE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08967 uniprotkb:P35735 intact:EBI-36673|uniprotkb:D6W3E9|ensemblfungi:YPL221W intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:flc1_yeast(display_long)|uniprotkb:FAD transporter 1(gene name synonym)|uniprotkb:FLC1(gene name)|psi-mi:FLC1(display_short)|uniprotkb:TRP-like ion channel protein FLC1(gene name synonym)|uniprotkb:Heme utilization factor 1(gene name synonym)|uniprotkb:Bypass of PAM1 protein 1(gene name synonym)|uniprotkb:HUF1(gene name synonym)|uniprotkb:YPL221W(locus name)|uniprotkb:BOP1(gene name synonym) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325747|imex:IM-14275-1076 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015103.1|sgd:S000006142|mint:Q08967|dip:DIP-3965N|ensemblfungi:YPL221W(gene)|ensemblfungi:YPL221W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055085"(transmembrane transport)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241 refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:r6CcZGEjxHUk2w0iBUBvnAPaFd4559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:809C8F8C9ED061C8|rigid:THD0Q7qo4WF98Zs/W2QrXkTn+30 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:Q12256 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325758|imex:IM-14275-1077 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 intact-crc:C4D7C5A770E71482|rigid:bZlI3dBgI1qCxpPhP90B0GQmQWo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12335 uniprotkb:P35735 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325769|imex:IM-14275-1078 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) crc64:1056E7A1F3E82288 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:3C8C114EC101EA4E|rigid:HtNvIZzp6gB8/qHDLVc5xrRNXJc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3E756 uniprotkb:P35735 intact:EBI-2044812|uniprotkb:D6VPX0|ensemblfungi:YBL029C-A intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:yb029_yeast(display_long)|uniprotkb:YBL029C-A(locus name) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325780|imex:IM-14275-1079 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000007591|refseq:NP_076874.1|mint:Q3E756|ensemblfungi:YBL029C-A(gene)|ensemblfungi:YBL029C-A_mRNA(transcript)|go:"GO:0005886"(plasma membrane) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Y9LDkESr65DK5SLFNTw1dBKeqPc559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:5F0CEDB31561A930|rigid:qQGmDeHQdLLuY722CEhtWG6Ce1M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35845 uniprotkb:P35845 intact:EBI-12611|uniprotkb:P39555|uniprotkb:P80234|uniprotkb:Q86ZC4|uniprotkb:Q86ZS1|uniprotkb:D6VPN6|ensemblfungi:YAR042W intact:EBI-12611|uniprotkb:P39555|uniprotkb:P80234|uniprotkb:Q86ZC4|uniprotkb:Q86ZS1|uniprotkb:D6VPN6|ensemblfungi:YAR042W psi-mi:osh1_yeast(display_long)|uniprotkb:SWH1(gene name)|psi-mi:SWH1(display_short)|uniprotkb:OSH1(gene name synonym)|uniprotkb:YAR044W(orf name)|uniprotkb:YAR042W(locus name) psi-mi:osh1_yeast(display_long)|uniprotkb:SWH1(gene name)|psi-mi:SWH1(display_short)|uniprotkb:OSH1(gene name synonym)|uniprotkb:YAR044W(orf name)|uniprotkb:YAR042W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325791|imex:IM-14275-1080 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YAR042W(gene)|ensemblfungi:YAR042W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0005829"(cytosol)|go:"GO:0008289"(lipid binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR036770|interpro:IPR037239|rcsb pdb:5H28|rcsb pdb:5H2C|reactome:R-SCE-192105|refseq:NP_009421.3|sgd:S000000081|mint:P35845|dip:DIP-6839N ensemblfungi:YAR042W(gene)|ensemblfungi:YAR042W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0005829"(cytosol)|go:"GO:0008289"(lipid binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR036770|interpro:IPR037239|rcsb pdb:5H28|rcsb pdb:5H2C|reactome:R-SCE-192105|refseq:NP_009421.3|sgd:S000000081|mint:P35845|dip:DIP-6839N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Uag2eKjjL7ua+oy/CfVq+g9FORU559292 rogid:Uag2eKjjL7ua+oy/CfVq+g9FORU559292 intact-crc:9CC92BFFA9B78EBC|rigid:7TS0WwYO+AKd8qV6iycieJNrm5c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35845 uniprotkb:P39968 intact:EBI-12611|uniprotkb:P39555|uniprotkb:P80234|uniprotkb:Q86ZC4|uniprotkb:Q86ZS1|uniprotkb:D6VPN6|ensemblfungi:YAR042W intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W psi-mi:osh1_yeast(display_long)|uniprotkb:SWH1(gene name)|psi-mi:SWH1(display_short)|uniprotkb:OSH1(gene name synonym)|uniprotkb:YAR044W(orf name)|uniprotkb:YAR042W(locus name) psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325802|imex:IM-14275-1081 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YAR042W(gene)|ensemblfungi:YAR042W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0005829"(cytosol)|go:"GO:0008289"(lipid binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR036770|interpro:IPR037239|rcsb pdb:5H28|rcsb pdb:5H2C|reactome:R-SCE-192105|refseq:NP_009421.3|sgd:S000000081|mint:P35845|dip:DIP-6839N sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N psi-mi:"MI:0469"(intact) - crc64:B2E75774B47E5933 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Uag2eKjjL7ua+oy/CfVq+g9FORU559292 rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292 intact-crc:9EB5B75C5F283FEC|rigid:KN774VL/vjY5pJoySYGo0huBmNg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36003 uniprotkb:P23202 intact:EBI-9796|ensemblfungi:YKL171W|uniprotkb:D6VX29|intact:EBI-2640274 intact:EBI-20138|uniprotkb:D6W0W3|ensemblfungi:YNL229C psi-mi:nnk1_yeast(display_long)|uniprotkb:YKL635(orf name)|uniprotkb:YKL171W(locus name)|uniprotkb:NNK1(gene name)|psi-mi:NNK1(display_short) psi-mi:ure2_yeast(display_long)|uniprotkb:URE2(gene name)|psi-mi:URE2(display_short)|uniprotkb:Disulfide reductase(gene name synonym)|uniprotkb:Glutathione peroxidase(gene name synonym)|uniprotkb:N1165(orf name)|uniprotkb:YNL229C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325813|imex:IM-14275-1082 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012750.1|sgd:S000001654|ensemblfungi:YKL171W(gene)|ensemblfungi:YKL171W_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0005634"(nucleus)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016241(Serine/threonine-protein kinase YKL171W, predicted)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P36003|dip:DIP-2877N refseq:NP_014170.1|sgd:S000005173|ensemblfungi:YNL229C(gene)|ensemblfungi:YNL229C_mRNA(transcript)|mint:P23202|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0010044"(response to aluminum ion)|go:"GO:0032447"(protein urmylation)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR017298(Prion URE2)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:1G6W|rcsb pdb:1G6Y|rcsb pdb:1HQO|rcsb pdb:1JZR|rcsb pdb:1K0A|rcsb pdb:1K0B|rcsb pdb:1K0C|rcsb pdb:1K0D|go:"GO:0003714"(transcription corepressor activity)|dip:DIP-1308N psi-mi:"MI:0469"(intact) crc64:00EB03553EC5999A crc64:2C628976034B0F1C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UoodKyeNlp+wzbiMHqPRy6TEVoA559292 rogid:jjsWygBsEp8axNurMa3pxPMQJ2k559292 intact-crc:B03156A120ED4E66|rigid:nKvIJqw13oFzSjCrP6vgu1JL2ew false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36009 uniprotkb:P53874 intact:EBI-5844|ensemblfungi:YKL078W|uniprotkb:Q07040|uniprotkb:D6VXK9 intact:EBI-19873|uniprotkb:D6W101|ensemblfungi:YNL186W psi-mi:dhr2_yeast(display_long)|uniprotkb:DHR2(gene name)|psi-mi:DHR2(display_short)|uniprotkb:YKL078W(locus name)|uniprotkb:YKL408(orf name)|uniprotkb:DEAH box RNA helicase DHR2(gene name synonym)|uniprotkb:Helicase JA2(gene name synonym) psi-mi:ubp10_yeast(display_long)|uniprotkb:UBP10(gene name)|psi-mi:UBP10(display_short)|uniprotkb:YNL186W(locus name)|uniprotkb:N1619(orf name)|uniprotkb:Ubiquitin-specific-processing protease 10(gene name synonym)|uniprotkb:Deubiquitinating enzyme 10(gene name synonym)|uniprotkb:Disrupter of telomere silencing protein 4(gene name synonym)|uniprotkb:Ubiquitin thioesterase 10(gene name synonym)|uniprotkb:DOT4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325824|imex:IM-14275-1083 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YKL078W(gene)|ensemblfungi:YKL078W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|refseq:NP_012845.1|sgd:S000001561|dip:DIP-6424N|mint:P36009|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417 refseq:NP_014213.2|sgd:S000005130|ensemblfungi:YNL186W(gene)|ensemblfungi:YNL186W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0043596"(nuclear replication fork)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|rcsb pdb:6RR0|dip:DIP-6664N|mint:P53874 psi-mi:"MI:0469"(intact) crc64:AAFA78B5F6215D89 - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UneKv9+4eIsC09fOzm8AvKCOCVs559292 rogid:Z1rRAI9RLgHeGd7QwLbrf51v5LY559292 intact-crc:7589C516BD7B8170|rigid:Cs+XSXruyRkFZg+Jf143JV6l6cU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36010 uniprotkb:P36010 intact:EBI-11968|ensemblfungi:YKL067W|uniprotkb:D6VXM0 intact:EBI-11968|ensemblfungi:YKL067W|uniprotkb:D6VXM0 psi-mi:ndk_yeast(display_long)|uniprotkb:YNK1(gene name)|psi-mi:YNK1(display_short)|uniprotkb:YNK(gene name synonym)|uniprotkb:NDK1(gene name synonym)|uniprotkb:YKL067W(locus name)|uniprotkb:YKL333(orf name) psi-mi:ndk_yeast(display_long)|uniprotkb:YNK1(gene name)|psi-mi:YNK1(display_short)|uniprotkb:YNK(gene name synonym)|uniprotkb:NDK1(gene name synonym)|uniprotkb:YKL067W(locus name)|uniprotkb:YKL333(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325835|imex:IM-14275-1084 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|rcsb pdb:3B54|reactome:R-SCE-499943|reactome:R-SCE-6798695|ensemblfungi:YKL067W(gene)|ensemblfungi:YKL067W_mRNA(transcript)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|refseq:NP_012856.1|sgd:S000001550|mint:P36010|dip:DIP-1969N go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|rcsb pdb:3B54|reactome:R-SCE-499943|reactome:R-SCE-6798695|ensemblfungi:YKL067W(gene)|ensemblfungi:YKL067W_mRNA(transcript)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|refseq:NP_012856.1|sgd:S000001550|mint:P36010|dip:DIP-1969N psi-mi:"MI:0469"(intact) crc64:BE37ACED90A44D00 crc64:BE37ACED90A44D00 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zMqoKDqnnrvFtHYoZon4yvNQsnI559292 rogid:zMqoKDqnnrvFtHYoZon4yvNQsnI559292 intact-crc:256366FB69FE49E8|rigid:YTBDTR7DhU6KEpyeWH9suP+SqlA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53135 uniprotkb:P36014 intact:EBI-23925|uniprotkb:D6VU34|ensemblfungi:YGL113W intact:EBI-7857|uniprotkb:D6VXQ8|ensemblfungi:YKL026C psi-mi:sld3_yeast(display_long)|uniprotkb:SLD3(gene name)|psi-mi:SLD3(display_short)|uniprotkb:G2980(orf name)|uniprotkb:YGL113W(locus name) psi-mi:gpx1_yeast(display_long)|uniprotkb:GPX1(gene name)|psi-mi:GPX1(display_short)|uniprotkb:Glutathione peroxidase homolog 1(gene name synonym)|uniprotkb:YKL026C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325846|imex:IM-14275-1085 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003081|refseq:NP_011402.3|dip:DIP-5481N|mint:P53135|ensemblfungi:YGL113W(gene)|ensemblfungi:YGL113W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR013948(DNA replication regulator Sld3)|interpro:IPR041393|interpro:IPR042511|rcsb pdb:3WI3 sgd:S000001509|refseq:NP_012899.3|dip:DIP-5437N|mint:P36014|ensemblfungi:YKL026C(gene)|ensemblfungi:YKL026C_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0007031"(peroxisome organization)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR029759|interpro:IPR029760|interpro:IPR036249|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661 psi-mi:"MI:0469"(intact) crc64:6E59D0DB3C082C28 - figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1uxenWX3lYYMDUWr0mAE207XsHI559292 rogid:9BoVR8WeKNUFheWJ/ubAQ4o2aYE559292 intact-crc:18F53C4EFDC146C9|rigid:mdUQqxqFSJm5rmsL2LSVbxHLXoY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06776 uniprotkb:P36016 intact:EBI-4780|uniprotkb:Q08836|uniprotkb:D6W355|ensemblfungi:YOR360C intact:EBI-10154|uniprotkb:D6VXL3|ensemblfungi:YKL073W psi-mi:pde2_yeast(display_long)|uniprotkb:PDE2(gene name)|psi-mi:PDE2(display_short)|uniprotkb:SRA5(gene name synonym)|uniprotkb:YOR360C(locus name)|uniprotkb:High-affinity cAMP phosphodiesterase(gene name synonym) psi-mi:lhs1_yeast(display_long)|uniprotkb:YKL355(orf name)|uniprotkb:YKL073W(locus name)|uniprotkb:LHS1(gene name)|psi-mi:LHS1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325857|imex:IM-14275-1086 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015005.1|sgd:S000005887|dip:DIP-4055N|mint:P06776|ensemblfungi:YOR360C(gene)|ensemblfungi:YOR360C_mRNA(transcript)|go:"GO:0004114"(3',5'-cyclic-nucleotide phosphodiesterase activity)|go:"GO:0004115"(3',5'-cyclic-AMP phosphodiesterase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0046872"(metal ion binding)|interpro:IPR002073(3'5'-cyclic nucleotide phosphodiesterase)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR023088|interpro:IPR023174|interpro:IPR036971|reactome:R-SCE-418457|reactome:R-SCE-418555 refseq:NP_012850.1|sgd:S000001556|ensemblfungi:YKL073W(gene)|ensemblfungi:YKL073W_mRNA(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029048|interpro:IPR043129|dip:DIP-6520N|mint:P36016 psi-mi:"MI:0469"(intact) - crc64:ACED092CA3A34785 figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8I+yKEcjCVFgenC1RIzic2Iqb5M559292 rogid:Qs4KLBROFUy9xwsA3gOCcTT/iGo559292 intact-crc:583A554D940FCE20|rigid:w/qpVX7ZZ3EJseXAsAiA4A9icW4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32864 uniprotkb:P36017 intact:EBI-14799|uniprotkb:Q06761|uniprotkb:D6W363|ensemblfungi:YOR370C intact:EBI-29399|uniprotkb:D6W2F0|ensemblfungi:YOR089C psi-mi:raep_yeast(display_long)|uniprotkb:YOR370C(locus name)|uniprotkb:MRS6(gene name)|psi-mi:MRS6(display_short)|uniprotkb:MSI4(gene name synonym)|uniprotkb:Rab escort protein(gene name synonym) psi-mi:vps21_yeast(display_long)|uniprotkb:GTP-binding protein YPT51(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 12(gene name synonym)|uniprotkb:VPS21(gene name)|psi-mi:VPS21(display_short)|uniprotkb:YOR089C(locus name)|uniprotkb:YOR3154C(orf name)|uniprotkb:VPS12(gene name synonym)|uniprotkb:VPT12(gene name synonym)|uniprotkb:YPT21(gene name synonym)|uniprotkb:YPT51(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325868|imex:IM-14275-1087 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015015.1|sgd:S000005897|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005968"(Rab-protein geranylgeranyltransferase complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR017230(Rab protein geranylgeranyltransferase, component A, fungi)|interpro:IPR018203|interpro:IPR036188|reactome:R-SCE-6803205|reactome:R-SCE-8873719|reactome:R-SCE-8876198|ensemblfungi:YOR370C(gene)|ensemblfungi:YOR370C_mRNA(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|dip:DIP-2246N|mint:P32864 refseq:NP_014732.1|sgd:S000005615|dip:DIP-3801N|mint:P36017|ensemblfungi:YOR089C(gene)|ensemblfungi:YOR089C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0061709"(reticulophagy)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1EK0 psi-mi:"MI:0469"(intact) crc64:30BB7FFF8D712FFD crc64:34D7DA0090C33F09 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:quu5u+3WZxRJAobk3H2EERRUqKU559292 rogid:fo/U32XQLnHSVpuK48jddD4Kve4559292 intact-crc:922A18A764AF1230|rigid:21+hrBtVxOoLlfY6gpFme+ctaBI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36017 uniprotkb:P39958 intact:EBI-29399|uniprotkb:D6W2F0|ensemblfungi:YOR089C intact:EBI-7517|uniprotkb:D3DM41|ensemblfungi:YER136W psi-mi:vps21_yeast(display_long)|uniprotkb:GTP-binding protein YPT51(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 12(gene name synonym)|uniprotkb:VPS21(gene name)|psi-mi:VPS21(display_short)|uniprotkb:YOR089C(locus name)|uniprotkb:YOR3154C(orf name)|uniprotkb:VPS12(gene name synonym)|uniprotkb:VPT12(gene name synonym)|uniprotkb:YPT21(gene name synonym)|uniprotkb:YPT51(gene name synonym) psi-mi:gdi1_yeast(display_long)|uniprotkb:YER136W(locus name)|uniprotkb:GDI1(gene name)|psi-mi:GDI1(display_short)|uniprotkb:SEC19(gene name synonym)|uniprotkb:Secretory pathway GDP dissociation inhibitor(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325879|imex:IM-14275-1088 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014732.1|sgd:S000005615|dip:DIP-3801N|mint:P36017|ensemblfungi:YOR089C(gene)|ensemblfungi:YOR089C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0061709"(reticulophagy)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1EK0 refseq:NP_011062.1|sgd:S000000938|mint:P39958|dip:DIP-785N|ensemblfungi:YER136W(gene)|ensemblfungi:YER136W_mRNA(transcript)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|rcsb pdb:1UKV|rcsb pdb:2BCG|rcsb pdb:3CPH|rcsb pdb:3CPI|rcsb pdb:3CPJ|reactome:R-SCE-6798695|reactome:R-SCE-8876198 psi-mi:"MI:0469"(intact) crc64:34D7DA0090C33F09 crc64:48CF8D45FC031772 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fo/U32XQLnHSVpuK48jddD4Kve4559292 rogid:AkWsG1VUBGxajiAMw0e0mOljZ6s559292 intact-crc:0CC845EB59D86A78|rigid:fj4h+mUV058Rg4TZRQkWxtsYhpE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6Q5K6 uniprotkb:P36017 intact:EBI-392766|ensemblfungi:YML058W-A|uniprotkb:D6VZB5 intact:EBI-29399|uniprotkb:D6W2F0|ensemblfungi:YOR089C psi-mi:hug1_yeast(display_long)|uniprotkb:HUG1(gene name)|psi-mi:HUG1(display_short)|uniprotkb:YML058W-A(locus name) psi-mi:vps21_yeast(display_long)|uniprotkb:GTP-binding protein YPT51(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 12(gene name synonym)|uniprotkb:VPS21(gene name)|psi-mi:VPS21(display_short)|uniprotkb:YOR089C(locus name)|uniprotkb:YOR3154C(orf name)|uniprotkb:VPS12(gene name synonym)|uniprotkb:VPT12(gene name synonym)|uniprotkb:YPT21(gene name synonym)|uniprotkb:YPT51(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325890|imex:IM-14275-1089 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML058W-A(gene)|ensemblfungi:YML058W-A_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:1905117"(regulation of ribonucleoside-diphosphate reductase activity)|go:"GO:1990846"(ribonucleoside-diphosphate reductase inhibitor activity)|sgd:S000007472|refseq:NP_219498.1|mint:Q6Q5K6 refseq:NP_014732.1|sgd:S000005615|dip:DIP-3801N|mint:P36017|ensemblfungi:YOR089C(gene)|ensemblfungi:YOR089C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0061709"(reticulophagy)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1EK0 psi-mi:"MI:0469"(intact) - crc64:34D7DA0090C33F09 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:x+quBrnP+8yql7JGQ1NK4j5ubbw559292 rogid:fo/U32XQLnHSVpuK48jddD4Kve4559292 intact-crc:1F9FEB522BA90AF6|rigid:M/TP0ejWJxVjOc9HV9W3XopCUDg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36024 uniprotkb:P26570 intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym) psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325901|imex:IM-14275-1090 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024 ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N psi-mi:"MI:0469"(intact) - crc64:8B7F009521F72C15 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 intact-crc:200F60A9F0B5451D|rigid:u4cf20lMa8VKz3P+Y3/CNTQFeoo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36024 uniprotkb:P36024 intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym) psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325912|imex:IM-14275-1091 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024 refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292 rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292 intact-crc:ADC4816C6C60C7F9|rigid:0CU9nz1yBj2N3x8ksTEyp+YYVI4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36024 uniprotkb:P36076 intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym) psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325923|imex:IM-14275-1092 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024 refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292 rogid:Li7vZOassm4PC5fW111/j5ivgEc559292 intact-crc:2697CA07993A5E77|rigid:w+Dyw0kudYkd6B6rHxz3iztH/AA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:P19807 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325934|imex:IM-14275-1093 author score:96.02 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:96.02|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:F70004C219549B60|rigid:/mS1VYLraPVziGDiozsJyXHU+Vk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:P35735 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325945|imex:IM-14275-1094 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:3C207099A5CACFFB|rigid:uVGTcIClNyf7d+tIfMRXsTWkMTU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:P36027 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325956|imex:IM-14275-1095 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:BE0F9C0BC5F68DC2|rigid:ACXoszhipRu3LtGPINexu8YwsFY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:P50276 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325967|imex:IM-14275-1096 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:5ED7115E1F505351|rigid:BkMCgCVQO+3ro0/NjPY6GZf+6fc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:P53139 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-23908|uniprotkb:D6VU38|ensemblfungi:YGL108C psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:ygk8_yeast(display_long)|uniprotkb:G3070(orf name)|uniprotkb:YGL108C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325978|imex:IM-14275-1097 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N sgd:S000003076|refseq:NP_011407.3|mint:P53139|ensemblfungi:YGL108C(gene)|ensemblfungi:YGL108C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:6rg2zcMN57peeKKy/RolIDcNaLc559292 intact-crc:E97C8E9A866FEF53|rigid:D1L5LJB0+A8k8fgFMPI15DqsI8k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:Q02785 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6325989|imex:IM-14275-1098 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:3AD5C5159730BE1E|rigid:AnsRLzEaDbVu9ymD4arn6rMu2Rs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35732 uniprotkb:P36041 intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C intact:EBI-26995|uniprotkb:D6VWZ9|ensemblfungi:YKL204W psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:eap1_yeast(display_long)|uniprotkb:YKL204W(locus name)|uniprotkb:EAP1(gene name)|psi-mi:EAP1(display_short)|uniprotkb:eIF4E-associated protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326000|imex:IM-14275-1099 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 sgd:S000001687|refseq:NP_012718.1|mint:P36041|dip:DIP-1778N|ensemblfungi:YKL204W(gene)|ensemblfungi:YKL204W_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005844"(polysome)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0040008"(regulation of growth)|rcsb pdb:6FC1|rcsb pdb:6FC2 psi-mi:"MI:0469"(intact) crc64:05734E2D0B7389AC crc64:775F73F57BB0EF2B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 rogid:ZEiEPALuQ6tOMTZGsuehDPePUxE559292 intact-crc:8D77DC689F43FA0A|rigid:SfhmZmnUoldBqpHBzTUCIns38fk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36047 uniprotkb:P38634 intact:EBI-16783|ensemblfungi:YKL193C|uniprotkb:D6VX07 intact:EBI-17127|ensemblfungi:YLR079W|uniprotkb:D6VY79 psi-mi:sds22_yeast(display_long)|uniprotkb:YKL193C(locus name)|uniprotkb:SDS22(gene name)|psi-mi:SDS22(display_short)|uniprotkb:EGP1(gene name synonym) psi-mi:sic1_yeast(display_long)|uniprotkb:SIC1(gene name)|psi-mi:SIC1(display_short)|uniprotkb:SDB25(gene name synonym)|uniprotkb:YLR079W(locus name)|uniprotkb:L9449.8(orf name)|uniprotkb:CDK inhibitor p40(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326011|imex:IM-14275-1100 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032675|interpro:IPR003591(Leucine-rich repeat, typical subtype)|ensemblfungi:YKL193C(gene)|ensemblfungi:YKL193C_mRNA(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR001611(Leucine-rich repeat)|refseq:NP_012728.1|sgd:S000001676|dip:DIP-2378N|mint:P36047 ensemblfungi:YLR079W(gene)|ensemblfungi:YLR079W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016242"(negative regulation of macroautophagy)|rcsb pdb:3V7D|rcsb pdb:6G86|refseq:NP_013180.1|sgd:S000004069|dip:DIP-6817N|mint:P38634 psi-mi:"MI:0469"(intact) crc64:1EF434C7276ABAEA crc64:7913636340678F78 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0EB+IWHQJapt77CfEgNmk733koU559292 rogid:qU8ivBCZHvG4VmXDxv52yc08Hwc559292 intact-crc:73439610F2F7B7FA|rigid:OBulri5XjNFVTYrNHtMBPZAMDrY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36047 uniprotkb:P43587 intact:EBI-16783|ensemblfungi:YKL193C|uniprotkb:D6VX07 intact:EBI-22913|uniprotkb:D6VTN3|ensemblfungi:YFR003C psi-mi:sds22_yeast(display_long)|uniprotkb:YKL193C(locus name)|uniprotkb:SDS22(gene name)|psi-mi:SDS22(display_short)|uniprotkb:EGP1(gene name synonym) psi-mi:ypi1_yeast(display_long)|uniprotkb:YFR003C(locus name)|uniprotkb:YPI1(gene name)|psi-mi:YPI1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326022|imex:IM-14275-1101 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032675|interpro:IPR003591(Leucine-rich repeat, typical subtype)|ensemblfungi:YKL193C(gene)|ensemblfungi:YKL193C_mRNA(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR001611(Leucine-rich repeat)|refseq:NP_012728.1|sgd:S000001676|dip:DIP-2378N|mint:P36047 refseq:NP_116658.1|sgd:S000001899|dip:DIP-5442N|mint:P43587|ensemblfungi:YFR003C(gene)|ensemblfungi:YFR003C_mRNA(transcript)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006873"(cellular ion homeostasis)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1900180"(regulation of protein localization to nucleus)|interpro:IPR011107(Protein phosphatase inhibitor) psi-mi:"MI:0469"(intact) crc64:1EF434C7276ABAEA crc64:E191184DCD5EF8A1 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0EB+IWHQJapt77CfEgNmk733koU559292 rogid:9O1nEkPevKE4PL5c7cu+WdqATL8559292 intact-crc:F3D32F8E47ABEFB8|rigid:YMJLsDFxbkz58clDEj8So731BQA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36048 uniprotkb:P35194 intact:EBI-243|uniprotkb:D6VX27|ensemblfungi:YKL173W intact:EBI-1871|uniprotkb:D6VPZ8|ensemblfungi:YBL004W psi-mi:sn114_yeast(display_long)|uniprotkb:GIN10(gene name synonym)|uniprotkb:YKL173W(locus name)|uniprotkb:YKL637(orf name)|uniprotkb:SNU114(gene name)|psi-mi:SNU114(display_short)|uniprotkb:Growth inhibitory protein 10(gene name synonym)|uniprotkb:114 kDa U5 small nuclear ribonucleoprotein component(gene name synonym) psi-mi:utp20_yeast(display_long)|uniprotkb:YBL004W(locus name)|uniprotkb:YBL0101(orf name)|uniprotkb:UTP20(gene name)|psi-mi:UTP20(display_short)|uniprotkb:U three protein 20(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326033|imex:IM-14275-1102 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012748.1|sgd:S000001656|mint:P36048|dip:DIP-759N|ensemblfungi:YKL173W(gene)|ensemblfungi:YKL173W_mRNA(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031950|interpro:IPR035647|interpro:IPR035655|interpro:IPR044121|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6TEO refseq:NP_009551.2|sgd:S000000100|dip:DIP-2826N|mint:P35194|ensemblfungi:YBL004W(gene)|ensemblfungi:YBL004W_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0032040"(small-subunit processome)|interpro:IPR011430(Down-regulated in metastasis)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:5CE30CEFF154D013 crc64:F6ED4E3E9AE0F468 figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:eHDUPadk87+Qb525xpL1tMWb3S4559292 rogid:jHfpz76nt2tQEEWYeM1PJlP4G8Q559292 intact-crc:4AAD1C74373AB792|rigid:Jhql9L62gRDmKojE6s3ZfWQ3rnM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36048 uniprotkb:P53874 intact:EBI-243|uniprotkb:D6VX27|ensemblfungi:YKL173W intact:EBI-19873|uniprotkb:D6W101|ensemblfungi:YNL186W psi-mi:sn114_yeast(display_long)|uniprotkb:GIN10(gene name synonym)|uniprotkb:YKL173W(locus name)|uniprotkb:YKL637(orf name)|uniprotkb:SNU114(gene name)|psi-mi:SNU114(display_short)|uniprotkb:Growth inhibitory protein 10(gene name synonym)|uniprotkb:114 kDa U5 small nuclear ribonucleoprotein component(gene name synonym) psi-mi:ubp10_yeast(display_long)|uniprotkb:UBP10(gene name)|psi-mi:UBP10(display_short)|uniprotkb:YNL186W(locus name)|uniprotkb:N1619(orf name)|uniprotkb:Ubiquitin-specific-processing protease 10(gene name synonym)|uniprotkb:Deubiquitinating enzyme 10(gene name synonym)|uniprotkb:Disrupter of telomere silencing protein 4(gene name synonym)|uniprotkb:Ubiquitin thioesterase 10(gene name synonym)|uniprotkb:DOT4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326044|imex:IM-14275-1103 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012748.1|sgd:S000001656|mint:P36048|dip:DIP-759N|ensemblfungi:YKL173W(gene)|ensemblfungi:YKL173W_mRNA(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031950|interpro:IPR035647|interpro:IPR035655|interpro:IPR044121|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6TEO refseq:NP_014213.2|sgd:S000005130|ensemblfungi:YNL186W(gene)|ensemblfungi:YNL186W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0043596"(nuclear replication fork)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|rcsb pdb:6RR0|dip:DIP-6664N|mint:P53874 psi-mi:"MI:0469"(intact) crc64:5CE30CEFF154D013 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:eHDUPadk87+Qb525xpL1tMWb3S4559292 rogid:Z1rRAI9RLgHeGd7QwLbrf51v5LY559292 intact-crc:790AB67212F7FF53|rigid:PFwB4M1NMijeMgZ41dqEi3QQg4M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12339 uniprotkb:P36048 intact:EBI-30231|uniprotkb:D6W270|ensemblfungi:YOR004W intact:EBI-243|uniprotkb:D6VX27|ensemblfungi:YKL173W psi-mi:utp23_yeast(display_long)|uniprotkb:U3 small nucleolar RNA-associated protein 23(gene name synonym)|uniprotkb:U three protein 23(gene name synonym)|uniprotkb:UTP23(gene name)|psi-mi:UTP23(display_short)|uniprotkb:YOR004W(locus name) psi-mi:sn114_yeast(display_long)|uniprotkb:GIN10(gene name synonym)|uniprotkb:YKL173W(locus name)|uniprotkb:YKL637(orf name)|uniprotkb:SNU114(gene name)|psi-mi:SNU114(display_short)|uniprotkb:Growth inhibitory protein 10(gene name synonym)|uniprotkb:114 kDa U5 small nuclear ribonucleoprotein component(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326055|imex:IM-14275-1104 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014646.1|sgd:S000005530|dip:DIP-4352N|mint:Q12339|ensemblfungi:YOR004W(gene)|ensemblfungi:YOR004W_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0032040"(small-subunit processome)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR006984(Protein of unknown function DUF652)|interpro:IPR029060|rcsb pdb:4MJ7 refseq:NP_012748.1|sgd:S000001656|mint:P36048|dip:DIP-759N|ensemblfungi:YKL173W(gene)|ensemblfungi:YKL173W_mRNA(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031950|interpro:IPR035647|interpro:IPR035655|interpro:IPR044121|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6TEO psi-mi:"MI:0469"(intact) crc64:27D00C72F6B492F6 crc64:5CE30CEFF154D013 figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:OvURSlkfCuWUay/vbYqayjai9/A559292 rogid:eHDUPadk87+Qb525xpL1tMWb3S4559292 intact-crc:A00B1667C4BC0982|rigid:LDkgHirx9Sq62XbzIiqStKJgas4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21304 uniprotkb:P36049 intact:EBI-14328|uniprotkb:D6VYJ9|ensemblfungi:YLR196W intact:EBI-6289|uniprotkb:D6VX28|ensemblfungi:YKL172W psi-mi:pwp1_yeast(display_long)|uniprotkb:L8167.10(orf name)|uniprotkb:YLR196W(locus name)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short) psi-mi:ebp2_yeast(display_long)|uniprotkb:EBP2(gene name)|psi-mi:EBP2(display_short)|uniprotkb:YKL172W(locus name)|uniprotkb:YKL636(orf name)|uniprotkb:EBNA1-binding protein homolog(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326067|imex:IM-14275-1105 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013297.1|sgd:S000004186|ensemblfungi:YLR196W(gene)|ensemblfungi:YLR196W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR044285|mint:P21304|dip:DIP-4203N refseq:NP_012749.1|sgd:S000001655|dip:DIP-6507N|mint:P36049|ensemblfungi:YKL172W(gene)|ensemblfungi:YKL172W_mRNA(transcript)|go:"GO:0000280"(nuclear division)|go:"GO:0003729"(mRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|interpro:IPR008610(Eukaryotic rRNA processing)|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:FC0189B289494AB5 crc64:4A11F6CDF779DB5A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Q1nPXtlkpIw8JosaiYX0PSVNaSw559292 rogid:REBsvnJsdQ5YZAYierE0DT1mCx4559292 intact-crc:F4E742295321349E|rigid:RBZg8VBI+mMPC3COZWkPYwNv2zE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36049 uniprotkb:P24783 intact:EBI-6289|uniprotkb:D6VX28|ensemblfungi:YKL172W intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W psi-mi:ebp2_yeast(display_long)|uniprotkb:EBP2(gene name)|psi-mi:EBP2(display_short)|uniprotkb:YKL172W(locus name)|uniprotkb:YKL636(orf name)|uniprotkb:EBNA1-binding protein homolog(gene name synonym) psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326078|imex:IM-14275-1106 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012749.1|sgd:S000001655|dip:DIP-6507N|mint:P36049|ensemblfungi:YKL172W(gene)|ensemblfungi:YKL172W_mRNA(transcript)|go:"GO:0000280"(nuclear division)|go:"GO:0003729"(mRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|interpro:IPR008610(Eukaryotic rRNA processing)|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|reactome:R-SCE-6791226 sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) crc64:4A11F6CDF779DB5A crc64:30FE3D4C7E653120 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:REBsvnJsdQ5YZAYierE0DT1mCx4559292 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 intact-crc:795794D344B4D23C|rigid:p3CJgcBCN31FF0QsoKtcBnt2SUw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36049 uniprotkb:P32495 intact:EBI-6289|uniprotkb:D6VX28|ensemblfungi:YKL172W intact:EBI-12014|ensemblfungi:YDL208W|uniprotkb:D6VRE6 psi-mi:ebp2_yeast(display_long)|uniprotkb:EBP2(gene name)|psi-mi:EBP2(display_short)|uniprotkb:YKL172W(locus name)|uniprotkb:YKL636(orf name)|uniprotkb:EBNA1-binding protein homolog(gene name synonym) psi-mi:nhp2_yeast(display_long)|uniprotkb:NHP2(gene name)|psi-mi:NHP2(display_short)|uniprotkb:YDL208W(locus name)|uniprotkb:D1045(orf name)|uniprotkb:H/ACA snoRNP protein NHP2(gene name synonym)|uniprotkb:High mobility group-like nuclear protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326089|imex:IM-14275-1107 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012749.1|sgd:S000001655|dip:DIP-6507N|mint:P36049|ensemblfungi:YKL172W(gene)|ensemblfungi:YKL172W_mRNA(transcript)|go:"GO:0000280"(nuclear division)|go:"GO:0003729"(mRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|interpro:IPR008610(Eukaryotic rRNA processing)|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|reactome:R-SCE-6791226 ensemblfungi:YDL208W(gene)|ensemblfungi:YDL208W_mRNA(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000493"(box H/ACA snoRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|rcsb pdb:2LBW|rcsb pdb:2LBX|refseq:NP_010073.2|sgd:S000002367|mint:P32495|dip:DIP-5134N psi-mi:"MI:0469"(intact) crc64:4A11F6CDF779DB5A crc64:008188132B494E5D figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:REBsvnJsdQ5YZAYierE0DT1mCx4559292 rogid:p5AQTuMF3Vvdu6HWSTYjdjjE1Vs559292 intact-crc:10B12901AE112629|rigid:n5OhtaYLYP8045SrppYYE5QHQeU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36049 uniprotkb:P37838 intact:EBI-6289|uniprotkb:D6VX28|ensemblfungi:YKL172W intact:EBI-12122|uniprotkb:D6W3X0|ensemblfungi:YPL043W psi-mi:ebp2_yeast(display_long)|uniprotkb:EBP2(gene name)|psi-mi:EBP2(display_short)|uniprotkb:YKL172W(locus name)|uniprotkb:YKL636(orf name)|uniprotkb:EBNA1-binding protein homolog(gene name synonym) psi-mi:nop4_yeast(display_long)|uniprotkb:YPL043W(locus name)|uniprotkb:Nucleolar protein NOP77(gene name synonym)|uniprotkb:NOP4(gene name)|psi-mi:NOP4(display_short)|uniprotkb:NOP77(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326100|imex:IM-14275-1108 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012749.1|sgd:S000001655|dip:DIP-6507N|mint:P36049|ensemblfungi:YKL172W(gene)|ensemblfungi:YKL172W_mRNA(transcript)|go:"GO:0000280"(nuclear division)|go:"GO:0003729"(mRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|interpro:IPR008610(Eukaryotic rRNA processing)|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|reactome:R-SCE-6791226 ensemblfungi:YPL043W(gene)|ensemblfungi:YPL043W_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034806|interpro:IPR034808|interpro:IPR034809|interpro:IPR035979|refseq:NP_015282.1|sgd:S000005964|dip:DIP-3891N|mint:P37838 psi-mi:"MI:0469"(intact) crc64:4A11F6CDF779DB5A crc64:61261815EA3DEE5C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:REBsvnJsdQ5YZAYierE0DT1mCx4559292 rogid:R77UUAa8AF0k70aGHQ+MiwWZX3U559292 intact-crc:44C4E16AAAD09FDF|rigid:2CUP9pxefBn3T48d7UU73R8mm3k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38202 uniprotkb:P36049 intact:EBI-2054775|uniprotkb:D6VPX2|ensemblfungi:YBL028C intact:EBI-6289|uniprotkb:D6VX28|ensemblfungi:YKL172W psi-mi:ybc8_yeast(display_long)|uniprotkb:YBL0423(orf name)|uniprotkb:YBL028C(locus name) psi-mi:ebp2_yeast(display_long)|uniprotkb:EBP2(gene name)|psi-mi:EBP2(display_short)|uniprotkb:YKL172W(locus name)|uniprotkb:YKL636(orf name)|uniprotkb:EBNA1-binding protein homolog(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326111|imex:IM-14275-1109 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009525.1|sgd:S000000124|interpro:IPR019434|mint:P38202|ensemblfungi:YBL028C(gene)|ensemblfungi:YBL028C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|rcsb pdb:3JCT|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:6N8K|rcsb pdb:6N8L|rcsb pdb:6YLG|rcsb pdb:6YLH|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BT6|rcsb pdb:7BTB refseq:NP_012749.1|sgd:S000001655|dip:DIP-6507N|mint:P36049|ensemblfungi:YKL172W(gene)|ensemblfungi:YKL172W_mRNA(transcript)|go:"GO:0000280"(nuclear division)|go:"GO:0003729"(mRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|interpro:IPR008610(Eukaryotic rRNA processing)|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) - crc64:4A11F6CDF779DB5A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tXi28WJQJdjv3sXE1kc8Vd7xdt8559292 rogid:REBsvnJsdQ5YZAYierE0DT1mCx4559292 intact-crc:82701BD30CE16AAF|rigid:TWngKAiyiobTk0I3zdBjFZOwNE8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39744 uniprotkb:P36049 intact:EBI-29259|uniprotkb:Q08625|uniprotkb:D6W2R2|ensemblfungi:YOR206W intact:EBI-6289|uniprotkb:D6VX28|ensemblfungi:YKL172W psi-mi:noc2_yeast(display_long)|uniprotkb:YOX001(orf name)|uniprotkb:YOR206W(locus name)|uniprotkb:NOC2(gene name)|psi-mi:NOC2(display_short) psi-mi:ebp2_yeast(display_long)|uniprotkb:EBP2(gene name)|psi-mi:EBP2(display_short)|uniprotkb:YKL172W(locus name)|uniprotkb:YKL636(orf name)|uniprotkb:EBNA1-binding protein homolog(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326122|imex:IM-14275-1110 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014849.3|sgd:S000005732|dip:DIP-4559N|mint:P39744|ensemblfungi:YOR206W(gene)|ensemblfungi:YOR206W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR005343(Protein of unknown function UPF0120) refseq:NP_012749.1|sgd:S000001655|dip:DIP-6507N|mint:P36049|ensemblfungi:YKL172W(gene)|ensemblfungi:YKL172W_mRNA(transcript)|go:"GO:0000280"(nuclear division)|go:"GO:0003729"(mRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|interpro:IPR008610(Eukaryotic rRNA processing)|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:48C3B9AE076B9B8F crc64:4A11F6CDF779DB5A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:d5I8KJOSG63bZ/Pt+XvKdy/SWws559292 rogid:REBsvnJsdQ5YZAYierE0DT1mCx4559292 intact-crc:7B33B529D6FAEA2C|rigid:1g/qiRfXAaZ765aIicpq371uUdY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40078 uniprotkb:P36049 intact:EBI-22681|uniprotkb:D3DM32|ensemblfungi:YER126C intact:EBI-6289|uniprotkb:D6VX28|ensemblfungi:YKL172W psi-mi:nsa2_yeast(display_long)|uniprotkb:YER126C(locus name)|uniprotkb:SYGP-ORF47(orf name)|uniprotkb:NSA2(gene name)|psi-mi:NSA2(display_short)|uniprotkb:NOP7-associated protein 2(gene name synonym) psi-mi:ebp2_yeast(display_long)|uniprotkb:EBP2(gene name)|psi-mi:EBP2(display_short)|uniprotkb:YKL172W(locus name)|uniprotkb:YKL636(orf name)|uniprotkb:EBNA1-binding protein homolog(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326133|imex:IM-14275-1111 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011052.1|sgd:S000000928|dip:DIP-1892N|mint:P40078|ensemblfungi:YER126C(gene)|ensemblfungi:YER126C_mRNA(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR022309|interpro:IPR039411|rcsb pdb:3JCT|rcsb pdb:4WJV|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:7BT6|rcsb pdb:7BTB refseq:NP_012749.1|sgd:S000001655|dip:DIP-6507N|mint:P36049|ensemblfungi:YKL172W(gene)|ensemblfungi:YKL172W_mRNA(transcript)|go:"GO:0000280"(nuclear division)|go:"GO:0003729"(mRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|interpro:IPR008610(Eukaryotic rRNA processing)|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:545C8B4250BCB0C9 crc64:4A11F6CDF779DB5A figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ru6dofBbaVkHM+0tunQ4n36y98M559292 rogid:REBsvnJsdQ5YZAYierE0DT1mCx4559292 intact-crc:8080A5D6D248A20F|rigid:+b0rpLOvF5AegRC7lhkMP3yX3K8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36049 uniprotkb:P40693 intact:EBI-6289|uniprotkb:D6VX28|ensemblfungi:YKL172W intact:EBI-15415|uniprotkb:D6W1H5|ensemblfungi:YNL002C psi-mi:ebp2_yeast(display_long)|uniprotkb:EBP2(gene name)|psi-mi:EBP2(display_short)|uniprotkb:YKL172W(locus name)|uniprotkb:YKL636(orf name)|uniprotkb:EBNA1-binding protein homolog(gene name synonym) psi-mi:rlp7_yeast(display_long)|uniprotkb:RPL7(gene name synonym)|uniprotkb:N2014(orf name)|uniprotkb:YNL002C(locus name)|uniprotkb:RLP7(gene name)|psi-mi:RLP7(display_short)|uniprotkb:Ribosomal protein L7-like(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326144|imex:IM-14275-1112 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012749.1|sgd:S000001655|dip:DIP-6507N|mint:P36049|ensemblfungi:YKL172W(gene)|ensemblfungi:YKL172W_mRNA(transcript)|go:"GO:0000280"(nuclear division)|go:"GO:0003729"(mRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|interpro:IPR008610(Eukaryotic rRNA processing)|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|reactome:R-SCE-6791226 sgd:S000004947|refseq:NP_014396.3|ensemblfungi:YNL002C(gene)|ensemblfungi:YNL002C_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000465"("exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|rcsb pdb:3JCT|rcsb pdb:4V7F|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6M62|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BTB|dip:DIP-6476N|mint:P40693 psi-mi:"MI:0469"(intact) crc64:4A11F6CDF779DB5A crc64:64714DDFAFB90B5D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:REBsvnJsdQ5YZAYierE0DT1mCx4559292 rogid:HR8kGX5foVbBQ/nWTKMM16uB3E8559292 intact-crc:B35AA90844F1F55B|rigid:ieX70jUVpU6OEQ3ISC96bmT9sCY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43586 uniprotkb:P36049 intact:EBI-22906|uniprotkb:D6VTN1|ensemblfungi:YFR001W intact:EBI-6289|uniprotkb:D6VX28|ensemblfungi:YKL172W psi-mi:loc1_yeast(display_long)|uniprotkb:YFR001W(locus name)|uniprotkb:LOC1(gene name)|psi-mi:LOC1(display_short)|uniprotkb:Localization of ASH1 mRNA protein 1(gene name synonym) psi-mi:ebp2_yeast(display_long)|uniprotkb:EBP2(gene name)|psi-mi:EBP2(display_short)|uniprotkb:YKL172W(locus name)|uniprotkb:YKL636(orf name)|uniprotkb:EBNA1-binding protein homolog(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326155|imex:IM-14275-1113 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116656.1|sgd:S000001897|dip:DIP-6615N|mint:P43586|ensemblfungi:YFR001W(gene)|ensemblfungi:YFR001W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051028"(mRNA transport)|go:"GO:0101031"(chaperone complex)|interpro:IPR037650|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)") refseq:NP_012749.1|sgd:S000001655|dip:DIP-6507N|mint:P36049|ensemblfungi:YKL172W(gene)|ensemblfungi:YKL172W_mRNA(transcript)|go:"GO:0000280"(nuclear division)|go:"GO:0003729"(mRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|interpro:IPR008610(Eukaryotic rRNA processing)|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:69970294E9C980F9 crc64:4A11F6CDF779DB5A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9z0K05pOV8o7bqozFWieGjfs/FM559292 rogid:REBsvnJsdQ5YZAYierE0DT1mCx4559292 intact-crc:626A249606862270|rigid:vz/dP5wngEefUWWeW88OIvZp0CI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36049 uniprotkb:P53188 intact:EBI-6289|uniprotkb:D6VX28|ensemblfungi:YKL172W intact:EBI-23731|uniprotkb:D6VUA9|ensemblfungi:YGL029W psi-mi:ebp2_yeast(display_long)|uniprotkb:EBP2(gene name)|psi-mi:EBP2(display_short)|uniprotkb:YKL172W(locus name)|uniprotkb:YKL636(orf name)|uniprotkb:EBNA1-binding protein homolog(gene name synonym) psi-mi:cgr1_yeast(display_long)|uniprotkb:YGL029W(locus name)|uniprotkb:CGR1(gene name)|psi-mi:CGR1(display_short)|uniprotkb:Coiled-coil growth-regulated protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326166|imex:IM-14275-1114 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012749.1|sgd:S000001655|dip:DIP-6507N|mint:P36049|ensemblfungi:YKL172W(gene)|ensemblfungi:YKL172W_mRNA(transcript)|go:"GO:0000280"(nuclear division)|go:"GO:0003729"(mRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|interpro:IPR008610(Eukaryotic rRNA processing)|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|reactome:R-SCE-6791226 refseq:NP_011486.1|sgd:S000002997|dip:DIP-5450N|mint:P53188|ensemblfungi:YGL029W(gene)|ensemblfungi:YGL029W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR005579(Cgr1)|rcsb pdb:3JCT|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6YLG|rcsb pdb:6YLH psi-mi:"MI:0469"(intact) crc64:4A11F6CDF779DB5A - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:REBsvnJsdQ5YZAYierE0DT1mCx4559292 rogid:G7SUf9/XRWXFaYG1LRPoChi6BVA559292 intact-crc:D29E86C6863C89DA|rigid:BYVuPqV1HIoE6vHr0F1Q0S1tCGE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36049 uniprotkb:P53849 intact:EBI-6289|uniprotkb:D6VX28|ensemblfungi:YKL172W intact:EBI-29244|uniprotkb:D6W0T8|ensemblfungi:YNL255C psi-mi:ebp2_yeast(display_long)|uniprotkb:EBP2(gene name)|psi-mi:EBP2(display_short)|uniprotkb:YKL172W(locus name)|uniprotkb:YKL636(orf name)|uniprotkb:EBNA1-binding protein homolog(gene name synonym) psi-mi:gis2_yeast(display_long)|uniprotkb:GIS2(gene name)|psi-mi:GIS2(display_short)|uniprotkb:N0852(orf name)|uniprotkb:YNL255C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326177|imex:IM-14275-1115 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012749.1|sgd:S000001655|dip:DIP-6507N|mint:P36049|ensemblfungi:YKL172W(gene)|ensemblfungi:YKL172W_mRNA(transcript)|go:"GO:0000280"(nuclear division)|go:"GO:0003729"(mRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|interpro:IPR008610(Eukaryotic rRNA processing)|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|reactome:R-SCE-6791226 refseq:NP_014144.1|sgd:S000005199|dip:DIP-2669N|mint:P53849|ensemblfungi:YNL255C(gene)|ensemblfungi:YNL255C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045182"(translation regulator activity)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875 psi-mi:"MI:0469"(intact) crc64:4A11F6CDF779DB5A crc64:E72696428F85CA3F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:REBsvnJsdQ5YZAYierE0DT1mCx4559292 rogid:kftHFJVi7QRZASmr4hLdALvleR4559292 intact-crc:377F03E45867AE53|rigid:lwjrpT/aTuUTt/gtvTe6RM87+GM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08235 uniprotkb:P36049 intact:EBI-3775|uniprotkb:D6W1Z1|ensemblfungi:YOL077C intact:EBI-6289|uniprotkb:D6VX28|ensemblfungi:YKL172W psi-mi:brx1_yeast(display_long)|uniprotkb:YOL077C(locus name)|uniprotkb:BRX1(gene name)|psi-mi:BRX1(display_short) psi-mi:ebp2_yeast(display_long)|uniprotkb:EBP2(gene name)|psi-mi:EBP2(display_short)|uniprotkb:YKL172W(locus name)|uniprotkb:YKL636(orf name)|uniprotkb:EBNA1-binding protein homolog(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326188|imex:IM-14275-1116 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014565.2|sgd:S000005437|dip:DIP-6317N|mint:Q08235|ensemblfungi:YOL077C(gene)|ensemblfungi:YOL077C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000464"("endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000465"("exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR007109(Brix)|interpro:IPR026532|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5 refseq:NP_012749.1|sgd:S000001655|dip:DIP-6507N|mint:P36049|ensemblfungi:YKL172W(gene)|ensemblfungi:YKL172W_mRNA(transcript)|go:"GO:0000280"(nuclear division)|go:"GO:0003729"(mRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|interpro:IPR008610(Eukaryotic rRNA processing)|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:31466853EF0E7301 crc64:4A11F6CDF779DB5A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mPR6HWKwM6RNCRE/vezsYlCmEGY559292 rogid:REBsvnJsdQ5YZAYierE0DT1mCx4559292 intact-crc:CE1ECF702ED64982|rigid:IjgWqBz40YKdLTvgFGdmIx4pZ3c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36049 uniprotkb:Q08746 intact:EBI-6289|uniprotkb:D6VX28|ensemblfungi:YKL172W intact:EBI-16026|uniprotkb:D6W2Z3|ensemblfungi:YOR294W psi-mi:ebp2_yeast(display_long)|uniprotkb:EBP2(gene name)|psi-mi:EBP2(display_short)|uniprotkb:YKL172W(locus name)|uniprotkb:YKL636(orf name)|uniprotkb:EBNA1-binding protein homolog(gene name synonym) psi-mi:rrs1_yeast(display_long)|uniprotkb:RRS1(gene name)|psi-mi:RRS1(display_short)|uniprotkb:YOR294W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326199|imex:IM-14275-1117 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012749.1|sgd:S000001655|dip:DIP-6507N|mint:P36049|ensemblfungi:YKL172W(gene)|ensemblfungi:YKL172W_mRNA(transcript)|go:"GO:0000280"(nuclear division)|go:"GO:0003729"(mRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|interpro:IPR008610(Eukaryotic rRNA processing)|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|reactome:R-SCE-6791226 ensemblfungi:YOR294W(gene)|refseq:NP_014937.1|sgd:S000005820|ensemblfungi:YOR294W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR007023(Ribosomal biogenesis regulatory protein)|rcsb pdb:3JCT|rcsb pdb:5A53|rcsb pdb:5WXL|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:7BT6|rcsb pdb:7BTB|dip:DIP-4081N|mint:Q08746 psi-mi:"MI:0469"(intact) crc64:4A11F6CDF779DB5A crc64:7DFF6C51DDD2ADD6 figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:REBsvnJsdQ5YZAYierE0DT1mCx4559292 rogid:JyvCj+ru9yzw4WAhTwy+V5dUdxY559292 intact-crc:0A5BC9D6943DD4C1|rigid:gACwaNvvCQPXCTDv+T1iiJXa0qk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12176 uniprotkb:P36049 intact:EBI-10944|ensemblfungi:YDR060W|uniprotkb:D6VS46 intact:EBI-6289|uniprotkb:D6VX28|ensemblfungi:YKL172W psi-mi:mak21_yeast(display_long)|uniprotkb:MAK21(gene name)|psi-mi:MAK21(display_short)|uniprotkb:YDR060W(locus name)|uniprotkb:D4237(orf name)|uniprotkb:YD9609.14(orf name)|uniprotkb:NOC1(gene name synonym)|uniprotkb:Maintenance of killer protein 21(gene name synonym)|uniprotkb:Nucleolar complex protein 1(gene name synonym) psi-mi:ebp2_yeast(display_long)|uniprotkb:EBP2(gene name)|psi-mi:EBP2(display_short)|uniprotkb:YKL172W(locus name)|uniprotkb:YKL636(orf name)|uniprotkb:EBNA1-binding protein homolog(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326211|imex:IM-14275-1118 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR060W(gene)|ensemblfungi:YDR060W_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|interpro:IPR005612(CBF)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040155|sgd:S000002467|refseq:NP_010345.3|mint:Q12176|dip:DIP-4040N refseq:NP_012749.1|sgd:S000001655|dip:DIP-6507N|mint:P36049|ensemblfungi:YKL172W(gene)|ensemblfungi:YKL172W_mRNA(transcript)|go:"GO:0000280"(nuclear division)|go:"GO:0003729"(mRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|interpro:IPR008610(Eukaryotic rRNA processing)|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) - crc64:4A11F6CDF779DB5A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Y5IkqRgw551Db48w/pnXZm0AtvQ559292 rogid:REBsvnJsdQ5YZAYierE0DT1mCx4559292 intact-crc:793341EE20C16258|rigid:OkfXr5vauZ3nKRf4tSYiR1bKPzU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12754 uniprotkb:P36049 intact:EBI-30678|uniprotkb:Q7LH12|uniprotkb:D6W400|ensemblfungi:YPL012W intact:EBI-6289|uniprotkb:D6VX28|ensemblfungi:YKL172W psi-mi:rrp12_yeast(display_long)|uniprotkb:RRP12(gene name)|psi-mi:RRP12(display_short)|uniprotkb:YPL012W(locus name) psi-mi:ebp2_yeast(display_long)|uniprotkb:EBP2(gene name)|psi-mi:EBP2(display_short)|uniprotkb:YKL172W(locus name)|uniprotkb:YKL636(orf name)|uniprotkb:EBNA1-binding protein homolog(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326222|imex:IM-14275-1119 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015313.1|sgd:S000005933|dip:DIP-6497N|mint:Q12754|ensemblfungi:YPL012W(gene)|ensemblfungi:YPL012W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012978(Region of unknown function, NUC173)|interpro:IPR016024(Armadillo-type fold) refseq:NP_012749.1|sgd:S000001655|dip:DIP-6507N|mint:P36049|ensemblfungi:YKL172W(gene)|ensemblfungi:YKL172W_mRNA(transcript)|go:"GO:0000280"(nuclear division)|go:"GO:0003729"(mRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|interpro:IPR008610(Eukaryotic rRNA processing)|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:92333BCD53CB095F crc64:4A11F6CDF779DB5A figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RP53JIWBThgT+cJh8AQgdOresC8559292 rogid:REBsvnJsdQ5YZAYierE0DT1mCx4559292 intact-crc:A71467421DB6EA74|rigid:pwi45J88SouS3G/dYnB89i2FoKk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36051 uniprotkb:P54837 intact:EBI-2070979|uniprotkb:D6VX34|ensemblfungi:YKL165C intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:mcd4_yeast(display_long)|uniprotkb:MCD4(gene name)|psi-mi:MCD4(display_short)|uniprotkb:FSR2(gene name synonym)|uniprotkb:SSU21(gene name synonym)|uniprotkb:ZRG16(gene name synonym)|uniprotkb:Morphogenesis checkpoint-dependent protein 4(gene name synonym)|uniprotkb:Supersecretion of u-PA protein 21(gene name synonym)|uniprotkb:YKL619(orf name)|uniprotkb:YKL165C(locus name) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326233|imex:IM-14275-1120 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012756.1|sgd:S000001648|dip:DIP-8272N|mint:P36051|ensemblfungi:YKL165C(gene)|ensemblfungi:YKL165C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008484"(sulfuric ester hydrolase activity)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0015867"(ATP transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051377"(mannose-ethanolamine phosphotransferase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR000917(Sulphatase)|interpro:IPR007070(GPI ethanolamine phosphate transferase 1)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR017852(GPI ethanolamine phosphate transferase 1, C-terminal)|interpro:IPR037671|reactome:R-SCE-162710 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:P11dczTg1VFiAz9e0ph+HvPvSQQ559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:C4E2F98B99451DE4|rigid:YdRf7+nVLpl8yc7p6zuyJGmanO4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25296 uniprotkb:P36054 intact:EBI-3968|uniprotkb:D6VX10|ensemblfungi:YKL190W intact:EBI-14898|ensemblfungi:YKL159C|uniprotkb:D6VX40 psi-mi:canb_yeast(display_long)|uniprotkb:CNB1(gene name)|psi-mi:CNB1(display_short)|uniprotkb:YCN2(gene name synonym)|uniprotkb:YCNB(gene name synonym)|uniprotkb:Protein phosphatase 2B regulatory subunit(gene name synonym)|uniprotkb:Calcineurin regulatory subunit(gene name synonym)|uniprotkb:YKL190W(locus name) psi-mi:rcn1_yeast(display_long)|uniprotkb:RCN1(gene name)|psi-mi:RCN1(display_short)|uniprotkb:YKL159C(locus name)|uniprotkb:YKL613(orf name)|uniprotkb:DSCR1L(gene name synonym)|uniprotkb:Regulator of calcineurin 1(gene name synonym)|uniprotkb:Down syndrome candidate region 1-like protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326244|imex:IM-14275-1121 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012731.1|sgd:S000001673|dip:DIP-510N|mint:P25296|ensemblfungi:YKL190W(gene)|ensemblfungi:YKL190W_mRNA(transcript)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006873"(cellular ion homeostasis)|go:"GO:0008597"(calcium-dependent protein serine/threonine phosphatase regulator activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015757(Calcineurin B protein)|interpro:IPR018247|reactome:R-SCE-2871809|reactome:R-SCE-4086398|reactome:R-SCE-5607763 ensemblfungi:YKL159C(gene)|ensemblfungi:YKL159C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008597"(calcium-dependent protein serine/threonine phosphatase regulator activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030346"(protein phosphatase 2B binding)|interpro:IPR006931(Calcipressin)|interpro:IPR016523(Uncharacterised conserved protein UCP007798)|refseq:NP_012763.1|sgd:S000001642|dip:DIP-7429N|mint:P36054 psi-mi:"MI:0469"(intact) crc64:6E42DB350DA05BC0 crc64:668EA0C10D4E39AA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:eow/RCumgmpTh5Kfe66TOem5Sp0559292 rogid:S+Wq+Nvw1+vOsw67ubkq+Gmesco559292 intact-crc:66505920B3223F32|rigid:bTHMHgHUApZZRJTeZh1IbyDzaSU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36060 uniprotkb:P54783 intact:EBI-10565|uniprotkb:A2TBM9|ensemblfungi:YKL150W|uniprotkb:D6VX47 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:mcr1_yeast(display_long)|uniprotkb:MCR1(gene name)|psi-mi:MCR1(display_short)|uniprotkb:YKL150W(locus name)|uniprotkb:YKL605(orf name)|uniprotkb:Mitochondrial cytochrome b reductase(gene name synonym)|uniprotkb:p34/p32(gene name synonym) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326255|imex:IM-14275-1122 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YKL150W(gene)|ensemblfungi:YKL150W_mRNA(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR017927|interpro:IPR017938|interpro:IPR039261|go:"GO:0005741"(mitochondrial outer membrane)|refseq:NP_012772.1|sgd:S000001633|mint:P36060|dip:DIP-5475N go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) crc64:D3CB56356E8C572F - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cZZmB8fsXBHqVojDE6ZoXzjsyLI559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:F58936D48DA81E22|rigid:8qbFJzCENI5AmYmRscMLgCpOJhc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P36076 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326266|imex:IM-14275-1123 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:Li7vZOassm4PC5fW111/j5ivgEc559292 intact-crc:33EBE8A7488B74C2|rigid:eZ7trzF9IOI0Pw8Yl8Oli0oXBn0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36076 uniprotkb:P26570 intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short) psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326277|imex:IM-14275-1124 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783 ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N psi-mi:"MI:0469"(intact) - crc64:8B7F009521F72C15 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Li7vZOassm4PC5fW111/j5ivgEc559292 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 intact-crc:AB5C2BC205EFDC93|rigid:dgCALvIJ7I7h3RD+Hxf37fYBTl8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36076 uniprotkb:P33329 intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W intact:EBI-13815|ensemblfungi:YDR436W|uniprotkb:D6VT63 psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short) psi-mi:ppz2_yeast(display_long)|uniprotkb:PPZ2(gene name)|psi-mi:PPZ2(display_short)|uniprotkb:D9461.22(orf name)|uniprotkb:YDR436W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326288|imex:IM-14275-1125 author score:96.38 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783 ensemblfungi:YDR436W(gene)|ensemblfungi:YDR436W_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0046872"(metal ion binding)|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|go:"GO:0106306"|refseq:NP_010724.1|sgd:S000002844|mint:P33329|dip:DIP-6355N psi-mi:"MI:0469"(intact) - crc64:3095F37046489AFB figure legend:tables S3 and S4|author-confidence:96.38|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Li7vZOassm4PC5fW111/j5ivgEc559292 rogid:WpYxSWimbMNz9ZdZHpezPp/B2Sc559292 intact-crc:836F43392D998061|rigid:hSKf1FEveSwJ/k0en0pHN/aMCe4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36076 uniprotkb:P36024 intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short) psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326299|imex:IM-14275-1126 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783 refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Li7vZOassm4PC5fW111/j5ivgEc559292 rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292 intact-crc:A756303F87576AF9|rigid:w+Dyw0kudYkd6B6rHxz3iztH/AA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36076 uniprotkb:Q08438 intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short) psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326310|imex:IM-14275-1127 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783 refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551 psi-mi:"MI:0469"(intact) - crc64:A97623473CB6F605 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Li7vZOassm4PC5fW111/j5ivgEc559292 rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292 intact-crc:1FCF70535DE2C16D|rigid:g8JD/Rsz9EvbVR6Upimp3T8UhJQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36095 uniprotkb:P36095 intact:EBI-26653|uniprotkb:D6VXP5|ensemblfungi:YKL041W intact:EBI-26653|uniprotkb:D6VXP5|ensemblfungi:YKL041W psi-mi:vps24_yeast(display_long)|uniprotkb:YKL041W(locus name)|uniprotkb:YKL254(orf name)|uniprotkb:VPS24(gene name)|psi-mi:VPS24(display_short)|uniprotkb:DID3(gene name synonym)|uniprotkb:DOA4-independent degradation protein 3(gene name synonym)|uniprotkb:ESCRT-III complex subunit VPS24(gene name synonym) psi-mi:vps24_yeast(display_long)|uniprotkb:YKL041W(locus name)|uniprotkb:YKL254(orf name)|uniprotkb:VPS24(gene name)|psi-mi:VPS24(display_short)|uniprotkb:DID3(gene name synonym)|uniprotkb:DOA4-independent degradation protein 3(gene name synonym)|uniprotkb:ESCRT-III complex subunit VPS24(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326321|imex:IM-14275-1128 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012883.1|sgd:S000001524|mint:P36095|dip:DIP-7295N|ensemblfungi:YKL041W(gene)|ensemblfungi:YKL041W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR005024(Snf7)|rcsb pdb:6ZH3|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328 refseq:NP_012883.1|sgd:S000001524|mint:P36095|dip:DIP-7295N|ensemblfungi:YKL041W(gene)|ensemblfungi:YKL041W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR005024(Snf7)|rcsb pdb:6ZH3|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328 psi-mi:"MI:0469"(intact) crc64:6073C1B680D58E98 crc64:6073C1B680D58E98 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mA7XIOAPTcq8iFqDtd5Uk4cdhD0559292 rogid:mA7XIOAPTcq8iFqDtd5Uk4cdhD0559292 intact-crc:E0CB890A8780F995|rigid:pLITuzcgG1OdpU504TRoWiyCyU4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39929 uniprotkb:P36095 intact:EBI-17554|uniprotkb:D6VY27|ensemblfungi:YLR025W|uniprotkb:E9P8V6 intact:EBI-26653|uniprotkb:D6VXP5|ensemblfungi:YKL041W psi-mi:snf7_yeast(display_long)|uniprotkb:SNF7(gene name)|psi-mi:SNF7(display_short)|uniprotkb:VPS32(gene name synonym)|uniprotkb:YLR025W(locus name)|uniprotkb:DID1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 32(gene name synonym)|uniprotkb:DOA4-independent degradation protein 1(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 7(gene name synonym) psi-mi:vps24_yeast(display_long)|uniprotkb:YKL041W(locus name)|uniprotkb:YKL254(orf name)|uniprotkb:VPS24(gene name)|psi-mi:VPS24(display_short)|uniprotkb:DID3(gene name synonym)|uniprotkb:DOA4-independent degradation protein 3(gene name synonym)|uniprotkb:ESCRT-III complex subunit VPS24(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326332|imex:IM-14275-1129 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013125.1|sgd:S000004015|ensemblfungi:YLR025W(gene)|ensemblfungi:YLR025W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0071454"(cellular response to anoxia)|go:"GO:1904669"(ATP export)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|rcsb pdb:5FD7|rcsb pdb:5FD9|rcsb pdb:5T8L|rcsb pdb:5T8N|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1747N|mint:P39929 refseq:NP_012883.1|sgd:S000001524|mint:P36095|dip:DIP-7295N|ensemblfungi:YKL041W(gene)|ensemblfungi:YKL041W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR005024(Snf7)|rcsb pdb:6ZH3|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328 psi-mi:"MI:0469"(intact) crc64:5241A18BB181F0C1 crc64:6073C1B680D58E98 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I8qBtNlqTjxLX1HginTOzM3o9oA559292 rogid:mA7XIOAPTcq8iFqDtd5Uk4cdhD0559292 intact-crc:6CE761F5D1CD05F1|rigid:d3rbAX8zcSe5biKUsfTOQVbeHj8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36107 uniprotkb:P09620 intact:EBI-2046036|uniprotkb:D6VXT3|uniprotkb:Q92324|ensemblfungi:YKL004W intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:aur1_yeast(display_long)|uniprotkb:YKL004W(locus name)|uniprotkb:AUR1(gene name)|psi-mi:AUR1(display_short)|uniprotkb:"Phosphatidylinositol:ceramide phosphoinositol transferase"(gene name synonym)|uniprotkb:Aureobasidin A resistance protein(gene name synonym) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326343|imex:IM-14275-1130 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012922.1|sgd:S000001487|dip:DIP-7196N|mint:P36107|ensemblfungi:YKL004W(gene)|ensemblfungi:YKL004W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0045140"(inositol phosphoceramide synthase activity)|go:"GO:0070916"(inositol phosphoceramide synthase complex)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR026841|interpro:IPR036938 ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:xAYM/Tmh0vH9boXai27Tlko4u/k559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:8D8AF99D0D81080B|rigid:C7Z1Uiez00lP3IAAo7JDXA5u2Ao false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39010 uniprotkb:P36107 intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C intact:EBI-2046036|uniprotkb:D6VXT3|uniprotkb:Q92324|ensemblfungi:YKL004W psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:aur1_yeast(display_long)|uniprotkb:YKL004W(locus name)|uniprotkb:AUR1(gene name)|psi-mi:AUR1(display_short)|uniprotkb:"Phosphatidylinositol:ceramide phosphoinositol transferase"(gene name synonym)|uniprotkb:Aureobasidin A resistance protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326354|imex:IM-14275-1131 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 refseq:NP_012922.1|sgd:S000001487|dip:DIP-7196N|mint:P36107|ensemblfungi:YKL004W(gene)|ensemblfungi:YKL004W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0045140"(inositol phosphoceramide synthase activity)|go:"GO:0070916"(inositol phosphoceramide synthase complex)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR026841|interpro:IPR036938 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 rogid:xAYM/Tmh0vH9boXai27Tlko4u/k559292 intact-crc:D02B3957B8438711|rigid:9n+7pU+INU1Z1+3imo5FHbj2jeM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41810 uniprotkb:P36107 intact:EBI-4869|uniprotkb:Q03779|uniprotkb:D6VSL9|ensemblfungi:YDR238C intact:EBI-2046036|uniprotkb:D6VXT3|uniprotkb:Q92324|ensemblfungi:YKL004W psi-mi:copb_yeast(display_long)|uniprotkb:SEC26(gene name)|psi-mi:SEC26(display_short)|uniprotkb:YDR238C(locus name)|uniprotkb:YD8419.05C(orf name)|uniprotkb:Beta-coat protein(gene name synonym) psi-mi:aur1_yeast(display_long)|uniprotkb:YKL004W(locus name)|uniprotkb:AUR1(gene name)|psi-mi:AUR1(display_short)|uniprotkb:"Phosphatidylinositol:ceramide phosphoinositol transferase"(gene name synonym)|uniprotkb:Aureobasidin A resistance protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326365|imex:IM-14275-1132 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002646|refseq:NP_010524.3|dip:DIP-6467N|mint:P41810|ensemblfungi:YDR238C(gene)|ensemblfungi:YDR238C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|reactome:R-SCE-6798695|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_012922.1|sgd:S000001487|dip:DIP-7196N|mint:P36107|ensemblfungi:YKL004W(gene)|ensemblfungi:YKL004W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0045140"(inositol phosphoceramide synthase activity)|go:"GO:0070916"(inositol phosphoceramide synthase complex)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR026841|interpro:IPR036938 psi-mi:"MI:0469"(intact) crc64:885420DB026BCFA3 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZfLp1BUmvVuTiXn7/Zbf/3m6VtE559292 rogid:xAYM/Tmh0vH9boXai27Tlko4u/k559292 intact-crc:32D57004B704A86E|rigid:ACo+v3d7AVYvZVmtKqbMTR7cpuo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41811 uniprotkb:P36107 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W intact:EBI-2046036|uniprotkb:D6VXT3|uniprotkb:Q92324|ensemblfungi:YKL004W psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:aur1_yeast(display_long)|uniprotkb:YKL004W(locus name)|uniprotkb:AUR1(gene name)|psi-mi:AUR1(display_short)|uniprotkb:"Phosphatidylinositol:ceramide phosphoinositol transferase"(gene name synonym)|uniprotkb:Aureobasidin A resistance protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326376|imex:IM-14275-1133 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_012922.1|sgd:S000001487|dip:DIP-7196N|mint:P36107|ensemblfungi:YKL004W(gene)|ensemblfungi:YKL004W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0045140"(inositol phosphoceramide synthase activity)|go:"GO:0070916"(inositol phosphoceramide synthase complex)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR026841|interpro:IPR036938 psi-mi:"MI:0469"(intact) crc64:6A5E50BBEB02CB58 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 rogid:xAYM/Tmh0vH9boXai27Tlko4u/k559292 intact-crc:AD6C7B2292F0F63A|rigid:fYyCNcXNM+iCUZJX0/5qCOfVdMM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36107 uniprotkb:P43621 intact:EBI-2046036|uniprotkb:D6VXT3|uniprotkb:Q92324|ensemblfungi:YKL004W intact:EBI-4876|uniprotkb:D6VTT4|ensemblfungi:YFR051C psi-mi:aur1_yeast(display_long)|uniprotkb:YKL004W(locus name)|uniprotkb:AUR1(gene name)|psi-mi:AUR1(display_short)|uniprotkb:"Phosphatidylinositol:ceramide phosphoinositol transferase"(gene name synonym)|uniprotkb:Aureobasidin A resistance protein(gene name synonym) psi-mi:copd_yeast(display_long)|uniprotkb:RET2(gene name)|psi-mi:RET2(display_short)|uniprotkb:YFR051C(locus name)|uniprotkb:Delta-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326387|imex:IM-14275-1134 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012922.1|sgd:S000001487|dip:DIP-7196N|mint:P36107|ensemblfungi:YKL004W(gene)|ensemblfungi:YKL004W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0045140"(inositol phosphoceramide synthase activity)|go:"GO:0070916"(inositol phosphoceramide synthase complex)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR026841|interpro:IPR036938 sgd:S000001947|refseq:NP_116709.3|dip:DIP-5255N|mint:P43621|ensemblfungi:YFR051C(gene)|ensemblfungi:YFR051C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|rcsb pdb:5FJW|rcsb pdb:5FJX|rcsb pdb:5FJZ|rcsb pdb:5FK0|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - crc64:AA730F046655EE5A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:xAYM/Tmh0vH9boXai27Tlko4u/k559292 rogid:auvjuT8ffm1R4P3mRKEIWAsynW0559292 intact-crc:989F2EDEE96D5508|rigid:sEzrmuygtPPulokNu4mysnqwFCw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53728 uniprotkb:P36107 intact:EBI-5444|uniprotkb:E9P900|uniprotkb:D6W1K2|ensemblfungi:YNR028W intact:EBI-2046036|uniprotkb:D6VXT3|uniprotkb:Q92324|ensemblfungi:YKL004W psi-mi:cyp8_yeast(display_long)|uniprotkb:CPR8(gene name)|psi-mi:CPR8(display_short)|uniprotkb:YNR028W(locus name)|uniprotkb:N3255(orf name)|uniprotkb:Rotamase CYP8(gene name synonym) psi-mi:aur1_yeast(display_long)|uniprotkb:YKL004W(locus name)|uniprotkb:AUR1(gene name)|psi-mi:AUR1(display_short)|uniprotkb:"Phosphatidylinositol:ceramide phosphoinositol transferase"(gene name synonym)|uniprotkb:Aureobasidin A resistance protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326398|imex:IM-14275-1135 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005311|refseq:NP_014425.3|dip:DIP-4261N|mint:P53728|ensemblfungi:YNR028W(gene)|ensemblfungi:YNR028W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR029000 refseq:NP_012922.1|sgd:S000001487|dip:DIP-7196N|mint:P36107|ensemblfungi:YKL004W(gene)|ensemblfungi:YKL004W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0045140"(inositol phosphoceramide synthase activity)|go:"GO:0070916"(inositol phosphoceramide synthase complex)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR026841|interpro:IPR036938 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:PWJO9W+2WFHhC6Fl3xoH0rw9a2w559292 rogid:xAYM/Tmh0vH9boXai27Tlko4u/k559292 intact-crc:A457EEF1B7A4D729|rigid:jH3aI/RWHG3or5+8eUcipU8S79U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54858 uniprotkb:P36107 intact:EBI-6042|uniprotkb:D6VS54|ensemblfungi:YDR068W intact:EBI-2046036|uniprotkb:D6VXT3|uniprotkb:Q92324|ensemblfungi:YKL004W psi-mi:dos2_yeast(display_long)|uniprotkb:D4267(orf name)|uniprotkb:YD8554.01(orf name)|uniprotkb:YD9609.22(orf name)|uniprotkb:DOS2(gene name)|psi-mi:DOS2(display_short)|uniprotkb:YDR068W(locus name) psi-mi:aur1_yeast(display_long)|uniprotkb:YKL004W(locus name)|uniprotkb:AUR1(gene name)|psi-mi:AUR1(display_short)|uniprotkb:"Phosphatidylinositol:ceramide phosphoinositol transferase"(gene name synonym)|uniprotkb:Aureobasidin A resistance protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326409|imex:IM-14275-1136 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002475|refseq:NP_010353.3|dip:DIP-4785N|mint:P54858|ensemblfungi:YDR068W(gene)|ensemblfungi:YDR068W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR005607(BSD)|interpro:IPR035925 refseq:NP_012922.1|sgd:S000001487|dip:DIP-7196N|mint:P36107|ensemblfungi:YKL004W(gene)|ensemblfungi:YKL004W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0045140"(inositol phosphoceramide synthase activity)|go:"GO:0070916"(inositol phosphoceramide synthase complex)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR026841|interpro:IPR036938 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:/4fnAAPmC12DMUbUB8MVS9yjjeg559292 rogid:xAYM/Tmh0vH9boXai27Tlko4u/k559292 intact-crc:AACE666902AF3E24|rigid:dJKn/Gnt/HNBS03083+A3SlDt14 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03687 uniprotkb:P36107 intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W intact:EBI-2046036|uniprotkb:D6VXT3|uniprotkb:Q92324|ensemblfungi:YKL004W psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:aur1_yeast(display_long)|uniprotkb:YKL004W(locus name)|uniprotkb:AUR1(gene name)|psi-mi:AUR1(display_short)|uniprotkb:"Phosphatidylinositol:ceramide phosphoinositol transferase"(gene name synonym)|uniprotkb:Aureobasidin A resistance protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326420|imex:IM-14275-1137 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) refseq:NP_012922.1|sgd:S000001487|dip:DIP-7196N|mint:P36107|ensemblfungi:YKL004W(gene)|ensemblfungi:YKL004W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0045140"(inositol phosphoceramide synthase activity)|go:"GO:0070916"(inositol phosphoceramide synthase complex)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR026841|interpro:IPR036938 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 rogid:xAYM/Tmh0vH9boXai27Tlko4u/k559292 intact-crc:4564BCBF678B4F2F|rigid:72y+AmBXJZtedbN34fMKwCO4t4g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36107 uniprotkb:Q12270 intact:EBI-2046036|uniprotkb:D6VXT3|uniprotkb:Q92324|ensemblfungi:YKL004W intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:aur1_yeast(display_long)|uniprotkb:YKL004W(locus name)|uniprotkb:AUR1(gene name)|psi-mi:AUR1(display_short)|uniprotkb:"Phosphatidylinositol:ceramide phosphoinositol transferase"(gene name synonym)|uniprotkb:Aureobasidin A resistance protein(gene name synonym) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326431|imex:IM-14275-1138 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012922.1|sgd:S000001487|dip:DIP-7196N|mint:P36107|ensemblfungi:YKL004W(gene)|ensemblfungi:YKL004W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0045140"(inositol phosphoceramide synthase activity)|go:"GO:0070916"(inositol phosphoceramide synthase complex)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR026841|interpro:IPR036938 refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:xAYM/Tmh0vH9boXai27Tlko4u/k559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:143DFACF97BA013A|rigid:/JXiPHUohahmLmWjEUW9HVidKdk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36108 uniprotkb:P36108 intact:EBI-26574|uniprotkb:D6VXT5|ensemblfungi:YKL002W intact:EBI-26574|uniprotkb:D6VXT5|ensemblfungi:YKL002W psi-mi:did4_yeast(display_long)|uniprotkb:VPL2(gene name synonym)|uniprotkb:VPS2(gene name synonym)|uniprotkb:VPT14(gene name synonym)|uniprotkb:YKL002W(locus name)|uniprotkb:DID4(gene name)|psi-mi:DID4(display_short)|uniprotkb:CHM2(gene name synonym)|uniprotkb:GRD7(gene name synonym)|uniprotkb:REN1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 2(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 14(gene name synonym)|uniprotkb:ESCRT-III complex subunit VPS2(gene name synonym) psi-mi:did4_yeast(display_long)|uniprotkb:VPL2(gene name synonym)|uniprotkb:VPS2(gene name synonym)|uniprotkb:VPT14(gene name synonym)|uniprotkb:YKL002W(locus name)|uniprotkb:DID4(gene name)|psi-mi:DID4(display_short)|uniprotkb:CHM2(gene name synonym)|uniprotkb:GRD7(gene name synonym)|uniprotkb:REN1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 2(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 14(gene name synonym)|uniprotkb:ESCRT-III complex subunit VPS2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326442|imex:IM-14275-1139 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012924.2|sgd:S000001485|mint:P36108|dip:DIP-1916N|ensemblfungi:YKL002W(gene)|ensemblfungi:YKL002W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR005024(Snf7)|rcsb pdb:2V6X|rcsb pdb:6AP1|rcsb pdb:6BMF|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328 refseq:NP_012924.2|sgd:S000001485|mint:P36108|dip:DIP-1916N|ensemblfungi:YKL002W(gene)|ensemblfungi:YKL002W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR005024(Snf7)|rcsb pdb:2V6X|rcsb pdb:6AP1|rcsb pdb:6BMF|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328 psi-mi:"MI:0469"(intact) crc64:200D07DB4C45DCBC crc64:200D07DB4C45DCBC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iQ8lcGhal3Pt46dwcOkIW2fp/G0559292 rogid:iQ8lcGhal3Pt46dwcOkIW2fp/G0559292 intact-crc:6F2BB85D842A6C14|rigid:dceF9vZ16FanW0Pi/1Hff3iUqz4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39929 uniprotkb:P36108 intact:EBI-17554|uniprotkb:D6VY27|ensemblfungi:YLR025W|uniprotkb:E9P8V6 intact:EBI-26574|uniprotkb:D6VXT5|ensemblfungi:YKL002W psi-mi:snf7_yeast(display_long)|uniprotkb:SNF7(gene name)|psi-mi:SNF7(display_short)|uniprotkb:VPS32(gene name synonym)|uniprotkb:YLR025W(locus name)|uniprotkb:DID1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 32(gene name synonym)|uniprotkb:DOA4-independent degradation protein 1(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 7(gene name synonym) psi-mi:did4_yeast(display_long)|uniprotkb:VPL2(gene name synonym)|uniprotkb:VPS2(gene name synonym)|uniprotkb:VPT14(gene name synonym)|uniprotkb:YKL002W(locus name)|uniprotkb:DID4(gene name)|psi-mi:DID4(display_short)|uniprotkb:CHM2(gene name synonym)|uniprotkb:GRD7(gene name synonym)|uniprotkb:REN1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 2(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 14(gene name synonym)|uniprotkb:ESCRT-III complex subunit VPS2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326453|imex:IM-14275-1140 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013125.1|sgd:S000004015|ensemblfungi:YLR025W(gene)|ensemblfungi:YLR025W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0071454"(cellular response to anoxia)|go:"GO:1904669"(ATP export)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|rcsb pdb:5FD7|rcsb pdb:5FD9|rcsb pdb:5T8L|rcsb pdb:5T8N|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1747N|mint:P39929 refseq:NP_012924.2|sgd:S000001485|mint:P36108|dip:DIP-1916N|ensemblfungi:YKL002W(gene)|ensemblfungi:YKL002W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR005024(Snf7)|rcsb pdb:2V6X|rcsb pdb:6AP1|rcsb pdb:6BMF|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328 psi-mi:"MI:0469"(intact) crc64:5241A18BB181F0C1 crc64:200D07DB4C45DCBC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I8qBtNlqTjxLX1HginTOzM3o9oA559292 rogid:iQ8lcGhal3Pt46dwcOkIW2fp/G0559292 intact-crc:DB6100C653CC3688|rigid:ARVmLKQtRd3YUBo6cMlUxg8D4I4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P69771 uniprotkb:P36108 intact:EBI-2053489|uniprotkb:D6VX98|ensemblfungi:YKR035W-A intact:EBI-26574|uniprotkb:D6VXT5|ensemblfungi:YKL002W psi-mi:did2_yeast(display_long)|uniprotkb:CHM1(gene name synonym)|uniprotkb:FTI1(gene name synonym)|uniprotkb:Fifty two inhibitor 1(gene name synonym)|uniprotkb:YKR035W-A(locus name)|uniprotkb:VPS46(gene name synonym)|uniprotkb:Charged multivesicular body protein 1(gene name synonym)|uniprotkb:DOA4-independent degradation protein 2(gene name synonym)|uniprotkb:DID2(gene name)|psi-mi:DID2(display_short) psi-mi:did4_yeast(display_long)|uniprotkb:VPL2(gene name synonym)|uniprotkb:VPS2(gene name synonym)|uniprotkb:VPT14(gene name synonym)|uniprotkb:YKL002W(locus name)|uniprotkb:DID4(gene name)|psi-mi:DID4(display_short)|uniprotkb:CHM2(gene name synonym)|uniprotkb:GRD7(gene name synonym)|uniprotkb:REN1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 2(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 14(gene name synonym)|uniprotkb:ESCRT-III complex subunit VPS2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326464|imex:IM-14275-1141 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006435|refseq:NP_012961.3|dip:DIP-52223N|mint:P69771|ensemblfungi:YKR035W-A(gene)|ensemblfungi:YKR035W-A_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|rcsb pdb:3GGZ|rcsb pdb:5H7P refseq:NP_012924.2|sgd:S000001485|mint:P36108|dip:DIP-1916N|ensemblfungi:YKL002W(gene)|ensemblfungi:YKL002W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR005024(Snf7)|rcsb pdb:2V6X|rcsb pdb:6AP1|rcsb pdb:6BMF|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328 psi-mi:"MI:0469"(intact) crc64:70D1CF4588A8C6E6 crc64:200D07DB4C45DCBC figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SVI1+8lRI6qwD0CSLY11Xq0LG0o559292 rogid:iQ8lcGhal3Pt46dwcOkIW2fp/G0559292 intact-crc:EDB849FA8064352D|rigid:gOyejmkt9NlF7X4xQsUmp6MhSqg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36132 uniprotkb:P53323 intact:EBI-26411|uniprotkb:D6VXA1|ensemblfungi:YKR038C intact:EBI-3809|uniprotkb:D6VV41|ensemblfungi:YGR262C psi-mi:kae1_yeast(display_long)|uniprotkb:KAE1(gene name)|psi-mi:KAE1(display_short)|uniprotkb:"t(6)A37 threonylcarbamoyladenosine biosynthesis protein KAE1"(gene name synonym)|uniprotkb:Kinase-associated endopeptidase 1(gene name synonym)|uniprotkb:tRNA threonylcarbamoyladenosine biosynthesis protein KAE1(gene name synonym)|uniprotkb:YKR038C(locus name)|uniprotkb:N6-L-threonylcarbamoyladenine synthase(gene name synonym) psi-mi:bud32_yeast(display_long)|uniprotkb:YGR262C(locus name)|uniprotkb:BUD32(gene name)|psi-mi:BUD32(display_short)|uniprotkb:LDB14(gene name synonym)|uniprotkb:piD261(gene name synonym)|uniprotkb:Low-dye-binding protein 14(gene name synonym)|uniprotkb:Atypical serine/threonine protein kinase BUD32(gene name synonym)|uniprotkb:Bud site selection protein 32(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326475|imex:IM-14275-1142 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012964.2|sgd:S000001746|mint:P36132|dip:DIP-6421N|ensemblfungi:YKR038C(gene)|ensemblfungi:YKR038C_mRNA(transcript)|go:"GO:0000408"(EKC/KEOPS complex)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051276"(chromosome organization)|go:"GO:0061711"("N(6)-L-threonylcarbamoyladenine synthase activity")|go:"GO:0070525"(tRNA threonylcarbamoyladenosine metabolic process)|interpro:IPR000905(Peptidase M22, glycoprotease)|interpro:IPR017860|interpro:IPR017861|interpro:IPR034680|interpro:IPR043129 refseq:NP_011778.1|sgd:S000003494|dip:DIP-5008N|mint:P53323|ensemblfungi:YGR262C(gene)|ensemblfungi:YGR262C_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000408"(EKC/KEOPS complex)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070525"(tRNA threonylcarbamoyladenosine metabolic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR022495|rcsb pdb:4WW5|rcsb pdb:4WW7|rcsb pdb:4WW9|rcsb pdb:4WWA psi-mi:"MI:0469"(intact) crc64:76A73F2E9E26CF4C crc64:D12E97BAE21B3385 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vmjWZq81rCxXMBZGS730dy0i0xI559292 rogid:Z/IOFJ/BNmjMhZvK7L123btIlck559292 intact-crc:A0B5A6889FDA2340|rigid:zUKbUTIQTjx5HnVFd5JZPvuwjqk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36148 uniprotkb:P35196 intact:EBI-26471|uniprotkb:D6VXC8|ensemblfungi:YKR067W intact:EBI-14943|uniprotkb:D6VQ03|ensemblfungi:YBR002C psi-mi:gpt2_yeast(display_long)|uniprotkb:YKR067W(locus name)|uniprotkb:GPT2(gene name)|psi-mi:GPT2(display_short)|uniprotkb:GAT1(gene name synonym)|uniprotkb:Dihydroxyacetone phosphate acyltransferase 2(gene name synonym)|uniprotkb:Glycerol-3-phosphate / dihydroxyacetone phosphate acyltransferase 2(gene name synonym) psi-mi:rer2_yeast(display_long)|uniprotkb:"Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific)"(gene name synonym)|uniprotkb:YBR0107(orf name)|uniprotkb:RER2(gene name)|psi-mi:RER2(display_short)|uniprotkb:YBR002C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326486|imex:IM-14275-1143 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001775|refseq:NP_012993.3|mint:P36148|dip:DIP-6620N|ensemblfungi:YKR067W(gene)|ensemblfungi:YKR067W_mRNA(transcript)|go:"GO:0004366"(glycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0016287"(glycerone-phosphate O-acyltransferase activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0090207"(regulation of triglyceride metabolic process)|go:"GO:0102420"("sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity")|interpro:IPR002123(Phospholipid/glycerol acyltransferase) interpro:IPR036424|refseq:NP_009556.1|sgd:S000000206|interpro:IPR001441(Di-trans-poly-cis-decaprenylcistransferase)|interpro:IPR018520|ensemblfungi:YBR002C(gene)|ensemblfungi:YBR002C_mRNA(transcript)|go:"GO:0002094"(polyprenyltransferase activity)|go:"GO:0004659"(prenyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016094"(polyprenol biosynthetic process)|go:"GO:0019408"(dolichol biosynthetic process)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0045547"(dehydrodolichyl diphosphate synthase activity)|go:"GO:1904423"(dehydrodolichyl diphosphate synthase complex)|reactome:R-SCE-446199|mint:P35196 psi-mi:"MI:0469"(intact) crc64:84B9946E56B82F15 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vHwE5y3AXWOm1SxNz0K3oLTUATI559292 rogid:gVl9E/6GKqKsUp/5VLdT5XGbjUM559292 intact-crc:37FE97D4475FA2E2|rigid:r5/AwVmsueblfRcLTAKbuJl1M08 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36148 uniprotkb:P40350 intact:EBI-26471|uniprotkb:D6VXC8|ensemblfungi:YKR067W intact:EBI-2470|uniprotkb:D6W3E3|ensemblfungi:YPL227C psi-mi:gpt2_yeast(display_long)|uniprotkb:YKR067W(locus name)|uniprotkb:GPT2(gene name)|psi-mi:GPT2(display_short)|uniprotkb:GAT1(gene name synonym)|uniprotkb:Dihydroxyacetone phosphate acyltransferase 2(gene name synonym)|uniprotkb:Glycerol-3-phosphate / dihydroxyacetone phosphate acyltransferase 2(gene name synonym) psi-mi:alg5_yeast(display_long)|uniprotkb:ALG5(gene name)|psi-mi:ALG5(display_short)|uniprotkb:YPL227C(locus name)|uniprotkb:P1437(orf name)|uniprotkb:Asparagine-linked glycosylation protein 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326497|imex:IM-14275-1144 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001775|refseq:NP_012993.3|mint:P36148|dip:DIP-6620N|ensemblfungi:YKR067W(gene)|ensemblfungi:YKR067W_mRNA(transcript)|go:"GO:0004366"(glycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0016287"(glycerone-phosphate O-acyltransferase activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0090207"(regulation of triglyceride metabolic process)|go:"GO:0102420"("sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity")|interpro:IPR002123(Phospholipid/glycerol acyltransferase) refseq:NP_015097.1|sgd:S000006148|dip:DIP-5651N|mint:P40350|ensemblfungi:YPL227C(gene)|ensemblfungi:YPL227C_mRNA(transcript)|go:"GO:0004581"(dolichyl-phosphate beta-glucosyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR035518|reactome:R-SCE-480985 psi-mi:"MI:0469"(intact) crc64:84B9946E56B82F15 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vHwE5y3AXWOm1SxNz0K3oLTUATI559292 rogid:aKi97cbwqo7kNWhtRyzG3UOLH4U559292 intact-crc:C1E9D84E1996F333|rigid:Lg/rPWSvni7eHNMsrD1k5zJHVnM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03835 uniprotkb:P36152 intact:EBI-22178|uniprotkb:D6VS83|ensemblfungi:YDR098C intact:EBI-26482|uniprotkb:D6VXD2|ensemblfungi:YKR071C psi-mi:glrx3_yeast(display_long)|uniprotkb:YD8557.05C(orf name)|uniprotkb:GRX3(gene name)|psi-mi:GRX3(display_short)|uniprotkb:YDR098C(locus name) psi-mi:dre2_yeast(display_long)|uniprotkb:YKR071C(locus name)|uniprotkb:DRE2(gene name)|psi-mi:DRE2(display_short)|uniprotkb:Anamorsin homolog(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326508|imex:IM-14275-1145 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002505|refseq:NP_010383.4|dip:DIP-1350N|mint:Q03835|ensemblfungi:YDR098C(gene)|ensemblfungi:YDR098C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097573"(glutathione oxidoreductase activity)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR033658|interpro:IPR036249|rcsb pdb:3D6I|rcsb pdb:5Y4U sgd:S000001779|refseq:NP_012997.3|mint:P36152|dip:DIP-6716N|ensemblfungi:YKR071C(gene)|ensemblfungi:YKR071C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|interpro:IPR007785(Protein of unknown function DUF689)|interpro:IPR031838|rcsb pdb:2KM1 psi-mi:"MI:0469"(intact) crc64:8CC1A04EC1E7DAB3 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2015/11/09 rogid:Vjth+XO73fWvOUEPxBfvqKS+V0c559292 rogid:0QsPVhkahwln/ULEm8uB6eq4/vc559292 intact-crc:FD8395FF4A10D8BE|rigid:8qQQJGsWkoER1uNRFBI49yHPfaM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36165 uniprotkb:Q12168 intact:EBI-26531|uniprotkb:D6VXE9|ensemblfungi:YKR089C intact:EBI-32973|uniprotkb:Q07268|uniprotkb:D6VYD8|ensemblfungi:YLR144C psi-mi:tgl4_yeast(display_long)|uniprotkb:YKR089C(locus name)|uniprotkb:YKR409(orf name)|uniprotkb:TGL4(gene name)|psi-mi:TGL4(display_short)|uniprotkb:STC1(gene name synonym)|uniprotkb:Lipase 4(gene name synonym) psi-mi:eng2_yeast(display_long)|uniprotkb:ACF2(gene name)|psi-mi:ACF2(display_short)|uniprotkb:YLR144C(locus name)|uniprotkb:Laminarinase-2(gene name synonym)|uniprotkb:ENG2(gene name synonym)|uniprotkb:PCA1(gene name synonym)|uniprotkb:L3180(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326519|imex:IM-14275-1146 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013015.1|sgd:S000001797|mint:P36165|dip:DIP-5588N|ensemblfungi:YKR089C(gene)|ensemblfungi:YKR089C_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007114"(cell budding)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042171"(lysophosphatidic acid acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|interpro:IPR002641(Patatin)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR021771 refseq:NP_013245.1|sgd:S000004134|mint:Q12168|dip:DIP-2889N|ensemblfungi:YLR144C(gene)|ensemblfungi:YLR144C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042973"(glucan endo-1,3-beta-D-glucosidase activity)|go:"GO:0052861"(glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group)|go:"GO:0052862"(glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group)|interpro:IPR005200(Glycoside hydrolase, family 81)|interpro:IPR040451|interpro:IPR040720 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VEfeOj6QZCY2MIMeme5kaVZBQx8559292 rogid:8STCUe6Ie2CnTTBMjY8wrld5h44559292 intact-crc:D81FFA37E22B4C0A|rigid:4OznRlY3Cp83Zgq0YKQWcSkyB/I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24276 uniprotkb:P37012 intact:EBI-18153|uniprotkb:D6VSS2|ensemblfungi:YDR293C intact:EBI-13296|uniprotkb:D6VZS7|ensemblfungi:YMR105C psi-mi:ssd1_yeast(display_long)|uniprotkb:SSD1(gene name)|psi-mi:SSD1(display_short)|uniprotkb:CLA1(gene name synonym)|uniprotkb:RLD1(gene name synonym)|uniprotkb:SRK1(gene name synonym)|uniprotkb:YDR293C(locus name)|uniprotkb:D9819.4(orf name)|uniprotkb:Protein SRK1(gene name synonym) psi-mi:pgm2_yeast(display_long)|uniprotkb:PGM2(gene name)|psi-mi:PGM2(display_short)|uniprotkb:GAL5(gene name synonym)|uniprotkb:YMR105C(locus name)|uniprotkb:YM9718.04C(orf name)|uniprotkb:Glucose phosphomutase 2(gene name synonym)|uniprotkb:"D-glucose-1,6-diphosphate:D-glucose-1-phosphate phosphotransferase"(gene name synonym)|uniprotkb:GA-5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326530|imex:IM-14275-1147 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010579.1|sgd:S000002701|ensemblfungi:YDR293C(gene)|ensemblfungi:YDR293C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051301"(cell division)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR041093|interpro:IPR041505|rcsb pdb:5NCL|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007049"(cell cycle)|dip:DIP-6449N|mint:P24276 refseq:NP_013823.1|sgd:S000004711|mint:P37012|dip:DIP-6499N|ensemblfungi:YMR105C(gene)|ensemblfungi:YMR105C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004614"(phosphoglucomutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019255"(glucose 1-phosphate metabolic process)|go:"GO:0019388"(galactose catabolic process)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR036900 psi-mi:"MI:0469"(intact) crc64:3D50FD6838ECA514 crc64:45B78AFF8197645E figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:myt8+lnu2/li6TuGiM5GBfMtUiw559292 rogid:miT4vpKTbsa/OfXIppW6h1+TbPs559292 intact-crc:28BABA8670E3D0BA|rigid:0KDRDYA1PNcz4w6MyYNrWeqgLXQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37012 uniprotkb:P32610 intact:EBI-13296|uniprotkb:D6VZS7|ensemblfungi:YMR105C intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W psi-mi:pgm2_yeast(display_long)|uniprotkb:PGM2(gene name)|psi-mi:PGM2(display_short)|uniprotkb:GAL5(gene name synonym)|uniprotkb:YMR105C(locus name)|uniprotkb:YM9718.04C(orf name)|uniprotkb:Glucose phosphomutase 2(gene name synonym)|uniprotkb:"D-glucose-1,6-diphosphate:D-glucose-1-phosphate phosphotransferase"(gene name synonym)|uniprotkb:GA-5(gene name synonym) psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326541|imex:IM-14275-1148 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013823.1|sgd:S000004711|mint:P37012|dip:DIP-6499N|ensemblfungi:YMR105C(gene)|ensemblfungi:YMR105C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004614"(phosphoglucomutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019255"(glucose 1-phosphate metabolic process)|go:"GO:0019388"(galactose catabolic process)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR036900 refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610 psi-mi:"MI:0469"(intact) crc64:45B78AFF8197645E crc64:FDE93E1FAF0AEC5B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miT4vpKTbsa/OfXIppW6h1+TbPs559292 rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292 intact-crc:45F72054856B7A0A|rigid:axPMK/FP0WGYN+iJGuDyWjq6cKg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37012 uniprotkb:P37012 intact:EBI-13296|uniprotkb:D6VZS7|ensemblfungi:YMR105C intact:EBI-13296|uniprotkb:D6VZS7|ensemblfungi:YMR105C psi-mi:pgm2_yeast(display_long)|uniprotkb:PGM2(gene name)|psi-mi:PGM2(display_short)|uniprotkb:GAL5(gene name synonym)|uniprotkb:YMR105C(locus name)|uniprotkb:YM9718.04C(orf name)|uniprotkb:Glucose phosphomutase 2(gene name synonym)|uniprotkb:"D-glucose-1,6-diphosphate:D-glucose-1-phosphate phosphotransferase"(gene name synonym)|uniprotkb:GA-5(gene name synonym) psi-mi:pgm2_yeast(display_long)|uniprotkb:PGM2(gene name)|psi-mi:PGM2(display_short)|uniprotkb:GAL5(gene name synonym)|uniprotkb:YMR105C(locus name)|uniprotkb:YM9718.04C(orf name)|uniprotkb:Glucose phosphomutase 2(gene name synonym)|uniprotkb:"D-glucose-1,6-diphosphate:D-glucose-1-phosphate phosphotransferase"(gene name synonym)|uniprotkb:GA-5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326552|imex:IM-14275-1149 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013823.1|sgd:S000004711|mint:P37012|dip:DIP-6499N|ensemblfungi:YMR105C(gene)|ensemblfungi:YMR105C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004614"(phosphoglucomutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019255"(glucose 1-phosphate metabolic process)|go:"GO:0019388"(galactose catabolic process)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR036900 refseq:NP_013823.1|sgd:S000004711|mint:P37012|dip:DIP-6499N|ensemblfungi:YMR105C(gene)|ensemblfungi:YMR105C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004614"(phosphoglucomutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019255"(glucose 1-phosphate metabolic process)|go:"GO:0019388"(galactose catabolic process)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR036900 psi-mi:"MI:0469"(intact) crc64:45B78AFF8197645E crc64:45B78AFF8197645E figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miT4vpKTbsa/OfXIppW6h1+TbPs559292 rogid:miT4vpKTbsa/OfXIppW6h1+TbPs559292 intact-crc:7A50CE80E1EEE75D|rigid:9koMNbE9pfGZzdn0/K3Axrhx2+U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38009 uniprotkb:P37012 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 intact:EBI-13296|uniprotkb:D6VZS7|ensemblfungi:YMR105C psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:pgm2_yeast(display_long)|uniprotkb:PGM2(gene name)|psi-mi:PGM2(display_short)|uniprotkb:GAL5(gene name synonym)|uniprotkb:YMR105C(locus name)|uniprotkb:YM9718.04C(orf name)|uniprotkb:Glucose phosphomutase 2(gene name synonym)|uniprotkb:"D-glucose-1,6-diphosphate:D-glucose-1-phosphate phosphotransferase"(gene name synonym)|uniprotkb:GA-5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326563|imex:IM-14275-1150 author score:99.32 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N refseq:NP_013823.1|sgd:S000004711|mint:P37012|dip:DIP-6499N|ensemblfungi:YMR105C(gene)|ensemblfungi:YMR105C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004614"(phosphoglucomutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019255"(glucose 1-phosphate metabolic process)|go:"GO:0019388"(galactose catabolic process)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR036900 psi-mi:"MI:0469"(intact) crc64:8ABA71761B512242 crc64:45B78AFF8197645E figure legend:tables S3 and S4|author-confidence:99.32|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 rogid:miT4vpKTbsa/OfXIppW6h1+TbPs559292 intact-crc:A5C96D63611DC08F|rigid:/o2ZffkFgOyRqv/c9OOOghCxLps false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37012 uniprotkb:P38328 intact:EBI-13296|uniprotkb:D6VZS7|ensemblfungi:YMR105C intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C psi-mi:pgm2_yeast(display_long)|uniprotkb:PGM2(gene name)|psi-mi:PGM2(display_short)|uniprotkb:GAL5(gene name synonym)|uniprotkb:YMR105C(locus name)|uniprotkb:YM9718.04C(orf name)|uniprotkb:Glucose phosphomutase 2(gene name synonym)|uniprotkb:"D-glucose-1,6-diphosphate:D-glucose-1-phosphate phosphotransferase"(gene name synonym)|uniprotkb:GA-5(gene name synonym) psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326574|imex:IM-14275-1151 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013823.1|sgd:S000004711|mint:P37012|dip:DIP-6499N|ensemblfungi:YMR105C(gene)|ensemblfungi:YMR105C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004614"(phosphoglucomutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019255"(glucose 1-phosphate metabolic process)|go:"GO:0019388"(galactose catabolic process)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR036900 sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:45B78AFF8197645E crc64:D75C6BB8EC35EEDF figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miT4vpKTbsa/OfXIppW6h1+TbPs559292 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 intact-crc:593F93E81DE8187B|rigid:IXt/wjeM1Fjbhb1MaPHJKUt8ObI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37012 uniprotkb:P41811 intact:EBI-13296|uniprotkb:D6VZS7|ensemblfungi:YMR105C intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:pgm2_yeast(display_long)|uniprotkb:PGM2(gene name)|psi-mi:PGM2(display_short)|uniprotkb:GAL5(gene name synonym)|uniprotkb:YMR105C(locus name)|uniprotkb:YM9718.04C(orf name)|uniprotkb:Glucose phosphomutase 2(gene name synonym)|uniprotkb:"D-glucose-1,6-diphosphate:D-glucose-1-phosphate phosphotransferase"(gene name synonym)|uniprotkb:GA-5(gene name synonym) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326585|imex:IM-14275-1152 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013823.1|sgd:S000004711|mint:P37012|dip:DIP-6499N|ensemblfungi:YMR105C(gene)|ensemblfungi:YMR105C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004614"(phosphoglucomutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019255"(glucose 1-phosphate metabolic process)|go:"GO:0019388"(galactose catabolic process)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR036900 refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:45B78AFF8197645E crc64:6A5E50BBEB02CB58 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miT4vpKTbsa/OfXIppW6h1+TbPs559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:44117635DED6CF2C|rigid:JIWs9GbzTo5UXT+86Fbr9zg21OE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37012 uniprotkb:P53731 intact:EBI-13296|uniprotkb:D6VZS7|ensemblfungi:YMR105C intact:EBI-2770|uniprotkb:D6W1L1|ensemblfungi:YNR035C psi-mi:pgm2_yeast(display_long)|uniprotkb:PGM2(gene name)|psi-mi:PGM2(display_short)|uniprotkb:GAL5(gene name synonym)|uniprotkb:YMR105C(locus name)|uniprotkb:YM9718.04C(orf name)|uniprotkb:Glucose phosphomutase 2(gene name synonym)|uniprotkb:"D-glucose-1,6-diphosphate:D-glucose-1-phosphate phosphotransferase"(gene name synonym)|uniprotkb:GA-5(gene name synonym) psi-mi:arpc2_yeast(display_long)|uniprotkb:ARC35(gene name)|psi-mi:ARC35(display_short)|uniprotkb:YNR035C(locus name)|uniprotkb:N3296(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326596|imex:IM-14275-1153 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013823.1|sgd:S000004711|mint:P37012|dip:DIP-6499N|ensemblfungi:YMR105C(gene)|ensemblfungi:YMR105C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004614"(phosphoglucomutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019255"(glucose 1-phosphate metabolic process)|go:"GO:0019388"(galactose catabolic process)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR036900 refseq:NP_014433.1|sgd:S000005318|dip:DIP-2304N|mint:P53731|ensemblfungi:YNR035C(gene)|ensemblfungi:YNR035C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072697"(protein localization to cell cortex)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:45B78AFF8197645E crc64:9AF71A93688729F6 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miT4vpKTbsa/OfXIppW6h1+TbPs559292 rogid:URdgP2srz1O44fNGQh18L7bzC+c559292 intact-crc:4E037A2AD7F1B692|rigid:x0Sw3jztWrAyDIW3m7VnkJfQGKA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37012 uniprotkb:P54783 intact:EBI-13296|uniprotkb:D6VZS7|ensemblfungi:YMR105C intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:pgm2_yeast(display_long)|uniprotkb:PGM2(gene name)|psi-mi:PGM2(display_short)|uniprotkb:GAL5(gene name synonym)|uniprotkb:YMR105C(locus name)|uniprotkb:YM9718.04C(orf name)|uniprotkb:Glucose phosphomutase 2(gene name synonym)|uniprotkb:"D-glucose-1,6-diphosphate:D-glucose-1-phosphate phosphotransferase"(gene name synonym)|uniprotkb:GA-5(gene name synonym) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326607|imex:IM-14275-1154 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013823.1|sgd:S000004711|mint:P37012|dip:DIP-6499N|ensemblfungi:YMR105C(gene)|ensemblfungi:YMR105C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004614"(phosphoglucomutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019255"(glucose 1-phosphate metabolic process)|go:"GO:0019388"(galactose catabolic process)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR036900 go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) crc64:45B78AFF8197645E - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miT4vpKTbsa/OfXIppW6h1+TbPs559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:065D5ADCE86946D2|rigid:GaD1E5QvmHax9lBJykCcSsyZJnU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6Q5K6 uniprotkb:P37012 intact:EBI-392766|ensemblfungi:YML058W-A|uniprotkb:D6VZB5 intact:EBI-13296|uniprotkb:D6VZS7|ensemblfungi:YMR105C psi-mi:hug1_yeast(display_long)|uniprotkb:HUG1(gene name)|psi-mi:HUG1(display_short)|uniprotkb:YML058W-A(locus name) psi-mi:pgm2_yeast(display_long)|uniprotkb:PGM2(gene name)|psi-mi:PGM2(display_short)|uniprotkb:GAL5(gene name synonym)|uniprotkb:YMR105C(locus name)|uniprotkb:YM9718.04C(orf name)|uniprotkb:Glucose phosphomutase 2(gene name synonym)|uniprotkb:"D-glucose-1,6-diphosphate:D-glucose-1-phosphate phosphotransferase"(gene name synonym)|uniprotkb:GA-5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326618|imex:IM-14275-1155 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML058W-A(gene)|ensemblfungi:YML058W-A_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:1905117"(regulation of ribonucleoside-diphosphate reductase activity)|go:"GO:1990846"(ribonucleoside-diphosphate reductase inhibitor activity)|sgd:S000007472|refseq:NP_219498.1|mint:Q6Q5K6 refseq:NP_013823.1|sgd:S000004711|mint:P37012|dip:DIP-6499N|ensemblfungi:YMR105C(gene)|ensemblfungi:YMR105C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004614"(phosphoglucomutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019255"(glucose 1-phosphate metabolic process)|go:"GO:0019388"(galactose catabolic process)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR036900 psi-mi:"MI:0469"(intact) - crc64:45B78AFF8197645E figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:x+quBrnP+8yql7JGQ1NK4j5ubbw559292 rogid:miT4vpKTbsa/OfXIppW6h1+TbPs559292 intact-crc:5760B6F56336F701|rigid:1vFLeyXzxDHjQEL2qZiMOHux1N8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:P37020 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-7552|uniprotkb:D6VWL1|ensemblfungi:YJR040W psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:gef1_yeast(display_long)|uniprotkb:CLCY1(gene name synonym)|uniprotkb:GEF1(gene name)|psi-mi:GEF1(display_short)|uniprotkb:YJR040W(locus name)|uniprotkb:J1616(orf name)|uniprotkb:Voltage-gated chloride channel(gene name synonym)|uniprotkb:ClC-Y1(gene name synonym)|uniprotkb:ClC-A(gene name synonym)|uniprotkb:CLC protein GEF1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326629|imex:IM-14275-1156 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 refseq:NP_012574.1|sgd:S000003801|mint:P37020|dip:DIP-3949N|ensemblfungi:YJR040W(gene)|ensemblfungi:YJR040W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010008"(endosome membrane)|go:"GO:0015299"("solute:proton antiporter activity")|go:"GO:0034707"(chloride channel complex)|go:"GO:0034756"(regulation of iron ion transport)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR014743(Chloride channel, core)|reactome:R-SCE-2672351 psi-mi:"MI:0469"(intact) - crc64:544C751402D32E19 figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:zvAn6Y8qQ5nL+NTOGKKNGXOMof0559292 intact-crc:31F3C7FF0A2A78C8|rigid:qdGhQgRLrBQtSxtp52Bpl7h9oWs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37020 uniprotkb:P39010 intact:EBI-7552|uniprotkb:D6VWL1|ensemblfungi:YJR040W intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C psi-mi:gef1_yeast(display_long)|uniprotkb:CLCY1(gene name synonym)|uniprotkb:GEF1(gene name)|psi-mi:GEF1(display_short)|uniprotkb:YJR040W(locus name)|uniprotkb:J1616(orf name)|uniprotkb:Voltage-gated chloride channel(gene name synonym)|uniprotkb:ClC-Y1(gene name synonym)|uniprotkb:ClC-A(gene name synonym)|uniprotkb:CLC protein GEF1(gene name synonym) psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326640|imex:IM-14275-1157 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012574.1|sgd:S000003801|mint:P37020|dip:DIP-3949N|ensemblfungi:YJR040W(gene)|ensemblfungi:YJR040W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010008"(endosome membrane)|go:"GO:0015299"("solute:proton antiporter activity")|go:"GO:0034707"(chloride channel complex)|go:"GO:0034756"(regulation of iron ion transport)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR014743(Chloride channel, core)|reactome:R-SCE-2672351 refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 psi-mi:"MI:0469"(intact) crc64:544C751402D32E19 - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zvAn6Y8qQ5nL+NTOGKKNGXOMof0559292 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 intact-crc:8AF8B7298351042B|rigid:qhao6CPmBy1Y14CyWiK+KyRht8Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37261 uniprotkb:P32588 intact:EBI-21654|uniprotkb:Q8NIM8|uniprotkb:D6VQZ0|ensemblfungi:YCL026C-A intact:EBI-14231|ensemblfungi:YNL016W|uniprotkb:D6W1G2 psi-mi:frm2_yeast(display_long)|uniprotkb:FRM2(gene name)|psi-mi:FRM2(display_short)|uniprotkb:YCLX08C(orf name)|uniprotkb:YCLX8C(orf name)|uniprotkb:YCL026C-A(locus name) psi-mi:pub1_yeast(display_long)|uniprotkb:ARS consensus-binding protein ACBP-60(gene name synonym)|uniprotkb:Poly uridylate-binding protein(gene name synonym)|uniprotkb:PUB1(gene name)|psi-mi:PUB1(display_short)|uniprotkb:RNP1(gene name synonym)|uniprotkb:YNL016W(locus name)|uniprotkb:N2842(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326651|imex:IM-14275-1158 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009904.2|sgd:S000000589|mint:P37261|dip:DIP-3881N|ensemblfungi:YCL026C-A(gene)|ensemblfungi:YCL026C-A_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0016657"("oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045922"(negative regulation of fatty acid metabolic process)|interpro:IPR000415(Nitroreductase)|interpro:IPR033877|rcsb pdb:4URP|interpro:IPR029479 refseq:NP_014382.1|sgd:S000004961|ensemblfungi:YNL016W(gene)|ensemblfungi:YNL016W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043488"(regulation of mRNA stability)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034509|interpro:IPR034639|interpro:IPR035979|rcsb pdb:2LA4|rcsb pdb:3MD1|rcsb pdb:3MD3|rcsb pdb:6Z29|mint:P32588|dip:DIP-5480N psi-mi:"MI:0469"(intact) crc64:2F555CE7D9DBCE15 crc64:3B81A7735505D3CA figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GIKcRWDVOk+pveoJgAzd6nxf0Ek559292 rogid:8xFMuEva7leVYDKg3WOmvPtRTFk559292 intact-crc:D2580BF8CD75AE44|rigid:x8UnFJ+H571Pf8VTl5pHZhWXDdk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41807 uniprotkb:P37296 intact:EBI-20281|uniprotkb:D6W446|ensemblfungi:YPR036W intact:EBI-18479|uniprotkb:D6VZM9|ensemblfungi:YMR054W psi-mi:vath_yeast(display_long)|uniprotkb:YP3085.02(orf name)|uniprotkb:VMA13(gene name)|psi-mi:VMA13(display_short)|uniprotkb:CLS11(gene name synonym)|uniprotkb:YPR036W(locus name)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 54 kDa subunit(gene name synonym) psi-mi:stv1_yeast(display_long)|uniprotkb:STV1(gene name)|psi-mi:STV1(display_short)|uniprotkb:YMR054W(locus name)|uniprotkb:YM9796.07(orf name)|uniprotkb:V-ATPase 101 kDa subunit(gene name synonym)|uniprotkb:V-ATPase subunit AC115(gene name synonym)|uniprotkb:Similar to VPH1 protein 1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase subunit a 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326662|imex:IM-14275-1159 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015361.1|sgd:S000006240|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|rcsb pdb:1HO8|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YPR036W(gene)|ensemblfungi:YPR036W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|dip:DIP-6640N|mint:P41807 refseq:NP_013770.1|sgd:S000004658|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|rcsb pdb:6O7U|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YMR054W(gene)|ensemblfungi:YMR054W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|dip:DIP-4450N|mint:P37296 psi-mi:"MI:0469"(intact) crc64:54131FF9C2C87594 - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2017/08/08 rogid:kEXWvOsnTk0WdgGOny+mufz4lTo559292 rogid:gqntHtP6AtAjACy5Az0QpXAfL10559292 intact-crc:260E37F8F4CE29B1|rigid:BU9/3f50fTmTbmQ8t8HFUpN8yec false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37370 uniprotkb:P32790 intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326673|imex:IM-14275-1160 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370 refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790 psi-mi:"MI:0469"(intact) crc64:24C7522D5B1CA1C8 crc64:7FD85AA776407624 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292 intact-crc:095021E922DAE0C1|rigid:+GCwhojiHt+0QKjavWhP7pPFhog false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37370 uniprotkb:P37370 intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326684|imex:IM-14275-1161 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370 refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370 psi-mi:"MI:0469"(intact) crc64:24C7522D5B1CA1C8 crc64:24C7522D5B1CA1C8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 intact-crc:D1670D3402C1EE72|rigid:+i2ZZ2LR1rv2VmSdS4O4X7IAlhY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37370 uniprotkb:P38328 intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326695|imex:IM-14275-1162 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370 sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:24C7522D5B1CA1C8 crc64:D75C6BB8EC35EEDF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 intact-crc:6B48354174B9FA24|rigid:2iqeWAMVUsbvcBhFONcgKsNTU/0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37370 uniprotkb:P38822 intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C intact:EBI-3889|uniprotkb:E9P8V2|uniprotkb:D3DL64|ensemblfungi:YHR114W psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:bzz1_yeast(display_long)|uniprotkb:BZZ1(gene name)|psi-mi:BZZ1(display_short)|uniprotkb:LAS17-binding protein 7(gene name synonym)|uniprotkb:LSB7(gene name synonym)|uniprotkb:YHR114W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326706|imex:IM-14275-1163 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370 refseq:NP_011982.1|sgd:S000001156|dip:DIP-2143N|mint:P38822|ensemblfungi:YHR114W(gene)|ensemblfungi:YHR114W_mRNA(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009651"(response to salt stress)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:1ZUU|rcsb pdb:2A28|reactome:R-SCE-8856828|reactome:R-SCE-9013406|reactome:R-SCE-9696270 psi-mi:"MI:0469"(intact) crc64:24C7522D5B1CA1C8 crc64:5C73DACC69611B41 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 rogid:lnoTdZ+pWCE2mDz3Ha7VQOOCfM8559292 intact-crc:128B673F54A8F594|rigid:G+0A3cuELT75IoFLoR2iZ2u5Pb4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37370 uniprotkb:P39013 intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C intact:EBI-6460|intact:EBI-33854|intact:EBI-30557|intact:EBI-31021|uniprotkb:D6W195|uniprotkb:Q8TFC4|uniprotkb:Q8TFD0|uniprotkb:Q8TG51|ensemblfungi:YNL084C psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:end3_yeast(display_long)|uniprotkb:END3(gene name)|psi-mi:END3(display_short)|uniprotkb:YNL084C(locus name)|uniprotkb:N2307(orf name)|uniprotkb:Endocytosis protein 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326717|imex:IM-14275-1164 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370 refseq:NP_014315.1|sgd:S000005028|mint:P39013|dip:DIP-2220N|ensemblfungi:YNL084C(gene)|ensemblfungi:YNL084C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0071944"(cell periphery)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR025604|reactome:R-SCE-416482|reactome:R-SCE-8856828|reactome:R-SCE-9013148|reactome:R-SCE-9013406 psi-mi:"MI:0469"(intact) crc64:24C7522D5B1CA1C8 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 rogid:AvVFZdzX/4DkLet/+FGA8KrKfCw559292 intact-crc:1BE70B93FB08BEA5|rigid:2Kml3OCU2x8WAMPD9mhb7lw+w6A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40518 uniprotkb:P37370 intact:EBI-2750|uniprotkb:D6VVM2|ensemblfungi:YIL062C intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C psi-mi:arpc5_yeast(display_long)|uniprotkb:ARC15(gene name)|psi-mi:ARC15(display_short)|uniprotkb:Arp2/3 complex 16 kDa subunit(gene name synonym)|uniprotkb:YIL062C(locus name) psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326728|imex:IM-14275-1165 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012202.1|sgd:S000001324|dip:DIP-2101N|mint:P40518|ensemblfungi:YIL062C(gene)|ensemblfungi:YIL062C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR036743|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-6798695|reactome:R-SCE-8856828 refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370 psi-mi:"MI:0469"(intact) crc64:10E4DAF0F0801B02 crc64:24C7522D5B1CA1C8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iQ0mLisINMjXPulrRyDmrLcdpzU559292 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 intact-crc:333B898172753A22|rigid:0eqiFL46T+5jeVZHmHv7077qWeE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53731 uniprotkb:P37370 intact:EBI-2770|uniprotkb:D6W1L1|ensemblfungi:YNR035C intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C psi-mi:arpc2_yeast(display_long)|uniprotkb:ARC35(gene name)|psi-mi:ARC35(display_short)|uniprotkb:YNR035C(locus name)|uniprotkb:N3296(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym) psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326739|imex:IM-14275-1166 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014433.1|sgd:S000005318|dip:DIP-2304N|mint:P53731|ensemblfungi:YNR035C(gene)|ensemblfungi:YNR035C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072697"(protein localization to cell cortex)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370 psi-mi:"MI:0469"(intact) crc64:9AF71A93688729F6 crc64:24C7522D5B1CA1C8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:URdgP2srz1O44fNGQh18L7bzC+c559292 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 intact-crc:7C795A43B68054CD|rigid:NpzTg5Yuqv9lpAMW2zUheETtvM8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04439 uniprotkb:P37370 intact:EBI-11687|ensemblfungi:YMR109W|uniprotkb:D6VZT2 intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C psi-mi:myo5_yeast(display_long)|uniprotkb:MYO5(gene name)|psi-mi:MYO5(display_short)|uniprotkb:YMR109W(locus name)|uniprotkb:YM9718.08(orf name)|uniprotkb:Class I unconventional myosin MYO5(gene name synonym)|uniprotkb:Type I myosin MYO5(gene name synonym)|uniprotkb:Actin-dependent myosin-I MYO5(gene name synonym) psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326750|imex:IM-14275-1167 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR109W_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0009651"(response to salt stress)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051286"(cell tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071944"(cell periphery)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035535|ensemblfungi:YMR109W(gene)|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|rcsb pdb:1YP5|rcsb pdb:1ZUY|refseq:NP_013827.1|sgd:S000004715|mint:Q04439|dip:DIP-2222N refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370 psi-mi:"MI:0469"(intact) crc64:DFFB9EC16B61CD29 crc64:24C7522D5B1CA1C8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:n/Po/L9Xd7LP+fY39QaqP/s5US4559292 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 intact-crc:6BBEF88CDB7BA43A|rigid:8rifUtjHPNUB2wU6+PqBPByzH6g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05933 uniprotkb:P37370 intact:EBI-2764|uniprotkb:D6VZ07|ensemblfungi:YLR370C intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C psi-mi:arpc3_yeast(display_long)|uniprotkb:ARC18(gene name)|psi-mi:ARC18(display_short)|uniprotkb:YLR370C(locus name)|uniprotkb:L8039.15(orf name)|uniprotkb:Arp2/3 complex 21 kDa subunit(gene name synonym) psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326761|imex:IM-14275-1168 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004362|refseq:NP_013474.3|dip:DIP-2218N|mint:Q05933|ensemblfungi:YLR370C(gene)|ensemblfungi:YLR370C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR007204(ARP2/3 complex, 21 kDa p21-Arc subunit)|interpro:IPR036753|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370 psi-mi:"MI:0469"(intact) crc64:456EABC2B9CC4860 crc64:24C7522D5B1CA1C8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Fj4cwULcw1TK5uS1lJczcNc5gns559292 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 intact-crc:3E253A3B78B55196|rigid:9KrU/sQxJ25aWpk74b6E0XA0jK4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37370 uniprotkb:Q12446 intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326772|imex:IM-14275-1169 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370 refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446 psi-mi:"MI:0469"(intact) crc64:24C7522D5B1CA1C8 crc64:4488355563AA2645 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292 intact-crc:CEABE7EE366EDF52|rigid:bAf9x93U4M05M4QEALXeNq/9ng4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38009 uniprotkb:P32610 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326783|imex:IM-14275-1170 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610 psi-mi:"MI:0469"(intact) crc64:8ABA71761B512242 crc64:FDE93E1FAF0AEC5B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292 intact-crc:9A6DE16705985DD8|rigid:Tmv2IwT1x9Y9iAuWBVUuP0SSdsQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38009 uniprotkb:P38009 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326794|imex:IM-14275-1171 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N psi-mi:"MI:0469"(intact) crc64:8ABA71761B512242 crc64:8ABA71761B512242 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 intact-crc:2FA4F8B449E6E918|rigid:S5Uqloc7FTaA5w61fyDbN4VsnFQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38009 uniprotkb:P41811 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326805|imex:IM-14275-1172 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:8ABA71761B512242 crc64:6A5E50BBEB02CB58 figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:CE757132F62DE6BB|rigid:lG98te7ZDGDK4Bdqi7StZqtNivc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38009 uniprotkb:P53852 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 intact:EBI-29230|uniprotkb:D6W0U6|ensemblfungi:YNL247W psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:syc_yeast(display_long)|uniprotkb:Cysteinyl-tRNA synthetase(gene name synonym)|uniprotkb:N0885(orf name)|uniprotkb:YNL247W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326816|imex:IM-14275-1173 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N interpro:IPR024909|refseq:NP_014152.1|sgd:S000005191|interpro:IPR015803(Cysteinyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR032678|mint:P53852|ensemblfungi:YNL247W(gene)|ensemblfungi:YNL247W_mRNA(transcript)|go:"GO:0004817"(cysteine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006423"(cysteinyl-tRNA aminoacylation)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) crc64:8ABA71761B512242 - figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 rogid:yNdPUrnNWXwsHCz54YW9uNn9T8o559292 intact-crc:155432EA2CB99252|rigid:E8fLOJxiDHkQArr2wP3G0USxz3U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38009 uniprotkb:P54113 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 intact:EBI-14213|uniprotkb:E9PAG6|ensemblfungi:YLR028C|uniprotkb:D6VY30 psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:pur91_yeast(display_long)|uniprotkb:ADE16(gene name)|psi-mi:ADE16(display_short)|uniprotkb:YLR028C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326827|imex:IM-14275-1174 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N mint:P54113|refseq:NP_013128.1|sgd:S000004018|ensemblfungi:YLR028C(gene)|ensemblfungi:YLR028C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|interpro:IPR036914|dip:DIP-4657N psi-mi:"MI:0469"(intact) crc64:8ABA71761B512242 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 rogid:SbZvY+c2tg098pE/sezKQp+3cFE559292 intact-crc:A4761D1FED4CE5D0|rigid:4p+2fbkcYZWPnZ/Hz+TVa+/s+Xw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54783 uniprotkb:P38009 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326838|imex:IM-14275-1175 author score:99.32 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N psi-mi:"MI:0469"(intact) - crc64:8ABA71761B512242 figure legend:tables S3 and S4|author-confidence:99.32|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 intact-crc:8C30CF0BC0926F45|rigid:PznQZZxaBwdhUqJvkw8Avp0+Or8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38041 uniprotkb:P29366 intact:EBI-3719|uniprotkb:D6VPR9|ensemblfungi:YBL085W intact:EBI-3508|uniprotkb:D6VQJ6|ensemblfungi:YBR200W psi-mi:bob1_yeast(display_long)|uniprotkb:BOI1(gene name)|psi-mi:BOI1(display_short)|uniprotkb:BOB1(gene name synonym)|uniprotkb:YBL085W(locus name)|uniprotkb:YBL0717(orf name)|uniprotkb:GIN7(gene name synonym)|uniprotkb:Growth inhibitory protein 7(gene name synonym)|uniprotkb:BEM1-binding protein(gene name synonym) psi-mi:bem1_yeast(display_long)|uniprotkb:Suppressor of RHO3 protein 1(gene name synonym)|uniprotkb:BEM1(gene name)|psi-mi:BEM1(display_short)|uniprotkb:SRO1(gene name synonym)|uniprotkb:YBR200W(locus name)|uniprotkb:YBR1412(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326849|imex:IM-14275-1176 author score:87.93 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009468.1|sgd:S000000181|dip:DIP-2226N|mint:P38041|ensemblfungi:YBL085W(gene)|ensemblfungi:YBL085W_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0001881"(receptor recycling)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007015"(actin filament organization)|go:"GO:0007032"(endosome organization)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0030427"(site of polarized growth)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043332"(mating projection tip)|go:"GO:0055037"(recycling endosome)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR035551|interpro:IPR036028 sgd:S000000404|refseq:NP_009759.3|dip:DIP-688N|mint:P29366|ensemblfungi:YBR200W(gene)|ensemblfungi:YBR200W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030427"(site of polarized growth)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR030507|interpro:IPR035548|interpro:IPR035549|interpro:IPR035550|interpro:IPR036028|interpro:IPR036871|rcsb pdb:1IP9|rcsb pdb:1IPG|rcsb pdb:2CZO|rcsb pdb:2KFK|rcsb pdb:2RQV|rcsb pdb:2RQW|rcsb pdb:2V6V|reactome:R-SCE-5668599 psi-mi:"MI:0469"(intact) - crc64:FB6C525AE9A19181 figure legend:tables S3 and S4|author-confidence:87.93|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WcK0gGhMeNGTOtDIXkYjqtOuLl4559292 rogid:Fq7WxTviE31ivPWGJoZO5DsUcdg559292 intact-crc:BBE5D1154BBD93F4|rigid:YS98rzCoUbRLbILi8ecxNvjri24 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38063 uniprotkb:P32895 intact:EBI-9882|uniprotkb:Q9HGQ6|ensemblfungi:YBL068W|uniprotkb:D6VPT3 intact:EBI-9869|uniprotkb:D6VX20|ensemblfungi:YKL181W psi-mi:kpr4_yeast(display_long)|uniprotkb:PRS4(gene name)|psi-mi:PRS4(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 4(gene name synonym)|uniprotkb:PRPS4(gene name synonym)|uniprotkb:YBL0619(orf name)|uniprotkb:YBL068W(locus name) psi-mi:kpr1_yeast(display_long)|uniprotkb:PPS1(gene name synonym)|uniprotkb:PRP1(gene name synonym)|uniprotkb:PRPS(gene name synonym)|uniprotkb:PRPS1(gene name synonym)|uniprotkb:YKL181W(locus name)|uniprotkb:PRS1(gene name)|psi-mi:PRS1(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326860|imex:IM-14275-1177 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000164|refseq:NP_009485.3|ensemblfungi:YBL068W(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|ensemblfungi:YBL068W_mRNA(transcript)|dip:DIP-3945N|mint:P38063 refseq:NP_012740.1|sgd:S000001664|ensemblfungi:YKL181W(gene)|ensemblfungi:YKL181W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|dip:DIP-4857N|mint:P32895 psi-mi:"MI:0469"(intact) crc64:B6335D5F1AB1A93C crc64:F3E93ACB25E703FF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:elJfRIX/HKbgBlsUI0swFmGheuc559292 rogid:Ea45pOje4sjYrrU7ze4Af443yDk559292 intact-crc:B0067636D8447B42|rigid:JcLZMvF3mRWHRx6xuBTQJd+shq8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38620 uniprotkb:P38063 intact:EBI-9873|uniprotkb:D3DM06|ensemblfungi:YER099C intact:EBI-9882|uniprotkb:Q9HGQ6|ensemblfungi:YBL068W|uniprotkb:D6VPT3 psi-mi:kpr2_yeast(display_long)|uniprotkb:PRPS2(gene name synonym)|uniprotkb:PRS(gene name synonym)|uniprotkb:YER099C(locus name)|uniprotkb:PRS2(gene name)|psi-mi:PRS2(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 2(gene name synonym) psi-mi:kpr4_yeast(display_long)|uniprotkb:PRS4(gene name)|psi-mi:PRS4(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 4(gene name synonym)|uniprotkb:PRPS4(gene name synonym)|uniprotkb:YBL0619(orf name)|uniprotkb:YBL068W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326871|imex:IM-14275-1178 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000901|ensemblfungi:YER099C(gene)|ensemblfungi:YER099C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|refseq:NP_011025.3|dip:DIP-1482N|mint:P38620 sgd:S000000164|refseq:NP_009485.3|ensemblfungi:YBL068W(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|ensemblfungi:YBL068W_mRNA(transcript)|dip:DIP-3945N|mint:P38063 psi-mi:"MI:0469"(intact) crc64:8B970E98084F5D71 crc64:B6335D5F1AB1A93C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:yDbNtDKkeTanVZwDAftGG9nhQCE559292 rogid:elJfRIX/HKbgBlsUI0swFmGheuc559292 intact-crc:D5CB190FBF9F96AB|rigid:0fk9Nt4pPozrzQOITcIGPF1MtOw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38066 uniprotkb:P38066 intact:EBI-7436|uniprotkb:D6VPW6|ensemblfungi:YBL033C intact:EBI-7436|uniprotkb:D6VPW6|ensemblfungi:YBL033C psi-mi:rib1_yeast(display_long)|uniprotkb:RIB1(gene name)|psi-mi:RIB1(display_short)|uniprotkb:YBL033C(locus name)|uniprotkb:YBL0417(orf name)|uniprotkb:GTP cyclohydrolase II(gene name synonym) psi-mi:rib1_yeast(display_long)|uniprotkb:RIB1(gene name)|psi-mi:RIB1(display_short)|uniprotkb:YBL033C(locus name)|uniprotkb:YBL0417(orf name)|uniprotkb:GTP cyclohydrolase II(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326882|imex:IM-14275-1179 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009520.1|sgd:S000000129|mint:P38066|dip:DIP-3936N|ensemblfungi:YBL033C(gene)|ensemblfungi:YBL033C_mRNA(transcript)|go:"GO:0003935"(GTP cyclohydrolase II activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0009060"(aerobic respiration)|go:"GO:0009231"(riboflavin biosynthetic process)|go:"GO:0019238"(cyclohydrolase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000926(GTP cyclohydrolase II)|interpro:IPR032677|interpro:IPR036144 refseq:NP_009520.1|sgd:S000000129|mint:P38066|dip:DIP-3936N|ensemblfungi:YBL033C(gene)|ensemblfungi:YBL033C_mRNA(transcript)|go:"GO:0003935"(GTP cyclohydrolase II activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0009060"(aerobic respiration)|go:"GO:0009231"(riboflavin biosynthetic process)|go:"GO:0019238"(cyclohydrolase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000926(GTP cyclohydrolase II)|interpro:IPR032677|interpro:IPR036144 psi-mi:"MI:0469"(intact) crc64:D98D561CEB21A7D1 crc64:D98D561CEB21A7D1 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AvltaHA637IVn0g5TXinjIU58q0559292 rogid:AvltaHA637IVn0g5TXinjIU58q0559292 intact-crc:37C40677897AA75B|rigid:kWlAlQJZahyeNzu3fSvtyxQtL3Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38067 uniprotkb:P36017 intact:EBI-20027|uniprotkb:E9PAD1|uniprotkb:D6VQ07|ensemblfungi:YBR006W intact:EBI-29399|uniprotkb:D6W2F0|ensemblfungi:YOR089C psi-mi:uga2_yeast(display_long)|uniprotkb:UGA2(gene name)|psi-mi:UGA2(display_short)|uniprotkb:UGA5(gene name synonym)|uniprotkb:YBR006W(locus name)|uniprotkb:YBR0112(orf name) psi-mi:vps21_yeast(display_long)|uniprotkb:GTP-binding protein YPT51(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 12(gene name synonym)|uniprotkb:VPS21(gene name)|psi-mi:VPS21(display_short)|uniprotkb:YOR089C(locus name)|uniprotkb:YOR3154C(orf name)|uniprotkb:VPS12(gene name synonym)|uniprotkb:VPT12(gene name synonym)|uniprotkb:YPT21(gene name synonym)|uniprotkb:YPT51(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326893|imex:IM-14275-1180 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009560.1|sgd:S000000210|ensemblfungi:YBR006W(gene)|ensemblfungi:YBR006W_mRNA(transcript)|go:"GO:0004777"("succinate-semialdehyde dehydrogenase (NAD+) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0006540"(glutamate decarboxylation to succinate)|go:"GO:0009013"("succinate-semialdehyde dehydrogenase [NAD(P)+] activity")|go:"GO:0009450"(gamma-aminobutyric acid catabolic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036243"("succinate-semialdehyde dehydrogenase (NADP+) activity")|interpro:IPR010102(Succinic semialdehyde dehydrogenase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|reactome:R-SCE-916853|dip:DIP-1759N|mint:P38067 refseq:NP_014732.1|sgd:S000005615|dip:DIP-3801N|mint:P36017|ensemblfungi:YOR089C(gene)|ensemblfungi:YOR089C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0061709"(reticulophagy)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1EK0 psi-mi:"MI:0469"(intact) - crc64:34D7DA0090C33F09 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:NVgDIuepoPrbu9KfXF7Ve3tZ2UM559292 rogid:fo/U32XQLnHSVpuK48jddD4Kve4559292 intact-crc:376AEF2310A8076E|rigid:ZBRN7k+UBRrkWNhcPJNM8xKg+aY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:P38084 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-3414|uniprotkb:D6VQ67|ensemblfungi:YBR068C psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:bap2_yeast(display_long)|uniprotkb:Branched-chain amino-acid permease 2(gene name synonym)|uniprotkb:BAP2(gene name)|psi-mi:BAP2(display_short)|uniprotkb:YBR068C(locus name)|uniprotkb:YBR0629(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326915|imex:IM-14275-1182 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N sgd:S000000272|refseq:NP_009624.4|dip:DIP-4910N|mint:P38084|ensemblfungi:YBR068C(gene)|ensemblfungi:YBR068C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015192"(L-phenylalanine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098713"(leucine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) psi-mi:"MI:0469"(intact) - crc64:B87FD6A7464E07F5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:7Fw7+M5mBikZBztHE2tSDpvBi/M559292 intact-crc:38FC95A7FE94C5FA|rigid:2bySjv1UyREoKxA6yuTF5DVsXT4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38067 uniprotkb:P38067 intact:EBI-20027|uniprotkb:E9PAD1|uniprotkb:D6VQ07|ensemblfungi:YBR006W intact:EBI-20027|uniprotkb:E9PAD1|uniprotkb:D6VQ07|ensemblfungi:YBR006W psi-mi:uga2_yeast(display_long)|uniprotkb:UGA2(gene name)|psi-mi:UGA2(display_short)|uniprotkb:UGA5(gene name synonym)|uniprotkb:YBR006W(locus name)|uniprotkb:YBR0112(orf name) psi-mi:uga2_yeast(display_long)|uniprotkb:UGA2(gene name)|psi-mi:UGA2(display_short)|uniprotkb:UGA5(gene name synonym)|uniprotkb:YBR006W(locus name)|uniprotkb:YBR0112(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326904|imex:IM-14275-1181 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009560.1|sgd:S000000210|ensemblfungi:YBR006W(gene)|ensemblfungi:YBR006W_mRNA(transcript)|go:"GO:0004777"("succinate-semialdehyde dehydrogenase (NAD+) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0006540"(glutamate decarboxylation to succinate)|go:"GO:0009013"("succinate-semialdehyde dehydrogenase [NAD(P)+] activity")|go:"GO:0009450"(gamma-aminobutyric acid catabolic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036243"("succinate-semialdehyde dehydrogenase (NADP+) activity")|interpro:IPR010102(Succinic semialdehyde dehydrogenase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|reactome:R-SCE-916853|dip:DIP-1759N|mint:P38067 refseq:NP_009560.1|sgd:S000000210|ensemblfungi:YBR006W(gene)|ensemblfungi:YBR006W_mRNA(transcript)|go:"GO:0004777"("succinate-semialdehyde dehydrogenase (NAD+) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0006540"(glutamate decarboxylation to succinate)|go:"GO:0009013"("succinate-semialdehyde dehydrogenase [NAD(P)+] activity")|go:"GO:0009450"(gamma-aminobutyric acid catabolic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036243"("succinate-semialdehyde dehydrogenase (NADP+) activity")|interpro:IPR010102(Succinic semialdehyde dehydrogenase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|reactome:R-SCE-916853|dip:DIP-1759N|mint:P38067 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:NVgDIuepoPrbu9KfXF7Ve3tZ2UM559292 rogid:NVgDIuepoPrbu9KfXF7Ve3tZ2UM559292 intact-crc:A97D0D5511F7614D|rigid:HkYx59QBHrUQkjnVtQ2dEyc59dw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38084 uniprotkb:Q02774 intact:EBI-3414|uniprotkb:D6VQ67|ensemblfungi:YBR068C intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 psi-mi:bap2_yeast(display_long)|uniprotkb:Branched-chain amino-acid permease 2(gene name synonym)|uniprotkb:BAP2(gene name)|psi-mi:BAP2(display_short)|uniprotkb:YBR068C(locus name)|uniprotkb:YBR0629(orf name) psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326926|imex:IM-14275-1183 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000272|refseq:NP_009624.4|dip:DIP-4910N|mint:P38084|ensemblfungi:YBR068C(gene)|ensemblfungi:YBR068C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015192"(L-phenylalanine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098713"(leucine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 psi-mi:"MI:0469"(intact) crc64:B87FD6A7464E07F5 - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:7Fw7+M5mBikZBztHE2tSDpvBi/M559292 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 intact-crc:CC3433C89A092673|rigid:LyYFUdA2k0VxpUCwq2yPxKHUuyI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38089 uniprotkb:Q12133 intact:EBI-12814|uniprotkb:D6VQC2|ensemblfungi:YBR125C intact:EBI-17829|uniprotkb:D6VY67|ensemblfungi:YLR066W psi-mi:pp2c4_yeast(display_long)|uniprotkb:PTC4(gene name)|psi-mi:PTC4(display_short)|uniprotkb:GCT1(gene name synonym)|uniprotkb:YBR125C(locus name)|uniprotkb:YBR0921(orf name) psi-mi:spc3_yeast(display_long)|uniprotkb:SPC3(gene name)|psi-mi:SPC3(display_short)|uniprotkb:YLR066W(locus name)|uniprotkb:L2186(orf name)|uniprotkb:Microsomal signal peptidase subunit 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326937|imex:IM-14275-1184 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBR125C(gene)|ensemblfungi:YBR125C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C, manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|refseq:NP_009683.1|sgd:S000000329|mint:P38089|dip:DIP-6437N sgd:S000004056|refseq:NP_013167.1|ensemblfungi:YLR066W(gene)|ensemblfungi:YLR066W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR007653(Signal peptidase 22 kDa subunit)|dip:DIP-5083N|mint:Q12133 psi-mi:"MI:0469"(intact) crc64:27F2903048541B6A - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wsO0ow/17y+DskxpeuZ3CG8ou9g559292 rogid:Yo9d2WsA1GUlNLc0oSPZhYk+fvs559292 intact-crc:886D9A323D6D80E1|rigid:RnGElpt6qHkKSF2h/68G5Jd02CM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38090 uniprotkb:P38234 intact:EBI-2362|uniprotkb:D6VQC9|ensemblfungi:YBR132C intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C psi-mi:agp2_yeast(display_long)|uniprotkb:AGP2(gene name)|psi-mi:AGP2(display_short)|uniprotkb:YBR1007(orf name)|uniprotkb:YBR132C(locus name) psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326948|imex:IM-14275-1185 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009690.1|sgd:S000000336|dip:DIP-8141N|mint:P38090|ensemblfungi:YBR132C(gene)|ensemblfungi:YBR132C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:1902269"(positive regulation of polyamine transmembrane transport)|go:"GO:1902274"("positive regulation of (R)-carnitine transmembrane transport")|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SQ0XmZP6PWuNCjgiQs2JkcI0RzA559292 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 intact-crc:E31AF275DFA084BA|rigid:ViLuZbJ8IxWp92S66EYflCiUV9Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38090 uniprotkb:P38929 intact:EBI-2362|uniprotkb:D6VQC9|ensemblfungi:YBR132C intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W psi-mi:agp2_yeast(display_long)|uniprotkb:AGP2(gene name)|psi-mi:AGP2(display_short)|uniprotkb:YBR1007(orf name)|uniprotkb:YBR132C(locus name) psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326959|imex:IM-14275-1186 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009690.1|sgd:S000000336|dip:DIP-8141N|mint:P38090|ensemblfungi:YBR132C(gene)|ensemblfungi:YBR132C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:1902269"(positive regulation of polyamine transmembrane transport)|go:"GO:1902274"("positive regulation of (R)-carnitine transmembrane transport")|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 psi-mi:"MI:0469"(intact) - crc64:5BD9ECFF8508F396 figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SQ0XmZP6PWuNCjgiQs2JkcI0RzA559292 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 intact-crc:55AFEF822879E4FA|rigid:yWgrxGyIKhk1mrRUEbkJIJ0wx0s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38126 uniprotkb:P38985 intact:EBI-12989|uniprotkb:D6VQI1|ensemblfungi:YBR186W intact:EBI-17977|uniprotkb:D6VRQ6|ensemblfungi:YDL092W psi-mi:pch2_yeast(display_long)|uniprotkb:YBR1308(orf name)|uniprotkb:YBR186W(locus name)|uniprotkb:PCH2(gene name)|psi-mi:PCH2(display_short) psi-mi:srp14_yeast(display_long)|uniprotkb:SRP14(gene name)|psi-mi:SRP14(display_short)|uniprotkb:YDL092W(locus name)|uniprotkb:D2404(orf name)|uniprotkb:Signal recognition particle 14 kDa protein homolog(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326970|imex:IM-14275-1187 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009745.2|sgd:S000000390|ensemblfungi:YBR186W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR027417|interpro:IPR044539|ensemblfungi:YBR186W(gene)|mint:P38126|dip:DIP-4661N refseq:NP_010191.1|sgd:S000002250|ensemblfungi:YDL092W(gene)|ensemblfungi:YDL092W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR003210(Signal recognition particle, SRP14 subunit)|interpro:IPR009018(Signal recognition particle, SRP9/SRP14 subunit)|reactome:R-SCE-1799339|reactome:R-SCE-6798695|dip:DIP-4864N|mint:P38985 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vzBEe5F/t0xRgnYrv22ZujXwAgs559292 rogid:I9myDFdKPRnrKsHBhWBxI/Em7EQ559292 intact-crc:7C8383AF4A538FDF|rigid:sJ7NKEqqyQ/66l0s3KA7KXBRn+k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38137 uniprotkb:P38137 intact:EBI-6831|uniprotkb:D6VQL9|ensemblfungi:YBR222C intact:EBI-6831|uniprotkb:D6VQL9|ensemblfungi:YBR222C psi-mi:fat2_yeast(display_long)|uniprotkb:PCS60(gene name)|psi-mi:PCS60(display_short)|uniprotkb:FAT2(gene name synonym)|uniprotkb:AAE3(gene name synonym)|uniprotkb:Acyl-activating enzyme 3(gene name synonym)|uniprotkb:Oxalyl-CoA synthetase(gene name synonym)|uniprotkb:Peroxisomal-coenzyme A synthetase(gene name synonym)|uniprotkb:YBR1512(orf name)|uniprotkb:YBR222C(locus name) psi-mi:fat2_yeast(display_long)|uniprotkb:PCS60(gene name)|psi-mi:PCS60(display_short)|uniprotkb:FAT2(gene name synonym)|uniprotkb:AAE3(gene name synonym)|uniprotkb:Acyl-activating enzyme 3(gene name synonym)|uniprotkb:Oxalyl-CoA synthetase(gene name synonym)|uniprotkb:Peroxisomal-coenzyme A synthetase(gene name synonym)|uniprotkb:YBR1512(orf name)|uniprotkb:YBR222C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326981|imex:IM-14275-1188 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009781.3|sgd:S000000426|mint:P38137|dip:DIP-2796N|ensemblfungi:YBR222C(gene)|ensemblfungi:YBR222C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0033611"(oxalate catabolic process)|go:"GO:0050203"(oxalate-CoA ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR042099 refseq:NP_009781.3|sgd:S000000426|mint:P38137|dip:DIP-2796N|ensemblfungi:YBR222C(gene)|ensemblfungi:YBR222C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0033611"(oxalate catabolic process)|go:"GO:0050203"(oxalate-CoA ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR042099 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aG/jj32v1+BQAZbQ1bM59QnQca0559292 rogid:aG/jj32v1+BQAZbQ1bM59QnQca0559292 intact-crc:7E076ECBB22F431E|rigid:MSE2N8JjJqCKLWY+eBj6Y9SQ7RY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38143 uniprotkb:P19807 intact:EBI-7863|uniprotkb:D6VQP0|ensemblfungi:YBR244W intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:gpx2_yeast(display_long)|uniprotkb:GPX2(gene name)|psi-mi:GPX2(display_short)|uniprotkb:Glutathione peroxidase homolog 2(gene name synonym)|uniprotkb:YBR1632(orf name)|uniprotkb:YBR244W(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6326992|imex:IM-14275-1189 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000448|refseq:NP_009803.3|mint:P38143|dip:DIP-8180N|ensemblfungi:YBR244W(gene)|ensemblfungi:YBR244W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR029759|interpro:IPR029760|interpro:IPR036249|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cL8rm6IttRi0QYzWVEooubWkZN8559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:7D0EEE35068C1BF1|rigid:Sp3zh3gE8dEnz1E1w6VVuscLXTQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P38143 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-7863|uniprotkb:D6VQP0|ensemblfungi:YBR244W psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:gpx2_yeast(display_long)|uniprotkb:GPX2(gene name)|psi-mi:GPX2(display_short)|uniprotkb:Glutathione peroxidase homolog 2(gene name synonym)|uniprotkb:YBR1632(orf name)|uniprotkb:YBR244W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327003|imex:IM-14275-1190 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 sgd:S000000448|refseq:NP_009803.3|mint:P38143|dip:DIP-8180N|ensemblfungi:YBR244W(gene)|ensemblfungi:YBR244W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR029759|interpro:IPR029760|interpro:IPR036249|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:cL8rm6IttRi0QYzWVEooubWkZN8559292 intact-crc:B62DFA6EB3824F6A|rigid:VFo1Aa3lYdHEpQqwv/+4fQYGGFA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38234 uniprotkb:P38143 intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C intact:EBI-7863|uniprotkb:D6VQP0|ensemblfungi:YBR244W psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:gpx2_yeast(display_long)|uniprotkb:GPX2(gene name)|psi-mi:GPX2(display_short)|uniprotkb:Glutathione peroxidase homolog 2(gene name synonym)|uniprotkb:YBR1632(orf name)|uniprotkb:YBR244W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327014|imex:IM-14275-1191 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 sgd:S000000448|refseq:NP_009803.3|mint:P38143|dip:DIP-8180N|ensemblfungi:YBR244W(gene)|ensemblfungi:YBR244W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR029759|interpro:IPR029760|interpro:IPR036249|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 rogid:cL8rm6IttRi0QYzWVEooubWkZN8559292 intact-crc:571893782B8DC23E|rigid:D75V9qwN54Eds6sovSBSuAz8ZN8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38143 uniprotkb:P50276 intact:EBI-7863|uniprotkb:D6VQP0|ensemblfungi:YBR244W intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:gpx2_yeast(display_long)|uniprotkb:GPX2(gene name)|psi-mi:GPX2(display_short)|uniprotkb:Glutathione peroxidase homolog 2(gene name synonym)|uniprotkb:YBR1632(orf name)|uniprotkb:YBR244W(locus name) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327025|imex:IM-14275-1192 author score:95.85 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000448|refseq:NP_009803.3|mint:P38143|dip:DIP-8180N|ensemblfungi:YBR244W(gene)|ensemblfungi:YBR244W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR029759|interpro:IPR029760|interpro:IPR036249|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661 ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:95.85|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cL8rm6IttRi0QYzWVEooubWkZN8559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:E4881582FA7DA415|rigid:XuJIdQXXalN3G4aZFmHKUcCthyA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38143 uniprotkb:Q02785 intact:EBI-7863|uniprotkb:D6VQP0|ensemblfungi:YBR244W intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:gpx2_yeast(display_long)|uniprotkb:GPX2(gene name)|psi-mi:GPX2(display_short)|uniprotkb:Glutathione peroxidase homolog 2(gene name synonym)|uniprotkb:YBR1632(orf name)|uniprotkb:YBR244W(locus name) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327036|imex:IM-14275-1193 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000448|refseq:NP_009803.3|mint:P38143|dip:DIP-8180N|ensemblfungi:YBR244W(gene)|ensemblfungi:YBR244W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR029759|interpro:IPR029760|interpro:IPR036249|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661 refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cL8rm6IttRi0QYzWVEooubWkZN8559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:808DBC49795D495A|rigid:yBA4zSDm3j2NxMnbQkx8WSytP6s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38143 uniprotkb:Q06451 intact:EBI-7863|uniprotkb:D6VQP0|ensemblfungi:YBR244W intact:EBI-34275|uniprotkb:D6W4F2|ensemblfungi:YPR156C psi-mi:gpx2_yeast(display_long)|uniprotkb:GPX2(gene name)|psi-mi:GPX2(display_short)|uniprotkb:Glutathione peroxidase homolog 2(gene name synonym)|uniprotkb:YBR1632(orf name)|uniprotkb:YBR244W(locus name) psi-mi:tpo3_yeast(display_long)|uniprotkb:TPO3(gene name)|psi-mi:TPO3(display_short)|uniprotkb:P9584.7(orf name)|uniprotkb:YPR156C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327047|imex:IM-14275-1194 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000448|refseq:NP_009803.3|mint:P38143|dip:DIP-8180N|ensemblfungi:YBR244W(gene)|ensemblfungi:YBR244W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR029759|interpro:IPR029760|interpro:IPR036249|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661 refseq:NP_015482.1|sgd:S000006360|mint:Q06451|dip:DIP-3907N|ensemblfungi:YPR156C(gene)|ensemblfungi:YPR156C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - crc64:D260ED161F800502 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cL8rm6IttRi0QYzWVEooubWkZN8559292 rogid:oVpx7Bjk/mK2Q7+/j05tX3gHw7k559292 intact-crc:EFBBA01A98574157|rigid:2M7qp37zbPvgjriBIvf0qFOorUg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38143 uniprotkb:Q3E756 intact:EBI-7863|uniprotkb:D6VQP0|ensemblfungi:YBR244W intact:EBI-2044812|uniprotkb:D6VPX0|ensemblfungi:YBL029C-A psi-mi:gpx2_yeast(display_long)|uniprotkb:GPX2(gene name)|psi-mi:GPX2(display_short)|uniprotkb:Glutathione peroxidase homolog 2(gene name synonym)|uniprotkb:YBR1632(orf name)|uniprotkb:YBR244W(locus name) psi-mi:yb029_yeast(display_long)|uniprotkb:YBL029C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327058|imex:IM-14275-1195 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000448|refseq:NP_009803.3|mint:P38143|dip:DIP-8180N|ensemblfungi:YBR244W(gene)|ensemblfungi:YBR244W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR029759|interpro:IPR029760|interpro:IPR036249|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661 sgd:S000007591|refseq:NP_076874.1|mint:Q3E756|ensemblfungi:YBL029C-A(gene)|ensemblfungi:YBL029C-A_mRNA(transcript)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cL8rm6IttRi0QYzWVEooubWkZN8559292 rogid:Y9LDkESr65DK5SLFNTw1dBKeqPc559292 intact-crc:E6B703F5855D28C3|rigid:sssdN3kyB0mUJLDOo4I6L8qeb8g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38145 uniprotkb:P38145 intact:EBI-2083267|uniprotkb:D6VQQ3|ensemblfungi:YBR256C intact:EBI-2083267|uniprotkb:D6VQQ3|ensemblfungi:YBR256C psi-mi:risa_yeast(display_long)|uniprotkb:RIB5(gene name)|psi-mi:RIB5(display_short)|uniprotkb:YBR1724(orf name)|uniprotkb:YBR256C(locus name) psi-mi:risa_yeast(display_long)|uniprotkb:RIB5(gene name)|psi-mi:RIB5(display_short)|uniprotkb:YBR1724(orf name)|uniprotkb:YBR256C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327069|imex:IM-14275-1196 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR026017|refseq:NP_009815.1|sgd:S000000460|interpro:IPR023366|interpro:IPR001783(Lumazine-binding protein)|interpro:IPR017938|mint:P38145|ensemblfungi:YBR256C(gene)|ensemblfungi:YBR256C_mRNA(transcript)|go:"GO:0004746"(riboflavin synthase activity)|go:"GO:0009231"(riboflavin biosynthetic process) interpro:IPR026017|refseq:NP_009815.1|sgd:S000000460|interpro:IPR023366|interpro:IPR001783(Lumazine-binding protein)|interpro:IPR017938|mint:P38145|ensemblfungi:YBR256C(gene)|ensemblfungi:YBR256C_mRNA(transcript)|go:"GO:0004746"(riboflavin synthase activity)|go:"GO:0009231"(riboflavin biosynthetic process) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iqxrSJ0JchsnNw7lYL2863A9V34559292 rogid:iqxrSJ0JchsnNw7lYL2863A9V34559292 intact-crc:A9CC57BF6EFF6E61|rigid:CWoGN6Vjkn0Uo0ZFZoOfOCNw/YY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39958 uniprotkb:P38146 intact:EBI-7517|uniprotkb:D3DM41|ensemblfungi:YER136W intact:EBI-29357|uniprotkb:D6VQR1|ensemblfungi:YBR264C psi-mi:gdi1_yeast(display_long)|uniprotkb:YER136W(locus name)|uniprotkb:GDI1(gene name)|psi-mi:GDI1(display_short)|uniprotkb:SEC19(gene name synonym)|uniprotkb:Secretory pathway GDP dissociation inhibitor(gene name synonym) psi-mi:ypt10_yeast(display_long)|uniprotkb:YPT10(gene name)|psi-mi:YPT10(display_short)|uniprotkb:YBR1733(orf name)|uniprotkb:YBR264C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327080|imex:IM-14275-1197 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011062.1|sgd:S000000938|mint:P39958|dip:DIP-785N|ensemblfungi:YER136W(gene)|ensemblfungi:YER136W_mRNA(transcript)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|rcsb pdb:1UKV|rcsb pdb:2BCG|rcsb pdb:3CPH|rcsb pdb:3CPI|rcsb pdb:3CPJ|reactome:R-SCE-6798695|reactome:R-SCE-8876198 refseq:NP_009823.2|sgd:S000000468|dip:DIP-4954N|mint:P38146|ensemblfungi:YBR264C(gene)|ensemblfungi:YBR264C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0012505"(endomembrane system)|go:"GO:0019001"(guanyl nucleotide binding)|go:"GO:0030139"(endocytic vesicle)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-SCE-6798695|reactome:R-SCE-8856828|reactome:R-SCE-8873719|reactome:R-SCE-8876198|reactome:R-SCE-983231 psi-mi:"MI:0469"(intact) crc64:48CF8D45FC031772 crc64:EE66719A8C65AA54 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AkWsG1VUBGxajiAMw0e0mOljZ6s559292 rogid:l3mQATYObyLmn6lF3I+KwOlVj1o559292 intact-crc:02333CA1F2EDEEDE|rigid:8ywiF+HmmFSfLcrsxCMAVjMezUQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38153 uniprotkb:P38153 intact:EBI-2710|uniprotkb:D6VQT3|ensemblfungi:YBR288C intact:EBI-2710|uniprotkb:D6VQT3|ensemblfungi:YBR288C psi-mi:ap3m_yeast(display_long)|uniprotkb:APM3(gene name)|psi-mi:APM3(display_short)|uniprotkb:YKS6(gene name synonym)|uniprotkb:YBR288C(locus name)|uniprotkb:YBR2035(orf name)|uniprotkb:Mu3-adaptin(gene name synonym)|uniprotkb:Mu-adaptin 3A(gene name synonym)|uniprotkb:AP-3 adaptor complex mu3A subunit(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit mu(gene name synonym) psi-mi:ap3m_yeast(display_long)|uniprotkb:APM3(gene name)|psi-mi:APM3(display_short)|uniprotkb:YKS6(gene name synonym)|uniprotkb:YBR288C(locus name)|uniprotkb:YBR2035(orf name)|uniprotkb:Mu3-adaptin(gene name synonym)|uniprotkb:Mu-adaptin 3A(gene name synonym)|uniprotkb:AP-3 adaptor complex mu3A subunit(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit mu(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327091|imex:IM-14275-1198 author score:99.36 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000492|refseq:NP_009847.4|dip:DIP-4965N|mint:P38153|ensemblfungi:YBR288C(gene)|ensemblfungi:YBR288C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR018240|interpro:IPR028565|interpro:IPR036168 sgd:S000000492|refseq:NP_009847.4|dip:DIP-4965N|mint:P38153|ensemblfungi:YBR288C(gene)|ensemblfungi:YBR288C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR018240|interpro:IPR028565|interpro:IPR036168 psi-mi:"MI:0469"(intact) crc64:AAD5A7EA305C63CF crc64:AAD5A7EA305C63CF figure legend:tables S3 and S4|author-confidence:99.36|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FGGguxVhmH8D9D+pqXCAWAGXAuY559292 rogid:FGGguxVhmH8D9D+pqXCAWAGXAuY559292 intact-crc:906176AB1F4B77D1|rigid:fzU935iSQLrxf6PfHuxZjlQyIR8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08951 uniprotkb:P38153 intact:EBI-29702|uniprotkb:Q02737|uniprotkb:Q7LIB1|uniprotkb:D6W3H3|ensemblfungi:YPL195W intact:EBI-2710|uniprotkb:D6VQT3|ensemblfungi:YBR288C psi-mi:ap3d_yeast(display_long)|uniprotkb:YPL195W(locus name)|uniprotkb:Delta-adaptin 3(gene name synonym)|uniprotkb:APL5(gene name)|psi-mi:APL5(display_short)|uniprotkb:YKS4(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit delta(gene name synonym) psi-mi:ap3m_yeast(display_long)|uniprotkb:APM3(gene name)|psi-mi:APM3(display_short)|uniprotkb:YKS6(gene name synonym)|uniprotkb:YBR288C(locus name)|uniprotkb:YBR2035(orf name)|uniprotkb:Mu3-adaptin(gene name synonym)|uniprotkb:Mu-adaptin 3A(gene name synonym)|uniprotkb:AP-3 adaptor complex mu3A subunit(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit mu(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327102|imex:IM-14275-1199 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015129.1|sgd:S000006116|dip:DIP-3977N|mint:Q08951|ensemblfungi:YPL195W(gene)|ensemblfungi:YPL195W_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030665"(clathrin-coated vesicle membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017105(Adaptor protein complex AP-3, delta subunit) sgd:S000000492|refseq:NP_009847.4|dip:DIP-4965N|mint:P38153|ensemblfungi:YBR288C(gene)|ensemblfungi:YBR288C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR018240|interpro:IPR028565|interpro:IPR036168 psi-mi:"MI:0469"(intact) crc64:51415466FF25CC40 crc64:AAD5A7EA305C63CF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mCtBXyUDDBZ4freC+1z5iPIEJTo559292 rogid:FGGguxVhmH8D9D+pqXCAWAGXAuY559292 intact-crc:E43D11B3BC0640BB|rigid:9X44Htp6RyDMUeivtcCliEx8CRI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:P38166 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327113|imex:IM-14275-1200 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166 psi-mi:"MI:0469"(intact) - crc64:1BF971749814382C figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292 intact-crc:498B0B6DA2CA8A69|rigid:yERFMIIRI0xdr5u+h049REJV8ow false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38166 uniprotkb:P11076 intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short) psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327124|imex:IM-14275-1201 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166 refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 psi-mi:"MI:0469"(intact) crc64:1BF971749814382C crc64:796859026AC63CC0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 intact-crc:1B47CA415A8CEEE6|rigid:cf4cHWA/GO8i0EOVzDwC8rHhh9Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38166 uniprotkb:P25361 intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W intact:EBI-21909|uniprotkb:D6VR52|ensemblfungi:YCR043C psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short) psi-mi:yct3_yeast(display_long)|uniprotkb:YCR43C(orf name)|uniprotkb:YCR725(orf name)|uniprotkb:YCR043C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327135|imex:IM-14275-1202 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166 sgd:S000000639|refseq:NP_009972.1|mint:P25361|ensemblfungi:YCR043C(gene)|ensemblfungi:YCR043C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0043332"(mating projection tip) psi-mi:"MI:0469"(intact) crc64:1BF971749814382C - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292 rogid:bEMtsAa5vCsWqGOiXwBK40Pa0xQ559292 intact-crc:A72AD7EBCF508BC2|rigid:8E7p9xX6fvfASuWuCqOuV2x8mtA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38166 uniprotkb:P38142 intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W intact:EBI-21079|uniprotkb:D6VQN7|intact:EBI-2347460|uniprotkb:Q6B2Y5|ensemblfungi:YBR241C psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short) psi-mi:yb91_yeast(display_long)|uniprotkb:YBR1625(orf name)|uniprotkb:YBR241C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327146|imex:IM-14275-1203 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166 refseq:NP_009800.1|sgd:S000000445|mint:P38142|dip:DIP-5363N|ensemblfungi:YBR241C(gene)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|reactome:R-SCE-189200|reactome:R-SCE-196836|reactome:R-SCE-422356|reactome:R-SCE-5653890|reactome:R-SCE-6798695|reactome:R-SCE-8981373|ensemblfungi:YBR241C_mRNA(transcript) psi-mi:"MI:0469"(intact) crc64:1BF971749814382C - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292 rogid:B0qgnhfd17hrDGLrJ21KY/FCzTQ559292 intact-crc:DD79C2E460A99960|rigid:mbeu/J4iMTqNU5XxJbEe4MCVyAI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38166 uniprotkb:P38166 intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short) psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327157|imex:IM-14275-1204 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166 ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166 psi-mi:"MI:0469"(intact) crc64:1BF971749814382C crc64:1BF971749814382C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292 rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292 intact-crc:867A38CE82583FD6|rigid:RR+H+njmHTpXJWF2hYOgfSgyrQs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38166 uniprotkb:P38310 intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327168|imex:IM-14275-1205 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166 refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) crc64:1BF971749814382C crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:BFD09259BAD47C5F|rigid:4uENdbUh1piTpT7Y4Fa8c7qjD/s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38929 uniprotkb:P38166 intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327179|imex:IM-14275-1206 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166 psi-mi:"MI:0469"(intact) crc64:5BD9ECFF8508F396 crc64:1BF971749814382C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292 intact-crc:3A6949E99591A804|rigid:tLGnEbvMqviCtQVEFyhQfJXtFcE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38166 uniprotkb:P39010 intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short) psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327190|imex:IM-14275-1207 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166 refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 psi-mi:"MI:0469"(intact) crc64:1BF971749814382C - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 intact-crc:A19C23CD1EB53466|rigid:FkLF0X66mYuMjrrKvetgVEiXA0c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40527 uniprotkb:P38166 intact:EBI-3137|uniprotkb:D6VVN3|ensemblfungi:YIL048W intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W psi-mi:atc7_yeast(display_long)|uniprotkb:NEO1(gene name)|psi-mi:NEO1(display_short)|uniprotkb:YIL048W(locus name) psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327209|imex:IM-14275-1208 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012216.1|sgd:S000001310|dip:DIP-2548N|mint:P40527|ensemblfungi:YIL048W(gene)|ensemblfungi:YIL048W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006897"(endocytosis)|go:"GO:0007033"(vacuole organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-936837 ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166 psi-mi:"MI:0469"(intact) - crc64:1BF971749814382C figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:v12VeCVbehsVpj+kjnnhKmIf9o4559292 rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292 intact-crc:598B6C0B45D527F7|rigid:GvFZfHT7DAGCzll6Hk+j5Xs5wXk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43561 uniprotkb:P38166 intact:EBI-6891|uniprotkb:D6VTI9|ensemblfungi:YFL041W intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W psi-mi:fet5_yeast(display_long)|uniprotkb:YFL041W(locus name)|uniprotkb:FET5(gene name)|psi-mi:FET5(display_short) psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327220|imex:IM-14275-1209 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116612.1|sgd:S000001853|mint:P43561|dip:DIP-6774N|ensemblfungi:YFL041W(gene)|ensemblfungi:YFL041W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006826"(iron ion transport)|go:"GO:0010106"(cellular response to iron ion starvation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0033215"(reductive iron assimilation)|go:"GO:0034755"(iron ion transmembrane transport)|interpro:IPR001117(Multicopper oxidase, type 1)|interpro:IPR002355(Multicopper oxidase, copper-binding site)|interpro:IPR008972(Cupredoxin)|interpro:IPR011706(Multicopper oxidase, type 2)|interpro:IPR011707(Multicopper oxidase, type 3)|interpro:IPR033138|interpro:IPR044130 ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166 psi-mi:"MI:0469"(intact) - crc64:1BF971749814382C figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Po/KJNFIGJj4hdCBkOxRkFEiuqI559292 rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292 intact-crc:1DA90113CA66591A|rigid:LIFGxG3KfrAkCXRCUW+0Dy7L/Do false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43621 uniprotkb:P38166 intact:EBI-4876|uniprotkb:D6VTT4|ensemblfungi:YFR051C intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W psi-mi:copd_yeast(display_long)|uniprotkb:RET2(gene name)|psi-mi:RET2(display_short)|uniprotkb:YFR051C(locus name)|uniprotkb:Delta-coat protein(gene name synonym) psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327231|imex:IM-14275-1210 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001947|refseq:NP_116709.3|dip:DIP-5255N|mint:P43621|ensemblfungi:YFR051C(gene)|ensemblfungi:YFR051C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|rcsb pdb:5FJW|rcsb pdb:5FJX|rcsb pdb:5FJZ|rcsb pdb:5FK0|reactome:R-SCE-6807878|reactome:R-SCE-6811434 ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166 psi-mi:"MI:0469"(intact) crc64:AA730F046655EE5A crc64:1BF971749814382C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:auvjuT8ffm1R4P3mRKEIWAsynW0559292 rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292 intact-crc:E92836944F9BE67F|rigid:JlIzbyFx62tfg6wvgKCbAYhCqHM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38166 uniprotkb:P46989 intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short) psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327242|imex:IM-14275-1211 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166 refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:1BF971749814382C - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 intact-crc:6BDCA22C28B9364B|rigid:+8DutP67cfYNrbIPmER+y37LdZk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38166 uniprotkb:Q03730 intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W intact:EBI-27739|uniprotkb:Q6B2K7|uniprotkb:D6VZF6|ensemblfungi:YML018C psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short) psi-mi:ymb8_yeast(display_long)|uniprotkb:YML018C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327253|imex:IM-14275-1212 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166 sgd:S000004480|refseq:NP_013694.1|dip:DIP-4953N|mint:Q03730|ensemblfungi:YML018C(gene)|ensemblfungi:YML018C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) crc64:1BF971749814382C crc64:DEC5C3EEF293F5ED figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292 rogid:4WxEFdhqbP7pcRcTLeFHljCVQ34559292 intact-crc:8CBD4A9A68D7FC12|rigid:A0c1IS7XH8H2bw8j6oOM7YLNEL4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38166 uniprotkb:Q03860 intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327264|imex:IM-14275-1213 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166 sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) crc64:1BF971749814382C crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:DEADF73ABEA60F5A|rigid:T7XAynnpE00EeDrVGnrakyh4HCw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:P38166 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327275|imex:IM-14275-1214 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166 psi-mi:"MI:0469"(intact) - crc64:1BF971749814382C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292 intact-crc:658AE285314CB24D|rigid:Wk0LrYWHVPYc5k5GbFUHW1bGL2s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38195 uniprotkb:P39005 intact:EBI-21230|uniprotkb:D6VPV5|ensemblfungi:YBL043W intact:EBI-9930|uniprotkb:D6VW14|ensemblfungi:YJL174W psi-mi:ecm13_yeast(display_long)|uniprotkb:YBL043W(locus name)|uniprotkb:YBL0405(orf name)|uniprotkb:ECM13(gene name)|psi-mi:ECM13(display_short)|uniprotkb:Extracellular mutant protein 13(gene name synonym) psi-mi:kre9_yeast(display_long)|uniprotkb:KRE9(gene name)|psi-mi:KRE9(display_short)|uniprotkb:J0504(orf name)|uniprotkb:YJL174W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327286|imex:IM-14275-1215 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000139|refseq:NP_009510.1|mint:P38195|dip:DIP-1214N|ensemblfungi:YBL043W(gene)|ensemblfungi:YBL043W_mRNA(transcript)|go:"GO:0071555"(cell wall organization)|interpro:IPR037738 refseq:NP_012361.1|sgd:S000003710|ensemblfungi:YJL174W(gene)|ensemblfungi:YJL174W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0006077"("(1->6)-beta-D-glucan metabolic process")|go:"GO:0006078"("(1->6)-beta-D-glucan biosynthetic process")|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0042546"(cell wall biogenesis)|interpro:IPR008659(Yeast cell wall synthesis KRE9KNH1)|interpro:IPR018466|dip:DIP-5609N|mint:P39005 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wChxahNuAMsxIWlnYj9CzbY2EMM559292 rogid:jBKI+ZR5HsosCLJPinn8LNFqIcU559292 intact-crc:45B2D9657656EFF2|rigid:4kw8K+QkP4FAYgO+CFRtaRCRx/w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38196 uniprotkb:P38234 intact:EBI-7158|uniprotkb:D6VPV6|ensemblfungi:YBL042C intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C psi-mi:fui1_yeast(display_long)|uniprotkb:FUI1(gene name)|psi-mi:FUI1(display_short)|uniprotkb:YBL0406(orf name)|uniprotkb:YBL042C(locus name) psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327297|imex:IM-14275-1216 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009511.1|sgd:S000000138|dip:DIP-1321N|mint:P38196|ensemblfungi:YBL042C(gene)|ensemblfungi:YBL042C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015205"(nucleobase transmembrane transporter activity)|go:"GO:0015213"(uridine transmembrane transporter activity)|go:"GO:0015851"(nucleobase transport)|go:"GO:0015862"(uridine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR001248(Permease for cytosine/purines, uracil, thiamine, allantoin)|interpro:IPR012681(Nucleobase cation symporter-1, NCS1) refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ESbe5XfGhfMFQk2sgjqm+duIHyg559292 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 intact-crc:2BF5936E50B1684F|rigid:LN8Lc/riVeOaYZ7g0HyFtAQVnw4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38196 uniprotkb:P50276 intact:EBI-7158|uniprotkb:D6VPV6|ensemblfungi:YBL042C intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:fui1_yeast(display_long)|uniprotkb:FUI1(gene name)|psi-mi:FUI1(display_short)|uniprotkb:YBL0406(orf name)|uniprotkb:YBL042C(locus name) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327308|imex:IM-14275-1217 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009511.1|sgd:S000000138|dip:DIP-1321N|mint:P38196|ensemblfungi:YBL042C(gene)|ensemblfungi:YBL042C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015205"(nucleobase transmembrane transporter activity)|go:"GO:0015213"(uridine transmembrane transporter activity)|go:"GO:0015851"(nucleobase transport)|go:"GO:0015862"(uridine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR001248(Permease for cytosine/purines, uracil, thiamine, allantoin)|interpro:IPR012681(Nucleobase cation symporter-1, NCS1) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ESbe5XfGhfMFQk2sgjqm+duIHyg559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:986268148A010E64|rigid:2HGjV19K+Gkl+avmVOgmReV7Cjw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53278 uniprotkb:P38196 intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C intact:EBI-7158|uniprotkb:D6VPV6|ensemblfungi:YBL042C psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name) psi-mi:fui1_yeast(display_long)|uniprotkb:FUI1(gene name)|psi-mi:FUI1(display_short)|uniprotkb:YBL0406(orf name)|uniprotkb:YBL042C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327319|imex:IM-14275-1218 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome) refseq:NP_009511.1|sgd:S000000138|dip:DIP-1321N|mint:P38196|ensemblfungi:YBL042C(gene)|ensemblfungi:YBL042C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015205"(nucleobase transmembrane transporter activity)|go:"GO:0015213"(uridine transmembrane transporter activity)|go:"GO:0015851"(nucleobase transport)|go:"GO:0015862"(uridine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR001248(Permease for cytosine/purines, uracil, thiamine, allantoin)|interpro:IPR012681(Nucleobase cation symporter-1, NCS1) psi-mi:"MI:0469"(intact) crc64:D482327C9274C026 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292 rogid:ESbe5XfGhfMFQk2sgjqm+duIHyg559292 intact-crc:44FDF811B2875357|rigid:cyDyZPuyWGVf7x0wHReednauIDM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02785 uniprotkb:P38196 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C intact:EBI-7158|uniprotkb:D6VPV6|ensemblfungi:YBL042C psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:fui1_yeast(display_long)|uniprotkb:FUI1(gene name)|psi-mi:FUI1(display_short)|uniprotkb:YBL0406(orf name)|uniprotkb:YBL042C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327330|imex:IM-14275-1219 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) refseq:NP_009511.1|sgd:S000000138|dip:DIP-1321N|mint:P38196|ensemblfungi:YBL042C(gene)|ensemblfungi:YBL042C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015205"(nucleobase transmembrane transporter activity)|go:"GO:0015213"(uridine transmembrane transporter activity)|go:"GO:0015851"(nucleobase transport)|go:"GO:0015862"(uridine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR001248(Permease for cytosine/purines, uracil, thiamine, allantoin)|interpro:IPR012681(Nucleobase cation symporter-1, NCS1) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 rogid:ESbe5XfGhfMFQk2sgjqm+duIHyg559292 intact-crc:FC60BC5F0261E32B|rigid:CN+fzOFzIeerK8rJIRGeiaNnuAk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38198 uniprotkb:P33895 intact:EBI-18463|uniprotkb:D6VPW5|ensemblfungi:YBL034C intact:EBI-12377|uniprotkb:Q6B1X5|ensemblfungi:YOL069W|uniprotkb:D6W1Z8 psi-mi:stu1_yeast(display_long)|uniprotkb:STU1(gene name)|psi-mi:STU1(display_short)|uniprotkb:YBL034C(locus name)|uniprotkb:YBL0416(orf name)|uniprotkb:Suppressor of tubulin 1(gene name synonym) psi-mi:nuf2_yeast(display_long)|uniprotkb:YOL069W(locus name)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327341|imex:IM-14275-1220 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009519.1|sgd:S000000130|ensemblfungi:YBL034C(gene)|ensemblfungi:YBL034C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005827"(polar microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0043515"(kinetochore binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0060172"(astral microtubule depolymerization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024395|rcsb pdb:6COK|dip:DIP-2633N|mint:P38198 ensemblfungi:YOL069W(gene)|ensemblfungi:YOL069W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005816"(spindle pole body)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|rcsb pdb:5TCS|rcsb pdb:5TD8|go:"GO:0045132"(meiotic chromosome segregation)|refseq:NP_014572.1|sgd:S000005430|mint:P33895|dip:DIP-1481N psi-mi:"MI:0469"(intact) crc64:E7F64B5A5D03588D - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:X80UuWOiEwr+RkKUjP2nADpuWK8559292 rogid:oof/8nhKWQCx5bp4lvc7f33OO+0559292 intact-crc:73CE16BD510A2538|rigid:6IiUOMMiuJsGosrZa+uejBB3zVI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38203 uniprotkb:P06102 intact:EBI-180|ensemblfungi:YBL026W|uniprotkb:D6VPX4 intact:EBI-12165|uniprotkb:D6VVP4|uniprotkb:Q6B233|ensemblfungi:YIL038C psi-mi:lsm2_yeast(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:Small nuclear ribonucleoprotein D homolog SNP3(gene name synonym)|uniprotkb:SMX5(gene name synonym)|uniprotkb:SNP3(gene name synonym)|uniprotkb:YBL0425(orf name)|uniprotkb:YBL026W(locus name) psi-mi:not3_yeast(display_long)|uniprotkb:NOT3(gene name)|psi-mi:NOT3(display_short)|uniprotkb:YIL038C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327352|imex:IM-14275-1221 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009527.1|sgd:S000000122|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|ensemblfungi:YBL026W(gene)|ensemblfungi:YBL026W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|mint:P38203|dip:DIP-794N|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:4N0A|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR038635|interpro:IPR040168|ensemblfungi:YIL038C(gene)|ensemblfungi:YIL038C_mRNA(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|refseq:NP_012226.3|sgd:S000001300|dip:DIP-2256N|mint:P06102 psi-mi:"MI:0469"(intact) crc64:C23856268CEE92E2 crc64:69B76694FCC6846F figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3E5c7Mzg433awFPmamamsKjtJmY559292 rogid:EfakZPDNU3FZeI5+rnu7YV1UsCg559292 intact-crc:E4A43A04AACF31B6|rigid:duTLR+qcIarYe1IIQc5EWJ1tzJ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38203 uniprotkb:P25655 intact:EBI-180|ensemblfungi:YBL026W|uniprotkb:D6VPX4 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W psi-mi:lsm2_yeast(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:Small nuclear ribonucleoprotein D homolog SNP3(gene name synonym)|uniprotkb:SMX5(gene name synonym)|uniprotkb:SNP3(gene name synonym)|uniprotkb:YBL0425(orf name)|uniprotkb:YBL026W(locus name) psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327363|imex:IM-14275-1222 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009527.1|sgd:S000000122|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|ensemblfungi:YBL026W(gene)|ensemblfungi:YBL026W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|mint:P38203|dip:DIP-794N|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:4N0A|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 psi-mi:"MI:0469"(intact) crc64:C23856268CEE92E2 crc64:5B2AE15BCF95E009 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3E5c7Mzg433awFPmamamsKjtJmY559292 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 intact-crc:A0B463B64CF45823|rigid:7yihtiiCIIMhQY1XUGFAz+fp5i0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32588 uniprotkb:P38203 intact:EBI-14231|ensemblfungi:YNL016W|uniprotkb:D6W1G2 intact:EBI-180|ensemblfungi:YBL026W|uniprotkb:D6VPX4 psi-mi:pub1_yeast(display_long)|uniprotkb:ARS consensus-binding protein ACBP-60(gene name synonym)|uniprotkb:Poly uridylate-binding protein(gene name synonym)|uniprotkb:PUB1(gene name)|psi-mi:PUB1(display_short)|uniprotkb:RNP1(gene name synonym)|uniprotkb:YNL016W(locus name)|uniprotkb:N2842(orf name) psi-mi:lsm2_yeast(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:Small nuclear ribonucleoprotein D homolog SNP3(gene name synonym)|uniprotkb:SMX5(gene name synonym)|uniprotkb:SNP3(gene name synonym)|uniprotkb:YBL0425(orf name)|uniprotkb:YBL026W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327374|imex:IM-14275-1223 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014382.1|sgd:S000004961|ensemblfungi:YNL016W(gene)|ensemblfungi:YNL016W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043488"(regulation of mRNA stability)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034509|interpro:IPR034639|interpro:IPR035979|rcsb pdb:2LA4|rcsb pdb:3MD1|rcsb pdb:3MD3|rcsb pdb:6Z29|mint:P32588|dip:DIP-5480N refseq:NP_009527.1|sgd:S000000122|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|ensemblfungi:YBL026W(gene)|ensemblfungi:YBL026W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|mint:P38203|dip:DIP-794N|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:4N0A|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:3B81A7735505D3CA crc64:C23856268CEE92E2 figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8xFMuEva7leVYDKg3WOmvPtRTFk559292 rogid:3E5c7Mzg433awFPmamamsKjtJmY559292 intact-crc:992B753DB529E8FE|rigid:K1avmHuXmK5wegbNVcXX2eO/JxM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38203 uniprotkb:P40070 intact:EBI-180|ensemblfungi:YBL026W|uniprotkb:D6VPX4 intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W psi-mi:lsm2_yeast(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:Small nuclear ribonucleoprotein D homolog SNP3(gene name synonym)|uniprotkb:SMX5(gene name synonym)|uniprotkb:SNP3(gene name synonym)|uniprotkb:YBL0425(orf name)|uniprotkb:YBL026W(locus name) psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327385|imex:IM-14275-1224 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009527.1|sgd:S000000122|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|ensemblfungi:YBL026W(gene)|ensemblfungi:YBL026W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|mint:P38203|dip:DIP-794N|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:4N0A|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:C23856268CEE92E2 crc64:69CAC1F01D5BFA98 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3E5c7Mzg433awFPmamamsKjtJmY559292 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 intact-crc:E4E1F325760900CA|rigid:O2gAN7rNDZeFdBgfqHOVe2ZS1Io false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P57743 uniprotkb:P38203 intact:EBI-10227|uniprotkb:Q05176|uniprotkb:Q06759|uniprotkb:D6VZ73|ensemblfungi:YLR438C-A intact:EBI-180|ensemblfungi:YBL026W|uniprotkb:D6VPX4 psi-mi:lsm3_yeast(display_long)|uniprotkb:LSM3(gene name)|psi-mi:LSM3(display_short)|uniprotkb:SMX4(gene name synonym)|uniprotkb:USS2(gene name synonym)|uniprotkb:YLR438C-A(locus name)|uniprotkb:SmX4 protein(gene name synonym) psi-mi:lsm2_yeast(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:Small nuclear ribonucleoprotein D homolog SNP3(gene name synonym)|uniprotkb:SMX5(gene name synonym)|uniprotkb:SNP3(gene name synonym)|uniprotkb:YBL0425(orf name)|uniprotkb:YBL026W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327396|imex:IM-14275-1225 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006434|ensemblfungi:YLR438C-A(gene)|ensemblfungi:YLR438C-A_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034105|interpro:IPR040002|rcsb pdb:3BW1|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:4N0A|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039|rcsb pdb:4M75|refseq:NP_013543.3|dip:DIP-2587N|mint:P57743 refseq:NP_009527.1|sgd:S000000122|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|ensemblfungi:YBL026W(gene)|ensemblfungi:YBL026W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|mint:P38203|dip:DIP-794N|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:4N0A|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:787084EF6A5945B7 crc64:C23856268CEE92E2 figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nYl7At1SnlSwN+nWr1F1xm0tdDE559292 rogid:3E5c7Mzg433awFPmamamsKjtJmY559292 intact-crc:24ACD47232B1FEC7|rigid:yPb556fK6kL+CCz5cPz1fbyHYvc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38206 uniprotkb:P15496 intact:EBI-15028|uniprotkb:Q05814|uniprotkb:D6VPY0|ensemblfungi:YBL020W intact:EBI-8902|ensemblfungi:YPL117C|uniprotkb:D6W3Q1 psi-mi:rft1_yeast(display_long)|uniprotkb:RFT1(gene name)|psi-mi:RFT1(display_short)|uniprotkb:YBL020W(locus name)|uniprotkb:YBL0442(orf name)|uniprotkb:Requiring fifty-three protein 1(gene name synonym) psi-mi:idi1_yeast(display_long)|uniprotkb:Isopentenyl pyrophosphate isomerase(gene name synonym)|uniprotkb:IDI1(gene name)|psi-mi:IDI1(display_short)|uniprotkb:BOT2(gene name synonym)|uniprotkb:YPL117C(locus name)|uniprotkb:LPH10C(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327407|imex:IM-14275-1226 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009533.1|sgd:S000000116|ensemblfungi:YBL020W(gene)|ensemblfungi:YBL020W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034202"(glycolipid floppase activity)|go:"GO:0034203"(glycolipid translocation)|interpro:IPR007594(RFT1)|dip:DIP-3885N|mint:P38206 ensemblfungi:YPL117C(gene)|ensemblfungi:YPL117C_mRNA(transcript)|go:"GO:0004452"(isopentenyl-diphosphate delta-isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009240"(isopentenyl diphosphate biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0045337"(farnesyl diphosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050992"(dimethylallyl diphosphate biosynthetic process)|reactome:R-SCE-191273|refseq:NP_015208.1|sgd:S000006038|interpro:IPR011876(Isopentenyl-diphosphate delta-isomerase, type 1)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|mint:P15496 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nBfsGoVh81NwPryblR48jOVVQsU559292 rogid:KQ9qSb2grQ4DQip7atYPeCwp5QM559292 intact-crc:197D87E4AD4C87BF|rigid:Mdv8DqCHx8+Bn18gtZiN86PURyE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38206 uniprotkb:Q07500 intact:EBI-15028|uniprotkb:Q05814|uniprotkb:D6VPY0|ensemblfungi:YBL020W intact:EBI-38178|uniprotkb:D6VRR4|ensemblfungi:YDL085W psi-mi:rft1_yeast(display_long)|uniprotkb:RFT1(gene name)|psi-mi:RFT1(display_short)|uniprotkb:YBL020W(locus name)|uniprotkb:YBL0442(orf name)|uniprotkb:Requiring fifty-three protein 1(gene name synonym) psi-mi:ndh2_yeast(display_long)|uniprotkb:NDE2(gene name)|psi-mi:NDE2(display_short)|uniprotkb:NDH2(gene name synonym)|uniprotkb:YDL085W(locus name)|uniprotkb:External NADH dehydrogenase 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327418|imex:IM-14275-1227 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009533.1|sgd:S000000116|ensemblfungi:YBL020W(gene)|ensemblfungi:YBL020W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034202"(glycolipid floppase activity)|go:"GO:0034203"(glycolipid translocation)|interpro:IPR007594(RFT1)|dip:DIP-3885N|mint:P38206 refseq:NP_010198.1|sgd:S000002243|mint:Q07500|dip:DIP-5023N|ensemblfungi:YDL085W(gene)|ensemblfungi:YDL085W_mRNA(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006116"(NADH oxidation)|go:"GO:0019655"(glycolytic fermentation to ethanol)|go:"GO:0050136"("NADH dehydrogenase (quinone) activity")|interpro:IPR023753|interpro:IPR036188 psi-mi:"MI:0469"(intact) - crc64:291E81D0FC6D3FD7 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nBfsGoVh81NwPryblR48jOVVQsU559292 rogid:VDKbGYjFURtBVpghiIp4aKVVAfI559292 intact-crc:7F79E93BEB5BE154|rigid:IiaDI6Qgcw9+PYjiy29KfqcI2Ks false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38211 uniprotkb:P40540 intact:EBI-21377|uniprotkb:P89496|uniprotkb:D6VQ05|ensemblfungi:YBR004C intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C psi-mi:gpi18_yeast(display_long)|uniprotkb:GPI mannosyltransferase II(gene name synonym)|uniprotkb:YBR0110(orf name)|uniprotkb:YBR004C(locus name)|uniprotkb:GPI18(gene name)|psi-mi:GPI18(display_short)|uniprotkb:Glycosylphosphatidylinositol-anchor biosynthesis protein 18(gene name synonym) psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327429|imex:IM-14275-1228 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009558.2|sgd:S000000208|mint:P38211|dip:DIP-3954N|ensemblfungi:YBR004C(gene)|ensemblfungi:YBR004C_mRNA(transcript)|go:"GO:0000009"(alpha-1,6-mannosyltransferase activity)|go:"GO:0000030"(mannosyltransferase activity)|go:"GO:0004376"(glycolipid mannosyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031501"(mannosyltransferase complex)|interpro:IPR007315(Mannosyltransferase, PIG-V)|reactome:R-SCE-162710|go:"GO:0006506"(GPI anchor biosynthetic process) refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) crc64:9C81918DF1A37B44 crc64:6DBEEEE7722203B0 figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GiIeSrv97fvc77qA/T+5i4OQNFI559292 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 intact-crc:287008DC4597E711|rigid:cwZnudW2s1SlEYh8JvHU3R7zIns false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38216 uniprotkb:P53131 intact:EBI-21401|uniprotkb:D6VQ18|ensemblfungi:YBR016W intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 psi-mi:ybm6_yeast(display_long)|uniprotkb:YBR0222(orf name)|uniprotkb:YBR016W(locus name) psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327440|imex:IM-14275-1229 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000220|refseq:NP_009572.1|mint:P38216|ensemblfungi:YBR016W(gene)|ensemblfungi:YBR016W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0070250"(mating projection membrane) go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131 psi-mi:"MI:0469"(intact) - crc64:DA8A085EC50FF430 figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cWxsk1wtMug5sevyIfJy41hhZx4559292 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 intact-crc:3A380DE1197A4B89|rigid:53KtHwZQVMd40n281ZU498d9o34 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38225 uniprotkb:P14359 intact:EBI-6819|uniprotkb:O60021|uniprotkb:Q86ZS3|uniprotkb:D6VQ41|ensemblfungi:YBR041W intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:fat1_yeast(display_long)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:Very-long-chain acyl-CoA synthetase(gene name synonym)|uniprotkb:YBR0411(orf name)|uniprotkb:YBR041W(locus name) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327451|imex:IM-14275-1230 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009597.2|sgd:S000000245|mint:P38225|dip:DIP-5048N|ensemblfungi:YBR041W(gene)|ensemblfungi:YBR041W_mRNA(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0071944"(cell periphery)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR030310|interpro:IPR042099|reactome:R-SCE-159418|reactome:R-SCE-193368|reactome:R-SCE-193775|reactome:R-SCE-389599|reactome:R-SCE-6798695|reactome:R-SCE-804914|reactome:R-SCE-9033241 refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) crc64:509A5DEDDEE98823 crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mGjvEcQ/ZVHp/P+89KaQ7DrjcQg559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:07F7221361BA9A52|rigid:ytOe2SOwvqGFrQU43ZZx92a7YCs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38225 uniprotkb:P28321 intact:EBI-6819|uniprotkb:O60021|uniprotkb:Q86ZS3|uniprotkb:D6VQ41|ensemblfungi:YBR041W intact:EBI-26790|uniprotkb:D6VXJ4|ensemblfungi:YKL094W psi-mi:fat1_yeast(display_long)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:Very-long-chain acyl-CoA synthetase(gene name synonym)|uniprotkb:YBR0411(orf name)|uniprotkb:YBR041W(locus name) psi-mi:mgll_yeast(display_long)|uniprotkb:YJU3(gene name)|psi-mi:YJU3(display_short)|uniprotkb:Monoacylglycerol hydrolase(gene name synonym)|uniprotkb:Monoacylglycerol lipase(gene name synonym)|uniprotkb:Serine hydrolase YJU3(gene name synonym)|uniprotkb:YKL441(orf name)|uniprotkb:YKL094W(locus name)|uniprotkb:Fatty acid ethyl ester hydrolase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327462|imex:IM-14275-1231 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009597.2|sgd:S000000245|mint:P38225|dip:DIP-5048N|ensemblfungi:YBR041W(gene)|ensemblfungi:YBR041W_mRNA(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0071944"(cell periphery)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR030310|interpro:IPR042099|reactome:R-SCE-159418|reactome:R-SCE-193368|reactome:R-SCE-193775|reactome:R-SCE-389599|reactome:R-SCE-6798695|reactome:R-SCE-804914|reactome:R-SCE-9033241 interpro:IPR022742|refseq:NP_012829.1|sgd:S000001577|mint:P28321|interpro:IPR029058|ensemblfungi:YKL094W(gene)|ensemblfungi:YKL094W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0071944"(cell periphery)|rcsb pdb:4ZWN|rcsb pdb:4ZXF psi-mi:"MI:0469"(intact) crc64:509A5DEDDEE98823 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mGjvEcQ/ZVHp/P+89KaQ7DrjcQg559292 rogid:IHpY1aez3MG+bn7bThCBdvE6KMw559292 intact-crc:3B1AE78B36440398|rigid:6UcEU7AWmMroK1BweIQjDcxAOCc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34163 uniprotkb:P38225 intact:EBI-19177|uniprotkb:D6VX56|ensemblfungi:YKL140W intact:EBI-6819|uniprotkb:O60021|uniprotkb:Q86ZS3|uniprotkb:D6VQ41|ensemblfungi:YBR041W psi-mi:tgl1_yeast(display_long)|uniprotkb:TGL1(gene name)|psi-mi:TGL1(display_short)|uniprotkb:YKL140W(locus name)|uniprotkb:YKL5(orf name)|uniprotkb:Triglyceride lipase-cholesterol esterase 1(gene name synonym) psi-mi:fat1_yeast(display_long)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:Very-long-chain acyl-CoA synthetase(gene name synonym)|uniprotkb:YBR0411(orf name)|uniprotkb:YBR041W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327473|imex:IM-14275-1232 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012782.1|sgd:S000001623|ensemblfungi:YKL140W(gene)|ensemblfungi:YKL140W_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR029058|dip:DIP-6306N|mint:P34163 refseq:NP_009597.2|sgd:S000000245|mint:P38225|dip:DIP-5048N|ensemblfungi:YBR041W(gene)|ensemblfungi:YBR041W_mRNA(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0071944"(cell periphery)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR030310|interpro:IPR042099|reactome:R-SCE-159418|reactome:R-SCE-193368|reactome:R-SCE-193775|reactome:R-SCE-389599|reactome:R-SCE-6798695|reactome:R-SCE-804914|reactome:R-SCE-9033241 psi-mi:"MI:0469"(intact) crc64:32D1F230701CB083 crc64:509A5DEDDEE98823 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:/f3560MDciadPqvZ0iY9e9oVBH8559292 rogid:mGjvEcQ/ZVHp/P+89KaQ7DrjcQg559292 intact-crc:DEF11DE13F4B9894|rigid:Ce8k0pQ1ir65y16X8YUGif0PKHI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38225 uniprotkb:P35196 intact:EBI-6819|uniprotkb:O60021|uniprotkb:Q86ZS3|uniprotkb:D6VQ41|ensemblfungi:YBR041W intact:EBI-14943|uniprotkb:D6VQ03|ensemblfungi:YBR002C psi-mi:fat1_yeast(display_long)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:Very-long-chain acyl-CoA synthetase(gene name synonym)|uniprotkb:YBR0411(orf name)|uniprotkb:YBR041W(locus name) psi-mi:rer2_yeast(display_long)|uniprotkb:"Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific)"(gene name synonym)|uniprotkb:YBR0107(orf name)|uniprotkb:RER2(gene name)|psi-mi:RER2(display_short)|uniprotkb:YBR002C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327484|imex:IM-14275-1233 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009597.2|sgd:S000000245|mint:P38225|dip:DIP-5048N|ensemblfungi:YBR041W(gene)|ensemblfungi:YBR041W_mRNA(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0071944"(cell periphery)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR030310|interpro:IPR042099|reactome:R-SCE-159418|reactome:R-SCE-193368|reactome:R-SCE-193775|reactome:R-SCE-389599|reactome:R-SCE-6798695|reactome:R-SCE-804914|reactome:R-SCE-9033241 interpro:IPR036424|refseq:NP_009556.1|sgd:S000000206|interpro:IPR001441(Di-trans-poly-cis-decaprenylcistransferase)|interpro:IPR018520|ensemblfungi:YBR002C(gene)|ensemblfungi:YBR002C_mRNA(transcript)|go:"GO:0002094"(polyprenyltransferase activity)|go:"GO:0004659"(prenyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016094"(polyprenol biosynthetic process)|go:"GO:0019408"(dolichol biosynthetic process)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0045547"(dehydrodolichyl diphosphate synthase activity)|go:"GO:1904423"(dehydrodolichyl diphosphate synthase complex)|reactome:R-SCE-446199|mint:P35196 psi-mi:"MI:0469"(intact) crc64:509A5DEDDEE98823 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mGjvEcQ/ZVHp/P+89KaQ7DrjcQg559292 rogid:gVl9E/6GKqKsUp/5VLdT5XGbjUM559292 intact-crc:3120F2964D0DC568|rigid:HNYRsgCsqYCX92Mc9yXsSfmdahk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35844 uniprotkb:P38225 intact:EBI-9648|ensemblfungi:YPL145C|uniprotkb:D6W3M4|uniprotkb:E9P8U8 intact:EBI-6819|uniprotkb:O60021|uniprotkb:Q86ZS3|uniprotkb:D6VQ41|ensemblfungi:YBR041W psi-mi:kes1_yeast(display_long)|uniprotkb:KES1(gene name)|psi-mi:KES1(display_short)|uniprotkb:OSH4(gene name synonym)|uniprotkb:Protein KES1(gene name synonym)|uniprotkb:LPI3C(orf name)|uniprotkb:P2614(orf name)|uniprotkb:YPL145C(locus name) psi-mi:fat1_yeast(display_long)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:Very-long-chain acyl-CoA synthetase(gene name synonym)|uniprotkb:YBR0411(orf name)|uniprotkb:YBR041W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327495|imex:IM-14275-1234 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL145C(gene)|ensemblfungi:YPL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035621"(ER to Golgi ceramide transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|rcsb pdb:1ZHT|rcsb pdb:1ZHW|rcsb pdb:1ZHX|rcsb pdb:1ZHY|rcsb pdb:1ZHZ|rcsb pdb:1ZI7|rcsb pdb:3SPW|rcsb pdb:4F4B|rcsb pdb:4FES|rcsb pdb:4JCH|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_015180.1|sgd:S000006066|dip:DIP-2867N|mint:P35844 refseq:NP_009597.2|sgd:S000000245|mint:P38225|dip:DIP-5048N|ensemblfungi:YBR041W(gene)|ensemblfungi:YBR041W_mRNA(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0071944"(cell periphery)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR030310|interpro:IPR042099|reactome:R-SCE-159418|reactome:R-SCE-193368|reactome:R-SCE-193775|reactome:R-SCE-389599|reactome:R-SCE-6798695|reactome:R-SCE-804914|reactome:R-SCE-9033241 psi-mi:"MI:0469"(intact) - crc64:509A5DEDDEE98823 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6vsHrA4RScGr2+xmii0wiuvK1OM559292 rogid:mGjvEcQ/ZVHp/P+89KaQ7DrjcQg559292 intact-crc:33599B9F047CF062|rigid:zRp+QSku72FKlNt23uxgRr/lYJg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38225 uniprotkb:P38225 intact:EBI-6819|uniprotkb:O60021|uniprotkb:Q86ZS3|uniprotkb:D6VQ41|ensemblfungi:YBR041W intact:EBI-6819|uniprotkb:O60021|uniprotkb:Q86ZS3|uniprotkb:D6VQ41|ensemblfungi:YBR041W psi-mi:fat1_yeast(display_long)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:Very-long-chain acyl-CoA synthetase(gene name synonym)|uniprotkb:YBR0411(orf name)|uniprotkb:YBR041W(locus name) psi-mi:fat1_yeast(display_long)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:Very-long-chain acyl-CoA synthetase(gene name synonym)|uniprotkb:YBR0411(orf name)|uniprotkb:YBR041W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327506|imex:IM-14275-1235 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009597.2|sgd:S000000245|mint:P38225|dip:DIP-5048N|ensemblfungi:YBR041W(gene)|ensemblfungi:YBR041W_mRNA(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0071944"(cell periphery)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR030310|interpro:IPR042099|reactome:R-SCE-159418|reactome:R-SCE-193368|reactome:R-SCE-193775|reactome:R-SCE-389599|reactome:R-SCE-6798695|reactome:R-SCE-804914|reactome:R-SCE-9033241 refseq:NP_009597.2|sgd:S000000245|mint:P38225|dip:DIP-5048N|ensemblfungi:YBR041W(gene)|ensemblfungi:YBR041W_mRNA(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0071944"(cell periphery)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR030310|interpro:IPR042099|reactome:R-SCE-159418|reactome:R-SCE-193368|reactome:R-SCE-193775|reactome:R-SCE-389599|reactome:R-SCE-6798695|reactome:R-SCE-804914|reactome:R-SCE-9033241 psi-mi:"MI:0469"(intact) crc64:509A5DEDDEE98823 crc64:509A5DEDDEE98823 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mGjvEcQ/ZVHp/P+89KaQ7DrjcQg559292 rogid:mGjvEcQ/ZVHp/P+89KaQ7DrjcQg559292 intact-crc:8F89824EBCCBEB63|rigid:gXIuONmh3eyYzSUEYZhWE7IfVQ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38604 uniprotkb:P38225 intact:EBI-6572|uniprotkb:Q92327|uniprotkb:D3DL21|ensemblfungi:YHR072W intact:EBI-6819|uniprotkb:O60021|uniprotkb:Q86ZS3|uniprotkb:D6VQ41|ensemblfungi:YBR041W psi-mi:erg7_yeast(display_long)|uniprotkb:Oxidosqualene--lanosterol cyclase(gene name synonym)|uniprotkb:2,3-epoxysqualene--lanosterol cyclase(gene name synonym)|uniprotkb:YHR072W(locus name)|uniprotkb:ERG7(gene name)|psi-mi:ERG7(display_short) psi-mi:fat1_yeast(display_long)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:Very-long-chain acyl-CoA synthetase(gene name synonym)|uniprotkb:YBR0411(orf name)|uniprotkb:YBR041W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327517|imex:IM-14275-1236 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011939.2|sgd:S000001114|mint:P38604|dip:DIP-8319N|ensemblfungi:YHR072W(gene)|ensemblfungi:YHR072W_mRNA(transcript)|go:"GO:0000250"(lanosterol synthase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016104"(triterpenoid biosynthetic process)|go:"GO:0042300"(beta-amyrin synthase activity)|interpro:IPR002365(Terpene synthase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR018333|interpro:IPR032696|interpro:IPR032697|reactome:R-SCE-191273 refseq:NP_009597.2|sgd:S000000245|mint:P38225|dip:DIP-5048N|ensemblfungi:YBR041W(gene)|ensemblfungi:YBR041W_mRNA(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0071944"(cell periphery)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR030310|interpro:IPR042099|reactome:R-SCE-159418|reactome:R-SCE-193368|reactome:R-SCE-193775|reactome:R-SCE-389599|reactome:R-SCE-6798695|reactome:R-SCE-804914|reactome:R-SCE-9033241 psi-mi:"MI:0469"(intact) - crc64:509A5DEDDEE98823 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zqDPA3GvKWkMTmH97TcdF8HOHBU559292 rogid:mGjvEcQ/ZVHp/P+89KaQ7DrjcQg559292 intact-crc:BFCA859AF9ECCA5A|rigid:dnEAozRQkv0WBE/Bt6tFqp/hO/4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38225 uniprotkb:P40471 intact:EBI-6819|uniprotkb:O60021|uniprotkb:Q86ZS3|uniprotkb:D6VQ41|ensemblfungi:YBR041W intact:EBI-25213|uniprotkb:D6VVG3|ensemblfungi:YIL124W psi-mi:fat1_yeast(display_long)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:Very-long-chain acyl-CoA synthetase(gene name synonym)|uniprotkb:YBR0411(orf name)|uniprotkb:YBR041W(locus name) psi-mi:ayr1_yeast(display_long)|uniprotkb:AYR1(gene name)|psi-mi:AYR1(display_short)|uniprotkb:Acylglycerone-phosphate reductase(gene name synonym)|uniprotkb:1-acyl DHAP reductase(gene name synonym)|uniprotkb:Acyl/alkyl DHAP reductase(gene name synonym)|uniprotkb:GBG1(gene name synonym)|uniprotkb:Triacylglycerol lipase AYR1(gene name synonym)|uniprotkb:YIL124W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327528|imex:IM-14275-1237 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009597.2|sgd:S000000245|mint:P38225|dip:DIP-5048N|ensemblfungi:YBR041W(gene)|ensemblfungi:YBR041W_mRNA(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0071944"(cell periphery)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR030310|interpro:IPR042099|reactome:R-SCE-159418|reactome:R-SCE-193368|reactome:R-SCE-193775|reactome:R-SCE-389599|reactome:R-SCE-6798695|reactome:R-SCE-804914|reactome:R-SCE-9033241 sgd:S000001386|refseq:NP_012142.3|mint:P40471|dip:DIP-4614N|ensemblfungi:YIL124W(gene)|ensemblfungi:YIL124W_mRNA(transcript)|go:"GO:0000140"(acylglycerone-phosphate reductase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0102566"(1-acyl dihydroxyacetone phosphate reductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291 psi-mi:"MI:0469"(intact) crc64:509A5DEDDEE98823 crc64:B614C0E0B1FB0CE0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mGjvEcQ/ZVHp/P+89KaQ7DrjcQg559292 rogid:WE4RmSXARj683MNUEsYGLis36Xo559292 intact-crc:EEDF842CF90A6BF3|rigid:4Bk0PWZ8Gh8V92aDSFJRIAtffcQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38225 uniprotkb:Q07804 intact:EBI-6819|uniprotkb:O60021|uniprotkb:Q86ZS3|uniprotkb:D6VQ41|ensemblfungi:YBR041W intact:EBI-36254|uniprotkb:D6VXZ0|ensemblfungi:YLL012W psi-mi:fat1_yeast(display_long)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:Very-long-chain acyl-CoA synthetase(gene name synonym)|uniprotkb:YBR0411(orf name)|uniprotkb:YBR041W(locus name) psi-mi:yeh1_yeast(display_long)|uniprotkb:Steryl ester hydrolase 1(gene name synonym)|uniprotkb:YEH1(gene name)|psi-mi:YEH1(display_short)|uniprotkb:YLL012W(locus name)|uniprotkb:L1329(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327539|imex:IM-14275-1238 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009597.2|sgd:S000000245|mint:P38225|dip:DIP-5048N|ensemblfungi:YBR041W(gene)|ensemblfungi:YBR041W_mRNA(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0071944"(cell periphery)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR030310|interpro:IPR042099|reactome:R-SCE-159418|reactome:R-SCE-193368|reactome:R-SCE-193775|reactome:R-SCE-389599|reactome:R-SCE-6798695|reactome:R-SCE-804914|reactome:R-SCE-9033241 refseq:NP_013089.1|sgd:S000003935|mint:Q07804|dip:DIP-4156N|ensemblfungi:YLL012W(gene)|ensemblfungi:YLL012W_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016125"(sterol metabolic process)|interpro:IPR006693(AB-hydrolase associated lipase region)|interpro:IPR029058|reactome:R-SCE-192456|reactome:R-SCE-6809371 psi-mi:"MI:0469"(intact) crc64:509A5DEDDEE98823 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mGjvEcQ/ZVHp/P+89KaQ7DrjcQg559292 rogid:Fv+RBBi6c7i++sW0AISZDXDrlrI559292 intact-crc:A4C0ABEBCCF55E76|rigid:jPqP0zdK7o14FCMH8tp1COuA3mg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38225 uniprotkb:Q12168 intact:EBI-6819|uniprotkb:O60021|uniprotkb:Q86ZS3|uniprotkb:D6VQ41|ensemblfungi:YBR041W intact:EBI-32973|uniprotkb:Q07268|uniprotkb:D6VYD8|ensemblfungi:YLR144C psi-mi:fat1_yeast(display_long)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:Very-long-chain acyl-CoA synthetase(gene name synonym)|uniprotkb:YBR0411(orf name)|uniprotkb:YBR041W(locus name) psi-mi:eng2_yeast(display_long)|uniprotkb:ACF2(gene name)|psi-mi:ACF2(display_short)|uniprotkb:YLR144C(locus name)|uniprotkb:Laminarinase-2(gene name synonym)|uniprotkb:ENG2(gene name synonym)|uniprotkb:PCA1(gene name synonym)|uniprotkb:L3180(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327550|imex:IM-14275-1239 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009597.2|sgd:S000000245|mint:P38225|dip:DIP-5048N|ensemblfungi:YBR041W(gene)|ensemblfungi:YBR041W_mRNA(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0071944"(cell periphery)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR030310|interpro:IPR042099|reactome:R-SCE-159418|reactome:R-SCE-193368|reactome:R-SCE-193775|reactome:R-SCE-389599|reactome:R-SCE-6798695|reactome:R-SCE-804914|reactome:R-SCE-9033241 refseq:NP_013245.1|sgd:S000004134|mint:Q12168|dip:DIP-2889N|ensemblfungi:YLR144C(gene)|ensemblfungi:YLR144C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042973"(glucan endo-1,3-beta-D-glucosidase activity)|go:"GO:0052861"(glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group)|go:"GO:0052862"(glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group)|interpro:IPR005200(Glycoside hydrolase, family 81)|interpro:IPR040451|interpro:IPR040720 psi-mi:"MI:0469"(intact) crc64:509A5DEDDEE98823 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mGjvEcQ/ZVHp/P+89KaQ7DrjcQg559292 rogid:8STCUe6Ie2CnTTBMjY8wrld5h44559292 intact-crc:955B4179F0D35385|rigid:nlz+S3GfeaZlD3J0q+pf4KqPgro false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02785 uniprotkb:P38227 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C intact:EBI-21433|uniprotkb:D6VQ43|ensemblfungi:YBR043C psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:qdr3_yeast(display_long)|uniprotkb:AQR2(gene name synonym)|uniprotkb:YBR0413(orf name)|uniprotkb:YBR043C(locus name)|uniprotkb:QDR3(gene name)|psi-mi:QDR3(display_short)|uniprotkb:Acids quinidine resistance protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327561|imex:IM-14275-1240 author score:99.34 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) refseq:NP_009599.2|sgd:S000000247|mint:P38227|dip:DIP-797N|ensemblfungi:YBR043C(gene)|ensemblfungi:YBR043C_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0010509"(polyamine homeostasis)|go:"GO:0015203"(polyamine transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - crc64:AA2C5D2D7175F176 figure legend:tables S3 and S4|author-confidence:99.34|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 rogid:MMz3uLAC9N04/dbLWanOpe6Ergk559292 intact-crc:B4FCDD8B9739FA89|rigid:963q1Jw13NgWAFF1OU1OlL4A+HA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38236 uniprotkb:P38236 intact:EBI-11619|ensemblfungi:YBR057C|uniprotkb:D6VQ56 intact:EBI-11619|ensemblfungi:YBR057C|uniprotkb:D6VQ56 psi-mi:mum2_yeast(display_long)|uniprotkb:MUM2(gene name)|psi-mi:MUM2(display_short)|uniprotkb:YBR057C(locus name)|uniprotkb:YBR0514(orf name)|uniprotkb:Muddled meiosis protein 2(gene name synonym) psi-mi:mum2_yeast(display_long)|uniprotkb:MUM2(gene name)|psi-mi:MUM2(display_short)|uniprotkb:YBR057C(locus name)|uniprotkb:YBR0514(orf name)|uniprotkb:Muddled meiosis protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327572|imex:IM-14275-1241 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBR057C(gene)|ensemblfungi:YBR057C_mRNA(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0080009"(mRNA methylation)|go:"GO:2000221"(negative regulation of pseudohyphal growth)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR029732|sgd:S000000261|refseq:NP_009613.1|mint:P38236|dip:DIP-1299N ensemblfungi:YBR057C(gene)|ensemblfungi:YBR057C_mRNA(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0080009"(mRNA methylation)|go:"GO:2000221"(negative regulation of pseudohyphal growth)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR029732|sgd:S000000261|refseq:NP_009613.1|mint:P38236|dip:DIP-1299N psi-mi:"MI:0469"(intact) crc64:E57C853BFE8E5E83 crc64:E57C853BFE8E5E83 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FIVaaQ/aQZ6QuuEo5z1f/NwwQi4559292 rogid:FIVaaQ/aQZ6QuuEo5z1f/NwwQi4559292 intact-crc:827C262237C52C9E|rigid:ZDtnYCLpDWr3Z99hWqaKfsgnXn4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06680 uniprotkb:P38260 intact:EBI-4799|uniprotkb:D6VSV8|ensemblfungi:YDR325W intact:EBI-21563|uniprotkb:D6VQA0|ensemblfungi:YBR101C psi-mi:cnd3_yeast(display_long)|uniprotkb:YCG1(gene name)|psi-mi:YCG1(display_short)|uniprotkb:YCS5(gene name synonym)|uniprotkb:YDR325W(locus name)|uniprotkb:CAPG homolog(gene name synonym) psi-mi:fes1_yeast(display_long)|uniprotkb:YBR101C(locus name)|uniprotkb:YBR0830(orf name)|uniprotkb:Factor exchange for SSA1 protein 1(gene name synonym)|uniprotkb:FES1(gene name)|psi-mi:FES1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327583|imex:IM-14275-1242 author score:99.24 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025977|refseq:NP_010612.2|sgd:S000002733|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027165|mint:Q06680|ensemblfungi:YDR325W(gene)|ensemblfungi:YDR325W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0051301"(cell division)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0070058"(tRNA gene clustering)|go:"GO:0070550"(rDNA condensation)|go:"GO:1903342"(negative regulation of meiotic DNA double-strand break formation)|rcsb pdb:5OQN|rcsb pdb:5OQO|rcsb pdb:5OQP|rcsb pdb:5OQQ|rcsb pdb:6YVD|reactome:R-SCE-2514853 sgd:S000000305|refseq:NP_009659.3|mint:P38260|dip:DIP-4918N|ensemblfungi:YBR101C(gene)|ensemblfungi:YBR101C_mRNA(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013918(Nucleotide exchange factor Fes1)|interpro:IPR016024(Armadillo-type fold) psi-mi:"MI:0469"(intact) - crc64:4A50D069625BA500 figure legend:tables S3 and S4|author-confidence:99.24|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:JIB7v/r49Qej3BgQ3v1NYevEkN4559292 rogid:swXhGbIfsVTGs+eOqqViPwySpI0559292 intact-crc:5E89E15DEA8F4F42|rigid:/WBjy3oRVhZGY/+FtyUQcARKXKo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38261 uniprotkb:P32855 intact:EBI-21567|uniprotkb:D6VQA1|ensemblfungi:YBR102C intact:EBI-16896|uniprotkb:D6W461|ensemblfungi:YPR055W psi-mi:exo84_yeast(display_long)|uniprotkb:YBR102C(locus name)|uniprotkb:YBR0831(orf name)|uniprotkb:Exocyst complex protein of 84 kDa(gene name synonym)|uniprotkb:EXO84(gene name)|psi-mi:EXO84(display_short)|uniprotkb:USA3(gene name synonym)|uniprotkb:U1 SNP1-associating protein 3(gene name synonym) psi-mi:sec8_yeast(display_long)|uniprotkb:SEC8(gene name)|psi-mi:SEC8(display_short)|uniprotkb:YP9499.11(orf name)|uniprotkb:YPR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327594|imex:IM-14275-1243 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009660.1|sgd:S000000306|mint:P38261|dip:DIP-2732N|ensemblfungi:YBR102C(gene)|ensemblfungi:YBR102C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000145"(exocyst)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0001927"(exocyst assembly)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0043332"(mating projection tip)|go:"GO:0051601"(exocyst localization)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|rcsb pdb:2D2S|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876 ensemblfungi:YPR055W(gene)|ensemblfungi:YPR055W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000145"(exocyst)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0043332"(mating projection tip)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR007191(Sec8 exocyst complex component specific domain)|interpro:IPR039682|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876|refseq:NP_015380.1|sgd:S000006259|dip:DIP-2937N|mint:P32855 psi-mi:"MI:0469"(intact) crc64:1BCDE834466C3536 crc64:96FC3139850C07F3 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tJ29//zd8m0QGJu94oH597pBVTg559292 rogid:BMjRtok7YmXgRxvs1Z6QvH/QtqU559292 intact-crc:D75ADF08B2FEA6A0|rigid:ZZaq393wB31z8EzlOgbiWN7cz7E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38261 uniprotkb:P38261 intact:EBI-21567|uniprotkb:D6VQA1|ensemblfungi:YBR102C intact:EBI-21567|uniprotkb:D6VQA1|ensemblfungi:YBR102C psi-mi:exo84_yeast(display_long)|uniprotkb:YBR102C(locus name)|uniprotkb:YBR0831(orf name)|uniprotkb:Exocyst complex protein of 84 kDa(gene name synonym)|uniprotkb:EXO84(gene name)|psi-mi:EXO84(display_short)|uniprotkb:USA3(gene name synonym)|uniprotkb:U1 SNP1-associating protein 3(gene name synonym) psi-mi:exo84_yeast(display_long)|uniprotkb:YBR102C(locus name)|uniprotkb:YBR0831(orf name)|uniprotkb:Exocyst complex protein of 84 kDa(gene name synonym)|uniprotkb:EXO84(gene name)|psi-mi:EXO84(display_short)|uniprotkb:USA3(gene name synonym)|uniprotkb:U1 SNP1-associating protein 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327605|imex:IM-14275-1244 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009660.1|sgd:S000000306|mint:P38261|dip:DIP-2732N|ensemblfungi:YBR102C(gene)|ensemblfungi:YBR102C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000145"(exocyst)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0001927"(exocyst assembly)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0043332"(mating projection tip)|go:"GO:0051601"(exocyst localization)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|rcsb pdb:2D2S|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876 refseq:NP_009660.1|sgd:S000000306|mint:P38261|dip:DIP-2732N|ensemblfungi:YBR102C(gene)|ensemblfungi:YBR102C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000145"(exocyst)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0001927"(exocyst assembly)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0043332"(mating projection tip)|go:"GO:0051601"(exocyst localization)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|rcsb pdb:2D2S|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876 psi-mi:"MI:0469"(intact) crc64:1BCDE834466C3536 crc64:1BCDE834466C3536 figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tJ29//zd8m0QGJu94oH597pBVTg559292 rogid:tJ29//zd8m0QGJu94oH597pBVTg559292 intact-crc:5D903EF8552EC420|rigid:n1jixqtl28wrvUYr63jKSZSkx1Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38261 uniprotkb:P89102 intact:EBI-21567|uniprotkb:D6VQA1|ensemblfungi:YBR102C intact:EBI-16865|uniprotkb:Q03775|uniprotkb:Q04128|uniprotkb:D6VSE6|ensemblfungi:YDR166C psi-mi:exo84_yeast(display_long)|uniprotkb:YBR102C(locus name)|uniprotkb:YBR0831(orf name)|uniprotkb:Exocyst complex protein of 84 kDa(gene name synonym)|uniprotkb:EXO84(gene name)|psi-mi:EXO84(display_short)|uniprotkb:USA3(gene name synonym)|uniprotkb:U1 SNP1-associating protein 3(gene name synonym) psi-mi:sec5_yeast(display_long)|uniprotkb:YD8358.20C(orf name)|uniprotkb:SEC5(gene name)|psi-mi:SEC5(display_short)|uniprotkb:YD9489.01C(orf name)|uniprotkb:YDR166C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327616|imex:IM-14275-1245 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009660.1|sgd:S000000306|mint:P38261|dip:DIP-2732N|ensemblfungi:YBR102C(gene)|ensemblfungi:YBR102C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000145"(exocyst)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0001927"(exocyst assembly)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0043332"(mating projection tip)|go:"GO:0051601"(exocyst localization)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|rcsb pdb:2D2S|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876 refseq:NP_010450.3|ensemblfungi:YDR166C(gene)|ensemblfungi:YDR166C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000145"(exocyst)|go:"GO:0001927"(exocyst assembly)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0043332"(mating projection tip)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0071944"(cell periphery)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR029175|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876|interpro:IPR039481|sgd:S000002573|dip:DIP-2579N|mint:P89102 psi-mi:"MI:0469"(intact) crc64:1BCDE834466C3536 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tJ29//zd8m0QGJu94oH597pBVTg559292 rogid:SWV3HuxYf2DehDadp3hAPEELUTU559292 intact-crc:A99C4B55573C137A|rigid:LXbqETp2ZIfJX/Pk+mJa6BrHpuY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06245 uniprotkb:P38261 intact:EBI-16504|uniprotkb:P87329|uniprotkb:D6VYH2|ensemblfungi:YLR166C intact:EBI-21567|uniprotkb:D6VQA1|ensemblfungi:YBR102C psi-mi:sec10_yeast(display_long)|uniprotkb:SEC10(gene name)|psi-mi:SEC10(display_short)|uniprotkb:L9362.12(orf name)|uniprotkb:YLR166C(locus name) psi-mi:exo84_yeast(display_long)|uniprotkb:YBR102C(locus name)|uniprotkb:YBR0831(orf name)|uniprotkb:Exocyst complex protein of 84 kDa(gene name synonym)|uniprotkb:EXO84(gene name)|psi-mi:EXO84(display_short)|uniprotkb:USA3(gene name synonym)|uniprotkb:U1 SNP1-associating protein 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327627|imex:IM-14275-1246 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-SCE-264876|ensemblfungi:YLR166C(gene)|ensemblfungi:YLR166C_mRNA(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0043332"(mating projection tip)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR009976(Exocyst complex component Sec10)|interpro:IPR033960|rcsb pdb:5YFP|rcsb pdb:6VKL|refseq:NP_013267.1|sgd:S000004156|dip:DIP-1724N|mint:Q06245 refseq:NP_009660.1|sgd:S000000306|mint:P38261|dip:DIP-2732N|ensemblfungi:YBR102C(gene)|ensemblfungi:YBR102C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000145"(exocyst)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0001927"(exocyst assembly)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0043332"(mating projection tip)|go:"GO:0051601"(exocyst localization)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|rcsb pdb:2D2S|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876 psi-mi:"MI:0469"(intact) crc64:A32073099815388D crc64:1BCDE834466C3536 figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:PnkfUb1WnBvWIenaLMDEEcf919o559292 rogid:tJ29//zd8m0QGJu94oH597pBVTg559292 intact-crc:BC1325C660F3145D|rigid:OUjaOYqLcGIWj3NQeSHQkISRPJE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:P10614 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327638|imex:IM-14275-1247 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:FF1D95AE6D69922E|rigid:jJzGgVOVB2Gwn0cU8ARDwuEJJhg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15365 uniprotkb:P38264 intact:EBI-5527|uniprotkb:D6VWX1|ensemblfungi:YJR152W intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 psi-mi:dal5_yeast(display_long)|uniprotkb:DAL5(gene name)|psi-mi:DAL5(display_short)|uniprotkb:UREP1(gene name synonym)|uniprotkb:YJR152W(locus name)|uniprotkb:J2230(orf name) psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327649|imex:IM-14275-1248 author score:98.18 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003913|refseq:NP_012686.3|dip:DIP-7873N|mint:P15365|ensemblfungi:YJR152W(gene)|ensemblfungi:YJR152W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015124"(allantoate transmembrane transporter activity)|go:"GO:0015719"(allantoate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0042938"(dipeptide transport)|go:"GO:0042939"(tripeptide transport)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.18|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Y2kCv3dK4Hjn9hJpK+WK5rp6VKU559292 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 intact-crc:1D60A3FFCE843872|rigid:tm9yLP67Begn4mvOQ+Vn/TlbMsw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:P17064 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-2047850|uniprotkb:D3DLV9|ensemblfungi:YER056C psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:fcy2_yeast(display_long)|uniprotkb:Cytosine/purine transport protein FCY2(gene name synonym)|uniprotkb:Fluorocytosine resistance protein 2(gene name synonym)|uniprotkb:YER056C(locus name)|uniprotkb:FCY2(gene name)|psi-mi:FCY2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327660|imex:IM-14275-1249 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N refseq:NP_010976.1|sgd:S000000858|dip:DIP-7593N|mint:P17064|ensemblfungi:YER056C(gene)|ensemblfungi:YER056C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015205"(nucleobase transmembrane transporter activity)|go:"GO:0015212"(cytidine transmembrane transporter activity)|go:"GO:0015856"(cytosine transport)|go:"GO:0015861"(cytidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:0072530"(purine-containing compound transmembrane transport)|interpro:IPR001248(Permease for cytosine/purines, uracil, thiamine, allantoin)|interpro:IPR012681(Nucleobase cation symporter-1, NCS1)|interpro:IPR026030 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:797s9w2xSSBhW0uTLcFEESToqgg559292 intact-crc:64A15F8972406EC0|rigid:93oOlnrmCU5oPvyH4Ea20PmHORo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21825 uniprotkb:P38264 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327671|imex:IM-14275-1250 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 intact-crc:7399452A7EE9E0AD|rigid:Vy4DrSwIr+HdmNtIiQ+VlRmbCIo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:P28496 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-26585|uniprotkb:D6VXS8|ensemblfungi:YKL008C psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:lac1_yeast(display_long)|uniprotkb:LAC1(gene name)|psi-mi:LAC1(display_short)|uniprotkb:DGT1(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase LAC1(gene name synonym)|uniprotkb:YKL156(orf name)|uniprotkb:YKL008C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327682|imex:IM-14275-1251 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N sgd:S000001491|refseq:NP_012917.3|mint:P28496|dip:DIP-4348N|ensemblfungi:YKL008C(gene)|ensemblfungi:YKL008C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0034399"(nuclear periphery)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:0061576"(acyl-CoA ceramide synthase complex)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR013599(TRAM1-like protein)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|reactome:R-SCE-1660661 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:gqRCCAHQcrRAHNO+R2LkQOzJ0mg559292 intact-crc:C4FE3CFE9178317D|rigid:c1UgtrBXIezs8O4u7Ue3RkHZ+jQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:P38264 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327693|imex:IM-14275-1252 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 intact-crc:BB6274B60D2B1525|rigid:xQENi2M1TzIYnYEO9s3OOwiXJUU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:P36076 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327704|imex:IM-14275-1253 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:Li7vZOassm4PC5fW111/j5ivgEc559292 intact-crc:0B44FFEFCE0E2368|rigid:nZvwV6qesVtrFWJ7gbY8GytyOz8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:P38264 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327715|imex:IM-14275-1254 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 intact-crc:69CA6D40AE241A6D|rigid:sOMT+B4kv3aZsTdNdLjjk7eUP+Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:P38353 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-18175|uniprotkb:D6VQS8|ensemblfungi:YBR283C psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:ssh1_yeast(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:Ssh1 complex subunit alpha(gene name synonym)|uniprotkb:Ssh1 complex subunit SSH1(gene name synonym)|uniprotkb:YBR2020(orf name)|uniprotkb:YBR283C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327726|imex:IM-14275-1255 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N refseq:NP_009842.1|sgd:S000000487|ensemblfungi:YBR283C(gene)|ensemblfungi:YBR283C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:2WW9|rcsb pdb:2WWA|dip:DIP-4962N|mint:P38353 psi-mi:"MI:0469"(intact) - crc64:48267EEA3E0191BD figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:76wvZIdv7W5BQn6wI+sHOGQAyuc559292 intact-crc:3B54C81636A1B8D5|rigid:++pWfRv5ofY9EKjvcW+OpFe9o3k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:P39543 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-26193|uniprotkb:D6VVZ9|ensemblfungi:YJL192C psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:sop4_yeast(display_long)|uniprotkb:Suppressor of PMA1-7 protein 4(gene name synonym)|uniprotkb:YJL192C(locus name)|uniprotkb:J0351(orf name)|uniprotkb:SOP4(gene name)|psi-mi:SOP4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327737|imex:IM-14275-1256 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N sgd:S000003728|refseq:NP_012343.1|mint:P39543|dip:DIP-5094N|ensemblfungi:YJL192C(gene)|ensemblfungi:YJL192C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR031395|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:a+WulVpSm4gdxpcINNvDPLR2rZI559292 intact-crc:6653E1D4935BB697|rigid:LRlpI81qNMTVgWwyE2jNDsGOEZY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:P40540 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327748|imex:IM-14275-1257 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) - crc64:6DBEEEE7722203B0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 intact-crc:91531BAA123A7292|rigid:EeZRxp2gNslcVglc6K3ABdZB78o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:P47155 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-2051644|uniprotkb:D6VWT7|ensemblfungi:YJR118C psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:ilm1_yeast(display_long)|uniprotkb:Increased loss of mitochondrial DNA protein 1(gene name synonym)|uniprotkb:J2033(orf name)|uniprotkb:ILM1(gene name)|psi-mi:ILM1(display_short)|uniprotkb:YJR118C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327759|imex:IM-14275-1258 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N sgd:S000003879|interpro:IPR018815|refseq:NP_012652.3|mint:P47155|ensemblfungi:YJR118C(gene)|ensemblfungi:YJR118C_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:BrQhbXGvUjNG6Bt5c0J7T8qzMeI559292 intact-crc:22284D658593C4E3|rigid:tWgxZ+tA+8z7wUvMerPE0ys31JY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53283 uniprotkb:P38264 intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327770|imex:IM-14275-1259 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 intact-crc:F383F82B70C87B61|rigid:y0li6KfPk5zOauC/WQjQrordZrs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:P54837 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327781|imex:IM-14275-1260 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:FE6E23D3DC142A91|rigid:W2MpBygtSg3aKQ7nJ/QcL76EBJI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:Q02774 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327792|imex:IM-14275-1261 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 intact-crc:29A4F318A4648513|rigid:d9wlPRNK9BLh6TNvUWqwYtj4Lg4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:P38264 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327803|imex:IM-14275-1262 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 intact-crc:E4F737FB7601DD27|rigid:7+V0l+B48EoxTpcxuMNseEkBOy8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:Q06144 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327814|imex:IM-14275-1263 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:2F474503CAB7C195 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 intact-crc:A75EBCED10F2DD5F|rigid:Vlhzqty0KlkEIUjV/2OLEpVoYuU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:Q06451 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-34275|uniprotkb:D6W4F2|ensemblfungi:YPR156C psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:tpo3_yeast(display_long)|uniprotkb:TPO3(gene name)|psi-mi:TPO3(display_short)|uniprotkb:P9584.7(orf name)|uniprotkb:YPR156C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327825|imex:IM-14275-1264 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N refseq:NP_015482.1|sgd:S000006360|mint:Q06451|dip:DIP-3907N|ensemblfungi:YPR156C(gene)|ensemblfungi:YPR156C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - crc64:D260ED161F800502 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:oVpx7Bjk/mK2Q7+/j05tX3gHw7k559292 intact-crc:D5480305A34CBC23|rigid:jCbfwxWeXlU/JH2maSH1A0IOmH8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99287 uniprotkb:P38264 intact:EBI-37523|uniprotkb:D6W2M3|ensemblfungi:YOR165W intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 psi-mi:sey1_yeast(display_long)|uniprotkb:SEY1(gene name)|psi-mi:SEY1(display_short)|uniprotkb:YOR165W(locus name)|uniprotkb:Synthetic enhancer of YOP1 protein(gene name synonym)|uniprotkb:O3590(orf name) psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327836|imex:IM-14275-1265 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014808.1|sgd:S000005691|dip:DIP-49373N|mint:Q99287|ensemblfungi:YOR165W(gene)|ensemblfungi:YOR165W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0061024"(membrane organization)|go:"GO:0071944"(cell periphery)|interpro:IPR008803(Root hair defective 3 GTP-binding)|interpro:IPR027417|interpro:IPR030386 refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N psi-mi:"MI:0469"(intact) crc64:DEC0C9EC3AB172DF - figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zFsgalfyUvAuuV51vChJjraiQmI559292 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 intact-crc:F4B3C6518F25B3F4|rigid:bPDn1qUo/BcEZQJZfuxtGXYrxgM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38272 uniprotkb:P32492 intact:EBI-21600|uniprotkb:D6VQC7|ensemblfungi:YBR130C intact:EBI-11681|ensemblfungi:YAL029C|uniprotkb:D6VPI9 psi-mi:she3_yeast(display_long)|uniprotkb:YBR1005(orf name)|uniprotkb:YBR130C(locus name)|uniprotkb:SHE3(gene name)|psi-mi:SHE3(display_short) psi-mi:myo4_yeast(display_long)|uniprotkb:MYO4(gene name)|psi-mi:MYO4(display_short)|uniprotkb:SHE1(gene name synonym)|uniprotkb:YAL029C(locus name)|uniprotkb:FUN22(orf name)|uniprotkb:SWI5-dependent HO expression protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327847|imex:IM-14275-1266 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000334|refseq:NP_009688.3|mint:P38272|dip:DIP-2037N|ensemblfungi:YBR130C(gene)|ensemblfungi:YBR130C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0051028"(mRNA transport)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR031398|rcsb pdb:4LL7|rcsb pdb:4LL8|rcsb pdb:4WNL|rcsb pdb:5M0I|rcsb pdb:5M0J go:"GO:0007015"(actin filament organization)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002710(Dilute)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036103|interpro:IPR036961|rcsb pdb:3MMI|rcsb pdb:4LL6|rcsb pdb:4LL8|reactome:R-SCE-190873|reactome:R-SCE-9013419|reactome:R-SCE-9013425|ensemblfungi:YAL029C(gene)|ensemblfungi:YAL029C_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|refseq:NP_009373.1|sgd:S000000027|mint:P32492|dip:DIP-5761N psi-mi:"MI:0469"(intact) crc64:590404D2E140BB7A crc64:E79C0FE72B041E95 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HmP1/ozLaDCRVBA9eJ10x7CYNjI559292 rogid:jxx/cStiu7zpcGFLmoTedhHVZcY559292 intact-crc:4B84F776FF824D44|rigid:eeZUdGg1c631m7Ik/dqUfpLlR5g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36068 uniprotkb:P38272 intact:EBI-26866|uniprotkb:D6VX65|ensemblfungi:YKL130C intact:EBI-21600|uniprotkb:D6VQC7|ensemblfungi:YBR130C psi-mi:she2_yeast(display_long)|uniprotkb:YKL130C(locus name)|uniprotkb:SHE2(gene name)|psi-mi:SHE2(display_short) psi-mi:she3_yeast(display_long)|uniprotkb:YBR1005(orf name)|uniprotkb:YBR130C(locus name)|uniprotkb:SHE3(gene name)|psi-mi:SHE3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327858|imex:IM-14275-1267 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012792.1|sgd:S000001613|mint:P36068|dip:DIP-1206N|ensemblfungi:YKL130C(gene)|ensemblfungi:YKL130C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005934"(cellular bud tip)|go:"GO:0007533"(mating type switching)|go:"GO:0008289"(lipid binding)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0051028"(mRNA transport)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR024261|interpro:IPR036827|rcsb pdb:1XLY|rcsb pdb:4WNL|rcsb pdb:5M0I|rcsb pdb:5M0J sgd:S000000334|refseq:NP_009688.3|mint:P38272|dip:DIP-2037N|ensemblfungi:YBR130C(gene)|ensemblfungi:YBR130C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0051028"(mRNA transport)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR031398|rcsb pdb:4LL7|rcsb pdb:4LL8|rcsb pdb:4WNL|rcsb pdb:5M0I|rcsb pdb:5M0J psi-mi:"MI:0469"(intact) crc64:5514B374655EFDBB crc64:590404D2E140BB7A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UkbzQaIhI+P2wZVxpnoMFUj0gGo559292 rogid:HmP1/ozLaDCRVBA9eJ10x7CYNjI559292 intact-crc:3AEDCEDE5476F8C8|rigid:CZvBj73ZBs9GqFjlnOKp9zEa+Rg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38272 uniprotkb:P38272 intact:EBI-21600|uniprotkb:D6VQC7|ensemblfungi:YBR130C intact:EBI-21600|uniprotkb:D6VQC7|ensemblfungi:YBR130C psi-mi:she3_yeast(display_long)|uniprotkb:YBR1005(orf name)|uniprotkb:YBR130C(locus name)|uniprotkb:SHE3(gene name)|psi-mi:SHE3(display_short) psi-mi:she3_yeast(display_long)|uniprotkb:YBR1005(orf name)|uniprotkb:YBR130C(locus name)|uniprotkb:SHE3(gene name)|psi-mi:SHE3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327869|imex:IM-14275-1268 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000334|refseq:NP_009688.3|mint:P38272|dip:DIP-2037N|ensemblfungi:YBR130C(gene)|ensemblfungi:YBR130C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0051028"(mRNA transport)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR031398|rcsb pdb:4LL7|rcsb pdb:4LL8|rcsb pdb:4WNL|rcsb pdb:5M0I|rcsb pdb:5M0J sgd:S000000334|refseq:NP_009688.3|mint:P38272|dip:DIP-2037N|ensemblfungi:YBR130C(gene)|ensemblfungi:YBR130C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0051028"(mRNA transport)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR031398|rcsb pdb:4LL7|rcsb pdb:4LL8|rcsb pdb:4WNL|rcsb pdb:5M0I|rcsb pdb:5M0J psi-mi:"MI:0469"(intact) crc64:590404D2E140BB7A crc64:590404D2E140BB7A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HmP1/ozLaDCRVBA9eJ10x7CYNjI559292 rogid:HmP1/ozLaDCRVBA9eJ10x7CYNjI559292 intact-crc:5062EE84DF9003DD|rigid:ZclbtO2FbW2MPaxAy8JwtOThCmw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38272 uniprotkb:P40414 intact:EBI-21600|uniprotkb:D6VQC7|ensemblfungi:YBR130C intact:EBI-19419|uniprotkb:D6VVE8|ensemblfungi:YIL138C psi-mi:she3_yeast(display_long)|uniprotkb:YBR1005(orf name)|uniprotkb:YBR130C(locus name)|uniprotkb:SHE3(gene name)|psi-mi:SHE3(display_short) psi-mi:tpm2_yeast(display_long)|uniprotkb:YIL138C(locus name)|uniprotkb:TPM2(gene name)|psi-mi:TPM2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327880|imex:IM-14275-1269 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000334|refseq:NP_009688.3|mint:P38272|dip:DIP-2037N|ensemblfungi:YBR130C(gene)|ensemblfungi:YBR130C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0051028"(mRNA transport)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR031398|rcsb pdb:4LL7|rcsb pdb:4LL8|rcsb pdb:4WNL|rcsb pdb:5M0I|rcsb pdb:5M0J sgd:S000001400|ensemblfungi:YIL138C(gene)|ensemblfungi:YIL138C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003786"(actin lateral binding)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005884"(actin filament)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|interpro:IPR000533(Tropomyosin)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007119"(budding cell isotropic bud growth)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0032432"(actin filament bundle)|refseq:NP_012128.3|dip:DIP-2201N|mint:P40414 psi-mi:"MI:0469"(intact) crc64:590404D2E140BB7A - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HmP1/ozLaDCRVBA9eJ10x7CYNjI559292 rogid:/V6RhsoBaanxDVJ4SSAfev2tvnk559292 intact-crc:2DA635B7BBD72306|rigid:tlc7MRpuqQNBNnZOFTfVhJbHOow false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C268 uniprotkb:P38295 intact:EBI-2044092|uniprotkb:D6VPV9|ensemblfungi:YBL039W-B intact:EBI-20890|uniprotkb:D6VQH2|ensemblfungi:YBR177C psi-mi:yb39b_yeast(display_long)|uniprotkb:YBL039W-B(locus name) psi-mi:mcfs2_yeast(display_long)|uniprotkb:YBR177C(locus name)|uniprotkb:YBR1239(orf name)|uniprotkb:EHT1(gene name)|psi-mi:EHT1(display_short)|uniprotkb:Alcohol O-acetyltransferase(gene name synonym)|uniprotkb:Ethanol hexanoyl transferase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327891|imex:IM-14275-1270 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000028517|refseq:NP_878045.1|mint:P0C268|ensemblfungi:YBL039W-B(gene)|ensemblfungi:YBL039W-B_mRNA(transcript)|go:"GO:0005777"(peroxisome) refseq:NP_009736.3|sgd:S000000381|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|mint:P38295|interpro:IPR029058|ensemblfungi:YBR177C(gene)|ensemblfungi:YBR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034319"(alcohol O-butanoyltransferase activity)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|reactome:R-SCE-1483191 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:EfowKSHyZ6Fgw3vWQ74mzPwXTbQ559292 rogid:9arzlcrZmkK0VXN7Zw87dAe1Txc559292 intact-crc:3EB61CCBEB40F06E|rigid:5HawzerrFAo/9WGlebGL5CXzqVY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38295 uniprotkb:P10614 intact:EBI-20890|uniprotkb:D6VQH2|ensemblfungi:YBR177C intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:mcfs2_yeast(display_long)|uniprotkb:YBR177C(locus name)|uniprotkb:YBR1239(orf name)|uniprotkb:EHT1(gene name)|psi-mi:EHT1(display_short)|uniprotkb:Alcohol O-acetyltransferase(gene name synonym)|uniprotkb:Ethanol hexanoyl transferase 1(gene name synonym) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327902|imex:IM-14275-1271 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009736.3|sgd:S000000381|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|mint:P38295|interpro:IPR029058|ensemblfungi:YBR177C(gene)|ensemblfungi:YBR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034319"(alcohol O-butanoyltransferase activity)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|reactome:R-SCE-1483191 refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9arzlcrZmkK0VXN7Zw87dAe1Txc559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:6CC779E08B4BA313|rigid:98Drji2C/H8Wkr1l5ZtufFSgSS8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38295 uniprotkb:P11986 intact:EBI-20890|uniprotkb:D6VQH2|ensemblfungi:YBR177C intact:EBI-9257|ensemblfungi:YJL153C|uniprotkb:D6VW34 psi-mi:mcfs2_yeast(display_long)|uniprotkb:YBR177C(locus name)|uniprotkb:YBR1239(orf name)|uniprotkb:EHT1(gene name)|psi-mi:EHT1(display_short)|uniprotkb:Alcohol O-acetyltransferase(gene name synonym)|uniprotkb:Ethanol hexanoyl transferase 1(gene name synonym) psi-mi:ino1_yeast(display_long)|uniprotkb:INO1(gene name)|psi-mi:INO1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym)|uniprotkb:J0610(orf name)|uniprotkb:YJL153C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327913|imex:IM-14275-1272 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009736.3|sgd:S000000381|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|mint:P38295|interpro:IPR029058|ensemblfungi:YBR177C(gene)|ensemblfungi:YBR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034319"(alcohol O-butanoyltransferase activity)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|reactome:R-SCE-1483191 rcsb pdb:1P1K|ensemblfungi:YJL153C(gene)|ensemblfungi:YJL153C_mRNA(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|rcsb pdb:1JKF|rcsb pdb:1JKI|rcsb pdb:1LA2|rcsb pdb:1P1F|rcsb pdb:1P1H|rcsb pdb:1P1I|rcsb pdb:1P1J|rcsb pdb:1RM0|reactome:R-SCE-1855183|refseq:NP_012382.2|sgd:S000003689|dip:DIP-5687N|mint:P11986 psi-mi:"MI:0469"(intact) - crc64:282E2AE5D156289D figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9arzlcrZmkK0VXN7Zw87dAe1Txc559292 rogid:3OB3q28fOVxXSBMwMpLe2c1g8p8559292 intact-crc:58A17EF8D8F4FBD0|rigid:hEGn1TPtEowCcRp3s5NTwgZXmUA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:P38295 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-20890|uniprotkb:D6VQH2|ensemblfungi:YBR177C psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:mcfs2_yeast(display_long)|uniprotkb:YBR177C(locus name)|uniprotkb:YBR1239(orf name)|uniprotkb:EHT1(gene name)|psi-mi:EHT1(display_short)|uniprotkb:Alcohol O-acetyltransferase(gene name synonym)|uniprotkb:Ethanol hexanoyl transferase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327924|imex:IM-14275-1273 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD refseq:NP_009736.3|sgd:S000000381|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|mint:P38295|interpro:IPR029058|ensemblfungi:YBR177C(gene)|ensemblfungi:YBR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034319"(alcohol O-butanoyltransferase activity)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|reactome:R-SCE-1483191 psi-mi:"MI:0469"(intact) crc64:DBA26AF5B769C02A - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:9arzlcrZmkK0VXN7Zw87dAe1Txc559292 intact-crc:7EEA21573AFB2442|rigid:Qg5PrIe6G7EKXAeWsUcV+HFG3HE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:P38295 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-20890|uniprotkb:D6VQH2|ensemblfungi:YBR177C psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:mcfs2_yeast(display_long)|uniprotkb:YBR177C(locus name)|uniprotkb:YBR1239(orf name)|uniprotkb:EHT1(gene name)|psi-mi:EHT1(display_short)|uniprotkb:Alcohol O-acetyltransferase(gene name synonym)|uniprotkb:Ethanol hexanoyl transferase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327935|imex:IM-14275-1274 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N refseq:NP_009736.3|sgd:S000000381|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|mint:P38295|interpro:IPR029058|ensemblfungi:YBR177C(gene)|ensemblfungi:YBR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034319"(alcohol O-butanoyltransferase activity)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|reactome:R-SCE-1483191 psi-mi:"MI:0469"(intact) crc64:8B7F009521F72C15 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:9arzlcrZmkK0VXN7Zw87dAe1Txc559292 intact-crc:F470BA85C62F0B42|rigid:cxM0JZl4zO2lq9sF91BrCXCmcso false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28321 uniprotkb:P38295 intact:EBI-26790|uniprotkb:D6VXJ4|ensemblfungi:YKL094W intact:EBI-20890|uniprotkb:D6VQH2|ensemblfungi:YBR177C psi-mi:mgll_yeast(display_long)|uniprotkb:YJU3(gene name)|psi-mi:YJU3(display_short)|uniprotkb:Monoacylglycerol hydrolase(gene name synonym)|uniprotkb:Monoacylglycerol lipase(gene name synonym)|uniprotkb:Serine hydrolase YJU3(gene name synonym)|uniprotkb:YKL441(orf name)|uniprotkb:YKL094W(locus name)|uniprotkb:Fatty acid ethyl ester hydrolase(gene name synonym) psi-mi:mcfs2_yeast(display_long)|uniprotkb:YBR177C(locus name)|uniprotkb:YBR1239(orf name)|uniprotkb:EHT1(gene name)|psi-mi:EHT1(display_short)|uniprotkb:Alcohol O-acetyltransferase(gene name synonym)|uniprotkb:Ethanol hexanoyl transferase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327946|imex:IM-14275-1275 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022742|refseq:NP_012829.1|sgd:S000001577|mint:P28321|interpro:IPR029058|ensemblfungi:YKL094W(gene)|ensemblfungi:YKL094W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0071944"(cell periphery)|rcsb pdb:4ZWN|rcsb pdb:4ZXF refseq:NP_009736.3|sgd:S000000381|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|mint:P38295|interpro:IPR029058|ensemblfungi:YBR177C(gene)|ensemblfungi:YBR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034319"(alcohol O-butanoyltransferase activity)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|reactome:R-SCE-1483191 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IHpY1aez3MG+bn7bThCBdvE6KMw559292 rogid:9arzlcrZmkK0VXN7Zw87dAe1Txc559292 intact-crc:4207E4CF6D05BD88|rigid:ZB7YXakvPcoSaSQ8HNVP7Nt8YWI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38295 uniprotkb:P32610 intact:EBI-20890|uniprotkb:D6VQH2|ensemblfungi:YBR177C intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W psi-mi:mcfs2_yeast(display_long)|uniprotkb:YBR177C(locus name)|uniprotkb:YBR1239(orf name)|uniprotkb:EHT1(gene name)|psi-mi:EHT1(display_short)|uniprotkb:Alcohol O-acetyltransferase(gene name synonym)|uniprotkb:Ethanol hexanoyl transferase 1(gene name synonym) psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327957|imex:IM-14275-1276 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009736.3|sgd:S000000381|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|mint:P38295|interpro:IPR029058|ensemblfungi:YBR177C(gene)|ensemblfungi:YBR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034319"(alcohol O-butanoyltransferase activity)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|reactome:R-SCE-1483191 refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610 psi-mi:"MI:0469"(intact) - crc64:FDE93E1FAF0AEC5B figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9arzlcrZmkK0VXN7Zw87dAe1Txc559292 rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292 intact-crc:BC454F4EBD1DCB68|rigid:d9o3+K4OHULWWghU5rdGIWwNqMI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34163 uniprotkb:P38295 intact:EBI-19177|uniprotkb:D6VX56|ensemblfungi:YKL140W intact:EBI-20890|uniprotkb:D6VQH2|ensemblfungi:YBR177C psi-mi:tgl1_yeast(display_long)|uniprotkb:TGL1(gene name)|psi-mi:TGL1(display_short)|uniprotkb:YKL140W(locus name)|uniprotkb:YKL5(orf name)|uniprotkb:Triglyceride lipase-cholesterol esterase 1(gene name synonym) psi-mi:mcfs2_yeast(display_long)|uniprotkb:YBR177C(locus name)|uniprotkb:YBR1239(orf name)|uniprotkb:EHT1(gene name)|psi-mi:EHT1(display_short)|uniprotkb:Alcohol O-acetyltransferase(gene name synonym)|uniprotkb:Ethanol hexanoyl transferase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327968|imex:IM-14275-1277 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012782.1|sgd:S000001623|ensemblfungi:YKL140W(gene)|ensemblfungi:YKL140W_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR029058|dip:DIP-6306N|mint:P34163 refseq:NP_009736.3|sgd:S000000381|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|mint:P38295|interpro:IPR029058|ensemblfungi:YBR177C(gene)|ensemblfungi:YBR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034319"(alcohol O-butanoyltransferase activity)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|reactome:R-SCE-1483191 psi-mi:"MI:0469"(intact) crc64:32D1F230701CB083 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:/f3560MDciadPqvZ0iY9e9oVBH8559292 rogid:9arzlcrZmkK0VXN7Zw87dAe1Txc559292 intact-crc:A7EC1EA5640A2684|rigid:GYD1hwQFzgA2kAlIIXKJDbXbGr4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35180 uniprotkb:P38295 intact:EBI-12522|uniprotkb:D6VUL4|ensemblfungi:YGR082W intact:EBI-20890|uniprotkb:D6VQH2|ensemblfungi:YBR177C psi-mi:tom20_yeast(display_long)|uniprotkb:MOM19(gene name synonym)|uniprotkb:YGR082W(locus name)|uniprotkb:TOM20(gene name)|psi-mi:TOM20(display_short)|uniprotkb:MAS20(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 20 kDa subunit(gene name synonym)|uniprotkb:Protein MAS20(gene name synonym) psi-mi:mcfs2_yeast(display_long)|uniprotkb:YBR177C(locus name)|uniprotkb:YBR1239(orf name)|uniprotkb:EHT1(gene name)|psi-mi:EHT1(display_short)|uniprotkb:Alcohol O-acetyltransferase(gene name synonym)|uniprotkb:Ethanol hexanoyl transferase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327979|imex:IM-14275-1278 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR082W(gene)|ensemblfungi:YGR082W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR023392|refseq:NP_011596.1|sgd:S000003314|dip:DIP-2539N|mint:P35180 refseq:NP_009736.3|sgd:S000000381|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|mint:P38295|interpro:IPR029058|ensemblfungi:YBR177C(gene)|ensemblfungi:YBR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034319"(alcohol O-butanoyltransferase activity)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|reactome:R-SCE-1483191 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:7U00YLVWcaegWlJEKzGblv6STx4559292 rogid:9arzlcrZmkK0VXN7Zw87dAe1Txc559292 intact-crc:215CF1C99DE4536C|rigid:jNzbRZz/KjgWAXlgzEWVzrdECOo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38295 uniprotkb:P35196 intact:EBI-20890|uniprotkb:D6VQH2|ensemblfungi:YBR177C intact:EBI-14943|uniprotkb:D6VQ03|ensemblfungi:YBR002C psi-mi:mcfs2_yeast(display_long)|uniprotkb:YBR177C(locus name)|uniprotkb:YBR1239(orf name)|uniprotkb:EHT1(gene name)|psi-mi:EHT1(display_short)|uniprotkb:Alcohol O-acetyltransferase(gene name synonym)|uniprotkb:Ethanol hexanoyl transferase 1(gene name synonym) psi-mi:rer2_yeast(display_long)|uniprotkb:"Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific)"(gene name synonym)|uniprotkb:YBR0107(orf name)|uniprotkb:RER2(gene name)|psi-mi:RER2(display_short)|uniprotkb:YBR002C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6327990|imex:IM-14275-1279 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009736.3|sgd:S000000381|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|mint:P38295|interpro:IPR029058|ensemblfungi:YBR177C(gene)|ensemblfungi:YBR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034319"(alcohol O-butanoyltransferase activity)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|reactome:R-SCE-1483191 interpro:IPR036424|refseq:NP_009556.1|sgd:S000000206|interpro:IPR001441(Di-trans-poly-cis-decaprenylcistransferase)|interpro:IPR018520|ensemblfungi:YBR002C(gene)|ensemblfungi:YBR002C_mRNA(transcript)|go:"GO:0002094"(polyprenyltransferase activity)|go:"GO:0004659"(prenyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016094"(polyprenol biosynthetic process)|go:"GO:0019408"(dolichol biosynthetic process)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0045547"(dehydrodolichyl diphosphate synthase activity)|go:"GO:1904423"(dehydrodolichyl diphosphate synthase complex)|reactome:R-SCE-446199|mint:P35196 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9arzlcrZmkK0VXN7Zw87dAe1Txc559292 rogid:gVl9E/6GKqKsUp/5VLdT5XGbjUM559292 intact-crc:483DF1D2164C7B78|rigid:cO48788LZMs1RXZSJgOgENfC6c4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38295 uniprotkb:P35844 intact:EBI-20890|uniprotkb:D6VQH2|ensemblfungi:YBR177C intact:EBI-9648|ensemblfungi:YPL145C|uniprotkb:D6W3M4|uniprotkb:E9P8U8 psi-mi:mcfs2_yeast(display_long)|uniprotkb:YBR177C(locus name)|uniprotkb:YBR1239(orf name)|uniprotkb:EHT1(gene name)|psi-mi:EHT1(display_short)|uniprotkb:Alcohol O-acetyltransferase(gene name synonym)|uniprotkb:Ethanol hexanoyl transferase 1(gene name synonym) psi-mi:kes1_yeast(display_long)|uniprotkb:KES1(gene name)|psi-mi:KES1(display_short)|uniprotkb:OSH4(gene name synonym)|uniprotkb:Protein KES1(gene name synonym)|uniprotkb:LPI3C(orf name)|uniprotkb:P2614(orf name)|uniprotkb:YPL145C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328001|imex:IM-14275-1280 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009736.3|sgd:S000000381|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|mint:P38295|interpro:IPR029058|ensemblfungi:YBR177C(gene)|ensemblfungi:YBR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034319"(alcohol O-butanoyltransferase activity)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|reactome:R-SCE-1483191 ensemblfungi:YPL145C(gene)|ensemblfungi:YPL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035621"(ER to Golgi ceramide transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|rcsb pdb:1ZHT|rcsb pdb:1ZHW|rcsb pdb:1ZHX|rcsb pdb:1ZHY|rcsb pdb:1ZHZ|rcsb pdb:1ZI7|rcsb pdb:3SPW|rcsb pdb:4F4B|rcsb pdb:4FES|rcsb pdb:4JCH|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_015180.1|sgd:S000006066|dip:DIP-2867N|mint:P35844 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9arzlcrZmkK0VXN7Zw87dAe1Txc559292 rogid:6vsHrA4RScGr2+xmii0wiuvK1OM559292 intact-crc:4A4498DB5F3D4E72|rigid:IQYNbdrUefM9ldLpt+P69pwtY98 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38295 uniprotkb:P38225 intact:EBI-20890|uniprotkb:D6VQH2|ensemblfungi:YBR177C intact:EBI-6819|uniprotkb:O60021|uniprotkb:Q86ZS3|uniprotkb:D6VQ41|ensemblfungi:YBR041W psi-mi:mcfs2_yeast(display_long)|uniprotkb:YBR177C(locus name)|uniprotkb:YBR1239(orf name)|uniprotkb:EHT1(gene name)|psi-mi:EHT1(display_short)|uniprotkb:Alcohol O-acetyltransferase(gene name synonym)|uniprotkb:Ethanol hexanoyl transferase 1(gene name synonym) psi-mi:fat1_yeast(display_long)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:Very-long-chain acyl-CoA synthetase(gene name synonym)|uniprotkb:YBR0411(orf name)|uniprotkb:YBR041W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328012|imex:IM-14275-1281 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009736.3|sgd:S000000381|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|mint:P38295|interpro:IPR029058|ensemblfungi:YBR177C(gene)|ensemblfungi:YBR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034319"(alcohol O-butanoyltransferase activity)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|reactome:R-SCE-1483191 refseq:NP_009597.2|sgd:S000000245|mint:P38225|dip:DIP-5048N|ensemblfungi:YBR041W(gene)|ensemblfungi:YBR041W_mRNA(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0071944"(cell periphery)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR030310|interpro:IPR042099|reactome:R-SCE-159418|reactome:R-SCE-193368|reactome:R-SCE-193775|reactome:R-SCE-389599|reactome:R-SCE-6798695|reactome:R-SCE-804914|reactome:R-SCE-9033241 psi-mi:"MI:0469"(intact) - crc64:509A5DEDDEE98823 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9arzlcrZmkK0VXN7Zw87dAe1Txc559292 rogid:mGjvEcQ/ZVHp/P+89KaQ7DrjcQg559292 intact-crc:77557B32F9E761FD|rigid:KFkHwUMsAV6p02a/05WZr9ZbpD4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38604 uniprotkb:P38295 intact:EBI-6572|uniprotkb:Q92327|uniprotkb:D3DL21|ensemblfungi:YHR072W intact:EBI-20890|uniprotkb:D6VQH2|ensemblfungi:YBR177C psi-mi:erg7_yeast(display_long)|uniprotkb:Oxidosqualene--lanosterol cyclase(gene name synonym)|uniprotkb:2,3-epoxysqualene--lanosterol cyclase(gene name synonym)|uniprotkb:YHR072W(locus name)|uniprotkb:ERG7(gene name)|psi-mi:ERG7(display_short) psi-mi:mcfs2_yeast(display_long)|uniprotkb:YBR177C(locus name)|uniprotkb:YBR1239(orf name)|uniprotkb:EHT1(gene name)|psi-mi:EHT1(display_short)|uniprotkb:Alcohol O-acetyltransferase(gene name synonym)|uniprotkb:Ethanol hexanoyl transferase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328023|imex:IM-14275-1282 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011939.2|sgd:S000001114|mint:P38604|dip:DIP-8319N|ensemblfungi:YHR072W(gene)|ensemblfungi:YHR072W_mRNA(transcript)|go:"GO:0000250"(lanosterol synthase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016104"(triterpenoid biosynthetic process)|go:"GO:0042300"(beta-amyrin synthase activity)|interpro:IPR002365(Terpene synthase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR018333|interpro:IPR032696|interpro:IPR032697|reactome:R-SCE-191273 refseq:NP_009736.3|sgd:S000000381|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|mint:P38295|interpro:IPR029058|ensemblfungi:YBR177C(gene)|ensemblfungi:YBR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034319"(alcohol O-butanoyltransferase activity)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|reactome:R-SCE-1483191 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zqDPA3GvKWkMTmH97TcdF8HOHBU559292 rogid:9arzlcrZmkK0VXN7Zw87dAe1Txc559292 intact-crc:1561859AD1C08C30|rigid:cKSXq8DT2tA4Nji0HfC/B/wbE/w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38756 uniprotkb:P38295 intact:EBI-24431|uniprotkb:D3DKU6|ensemblfungi:YHR003C intact:EBI-20890|uniprotkb:D6VQH2|ensemblfungi:YBR177C psi-mi:tcd1_yeast(display_long)|uniprotkb:TCD1(gene name)|psi-mi:TCD1(display_short)|uniprotkb:"t(6)A37 dehydratase 1"(gene name synonym)|uniprotkb:YHR003C(locus name) psi-mi:mcfs2_yeast(display_long)|uniprotkb:YBR177C(locus name)|uniprotkb:YBR1239(orf name)|uniprotkb:EHT1(gene name)|psi-mi:EHT1(display_short)|uniprotkb:Alcohol O-acetyltransferase(gene name synonym)|uniprotkb:Ethanol hexanoyl transferase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328034|imex:IM-14275-1283 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011866.1|sgd:S000001045|dip:DIP-4417N|mint:P38756|ensemblfungi:YHR003C(gene)|ensemblfungi:YHR003C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008641"(ubiquitin-like modifier activating enzyme activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0061503"(tRNA threonylcarbamoyladenosine dehydratase)|go:"GO:0061504"(cyclic threonylcarbamoyladenosine biosynthetic process)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR035985 refseq:NP_009736.3|sgd:S000000381|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|mint:P38295|interpro:IPR029058|ensemblfungi:YBR177C(gene)|ensemblfungi:YBR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034319"(alcohol O-butanoyltransferase activity)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|reactome:R-SCE-1483191 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Mce7jBtBDJ9bSrw+cQDCbhK8DvY559292 rogid:9arzlcrZmkK0VXN7Zw87dAe1Txc559292 intact-crc:E16391482FBC304A|rigid:fjJqgjPIz4EuvgFA5VCpywiR5MQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39958 uniprotkb:P38295 intact:EBI-7517|uniprotkb:D3DM41|ensemblfungi:YER136W intact:EBI-20890|uniprotkb:D6VQH2|ensemblfungi:YBR177C psi-mi:gdi1_yeast(display_long)|uniprotkb:YER136W(locus name)|uniprotkb:GDI1(gene name)|psi-mi:GDI1(display_short)|uniprotkb:SEC19(gene name synonym)|uniprotkb:Secretory pathway GDP dissociation inhibitor(gene name synonym) psi-mi:mcfs2_yeast(display_long)|uniprotkb:YBR177C(locus name)|uniprotkb:YBR1239(orf name)|uniprotkb:EHT1(gene name)|psi-mi:EHT1(display_short)|uniprotkb:Alcohol O-acetyltransferase(gene name synonym)|uniprotkb:Ethanol hexanoyl transferase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328045|imex:IM-14275-1284 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011062.1|sgd:S000000938|mint:P39958|dip:DIP-785N|ensemblfungi:YER136W(gene)|ensemblfungi:YER136W_mRNA(transcript)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|rcsb pdb:1UKV|rcsb pdb:2BCG|rcsb pdb:3CPH|rcsb pdb:3CPI|rcsb pdb:3CPJ|reactome:R-SCE-6798695|reactome:R-SCE-8876198 refseq:NP_009736.3|sgd:S000000381|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|mint:P38295|interpro:IPR029058|ensemblfungi:YBR177C(gene)|ensemblfungi:YBR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034319"(alcohol O-butanoyltransferase activity)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|reactome:R-SCE-1483191 psi-mi:"MI:0469"(intact) crc64:48CF8D45FC031772 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AkWsG1VUBGxajiAMw0e0mOljZ6s559292 rogid:9arzlcrZmkK0VXN7Zw87dAe1Txc559292 intact-crc:9BEF9FAC06C9D2A9|rigid:0SeTlPtOZWmBoR/3lAI5TwAbyzA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40471 uniprotkb:P38295 intact:EBI-25213|uniprotkb:D6VVG3|ensemblfungi:YIL124W intact:EBI-20890|uniprotkb:D6VQH2|ensemblfungi:YBR177C psi-mi:ayr1_yeast(display_long)|uniprotkb:AYR1(gene name)|psi-mi:AYR1(display_short)|uniprotkb:Acylglycerone-phosphate reductase(gene name synonym)|uniprotkb:1-acyl DHAP reductase(gene name synonym)|uniprotkb:Acyl/alkyl DHAP reductase(gene name synonym)|uniprotkb:GBG1(gene name synonym)|uniprotkb:Triacylglycerol lipase AYR1(gene name synonym)|uniprotkb:YIL124W(locus name) psi-mi:mcfs2_yeast(display_long)|uniprotkb:YBR177C(locus name)|uniprotkb:YBR1239(orf name)|uniprotkb:EHT1(gene name)|psi-mi:EHT1(display_short)|uniprotkb:Alcohol O-acetyltransferase(gene name synonym)|uniprotkb:Ethanol hexanoyl transferase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328056|imex:IM-14275-1285 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001386|refseq:NP_012142.3|mint:P40471|dip:DIP-4614N|ensemblfungi:YIL124W(gene)|ensemblfungi:YIL124W_mRNA(transcript)|go:"GO:0000140"(acylglycerone-phosphate reductase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0102566"(1-acyl dihydroxyacetone phosphate reductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291 refseq:NP_009736.3|sgd:S000000381|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|mint:P38295|interpro:IPR029058|ensemblfungi:YBR177C(gene)|ensemblfungi:YBR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034319"(alcohol O-butanoyltransferase activity)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|reactome:R-SCE-1483191 psi-mi:"MI:0469"(intact) crc64:B614C0E0B1FB0CE0 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WE4RmSXARj683MNUEsYGLis36Xo559292 rogid:9arzlcrZmkK0VXN7Zw87dAe1Txc559292 intact-crc:4474842CD1262D99|rigid:f8vZX1/etzyj6DzXRm2qVu7cPyM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38295 uniprotkb:P54783 intact:EBI-20890|uniprotkb:D6VQH2|ensemblfungi:YBR177C intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:mcfs2_yeast(display_long)|uniprotkb:YBR177C(locus name)|uniprotkb:YBR1239(orf name)|uniprotkb:EHT1(gene name)|psi-mi:EHT1(display_short)|uniprotkb:Alcohol O-acetyltransferase(gene name synonym)|uniprotkb:Ethanol hexanoyl transferase 1(gene name synonym) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328067|imex:IM-14275-1286 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009736.3|sgd:S000000381|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|mint:P38295|interpro:IPR029058|ensemblfungi:YBR177C(gene)|ensemblfungi:YBR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034319"(alcohol O-butanoyltransferase activity)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|reactome:R-SCE-1483191 go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9arzlcrZmkK0VXN7Zw87dAe1Txc559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:D9846FECFFE703F4|rigid:maumHpxnwXcEuJuirx7f7LoGn50 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38295 uniprotkb:Q07804 intact:EBI-20890|uniprotkb:D6VQH2|ensemblfungi:YBR177C intact:EBI-36254|uniprotkb:D6VXZ0|ensemblfungi:YLL012W psi-mi:mcfs2_yeast(display_long)|uniprotkb:YBR177C(locus name)|uniprotkb:YBR1239(orf name)|uniprotkb:EHT1(gene name)|psi-mi:EHT1(display_short)|uniprotkb:Alcohol O-acetyltransferase(gene name synonym)|uniprotkb:Ethanol hexanoyl transferase 1(gene name synonym) psi-mi:yeh1_yeast(display_long)|uniprotkb:Steryl ester hydrolase 1(gene name synonym)|uniprotkb:YEH1(gene name)|psi-mi:YEH1(display_short)|uniprotkb:YLL012W(locus name)|uniprotkb:L1329(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328078|imex:IM-14275-1287 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009736.3|sgd:S000000381|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|mint:P38295|interpro:IPR029058|ensemblfungi:YBR177C(gene)|ensemblfungi:YBR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034319"(alcohol O-butanoyltransferase activity)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|reactome:R-SCE-1483191 refseq:NP_013089.1|sgd:S000003935|mint:Q07804|dip:DIP-4156N|ensemblfungi:YLL012W(gene)|ensemblfungi:YLL012W_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016125"(sterol metabolic process)|interpro:IPR006693(AB-hydrolase associated lipase region)|interpro:IPR029058|reactome:R-SCE-192456|reactome:R-SCE-6809371 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9arzlcrZmkK0VXN7Zw87dAe1Txc559292 rogid:Fv+RBBi6c7i++sW0AISZDXDrlrI559292 intact-crc:0E6BABEBE4D9181C|rigid:Bcx3P4K+IppnCu+RHwQg/EPx+hI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12168 uniprotkb:P38295 intact:EBI-32973|uniprotkb:Q07268|uniprotkb:D6VYD8|ensemblfungi:YLR144C intact:EBI-20890|uniprotkb:D6VQH2|ensemblfungi:YBR177C psi-mi:eng2_yeast(display_long)|uniprotkb:ACF2(gene name)|psi-mi:ACF2(display_short)|uniprotkb:YLR144C(locus name)|uniprotkb:Laminarinase-2(gene name synonym)|uniprotkb:ENG2(gene name synonym)|uniprotkb:PCA1(gene name synonym)|uniprotkb:L3180(orf name) psi-mi:mcfs2_yeast(display_long)|uniprotkb:YBR177C(locus name)|uniprotkb:YBR1239(orf name)|uniprotkb:EHT1(gene name)|psi-mi:EHT1(display_short)|uniprotkb:Alcohol O-acetyltransferase(gene name synonym)|uniprotkb:Ethanol hexanoyl transferase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328089|imex:IM-14275-1288 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013245.1|sgd:S000004134|mint:Q12168|dip:DIP-2889N|ensemblfungi:YLR144C(gene)|ensemblfungi:YLR144C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042973"(glucan endo-1,3-beta-D-glucosidase activity)|go:"GO:0052861"(glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group)|go:"GO:0052862"(glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group)|interpro:IPR005200(Glycoside hydrolase, family 81)|interpro:IPR040451|interpro:IPR040720 refseq:NP_009736.3|sgd:S000000381|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|mint:P38295|interpro:IPR029058|ensemblfungi:YBR177C(gene)|ensemblfungi:YBR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034319"(alcohol O-butanoyltransferase activity)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|reactome:R-SCE-1483191 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8STCUe6Ie2CnTTBMjY8wrld5h44559292 rogid:9arzlcrZmkK0VXN7Zw87dAe1Txc559292 intact-crc:3FF04179D8FF15EF|rigid:8+xBTGXbXsRagibsnvMOgQG3vcg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:P38310 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328100|imex:IM-14275-1289 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) - crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:7021A32A9A46C9E0|rigid:CKJONO0KxowDr1BG6Bs/wolfQ8A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13134 uniprotkb:P38310 intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5 intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328111|imex:IM-14275-1290 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134 refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) crc64:5DCEEDADCF439C78 crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:78790B0D0BB2CF89|rigid:caaPH1O1ywp2rievR0tI/XlSH8o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38310 uniprotkb:P32319 intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W intact:EBI-13123|uniprotkb:D6VPY3|ensemblfungi:YBL017C psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:vps10_yeast(display_long)|uniprotkb:PEP1(gene name)|psi-mi:PEP1(display_short)|uniprotkb:Vacuolar carboxypeptidase sorting receptor VPS10(gene name synonym)|uniprotkb:Carboxypeptidase Y receptor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 1(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 1(gene name synonym)|uniprotkb:Sortilin VPS10(gene name synonym)|uniprotkb:VPS10(gene name synonym)|uniprotkb:VPT1(gene name synonym)|uniprotkb:YBL03.22(orf name)|uniprotkb:YBL0302(orf name)|uniprotkb:YBL017C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328122|imex:IM-14275-1291 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) refseq:NP_009536.1|sgd:S000000113|mint:P32319|dip:DIP-5900N|ensemblfungi:YBL017C(gene)|ensemblfungi:YBL017C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000423"(mitophagy)|go:"GO:0000425"(pexophagy)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048203"(vesicle targeting, trans-Golgi to endosome)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR036278 psi-mi:"MI:0469"(intact) crc64:7B4E620ABC39A053 crc64:C778A0400612ECF4 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 rogid:dYYsekAaDw4SzmEUSe5tYb5a43M559292 intact-crc:84E20F91622279A4|rigid:gCQAvUMnEipwS5q1FFoHczmALqw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38310 uniprotkb:P32386 intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W intact:EBI-21511|uniprotkb:Q07882|uniprotkb:D6VXW0|ensemblfungi:YLL048C psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:ybt1_yeast(display_long)|uniprotkb:YBT1(gene name)|psi-mi:YBT1(display_short)|uniprotkb:BAT1(gene name synonym)|uniprotkb:YLL048C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328133|imex:IM-14275-1292 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) refseq:NP_013052.1|sgd:S000003971|mint:P32386|dip:DIP-6474N|ensemblfungi:YLL048C(gene)|ensemblfungi:YLL048C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006816"(calcium ion transport)|go:"GO:0015718"(monocarboxylic acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033285"(ATPase-coupled monocarboxylic acid transmembrane transporter activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 psi-mi:"MI:0469"(intact) crc64:7B4E620ABC39A053 crc64:E71D3D57A3013C38 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 rogid:b0Cz526nha/7DJPmG1uADmBnNPA559292 intact-crc:FF8B0FAB9AD4C720|rigid:G/mZYmVVMbZihhNYW7Iphe3izqc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38310 uniprotkb:P32465 intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328144|imex:IM-14275-1293 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N psi-mi:"MI:0469"(intact) crc64:7B4E620ABC39A053 - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 intact-crc:8C492D066B058419|rigid:ZJDVdKTLpX9GwuVhtl7OLbfiYeg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32610 uniprotkb:P38310 intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328155|imex:IM-14275-1294 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610 refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) crc64:FDE93E1FAF0AEC5B crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:18B0EAB034816B69|rigid:cxwcv17P9e1J4c7JR0cMXfueMUM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32660 uniprotkb:P38310 intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328166|imex:IM-14275-1295 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) crc64:3CC3FBA8ADDE8960 crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:A4953EA02A0307A0|rigid:pEk7KW65OKmpxDV96h3VEgQBVkI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32798 uniprotkb:P38310 intact:EBI-5006|uniprotkb:D6W314|ensemblfungi:YOR316C intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:cot1_yeast(display_long)|uniprotkb:COT1(gene name)|psi-mi:COT1(display_short)|uniprotkb:O6131(orf name)|uniprotkb:YOR316C(locus name) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328177|imex:IM-14275-1296 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005843|refseq:NP_014961.3|dip:DIP-7554N|mint:P32798|ensemblfungi:YOR316C(gene)|ensemblfungi:YOR316C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006824"(cobalt ion transport)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0015087"(cobalt ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410 refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) - crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HEIg6lhS698E9H3BJeESYAipNwA559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:C5539E35FB12D8C2|rigid:K1zSCFzWWm7XbjHjjZtmjtnbct8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34110 uniprotkb:P38310 intact:EBI-20415|uniprotkb:D6VW33|ensemblfungi:YJL154C intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:vps35_yeast(display_long)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:Vacuolar protein-targeting protein 7(gene name synonym)|uniprotkb:VPT7(gene name synonym)|uniprotkb:J0580(orf name)|uniprotkb:YJL154C(locus name) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328188|imex:IM-14275-1297 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012381.1|sgd:S000003690|ensemblfungi:YJL154C(gene)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1904377"(positive regulation of protein localization to cell periphery)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR042491|reactome:R-SCE-3238698|ensemblfungi:YJL154C_mRNA(transcript)|dip:DIP-1743N|mint:P34110 refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) crc64:DE1BC57B9DFB606E crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5KBi/lSF+BsMyg9ulP9eLCp2xCc559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:BC3AAB563CBE428A|rigid:IPliaNntc51R6bLkhpxrJ082QTI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38310 uniprotkb:P38310 intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328199|imex:IM-14275-1298 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) crc64:7B4E620ABC39A053 crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:282950422AFA3BE9|rigid:HSeD7tDZYNbGEOrp/r1ez4UO3fE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38310 uniprotkb:P38929 intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328210|imex:IM-14275-1299 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 psi-mi:"MI:0469"(intact) crc64:7B4E620ABC39A053 crc64:5BD9ECFF8508F396 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 intact-crc:AD908BF205BFEFB2|rigid:Xv02bus7//Y0+bfDswvdZMDkf0o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39111 uniprotkb:P38310 intact:EBI-20272|uniprotkb:D6VUF5|ensemblfungi:YGR020C intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:vatf_yeast(display_long)|uniprotkb:VMA7(gene name)|psi-mi:VMA7(display_short)|uniprotkb:YGR020C(locus name)|uniprotkb:Vacuolar proton pump subunit F(gene name synonym)|uniprotkb:V-ATPase 14 kDa subunit(gene name synonym) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328221|imex:IM-14275-1300 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011534.1|sgd:S000003252|ensemblfungi:YGR020C(gene)|ensemblfungi:YGR020C_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016020"(membrane)|go:"GO:0042625"(ATPase-coupled ion transmembrane transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005772(ATPase, V1 complex, subunit F, eukaryotic)|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|interpro:IPR036906|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4IX9|rcsb pdb:4RND|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2077N|mint:P39111 refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) crc64:D21EC0980EB99DFF crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VtthQl2jj9fpjv3psX0YUNbIAKU559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:D68DB549A0490870|rigid:dWVJdZvtBSTn52FafIJ12aVr8bM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38310 uniprotkb:P39968 intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328232|imex:IM-14275-1301 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N psi-mi:"MI:0469"(intact) crc64:7B4E620ABC39A053 crc64:B2E75774B47E5933 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292 intact-crc:D8E835A701D746BA|rigid:Ps6oyw0BqQOFWQ4fUR8hNN7zP2I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41807 uniprotkb:P38310 intact:EBI-20281|uniprotkb:D6W446|ensemblfungi:YPR036W intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:vath_yeast(display_long)|uniprotkb:YP3085.02(orf name)|uniprotkb:VMA13(gene name)|psi-mi:VMA13(display_short)|uniprotkb:CLS11(gene name synonym)|uniprotkb:YPR036W(locus name)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 54 kDa subunit(gene name synonym) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328243|imex:IM-14275-1302 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015361.1|sgd:S000006240|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|rcsb pdb:1HO8|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YPR036W(gene)|ensemblfungi:YPR036W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|dip:DIP-6640N|mint:P41807 refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) crc64:54131FF9C2C87594 crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kEXWvOsnTk0WdgGOny+mufz4lTo559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:1BEB22AC5E34335F|rigid:Hp5o1ThKTuKfPv4yYxM8vZFL1Uo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43561 uniprotkb:P38310 intact:EBI-6891|uniprotkb:D6VTI9|ensemblfungi:YFL041W intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:fet5_yeast(display_long)|uniprotkb:YFL041W(locus name)|uniprotkb:FET5(gene name)|psi-mi:FET5(display_short) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328254|imex:IM-14275-1303 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116612.1|sgd:S000001853|mint:P43561|dip:DIP-6774N|ensemblfungi:YFL041W(gene)|ensemblfungi:YFL041W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006826"(iron ion transport)|go:"GO:0010106"(cellular response to iron ion starvation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0033215"(reductive iron assimilation)|go:"GO:0034755"(iron ion transmembrane transport)|interpro:IPR001117(Multicopper oxidase, type 1)|interpro:IPR002355(Multicopper oxidase, copper-binding site)|interpro:IPR008972(Cupredoxin)|interpro:IPR011706(Multicopper oxidase, type 2)|interpro:IPR011707(Multicopper oxidase, type 3)|interpro:IPR033138|interpro:IPR044130 refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) - crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Po/KJNFIGJj4hdCBkOxRkFEiuqI559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:8A5CF0685A481EAC|rigid:4xx9l1U0dc8Y2VImWKX+0a4qWis false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38310 uniprotkb:P46989 intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328265|imex:IM-14275-1304 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:7B4E620ABC39A053 - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 intact-crc:FC260427B92771FD|rigid:tt7tzjzJe6q2wzbz1cgrczU/cCA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53290 uniprotkb:P38310 intact:EBI-7962|uniprotkb:D6VUU7|ensemblfungi:YGR163W intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:gtr2_yeast(display_long)|uniprotkb:YGR163W(locus name)|uniprotkb:GTR2(gene name)|psi-mi:GTR2(display_short) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328276|imex:IM-14275-1305 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003395|refseq:NP_011679.3|mint:P53290|dip:DIP-4521N|ensemblfungi:YGR163W(gene)|ensemblfungi:YGR163W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000785"(chromatin)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039400|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) crc64:0A0D16C81F73184D crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+b9bPvzin/YUc5fOZZVCcFu/GEM559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:E4DF3D58D221DD7A|rigid:KIzp1QOygtVJms//F6o19cn5UcM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38310 uniprotkb:Q02205 intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W intact:EBI-27062|uniprotkb:D6VX73|ensemblfungi:YKR007W psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:meh1_yeast(display_long)|uniprotkb:GSE complex subunit 2(gene name synonym)|uniprotkb:EGO complex subunit 1(gene name synonym)|uniprotkb:YKR007W(locus name)|uniprotkb:YK106(orf name)|uniprotkb:MEH1(gene name)|psi-mi:MEH1(display_short)|uniprotkb:EGO1(gene name synonym)|uniprotkb:GSE2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328287|imex:IM-14275-1306 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) sgd:S000001715|refseq:NP_012932.1|mint:Q02205|dip:DIP-1922N|ensemblfungi:YKR007W(gene)|ensemblfungi:YKR007W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0005829"(cytosol)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007040"(lysosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR028209|rcsb pdb:4XPM|rcsb pdb:6JWP psi-mi:"MI:0469"(intact) crc64:7B4E620ABC39A053 crc64:995DD1E68331D050 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 rogid:73a6e5W5wQixGg2aGXDo4A6NR2s559292 intact-crc:145F9740BE071441|rigid:JoUQZesx1jsecqDqS0vipPRYt6E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03730 uniprotkb:P38310 intact:EBI-27739|uniprotkb:Q6B2K7|uniprotkb:D6VZF6|ensemblfungi:YML018C intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:ymb8_yeast(display_long)|uniprotkb:YML018C(locus name) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328298|imex:IM-14275-1307 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004480|refseq:NP_013694.1|dip:DIP-4953N|mint:Q03730|ensemblfungi:YML018C(gene)|ensemblfungi:YML018C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane) refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) crc64:DEC5C3EEF293F5ED crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4WxEFdhqbP7pcRcTLeFHljCVQ34559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:1B490BE1F8F9BBA4|rigid:2ZuDeJLg+kUrbnjZIR7rkdLh/vc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03860 uniprotkb:P38310 intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328309|imex:IM-14275-1308 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) crc64:395F700FBB14C569 crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:495435212E8848EC|rigid:/3/dDA2hKj5SWQrgd3P74EwCMC4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38310 uniprotkb:Q06328 intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W intact:EBI-37173|uniprotkb:D6VSY2|ensemblfungi:YDR352W psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:ypq2_yeast(display_long)|uniprotkb:YPQ2(gene name)|psi-mi:YPQ2(display_short)|uniprotkb:PQ-loop repeat-containing protein 2(gene name synonym)|uniprotkb:YDR352W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328320|imex:IM-14275-1309 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) refseq:NP_010639.1|sgd:S000002760|interpro:IPR006603(Cystinosin/ERS1p repeat)|mint:Q06328|ensemblfungi:YDR352W(gene)|ensemblfungi:YDR352W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0015174"(basic amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034488"(basic amino acid transmembrane export from vacuole)|go:"GO:0071627"(integral component of fungal-type vacuolar membrane)|reactome:R-SCE-5223345 psi-mi:"MI:0469"(intact) crc64:7B4E620ABC39A053 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 rogid:tLoew2CtLfiBlJVBfq1TPSEozJk559292 intact-crc:FBD9811E80C1943E|rigid:DuM/cYQVdSKS3JYga//tRLq2WT0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38310 uniprotkb:Q06815 intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W intact:EBI-33784|uniprotkb:D6W481|ensemblfungi:YPR079W psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:mrl1_yeast(display_long)|uniprotkb:YPR079W(locus name)|uniprotkb:MRL1(gene name)|psi-mi:MRL1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328331|imex:IM-14275-1310 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) refseq:NP_015404.1|sgd:S000006283|mint:Q06815|dip:DIP-2873N|ensemblfungi:YPR079W(gene)|ensemblfungi:YPR079W_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007034"(vacuolar transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR036607|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:7B4E620ABC39A053 - figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 rogid:PFMxRfVBupoO0p3pb+BB5H2fidg559292 intact-crc:AFD7FD9F32C31CC2|rigid:WECuX2UQDKjcbTMr90in43LbSwY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12407 uniprotkb:P38310 intact:EBI-33162|uniprotkb:D6VRF5|ensemblfungi:YDL199C intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:yd199_yeast(display_long)|uniprotkb:D1209(orf name)|uniprotkb:YDL199C(locus name) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328342|imex:IM-14275-1311 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010082.1|sgd:S000002358|mint:Q12407|dip:DIP-8956N|ensemblfungi:YDL199C(gene)|ensemblfungi:YDL199C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0008643"(carbohydrate transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) - crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:s39vivUjIZIzcTO4OLM/PbrCjvM559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:19269BDB91327FF7|rigid:tKMHgBex0YryH4HPR0B03Ft/EAA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07286 uniprotkb:P38314 intact:EBI-7852|uniprotkb:D6VQN9|ensemblfungi:YBR243C intact:EBI-20977|uniprotkb:D6VQL0|ensemblfungi:YBR214W psi-mi:gpt_yeast(display_long)|uniprotkb:TUR1(gene name synonym)|uniprotkb:YBR1628(orf name)|uniprotkb:YBR243C(locus name)|uniprotkb:ALG7(gene name)|psi-mi:ALG7(display_short)|uniprotkb:N-acetylglucosamine-1-phosphate transferase(gene name synonym)|uniprotkb:GlcNAc-1-P transferase(gene name synonym)|uniprotkb:Tunicamycin resistance protein 1(gene name synonym) psi-mi:sds24_yeast(display_long)|uniprotkb:YBR1501(orf name)|uniprotkb:YBR214W(locus name)|uniprotkb:SDS24(gene name)|psi-mi:SDS24(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328353|imex:IM-14275-1312 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000447|refseq:NP_009802.3|dip:DIP-5364N|mint:P07286|ensemblfungi:YBR243C(gene)|ensemblfungi:YBR243C_mRNA(transcript)|go:"GO:0003975"(UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006489"(dolichyl diphosphate biosynthetic process)|go:"GO:0008963"(phospho-N-acetylmuramoyl-pentapeptide-transferase activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0043541"(UDP-N-acetylglucosamine transferase complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR000715(Glycosyl transferase, family 4)|interpro:IPR033895|reactome:R-SCE-446193 refseq:NP_009773.1|sgd:S000000418|mint:P38314|dip:DIP-2542N|ensemblfungi:YBR214W(gene)|ensemblfungi:YBR214W_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR016711(Sds23) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nwAb0WMTgVU4LoAGHFxOjCYe1ok559292 rogid:Z5MI41Cj7bTGslibR8qbEMdyPek559292 intact-crc:E54313E7AE01154F|rigid:vZmXP6gvh/NxIMgQT+NaSfy7P84 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38314 uniprotkb:P38634 intact:EBI-20977|uniprotkb:D6VQL0|ensemblfungi:YBR214W intact:EBI-17127|ensemblfungi:YLR079W|uniprotkb:D6VY79 psi-mi:sds24_yeast(display_long)|uniprotkb:YBR1501(orf name)|uniprotkb:YBR214W(locus name)|uniprotkb:SDS24(gene name)|psi-mi:SDS24(display_short) psi-mi:sic1_yeast(display_long)|uniprotkb:SIC1(gene name)|psi-mi:SIC1(display_short)|uniprotkb:SDB25(gene name synonym)|uniprotkb:YLR079W(locus name)|uniprotkb:L9449.8(orf name)|uniprotkb:CDK inhibitor p40(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328364|imex:IM-14275-1313 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009773.1|sgd:S000000418|mint:P38314|dip:DIP-2542N|ensemblfungi:YBR214W(gene)|ensemblfungi:YBR214W_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR016711(Sds23) ensemblfungi:YLR079W(gene)|ensemblfungi:YLR079W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016242"(negative regulation of macroautophagy)|rcsb pdb:3V7D|rcsb pdb:6G86|refseq:NP_013180.1|sgd:S000004069|dip:DIP-6817N|mint:P38634 psi-mi:"MI:0469"(intact) - crc64:7913636340678F78 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Z5MI41Cj7bTGslibR8qbEMdyPek559292 rogid:qU8ivBCZHvG4VmXDxv52yc08Hwc559292 intact-crc:52662F832338792B|rigid:Pd79ShKRdwETsrKBtSrnG4AbXA0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43612 uniprotkb:P38314 intact:EBI-16370|ensemblfungi:YFR040W|uniprotkb:Q96VG4|uniprotkb:D6VTS3 intact:EBI-20977|uniprotkb:D6VQL0|ensemblfungi:YBR214W psi-mi:sa155_yeast(display_long)|uniprotkb:SAP155(gene name)|psi-mi:SAP155(display_short)|uniprotkb:YFR040W(locus name) psi-mi:sds24_yeast(display_long)|uniprotkb:YBR1501(orf name)|uniprotkb:YBR214W(locus name)|uniprotkb:SDS24(gene name)|psi-mi:SDS24(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328375|imex:IM-14275-1314 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YFR040W(gene)|ensemblfungi:YFR040W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|reactome:R-SCE-204005|refseq:NP_116698.3|sgd:S000001936|dip:DIP-5852N|mint:P43612 refseq:NP_009773.1|sgd:S000000418|mint:P38314|dip:DIP-2542N|ensemblfungi:YBR214W(gene)|ensemblfungi:YBR214W_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR016711(Sds23) psi-mi:"MI:0469"(intact) crc64:50CDC17130333022 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:OX+DqsaQW7F5rHzNB2R69wYu6YE559292 rogid:Z5MI41Cj7bTGslibR8qbEMdyPek559292 intact-crc:F9FA22EA2E213EDE|rigid:CT2ih9Xba4Lfl+VKWXj3ZVHri4Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53251 uniprotkb:P38333 intact:EBI-23221|ensemblfungi:YGR081C intact:EBI-6482|uniprotkb:D6VQP3|ensemblfungi:YBR247C psi-mi:slx9_yeast(display_long)|uniprotkb:YGR081C(locus name)|uniprotkb:SLX9(gene name)|psi-mi:SLX9(display_short) psi-mi:enp1_yeast(display_long)|uniprotkb:ENP1(gene name)|psi-mi:ENP1(display_short)|uniprotkb:MEG1(gene name synonym)|uniprotkb:YBR247C(locus name)|uniprotkb:YBR1635(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328386|imex:IM-14275-1315 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003313|refseq:NP_011595.3|dip:DIP-4723N|mint:P53251|ensemblfungi:YGR081C(gene)|ensemblfungi:YGR081C_mRNA(transcript)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0051880"(G-quadruplex DNA binding)|interpro:IPR028160 refseq:NP_009806.3|sgd:S000000451|mint:P38333|dip:DIP-6612N|ensemblfungi:YBR247C(gene)|ensemblfungi:YBR247C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|interpro:IPR007955(Bystin)|rcsb pdb:5WLC|rcsb pdb:5WWO|rcsb pdb:5WYJ|rcsb pdb:6EML|rcsb pdb:6FAI|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6RBD|rcsb pdb:6Y7C|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) - crc64:399A415131294637 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Kx6WAtNZyIgHtsPoSOLxBCcnROA559292 rogid:hRWEGOAGLPtihuRsJqQDpZyNtcE559292 intact-crc:39271A06909DAB53|rigid:75f5z9BtOgRuRXGekmBo1XXmtRI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:P38342 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-21124|uniprotkb:D6VQR2|ensemblfungi:YBR265W psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:tsc10_yeast(display_long)|uniprotkb:YBR265W(locus name)|uniprotkb:YBR1734(orf name)|uniprotkb:TSC10(gene name)|psi-mi:TSC10(display_short)|uniprotkb:3-dehydrosphinganine reductase(gene name synonym)|uniprotkb:KDS reductase(gene name synonym)|uniprotkb:Temperature-sensitive CSG2 suppressor protein 10(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328397|imex:IM-14275-1316 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD refseq:NP_009824.2|sgd:S000000469|mint:P38342|dip:DIP-4781N|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0047560"(3-dehydrosphinganine reductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|reactome:R-SCE-1660661|ensemblfungi:YBR265W(gene)|ensemblfungi:YBR265W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006666"(3-keto-sphinganine metabolic process)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) crc64:DBA26AF5B769C02A crc64:C5F251B4099E6242 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:P1vN8UPwJPpbq+jxlW/9hPaIkFQ559292 intact-crc:5148DA62478D1DCD|rigid:OhyBaCa9Hv9oNwTjI1VH9rnlBdU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38344 uniprotkb:P25293 intact:EBI-21136|uniprotkb:D6VQR3|ensemblfungi:YBR267W intact:EBI-11850|uniprotkb:P87196|ensemblfungi:YKR048C|uniprotkb:D6VXA9 psi-mi:rei1_yeast(display_long)|uniprotkb:REI1(gene name)|psi-mi:REI1(display_short)|uniprotkb:Required for isotropic bud growth protein 1(gene name synonym)|uniprotkb:pre-60S factor REI1(gene name synonym)|uniprotkb:YBR1736(orf name)|uniprotkb:YBR267W(locus name) psi-mi:nap1_yeast(display_long)|uniprotkb:NAP1(gene name)|psi-mi:NAP1(display_short)|uniprotkb:YKR048C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328408|imex:IM-14275-1317 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009825.4|sgd:S000000471|mint:P38344|dip:DIP-6347N|rcsb pdb:6RZZ|rcsb pdb:5APN|ensemblfungi:YBR267W(gene)|ensemblfungi:YBR267W_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR040025|interpro:IPR041661 ensemblfungi:YKR048C(gene)|ensemblfungi:YKR048C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032153"(cell division site)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0098841"(protein localization to cell division site after cytokinesis)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|rcsb pdb:2AYU|rcsb pdb:2Z2R|rcsb pdb:5G2E|go:"GO:0032174"(cellular bud neck septin collar)|refseq:NP_012974.1|sgd:S000001756|dip:DIP-1380N|mint:P25293 psi-mi:"MI:0469"(intact) crc64:D01AA8FFDF4A0BAC crc64:C0F97FBA1B9EEA83 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YxMyWWxJUH2Pk41X+98x8jcnqhc559292 rogid:MBxVJ0JmlEg5coqnQd6uoSX2uC0559292 intact-crc:5F856DCA9E91B9C9|rigid:YQV882p/vxjs34Gq1MZaqZr//l0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38344 uniprotkb:P38615 intact:EBI-21136|uniprotkb:D6VQR3|ensemblfungi:YBR267W intact:EBI-10642|uniprotkb:Q6Q5K4|ensemblfungi:YMR139W|uniprotkb:D6VZW2 psi-mi:rei1_yeast(display_long)|uniprotkb:REI1(gene name)|psi-mi:REI1(display_short)|uniprotkb:Required for isotropic bud growth protein 1(gene name synonym)|uniprotkb:pre-60S factor REI1(gene name synonym)|uniprotkb:YBR1736(orf name)|uniprotkb:YBR267W(locus name) psi-mi:rim11_yeast(display_long)|uniprotkb:RIM11(gene name)|psi-mi:RIM11(display_short)|uniprotkb:GSK3(gene name synonym)|uniprotkb:MDS1(gene name synonym)|uniprotkb:YMR139W(locus name)|uniprotkb:YM9375.08(orf name)|uniprotkb:Regulator of IME2 protein 11(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328419|imex:IM-14275-1318 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009825.4|sgd:S000000471|mint:P38344|dip:DIP-6347N|rcsb pdb:6RZZ|rcsb pdb:5APN|ensemblfungi:YBR267W(gene)|ensemblfungi:YBR267W_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR040025|interpro:IPR041661 refseq:NP_013859.1|sgd:S000004747|ensemblfungi:YMR139W(gene)|ensemblfungi:YMR139W_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0030437"(ascospore formation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|reactome:R-SCE-3371453|mint:P38615|dip:DIP-1566N psi-mi:"MI:0469"(intact) crc64:D01AA8FFDF4A0BAC crc64:59D92C9D42408E97 figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YxMyWWxJUH2Pk41X+98x8jcnqhc559292 rogid:HR/odTTwzM907syfBEfaJny7t5Q559292 intact-crc:4D8224635CCF503A|rigid:63Wg14ulXxhH0TaG/C4nUV2XAII false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38344 uniprotkb:P53145 intact:EBI-21136|uniprotkb:D6VQR3|ensemblfungi:YBR267W intact:EBI-23885|uniprotkb:D6VU46|ensemblfungi:YGL099W psi-mi:rei1_yeast(display_long)|uniprotkb:REI1(gene name)|psi-mi:REI1(display_short)|uniprotkb:Required for isotropic bud growth protein 1(gene name synonym)|uniprotkb:pre-60S factor REI1(gene name synonym)|uniprotkb:YBR1736(orf name)|uniprotkb:YBR267W(locus name) psi-mi:lsg1_yeast(display_long)|uniprotkb:LSG1(gene name)|psi-mi:LSG1(display_short)|uniprotkb:YGL099W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328430|imex:IM-14275-1319 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009825.4|sgd:S000000471|mint:P38344|dip:DIP-6347N|rcsb pdb:6RZZ|rcsb pdb:5APN|ensemblfungi:YBR267W(gene)|ensemblfungi:YBR267W_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR040025|interpro:IPR041661 sgd:S000003067|refseq:NP_011416.3|dip:DIP-6659N|mint:P53145|ensemblfungi:YGL099W(gene)|ensemblfungi:YGL099W_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0043332"(mating projection tip)|interpro:IPR006073(GTP1/OBG)|interpro:IPR027417|interpro:IPR030378|interpro:IPR043358|rcsb pdb:5T62|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6QIK|rcsb pdb:6QTZ|rcsb pdb:6RI5|rcsb pdb:6RZZ|rcsb pdb:6S05 psi-mi:"MI:0469"(intact) crc64:D01AA8FFDF4A0BAC crc64:15FD76541A2E8410 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YxMyWWxJUH2Pk41X+98x8jcnqhc559292 rogid:9mANWO3rTsE/zCUr9GL6WxIexMU559292 intact-crc:DC486F41115DED45|rigid:zIjuyV+Cj+PZHIxsMCnnJEKBylg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38353 uniprotkb:P38264 intact:EBI-18175|uniprotkb:D6VQS8|ensemblfungi:YBR283C intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 psi-mi:ssh1_yeast(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:Ssh1 complex subunit alpha(gene name synonym)|uniprotkb:Ssh1 complex subunit SSH1(gene name synonym)|uniprotkb:YBR2020(orf name)|uniprotkb:YBR283C(locus name) psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328441|imex:IM-14275-1320 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009842.1|sgd:S000000487|ensemblfungi:YBR283C(gene)|ensemblfungi:YBR283C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:2WW9|rcsb pdb:2WWA|dip:DIP-4962N|mint:P38353 refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N psi-mi:"MI:0469"(intact) crc64:48267EEA3E0191BD - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:76wvZIdv7W5BQn6wI+sHOGQAyuc559292 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 intact-crc:BA95322E28CC8C5B|rigid:++pWfRv5ofY9EKjvcW+OpFe9o3k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38353 uniprotkb:P38985 intact:EBI-18175|uniprotkb:D6VQS8|ensemblfungi:YBR283C intact:EBI-17977|uniprotkb:D6VRQ6|ensemblfungi:YDL092W psi-mi:ssh1_yeast(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:Ssh1 complex subunit alpha(gene name synonym)|uniprotkb:Ssh1 complex subunit SSH1(gene name synonym)|uniprotkb:YBR2020(orf name)|uniprotkb:YBR283C(locus name) psi-mi:srp14_yeast(display_long)|uniprotkb:SRP14(gene name)|psi-mi:SRP14(display_short)|uniprotkb:YDL092W(locus name)|uniprotkb:D2404(orf name)|uniprotkb:Signal recognition particle 14 kDa protein homolog(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328452|imex:IM-14275-1321 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009842.1|sgd:S000000487|ensemblfungi:YBR283C(gene)|ensemblfungi:YBR283C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:2WW9|rcsb pdb:2WWA|dip:DIP-4962N|mint:P38353 refseq:NP_010191.1|sgd:S000002250|ensemblfungi:YDL092W(gene)|ensemblfungi:YDL092W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR003210(Signal recognition particle, SRP14 subunit)|interpro:IPR009018(Signal recognition particle, SRP9/SRP14 subunit)|reactome:R-SCE-1799339|reactome:R-SCE-6798695|dip:DIP-4864N|mint:P38985 psi-mi:"MI:0469"(intact) crc64:48267EEA3E0191BD - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:76wvZIdv7W5BQn6wI+sHOGQAyuc559292 rogid:I9myDFdKPRnrKsHBhWBxI/Em7EQ559292 intact-crc:E87A441915D760AF|rigid:pj2srdI/Mo3BBwDlz9HRIQ9oeso false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53337 uniprotkb:P38353 intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C intact:EBI-18175|uniprotkb:D6VQS8|ensemblfungi:YBR283C psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:ssh1_yeast(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:Ssh1 complex subunit alpha(gene name synonym)|uniprotkb:Ssh1 complex subunit SSH1(gene name synonym)|uniprotkb:YBR2020(orf name)|uniprotkb:YBR283C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328463|imex:IM-14275-1322 author score:99.34 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 refseq:NP_009842.1|sgd:S000000487|ensemblfungi:YBR283C(gene)|ensemblfungi:YBR283C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:2WW9|rcsb pdb:2WWA|dip:DIP-4962N|mint:P38353 psi-mi:"MI:0469"(intact) - crc64:48267EEA3E0191BD figure legend:tables S3 and S4|author-confidence:99.34|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 rogid:76wvZIdv7W5BQn6wI+sHOGQAyuc559292 intact-crc:23612B8188D167C9|rigid:Wvv9KqCIgInWgb3x6EBwKQhAHds false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38353 uniprotkb:P54837 intact:EBI-18175|uniprotkb:D6VQS8|ensemblfungi:YBR283C intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:ssh1_yeast(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:Ssh1 complex subunit alpha(gene name synonym)|uniprotkb:Ssh1 complex subunit SSH1(gene name synonym)|uniprotkb:YBR2020(orf name)|uniprotkb:YBR283C(locus name) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328474|imex:IM-14275-1323 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009842.1|sgd:S000000487|ensemblfungi:YBR283C(gene)|ensemblfungi:YBR283C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:2WW9|rcsb pdb:2WWA|dip:DIP-4962N|mint:P38353 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:48267EEA3E0191BD - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:76wvZIdv7W5BQn6wI+sHOGQAyuc559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:862242CCE3BBD48E|rigid:duz489Hu82k6uWnZWKivEJLnIKA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:P38353 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-18175|uniprotkb:D6VQS8|ensemblfungi:YBR283C psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:ssh1_yeast(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:Ssh1 complex subunit alpha(gene name synonym)|uniprotkb:Ssh1 complex subunit SSH1(gene name synonym)|uniprotkb:YBR2020(orf name)|uniprotkb:YBR283C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328485|imex:IM-14275-1324 author score:93.51 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_009842.1|sgd:S000000487|ensemblfungi:YBR283C(gene)|ensemblfungi:YBR283C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:2WW9|rcsb pdb:2WWA|dip:DIP-4962N|mint:P38353 psi-mi:"MI:0469"(intact) - crc64:48267EEA3E0191BD figure legend:tables S3 and S4|author-confidence:93.51|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:76wvZIdv7W5BQn6wI+sHOGQAyuc559292 intact-crc:9CBAE194474E2338|rigid:DAOUFkRyvCP2XtNd8TjpQDpuTxQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38353 uniprotkb:Q06144 intact:EBI-18175|uniprotkb:D6VQS8|ensemblfungi:YBR283C intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:ssh1_yeast(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:Ssh1 complex subunit alpha(gene name synonym)|uniprotkb:Ssh1 complex subunit SSH1(gene name synonym)|uniprotkb:YBR2020(orf name)|uniprotkb:YBR283C(locus name) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328496|imex:IM-14275-1325 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009842.1|sgd:S000000487|ensemblfungi:YBR283C(gene)|ensemblfungi:YBR283C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:2WW9|rcsb pdb:2WWA|dip:DIP-4962N|mint:P38353 refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) crc64:48267EEA3E0191BD crc64:2F474503CAB7C195 figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:76wvZIdv7W5BQn6wI+sHOGQAyuc559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 intact-crc:DF12D852277D2340|rigid:jNsUj2U5U/yPqlW2oLa7HGePKc4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38426 uniprotkb:P38426 intact:EBI-19448|uniprotkb:D6W087|uniprotkb:Q6B1W2|ensemblfungi:YMR261C intact:EBI-19448|uniprotkb:D6W087|uniprotkb:Q6B1W2|ensemblfungi:YMR261C psi-mi:tps3_yeast(display_long)|uniprotkb:TPS3(gene name)|psi-mi:TPS3(display_short)|uniprotkb:YMR261C(locus name)|uniprotkb:YM8156.03C(orf name)|uniprotkb:Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 115 kDa subunit(gene name synonym) psi-mi:tps3_yeast(display_long)|uniprotkb:TPS3(gene name)|psi-mi:TPS3(display_short)|uniprotkb:YMR261C(locus name)|uniprotkb:YM8156.03C(orf name)|uniprotkb:Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 115 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328507|imex:IM-14275-1326 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013988.1|sgd:S000004874|ensemblfungi:YMR261C(gene)|ensemblfungi:YMR261C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005946"("alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)")|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR001830(Glycosyl transferase, family 20)|interpro:IPR003337(Trehalose-phosphatase)|interpro:IPR036412|dip:DIP-891N|mint:P38426 refseq:NP_013988.1|sgd:S000004874|ensemblfungi:YMR261C(gene)|ensemblfungi:YMR261C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005946"("alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)")|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR001830(Glycosyl transferase, family 20)|interpro:IPR003337(Trehalose-phosphatase)|interpro:IPR036412|dip:DIP-891N|mint:P38426 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aY+Gu2+xxYxfe40pjJ1KTaYbDxM559292 rogid:aY+Gu2+xxYxfe40pjJ1KTaYbDxM559292 intact-crc:59C618BF2F92F274|rigid:mR7E0oiSYRyAGF2jNVHG6xTn8y8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38555 uniprotkb:P39958 intact:EBI-29379|uniprotkb:D3DLT0|ensemblfungi:YER031C intact:EBI-7517|uniprotkb:D3DM41|ensemblfungi:YER136W psi-mi:ypt31_yeast(display_long)|uniprotkb:Rab GTPase YPT31(gene name synonym)|uniprotkb:YPT31(gene name)|psi-mi:YPT31(display_short)|uniprotkb:YPT8(gene name synonym)|uniprotkb:YER031C(locus name) psi-mi:gdi1_yeast(display_long)|uniprotkb:YER136W(locus name)|uniprotkb:GDI1(gene name)|psi-mi:GDI1(display_short)|uniprotkb:SEC19(gene name synonym)|uniprotkb:Secretory pathway GDP dissociation inhibitor(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328518|imex:IM-14275-1327 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010948.1|sgd:S000000833|dip:DIP-2022N|mint:P38555|ensemblfungi:YER031C(gene)|ensemblfungi:YER031C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0055037"(recycling endosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:3CPJ|reactome:R-SCE-8873719 refseq:NP_011062.1|sgd:S000000938|mint:P39958|dip:DIP-785N|ensemblfungi:YER136W(gene)|ensemblfungi:YER136W_mRNA(transcript)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|rcsb pdb:1UKV|rcsb pdb:2BCG|rcsb pdb:3CPH|rcsb pdb:3CPI|rcsb pdb:3CPJ|reactome:R-SCE-6798695|reactome:R-SCE-8876198 psi-mi:"MI:0469"(intact) crc64:EC274E5873138D78 crc64:48CF8D45FC031772 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:z5YqRrgMniz5YCUrviuNEt5mZMo559292 rogid:AkWsG1VUBGxajiAMw0e0mOljZ6s559292 intact-crc:35EFB8AC31C8CA66|rigid:1/SYpZmw4nR+kDMfN0fCcdRXyyo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38555 uniprotkb:P54783 intact:EBI-29379|uniprotkb:D3DLT0|ensemblfungi:YER031C intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:ypt31_yeast(display_long)|uniprotkb:Rab GTPase YPT31(gene name synonym)|uniprotkb:YPT31(gene name)|psi-mi:YPT31(display_short)|uniprotkb:YPT8(gene name synonym)|uniprotkb:YER031C(locus name) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328529|imex:IM-14275-1328 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010948.1|sgd:S000000833|dip:DIP-2022N|mint:P38555|ensemblfungi:YER031C(gene)|ensemblfungi:YER031C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0055037"(recycling endosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:3CPJ|reactome:R-SCE-8873719 go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) crc64:EC274E5873138D78 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:z5YqRrgMniz5YCUrviuNEt5mZMo559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:778448ECC8E61B3B|rigid:iyMaUlJvIrKq/ptK+o4SnuhGgTY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:P38604 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-6572|uniprotkb:Q92327|uniprotkb:D3DL21|ensemblfungi:YHR072W psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:erg7_yeast(display_long)|uniprotkb:Oxidosqualene--lanosterol cyclase(gene name synonym)|uniprotkb:2,3-epoxysqualene--lanosterol cyclase(gene name synonym)|uniprotkb:YHR072W(locus name)|uniprotkb:ERG7(gene name)|psi-mi:ERG7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328540|imex:IM-14275-1329 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD refseq:NP_011939.2|sgd:S000001114|mint:P38604|dip:DIP-8319N|ensemblfungi:YHR072W(gene)|ensemblfungi:YHR072W_mRNA(transcript)|go:"GO:0000250"(lanosterol synthase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016104"(triterpenoid biosynthetic process)|go:"GO:0042300"(beta-amyrin synthase activity)|interpro:IPR002365(Terpene synthase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR018333|interpro:IPR032696|interpro:IPR032697|reactome:R-SCE-191273 psi-mi:"MI:0469"(intact) crc64:DBA26AF5B769C02A - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:zqDPA3GvKWkMTmH97TcdF8HOHBU559292 intact-crc:37B425C7249DBB6B|rigid:W7GYUgk97Sp49oNQ80b8A3OgSXU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38604 uniprotkb:P28321 intact:EBI-6572|uniprotkb:Q92327|uniprotkb:D3DL21|ensemblfungi:YHR072W intact:EBI-26790|uniprotkb:D6VXJ4|ensemblfungi:YKL094W psi-mi:erg7_yeast(display_long)|uniprotkb:Oxidosqualene--lanosterol cyclase(gene name synonym)|uniprotkb:2,3-epoxysqualene--lanosterol cyclase(gene name synonym)|uniprotkb:YHR072W(locus name)|uniprotkb:ERG7(gene name)|psi-mi:ERG7(display_short) psi-mi:mgll_yeast(display_long)|uniprotkb:YJU3(gene name)|psi-mi:YJU3(display_short)|uniprotkb:Monoacylglycerol hydrolase(gene name synonym)|uniprotkb:Monoacylglycerol lipase(gene name synonym)|uniprotkb:Serine hydrolase YJU3(gene name synonym)|uniprotkb:YKL441(orf name)|uniprotkb:YKL094W(locus name)|uniprotkb:Fatty acid ethyl ester hydrolase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328551|imex:IM-14275-1330 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011939.2|sgd:S000001114|mint:P38604|dip:DIP-8319N|ensemblfungi:YHR072W(gene)|ensemblfungi:YHR072W_mRNA(transcript)|go:"GO:0000250"(lanosterol synthase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016104"(triterpenoid biosynthetic process)|go:"GO:0042300"(beta-amyrin synthase activity)|interpro:IPR002365(Terpene synthase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR018333|interpro:IPR032696|interpro:IPR032697|reactome:R-SCE-191273 interpro:IPR022742|refseq:NP_012829.1|sgd:S000001577|mint:P28321|interpro:IPR029058|ensemblfungi:YKL094W(gene)|ensemblfungi:YKL094W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0071944"(cell periphery)|rcsb pdb:4ZWN|rcsb pdb:4ZXF psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zqDPA3GvKWkMTmH97TcdF8HOHBU559292 rogid:IHpY1aez3MG+bn7bThCBdvE6KMw559292 intact-crc:0B5DF33F736322A1|rigid:lxxRMG8fteXLl7JaKpd/kmdokEw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35196 uniprotkb:P38604 intact:EBI-14943|uniprotkb:D6VQ03|ensemblfungi:YBR002C intact:EBI-6572|uniprotkb:Q92327|uniprotkb:D3DL21|ensemblfungi:YHR072W psi-mi:rer2_yeast(display_long)|uniprotkb:"Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific)"(gene name synonym)|uniprotkb:YBR0107(orf name)|uniprotkb:RER2(gene name)|psi-mi:RER2(display_short)|uniprotkb:YBR002C(locus name) psi-mi:erg7_yeast(display_long)|uniprotkb:Oxidosqualene--lanosterol cyclase(gene name synonym)|uniprotkb:2,3-epoxysqualene--lanosterol cyclase(gene name synonym)|uniprotkb:YHR072W(locus name)|uniprotkb:ERG7(gene name)|psi-mi:ERG7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328562|imex:IM-14275-1331 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036424|refseq:NP_009556.1|sgd:S000000206|interpro:IPR001441(Di-trans-poly-cis-decaprenylcistransferase)|interpro:IPR018520|ensemblfungi:YBR002C(gene)|ensemblfungi:YBR002C_mRNA(transcript)|go:"GO:0002094"(polyprenyltransferase activity)|go:"GO:0004659"(prenyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016094"(polyprenol biosynthetic process)|go:"GO:0019408"(dolichol biosynthetic process)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0045547"(dehydrodolichyl diphosphate synthase activity)|go:"GO:1904423"(dehydrodolichyl diphosphate synthase complex)|reactome:R-SCE-446199|mint:P35196 refseq:NP_011939.2|sgd:S000001114|mint:P38604|dip:DIP-8319N|ensemblfungi:YHR072W(gene)|ensemblfungi:YHR072W_mRNA(transcript)|go:"GO:0000250"(lanosterol synthase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016104"(triterpenoid biosynthetic process)|go:"GO:0042300"(beta-amyrin synthase activity)|interpro:IPR002365(Terpene synthase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR018333|interpro:IPR032696|interpro:IPR032697|reactome:R-SCE-191273 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:gVl9E/6GKqKsUp/5VLdT5XGbjUM559292 rogid:zqDPA3GvKWkMTmH97TcdF8HOHBU559292 intact-crc:0163F542082AE451|rigid:Wvk1TWV0UNsyTaOfMhFvVOGM+g8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38225 uniprotkb:P38604 intact:EBI-6819|uniprotkb:O60021|uniprotkb:Q86ZS3|uniprotkb:D6VQ41|ensemblfungi:YBR041W intact:EBI-6572|uniprotkb:Q92327|uniprotkb:D3DL21|ensemblfungi:YHR072W psi-mi:fat1_yeast(display_long)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:Very-long-chain acyl-CoA synthetase(gene name synonym)|uniprotkb:YBR0411(orf name)|uniprotkb:YBR041W(locus name) psi-mi:erg7_yeast(display_long)|uniprotkb:Oxidosqualene--lanosterol cyclase(gene name synonym)|uniprotkb:2,3-epoxysqualene--lanosterol cyclase(gene name synonym)|uniprotkb:YHR072W(locus name)|uniprotkb:ERG7(gene name)|psi-mi:ERG7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328573|imex:IM-14275-1332 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009597.2|sgd:S000000245|mint:P38225|dip:DIP-5048N|ensemblfungi:YBR041W(gene)|ensemblfungi:YBR041W_mRNA(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0071944"(cell periphery)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR030310|interpro:IPR042099|reactome:R-SCE-159418|reactome:R-SCE-193368|reactome:R-SCE-193775|reactome:R-SCE-389599|reactome:R-SCE-6798695|reactome:R-SCE-804914|reactome:R-SCE-9033241 refseq:NP_011939.2|sgd:S000001114|mint:P38604|dip:DIP-8319N|ensemblfungi:YHR072W(gene)|ensemblfungi:YHR072W_mRNA(transcript)|go:"GO:0000250"(lanosterol synthase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016104"(triterpenoid biosynthetic process)|go:"GO:0042300"(beta-amyrin synthase activity)|interpro:IPR002365(Terpene synthase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR018333|interpro:IPR032696|interpro:IPR032697|reactome:R-SCE-191273 psi-mi:"MI:0469"(intact) crc64:509A5DEDDEE98823 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mGjvEcQ/ZVHp/P+89KaQ7DrjcQg559292 rogid:zqDPA3GvKWkMTmH97TcdF8HOHBU559292 intact-crc:3E0B7FA2E781FED4|rigid:dnEAozRQkv0WBE/Bt6tFqp/hO/4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38604 uniprotkb:P38604 intact:EBI-6572|uniprotkb:Q92327|uniprotkb:D3DL21|ensemblfungi:YHR072W intact:EBI-6572|uniprotkb:Q92327|uniprotkb:D3DL21|ensemblfungi:YHR072W psi-mi:erg7_yeast(display_long)|uniprotkb:Oxidosqualene--lanosterol cyclase(gene name synonym)|uniprotkb:2,3-epoxysqualene--lanosterol cyclase(gene name synonym)|uniprotkb:YHR072W(locus name)|uniprotkb:ERG7(gene name)|psi-mi:ERG7(display_short) psi-mi:erg7_yeast(display_long)|uniprotkb:Oxidosqualene--lanosterol cyclase(gene name synonym)|uniprotkb:2,3-epoxysqualene--lanosterol cyclase(gene name synonym)|uniprotkb:YHR072W(locus name)|uniprotkb:ERG7(gene name)|psi-mi:ERG7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328584|imex:IM-14275-1333 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011939.2|sgd:S000001114|mint:P38604|dip:DIP-8319N|ensemblfungi:YHR072W(gene)|ensemblfungi:YHR072W_mRNA(transcript)|go:"GO:0000250"(lanosterol synthase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016104"(triterpenoid biosynthetic process)|go:"GO:0042300"(beta-amyrin synthase activity)|interpro:IPR002365(Terpene synthase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR018333|interpro:IPR032696|interpro:IPR032697|reactome:R-SCE-191273 refseq:NP_011939.2|sgd:S000001114|mint:P38604|dip:DIP-8319N|ensemblfungi:YHR072W(gene)|ensemblfungi:YHR072W_mRNA(transcript)|go:"GO:0000250"(lanosterol synthase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016104"(triterpenoid biosynthetic process)|go:"GO:0042300"(beta-amyrin synthase activity)|interpro:IPR002365(Terpene synthase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR018333|interpro:IPR032696|interpro:IPR032697|reactome:R-SCE-191273 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zqDPA3GvKWkMTmH97TcdF8HOHBU559292 rogid:zqDPA3GvKWkMTmH97TcdF8HOHBU559292 intact-crc:3BB5019E4DFD54CE|rigid:KBkAim4glAjHR6qSdroexLDQEt0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07804 uniprotkb:P38604 intact:EBI-36254|uniprotkb:D6VXZ0|ensemblfungi:YLL012W intact:EBI-6572|uniprotkb:Q92327|uniprotkb:D3DL21|ensemblfungi:YHR072W psi-mi:yeh1_yeast(display_long)|uniprotkb:Steryl ester hydrolase 1(gene name synonym)|uniprotkb:YEH1(gene name)|psi-mi:YEH1(display_short)|uniprotkb:YLL012W(locus name)|uniprotkb:L1329(orf name) psi-mi:erg7_yeast(display_long)|uniprotkb:Oxidosqualene--lanosterol cyclase(gene name synonym)|uniprotkb:2,3-epoxysqualene--lanosterol cyclase(gene name synonym)|uniprotkb:YHR072W(locus name)|uniprotkb:ERG7(gene name)|psi-mi:ERG7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328595|imex:IM-14275-1334 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013089.1|sgd:S000003935|mint:Q07804|dip:DIP-4156N|ensemblfungi:YLL012W(gene)|ensemblfungi:YLL012W_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016125"(sterol metabolic process)|interpro:IPR006693(AB-hydrolase associated lipase region)|interpro:IPR029058|reactome:R-SCE-192456|reactome:R-SCE-6809371 refseq:NP_011939.2|sgd:S000001114|mint:P38604|dip:DIP-8319N|ensemblfungi:YHR072W(gene)|ensemblfungi:YHR072W_mRNA(transcript)|go:"GO:0000250"(lanosterol synthase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016104"(triterpenoid biosynthetic process)|go:"GO:0042300"(beta-amyrin synthase activity)|interpro:IPR002365(Terpene synthase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR018333|interpro:IPR032696|interpro:IPR032697|reactome:R-SCE-191273 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Fv+RBBi6c7i++sW0AISZDXDrlrI559292 rogid:zqDPA3GvKWkMTmH97TcdF8HOHBU559292 intact-crc:20BF2FEF78E4C0E2|rigid:nwSU2n3HF2kfK6pasbaqhLq6lxQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12168 uniprotkb:P38604 intact:EBI-32973|uniprotkb:Q07268|uniprotkb:D6VYD8|ensemblfungi:YLR144C intact:EBI-6572|uniprotkb:Q92327|uniprotkb:D3DL21|ensemblfungi:YHR072W psi-mi:eng2_yeast(display_long)|uniprotkb:ACF2(gene name)|psi-mi:ACF2(display_short)|uniprotkb:YLR144C(locus name)|uniprotkb:Laminarinase-2(gene name synonym)|uniprotkb:ENG2(gene name synonym)|uniprotkb:PCA1(gene name synonym)|uniprotkb:L3180(orf name) psi-mi:erg7_yeast(display_long)|uniprotkb:Oxidosqualene--lanosterol cyclase(gene name synonym)|uniprotkb:2,3-epoxysqualene--lanosterol cyclase(gene name synonym)|uniprotkb:YHR072W(locus name)|uniprotkb:ERG7(gene name)|psi-mi:ERG7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328606|imex:IM-14275-1335 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013245.1|sgd:S000004134|mint:Q12168|dip:DIP-2889N|ensemblfungi:YLR144C(gene)|ensemblfungi:YLR144C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042973"(glucan endo-1,3-beta-D-glucosidase activity)|go:"GO:0052861"(glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group)|go:"GO:0052862"(glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group)|interpro:IPR005200(Glycoside hydrolase, family 81)|interpro:IPR040451|interpro:IPR040720 refseq:NP_011939.2|sgd:S000001114|mint:P38604|dip:DIP-8319N|ensemblfungi:YHR072W(gene)|ensemblfungi:YHR072W_mRNA(transcript)|go:"GO:0000250"(lanosterol synthase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016104"(triterpenoid biosynthetic process)|go:"GO:0042300"(beta-amyrin synthase activity)|interpro:IPR002365(Terpene synthase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR018333|interpro:IPR032696|interpro:IPR032697|reactome:R-SCE-191273 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8STCUe6Ie2CnTTBMjY8wrld5h44559292 rogid:zqDPA3GvKWkMTmH97TcdF8HOHBU559292 intact-crc:1124C57D44C2CD11|rigid:jjWBFeaqPaHCTfzqpibpVTDXix8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25293 uniprotkb:P38615 intact:EBI-11850|uniprotkb:P87196|ensemblfungi:YKR048C|uniprotkb:D6VXA9 intact:EBI-10642|uniprotkb:Q6Q5K4|ensemblfungi:YMR139W|uniprotkb:D6VZW2 psi-mi:nap1_yeast(display_long)|uniprotkb:NAP1(gene name)|psi-mi:NAP1(display_short)|uniprotkb:YKR048C(locus name) psi-mi:rim11_yeast(display_long)|uniprotkb:RIM11(gene name)|psi-mi:RIM11(display_short)|uniprotkb:GSK3(gene name synonym)|uniprotkb:MDS1(gene name synonym)|uniprotkb:YMR139W(locus name)|uniprotkb:YM9375.08(orf name)|uniprotkb:Regulator of IME2 protein 11(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328617|imex:IM-14275-1336 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YKR048C(gene)|ensemblfungi:YKR048C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032153"(cell division site)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0098841"(protein localization to cell division site after cytokinesis)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|rcsb pdb:2AYU|rcsb pdb:2Z2R|rcsb pdb:5G2E|go:"GO:0032174"(cellular bud neck septin collar)|refseq:NP_012974.1|sgd:S000001756|dip:DIP-1380N|mint:P25293 refseq:NP_013859.1|sgd:S000004747|ensemblfungi:YMR139W(gene)|ensemblfungi:YMR139W_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0030437"(ascospore formation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|reactome:R-SCE-3371453|mint:P38615|dip:DIP-1566N psi-mi:"MI:0469"(intact) crc64:C0F97FBA1B9EEA83 crc64:59D92C9D42408E97 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MBxVJ0JmlEg5coqnQd6uoSX2uC0559292 rogid:HR/odTTwzM907syfBEfaJny7t5Q559292 intact-crc:F6091A962269709F|rigid:CYoGLiPL/Kj8Ry8K1dyLggJ6niQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38344 uniprotkb:P38615 intact:EBI-21136|uniprotkb:D6VQR3|ensemblfungi:YBR267W intact:EBI-10642|uniprotkb:Q6Q5K4|ensemblfungi:YMR139W|uniprotkb:D6VZW2 psi-mi:rei1_yeast(display_long)|uniprotkb:REI1(gene name)|psi-mi:REI1(display_short)|uniprotkb:Required for isotropic bud growth protein 1(gene name synonym)|uniprotkb:pre-60S factor REI1(gene name synonym)|uniprotkb:YBR1736(orf name)|uniprotkb:YBR267W(locus name) psi-mi:rim11_yeast(display_long)|uniprotkb:RIM11(gene name)|psi-mi:RIM11(display_short)|uniprotkb:GSK3(gene name synonym)|uniprotkb:MDS1(gene name synonym)|uniprotkb:YMR139W(locus name)|uniprotkb:YM9375.08(orf name)|uniprotkb:Regulator of IME2 protein 11(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328628|imex:IM-14275-1337 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009825.4|sgd:S000000471|mint:P38344|dip:DIP-6347N|rcsb pdb:6RZZ|rcsb pdb:5APN|ensemblfungi:YBR267W(gene)|ensemblfungi:YBR267W_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR040025|interpro:IPR041661 refseq:NP_013859.1|sgd:S000004747|ensemblfungi:YMR139W(gene)|ensemblfungi:YMR139W_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0030437"(ascospore formation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|reactome:R-SCE-3371453|mint:P38615|dip:DIP-1566N psi-mi:"MI:0469"(intact) crc64:D01AA8FFDF4A0BAC crc64:59D92C9D42408E97 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YxMyWWxJUH2Pk41X+98x8jcnqhc559292 rogid:HR/odTTwzM907syfBEfaJny7t5Q559292 intact-crc:CC44AC8B42A264B4|rigid:63Wg14ulXxhH0TaG/C4nUV2XAII false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38615 uniprotkb:P38615 intact:EBI-10642|uniprotkb:Q6Q5K4|ensemblfungi:YMR139W|uniprotkb:D6VZW2 intact:EBI-10642|uniprotkb:Q6Q5K4|ensemblfungi:YMR139W|uniprotkb:D6VZW2 psi-mi:rim11_yeast(display_long)|uniprotkb:RIM11(gene name)|psi-mi:RIM11(display_short)|uniprotkb:GSK3(gene name synonym)|uniprotkb:MDS1(gene name synonym)|uniprotkb:YMR139W(locus name)|uniprotkb:YM9375.08(orf name)|uniprotkb:Regulator of IME2 protein 11(gene name synonym) psi-mi:rim11_yeast(display_long)|uniprotkb:RIM11(gene name)|psi-mi:RIM11(display_short)|uniprotkb:GSK3(gene name synonym)|uniprotkb:MDS1(gene name synonym)|uniprotkb:YMR139W(locus name)|uniprotkb:YM9375.08(orf name)|uniprotkb:Regulator of IME2 protein 11(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328639|imex:IM-14275-1338 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013859.1|sgd:S000004747|ensemblfungi:YMR139W(gene)|ensemblfungi:YMR139W_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0030437"(ascospore formation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|reactome:R-SCE-3371453|mint:P38615|dip:DIP-1566N refseq:NP_013859.1|sgd:S000004747|ensemblfungi:YMR139W(gene)|ensemblfungi:YMR139W_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0030437"(ascospore formation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|reactome:R-SCE-3371453|mint:P38615|dip:DIP-1566N psi-mi:"MI:0469"(intact) crc64:59D92C9D42408E97 crc64:59D92C9D42408E97 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HR/odTTwzM907syfBEfaJny7t5Q559292 rogid:HR/odTTwzM907syfBEfaJny7t5Q559292 intact-crc:BB32B3B7F7E81F1E|rigid:k5EtP+cBMRwt3Eqovljn+zIuA2k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32895 uniprotkb:P38620 intact:EBI-9869|uniprotkb:D6VX20|ensemblfungi:YKL181W intact:EBI-9873|uniprotkb:D3DM06|ensemblfungi:YER099C psi-mi:kpr1_yeast(display_long)|uniprotkb:PPS1(gene name synonym)|uniprotkb:PRP1(gene name synonym)|uniprotkb:PRPS(gene name synonym)|uniprotkb:PRPS1(gene name synonym)|uniprotkb:YKL181W(locus name)|uniprotkb:PRS1(gene name)|psi-mi:PRS1(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 1(gene name synonym) psi-mi:kpr2_yeast(display_long)|uniprotkb:PRPS2(gene name synonym)|uniprotkb:PRS(gene name synonym)|uniprotkb:YER099C(locus name)|uniprotkb:PRS2(gene name)|psi-mi:PRS2(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328650|imex:IM-14275-1339 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012740.1|sgd:S000001664|ensemblfungi:YKL181W(gene)|ensemblfungi:YKL181W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|dip:DIP-4857N|mint:P32895 sgd:S000000901|ensemblfungi:YER099C(gene)|ensemblfungi:YER099C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|refseq:NP_011025.3|dip:DIP-1482N|mint:P38620 psi-mi:"MI:0469"(intact) crc64:F3E93ACB25E703FF crc64:8B970E98084F5D71 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ea45pOje4sjYrrU7ze4Af443yDk559292 rogid:yDbNtDKkeTanVZwDAftGG9nhQCE559292 intact-crc:66544EE6141B94FF|rigid:H7yBj+nssqKKzMhSyeJb5jxCzso false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38063 uniprotkb:P38620 intact:EBI-9882|uniprotkb:Q9HGQ6|ensemblfungi:YBL068W|uniprotkb:D6VPT3 intact:EBI-9873|uniprotkb:D3DM06|ensemblfungi:YER099C psi-mi:kpr4_yeast(display_long)|uniprotkb:PRS4(gene name)|psi-mi:PRS4(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 4(gene name synonym)|uniprotkb:PRPS4(gene name synonym)|uniprotkb:YBL0619(orf name)|uniprotkb:YBL068W(locus name) psi-mi:kpr2_yeast(display_long)|uniprotkb:PRPS2(gene name synonym)|uniprotkb:PRS(gene name synonym)|uniprotkb:YER099C(locus name)|uniprotkb:PRS2(gene name)|psi-mi:PRS2(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328661|imex:IM-14275-1340 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000164|refseq:NP_009485.3|ensemblfungi:YBL068W(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|ensemblfungi:YBL068W_mRNA(transcript)|dip:DIP-3945N|mint:P38063 sgd:S000000901|ensemblfungi:YER099C(gene)|ensemblfungi:YER099C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|refseq:NP_011025.3|dip:DIP-1482N|mint:P38620 psi-mi:"MI:0469"(intact) crc64:B6335D5F1AB1A93C crc64:8B970E98084F5D71 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:elJfRIX/HKbgBlsUI0swFmGheuc559292 rogid:yDbNtDKkeTanVZwDAftGG9nhQCE559292 intact-crc:540AE337A1F2A225|rigid:0fk9Nt4pPozrzQOITcIGPF1MtOw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38620 uniprotkb:P38620 intact:EBI-9873|uniprotkb:D3DM06|ensemblfungi:YER099C intact:EBI-9873|uniprotkb:D3DM06|ensemblfungi:YER099C psi-mi:kpr2_yeast(display_long)|uniprotkb:PRPS2(gene name synonym)|uniprotkb:PRS(gene name synonym)|uniprotkb:YER099C(locus name)|uniprotkb:PRS2(gene name)|psi-mi:PRS2(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 2(gene name synonym) psi-mi:kpr2_yeast(display_long)|uniprotkb:PRPS2(gene name synonym)|uniprotkb:PRS(gene name synonym)|uniprotkb:YER099C(locus name)|uniprotkb:PRS2(gene name)|psi-mi:PRS2(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328672|imex:IM-14275-1341 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000901|ensemblfungi:YER099C(gene)|ensemblfungi:YER099C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|refseq:NP_011025.3|dip:DIP-1482N|mint:P38620 sgd:S000000901|ensemblfungi:YER099C(gene)|ensemblfungi:YER099C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|refseq:NP_011025.3|dip:DIP-1482N|mint:P38620 psi-mi:"MI:0469"(intact) crc64:8B970E98084F5D71 crc64:8B970E98084F5D71 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:yDbNtDKkeTanVZwDAftGG9nhQCE559292 rogid:yDbNtDKkeTanVZwDAftGG9nhQCE559292 intact-crc:AD2C5F026AFB5719|rigid:98CvayhYM9QtgogAgC2/4g8g5/U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38626 uniprotkb:P54837 intact:EBI-2048224|uniprotkb:D6VVN9|ensemblfungi:YIL043C intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:ncb5r_yeast(display_long)|uniprotkb:CBR(gene name synonym)|uniprotkb:CBR5(gene name synonym)|uniprotkb:Microsomal cytochrome b reductase(gene name synonym)|uniprotkb:P35(gene name synonym)|uniprotkb:YIL043C(locus name)|uniprotkb:CBR1(gene name)|psi-mi:CBR1(display_short) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328683|imex:IM-14275-1342 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012221.2|sgd:S000001305|interpro:IPR017927|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR017938|mint:P38626|interpro:IPR039261|ensemblfungi:YIL043C(gene)|ensemblfungi:YIL043C_mRNA(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BxHKVXPxqbv+CNAKhESXsL5hG8k559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:AA57A7DAB4000992|rigid:O0gGCE7lcpJpzWHIr5ohaUQ2l4U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38626 uniprotkb:Q05359 intact:EBI-2048224|uniprotkb:D6VVN9|ensemblfungi:YIL043C intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A psi-mi:ncb5r_yeast(display_long)|uniprotkb:CBR(gene name synonym)|uniprotkb:CBR5(gene name synonym)|uniprotkb:Microsomal cytochrome b reductase(gene name synonym)|uniprotkb:P35(gene name synonym)|uniprotkb:YIL043C(locus name)|uniprotkb:CBR1(gene name)|psi-mi:CBR1(display_short) psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328694|imex:IM-14275-1343 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012221.2|sgd:S000001305|interpro:IPR017927|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR017938|mint:P38626|interpro:IPR039261|ensemblfungi:YIL043C(gene)|ensemblfungi:YIL043C_mRNA(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BxHKVXPxqbv+CNAKhESXsL5hG8k559292 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 intact-crc:B0CEB3F21E15FE24|rigid:9p4VCWYNR54DifXrxYbtD+0+9cU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38626 uniprotkb:Q06144 intact:EBI-2048224|uniprotkb:D6VVN9|ensemblfungi:YIL043C intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:ncb5r_yeast(display_long)|uniprotkb:CBR(gene name synonym)|uniprotkb:CBR5(gene name synonym)|uniprotkb:Microsomal cytochrome b reductase(gene name synonym)|uniprotkb:P35(gene name synonym)|uniprotkb:YIL043C(locus name)|uniprotkb:CBR1(gene name)|psi-mi:CBR1(display_short) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328705|imex:IM-14275-1344 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012221.2|sgd:S000001305|interpro:IPR017927|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR017938|mint:P38626|interpro:IPR039261|ensemblfungi:YIL043C(gene)|ensemblfungi:YIL043C_mRNA(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:2F474503CAB7C195 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BxHKVXPxqbv+CNAKhESXsL5hG8k559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 intact-crc:F36ABB8478E6FE5C|rigid:ssOkDMLgon4w7Oyn3uLLPFG/ZnI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38634 uniprotkb:P35179 intact:EBI-17127|ensemblfungi:YLR079W|uniprotkb:D6VY79 intact:EBI-16406|ensemblfungi:YDR086C|uniprotkb:D6VS73 psi-mi:sic1_yeast(display_long)|uniprotkb:SIC1(gene name)|psi-mi:SIC1(display_short)|uniprotkb:SDB25(gene name synonym)|uniprotkb:YLR079W(locus name)|uniprotkb:L9449.8(orf name)|uniprotkb:CDK inhibitor p40(gene name synonym) psi-mi:sc61g_yeast(display_long)|uniprotkb:Sec61 complex subunit SSS1(gene name synonym)|uniprotkb:Ssh1 complex subunit SSS1(gene name synonym)|uniprotkb:D4475(orf name)|uniprotkb:YDR086C(locus name)|uniprotkb:SSS1(gene name)|psi-mi:SSS1(display_short)|uniprotkb:Sec61 complex subunit gamma(gene name synonym)|uniprotkb:Ssh1 complex subunit gamma(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328716|imex:IM-14275-1345 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR079W(gene)|ensemblfungi:YLR079W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016242"(negative regulation of macroautophagy)|rcsb pdb:3V7D|rcsb pdb:6G86|refseq:NP_013180.1|sgd:S000004069|dip:DIP-6817N|mint:P38634 ensemblfungi:YDR086C(gene)|ensemblfungi:YDR086C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|rcsb pdb:2WW9|rcsb pdb:2WWA|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|reactome:R-SCE-9609523|refseq:NP_010371.1|sgd:S000002493|dip:DIP-2432N|mint:P35179 psi-mi:"MI:0469"(intact) crc64:7913636340678F78 - figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:qU8ivBCZHvG4VmXDxv52yc08Hwc559292 rogid:QIi5kN/8mDxTSvxRiJVi2JsPdws559292 intact-crc:55CD3E6584302AFE|rigid:h4jRrkaYyWPY0J/JI911ba2AJxk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25584 uniprotkb:P38635 intact:EBI-21765|uniprotkb:D6VQW1|ensemblfungi:YCL056C intact:EBI-2045554|uniprotkb:D6VTQ5|ensemblfungi:YFR025C psi-mi:pex34_yeast(display_long)|uniprotkb:YCL056C(locus name)|uniprotkb:YCL56C(orf name)|uniprotkb:YCL433(orf name)|uniprotkb:PEX34(gene name)|psi-mi:PEX34(display_short)|uniprotkb:Peroxin-34(gene name synonym) psi-mi:his9_yeast(display_long)|uniprotkb:YFR025C(locus name)|uniprotkb:HIS2(gene name)|psi-mi:HIS2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328727|imex:IM-14275-1346 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000561|refseq:NP_009875.1|mint:P25584|dip:DIP-2040N|ensemblfungi:YCL056C(gene)|ensemblfungi:YCL056C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization) refseq:NP_116681.1|sgd:S000001921|interpro:IPR010140(Histidinol phosphate phosphatase, HisJ)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|mint:P38635|ensemblfungi:YFR025C(gene)|ensemblfungi:YFR025C_mRNA(transcript)|go:"GO:0000105"(histidine biosynthetic process)|go:"GO:0004401"(histidinol-phosphatase activity)|go:"GO:0005737"(cytoplasm) psi-mi:"MI:0469"(intact) crc64:6035D449766516A6 - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IGoLOZeCbBNA4w+BG9mC/vxGfqs559292 rogid:3gGqFDbJWtM4it1O4HJjk6KoTL4559292 intact-crc:C4582B8F595C1A19|rigid:3O6h3OwBjpyHmeUtZS/euakUhx8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38635 uniprotkb:Q96VH3 intact:EBI-2045554|uniprotkb:D6VTQ5|ensemblfungi:YFR025C intact:EBI-2044941|uniprotkb:D6VQZ3|ensemblfungi:YCL021W-A psi-mi:his9_yeast(display_long)|uniprotkb:YFR025C(locus name)|uniprotkb:HIS2(gene name)|psi-mi:HIS2(display_short) psi-mi:yc021_yeast(display_long)|uniprotkb:YCL021W-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328738|imex:IM-14275-1347 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116681.1|sgd:S000001921|interpro:IPR010140(Histidinol phosphate phosphatase, HisJ)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|mint:P38635|ensemblfungi:YFR025C(gene)|ensemblfungi:YFR025C_mRNA(transcript)|go:"GO:0000105"(histidine biosynthetic process)|go:"GO:0004401"(histidinol-phosphatase activity)|go:"GO:0005737"(cytoplasm) sgd:S000007549|refseq:NP_065437.1|mint:Q96VH3|ensemblfungi:YCL021W-A(gene)|ensemblfungi:YCL021W-A_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3gGqFDbJWtM4it1O4HJjk6KoTL4559292 rogid:KPtxCFX4m13AghkJuoOkuTMuIWA559292 intact-crc:FACE16B35B3C439A|rigid:sxu6aN9c2zsya6bClvMZSn8A9+U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38688 uniprotkb:P38985 intact:EBI-18011|uniprotkb:D6W3G0|ensemblfungi:YPL210C intact:EBI-17977|uniprotkb:D6VRQ6|ensemblfungi:YDL092W psi-mi:srp72_yeast(display_long)|uniprotkb:YPL210C(locus name)|uniprotkb:SRP72(gene name)|psi-mi:SRP72(display_short)|uniprotkb:Signal recognition particle 72 kDa protein homolog(gene name synonym) psi-mi:srp14_yeast(display_long)|uniprotkb:SRP14(gene name)|psi-mi:SRP14(display_short)|uniprotkb:YDL092W(locus name)|uniprotkb:D2404(orf name)|uniprotkb:Signal recognition particle 14 kDa protein homolog(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328749|imex:IM-14275-1348 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015114.2|sgd:S000006131|reactome:R-SCE-1799339|ensemblfungi:YPL210C(gene)|ensemblfungi:YPL210C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013699(Signal recognition particle, SRP72 subunit, RNA-binding)|interpro:IPR026270|dip:DIP-6763N|mint:P38688 refseq:NP_010191.1|sgd:S000002250|ensemblfungi:YDL092W(gene)|ensemblfungi:YDL092W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR003210(Signal recognition particle, SRP14 subunit)|interpro:IPR009018(Signal recognition particle, SRP9/SRP14 subunit)|reactome:R-SCE-1799339|reactome:R-SCE-6798695|dip:DIP-4864N|mint:P38985 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:yhhZC25wybDaN4LOKK6P4/TPnRE559292 rogid:I9myDFdKPRnrKsHBhWBxI/Em7EQ559292 intact-crc:0FC5A1310A2411DD|rigid:ZGt8A06obiZQXCaJkDdQu41Ehvg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38689 uniprotkb:P38689 intact:EBI-9877|uniprotkb:D3DKQ2|ensemblfungi:YHL011C intact:EBI-9877|uniprotkb:D3DKQ2|ensemblfungi:YHL011C psi-mi:kpr3_yeast(display_long)|uniprotkb:PRS3(gene name)|psi-mi:PRS3(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 3(gene name synonym)|uniprotkb:PRPS3(gene name synonym)|uniprotkb:YHL011C(locus name) psi-mi:kpr3_yeast(display_long)|uniprotkb:PRS3(gene name)|psi-mi:PRS3(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 3(gene name synonym)|uniprotkb:PRPS3(gene name synonym)|uniprotkb:YHL011C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328760|imex:IM-14275-1349 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011852.1|sgd:S000001003|ensemblfungi:YHL011C(gene)|ensemblfungi:YHL011C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|dip:DIP-4307N|mint:P38689 refseq:NP_011852.1|sgd:S000001003|ensemblfungi:YHL011C(gene)|ensemblfungi:YHL011C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|dip:DIP-4307N|mint:P38689 psi-mi:"MI:0469"(intact) crc64:D4839D217B7513C4 crc64:D4839D217B7513C4 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8Km+h9PM9lJSTwLUTObbTkNkKig559292 rogid:8Km+h9PM9lJSTwLUTObbTkNkKig559292 intact-crc:1BD5B77B67EDD404|rigid:1s8B3d87Ecgw31P97FN3Z9XMY78 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38689 uniprotkb:Q12265 intact:EBI-9877|uniprotkb:D3DKQ2|ensemblfungi:YHL011C intact:EBI-9886|ensemblfungi:YOL061W|uniprotkb:D6W206 psi-mi:kpr3_yeast(display_long)|uniprotkb:PRS3(gene name)|psi-mi:PRS3(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 3(gene name synonym)|uniprotkb:PRPS3(gene name synonym)|uniprotkb:YHL011C(locus name) psi-mi:kpr5_yeast(display_long)|uniprotkb:PRS5(gene name)|psi-mi:PRS5(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 5(gene name synonym)|uniprotkb:PRPS5(gene name synonym)|uniprotkb:O1213(orf name)|uniprotkb:YOL061W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328771|imex:IM-14275-1350 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011852.1|sgd:S000001003|ensemblfungi:YHL011C(gene)|ensemblfungi:YHL011C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|dip:DIP-4307N|mint:P38689 refseq:NP_014580.1|sgd:S000005422|ensemblfungi:YOL061W(gene)|ensemblfungi:YOL061W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|dip:DIP-1532N|mint:Q12265 psi-mi:"MI:0469"(intact) crc64:D4839D217B7513C4 crc64:75C948D40D58256D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8Km+h9PM9lJSTwLUTObbTkNkKig559292 rogid:vnGVKU7vl2NG7lgcrlTVSHYYQMI559292 intact-crc:5A4A5B0A42978135|rigid:DRxtbWySbkHFtWdZvv6tg3SxW6k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38694 uniprotkb:Q06144 intact:EBI-24511|uniprotkb:D3DKY6|ensemblfungi:YHR039C intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:msc7_yeast(display_long)|uniprotkb:MSC7(gene name)|psi-mi:MSC7(display_short)|uniprotkb:Meiotic sister-chromatid recombination protein 7(gene name synonym)|uniprotkb:YHR039C(locus name) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328782|imex:IM-14275-1351 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011904.1|sgd:S000001081|dip:DIP-1878N|mint:P38694|ensemblfungi:YHR039C(gene)|ensemblfungi:YHR039C_mRNA(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007131"(reciprocal meiotic recombination)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510 refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:2F474503CAB7C195 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p2xtb6/xYI/jfPNtO6JRZs+5t6I559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 intact-crc:5BCD8A3D2A3988B2|rigid:tw/z5li5dV4XGxs9n/vJYLplW/8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38695 uniprotkb:P19807 intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328793|imex:IM-14275-1352 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) crc64:6906721BAC1A5F87 - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:7EF5AE0064DAA013|rigid:JyXBTx9WaC4TF7Bm+bjqpt2/8iA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38695 uniprotkb:P38695 intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328804|imex:IM-14275-1353 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N psi-mi:"MI:0469"(intact) crc64:6906721BAC1A5F87 crc64:6906721BAC1A5F87 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 intact-crc:4AC77BEEE32C712E|rigid:1CkdsQ+dbgqhq7BwyzIeKNP8dJk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38695 uniprotkb:P40474 intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328815|imex:IM-14275-1354 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:6906721BAC1A5F87 - figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 intact-crc:2E96F5426311FF78|rigid:wSZ06Quj7kwb52beSrzFldGNeMw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38695 uniprotkb:P50276 intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328826|imex:IM-14275-1355 author score:99.36 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) crc64:6906721BAC1A5F87 - figure legend:tables S3 and S4|author-confidence:99.36|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:23EBEDC94D9494CE|rigid:LL2cXDwOqA8EDshc5EsUhSFNaF4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38695 uniprotkb:P53283 intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328837|imex:IM-14275-1356 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:6906721BAC1A5F87 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 intact-crc:0E117C2FF77AB6CE|rigid:eeTtRNE+cPmOQAz+Fh4qKxGTVLs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53388 uniprotkb:P38695 intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328848|imex:IM-14275-1357 author score:99.36 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N psi-mi:"MI:0469"(intact) crc64:488A382656039D0B crc64:6906721BAC1A5F87 figure legend:tables S3 and S4|author-confidence:99.36|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 intact-crc:8C46C51DBDE28360|rigid:4xM2CyqmrJeIELrnxuAtKeNXm8s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38695 uniprotkb:Q02785 intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328859|imex:IM-14275-1358 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) crc64:6906721BAC1A5F87 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:47EC9B52C5F47981|rigid:fmYzjeDVi8DdQzSDfK1G9Ee00oI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:P38695 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328870|imex:IM-14275-1359 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 crc64:6906721BAC1A5F87 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 intact-crc:09DC9E7F6C442EDC|rigid:mtGY21Rlb7jv1M08+skaSom8ojg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38695 uniprotkb:Q06451 intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 intact:EBI-34275|uniprotkb:D6W4F2|ensemblfungi:YPR156C psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:tpo3_yeast(display_long)|uniprotkb:TPO3(gene name)|psi-mi:TPO3(display_short)|uniprotkb:P9584.7(orf name)|uniprotkb:YPR156C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328881|imex:IM-14275-1360 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N refseq:NP_015482.1|sgd:S000006360|mint:Q06451|dip:DIP-3907N|ensemblfungi:YPR156C(gene)|ensemblfungi:YPR156C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:6906721BAC1A5F87 crc64:D260ED161F800502 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 rogid:oVpx7Bjk/mK2Q7+/j05tX3gHw7k559292 intact-crc:28DA870124FE718C|rigid:Xh0uh7TLML993cPLsOVP2zFqDOQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P38695 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328892|imex:IM-14275-1361 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N psi-mi:"MI:0469"(intact) - crc64:6906721BAC1A5F87 figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 intact-crc:49C01A4C8BB91C41|rigid:ReSZCIDD7flT6ywJqNzZn49cyXM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38695 uniprotkb:Q07824 intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328903|imex:IM-14275-1362 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:6906721BAC1A5F87 - figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 intact-crc:B76D4E9DA8800546|rigid:3yTxw+SH2HYujGHFc6kd7EW7iCE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38695 uniprotkb:Q3E756 intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 intact:EBI-2044812|uniprotkb:D6VPX0|ensemblfungi:YBL029C-A psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:yb029_yeast(display_long)|uniprotkb:YBL029C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328914|imex:IM-14275-1363 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N sgd:S000007591|refseq:NP_076874.1|mint:Q3E756|ensemblfungi:YBL029C-A(gene)|ensemblfungi:YBL029C-A_mRNA(transcript)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) crc64:6906721BAC1A5F87 - figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 rogid:Y9LDkESr65DK5SLFNTw1dBKeqPc559292 intact-crc:21D2355E39F41818|rigid:14UMfoBUUm7oPkwaxsKev6PnjUE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25302 uniprotkb:P38699 intact:EBI-18626|ensemblfungi:YER111C|uniprotkb:D3DM17 intact:EBI-18333|uniprotkb:D3DLC7|ensemblfungi:YHR178W psi-mi:swi4_yeast(display_long)|uniprotkb:SWI4(gene name)|psi-mi:SWI4(display_short)|uniprotkb:ART1(gene name synonym)|uniprotkb:YER111C(locus name)|uniprotkb:Cell-cycle box factor subunit SWI4(gene name synonym)|uniprotkb:Protein ART1(gene name synonym) psi-mi:stb5_yeast(display_long)|uniprotkb:STB5(gene name)|psi-mi:STB5(display_short)|uniprotkb:YHR178W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328925|imex:IM-14275-1364 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER111C(gene)|ensemblfungi:YER111C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0030907"(MBF transcription complex)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR003163(DNA-binding, yeast)|interpro:IPR018004|interpro:IPR029792|interpro:IPR036770|interpro:IPR036887|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|refseq:NP_011036.1|sgd:S000000913|dip:DIP-847N|mint:P25302 sgd:S000001221|ensemblfungi:YHR178W(gene)|ensemblfungi:YHR178W_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR007219(Fungal specific transcription factor)|interpro:IPR036864|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|refseq:NP_012048.3|dip:DIP-827N|mint:P38699 psi-mi:"MI:0469"(intact) crc64:40EA2EA7732687A9 - figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:LlB1EIrlcujhBYs6ipXPlRaWf+A559292 rogid:syVKYteUPjiuwtyeUSaIN0U03sQ559292 intact-crc:E452F502371EC9F8|rigid:AJtky6fo4R/8mjUcktGOjGpm5Q4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38715 uniprotkb:P38715 intact:EBI-7884|uniprotkb:D3DL54|ensemblfungi:YHR104W intact:EBI-7884|uniprotkb:D3DL54|ensemblfungi:YHR104W psi-mi:gre3_yeast(display_long)|uniprotkb:GRE3(gene name)|psi-mi:GRE3(display_short)|uniprotkb:NADPH-dependent aldo-keto reductase GRE3(gene name synonym)|uniprotkb:Xylose reductase(gene name synonym)|uniprotkb:Genes de respuesta a estres protein 3(gene name synonym)|uniprotkb:YHR104W(locus name) psi-mi:gre3_yeast(display_long)|uniprotkb:GRE3(gene name)|psi-mi:GRE3(display_short)|uniprotkb:NADPH-dependent aldo-keto reductase GRE3(gene name synonym)|uniprotkb:Xylose reductase(gene name synonym)|uniprotkb:Genes de respuesta a estres protein 3(gene name synonym)|uniprotkb:YHR104W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328936|imex:IM-14275-1365 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018170|interpro:IPR020471|interpro:IPR023210|refseq:NP_011972.1|sgd:S000001146|interpro:IPR036812|mint:P38715|ensemblfungi:YHR104W(gene)|ensemblfungi:YHR104W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004032"("alditol:NADP+ 1-oxidoreductase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0019388"(galactose catabolic process)|go:"GO:0019568"(arabinose catabolic process)|go:"GO:0032866"("D-xylose:NADP reductase activity")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042843"(D-xylose catabolic process)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0071470"(cellular response to osmotic stress) interpro:IPR018170|interpro:IPR020471|interpro:IPR023210|refseq:NP_011972.1|sgd:S000001146|interpro:IPR036812|mint:P38715|ensemblfungi:YHR104W(gene)|ensemblfungi:YHR104W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004032"("alditol:NADP+ 1-oxidoreductase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0019388"(galactose catabolic process)|go:"GO:0019568"(arabinose catabolic process)|go:"GO:0032866"("D-xylose:NADP reductase activity")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042843"(D-xylose catabolic process)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0071470"(cellular response to osmotic stress) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TliGdJT/Tc6gAKeyRBmLB/2RQ94559292 rogid:TliGdJT/Tc6gAKeyRBmLB/2RQ94559292 intact-crc:0A8C8D0EFCCA8793|rigid:LX3pryu8YcFBQF911Uiw4FuB6XU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38715 uniprotkb:P54783 intact:EBI-7884|uniprotkb:D3DL54|ensemblfungi:YHR104W intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:gre3_yeast(display_long)|uniprotkb:GRE3(gene name)|psi-mi:GRE3(display_short)|uniprotkb:NADPH-dependent aldo-keto reductase GRE3(gene name synonym)|uniprotkb:Xylose reductase(gene name synonym)|uniprotkb:Genes de respuesta a estres protein 3(gene name synonym)|uniprotkb:YHR104W(locus name) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328947|imex:IM-14275-1366 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018170|interpro:IPR020471|interpro:IPR023210|refseq:NP_011972.1|sgd:S000001146|interpro:IPR036812|mint:P38715|ensemblfungi:YHR104W(gene)|ensemblfungi:YHR104W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004032"("alditol:NADP+ 1-oxidoreductase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0019388"(galactose catabolic process)|go:"GO:0019568"(arabinose catabolic process)|go:"GO:0032866"("D-xylose:NADP reductase activity")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042843"(D-xylose catabolic process)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0071470"(cellular response to osmotic stress) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TliGdJT/Tc6gAKeyRBmLB/2RQ94559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:57D84D9CD23A87A9|rigid:gUgXazWWab+1T3dgfEBjnwpGQOo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38723 uniprotkb:P10614 intact:EBI-4985|uniprotkb:D3DKS3|ensemblfungi:YHL048W intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:cos8_yeast(display_long)|uniprotkb:COS8(gene name)|psi-mi:COS8(display_short)|uniprotkb:YHL048W(locus name) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328958|imex:IM-14275-1367 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001040|refseq:NP_011815.1|dip:DIP-4866N|mint:P38723|ensemblfungi:YHL048W(gene)|ensemblfungi:YHL048W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005635"(nuclear envelope)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|interpro:IPR001142(Yeast membrane protein DUP) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6s10gJSyOkapuAGoJoFownQG3bE559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:0658612D2B8D6ADC|rigid:Je/97cu2krA86/oMvu34oBObwv0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25366 uniprotkb:P38738 intact:EBI-22021|uniprotkb:D6VR95|ensemblfungi:YCR095C intact:EBI-24355|uniprotkb:D3DKT9|ensemblfungi:YHL029C psi-mi:oca4_yeast(display_long)|uniprotkb:YCR095C(locus name)|uniprotkb:YCR95C(orf name)|uniprotkb:YCR131(orf name)|uniprotkb:OCA4(gene name)|psi-mi:OCA4(display_short)|uniprotkb:Oxidant-induced cell-cycle arrest protein 4(gene name synonym) psi-mi:oca5_yeast(display_long)|uniprotkb:OCA5(gene name)|psi-mi:OCA5(display_short)|uniprotkb:YHL029C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328969|imex:IM-14275-1368 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010019.1|sgd:S000000691|dip:DIP-5005N|ensemblfungi:YCR095C(gene)|ensemblfungi:YCR095C_mRNA(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR004861(Protein-tyrosine phosphatase, SIW14-like)|interpro:IPR029021|mint:P25366 refseq:NP_011834.1|sgd:S000001021|dip:DIP-5006N|mint:P38738|ensemblfungi:YHL029C(gene)|ensemblfungi:YHL029C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969 psi-mi:"MI:0469"(intact) crc64:B927AE5248F4B51F crc64:AA2C5434FFDD881A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HhFkTrTIerLTxg4/Po+AYG/Vqtk559292 rogid:EuUe4RzvDUFrPvVH39f6uH+yKw0559292 intact-crc:DBB228A08AC18C4F|rigid:Y61Tw5OaUbWSh+MynWq/BioYiu8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38749 uniprotkb:Q06132 intact:EBI-24313|uniprotkb:D3DKQ4|ensemblfungi:YHL009C intact:EBI-34377|uniprotkb:D6VYX6|ensemblfungi:YLR336C psi-mi:yap3_yeast(display_long)|uniprotkb:YAP3(gene name)|psi-mi:YAP3(display_short)|uniprotkb:YHL009C(locus name) psi-mi:sgd1_yeast(display_long)|uniprotkb:SGD1(gene name)|psi-mi:SGD1(display_short)|uniprotkb:YLR336C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328980|imex:IM-14275-1369 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011854.1|sgd:S000001001|dip:DIP-1668N|mint:P38749|ensemblfungi:YHL009C(gene)|ensemblfungi:YHL009C_mRNA(transcript)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor") refseq:NP_013440.1|sgd:S000004328|mint:Q06132|dip:DIP-6333N|ensemblfungi:YLR336C(gene)|ensemblfungi:YLR336C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097078"(FAL1-SGD1 complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold) psi-mi:"MI:0469"(intact) - crc64:8EEFDB8258407FF3 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vCk8sZnPOttzOt391KEgOSYCC1Q559292 rogid:FxZCxGejbcvEs/J2h1HEaWeVZLQ559292 intact-crc:26C7FEEB940D55CB|rigid:ZqX/8JfXuG1RZyNAYg7ABy2Ji0E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38753 uniprotkb:P38753 intact:EBI-1382|uniprotkb:D3DKR2|ensemblfungi:YHL002W intact:EBI-1382|uniprotkb:D3DKR2|ensemblfungi:YHL002W psi-mi:hse1_yeast(display_long)|uniprotkb:YHL002W(locus name)|uniprotkb:HSE1(gene name)|psi-mi:HSE1(display_short) psi-mi:hse1_yeast(display_long)|uniprotkb:YHL002W(locus name)|uniprotkb:HSE1(gene name)|psi-mi:HSE1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6328991|imex:IM-14275-1370 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011861.1|sgd:S000000994|ensemblfungi:YHL002W(gene)|ensemblfungi:YHL002W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046982"(protein heterodimerization activity)|dip:DIP-1742N|mint:P38753|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR036028|rcsb pdb:2PJW refseq:NP_011861.1|sgd:S000000994|ensemblfungi:YHL002W(gene)|ensemblfungi:YHL002W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046982"(protein heterodimerization activity)|dip:DIP-1742N|mint:P38753|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR036028|rcsb pdb:2PJW psi-mi:"MI:0469"(intact) crc64:026267836BBADF69 crc64:026267836BBADF69 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hPRFtB/ZQ4DL37gCH3EvSxwbW7w559292 rogid:hPRFtB/ZQ4DL37gCH3EvSxwbW7w559292 intact-crc:55E053ED258424FD|rigid:6QFZgPF11xC2mIRPaJBFFounOiE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40343 uniprotkb:P38753 intact:EBI-20380|uniprotkb:D6W1I1|ensemblfungi:YNR006W intact:EBI-1382|uniprotkb:D3DKR2|ensemblfungi:YHL002W psi-mi:vps27_yeast(display_long)|uniprotkb:VPS27(gene name)|psi-mi:VPS27(display_short)|uniprotkb:YNR006W(locus name)|uniprotkb:N2038(orf name)|uniprotkb:DID7(gene name synonym)|uniprotkb:SSV17(gene name synonym)|uniprotkb:VPL23(gene name synonym)|uniprotkb:VPT27(gene name synonym)|uniprotkb:Golgi retention defective protein 11(gene name synonym)|uniprotkb:GRD11(gene name synonym) psi-mi:hse1_yeast(display_long)|uniprotkb:YHL002W(locus name)|uniprotkb:HSE1(gene name)|psi-mi:HSE1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329002|imex:IM-14275-1371 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005289|refseq:NP_014403.3|ensemblfungi:YNR006W(gene)|ensemblfungi:YNR006W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0140504"(microlipophagy)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|rcsb pdb:1O06|rcsb pdb:1Q0V|rcsb pdb:1Q0W|rcsb pdb:1VFY|rcsb pdb:2KDI|rcsb pdb:2PJW|rcsb pdb:3R42|rcsb pdb:6NJG|dip:DIP-1741N|mint:P40343 refseq:NP_011861.1|sgd:S000000994|ensemblfungi:YHL002W(gene)|ensemblfungi:YHL002W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046982"(protein heterodimerization activity)|dip:DIP-1742N|mint:P38753|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR036028|rcsb pdb:2PJW psi-mi:"MI:0469"(intact) crc64:76C4501B0EBC9C84 crc64:026267836BBADF69 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5ScB34gSI3x260kAGh/knEWupwA559292 rogid:hPRFtB/ZQ4DL37gCH3EvSxwbW7w559292 intact-crc:118E2249794F47AF|rigid:v536EqE/Gha39qmMZnLdHb6nDzY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38755 uniprotkb:P10823 intact:EBI-12641|uniprotkb:D3DKR7|ensemblfungi:YHR001W intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:osh7_yeast(display_long)|uniprotkb:YHR001W(locus name)|uniprotkb:OSH7(gene name)|psi-mi:OSH7(display_short) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329013|imex:IM-14275-1372 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR001W(gene)|ensemblfungi:YHR001W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_011863.1|sgd:S000001043|mint:P38755|dip:DIP-6363N sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) crc64:1C972ED6517D529B crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CnsyJOWY7SpdJZ6GeUshxYiBNJk559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:B6EA88073AD84502|rigid:0I3VkCuL71lnYI29aqhEwpP9LBM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:P38755 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-12641|uniprotkb:D3DKR7|ensemblfungi:YHR001W psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:osh7_yeast(display_long)|uniprotkb:YHR001W(locus name)|uniprotkb:OSH7(gene name)|psi-mi:OSH7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329024|imex:IM-14275-1373 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) ensemblfungi:YHR001W(gene)|ensemblfungi:YHR001W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_011863.1|sgd:S000001043|mint:P38755|dip:DIP-6363N psi-mi:"MI:0469"(intact) - crc64:1C972ED6517D529B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:CnsyJOWY7SpdJZ6GeUshxYiBNJk559292 intact-crc:9E20AEACC644F66C|rigid:ja5hymtGb4wiicxHHfUlwVw2iMw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25619 uniprotkb:P38755 intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C intact:EBI-12641|uniprotkb:D3DKR7|ensemblfungi:YHR001W psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:osh7_yeast(display_long)|uniprotkb:YHR001W(locus name)|uniprotkb:OSH7(gene name)|psi-mi:OSH7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329035|imex:IM-14275-1374 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 ensemblfungi:YHR001W(gene)|ensemblfungi:YHR001W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_011863.1|sgd:S000001043|mint:P38755|dip:DIP-6363N psi-mi:"MI:0469"(intact) crc64:260474A481D29AC5 crc64:1C972ED6517D529B figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 rogid:CnsyJOWY7SpdJZ6GeUshxYiBNJk559292 intact-crc:B697364F051E4FA2|rigid:tBiLXk79zMhOD2ZjBrUS4kKyqLo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38755 uniprotkb:P33413 intact:EBI-12641|uniprotkb:D3DKR7|ensemblfungi:YHR001W intact:EBI-2060312|uniprotkb:D3DKP5|ensemblfungi:YHL016C psi-mi:osh7_yeast(display_long)|uniprotkb:YHR001W(locus name)|uniprotkb:OSH7(gene name)|psi-mi:OSH7(display_short) psi-mi:dur3_yeast(display_long)|uniprotkb:DUR3(gene name)|psi-mi:DUR3(display_short)|uniprotkb:YHL016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329046|imex:IM-14275-1375 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR001W(gene)|ensemblfungi:YHR001W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_011863.1|sgd:S000001043|mint:P38755|dip:DIP-6363N interpro:IPR031155|refseq:NP_011847.1|sgd:S000001008|interpro:IPR001734(Na+/solute symporter)|interpro:IPR038377|mint:P33413|ensemblfungi:YHL016C(gene)|ensemblfungi:YHL016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0015204"(urea transmembrane transporter activity)|go:"GO:0015489"(putrescine transmembrane transporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015840"(urea transport)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) crc64:1C972ED6517D529B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CnsyJOWY7SpdJZ6GeUshxYiBNJk559292 rogid:oTFsdtOngA3q5wCbhK/fpVlIsz0559292 intact-crc:72F67AAAF528DC4E|rigid:wYkWoYCFACBqpZdRDOdRt85Pm54 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38755 uniprotkb:P36027 intact:EBI-12641|uniprotkb:D3DKR7|ensemblfungi:YHR001W intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:osh7_yeast(display_long)|uniprotkb:YHR001W(locus name)|uniprotkb:OSH7(gene name)|psi-mi:OSH7(display_short) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329057|imex:IM-14275-1376 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR001W(gene)|ensemblfungi:YHR001W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_011863.1|sgd:S000001043|mint:P38755|dip:DIP-6363N ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) crc64:1C972ED6517D529B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CnsyJOWY7SpdJZ6GeUshxYiBNJk559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:56EDAC5D0D1BD440|rigid:CoLxsfJ7rR/K+7Rc2tHebLTtXYc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38755 uniprotkb:P50276 intact:EBI-12641|uniprotkb:D3DKR7|ensemblfungi:YHR001W intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:osh7_yeast(display_long)|uniprotkb:YHR001W(locus name)|uniprotkb:OSH7(gene name)|psi-mi:OSH7(display_short) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329068|imex:IM-14275-1377 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR001W(gene)|ensemblfungi:YHR001W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_011863.1|sgd:S000001043|mint:P38755|dip:DIP-6363N ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) crc64:1C972ED6517D529B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CnsyJOWY7SpdJZ6GeUshxYiBNJk559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:FB8D2E197A8E0314|rigid:gKKVORsdfPPCslK33ZSdKHqjgQI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53049 uniprotkb:P38755 intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W intact:EBI-12641|uniprotkb:D3DKR7|ensemblfungi:YHR001W psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:osh7_yeast(display_long)|uniprotkb:YHR001W(locus name)|uniprotkb:OSH7(gene name)|psi-mi:OSH7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329079|imex:IM-14275-1378 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 ensemblfungi:YHR001W(gene)|ensemblfungi:YHR001W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_011863.1|sgd:S000001043|mint:P38755|dip:DIP-6363N psi-mi:"MI:0469"(intact) - crc64:1C972ED6517D529B figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 rogid:CnsyJOWY7SpdJZ6GeUshxYiBNJk559292 intact-crc:D5EB13851BDE5779|rigid:Cm+jv9NnICa42uS7vqKoNkjumiw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53832 uniprotkb:P38755 intact:EBI-2055941|uniprotkb:D6W0R1|ensemblfungi:YNL283C intact:EBI-12641|uniprotkb:D3DKR7|ensemblfungi:YHR001W psi-mi:wsc2_yeast(display_long)|uniprotkb:YNL283C(locus name)|uniprotkb:N0583(orf name)|uniprotkb:WSC2(gene name)|psi-mi:WSC2(display_short) psi-mi:osh7_yeast(display_long)|uniprotkb:YHR001W(locus name)|uniprotkb:OSH7(gene name)|psi-mi:OSH7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329090|imex:IM-14275-1379 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014116.1|sgd:S000005227|interpro:IPR002889(Carbohydrate-binding WSC)|mint:P53832|ensemblfungi:YNL283C(gene)|ensemblfungi:YNL283C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip) ensemblfungi:YHR001W(gene)|ensemblfungi:YHR001W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_011863.1|sgd:S000001043|mint:P38755|dip:DIP-6363N psi-mi:"MI:0469"(intact) - crc64:1C972ED6517D529B figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5wadvTv6SxcIAb60yfnuGMfa8pY559292 rogid:CnsyJOWY7SpdJZ6GeUshxYiBNJk559292 intact-crc:54FFE527F1A8A51A|rigid:G041/8kYT6HYkdyorRwMdEmGWtg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02201 uniprotkb:P38755 intact:EBI-12636|uniprotkb:D6VXT9|ensemblfungi:YKR003W intact:EBI-12641|uniprotkb:D3DKR7|ensemblfungi:YHR001W psi-mi:osh6_yeast(display_long)|uniprotkb:YK102(orf name)|uniprotkb:YKR003W(locus name)|uniprotkb:OSH6(gene name)|psi-mi:OSH6(display_short) psi-mi:osh7_yeast(display_long)|uniprotkb:YHR001W(locus name)|uniprotkb:OSH7(gene name)|psi-mi:OSH7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329101|imex:IM-14275-1380 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0015914"(phospholipid transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0120015"(sterol transfer activity)|rcsb pdb:4B2Z|rcsb pdb:4PH7|reactome:R-SCE-1482801|reactome:R-SCE-192105|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensemblfungi:YKR003W(gene)|ensemblfungi:YKR003W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|refseq:NP_012928.1|sgd:S000001711|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|mint:Q02201 ensemblfungi:YHR001W(gene)|ensemblfungi:YHR001W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_011863.1|sgd:S000001043|mint:P38755|dip:DIP-6363N psi-mi:"MI:0469"(intact) - crc64:1C972ED6517D529B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aOZdSdLn96ns0C9w9E3r62iNyYo559292 rogid:CnsyJOWY7SpdJZ6GeUshxYiBNJk559292 intact-crc:E9823FCE73AE87DF|rigid:wCMg5liTIRV0d/oNIgl7oivu7KM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02785 uniprotkb:P38755 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C intact:EBI-12641|uniprotkb:D3DKR7|ensemblfungi:YHR001W psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:osh7_yeast(display_long)|uniprotkb:YHR001W(locus name)|uniprotkb:OSH7(gene name)|psi-mi:OSH7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329112|imex:IM-14275-1381 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) ensemblfungi:YHR001W(gene)|ensemblfungi:YHR001W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_011863.1|sgd:S000001043|mint:P38755|dip:DIP-6363N psi-mi:"MI:0469"(intact) - crc64:1C972ED6517D529B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 rogid:CnsyJOWY7SpdJZ6GeUshxYiBNJk559292 intact-crc:9F8FFA52F2EEEE5B|rigid:Lwm7DXVq+XdG1OH+/8rwqCp2SUE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:P38755 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-12641|uniprotkb:D3DKR7|ensemblfungi:YHR001W psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:osh7_yeast(display_long)|uniprotkb:YHR001W(locus name)|uniprotkb:OSH7(gene name)|psi-mi:OSH7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329123|imex:IM-14275-1382 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 ensemblfungi:YHR001W(gene)|ensemblfungi:YHR001W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_011863.1|sgd:S000001043|mint:P38755|dip:DIP-6363N psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 crc64:1C972ED6517D529B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:CnsyJOWY7SpdJZ6GeUshxYiBNJk559292 intact-crc:D1BFFF7F5B5EB906|rigid:Y/UIaUnJnT7l4R5BFzFWcRSFUYE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08967 uniprotkb:P38755 intact:EBI-36673|uniprotkb:D6W3E9|ensemblfungi:YPL221W intact:EBI-12641|uniprotkb:D3DKR7|ensemblfungi:YHR001W psi-mi:flc1_yeast(display_long)|uniprotkb:FAD transporter 1(gene name synonym)|uniprotkb:FLC1(gene name)|psi-mi:FLC1(display_short)|uniprotkb:TRP-like ion channel protein FLC1(gene name synonym)|uniprotkb:Heme utilization factor 1(gene name synonym)|uniprotkb:Bypass of PAM1 protein 1(gene name synonym)|uniprotkb:HUF1(gene name synonym)|uniprotkb:YPL221W(locus name)|uniprotkb:BOP1(gene name synonym) psi-mi:osh7_yeast(display_long)|uniprotkb:YHR001W(locus name)|uniprotkb:OSH7(gene name)|psi-mi:OSH7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329134|imex:IM-14275-1383 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015103.1|sgd:S000006142|mint:Q08967|dip:DIP-3965N|ensemblfungi:YPL221W(gene)|ensemblfungi:YPL221W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055085"(transmembrane transport)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241 ensemblfungi:YHR001W(gene)|ensemblfungi:YHR001W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_011863.1|sgd:S000001043|mint:P38755|dip:DIP-6363N psi-mi:"MI:0469"(intact) - crc64:1C972ED6517D529B figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:r6CcZGEjxHUk2w0iBUBvnAPaFd4559292 rogid:CnsyJOWY7SpdJZ6GeUshxYiBNJk559292 intact-crc:262FD4B1855F473A|rigid:iEuumUWVz1O5zEIuSyyqjTYmzi8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38755 uniprotkb:Q12256 intact:EBI-12641|uniprotkb:D3DKR7|ensemblfungi:YHR001W intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C psi-mi:osh7_yeast(display_long)|uniprotkb:YHR001W(locus name)|uniprotkb:OSH7(gene name)|psi-mi:OSH7(display_short) psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329145|imex:IM-14275-1384 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR001W(gene)|ensemblfungi:YHR001W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_011863.1|sgd:S000001043|mint:P38755|dip:DIP-6363N refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:1C972ED6517D529B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CnsyJOWY7SpdJZ6GeUshxYiBNJk559292 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 intact-crc:6263EC4A6B683270|rigid:nqFFey+yd99eiwJVlCZNKAeRZVQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38755 uniprotkb:Q12335 intact:EBI-12641|uniprotkb:D3DKR7|ensemblfungi:YHR001W intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:osh7_yeast(display_long)|uniprotkb:YHR001W(locus name)|uniprotkb:OSH7(gene name)|psi-mi:OSH7(display_short) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329156|imex:IM-14275-1385 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR001W(gene)|ensemblfungi:YHR001W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_011863.1|sgd:S000001043|mint:P38755|dip:DIP-6363N refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) crc64:1C972ED6517D529B crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CnsyJOWY7SpdJZ6GeUshxYiBNJk559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:9A3838A3DA8ECCBC|rigid:9cceGKTQNFnhodARYdgTlqGo8xw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38759 uniprotkb:P32913 intact:EBI-13092|uniprotkb:D3DKV7|ensemblfungi:YHR012W intact:EBI-20366|uniprotkb:Q12279|uniprotkb:D6W2J0|ensemblfungi:YOR132W psi-mi:vps29_yeast(display_long)|uniprotkb:VPS29(gene name)|psi-mi:VPS29(display_short)|uniprotkb:PEP11(gene name synonym)|uniprotkb:Vesicle protein sorting 29(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 11(gene name synonym)|uniprotkb:VTP6(gene name synonym)|uniprotkb:YHR012W(locus name) psi-mi:vps17_yeast(display_long)|uniprotkb:VPS17(gene name)|psi-mi:VPS17(display_short)|uniprotkb:PEP21(gene name synonym)|uniprotkb:YOR132W(locus name)|uniprotkb:O3314(orf name)|uniprotkb:YOR3314W(orf name)|uniprotkb:Carboxypeptidase Y-deficient protein 21(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329167|imex:IM-14275-1386 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011876.1|sgd:S000001054|mint:P38759|dip:DIP-4205N|ensemblfungi:YHR012W(gene)|ensemblfungi:YHR012W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|reactome:R-SCE-3238698 sgd:S000005658|refseq:NP_014775.3|ensemblfungi:YOR132W(gene)|ensemblfungi:YOR132W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR001683(Phox-like)|interpro:IPR014461(Vacuolar protein sorting-associated protein Vps17)|interpro:IPR027267|interpro:IPR036871|interpro:IPR037907|dip:DIP-1739N|mint:P32913 psi-mi:"MI:0469"(intact) crc64:D190DBA2377E0653 crc64:C709968468144A50 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3oTN5S2STdiGgFHUVKYWifCVgi4559292 rogid:X5nNIyX3T0PYprdyJaxVnc8RoR8559292 intact-crc:5E0D0D624D68F054|rigid:Mq9ALpNzMOhHl5THMjdhnZOMXGI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34110 uniprotkb:P38759 intact:EBI-20415|uniprotkb:D6VW33|ensemblfungi:YJL154C intact:EBI-13092|uniprotkb:D3DKV7|ensemblfungi:YHR012W psi-mi:vps35_yeast(display_long)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:Vacuolar protein-targeting protein 7(gene name synonym)|uniprotkb:VPT7(gene name synonym)|uniprotkb:J0580(orf name)|uniprotkb:YJL154C(locus name) psi-mi:vps29_yeast(display_long)|uniprotkb:VPS29(gene name)|psi-mi:VPS29(display_short)|uniprotkb:PEP11(gene name synonym)|uniprotkb:Vesicle protein sorting 29(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 11(gene name synonym)|uniprotkb:VTP6(gene name synonym)|uniprotkb:YHR012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329178|imex:IM-14275-1387 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012381.1|sgd:S000003690|ensemblfungi:YJL154C(gene)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1904377"(positive regulation of protein localization to cell periphery)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR042491|reactome:R-SCE-3238698|ensemblfungi:YJL154C_mRNA(transcript)|dip:DIP-1743N|mint:P34110 refseq:NP_011876.1|sgd:S000001054|mint:P38759|dip:DIP-4205N|ensemblfungi:YHR012W(gene)|ensemblfungi:YHR012W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|reactome:R-SCE-3238698 psi-mi:"MI:0469"(intact) crc64:DE1BC57B9DFB606E crc64:D190DBA2377E0653 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5KBi/lSF+BsMyg9ulP9eLCp2xCc559292 rogid:3oTN5S2STdiGgFHUVKYWifCVgi4559292 intact-crc:F67066298AC7A8D1|rigid:unro9m314IQbx+sFx1jSBNueI1c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38759 uniprotkb:P38759 intact:EBI-13092|uniprotkb:D3DKV7|ensemblfungi:YHR012W intact:EBI-13092|uniprotkb:D3DKV7|ensemblfungi:YHR012W psi-mi:vps29_yeast(display_long)|uniprotkb:VPS29(gene name)|psi-mi:VPS29(display_short)|uniprotkb:PEP11(gene name synonym)|uniprotkb:Vesicle protein sorting 29(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 11(gene name synonym)|uniprotkb:VTP6(gene name synonym)|uniprotkb:YHR012W(locus name) psi-mi:vps29_yeast(display_long)|uniprotkb:VPS29(gene name)|psi-mi:VPS29(display_short)|uniprotkb:PEP11(gene name synonym)|uniprotkb:Vesicle protein sorting 29(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 11(gene name synonym)|uniprotkb:VTP6(gene name synonym)|uniprotkb:YHR012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329189|imex:IM-14275-1388 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011876.1|sgd:S000001054|mint:P38759|dip:DIP-4205N|ensemblfungi:YHR012W(gene)|ensemblfungi:YHR012W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|reactome:R-SCE-3238698 refseq:NP_011876.1|sgd:S000001054|mint:P38759|dip:DIP-4205N|ensemblfungi:YHR012W(gene)|ensemblfungi:YHR012W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|reactome:R-SCE-3238698 psi-mi:"MI:0469"(intact) crc64:D190DBA2377E0653 crc64:D190DBA2377E0653 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3oTN5S2STdiGgFHUVKYWifCVgi4559292 rogid:3oTN5S2STdiGgFHUVKYWifCVgi4559292 intact-crc:3D5A1CBCD0F19867|rigid:A6BBwZOq7xUP5MZNY2bjYI4QIXs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38759 uniprotkb:Q92331 intact:EBI-13092|uniprotkb:D3DKV7|ensemblfungi:YHR012W intact:EBI-20483|uniprotkb:Q08483|uniprotkb:D6W2D1|uniprotkb:E9P8U6|ensemblfungi:YOR069W psi-mi:vps29_yeast(display_long)|uniprotkb:VPS29(gene name)|psi-mi:VPS29(display_short)|uniprotkb:PEP11(gene name synonym)|uniprotkb:Vesicle protein sorting 29(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 11(gene name synonym)|uniprotkb:VTP6(gene name synonym)|uniprotkb:YHR012W(locus name) psi-mi:vps5_yeast(display_long)|uniprotkb:VPS5(gene name)|psi-mi:VPS5(display_short)|uniprotkb:GRD2(gene name synonym)|uniprotkb:PEP10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 5(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 10(gene name synonym)|uniprotkb:VPT5(gene name synonym)|uniprotkb:YOR29-20(orf name)|uniprotkb:YOR069W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329200|imex:IM-14275-1389 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011876.1|sgd:S000001054|mint:P38759|dip:DIP-4205N|ensemblfungi:YHR012W(gene)|ensemblfungi:YHR012W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|reactome:R-SCE-3238698 refseq:NP_014712.2|sgd:S000005595|ensemblfungi:YOR069W(gene)|ensemblfungi:YOR069W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0005768"(endosome)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|interpro:IPR001683(Phox-like)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028648|interpro:IPR035803|interpro:IPR036871|interpro:IPR037868|dip:DIP-1740N|mint:Q92331 psi-mi:"MI:0469"(intact) crc64:D190DBA2377E0653 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3oTN5S2STdiGgFHUVKYWifCVgi4559292 rogid:5aPSkQUJV1sfIc9Ql+wMP74Y3QI559292 intact-crc:07A1EE86AEBD4FC6|rigid:UH0bWuu76qKpIkJIBunuuHpbNH4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33297 uniprotkb:P38764 intact:EBI-13920|uniprotkb:D6W2H6|ensemblfungi:YOR117W intact:EBI-15913|uniprotkb:D3DKX4|ensemblfungi:YHR027C psi-mi:prs6a_yeast(display_long)|uniprotkb:RPT5(gene name)|psi-mi:RPT5(display_short)|uniprotkb:YTA1(gene name synonym)|uniprotkb:YOR117W(locus name)|uniprotkb:O3258(orf name)|uniprotkb:YOR3258W(orf name)|uniprotkb:Tat-binding protein homolog 1(gene name synonym) psi-mi:rpn1_yeast(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:HRD2(gene name synonym)|uniprotkb:NAS1(gene name synonym)|uniprotkb:RPD1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 1(gene name synonym)|uniprotkb:HMG-CoA reductase degradation protein 2(gene name synonym)|uniprotkb:YHR027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329211|imex:IM-14275-1390 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005643|rcsb pdb:3WHL|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|rcsb pdb:3WHK|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|ensemblfungi:YOR117W(gene)|ensemblfungi:YOR117W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|refseq:NP_014760.3|mint:P33297|dip:DIP-1590N refseq:NP_011892.1|sgd:S000001069|ensemblfungi:YHR027C(gene)|ensemblfungi:YHR027C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|rcsb pdb:2N3T|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBW|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|rcsb pdb:6FVU|reactome:R-SCE-983168|rcsb pdb:6FVV|rcsb pdb:6FVW|dip:DIP-2876N|mint:P38764 psi-mi:"MI:0469"(intact) crc64:C215422033FCE830 crc64:B77954F4A998BA7C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jsQE3SjBA0ZZcysuLgFe/5M6pOc559292 rogid:KZvwC6NNLC/jEW8wXPq2z+EFukY559292 intact-crc:17C4FC836AA4BC27|rigid:yu3pNpqPTeME6ojbWEFLQWnzkjk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33299 uniprotkb:P38764 intact:EBI-13910|uniprotkb:D6VX51|ensemblfungi:YKL145W intact:EBI-15913|uniprotkb:D3DKX4|ensemblfungi:YHR027C psi-mi:prs7_yeast(display_long)|uniprotkb:YKL145W(locus name)|uniprotkb:RPT1(gene name)|psi-mi:RPT1(display_short)|uniprotkb:CIM5(gene name synonym)|uniprotkb:YTA3(gene name synonym)|uniprotkb:Protein CIM5(gene name synonym)|uniprotkb:Tat-binding homolog 3(gene name synonym) psi-mi:rpn1_yeast(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:HRD2(gene name synonym)|uniprotkb:NAS1(gene name synonym)|uniprotkb:RPD1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 1(gene name synonym)|uniprotkb:HMG-CoA reductase degradation protein 2(gene name synonym)|uniprotkb:YHR027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329222|imex:IM-14275-1391 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012777.1|sgd:S000001628|ensemblfungi:YKL145W(gene)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|ensemblfungi:YKL145W_mRNA(transcript)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0005524"(ATP binding)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|go:"GO:0005634"(nucleus)|rcsb pdb:3VLF|rcsb pdb:4A3V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4JPO|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|rcsb pdb:5A5B|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:5MP9|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|rcsb pdb:6EF3|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33299|dip:DIP-2883N refseq:NP_011892.1|sgd:S000001069|ensemblfungi:YHR027C(gene)|ensemblfungi:YHR027C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|rcsb pdb:2N3T|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBW|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|rcsb pdb:6FVU|reactome:R-SCE-983168|rcsb pdb:6FVV|rcsb pdb:6FVW|dip:DIP-2876N|mint:P38764 psi-mi:"MI:0469"(intact) crc64:8454BBC9D549EC5C crc64:B77954F4A998BA7C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8XXo53yZ1KevHObtYWABeFr0hWo559292 rogid:KZvwC6NNLC/jEW8wXPq2z+EFukY559292 intact-crc:19C4FCBD0E7D2FBB|rigid:IctTINCRjGZ3Y9UudyIR3e9l0lc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38764 uniprotkb:P40327 intact:EBI-15913|uniprotkb:D3DKX4|ensemblfungi:YHR027C intact:EBI-13901|uniprotkb:D6VRY1|ensemblfungi:YDL007W psi-mi:rpn1_yeast(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:HRD2(gene name synonym)|uniprotkb:NAS1(gene name synonym)|uniprotkb:RPD1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 1(gene name synonym)|uniprotkb:HMG-CoA reductase degradation protein 2(gene name synonym)|uniprotkb:YHR027C(locus name) psi-mi:prs4_yeast(display_long)|uniprotkb:RPT2(gene name)|psi-mi:RPT2(display_short)|uniprotkb:YHS4(gene name synonym)|uniprotkb:YTA5(gene name synonym)|uniprotkb:YDL007W(locus name)|uniprotkb:D2920(orf name)|uniprotkb:Tat-binding homolog 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329233|imex:IM-14275-1392 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011892.1|sgd:S000001069|ensemblfungi:YHR027C(gene)|ensemblfungi:YHR027C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|rcsb pdb:2N3T|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBW|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|rcsb pdb:6FVU|reactome:R-SCE-983168|rcsb pdb:6FVV|rcsb pdb:6FVW|dip:DIP-2876N|mint:P38764 refseq:NP_010277.1|sgd:S000002165|ensemblfungi:YDL007W(gene)|ensemblfungi:YDL007W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0034629"|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:4CR2|rcsb pdb:3JCP|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-532668|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P40327|dip:DIP-6282N psi-mi:"MI:0469"(intact) crc64:B77954F4A998BA7C crc64:EB735354C3A0EBD4 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:KZvwC6NNLC/jEW8wXPq2z+EFukY559292 rogid:nSy31Q+snoZMZrFmXscv8/HQYk0559292 intact-crc:9E0898F405E9445F|rigid:EpsbvEN09ydGevg6c13ny291oc0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03940 uniprotkb:P38768 intact:EBI-30712|uniprotkb:D6VSH3|ensemblfungi:YDR190C intact:EBI-24499|uniprotkb:D3DKY1|ensemblfungi:YHR034C psi-mi:ruvb1_yeast(display_long)|uniprotkb:RVB1(gene name)|psi-mi:RVB1(display_short)|uniprotkb:TIP49-homology protein 1(gene name synonym)|uniprotkb:TIP49a homolog(gene name synonym)|uniprotkb:TIH1(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:YDR190C(locus name) psi-mi:pih1_yeast(display_long)|uniprotkb:PIH1(gene name)|psi-mi:PIH1(display_short)|uniprotkb:NOP17(gene name synonym)|uniprotkb:Nucleolar protein 17(gene name synonym)|uniprotkb:YHR034C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329244|imex:IM-14275-1393 author score:99.24 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010476.1|sgd:S000002598|dip:DIP-4896N|mint:Q03940|ensemblfungi:YDR190C(gene)|ensemblfungi:YDR190C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043486"(histone exchange)|go:"GO:0070209"(ASTRA complex)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|rcsb pdb:6GEJ|rcsb pdb:6GEN|reactome:R-SCE-5689880 refseq:NP_011899.1|sgd:S000001076|dip:DIP-807N|mint:P38768|ensemblfungi:YHR034C(gene)|ensemblfungi:YHR034C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008380"(RNA splicing)|go:"GO:0097255"(R2TP complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR012981(Nop17p)|interpro:IPR041441|rcsb pdb:2MNJ|rcsb pdb:4CGU|rcsb pdb:4CHH psi-mi:"MI:0469"(intact) crc64:93D6ECB7006AF0F2 crc64:02C06D0A113B1B3B figure legend:tables S3 and S4|author-confidence:99.24|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tVQiqr2rPrfXb1Wb/2XUOTBBXIQ559292 rogid:5z/tmH0iorWwa2yX80ZUuQAZEQw559292 intact-crc:3B265FCB9D09DE9B|rigid:lwmdz7iQ5sC6UDYFSHwRaLTd98A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38779 uniprotkb:P21304 intact:EBI-24538|uniprotkb:D3DL01|ensemblfungi:YHR052W intact:EBI-14328|uniprotkb:D6VYJ9|ensemblfungi:YLR196W psi-mi:cic1_yeast(display_long)|uniprotkb:CIC1(gene name)|psi-mi:CIC1(display_short)|uniprotkb:NSA3(gene name synonym)|uniprotkb:Core interacting component 1(gene name synonym)|uniprotkb:YHR052W(locus name) psi-mi:pwp1_yeast(display_long)|uniprotkb:L8167.10(orf name)|uniprotkb:YLR196W(locus name)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329255|imex:IM-14275-1394 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011919.1|sgd:S000001094|dip:DIP-6491N|mint:P38779|ensemblfungi:YHR052W(gene)|ensemblfungi:YHR052W_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0019843"(rRNA binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0070628"(proteasome binding)|interpro:IPR023674|interpro:IPR028364|interpro:IPR028365|rcsb pdb:3JCT|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6M62|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BTB|go:"GO:0034513"(box H/ACA snoRNA binding) refseq:NP_013297.1|sgd:S000004186|ensemblfungi:YLR196W(gene)|ensemblfungi:YLR196W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR044285|mint:P21304|dip:DIP-4203N psi-mi:"MI:0469"(intact) crc64:13A2AFA0B927CD98 crc64:FC0189B289494AB5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rdhoaLdCr+bDCy9BYwEA9foQFWQ559292 rogid:Q1nPXtlkpIw8JosaiYX0PSVNaSw559292 intact-crc:67C87A2756DE3442|rigid:sIb4mZwA+G87PUHHAbaSHqvWbsk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38779 uniprotkb:P24783 intact:EBI-24538|uniprotkb:D3DL01|ensemblfungi:YHR052W intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W psi-mi:cic1_yeast(display_long)|uniprotkb:CIC1(gene name)|psi-mi:CIC1(display_short)|uniprotkb:NSA3(gene name synonym)|uniprotkb:Core interacting component 1(gene name synonym)|uniprotkb:YHR052W(locus name) psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329266|imex:IM-14275-1395 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011919.1|sgd:S000001094|dip:DIP-6491N|mint:P38779|ensemblfungi:YHR052W(gene)|ensemblfungi:YHR052W_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0019843"(rRNA binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0070628"(proteasome binding)|interpro:IPR023674|interpro:IPR028364|interpro:IPR028365|rcsb pdb:3JCT|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6M62|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BTB|go:"GO:0034513"(box H/ACA snoRNA binding) sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) crc64:13A2AFA0B927CD98 crc64:30FE3D4C7E653120 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rdhoaLdCr+bDCy9BYwEA9foQFWQ559292 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 intact-crc:EA78ACDD414BD2E0|rigid:uQlQJD+pWJeISRnV7Czxv5n6Z8A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38779 uniprotkb:P38779 intact:EBI-24538|uniprotkb:D3DL01|ensemblfungi:YHR052W intact:EBI-24538|uniprotkb:D3DL01|ensemblfungi:YHR052W psi-mi:cic1_yeast(display_long)|uniprotkb:CIC1(gene name)|psi-mi:CIC1(display_short)|uniprotkb:NSA3(gene name synonym)|uniprotkb:Core interacting component 1(gene name synonym)|uniprotkb:YHR052W(locus name) psi-mi:cic1_yeast(display_long)|uniprotkb:CIC1(gene name)|psi-mi:CIC1(display_short)|uniprotkb:NSA3(gene name synonym)|uniprotkb:Core interacting component 1(gene name synonym)|uniprotkb:YHR052W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329277|imex:IM-14275-1396 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011919.1|sgd:S000001094|dip:DIP-6491N|mint:P38779|ensemblfungi:YHR052W(gene)|ensemblfungi:YHR052W_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0019843"(rRNA binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0070628"(proteasome binding)|interpro:IPR023674|interpro:IPR028364|interpro:IPR028365|rcsb pdb:3JCT|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6M62|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BTB|go:"GO:0034513"(box H/ACA snoRNA binding) refseq:NP_011919.1|sgd:S000001094|dip:DIP-6491N|mint:P38779|ensemblfungi:YHR052W(gene)|ensemblfungi:YHR052W_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0019843"(rRNA binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0070628"(proteasome binding)|interpro:IPR023674|interpro:IPR028364|interpro:IPR028365|rcsb pdb:3JCT|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6M62|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BTB|go:"GO:0034513"(box H/ACA snoRNA binding) psi-mi:"MI:0469"(intact) crc64:13A2AFA0B927CD98 crc64:13A2AFA0B927CD98 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rdhoaLdCr+bDCy9BYwEA9foQFWQ559292 rogid:rdhoaLdCr+bDCy9BYwEA9foQFWQ559292 intact-crc:01276EAA95C083EB|rigid:p1x6oE/gSGb8rMNzFPWd2Ik923I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53874 uniprotkb:P38779 intact:EBI-19873|uniprotkb:D6W101|ensemblfungi:YNL186W intact:EBI-24538|uniprotkb:D3DL01|ensemblfungi:YHR052W psi-mi:ubp10_yeast(display_long)|uniprotkb:UBP10(gene name)|psi-mi:UBP10(display_short)|uniprotkb:YNL186W(locus name)|uniprotkb:N1619(orf name)|uniprotkb:Ubiquitin-specific-processing protease 10(gene name synonym)|uniprotkb:Deubiquitinating enzyme 10(gene name synonym)|uniprotkb:Disrupter of telomere silencing protein 4(gene name synonym)|uniprotkb:Ubiquitin thioesterase 10(gene name synonym)|uniprotkb:DOT4(gene name synonym) psi-mi:cic1_yeast(display_long)|uniprotkb:CIC1(gene name)|psi-mi:CIC1(display_short)|uniprotkb:NSA3(gene name synonym)|uniprotkb:Core interacting component 1(gene name synonym)|uniprotkb:YHR052W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329288|imex:IM-14275-1397 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014213.2|sgd:S000005130|ensemblfungi:YNL186W(gene)|ensemblfungi:YNL186W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0043596"(nuclear replication fork)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|rcsb pdb:6RR0|dip:DIP-6664N|mint:P53874 refseq:NP_011919.1|sgd:S000001094|dip:DIP-6491N|mint:P38779|ensemblfungi:YHR052W(gene)|ensemblfungi:YHR052W_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0019843"(rRNA binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0070628"(proteasome binding)|interpro:IPR023674|interpro:IPR028364|interpro:IPR028365|rcsb pdb:3JCT|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6M62|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BTB|go:"GO:0034513"(box H/ACA snoRNA binding) psi-mi:"MI:0469"(intact) - crc64:13A2AFA0B927CD98 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Z1rRAI9RLgHeGd7QwLbrf51v5LY559292 rogid:rdhoaLdCr+bDCy9BYwEA9foQFWQ559292 intact-crc:D2D48938A256E1B1|rigid:06vAQaSbNICyrNwVJtDzrL54im0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38784 uniprotkb:P35180 intact:EBI-20329|uniprotkb:D3DL09|ensemblfungi:YHR060W intact:EBI-12522|uniprotkb:D6VUL4|ensemblfungi:YGR082W psi-mi:vma22_yeast(display_long)|uniprotkb:VMA22(gene name)|psi-mi:VMA22(display_short)|uniprotkb:YHR060W(locus name) psi-mi:tom20_yeast(display_long)|uniprotkb:MOM19(gene name synonym)|uniprotkb:YGR082W(locus name)|uniprotkb:TOM20(gene name)|psi-mi:TOM20(display_short)|uniprotkb:MAS20(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 20 kDa subunit(gene name synonym)|uniprotkb:Protein MAS20(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329299|imex:IM-14275-1398 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001102|refseq:NP_011927.1|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|go:"GO:1990871"(Vma12-Vma22 assembly complex)|interpro:IPR040357|ensemblfungi:YHR060W(gene)|ensemblfungi:YHR060W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|dip:DIP-1736N|mint:P38784 ensemblfungi:YGR082W(gene)|ensemblfungi:YGR082W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR023392|refseq:NP_011596.1|sgd:S000003314|dip:DIP-2539N|mint:P35180 psi-mi:"MI:0469"(intact) crc64:C1CB5DC8292D2734 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lsyg/iwoAn23drBc+mamX2nPOv4559292 rogid:7U00YLVWcaegWlJEKzGblv6STx4559292 intact-crc:FDAE62B9B98B4B43|rigid:HeEUOc4tL/14yekm27iLmjaxXqk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38784 uniprotkb:Q03768 intact:EBI-20329|uniprotkb:D3DL09|ensemblfungi:YHR060W intact:EBI-7618|uniprotkb:D6VSD4|ensemblfungi:YDR152W psi-mi:vma22_yeast(display_long)|uniprotkb:VMA22(gene name)|psi-mi:VMA22(display_short)|uniprotkb:YHR060W(locus name) psi-mi:gir2_yeast(display_long)|uniprotkb:GIR2(gene name)|psi-mi:GIR2(display_short)|uniprotkb:YDR152W(locus name)|uniprotkb:YD8358.08(orf name)|uniprotkb:DFRP2(gene name synonym)|uniprotkb:DRG family-regulatory protein 2(gene name synonym)|uniprotkb:Genetically interacts with ribosomal genes protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329310|imex:IM-14275-1399 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001102|refseq:NP_011927.1|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|go:"GO:1990871"(Vma12-Vma22 assembly complex)|interpro:IPR040357|ensemblfungi:YHR060W(gene)|ensemblfungi:YHR060W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|dip:DIP-1736N|mint:P38784 sgd:S000002559|refseq:NP_010436.3|mint:Q03768|dip:DIP-1751N|ensemblfungi:YDR152W(gene)|ensemblfungi:YDR152W_mRNA(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR006575(RWD)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR040213 psi-mi:"MI:0469"(intact) crc64:C1CB5DC8292D2734 crc64:CE09A067388638ED figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lsyg/iwoAn23drBc+mamX2nPOv4559292 rogid:2gb8Bf2IGl8RoOmNcIvEMlmgeTE559292 intact-crc:D973FFF5BCFB4D90|rigid:xHETFBnPm8F2zkm2KU05VSMB3/k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38787 uniprotkb:P38787 intact:EBI-12913|uniprotkb:D3DL12|ensemblfungi:YHR063C intact:EBI-12913|uniprotkb:D3DL12|ensemblfungi:YHR063C psi-mi:pane_yeast(display_long)|uniprotkb:YHR063C(locus name)|uniprotkb:PAN5(gene name)|psi-mi:PAN5(display_short)|uniprotkb:Ketopantoate reductase(gene name synonym) psi-mi:pane_yeast(display_long)|uniprotkb:YHR063C(locus name)|uniprotkb:PAN5(gene name)|psi-mi:PAN5(display_short)|uniprotkb:Ketopantoate reductase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329321|imex:IM-14275-1400 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011930.1|sgd:S000001105|ensemblfungi:YHR063C(gene)|ensemblfungi:YHR063C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008677"(2-dehydropantoate 2-reductase activity)|go:"GO:0015940"(pantothenate biosynthetic process)|go:"GO:0050661"(NADP binding)|interpro:IPR003710(Ketopantoate reductase ApbA/PanE)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR013332(Ketopantoate reductase ApbA/PanE, N-terminal)|interpro:IPR013752(Ketopantoate reductase ApbA/PanE, C-terminal)|interpro:IPR036291|mint:P38787|dip:DIP-5591N refseq:NP_011930.1|sgd:S000001105|ensemblfungi:YHR063C(gene)|ensemblfungi:YHR063C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008677"(2-dehydropantoate 2-reductase activity)|go:"GO:0015940"(pantothenate biosynthetic process)|go:"GO:0050661"(NADP binding)|interpro:IPR003710(Ketopantoate reductase ApbA/PanE)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR013332(Ketopantoate reductase ApbA/PanE, N-terminal)|interpro:IPR013752(Ketopantoate reductase ApbA/PanE, C-terminal)|interpro:IPR036291|mint:P38787|dip:DIP-5591N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ppp+rFeMgh+E/8WIRLrqgxYKn2Y559292 rogid:Ppp+rFeMgh+E/8WIRLrqgxYKn2Y559292 intact-crc:6835EA19FB8DE848|rigid:SqqfUO8H+lYyFHdkHyPz2JBBWt8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38791 uniprotkb:Q06836 intact:EBI-5871|uniprotkb:D3DL17|ensemblfungi:YHR068W intact:EBI-2054630|uniprotkb:D6W494|ensemblfungi:YPR095C psi-mi:dhys_yeast(display_long)|uniprotkb:YHR068W(locus name)|uniprotkb:DYS1(gene name)|psi-mi:DYS1(display_short) psi-mi:syt1_yeast(display_long)|uniprotkb:Suppressor of YPT3 protein 1(gene name synonym)|uniprotkb:P9513.17(orf name)|uniprotkb:YPR095C(locus name)|uniprotkb:SYT1(gene name)|psi-mi:SYT1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329332|imex:IM-14275-1401 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011935.1|sgd:S000001110|dip:DIP-2788N|mint:P38791|ensemblfungi:YHR068W(gene)|ensemblfungi:YHR068W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008612"(peptidyl-lysine modification to peptidyl-hypusine)|go:"GO:0034038"(deoxyhypusine synthase activity)|interpro:IPR002773(Deoxyhypusine synthase)|interpro:IPR029035|interpro:IPR036982|reactome:R-SCE-204626 refseq:NP_015420.1|sgd:S000006299|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000904(SEC7-like)|interpro:IPR023394|mint:Q06836|interpro:IPR035999|ensemblfungi:YPR095C(gene)|ensemblfungi:YPR095C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006887"(exocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032014"(positive regulation of ARF protein signal transduction)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|reactome:R-SCE-6811438 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nnqQ22LNFXyfdSqHeg3mu/iXPuI559292 rogid:C817mhl/RD3lHKZecr1dVzK6OJY559292 intact-crc:1C14C2F789A4B7E5|rigid:ASaQsnxHrCFW1HxDmMDWgB2MnA0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17883 uniprotkb:P38792 intact:EBI-1861|uniprotkb:Q06585|ensemblfungi:YPR189W intact:EBI-1757|uniprotkb:D3DL18|ensemblfungi:YHR069C psi-mi:ski3_yeast(display_long)|uniprotkb:SKI3(gene name)|psi-mi:SKI3(display_short)|uniprotkb:P9677.7(orf name)|uniprotkb:YPR189W(locus name) psi-mi:rrp4_yeast(display_long)|uniprotkb:RRP4(gene name)|psi-mi:RRP4(display_short)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:YHR069C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329343|imex:IM-14275-1402 author score:99.24 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006393|refseq:NP_015515.1|dip:DIP-6379N|mint:P17883|ensemblfungi:YPR189W(gene)|ensemblfungi:YPR189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039226|interpro:IPR040962|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958 refseq:NP_011936.1|sgd:S000001111|dip:DIP-5888N|mint:P38792|ensemblfungi:YHR069C(gene)|ensemblfungi:YHR069C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:18FFF78D7CA5A6E4 crc64:0718A7ABF42E9B9B figure legend:tables S3 and S4|author-confidence:99.24|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wjMKcbtN38crXFX7hQgZ0Bz475Y559292 rogid:ZgBS9xjR7jC96sAb0m63ElPvM7M559292 intact-crc:03736817463C8DE7|rigid:l9xx642ef2XHCPksBIFgAvj/E2U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38792 uniprotkb:Q02793 intact:EBI-1757|uniprotkb:D3DL18|ensemblfungi:YHR069C intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C psi-mi:rrp4_yeast(display_long)|uniprotkb:RRP4(gene name)|psi-mi:RRP4(display_short)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:YHR069C(locus name) psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329354|imex:IM-14275-1403 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011936.1|sgd:S000001111|dip:DIP-5888N|mint:P38792|ensemblfungi:YHR069C(gene)|ensemblfungi:YHR069C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793 psi-mi:"MI:0469"(intact) crc64:0718A7ABF42E9B9B crc64:C5E7B9D2268F9727 figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZgBS9xjR7jC96sAb0m63ElPvM7M559292 rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292 intact-crc:DECD0D820C303C92|rigid:sNuUmkh0fV33D5/ZgZPbJ+MkcHU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38795 uniprotkb:P38795 intact:EBI-11799|ensemblfungi:YHR074W|uniprotkb:D3DL24 intact:EBI-11799|ensemblfungi:YHR074W|uniprotkb:D3DL24 psi-mi:nade_yeast(display_long)|uniprotkb:QNS1(gene name)|psi-mi:QNS1(display_short)|uniprotkb:"NAD(+) synthase [glutamine-hydrolyzing]"(gene name synonym)|uniprotkb:YHR074W(locus name) psi-mi:nade_yeast(display_long)|uniprotkb:QNS1(gene name)|psi-mi:QNS1(display_short)|uniprotkb:"NAD(+) synthase [glutamine-hydrolyzing]"(gene name synonym)|uniprotkb:YHR074W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329365|imex:IM-14275-1404 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003694(NAD+ synthase)|interpro:IPR014445("Glutamine-dependent NAD(+) synthetase, GAT region")|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR022310|interpro:IPR036526|reactome:R-SCE-196807|ensemblfungi:YHR074W(gene)|ensemblfungi:YHR074W_mRNA(transcript)|go:"GO:0003952"("NAD+ synthase (glutamine-hydrolyzing) activity")|go:"GO:0004359"(glutaminase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009435"(NAD biosynthetic process)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|refseq:NP_011941.1|sgd:S000001116|dip:DIP-5592N|mint:P38795 interpro:IPR003694(NAD+ synthase)|interpro:IPR014445("Glutamine-dependent NAD(+) synthetase, GAT region")|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR022310|interpro:IPR036526|reactome:R-SCE-196807|ensemblfungi:YHR074W(gene)|ensemblfungi:YHR074W_mRNA(transcript)|go:"GO:0003952"("NAD+ synthase (glutamine-hydrolyzing) activity")|go:"GO:0004359"(glutaminase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009435"(NAD biosynthetic process)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|refseq:NP_011941.1|sgd:S000001116|dip:DIP-5592N|mint:P38795 psi-mi:"MI:0469"(intact) crc64:ED8C723550F9E8A9 crc64:ED8C723550F9E8A9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Vlj8G6/f0t/V+e1SPoDI/YhrnIM559292 rogid:Vlj8G6/f0t/V+e1SPoDI/YhrnIM559292 intact-crc:FB794557E80EE9A3|rigid:ioQ5glZOkyeRzPAXdHa9XEKaw10 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38810 uniprotkb:P38810 intact:EBI-17012|uniprotkb:D3DL48|ensemblfungi:YHR098C intact:EBI-17012|uniprotkb:D3DL48|ensemblfungi:YHR098C psi-mi:sfb3_yeast(display_long)|uniprotkb:SFB3(gene name)|psi-mi:SFB3(display_short)|uniprotkb:SEC24-related protein 3(gene name synonym)|uniprotkb:Lethal with SEC13 protein 1(gene name synonym)|uniprotkb:LST1(gene name synonym)|uniprotkb:YHR098C(locus name) psi-mi:sfb3_yeast(display_long)|uniprotkb:SFB3(gene name)|psi-mi:SFB3(display_short)|uniprotkb:SEC24-related protein 3(gene name synonym)|uniprotkb:Lethal with SEC13 protein 1(gene name synonym)|uniprotkb:LST1(gene name synonym)|uniprotkb:YHR098C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329376|imex:IM-14275-1405 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011966.1|sgd:S000001140|ensemblfungi:YHR098C(gene)|ensemblfungi:YHR098C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|interpro:IPR036174|go:"GO:0030127"(COPII vesicle coat)|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0043332"(mating projection tip)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071944"(cell periphery)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|dip:DIP-2949N|mint:P38810 refseq:NP_011966.1|sgd:S000001140|ensemblfungi:YHR098C(gene)|ensemblfungi:YHR098C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|interpro:IPR036174|go:"GO:0030127"(COPII vesicle coat)|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0043332"(mating projection tip)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071944"(cell periphery)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|dip:DIP-2949N|mint:P38810 psi-mi:"MI:0469"(intact) crc64:6A028AD6B1A2E031 crc64:6A028AD6B1A2E031 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+UqTvqDtF6TcA3pcbFJfvzKsoyc559292 rogid:+UqTvqDtF6TcA3pcbFJfvzKsoyc559292 intact-crc:671AE6416E895611|rigid:kFdgNjDjgukL4p0u9q9J7LgcT0I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38819 uniprotkb:P53337 intact:EBI-6603|uniprotkb:D3DL60|ensemblfungi:YHR110W intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C psi-mi:erp5_yeast(display_long)|uniprotkb:ERP5(gene name)|psi-mi:ERP5(display_short)|uniprotkb:YHR110W(locus name) psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329387|imex:IM-14275-1406 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011978.1|sgd:S000001152|mint:P38819|dip:DIP-7586N|ensemblfungi:YHR110W(gene)|ensemblfungi:YHR110W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dxo+Sd/z45fHXllQ80yOOxm19jE559292 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 intact-crc:70A9427D0B335F7A|rigid:gcouK1V1rDnlY7dDoF9STa9UJpE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:P38819 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-6603|uniprotkb:D3DL60|ensemblfungi:YHR110W psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:erp5_yeast(display_long)|uniprotkb:ERP5(gene name)|psi-mi:ERP5(display_short)|uniprotkb:YHR110W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329398|imex:IM-14275-1407 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_011978.1|sgd:S000001152|mint:P38819|dip:DIP-7586N|ensemblfungi:YHR110W(gene)|ensemblfungi:YHR110W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:dxo+Sd/z45fHXllQ80yOOxm19jE559292 intact-crc:D5ECE9E06059EC3D|rigid:R0NDwtkzeLK3HIvu2ueSVWIRtIc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38824 uniprotkb:P09959 intact:EBI-24690|uniprotkb:D3DL66|ensemblfungi:YHR116W intact:EBI-18641|uniprotkb:D6VYI6|ensemblfungi:YLR182W psi-mi:cox23_yeast(display_long)|uniprotkb:YHR116W(locus name)|uniprotkb:COX23(gene name)|psi-mi:COX23(display_short) psi-mi:swi6_yeast(display_long)|uniprotkb:SWI6(gene name)|psi-mi:SWI6(display_short)|uniprotkb:YLR182W(locus name)|uniprotkb:L9470.8(orf name)|uniprotkb:Cell-cycle box factor subunit SWI6(gene name synonym)|uniprotkb:Trans-acting activator of HO endonuclease gene(gene name synonym)|uniprotkb:MBF subunit P90(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329409|imex:IM-14275-1408 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011984.1|sgd:S000001158|dip:DIP-5306N|mint:P38824|ensemblfungi:YHR116W(gene)|ensemblfungi:YHR116W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|interpro:IPR009069(MTCP1)|interpro:IPR010625(CHCH) ensemblfungi:YLR182W(gene)|ensemblfungi:YLR182W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010845"(positive regulation of reciprocal meiotic recombination)|go:"GO:0030907"(MBF transcription complex)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR040822|rcsb pdb:1SW6|rcsb pdb:2XFV|rcsb pdb:5XW5|refseq:NP_013283.1|sgd:S000004172|dip:DIP-598N|mint:P09959 psi-mi:"MI:0469"(intact) - crc64:9B317FCACEEC493C figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:By2CGv6ozlq/BlxI8kLcFxT2FKo559292 rogid:rtovwtMGdOLKrOttgos4Ej9V160559292 intact-crc:EC8C732D623F02D4|rigid:cQv7BngYqVtQIV8gGoSS+1J4cCc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38828 uniprotkb:P39517 intact:EBI-24700|uniprotkb:D3DL71|ensemblfungi:YHR121W intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C psi-mi:lsm12_yeast(display_long)|uniprotkb:YHR121W(locus name)|uniprotkb:LSM12(gene name)|psi-mi:LSM12(display_short)|uniprotkb:Sm-like protein 12(gene name synonym) psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329420|imex:IM-14275-1409 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011989.1|sgd:S000001163|dip:DIP-5545N|mint:P38828|ensemblfungi:YHR121W(gene)|ensemblfungi:YHR121W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016070"(RNA metabolic process)|interpro:IPR016521(Uncharacterised conserved protein UCP007783, YHR121w)|interpro:IPR019181|interpro:IPR039683 sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) - crc64:062CFA56DF6F2CEE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6xw9WGjtFwkmKlO6QHoSSS2aMro559292 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 intact-crc:57B75A5CB6CB3EA5|rigid:TcasaKkqzgXvLCs5+noqBTabdx0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38828 uniprotkb:P53297 intact:EBI-24700|uniprotkb:D3DL71|ensemblfungi:YHR121W intact:EBI-12961|uniprotkb:D6VUW2|ensemblfungi:YGR178C psi-mi:lsm12_yeast(display_long)|uniprotkb:YHR121W(locus name)|uniprotkb:LSM12(gene name)|psi-mi:LSM12(display_short)|uniprotkb:Sm-like protein 12(gene name synonym) psi-mi:pbp1_yeast(display_long)|uniprotkb:PBP1(gene name)|psi-mi:PBP1(display_short)|uniprotkb:MRS16(gene name synonym)|uniprotkb:"Poly(A)-binding protein-binding protein"(gene name synonym)|uniprotkb:YGR178C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329431|imex:IM-14275-1410 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011989.1|sgd:S000001163|dip:DIP-5545N|mint:P38828|ensemblfungi:YHR121W(gene)|ensemblfungi:YHR121W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016070"(RNA metabolic process)|interpro:IPR016521(Uncharacterised conserved protein UCP007783, YHR121w)|interpro:IPR019181|interpro:IPR039683 sgd:S000003410|ensemblfungi:YGR178C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0043621"(protein self-association)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1901524"(regulation of mitophagy)|go:"GO:1904262"(negative regulation of TORC1 signaling)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR025852|ensemblfungi:YGR178C(gene)|refseq:NP_011694.3|mint:P53297|dip:DIP-2464N psi-mi:"MI:0469"(intact) - crc64:92005F3A2346193E figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6xw9WGjtFwkmKlO6QHoSSS2aMro559292 rogid:LtXvbFHbcIwi3NJgeab11QUU2nI559292 intact-crc:B719A78FCDCF222A|rigid:+6c7IP5s+H3lTiLv5rPonXhg8Es false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38829 uniprotkb:P40469 intact:EBI-24704|uniprotkb:D3DL72|ensemblfungi:YHR122W intact:EBI-11492|uniprotkb:P89106|uniprotkb:Q45U11|uniprotkb:D6VVF9|ensemblfungi:YIL128W psi-mi:yhs2_yeast(display_long)|uniprotkb:YHR122W(locus name) psi-mi:met18_yeast(display_long)|uniprotkb:MMS19(gene name synonym)|uniprotkb:MET18(gene name)|psi-mi:MET18(display_short)|uniprotkb:Methyl methanesulfonate-sensitivity protein 19(gene name synonym)|uniprotkb:YIL128W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329442|imex:IM-14275-1411 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011990.1|sgd:S000001164|dip:DIP-1837N|mint:P38829|ensemblfungi:YHR122W(gene)|ensemblfungi:YHR122W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0097361"(CIA complex)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR002744(Protein of unknown function DUF59)|interpro:IPR034904|interpro:IPR039796 ensemblfungi:YIL128W(gene)|ensemblfungi:YIL128W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0009411"(response to UV)|go:"GO:0010033"(response to organic substance)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024687|interpro:IPR029240|interpro:IPR039920|refseq:NP_012138.1|sgd:S000001390|mint:P40469|dip:DIP-1438N psi-mi:"MI:0469"(intact) crc64:0C5AF75D54C77BCA crc64:D05DCC488E098814 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wxEWSVEULCGKJmSvX3FzB9ejcaU559292 rogid:aGHI860LyIouqzxBbYcEPKipQWs559292 intact-crc:E4EDAE21EE8B5F2D|rigid:n1BEYwrrBje0Vs5f3NAHFtGN6Go false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38837 uniprotkb:P12684 intact:EBI-24733|uniprotkb:D3DL82|uniprotkb:Q6Q5G1|ensemblfungi:YHR133C intact:EBI-8384|uniprotkb:E9P8X3|uniprotkb:D6VZ84|ensemblfungi:YLR450W psi-mi:nsg1_yeast(display_long)|uniprotkb:INSIG homolog 1(gene name synonym)|uniprotkb:YHR133C(locus name)|uniprotkb:NSG1(gene name)|psi-mi:NSG1(display_short) psi-mi:hmdh2_yeast(display_long)|uniprotkb:L9324.2(orf name)|uniprotkb:YLR450W(locus name)|uniprotkb:HMG2(gene name)|psi-mi:HMG2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329453|imex:IM-14275-1412 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001175|refseq:NP_012001.1|dip:DIP-2775N|mint:P38837|ensemblfungi:YHR133C(gene)|ensemblfungi:YHR133C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR025929 refseq:NP_013555.1|sgd:S000004442|mint:P12684|dip:DIP-6277N|ensemblfungi:YLR450W(gene)|ensemblfungi:YLR450W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005635"(nuclear envelope)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0034399"(nuclear periphery)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|interpro:IPR025583 psi-mi:"MI:0469"(intact) - crc64:1FD9DCD3AC01B15E figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ALle5Ub0gjK3Uh+6sfIgbfa7BYw559292 rogid:6q1hM5csy4DSYUsSGyTr8M6b9r0559292 intact-crc:604B499BD3EC8D9E|rigid:GodNPZqxiM9FrcBpePDdlt2orgQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38839 uniprotkb:Q08281 intact:EBI-24742|uniprotkb:D3DL85|intact:EBI-36375|uniprotkb:P87290|ensemblfungi:YHR136C intact:EBI-2047093|uniprotkb:D6W1T1|uniprotkb:Q92271|ensemblfungi:YOL138C psi-mi:spl2_yeast(display_long)|uniprotkb:YHR136C(locus name)|uniprotkb:SPL2(gene name)|psi-mi:SPL2(display_short)|uniprotkb:Suppressor of PLC1 deletion protein 2(gene name synonym) psi-mi:rtc1_yeast(display_long)|uniprotkb:RTC1(gene name)|psi-mi:RTC1(display_short)|uniprotkb:SEA2(gene name synonym)|uniprotkb:SEH-associated protein 2(gene name synonym)|uniprotkb:YOL138C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329464|imex:IM-14275-1413 author score:99.32 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001178|refseq:NP_012004.1|dip:DIP-4089N|mint:P38839|ensemblfungi:YHR136C(gene)|ensemblfungi:YHR136C_mRNA(transcript)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006623"(protein targeting to vacuole) interpro:IPR037590|refseq:NP_014503.2|sgd:S000005498|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q08281|interpro:IPR036322|ensemblfungi:YOL138C(gene)|ensemblfungi:YOL138C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0035859"(Seh1-associated complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0097042"(extrinsic component of fungal-type vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.32|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I6KuR1VZPyKPbYSOGh5Mw95ZH40559292 rogid:3k6vZ9TxDj/BcLSmeJdAg45Ri14559292 intact-crc:B1499232FD5137A0|rigid:6tKLlimUNW15M8kq03OscOVV+Lg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:P38843 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-24756|uniprotkb:D3DL91|ensemblfungi:YHR142W psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:chs7_yeast(display_long)|uniprotkb:YHR142W(locus name)|uniprotkb:CHS7(gene name)|psi-mi:CHS7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329475|imex:IM-14275-1414 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 refseq:NP_012011.1|sgd:S000001184|mint:P38843|dip:DIP-5238N|ensemblfungi:YHR142W(gene)|ensemblfungi:YHR142W_mRNA(transcript)|go:"GO:0005628"(prospore membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071555"(cell wall organization)|interpro:IPR022057 psi-mi:"MI:0469"(intact) - crc64:9DA1EAFA181B2409 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:pyFq5p7Vk1l+5RhYA6CuqZeLl3c559292 intact-crc:7FB2FE640EB34F84|rigid:s+lD2mf3sVEUiZnbSL0IOXQUyks false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38843 uniprotkb:P29465 intact:EBI-24756|uniprotkb:D3DL91|ensemblfungi:YHR142W intact:EBI-4632|uniprotkb:D6VQ25|ensemblfungi:YBR023C psi-mi:chs7_yeast(display_long)|uniprotkb:YHR142W(locus name)|uniprotkb:CHS7(gene name)|psi-mi:CHS7(display_short) psi-mi:chs3_yeast(display_long)|uniprotkb:CHS3(gene name)|psi-mi:CHS3(display_short)|uniprotkb:CAL1(gene name synonym)|uniprotkb:DIT101(gene name synonym)|uniprotkb:KIT2(gene name synonym)|uniprotkb:YBR023C(locus name)|uniprotkb:CSD2(gene name synonym)|uniprotkb:YBR0305(orf name)|uniprotkb:Chitin-UDP acetyl-glucosaminyl transferase 3(gene name synonym)|uniprotkb:Class-IV chitin synthase 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329486|imex:IM-14275-1415 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012011.1|sgd:S000001184|mint:P38843|dip:DIP-5238N|ensemblfungi:YHR142W(gene)|ensemblfungi:YHR142W_mRNA(transcript)|go:"GO:0005628"(prospore membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071555"(cell wall organization)|interpro:IPR022057 refseq:NP_009579.1|sgd:S000000227|dip:DIP-2482N|mint:P29465|ensemblfungi:YBR023C(gene)|ensemblfungi:YBR023C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0004100"(chitin synthase activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030428"(cell septum)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0045009"(chitosome)|go:"GO:0071944"(cell periphery)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR004835(Fungal chitin synthase)|interpro:IPR029044|rcsb pdb:4WJW psi-mi:"MI:0469"(intact) crc64:9DA1EAFA181B2409 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pyFq5p7Vk1l+5RhYA6CuqZeLl3c559292 rogid:8Ik0u35UXSJVtqfgNdo49J+nzFk559292 intact-crc:1593C1AC96D02A55|rigid:EQfiEjBamP1yQGRhDmdSKgatwI8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38850 uniprotkb:Q8TGU5 intact:EBI-24788|uniprotkb:D3DLA3|ensemblfungi:YHR154W intact:EBI-2042814|uniprotkb:D6VQU1|ensemblfungi:YBR296C-A psi-mi:rt107_yeast(display_long)|uniprotkb:RTT107(gene name)|psi-mi:RTT107(display_short)|uniprotkb:ESC4(gene name synonym)|uniprotkb:Establishes silent chromatin protein 4(gene name synonym)|uniprotkb:YHR154W(locus name) psi-mi:yb296_yeast(display_long)|uniprotkb:YBR296C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329497|imex:IM-14275-1416 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012024.1|sgd:S000001197|mint:P38850|dip:DIP-6297N|ensemblfungi:YHR154W(gene)|ensemblfungi:YHR154W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0071944"(cell periphery)|go:"GO:1903775"(regulation of DNA double-strand break processing)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001357(BRCT)|interpro:IPR031906|interpro:IPR036420|rcsb pdb:3T7I|rcsb pdb:3T7J|rcsb pdb:3T7K|rcsb pdb:6J0V|rcsb pdb:6J0W|rcsb pdb:6J0X|rcsb pdb:6J0Y sgd:S000028605|refseq:NP_878055.3|mint:Q8TGU5|ensemblfungi:YBR296C-A(gene)|ensemblfungi:YBR296C-A_mRNA(transcript)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity) psi-mi:"MI:0469"(intact) crc64:767931285BB52580 - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nMtsA6HiKOfm0om1PzztCKNDfWU559292 rogid:DZubWD7lnwtea4Ne/bK1ITPFaJk559292 intact-crc:1C225F54EE7B7833|rigid:JbSIflTYdSWUx3AAii+J3cCLX20 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TGU5 uniprotkb:P38852 intact:EBI-2042814|uniprotkb:D6VQU1|ensemblfungi:YBR296C-A intact:EBI-570|uniprotkb:D3DLA5|ensemblfungi:YHR156C psi-mi:yb296_yeast(display_long)|uniprotkb:YBR296C-A(locus name) psi-mi:lin1_yeast(display_long)|uniprotkb:LIN1(gene name)|psi-mi:LIN1(display_short)|uniprotkb:YHR156C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329508|imex:IM-14275-1417 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000028605|refseq:NP_878055.3|mint:Q8TGU5|ensemblfungi:YBR296C-A(gene)|ensemblfungi:YBR296C-A_mRNA(transcript)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity) refseq:NP_012026.1|sgd:S000001199|dip:DIP-4407N|mint:P38852|ensemblfungi:YHR156C(gene)|ensemblfungi:YHR156C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|interpro:IPR003169(GYF)|interpro:IPR035445|interpro:IPR039905 psi-mi:"MI:0469"(intact) - crc64:59A10D63E0C8715C figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:DZubWD7lnwtea4Ne/bK1ITPFaJk559292 rogid:r28MUrEAITloyVxnvmCta0UyFL4559292 intact-crc:1E225F5D948848B7|rigid:bXTmJEgYpAVFxkFxUJ/4sGlCAno false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38853 uniprotkb:P38853 intact:EBI-9619|ensemblfungi:YHR158C|uniprotkb:D3DLA7|uniprotkb:E9P8X4 intact:EBI-9619|ensemblfungi:YHR158C|uniprotkb:D3DLA7|uniprotkb:E9P8X4 psi-mi:kel1_yeast(display_long)|uniprotkb:KEL1(gene name)|psi-mi:KEL1(display_short)|uniprotkb:YHR158C(locus name) psi-mi:kel1_yeast(display_long)|uniprotkb:KEL1(gene name)|psi-mi:KEL1(display_short)|uniprotkb:YHR158C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329519|imex:IM-14275-1418 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR158C(gene)|ensemblfungi:YHR158C_mRNA(transcript)|go:"GO:0000755"(cytogamy)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090337"(regulation of formin-nucleated actin cable assembly)|go:"GO:1990615"(Kelch-containing formin regulatory complex)|interpro:IPR015915(Kelch-type beta propeller)|refseq:NP_012028.1|sgd:S000001201|dip:DIP-1403N|mint:P38853 ensemblfungi:YHR158C(gene)|ensemblfungi:YHR158C_mRNA(transcript)|go:"GO:0000755"(cytogamy)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090337"(regulation of formin-nucleated actin cable assembly)|go:"GO:1990615"(Kelch-containing formin regulatory complex)|interpro:IPR015915(Kelch-type beta propeller)|refseq:NP_012028.1|sgd:S000001201|dip:DIP-1403N|mint:P38853 psi-mi:"MI:0469"(intact) crc64:43D0FC570F1D5E4D crc64:43D0FC570F1D5E4D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pdHtsxpdf1r7G2K9e9EPHajJS3w559292 rogid:pdHtsxpdf1r7G2K9e9EPHajJS3w559292 intact-crc:0C2B1F0A4D7D2B32|rigid:cno0WsQ+5PExykGofARd8EfHanw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38853 uniprotkb:P50090 intact:EBI-9619|ensemblfungi:YHR158C|uniprotkb:D3DLA7|uniprotkb:E9P8X4 intact:EBI-9630|ensemblfungi:YGR238C|uniprotkb:D6VV18 psi-mi:kel1_yeast(display_long)|uniprotkb:KEL1(gene name)|psi-mi:KEL1(display_short)|uniprotkb:YHR158C(locus name) psi-mi:kel2_yeast(display_long)|uniprotkb:KEL2(gene name)|psi-mi:KEL2(display_short)|uniprotkb:G8585(orf name)|uniprotkb:YGR238C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329530|imex:IM-14275-1419 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR158C(gene)|ensemblfungi:YHR158C_mRNA(transcript)|go:"GO:0000755"(cytogamy)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090337"(regulation of formin-nucleated actin cable assembly)|go:"GO:1990615"(Kelch-containing formin regulatory complex)|interpro:IPR015915(Kelch-type beta propeller)|refseq:NP_012028.1|sgd:S000001201|dip:DIP-1403N|mint:P38853 go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090337"(regulation of formin-nucleated actin cable assembly)|go:"GO:1990615"(Kelch-containing formin regulatory complex)|interpro:IPR015915(Kelch-type beta propeller)|ensemblfungi:YGR238C(gene)|ensemblfungi:YGR238C_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0008360"(regulation of cell shape)|refseq:NP_011754.3|sgd:S000003470|dip:DIP-4229N|mint:P50090 psi-mi:"MI:0469"(intact) crc64:43D0FC570F1D5E4D crc64:63B9772FF017E6D9 figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pdHtsxpdf1r7G2K9e9EPHajJS3w559292 rogid:lSnioafH7gyCBHbl539AXlWBAxE559292 intact-crc:5076C9A7DA279E1D|rigid:j3fxfssltKjMoDuiB8X1j+KatoQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38865 uniprotkb:P38310 intact:EBI-5268|uniprotkb:D3DLC3|ensemblfungi:YHR175W intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:ctr2_yeast(display_long)|uniprotkb:CTR2(gene name)|psi-mi:CTR2(display_short)|uniprotkb:YHR175W(locus name) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329541|imex:IM-14275-1420 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001218|refseq:NP_012045.3|dip:DIP-4763N|mint:P38865|ensemblfungi:YHR175W(gene)|ensemblfungi:YHR175W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005375"(copper ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0015677"(copper ion import)|go:"GO:0015680"(protein maturation by copper ion transfer)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007274(Ctr copper transporter)|reactome:R-SCE-425410 refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) - crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+wZ6yXvQ4IcQ2hLZAPvxn3qeg6w559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:6552BFF63010A445|rigid:+X8w19fN/I16Qrmego69xv7W4qE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38865 uniprotkb:P38865 intact:EBI-5268|uniprotkb:D3DLC3|ensemblfungi:YHR175W intact:EBI-5268|uniprotkb:D3DLC3|ensemblfungi:YHR175W psi-mi:ctr2_yeast(display_long)|uniprotkb:CTR2(gene name)|psi-mi:CTR2(display_short)|uniprotkb:YHR175W(locus name) psi-mi:ctr2_yeast(display_long)|uniprotkb:CTR2(gene name)|psi-mi:CTR2(display_short)|uniprotkb:YHR175W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329552|imex:IM-14275-1421 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001218|refseq:NP_012045.3|dip:DIP-4763N|mint:P38865|ensemblfungi:YHR175W(gene)|ensemblfungi:YHR175W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005375"(copper ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0015677"(copper ion import)|go:"GO:0015680"(protein maturation by copper ion transfer)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007274(Ctr copper transporter)|reactome:R-SCE-425410 sgd:S000001218|refseq:NP_012045.3|dip:DIP-4763N|mint:P38865|ensemblfungi:YHR175W(gene)|ensemblfungi:YHR175W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005375"(copper ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0015677"(copper ion import)|go:"GO:0015680"(protein maturation by copper ion transfer)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007274(Ctr copper transporter)|reactome:R-SCE-425410 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+wZ6yXvQ4IcQ2hLZAPvxn3qeg6w559292 rogid:+wZ6yXvQ4IcQ2hLZAPvxn3qeg6w559292 intact-crc:09FEEED879F8290E|rigid:A9dH3FgqtuzG8hog+Ry4gdLDjA0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38865 uniprotkb:P38929 intact:EBI-5268|uniprotkb:D3DLC3|ensemblfungi:YHR175W intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W psi-mi:ctr2_yeast(display_long)|uniprotkb:CTR2(gene name)|psi-mi:CTR2(display_short)|uniprotkb:YHR175W(locus name) psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329563|imex:IM-14275-1422 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001218|refseq:NP_012045.3|dip:DIP-4763N|mint:P38865|ensemblfungi:YHR175W(gene)|ensemblfungi:YHR175W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005375"(copper ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0015677"(copper ion import)|go:"GO:0015680"(protein maturation by copper ion transfer)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007274(Ctr copper transporter)|reactome:R-SCE-425410 refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 psi-mi:"MI:0469"(intact) - crc64:5BD9ECFF8508F396 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+wZ6yXvQ4IcQ2hLZAPvxn3qeg6w559292 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 intact-crc:40FD20E4523A5677|rigid:PuBsFT/C1TsiW5LkfyQj5hdI4jQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39010 uniprotkb:P38865 intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C intact:EBI-5268|uniprotkb:D3DLC3|ensemblfungi:YHR175W psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:ctr2_yeast(display_long)|uniprotkb:CTR2(gene name)|psi-mi:CTR2(display_short)|uniprotkb:YHR175W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329574|imex:IM-14275-1423 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 sgd:S000001218|refseq:NP_012045.3|dip:DIP-4763N|mint:P38865|ensemblfungi:YHR175W(gene)|ensemblfungi:YHR175W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005375"(copper ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0015677"(copper ion import)|go:"GO:0015680"(protein maturation by copper ion transfer)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007274(Ctr copper transporter)|reactome:R-SCE-425410 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 rogid:+wZ6yXvQ4IcQ2hLZAPvxn3qeg6w559292 intact-crc:DB084AC0D91ECA15|rigid:A1ko5/tLLzO9cIUkXW4TfMzz9+g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46989 uniprotkb:P38865 intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C intact:EBI-5268|uniprotkb:D3DLC3|ensemblfungi:YHR175W psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:ctr2_yeast(display_long)|uniprotkb:CTR2(gene name)|psi-mi:CTR2(display_short)|uniprotkb:YHR175W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329585|imex:IM-14275-1424 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 sgd:S000001218|refseq:NP_012045.3|dip:DIP-4763N|mint:P38865|ensemblfungi:YHR175W(gene)|ensemblfungi:YHR175W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005375"(copper ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0015677"(copper ion import)|go:"GO:0015680"(protein maturation by copper ion transfer)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007274(Ctr copper transporter)|reactome:R-SCE-425410 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 rogid:+wZ6yXvQ4IcQ2hLZAPvxn3qeg6w559292 intact-crc:1148CB21EF12C838|rigid:byK5ZlyIG9lFCaWYe+iE2d79reI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:P38865 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-5268|uniprotkb:D3DLC3|ensemblfungi:YHR175W psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:ctr2_yeast(display_long)|uniprotkb:CTR2(gene name)|psi-mi:CTR2(display_short)|uniprotkb:YHR175W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329596|imex:IM-14275-1425 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 sgd:S000001218|refseq:NP_012045.3|dip:DIP-4763N|mint:P38865|ensemblfungi:YHR175W(gene)|ensemblfungi:YHR175W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005375"(copper ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0015677"(copper ion import)|go:"GO:0015680"(protein maturation by copper ion transfer)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007274(Ctr copper transporter)|reactome:R-SCE-425410 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:+wZ6yXvQ4IcQ2hLZAPvxn3qeg6w559292 intact-crc:1F1E8B88F6E74C3E|rigid:QKrT4pyRMnh5GdK4AUW+jKLIcoY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38874 uniprotkb:P38874 intact:EBI-9061|ensemblfungi:YHR187W|uniprotkb:D3DLD5 intact:EBI-9061|ensemblfungi:YHR187W|uniprotkb:D3DLD5 psi-mi:elp5_yeast(display_long)|uniprotkb:YHR187W(locus name)|uniprotkb:IKI1(gene name)|psi-mi:IKI1(display_short)|uniprotkb:ELP5(gene name synonym)|uniprotkb:HAP2(gene name synonym)|uniprotkb:TOT5(gene name synonym)|uniprotkb:Gamma-toxin target 5(gene name synonym)|uniprotkb:Protein IKI1(gene name synonym)|uniprotkb:HAT-associated protein 2(gene name synonym) psi-mi:elp5_yeast(display_long)|uniprotkb:YHR187W(locus name)|uniprotkb:IKI1(gene name)|psi-mi:IKI1(display_short)|uniprotkb:ELP5(gene name synonym)|uniprotkb:HAP2(gene name synonym)|uniprotkb:TOT5(gene name synonym)|uniprotkb:Gamma-toxin target 5(gene name synonym)|uniprotkb:Protein IKI1(gene name synonym)|uniprotkb:HAT-associated protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329607|imex:IM-14275-1426 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001230|ensemblfungi:YHR187W(gene)|ensemblfungi:YHR187W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR019519|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS|refseq:NP_012057.3|dip:DIP-1967N|mint:P38874 sgd:S000001230|ensemblfungi:YHR187W(gene)|ensemblfungi:YHR187W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR019519|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS|refseq:NP_012057.3|dip:DIP-1967N|mint:P38874 psi-mi:"MI:0469"(intact) crc64:DFD93D7BA583E2F5 crc64:DFD93D7BA583E2F5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Xl/ausdL/d79OM78at6ZZldvBMg559292 rogid:Xl/ausdL/d79OM78at6ZZldvBMg559292 intact-crc:89795CF1C3ED62DE|rigid:n/85op2sat0oQnmRvkrqXH74Rjc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42935 uniprotkb:P38874 intact:EBI-23459|uniprotkb:D6VUY2|uniprotkb:E9P8V1|ensemblfungi:YGR200C intact:EBI-9061|ensemblfungi:YHR187W|uniprotkb:D3DLD5 psi-mi:elp2_yeast(display_long)|uniprotkb:YGR200C(locus name)|uniprotkb:G7725(orf name)|uniprotkb:ELP2(gene name)|psi-mi:ELP2(display_short)|uniprotkb:TOT2(gene name synonym)|uniprotkb:Gamma-toxin target 2(gene name synonym) psi-mi:elp5_yeast(display_long)|uniprotkb:YHR187W(locus name)|uniprotkb:IKI1(gene name)|psi-mi:IKI1(display_short)|uniprotkb:ELP5(gene name synonym)|uniprotkb:HAP2(gene name synonym)|uniprotkb:TOT5(gene name synonym)|uniprotkb:Gamma-toxin target 5(gene name synonym)|uniprotkb:Protein IKI1(gene name synonym)|uniprotkb:HAT-associated protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329618|imex:IM-14275-1427 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003432|refseq:NP_011716.3|dip:DIP-2386N|mint:P42935|ensemblfungi:YGR200C(gene)|ensemblfungi:YGR200C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008017"(microtubule binding)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0015031"(protein transport)|go:"GO:0032447"(protein urmylation)|go:"GO:0033588"(elongator holoenzyme complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037289|rcsb pdb:4XFV|rcsb pdb:5M2N|rcsb pdb:6QK7 sgd:S000001230|ensemblfungi:YHR187W(gene)|ensemblfungi:YHR187W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR019519|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS|refseq:NP_012057.3|dip:DIP-1967N|mint:P38874 psi-mi:"MI:0469"(intact) crc64:5371908FE2E6EC0D crc64:DFD93D7BA583E2F5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:uBbnUH2xCo3Fu5LlxbrLxO43irk559292 rogid:Xl/ausdL/d79OM78at6ZZldvBMg559292 intact-crc:EBE5F8B651C88491|rigid:njqhR2plDOCiSwwei8fJXIihc9E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38880 uniprotkb:P15496 intact:EBI-24880|uniprotkb:D3DLE2|ensemblfungi:YHR194W intact:EBI-8902|ensemblfungi:YPL117C|uniprotkb:D6W3Q1 psi-mi:mdm31_yeast(display_long)|uniprotkb:MDM31(gene name)|psi-mi:MDM31(display_short)|uniprotkb:YHR194W(locus name) psi-mi:idi1_yeast(display_long)|uniprotkb:Isopentenyl pyrophosphate isomerase(gene name synonym)|uniprotkb:IDI1(gene name)|psi-mi:IDI1(display_short)|uniprotkb:BOT2(gene name synonym)|uniprotkb:YPL117C(locus name)|uniprotkb:LPH10C(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329629|imex:IM-14275-1428 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012064.1|sgd:S000001237|mint:P38880|dip:DIP-2828N|ensemblfungi:YHR194W(gene)|ensemblfungi:YHR194W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006873"(cellular ion homeostasis)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:1900208"(regulation of cardiolipin metabolic process)|interpro:IPR012571(Mitochondrial distribution and morphology protein family 31/32, fungi) ensemblfungi:YPL117C(gene)|ensemblfungi:YPL117C_mRNA(transcript)|go:"GO:0004452"(isopentenyl-diphosphate delta-isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009240"(isopentenyl diphosphate biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0045337"(farnesyl diphosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050992"(dimethylallyl diphosphate biosynthetic process)|reactome:R-SCE-191273|refseq:NP_015208.1|sgd:S000006038|interpro:IPR011876(Isopentenyl-diphosphate delta-isomerase, type 1)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|mint:P15496 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:f1PO3YNFunXXfkaeUqI1NPSpblE559292 rogid:KQ9qSb2grQ4DQip7atYPeCwp5QM559292 intact-crc:B63E35030E9784FD|rigid:u4xC+fhyk7U9soxEEVhceVaCcsQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38903 uniprotkb:P36027 intact:EBI-1931|uniprotkb:D6W281|ensemblfungi:YOR014W intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:2a5d_yeast(display_long)|uniprotkb:RTS1(gene name)|psi-mi:RTS1(display_short)|uniprotkb:SCS1(gene name synonym)|uniprotkb:YOR014W(locus name)|uniprotkb:OR26.04(orf name)|uniprotkb:PP2A, B subunit, B' delta isoform(gene name synonym)|uniprotkb:Protein RTS1(gene name synonym)|uniprotkb:Protein SCS1(gene name synonym) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329640|imex:IM-14275-1429 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014657.1|sgd:S000005540|dip:DIP-4191N|mint:P38903|ensemblfungi:YOR014W(gene)|ensemblfungi:YOR014W_mRNA(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006281"(DNA repair)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031107"(septin ring disassembly)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0070199"(establishment of protein localization to chromosome)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-389513|reactome:R-SCE-6811558 ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) crc64:5A7476C30140331C - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rTkFihe+ijbI4Re8aagUl4clGtE559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:5A37F7F00C75C706|rigid:2a9/En1c+ldHY0rnz86bjYDofzY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02486 uniprotkb:P38920 intact:EBI-2028|uniprotkb:Q712M5|uniprotkb:D6VZP6|ensemblfungi:YMR072W intact:EBI-11003|uniprotkb:Q2I028|uniprotkb:Q2I029|uniprotkb:Q2I031|uniprotkb:Q2I032|uniprotkb:Q2I033|uniprotkb:Q2I034|uniprotkb:Q2I035|uniprotkb:Q2I036|uniprotkb:Q2I038|uniprotkb:Q2I039|uniprotkb:Q2I041|ensemblfungi:YMR167W|uniprotkb:D6VZY9 psi-mi:abf2_yeast(display_long)|uniprotkb:ABF2(gene name)|psi-mi:ABF2(display_short)|uniprotkb:HIM1(gene name synonym)|uniprotkb:YMR072W(locus name)|uniprotkb:YM9916.11(orf name) psi-mi:mlh1_yeast(display_long)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:YMR167W(locus name)|uniprotkb:YM8520.16(orf name)|uniprotkb:PMS2(gene name synonym)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:Post meiotic segregation protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329651|imex:IM-14275-1430 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013788.1|sgd:S000004676|dip:DIP-5492N|mint:Q02486|ensemblfungi:YMR072W(gene)|ensemblfungi:YMR072W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000262"(mitochondrial chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0090139"(mitochondrial DNA packaging)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR033311|interpro:IPR036910|rcsb pdb:5JGH|rcsb pdb:5JH0|reactome:R-SCE-140342|reactome:R-SCE-5620971|reactome:R-SCE-5686938|reactome:R-SCE-6798695 rcsb pdb:6SNS|rcsb pdb:6SNV|reactome:R-SCE-5358565|ensemblfungi:YMR167W(gene)|ensemblfungi:YMR167W_mRNA(transcript)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000713"(meiotic heteroduplex formation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006298"(mismatch repair)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0032390"(MutLbeta complex)|go:"GO:0097587"(MutLgamma complex)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|rcsb pdb:4E4W|rcsb pdb:4FMN|rcsb pdb:4FMO|rcsb pdb:6RMN|rcsb pdb:6SHX|refseq:NP_013890.1|sgd:S000004777|mint:P38920|dip:DIP-2412N psi-mi:"MI:0469"(intact) - crc64:B2DBB31DE3943171 figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:/CTWlLyBSqcUfnauZoEdbNH/tnE559292 rogid:rZq8/zWV2xAiYIDDuGGsp+YjSnY559292 intact-crc:76847A85D60B93E0|rigid:s6A86M3zVeIKLydBoGW0/iH2MzQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32386 uniprotkb:P38929 intact:EBI-21511|uniprotkb:Q07882|uniprotkb:D6VXW0|ensemblfungi:YLL048C intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W psi-mi:ybt1_yeast(display_long)|uniprotkb:YBT1(gene name)|psi-mi:YBT1(display_short)|uniprotkb:BAT1(gene name synonym)|uniprotkb:YLL048C(locus name) psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329662|imex:IM-14275-1431 author score:99.34 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013052.1|sgd:S000003971|mint:P32386|dip:DIP-6474N|ensemblfungi:YLL048C(gene)|ensemblfungi:YLL048C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006816"(calcium ion transport)|go:"GO:0015718"(monocarboxylic acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033285"(ATPase-coupled monocarboxylic acid transmembrane transporter activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 psi-mi:"MI:0469"(intact) crc64:E71D3D57A3013C38 crc64:5BD9ECFF8508F396 figure legend:tables S3 and S4|author-confidence:99.34|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:b0Cz526nha/7DJPmG1uADmBnNPA559292 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 intact-crc:7A3416CBB591137B|rigid:Kr9MZ11FeLg2XwRWevUdTBARBaY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38929 uniprotkb:P32465 intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329673|imex:IM-14275-1432 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N psi-mi:"MI:0469"(intact) crc64:5BD9ECFF8508F396 - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 intact-crc:09FD70764C605042|rigid:A6VwZuikvI+sD30atR3CpNFcnS0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32563 uniprotkb:P38929 intact:EBI-20455|uniprotkb:D6W2X0|ensemblfungi:YOR270C intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W psi-mi:vph1_yeast(display_long)|uniprotkb:VPH1(gene name)|psi-mi:VPH1(display_short)|uniprotkb:Vacuolar proton pump a subunit(gene name synonym)|uniprotkb:V-ATPase 95 kDa subunit(gene name synonym)|uniprotkb:Vacuolar pH protein 1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase subunit a 1(gene name synonym)|uniprotkb:YOR270C(locus name) psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329684|imex:IM-14275-1433 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005796|refseq:NP_014913.3|ensemblfungi:YOR270C(gene)|ensemblfungi:YOR270C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0034622"|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:0071469"(cellular response to alkaline pH)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|rcsb pdb:2JTW|rcsb pdb:2NVJ|rcsb pdb:2RPW|rcsb pdb:3J9T|go:"GO:0007035"(vacuolar acidification)|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5I1M|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6HH0|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2960N|mint:P32563 refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 psi-mi:"MI:0469"(intact) crc64:77709A914410CD4D crc64:5BD9ECFF8508F396 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:c+aKW/ZUnBlGW7ZqOLD/0mpICdQ559292 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 intact-crc:C11E20DDC371BCB7|rigid:TZ00WRgYIvXYGV/whhKjtTPD5R4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38929 uniprotkb:P32610 intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329695|imex:IM-14275-1434 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610 psi-mi:"MI:0469"(intact) crc64:5BD9ECFF8508F396 crc64:FDE93E1FAF0AEC5B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292 intact-crc:9D0931001BC4BF32|rigid:es2wnVOfMwAjunosAyK4SqF5FUI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38929 uniprotkb:P32798 intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W intact:EBI-5006|uniprotkb:D6W314|ensemblfungi:YOR316C psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:cot1_yeast(display_long)|uniprotkb:COT1(gene name)|psi-mi:COT1(display_short)|uniprotkb:O6131(orf name)|uniprotkb:YOR316C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329706|imex:IM-14275-1435 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 sgd:S000005843|refseq:NP_014961.3|dip:DIP-7554N|mint:P32798|ensemblfungi:YOR316C(gene)|ensemblfungi:YOR316C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006824"(cobalt ion transport)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0015087"(cobalt ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410 psi-mi:"MI:0469"(intact) crc64:5BD9ECFF8508F396 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 rogid:HEIg6lhS698E9H3BJeESYAipNwA559292 intact-crc:40EE5025D5E70C99|rigid:jpFqFKo7hoTLIUzWrqj1UCAsCbc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38929 uniprotkb:P34110 intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W intact:EBI-20415|uniprotkb:D6VW33|ensemblfungi:YJL154C psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:vps35_yeast(display_long)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:Vacuolar protein-targeting protein 7(gene name synonym)|uniprotkb:VPT7(gene name synonym)|uniprotkb:J0580(orf name)|uniprotkb:YJL154C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329717|imex:IM-14275-1436 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 refseq:NP_012381.1|sgd:S000003690|ensemblfungi:YJL154C(gene)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1904377"(positive regulation of protein localization to cell periphery)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR042491|reactome:R-SCE-3238698|ensemblfungi:YJL154C_mRNA(transcript)|dip:DIP-1743N|mint:P34110 psi-mi:"MI:0469"(intact) crc64:5BD9ECFF8508F396 crc64:DE1BC57B9DFB606E figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 rogid:5KBi/lSF+BsMyg9ulP9eLCp2xCc559292 intact-crc:398375461BDB96D1|rigid:QjeTkAy1nzpdePVB37H91kV461k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38929 uniprotkb:P38310 intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329728|imex:IM-14275-1437 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) crc64:5BD9ECFF8508F396 crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:2C5171CA1BD2DB3C|rigid:Xv02bus7//Y0+bfDswvdZMDkf0o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38929 uniprotkb:P38929 intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329739|imex:IM-14275-1438 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 psi-mi:"MI:0469"(intact) crc64:5BD9ECFF8508F396 crc64:5BD9ECFF8508F396 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 intact-crc:8F9641D35EE1AE77|rigid:Ffzs19kp2f7PQi5RJ7WWUv4XGTA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39111 uniprotkb:P38929 intact:EBI-20272|uniprotkb:D6VUF5|ensemblfungi:YGR020C intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W psi-mi:vatf_yeast(display_long)|uniprotkb:VMA7(gene name)|psi-mi:VMA7(display_short)|uniprotkb:YGR020C(locus name)|uniprotkb:Vacuolar proton pump subunit F(gene name synonym)|uniprotkb:V-ATPase 14 kDa subunit(gene name synonym) psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329750|imex:IM-14275-1439 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011534.1|sgd:S000003252|ensemblfungi:YGR020C(gene)|ensemblfungi:YGR020C_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016020"(membrane)|go:"GO:0042625"(ATPase-coupled ion transmembrane transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005772(ATPase, V1 complex, subunit F, eukaryotic)|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|interpro:IPR036906|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4IX9|rcsb pdb:4RND|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2077N|mint:P39111 refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 psi-mi:"MI:0469"(intact) crc64:D21EC0980EB99DFF crc64:5BD9ECFF8508F396 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VtthQl2jj9fpjv3psX0YUNbIAKU559292 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 intact-crc:F48B7F68FB1749B5|rigid:WrauXB++y2m/hleNi0LVt6SuqP4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39968 uniprotkb:P38929 intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name) psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329761|imex:IM-14275-1440 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 psi-mi:"MI:0469"(intact) crc64:B2E75774B47E5933 crc64:5BD9ECFF8508F396 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 intact-crc:FAEEFF865A89077F|rigid:zKJDuZkQs8oK/5DbbLcUNkYxJeg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38929 uniprotkb:P41807 intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W intact:EBI-20281|uniprotkb:D6W446|ensemblfungi:YPR036W psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:vath_yeast(display_long)|uniprotkb:YP3085.02(orf name)|uniprotkb:VMA13(gene name)|psi-mi:VMA13(display_short)|uniprotkb:CLS11(gene name synonym)|uniprotkb:YPR036W(locus name)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 54 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329772|imex:IM-14275-1441 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 refseq:NP_015361.1|sgd:S000006240|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|rcsb pdb:1HO8|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YPR036W(gene)|ensemblfungi:YPR036W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|dip:DIP-6640N|mint:P41807 psi-mi:"MI:0469"(intact) crc64:5BD9ECFF8508F396 crc64:54131FF9C2C87594 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 rogid:kEXWvOsnTk0WdgGOny+mufz4lTo559292 intact-crc:39EDE88D056A729A|rigid:p2UAxGjvX0yNKb70/0qLTSwxa9Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38929 uniprotkb:P46989 intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329783|imex:IM-14275-1442 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:5BD9ECFF8508F396 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 intact-crc:DE23AA16E3C93038|rigid:0GX3aYsV7CDWyb3U6tioHZiiyjw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53290 uniprotkb:P38929 intact:EBI-7962|uniprotkb:D6VUU7|ensemblfungi:YGR163W intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W psi-mi:gtr2_yeast(display_long)|uniprotkb:YGR163W(locus name)|uniprotkb:GTR2(gene name)|psi-mi:GTR2(display_short) psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329794|imex:IM-14275-1443 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003395|refseq:NP_011679.3|mint:P53290|dip:DIP-4521N|ensemblfungi:YGR163W(gene)|ensemblfungi:YGR163W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000785"(chromatin)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039400|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 psi-mi:"MI:0469"(intact) crc64:0A0D16C81F73184D crc64:5BD9ECFF8508F396 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+b9bPvzin/YUc5fOZZVCcFu/GEM559292 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 intact-crc:C6D9F779897F9CBF|rigid:rdI8Q5dQJpMcRu+OJtI9kRaoFtQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02205 uniprotkb:P38929 intact:EBI-27062|uniprotkb:D6VX73|ensemblfungi:YKR007W intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W psi-mi:meh1_yeast(display_long)|uniprotkb:GSE complex subunit 2(gene name synonym)|uniprotkb:EGO complex subunit 1(gene name synonym)|uniprotkb:YKR007W(locus name)|uniprotkb:YK106(orf name)|uniprotkb:MEH1(gene name)|psi-mi:MEH1(display_short)|uniprotkb:EGO1(gene name synonym)|uniprotkb:GSE2(gene name synonym) psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329805|imex:IM-14275-1444 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001715|refseq:NP_012932.1|mint:Q02205|dip:DIP-1922N|ensemblfungi:YKR007W(gene)|ensemblfungi:YKR007W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0005829"(cytosol)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007040"(lysosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR028209|rcsb pdb:4XPM|rcsb pdb:6JWP refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 psi-mi:"MI:0469"(intact) crc64:995DD1E68331D050 crc64:5BD9ECFF8508F396 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:73a6e5W5wQixGg2aGXDo4A6NR2s559292 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 intact-crc:36595D61E5595584|rigid:Auu661pfWJ9l0zejHZC5loZh5ts false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03730 uniprotkb:P38929 intact:EBI-27739|uniprotkb:Q6B2K7|uniprotkb:D6VZF6|ensemblfungi:YML018C intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W psi-mi:ymb8_yeast(display_long)|uniprotkb:YML018C(locus name) psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329816|imex:IM-14275-1445 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004480|refseq:NP_013694.1|dip:DIP-4953N|mint:Q03730|ensemblfungi:YML018C(gene)|ensemblfungi:YML018C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane) refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 psi-mi:"MI:0469"(intact) crc64:DEC5C3EEF293F5ED crc64:5BD9ECFF8508F396 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4WxEFdhqbP7pcRcTLeFHljCVQ34559292 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 intact-crc:394FC1C0A3A7FA61|rigid:S+9NW36BW3KFSxvCAQetE/WkTaE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06328 uniprotkb:P38929 intact:EBI-37173|uniprotkb:D6VSY2|ensemblfungi:YDR352W intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W psi-mi:ypq2_yeast(display_long)|uniprotkb:YPQ2(gene name)|psi-mi:YPQ2(display_short)|uniprotkb:PQ-loop repeat-containing protein 2(gene name synonym)|uniprotkb:YDR352W(locus name) psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329827|imex:IM-14275-1446 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010639.1|sgd:S000002760|interpro:IPR006603(Cystinosin/ERS1p repeat)|mint:Q06328|ensemblfungi:YDR352W(gene)|ensemblfungi:YDR352W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0015174"(basic amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034488"(basic amino acid transmembrane export from vacuole)|go:"GO:0071627"(integral component of fungal-type vacuolar membrane)|reactome:R-SCE-5223345 refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 psi-mi:"MI:0469"(intact) - crc64:5BD9ECFF8508F396 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tLoew2CtLfiBlJVBfq1TPSEozJk559292 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 intact-crc:D9DF4B3FDB9FD5FB|rigid:dKVViAHSxnZwsyl6WySF9RcVETQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06815 uniprotkb:P38929 intact:EBI-33784|uniprotkb:D6W481|ensemblfungi:YPR079W intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W psi-mi:mrl1_yeast(display_long)|uniprotkb:YPR079W(locus name)|uniprotkb:MRL1(gene name)|psi-mi:MRL1(display_short) psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329838|imex:IM-14275-1447 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015404.1|sgd:S000006283|mint:Q06815|dip:DIP-2873N|ensemblfungi:YPR079W(gene)|ensemblfungi:YPR079W_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007034"(vacuolar transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR036607|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 psi-mi:"MI:0469"(intact) - crc64:5BD9ECFF8508F396 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:PFMxRfVBupoO0p3pb+BB5H2fidg559292 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 intact-crc:8DD3E3AE682D5D07|rigid:e24F8qLig1F0lV64PMHR8GoK+tM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38929 uniprotkb:Q12016 intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W intact:EBI-29309|uniprotkb:D6W1T9|ensemblfungi:YOL129W psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:vps68_yeast(display_long)|uniprotkb:YOL129W(locus name)|uniprotkb:VPS68(gene name)|psi-mi:VPS68(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329849|imex:IM-14275-1448 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 refseq:NP_014512.1|sgd:S000005489|dip:DIP-1732N|mint:Q12016|ensemblfungi:YOL129W(gene)|ensemblfungi:YOL129W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0034424"(Vps55/Vps68 complex)|interpro:IPR007919(Protein of unknown function UPF0220) psi-mi:"MI:0469"(intact) crc64:5BD9ECFF8508F396 crc64:4B21C846AB3BA2A7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 rogid:I6sUyfNcLBsFG3OtDUfEqohxLB4559292 intact-crc:9880F923E49503E9|rigid:OtHyDJcPIhbvleLdOJ5+rMIUb6I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38929 uniprotkb:Q12116 intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W intact:EBI-19306|uniprotkb:D6VS91|ensemblfungi:YDR105C psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:tms1_yeast(display_long)|uniprotkb:YDR105C(locus name)|uniprotkb:TMS1(gene name)|psi-mi:TMS1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329860|imex:IM-14275-1449 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 sgd:S000002512|ensemblfungi:YDR105C(gene)|ensemblfungi:YDR105C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR005016(TMS membrane protein/tumour differentially expressed protein)|interpro:IPR029559|reactome:R-SCE-977347|refseq:NP_010390.3|dip:DIP-5198N|mint:Q12116 psi-mi:"MI:0469"(intact) crc64:5BD9ECFF8508F396 crc64:DFA9011F9D56EEDE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 rogid:2r+KaCny/GXJUQ87u+f97/LLn+k559292 intact-crc:E7D1A69AEFB3261D|rigid:v12dr1gUPlzOP2ioS0T6iHd8RcQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q2V2P9 uniprotkb:P38929 intact:EBI-6329877|ensemblfungi:YDR119W-A|uniprotkb:D6VSA5 intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W psi-mi:cox26_yeast(display_long)|uniprotkb:COX26(gene name)|psi-mi:COX26(display_short)|uniprotkb:YDR119W-A(locus name) psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329872|imex:IM-14275-1450 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR119W-A(gene)|ensemblfungi:YDR119W-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:6HU9|rcsb pdb:6T0B|rcsb pdb:6T15|rcsb pdb:6YMX|rcsb pdb:6YMY|mint:Q2V2P9|refseq:NP_001032575.1|sgd:S000113555 refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 psi-mi:"MI:0469"(intact) - crc64:5BD9ECFF8508F396 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:y+ngl2QASMkgvhfqYQcKuy/Cd9A559292 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 intact-crc:806D0633CDC0CE43|rigid:I4lVYyhg4zOheYotDp5FDVEnlIs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15790 uniprotkb:P38930 intact:EBI-9533|ensemblfungi:YIL035C|uniprotkb:D6VVP7 intact:EBI-9578|ensemblfungi:YOR039W|uniprotkb:D6W2A6 psi-mi:csk21_yeast(display_long)|uniprotkb:YIL035C(locus name)|uniprotkb:CKA1(gene name)|psi-mi:CKA1(display_short) psi-mi:csk2c_yeast(display_long)|uniprotkb:CKB2(gene name)|psi-mi:CKB2(display_short)|uniprotkb:OR26.32(orf name)|uniprotkb:YOR039W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329885|imex:IM-14275-1451 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012229.1|sgd:S000001297|ensemblfungi:YIL035C(gene)|ensemblfungi:YIL035C_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007535"(donor selection)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0034456"(UTP-C complex)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:4FI1|rcsb pdb:4JQE|rcsb pdb:4JR7|rcsb pdb:4LFI|rcsb pdb:4MWH|reactome:R-SCE-2514853|reactome:R-SCE-6804756|reactome:R-SCE-8934903|reactome:R-SCE-8948751|mint:P15790|dip:DIP-48N ensemblfungi:YOR039W(gene)|ensemblfungi:YOR039W_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0032545"(CURI complex)|go:"GO:0034456"(UTP-C complex)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|reactome:R-SCE-2514853|reactome:R-SCE-6798695|reactome:R-SCE-6804756|reactome:R-SCE-8934903|reactome:R-SCE-8948751|refseq:NP_014682.1|sgd:S000005565|mint:P38930|dip:DIP-262N psi-mi:"MI:0469"(intact) crc64:6A1A7F1BF47250C9 crc64:D6060CB3D70B19A4 figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SNrrYvyWdzd6bAyvluPlZqs5WJw559292 rogid:X+0JSYVQigL0wSbWYCkorc8jqpw559292 intact-crc:55411835D058891F|rigid:uFP6J1uSEj1gtEoxmZknduNPh8Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19454 uniprotkb:P38930 intact:EBI-9548|ensemblfungi:YOR061W|uniprotkb:D6W2C4 intact:EBI-9578|ensemblfungi:YOR039W|uniprotkb:D6W2A6 psi-mi:csk22_yeast(display_long)|uniprotkb:CKA2(gene name)|psi-mi:CKA2(display_short)|uniprotkb:YOR29-12(orf name)|uniprotkb:YOR061W(locus name) psi-mi:csk2c_yeast(display_long)|uniprotkb:CKB2(gene name)|psi-mi:CKB2(display_short)|uniprotkb:OR26.32(orf name)|uniprotkb:YOR039W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329896|imex:IM-14275-1452 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR061W(gene)|ensemblfungi:YOR061W_mRNA(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007535"(donor selection)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0034456"(UTP-C complex)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-2514853|reactome:R-SCE-6804756|reactome:R-SCE-8934903|reactome:R-SCE-8948751|refseq:NP_014704.1|sgd:S000005587|mint:P19454|dip:DIP-1038N ensemblfungi:YOR039W(gene)|ensemblfungi:YOR039W_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0032545"(CURI complex)|go:"GO:0034456"(UTP-C complex)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|reactome:R-SCE-2514853|reactome:R-SCE-6798695|reactome:R-SCE-6804756|reactome:R-SCE-8934903|reactome:R-SCE-8948751|refseq:NP_014682.1|sgd:S000005565|mint:P38930|dip:DIP-262N psi-mi:"MI:0469"(intact) crc64:30E214BD852824D0 crc64:D6060CB3D70B19A4 figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:E39eioYivVEqVSUhL99a2iGvisg559292 rogid:X+0JSYVQigL0wSbWYCkorc8jqpw559292 intact-crc:9CF07DAB12AD3220|rigid:qIOUgiWwfVanMOVztJlwK2hpVBA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43639 uniprotkb:P38930 intact:EBI-9563|uniprotkb:Q9URG5|ensemblfungi:YGL019W|uniprotkb:D6VUB8 intact:EBI-9578|ensemblfungi:YOR039W|uniprotkb:D6W2A6 psi-mi:csk2b_yeast(display_long)|uniprotkb:CKB1(gene name)|psi-mi:CKB1(display_short)|uniprotkb:YGL019W(locus name) psi-mi:csk2c_yeast(display_long)|uniprotkb:CKB2(gene name)|psi-mi:CKB2(display_short)|uniprotkb:OR26.32(orf name)|uniprotkb:YOR039W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329907|imex:IM-14275-1453 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL019W(gene)|ensemblfungi:YGL019W_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0034456"(UTP-C complex)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR035991|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|refseq:NP_011496.3|sgd:S000002987|mint:P43639|dip:DIP-282N ensemblfungi:YOR039W(gene)|ensemblfungi:YOR039W_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0032545"(CURI complex)|go:"GO:0034456"(UTP-C complex)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|reactome:R-SCE-2514853|reactome:R-SCE-6798695|reactome:R-SCE-6804756|reactome:R-SCE-8934903|reactome:R-SCE-8948751|refseq:NP_014682.1|sgd:S000005565|mint:P38930|dip:DIP-262N psi-mi:"MI:0469"(intact) crc64:9ACA8D285E6990AF crc64:D6060CB3D70B19A4 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:etfQ7p1F805HcUhV/Uiv9TPtejU559292 rogid:X+0JSYVQigL0wSbWYCkorc8jqpw559292 intact-crc:A621DEB5DF64C53F|rigid:kkQkXXfzttzNEY0BA5E94cRu2LY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:P38932 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-20444|uniprotkb:D6VU50|ensemblfungi:YGL095C psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:vps45_yeast(display_long)|uniprotkb:VPS45(gene name)|psi-mi:VPS45(display_short)|uniprotkb:STT10(gene name synonym)|uniprotkb:VPL28(gene name synonym)|uniprotkb:YGL095C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329918|imex:IM-14275-1454 author score:99.26 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 sgd:S000003063|refseq:NP_011420.3|ensemblfungi:YGL095C(gene)|ensemblfungi:YGL095C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007033"(vacuole organization)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0035543"(positive regulation of SNARE complex assembly)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|reactome:R-SCE-983231|dip:DIP-2693N|mint:P38932 psi-mi:"MI:0469"(intact) - crc64:4AA50D568228228F figure legend:tables S3 and S4|author-confidence:99.26|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:HSNdSBz2AD5AS/nSUjPV02ym8HQ559292 intact-crc:79C126AAD298F9BF|rigid:6X58862wfAn9zuHa6zFwiuTgsCg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07350 uniprotkb:P38954 intact:EBI-688|uniprotkb:Q05434|ensemblfungi:YDL043C|uniprotkb:D6VRV3 intact:EBI-9324|ensemblfungi:YDR072C|uniprotkb:D6VS58 psi-mi:prp11_yeast(display_long)|uniprotkb:PRP11(gene name)|psi-mi:PRP11(display_short)|uniprotkb:PRP10(gene name synonym)|uniprotkb:RNA11(gene name synonym)|uniprotkb:YDL043C(locus name)|uniprotkb:D2711(orf name) psi-mi:ipt1_yeast(display_long)|uniprotkb:IPT1(gene name)|psi-mi:IPT1(display_short)|uniprotkb:SYR4(gene name synonym)|uniprotkb:YDR072C(locus name)|uniprotkb:D4405(orf name)|uniprotkb:YD8554.05C(orf name)|uniprotkb:Mannosyl diphosphorylinositol ceramide synthase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329929|imex:IM-14275-1455 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010241.1|sgd:S000002201|ensemblfungi:YDL043C(gene)|ensemblfungi:YDL043C_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0008270"(zinc ion binding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR031781|interpro:IPR036236|rcsb pdb:4DGW|rcsb pdb:5GM6|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6G90|dip:DIP-1001N|mint:Q07350 ensemblfungi:YDR072C(gene)|go:"GO:0070916"(inositol phosphoceramide synthase complex)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR026841|ensemblfungi:YDR072C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0006676"(mannosyl diphosphorylinositol ceramide metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016772"(transferase activity, transferring phosphorus-containing groups)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0045140"(inositol phosphoceramide synthase activity)|refseq:NP_010357.3|sgd:S000002479|dip:DIP-5200N|mint:P38954 psi-mi:"MI:0469"(intact) crc64:D8BA3BB27F36F06F crc64:0792FE736A560BAE figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:xyunpB0FKbtjXifS4hyBHPmL4zs559292 rogid:9xO+5l6CpdxTEqvQybsY1p7IGXo559292 intact-crc:FC161843021E9B71|rigid:JtTugnndHt9gss/gT+eNKRwRx9A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38962 uniprotkb:Q04049 intact:EBI-22146|uniprotkb:D6VS71|ensemblfungi:YDR084C intact:EBI-36214|uniprotkb:D6VT49|ensemblfungi:YDR419W psi-mi:tvp23_yeast(display_long)|uniprotkb:TLG2 compartment vesicle protein of 23 kDa(gene name synonym)|uniprotkb:TVP23(gene name)|psi-mi:TVP23(display_short)|uniprotkb:YDR084C(locus name)|uniprotkb:D4466(orf name) psi-mi:polh_yeast(display_long)|uniprotkb:RAD30(gene name)|psi-mi:RAD30(display_short)|uniprotkb:DBH1(gene name synonym)|uniprotkb:YDR419W(locus name)|uniprotkb:Radiation-sensitive protein 30(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329940|imex:IM-14275-1456 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010369.3|sgd:S000002491|dip:DIP-1822N|mint:P38962|ensemblfungi:YDR084C(gene)|go:"GO:0030173"(integral component of Golgi membrane)|interpro:IPR008564(Protein of unknown function DUF846, eukaryotic)|ensemblfungi:YDR084C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport) sgd:S000002827|refseq:NP_010707.3|mint:Q04049|dip:DIP-6500N|ensemblfungi:YDR419W(gene)|ensemblfungi:YDR419W_mRNA(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0070987"(error-free translesion synthesis)|interpro:IPR001126(UMUC-like DNA-repair protein)|interpro:IPR036775|interpro:IPR041298|interpro:IPR043128|interpro:IPR043502|rcsb pdb:1JIH|rcsb pdb:2R8J|rcsb pdb:2R8K|rcsb pdb:2WTF|rcsb pdb:2XGP|rcsb pdb:2XGQ|rcsb pdb:3MFH|rcsb pdb:3MFI|rcsb pdb:3OHA|rcsb pdb:3OHB|rcsb pdb:5VTP|reactome:R-SCE-110320|reactome:R-SCE-5656169 psi-mi:"MI:0469"(intact) crc64:516BBCBB80F88BCF crc64:CFB1A9FBC8AFE39B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IgQg+TK8Pqo6rIEptKD4JU3g0YQ559292 rogid:UezH5s3d7XqG3y3LEglWvRzgzCc559292 intact-crc:D9AE947F7B781C8A|rigid:HqtDIJjKY1e/hsQXEIhhrrpaJBM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38986 uniprotkb:P38986 intact:EBI-3014|uniprotkb:D6VSV3|ensemblfungi:YDR321W intact:EBI-3014|uniprotkb:D6VSV3|ensemblfungi:YDR321W psi-mi:aspg1_yeast(display_long)|uniprotkb:YDR321W(locus name)|uniprotkb:D9798.6(orf name)|uniprotkb:ASP1(gene name)|psi-mi:ASP1(display_short)|uniprotkb:L-asparaginase I(gene name synonym)|uniprotkb:L-asparagine amidohydrolase I(gene name synonym) psi-mi:aspg1_yeast(display_long)|uniprotkb:YDR321W(locus name)|uniprotkb:D9798.6(orf name)|uniprotkb:ASP1(gene name)|psi-mi:ASP1(display_short)|uniprotkb:L-asparaginase I(gene name synonym)|uniprotkb:L-asparagine amidohydrolase I(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329951|imex:IM-14275-1457 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002729|refseq:NP_010607.3|dip:DIP-4030N|mint:P38986|ensemblfungi:YDR321W(gene)|ensemblfungi:YDR321W_mRNA(transcript)|go:"GO:0004067"(asparaginase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006530"(asparagine catabolic process)|go:"GO:0042597"(periplasmic space)|interpro:IPR004550(L-asparaginase, type II)|interpro:IPR006034(Asparaginase/glutaminase)|interpro:IPR020827|interpro:IPR027473|interpro:IPR027474|interpro:IPR027475|interpro:IPR036152|interpro:IPR037152|interpro:IPR040919 sgd:S000002729|refseq:NP_010607.3|dip:DIP-4030N|mint:P38986|ensemblfungi:YDR321W(gene)|ensemblfungi:YDR321W_mRNA(transcript)|go:"GO:0004067"(asparaginase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006530"(asparagine catabolic process)|go:"GO:0042597"(periplasmic space)|interpro:IPR004550(L-asparaginase, type II)|interpro:IPR006034(Asparaginase/glutaminase)|interpro:IPR020827|interpro:IPR027473|interpro:IPR027474|interpro:IPR027475|interpro:IPR036152|interpro:IPR037152|interpro:IPR040919 psi-mi:"MI:0469"(intact) crc64:8204CB7C58B5B75F crc64:8204CB7C58B5B75F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vIy3riBmCKfYQjsh3cIcO7o1Bzw559292 rogid:vIy3riBmCKfYQjsh3cIcO7o1Bzw559292 intact-crc:1EF9936500DBB91C|rigid:nFErsKj0Eq8Dgb0mGea+hV/v0/E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38988 uniprotkb:P25584 intact:EBI-24559|uniprotkb:D6VRF6|ensemblfungi:YDL198C intact:EBI-21765|uniprotkb:D6VQW1|ensemblfungi:YCL056C psi-mi:ggc1_yeast(display_long)|uniprotkb:GGC1(gene name)|psi-mi:GGC1(display_short)|uniprotkb:SHM1(gene name synonym)|uniprotkb:YDL198C(locus name)|uniprotkb:D1214(orf name)|uniprotkb:YHM1(gene name synonym) psi-mi:pex34_yeast(display_long)|uniprotkb:YCL056C(locus name)|uniprotkb:YCL56C(orf name)|uniprotkb:YCL433(orf name)|uniprotkb:PEX34(gene name)|psi-mi:PEX34(display_short)|uniprotkb:Peroxin-34(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329962|imex:IM-14275-1458 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010083.1|sgd:S000002357|dip:DIP-7756N|mint:P38988|ensemblfungi:YDL198C(gene)|ensemblfungi:YDL198C_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001408"(guanine nucleotide transport)|go:"GO:0001409"(guanine nucleotide transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|interpro:IPR018108|interpro:IPR023395 sgd:S000000561|refseq:NP_009875.1|mint:P25584|dip:DIP-2040N|ensemblfungi:YCL056C(gene)|ensemblfungi:YCL056C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization) psi-mi:"MI:0469"(intact) - crc64:6035D449766516A6 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FHknYM2avGc4qOGauYRFeTgf4xA559292 rogid:IGoLOZeCbBNA4w+BG9mC/vxGfqs559292 intact-crc:37E2D2D3F6E9A7C6|rigid:fGYErDnB/cAegB+MXlzzACXlTSQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38988 uniprotkb:P52490 intact:EBI-24559|uniprotkb:D6VRF6|ensemblfungi:YDL198C intact:EBI-19777|uniprotkb:D6VS79|ensemblfungi:YDR092W psi-mi:ggc1_yeast(display_long)|uniprotkb:GGC1(gene name)|psi-mi:GGC1(display_short)|uniprotkb:SHM1(gene name synonym)|uniprotkb:YDL198C(locus name)|uniprotkb:D1214(orf name)|uniprotkb:YHM1(gene name synonym) psi-mi:ubc13_yeast(display_long)|uniprotkb:UBC13(gene name)|psi-mi:UBC13(display_short)|uniprotkb:YDR092W(locus name)|uniprotkb:YD6652.04(orf name)|uniprotkb:Ubiquitin-protein ligase 13(gene name synonym)|uniprotkb:Ubiquitin carrier protein 13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 13(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329973|imex:IM-14275-1459 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010083.1|sgd:S000002357|dip:DIP-7756N|mint:P38988|ensemblfungi:YDL198C(gene)|ensemblfungi:YDL198C_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001408"(guanine nucleotide transport)|go:"GO:0001409"(guanine nucleotide transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|interpro:IPR018108|interpro:IPR023395 sgd:S000002499|ensemblfungi:YDR092W(gene)|ensemblfungi:YDR092W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006301"(postreplication repair)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0044395"(protein targeting to vacuolar membrane)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1JAT|rcsb pdb:1JBB|rcsb pdb:2GMI|rcsb pdb:4FH1|rcsb pdb:5OJW|reactome:R-SCE-8866654|reactome:R-SCE-9020702|reactome:R-SCE-9646399|reactome:R-SCE-983168|refseq:NP_010377.3|dip:DIP-5486N|mint:P52490 psi-mi:"MI:0469"(intact) - crc64:445558F8F193275B figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FHknYM2avGc4qOGauYRFeTgf4xA559292 rogid:5nTtjUZ2IpzHhrj1UU6NlaRW53k559292 intact-crc:2E4754D49B48C113|rigid:IhC0+Xt5w/N60St/A6u3Pe+nIlY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38988 uniprotkb:Q07500 intact:EBI-24559|uniprotkb:D6VRF6|ensemblfungi:YDL198C intact:EBI-38178|uniprotkb:D6VRR4|ensemblfungi:YDL085W psi-mi:ggc1_yeast(display_long)|uniprotkb:GGC1(gene name)|psi-mi:GGC1(display_short)|uniprotkb:SHM1(gene name synonym)|uniprotkb:YDL198C(locus name)|uniprotkb:D1214(orf name)|uniprotkb:YHM1(gene name synonym) psi-mi:ndh2_yeast(display_long)|uniprotkb:NDE2(gene name)|psi-mi:NDE2(display_short)|uniprotkb:NDH2(gene name synonym)|uniprotkb:YDL085W(locus name)|uniprotkb:External NADH dehydrogenase 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329984|imex:IM-14275-1460 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010083.1|sgd:S000002357|dip:DIP-7756N|mint:P38988|ensemblfungi:YDL198C(gene)|ensemblfungi:YDL198C_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001408"(guanine nucleotide transport)|go:"GO:0001409"(guanine nucleotide transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|interpro:IPR018108|interpro:IPR023395 refseq:NP_010198.1|sgd:S000002243|mint:Q07500|dip:DIP-5023N|ensemblfungi:YDL085W(gene)|ensemblfungi:YDL085W_mRNA(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006116"(NADH oxidation)|go:"GO:0019655"(glycolytic fermentation to ethanol)|go:"GO:0050136"("NADH dehydrogenase (quinone) activity")|interpro:IPR023753|interpro:IPR036188 psi-mi:"MI:0469"(intact) - crc64:291E81D0FC6D3FD7 figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FHknYM2avGc4qOGauYRFeTgf4xA559292 rogid:VDKbGYjFURtBVpghiIp4aKVVAfI559292 intact-crc:3E3D8205AA41924C|rigid:Xo5QLnXx0ChBbnkP5b/Ho/weU4U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P38992 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-18574|ensemblfungi:YDR297W|uniprotkb:D6VSS6 psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:sur2_yeast(display_long)|uniprotkb:SUR2(gene name)|psi-mi:SUR2(display_short)|uniprotkb:SYR2(gene name synonym)|uniprotkb:YDR297W(locus name)|uniprotkb:D9740.8(orf name)|uniprotkb:Syringomycin response protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6329995|imex:IM-14275-1461 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0042284"(sphingolipid delta-4 desaturase activity)|interpro:IPR006694(Fatty acid hydroxylase)|go:"GO:0006665"(sphingolipid metabolic process)|ensemblfungi:YDR297W(gene)|ensemblfungi:YDR297W_mRNA(transcript)|go:"GO:0000170"(sphingosine hydroxylase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|refseq:NP_010583.1|sgd:S000002705|dip:DIP-7741N|mint:P38992 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:HcXW6Nko6+g+16d/ehjh8p2sl8Y559292 intact-crc:C991551136DD7903|rigid:tR/5lsJVAFhzxax6EJL3rw/2q/g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38992 uniprotkb:P26570 intact:EBI-18574|ensemblfungi:YDR297W|uniprotkb:D6VSS6 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 psi-mi:sur2_yeast(display_long)|uniprotkb:SUR2(gene name)|psi-mi:SUR2(display_short)|uniprotkb:SYR2(gene name synonym)|uniprotkb:YDR297W(locus name)|uniprotkb:D9740.8(orf name)|uniprotkb:Syringomycin response protein 2(gene name synonym) psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330006|imex:IM-14275-1462 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0042284"(sphingolipid delta-4 desaturase activity)|interpro:IPR006694(Fatty acid hydroxylase)|go:"GO:0006665"(sphingolipid metabolic process)|ensemblfungi:YDR297W(gene)|ensemblfungi:YDR297W_mRNA(transcript)|go:"GO:0000170"(sphingosine hydroxylase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|refseq:NP_010583.1|sgd:S000002705|dip:DIP-7741N|mint:P38992 ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N psi-mi:"MI:0469"(intact) - crc64:8B7F009521F72C15 figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HcXW6Nko6+g+16d/ehjh8p2sl8Y559292 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 intact-crc:5125F2647A09D152|rigid:OgIM0oV6+6yqcIIjZPtBnWwCLRk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38992 uniprotkb:P36076 intact:EBI-18574|ensemblfungi:YDR297W|uniprotkb:D6VSS6 intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W psi-mi:sur2_yeast(display_long)|uniprotkb:SUR2(gene name)|psi-mi:SUR2(display_short)|uniprotkb:SYR2(gene name synonym)|uniprotkb:YDR297W(locus name)|uniprotkb:D9740.8(orf name)|uniprotkb:Syringomycin response protein 2(gene name synonym) psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330017|imex:IM-14275-1463 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0042284"(sphingolipid delta-4 desaturase activity)|interpro:IPR006694(Fatty acid hydroxylase)|go:"GO:0006665"(sphingolipid metabolic process)|ensemblfungi:YDR297W(gene)|ensemblfungi:YDR297W_mRNA(transcript)|go:"GO:0000170"(sphingosine hydroxylase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|refseq:NP_010583.1|sgd:S000002705|dip:DIP-7741N|mint:P38992 refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HcXW6Nko6+g+16d/ehjh8p2sl8Y559292 rogid:Li7vZOassm4PC5fW111/j5ivgEc559292 intact-crc:3DC83F5095BAC845|rigid:kWyiTVal4uebTv7fGxOr7D3y9MQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38992 uniprotkb:P38264 intact:EBI-18574|ensemblfungi:YDR297W|uniprotkb:D6VSS6 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 psi-mi:sur2_yeast(display_long)|uniprotkb:SUR2(gene name)|psi-mi:SUR2(display_short)|uniprotkb:SYR2(gene name synonym)|uniprotkb:YDR297W(locus name)|uniprotkb:D9740.8(orf name)|uniprotkb:Syringomycin response protein 2(gene name synonym) psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330028|imex:IM-14275-1464 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0042284"(sphingolipid delta-4 desaturase activity)|interpro:IPR006694(Fatty acid hydroxylase)|go:"GO:0006665"(sphingolipid metabolic process)|ensemblfungi:YDR297W(gene)|ensemblfungi:YDR297W_mRNA(transcript)|go:"GO:0000170"(sphingosine hydroxylase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|refseq:NP_010583.1|sgd:S000002705|dip:DIP-7741N|mint:P38992 refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HcXW6Nko6+g+16d/ehjh8p2sl8Y559292 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 intact-crc:DE8190B7E3DDC5CE|rigid:0qGIfUnSkWRbKAfGgYVYmCYH1ak false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38992 uniprotkb:P54837 intact:EBI-18574|ensemblfungi:YDR297W|uniprotkb:D6VSS6 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:sur2_yeast(display_long)|uniprotkb:SUR2(gene name)|psi-mi:SUR2(display_short)|uniprotkb:SYR2(gene name synonym)|uniprotkb:YDR297W(locus name)|uniprotkb:D9740.8(orf name)|uniprotkb:Syringomycin response protein 2(gene name synonym) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330039|imex:IM-14275-1465 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0042284"(sphingolipid delta-4 desaturase activity)|interpro:IPR006694(Fatty acid hydroxylase)|go:"GO:0006665"(sphingolipid metabolic process)|ensemblfungi:YDR297W(gene)|ensemblfungi:YDR297W_mRNA(transcript)|go:"GO:0000170"(sphingosine hydroxylase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|refseq:NP_010583.1|sgd:S000002705|dip:DIP-7741N|mint:P38992 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HcXW6Nko6+g+16d/ehjh8p2sl8Y559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:0B0B88C869F0F750|rigid:fNkijGQ7sWOWuXTXleHXl/wNLSg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38992 uniprotkb:Q02774 intact:EBI-18574|ensemblfungi:YDR297W|uniprotkb:D6VSS6 intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 psi-mi:sur2_yeast(display_long)|uniprotkb:SUR2(gene name)|psi-mi:SUR2(display_short)|uniprotkb:SYR2(gene name synonym)|uniprotkb:YDR297W(locus name)|uniprotkb:D9740.8(orf name)|uniprotkb:Syringomycin response protein 2(gene name synonym) psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330050|imex:IM-14275-1466 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0042284"(sphingolipid delta-4 desaturase activity)|interpro:IPR006694(Fatty acid hydroxylase)|go:"GO:0006665"(sphingolipid metabolic process)|ensemblfungi:YDR297W(gene)|ensemblfungi:YDR297W_mRNA(transcript)|go:"GO:0000170"(sphingosine hydroxylase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|refseq:NP_010583.1|sgd:S000002705|dip:DIP-7741N|mint:P38992 refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HcXW6Nko6+g+16d/ehjh8p2sl8Y559292 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 intact-crc:DCC15803118058D2|rigid:u/0UgsApgM+L3ofNDw/8RvUNNEY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38992 uniprotkb:Q05359 intact:EBI-18574|ensemblfungi:YDR297W|uniprotkb:D6VSS6 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A psi-mi:sur2_yeast(display_long)|uniprotkb:SUR2(gene name)|psi-mi:SUR2(display_short)|uniprotkb:SYR2(gene name synonym)|uniprotkb:YDR297W(locus name)|uniprotkb:D9740.8(orf name)|uniprotkb:Syringomycin response protein 2(gene name synonym) psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330061|imex:IM-14275-1467 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0042284"(sphingolipid delta-4 desaturase activity)|interpro:IPR006694(Fatty acid hydroxylase)|go:"GO:0006665"(sphingolipid metabolic process)|ensemblfungi:YDR297W(gene)|ensemblfungi:YDR297W_mRNA(transcript)|go:"GO:0000170"(sphingosine hydroxylase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|refseq:NP_010583.1|sgd:S000002705|dip:DIP-7741N|mint:P38992 refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HcXW6Nko6+g+16d/ehjh8p2sl8Y559292 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 intact-crc:11929CE0C3E500E6|rigid:hD/F4VeVXkv1cr+/77RkNz3coBk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38992 uniprotkb:Q06144 intact:EBI-18574|ensemblfungi:YDR297W|uniprotkb:D6VSS6 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:sur2_yeast(display_long)|uniprotkb:SUR2(gene name)|psi-mi:SUR2(display_short)|uniprotkb:SYR2(gene name synonym)|uniprotkb:YDR297W(locus name)|uniprotkb:D9740.8(orf name)|uniprotkb:Syringomycin response protein 2(gene name synonym) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330072|imex:IM-14275-1468 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0042284"(sphingolipid delta-4 desaturase activity)|interpro:IPR006694(Fatty acid hydroxylase)|go:"GO:0006665"(sphingolipid metabolic process)|ensemblfungi:YDR297W(gene)|ensemblfungi:YDR297W_mRNA(transcript)|go:"GO:0000170"(sphingosine hydroxylase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|refseq:NP_010583.1|sgd:S000002705|dip:DIP-7741N|mint:P38992 refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:2F474503CAB7C195 figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HcXW6Nko6+g+16d/ehjh8p2sl8Y559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 intact-crc:523B1256AD36009E|rigid:Xqw+Mf+75VaR5/2k4CRqRQzDJB4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39002 uniprotkb:P54783 intact:EBI-10089|uniprotkb:D6VVS1|ensemblfungi:YIL009W intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:lcf3_yeast(display_long)|uniprotkb:YIL009W(locus name)|uniprotkb:FAA3(gene name)|psi-mi:FAA3(display_short)|uniprotkb:Long-chain acyl-CoA synthetase 3(gene name synonym)|uniprotkb:Fatty acid activator 3(gene name synonym) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330084|imex:IM-14275-1469 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012257.1|sgd:S000001271|ensemblfungi:YIL009W(gene)|ensemblfungi:YIL009W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0035336"(long-chain fatty-acyl-CoA metabolic process)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-SCE-434313|reactome:R-SCE-75876|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|dip:DIP-4210N|mint:P39002 go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iZQtnX6WYI6klt+mdCytjXaptpQ559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:CACD4292ECD4012E|rigid:BQ4N0lFZx3BdVi0MBDJk5b+l26U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02785 uniprotkb:P39002 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C intact:EBI-10089|uniprotkb:D6VVS1|ensemblfungi:YIL009W psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:lcf3_yeast(display_long)|uniprotkb:YIL009W(locus name)|uniprotkb:FAA3(gene name)|psi-mi:FAA3(display_short)|uniprotkb:Long-chain acyl-CoA synthetase 3(gene name synonym)|uniprotkb:Fatty acid activator 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330095|imex:IM-14275-1470 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) refseq:NP_012257.1|sgd:S000001271|ensemblfungi:YIL009W(gene)|ensemblfungi:YIL009W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0035336"(long-chain fatty-acyl-CoA metabolic process)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-SCE-434313|reactome:R-SCE-75876|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|dip:DIP-4210N|mint:P39002 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 rogid:iZQtnX6WYI6klt+mdCytjXaptpQ559292 intact-crc:0F1830FCD6D58EBD|rigid:rroIBV06MNFQOK6hKlH+R/0kveI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39002 uniprotkb:Q06451 intact:EBI-10089|uniprotkb:D6VVS1|ensemblfungi:YIL009W intact:EBI-34275|uniprotkb:D6W4F2|ensemblfungi:YPR156C psi-mi:lcf3_yeast(display_long)|uniprotkb:YIL009W(locus name)|uniprotkb:FAA3(gene name)|psi-mi:FAA3(display_short)|uniprotkb:Long-chain acyl-CoA synthetase 3(gene name synonym)|uniprotkb:Fatty acid activator 3(gene name synonym) psi-mi:tpo3_yeast(display_long)|uniprotkb:TPO3(gene name)|psi-mi:TPO3(display_short)|uniprotkb:P9584.7(orf name)|uniprotkb:YPR156C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330106|imex:IM-14275-1471 author score:99.24 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012257.1|sgd:S000001271|ensemblfungi:YIL009W(gene)|ensemblfungi:YIL009W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0035336"(long-chain fatty-acyl-CoA metabolic process)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|reactome:R-SCE-434313|reactome:R-SCE-75876|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|dip:DIP-4210N|mint:P39002 refseq:NP_015482.1|sgd:S000006360|mint:Q06451|dip:DIP-3907N|ensemblfungi:YPR156C(gene)|ensemblfungi:YPR156C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - crc64:D260ED161F800502 figure legend:tables S3 and S4|author-confidence:99.24|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iZQtnX6WYI6klt+mdCytjXaptpQ559292 rogid:oVpx7Bjk/mK2Q7+/j05tX3gHw7k559292 intact-crc:6028ED1F37DF86B0|rigid:WgD32zoBsgE66i2BF/q/dxYipPk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06102 uniprotkb:P39008 intact:EBI-12165|uniprotkb:D6VVP4|uniprotkb:Q6B233|ensemblfungi:YIL038C intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C psi-mi:not3_yeast(display_long)|uniprotkb:NOT3(gene name)|psi-mi:NOT3(display_short)|uniprotkb:YIL038C(locus name) psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330117|imex:IM-14275-1472 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR038635|interpro:IPR040168|ensemblfungi:YIL038C(gene)|ensemblfungi:YIL038C_mRNA(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|refseq:NP_012226.3|sgd:S000001300|dip:DIP-2256N|mint:P06102 sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N psi-mi:"MI:0469"(intact) crc64:69B76694FCC6846F crc64:F3CAF97106A65933 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:EfakZPDNU3FZeI5+rnu7YV1UsCg559292 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 intact-crc:78BB22A244364C21|rigid:z5nmTsDHKKJMa+mcDV2TnS4ohA0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25655 uniprotkb:P39008 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330128|imex:IM-14275-1473 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N psi-mi:"MI:0469"(intact) crc64:5B2AE15BCF95E009 crc64:F3CAF97106A65933 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 intact-crc:3CAAC9C0A20D25B4|rigid:4HSUcQXMUkpB6qlyKvwZlmBucnc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34761 uniprotkb:P39008 intact:EBI-20537|uniprotkb:D6W0Z0|ensemblfungi:YNL197C intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C psi-mi:whi3_yeast(display_long)|uniprotkb:WHI3(gene name)|psi-mi:WHI3(display_short)|uniprotkb:N1382(orf name)|uniprotkb:YNL197C(locus name) psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330139|imex:IM-14275-1474 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014202.1|sgd:S000005141|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|ensemblfungi:YNL197C(gene)|ensemblfungi:YNL197C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0032106"(positive regulation of response to extracellular stimulus)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0061013"(regulation of mRNA catabolic process)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071554"(cell wall organization or biogenesis)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P34761 sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N psi-mi:"MI:0469"(intact) - crc64:F3CAF97106A65933 figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Xpn0uJiaylcupy9qYDLa0V++z6A559292 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 intact-crc:F5A5B95C3A9877D4|rigid:vR+dc3/fCBHPx+cw66AVEcDyATM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34909 uniprotkb:P39008 intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330150|imex:IM-14275-1475 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N psi-mi:"MI:0469"(intact) crc64:8847084BD9BF48B7 crc64:F3CAF97106A65933 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 intact-crc:EFFBF779CB55C44C|rigid:ToyRSMSjkf1SvrGd9BKHypBDGP4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35732 uniprotkb:P39008 intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330161|imex:IM-14275-1476 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N psi-mi:"MI:0469"(intact) crc64:05734E2D0B7389AC crc64:F3CAF97106A65933 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 intact-crc:D9BE5630EAEA4456|rigid:X+25jmd8ZL1DkcT97Z3KY5DW17s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39008 uniprotkb:P53829 intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330172|imex:IM-14275-1477 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 psi-mi:"MI:0469"(intact) crc64:F3CAF97106A65933 crc64:F3DBABE6AD3C7F3C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 intact-crc:423562F52337D36C|rigid:9Aa39iMdYZHr97bGe+lv5BcKASg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39008 uniprotkb:P53935 intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C intact:EBI-28788|uniprotkb:Q45TZ3|uniprotkb:D6W189|ensemblfungi:YNL091W psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:nst1_yeast(display_long)|uniprotkb:YNL091W(locus name)|uniprotkb:N2231(orf name)|uniprotkb:NST1(gene name)|psi-mi:NST1(display_short)|uniprotkb:Negatively-affecting salt tolerance protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330183|imex:IM-14275-1478 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N refseq:NP_014308.1|sgd:S000005035|dip:DIP-872N|mint:P53935|ensemblfungi:YNL091W(gene)|ensemblfungi:YNL091W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009651"(response to salt stress)|interpro:IPR025279 psi-mi:"MI:0469"(intact) crc64:F3CAF97106A65933 - figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 rogid:WOSVMqWhtYPlZyt+vfdkpJAHHBg559292 intact-crc:0F17F1EEB7F78932|rigid:tjh7+485L68nMe9OktFyYHA/Qu8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:P39010 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330194|imex:IM-14275-1479 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 intact-crc:6E6D12BE3E2781D9|rigid:r4jVTouQUEp3nkkER8F1zT1D3nA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39010 uniprotkb:P11076 intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330205|imex:IM-14275-1480 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 psi-mi:"MI:0469"(intact) - crc64:796859026AC63CC0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 intact-crc:3CA1D142C661E556|rigid:rn54wm4nBxbzznxczuIVwLUUyog false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39010 uniprotkb:P23291 intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C intact:EBI-4718|uniprotkb:E9P958|uniprotkb:D3DL84|ensemblfungi:YHR135C psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:kc11_yeast(display_long)|uniprotkb:YCK1(gene name)|psi-mi:YCK1(display_short)|uniprotkb:CKI2(gene name synonym)|uniprotkb:YHR135C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330216|imex:IM-14275-1481 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 refseq:NP_012003.1|sgd:S000001177|dip:DIP-719N|mint:P23291|ensemblfungi:YHR135C(gene)|ensemblfungi:YHR135C_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0009749"(response to glucose)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:5X18 psi-mi:"MI:0469"(intact) - crc64:77344717818C2D17 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 rogid:pFpwRNbvvNZ1NPc7VMVXSivwMeI559292 intact-crc:F5074DCE6960868F|rigid:81B90tsG/lHKIUZWSRS68Mz1tp4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39010 uniprotkb:P25361 intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C intact:EBI-21909|uniprotkb:D6VR52|ensemblfungi:YCR043C psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:yct3_yeast(display_long)|uniprotkb:YCR43C(orf name)|uniprotkb:YCR725(orf name)|uniprotkb:YCR043C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330227|imex:IM-14275-1482 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 sgd:S000000639|refseq:NP_009972.1|mint:P25361|ensemblfungi:YCR043C(gene)|ensemblfungi:YCR043C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0043332"(mating projection tip) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 rogid:bEMtsAa5vCsWqGOiXwBK40Pa0xQ559292 intact-crc:80CCCCE853BD8072|rigid:Xs8iTVVDBxRj9CNqkB5Ui48bE+s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36164 uniprotkb:P39010 intact:EBI-26527|uniprotkb:D6VXE8|ensemblfungi:YKR088C intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C psi-mi:tvp38_yeast(display_long)|uniprotkb:YKR408(orf name)|uniprotkb:YKR088C(locus name)|uniprotkb:TVP38(gene name)|psi-mi:TVP38(display_short)|uniprotkb:TLG2-vesicle protein of 38 kDa(gene name synonym) psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330238|imex:IM-14275-1483 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001796|refseq:NP_013014.3|mint:P36164|dip:DIP-5167N|interpro:IPR032816|ensemblfungi:YKR088C(gene)|ensemblfungi:YKR088C_mRNA(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0005737"(cytoplasm)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane) refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 psi-mi:"MI:0469"(intact) crc64:7EA95DD4E5AF77FE - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wNtRh3eKqVkQKwO9QmrJHjSSdnk559292 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 intact-crc:81A142D27A2B0E08|rigid:uzoPNlOYxQfxdVfFd6PZ6mi5zyc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39010 uniprotkb:P38142 intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C intact:EBI-21079|uniprotkb:D6VQN7|intact:EBI-2347460|uniprotkb:Q6B2Y5|ensemblfungi:YBR241C psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:yb91_yeast(display_long)|uniprotkb:YBR1625(orf name)|uniprotkb:YBR241C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330249|imex:IM-14275-1484 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 refseq:NP_009800.1|sgd:S000000445|mint:P38142|dip:DIP-5363N|ensemblfungi:YBR241C(gene)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|reactome:R-SCE-189200|reactome:R-SCE-196836|reactome:R-SCE-422356|reactome:R-SCE-5653890|reactome:R-SCE-6798695|reactome:R-SCE-8981373|ensemblfungi:YBR241C_mRNA(transcript) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 rogid:B0qgnhfd17hrDGLrJ21KY/FCzTQ559292 intact-crc:FA925A87FC4492D0|rigid:vzEUPBnD9AJET0VPhpUNwnSJSqY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39010 uniprotkb:P38166 intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330260|imex:IM-14275-1485 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166 psi-mi:"MI:0469"(intact) - crc64:1BF971749814382C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292 intact-crc:205DD9F500D800E8|rigid:FkLF0X66mYuMjrrKvetgVEiXA0c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39010 uniprotkb:P39010 intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330271|imex:IM-14275-1486 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 intact-crc:98AAADB78E96B0E7|rigid:JbSG1qm6fkeEq3VsTWYF2IeP+HY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39010 uniprotkb:P40094 intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C intact:EBI-16605|ensemblfungi:YER157W|uniprotkb:D3DM64 psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:cog3_yeast(display_long)|uniprotkb:COG3(gene name)|psi-mi:COG3(display_short)|uniprotkb:GRD20(gene name synonym)|uniprotkb:SEC34(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 3(gene name synonym)|uniprotkb:Protein SEC34(gene name synonym)|uniprotkb:YER157W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330282|imex:IM-14275-1487 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 ensemblfungi:YER157W(gene)|ensemblfungi:YER157W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR007265(Sec34-like protein)|refseq:NP_011084.1|sgd:S000000959|dip:DIP-4728N|mint:P40094 psi-mi:"MI:0469"(intact) - crc64:C7AFBE99010FE571 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 rogid:R2r0ZW+nxrykdTHq1cJy9zOmvHo559292 intact-crc:3B78ACB2C7154DBE|rigid:nceMRJ8OH6uQWPPv0s8KO7lDo6c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40527 uniprotkb:P39010 intact:EBI-3137|uniprotkb:D6VVN3|ensemblfungi:YIL048W intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C psi-mi:atc7_yeast(display_long)|uniprotkb:NEO1(gene name)|psi-mi:NEO1(display_short)|uniprotkb:YIL048W(locus name) psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330293|imex:IM-14275-1488 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012216.1|sgd:S000001310|dip:DIP-2548N|mint:P40527|ensemblfungi:YIL048W(gene)|ensemblfungi:YIL048W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006897"(endocytosis)|go:"GO:0007033"(vacuole organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-936837 refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:v12VeCVbehsVpj+kjnnhKmIf9o4559292 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 intact-crc:60B84661DDD6A376|rigid:043QrODbaE/Yl0ncE7f2r2uofM4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43621 uniprotkb:P39010 intact:EBI-4876|uniprotkb:D6VTT4|ensemblfungi:YFR051C intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C psi-mi:copd_yeast(display_long)|uniprotkb:RET2(gene name)|psi-mi:RET2(display_short)|uniprotkb:YFR051C(locus name)|uniprotkb:Delta-coat protein(gene name synonym) psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330304|imex:IM-14275-1489 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001947|refseq:NP_116709.3|dip:DIP-5255N|mint:P43621|ensemblfungi:YFR051C(gene)|ensemblfungi:YFR051C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|rcsb pdb:5FJW|rcsb pdb:5FJX|rcsb pdb:5FJZ|rcsb pdb:5FK0|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 psi-mi:"MI:0469"(intact) crc64:AA730F046655EE5A - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:auvjuT8ffm1R4P3mRKEIWAsynW0559292 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 intact-crc:D01EBA3EDFB862FE|rigid:DbgaeFdrMjTjI46bzPnUlEOl7GM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39010 uniprotkb:P46989 intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330315|imex:IM-14275-1490 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 intact-crc:52EA2C56B89AB2CA|rigid:iVQiTjumL5ysAEIIIwWb+tcd5K4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54858 uniprotkb:P39010 intact:EBI-6042|uniprotkb:D6VS54|ensemblfungi:YDR068W intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C psi-mi:dos2_yeast(display_long)|uniprotkb:D4267(orf name)|uniprotkb:YD8554.01(orf name)|uniprotkb:YD9609.22(orf name)|uniprotkb:DOS2(gene name)|psi-mi:DOS2(display_short)|uniprotkb:YDR068W(locus name) psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330326|imex:IM-14275-1491 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002475|refseq:NP_010353.3|dip:DIP-4785N|mint:P54858|ensemblfungi:YDR068W(gene)|ensemblfungi:YDR068W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR005607(BSD)|interpro:IPR035925 refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:/4fnAAPmC12DMUbUB8MVS9yjjeg559292 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 intact-crc:E24FF059347A09D2|rigid:rBt/gm6cVkyHoHJ36OVn26cacg8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39010 uniprotkb:Q03687 intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330337|imex:IM-14275-1492 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 intact-crc:0DE52A8F515E78D9|rigid:2wQJgMJ0EtOujfLg6RNYPm6e5/A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39010 uniprotkb:Q03860 intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330348|imex:IM-14275-1493 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) - crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:E79B79402E858BDB|rigid:BMRnPQRcxUweGt3XZhHuEEDpUL4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39010 uniprotkb:Q08280 intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C intact:EBI-35858|uniprotkb:Q6B229|uniprotkb:D6W1T2|ensemblfungi:YOL137W psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:bsc6_yeast(display_long)|uniprotkb:YOL137W(locus name)|uniprotkb:BSC6(gene name)|psi-mi:BSC6(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330359|imex:IM-14275-1494 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 refseq:NP_014504.1|sgd:S000005497|mint:Q08280|dip:DIP-4683N|ensemblfungi:YOL137W(gene)|ensemblfungi:YOL137W_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 rogid:WVYZke8YJvNcS4D9bUnthAFdq3A559292 intact-crc:03B41C84874F2FE7|rigid:L9NRfEaPLNRwwqpsFizRS+l8kA4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39010 uniprotkb:Q12057 intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C intact:EBI-29838|uniprotkb:D6W2G4|ensemblfungi:YOR104W psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:pin2_yeast(display_long)|uniprotkb:PIN2(gene name)|psi-mi:PIN2(display_short)|uniprotkb:YOR3214W(orf name)|uniprotkb:YOR104W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330370|imex:IM-14275-1495 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 sgd:S000005630|refseq:NP_014747.1|dip:DIP-4459N|mint:Q12057|ensemblfungi:YOR104W(gene)|ensemblfungi:YOR104W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|interpro:IPR037504 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 rogid:Zk6iUcpP++MEXuhKZ79TMOYQYqM559292 intact-crc:FE8C47190A850E36|rigid:xsKxuhgprUbkHyh74UPQGVlt1qk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:P39010 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330381|imex:IM-14275-1496 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 intact-crc:5CBC6CFFA16F36CC|rigid:VkjEuMHQIt7fUvF+SXnnvXTeBpc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6Q5X2 uniprotkb:P39010 intact:EBI-2043695|uniprotkb:D6VS22|ensemblfungi:YDR034W-B intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C psi-mi:yd34b_yeast(display_long)|uniprotkb:YDR034W-B(locus name) psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330392|imex:IM-14275-1497 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000007234|refseq:NP_010319.3|interpro:IPR028144|mint:Q6Q5X2|ensemblfungi:YDR034W-B(gene)|ensemblfungi:YDR034W-B_mRNA(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery) refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Q0HaYjXrSQxQGjBDwholuxLeSRo559292 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 intact-crc:AE6ED9858625D9B5|rigid:LjpfYPo8so32YX4xDwy0lZIDuxA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38875 uniprotkb:P39012 intact:EBI-24869|uniprotkb:D3DLD6|ensemblfungi:YHR188C intact:EBI-7252|uniprotkb:D6VY88|ensemblfungi:YLR088W psi-mi:gpi16_yeast(display_long)|uniprotkb:GPI16(gene name)|psi-mi:GPI16(display_short)|uniprotkb:YHR188C(locus name) psi-mi:gaa1_yeast(display_long)|uniprotkb:GAA1(gene name)|psi-mi:GAA1(display_short)|uniprotkb:END2(gene name synonym)|uniprotkb:YLR088W(locus name)|uniprotkb:L9449.4(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330403|imex:IM-14275-1498 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012058.1|sgd:S000001231|mint:P38875|dip:DIP-1888N|ensemblfungi:YHR188C(gene)|ensemblfungi:YHR188C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component) refseq:NP_013189.1|sgd:S000004078|mint:P39012|dip:DIP-4824N|ensemblfungi:YLR088W(gene)|ensemblfungi:YLR088W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR007246(Gaa1-like, GPI transamidase component) psi-mi:"MI:0469"(intact) crc64:E9613CE0EA99F963 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:qvK2gNcnfXW5KU81xOCtdz54jgI559292 rogid:amv3rxKpKmjGpnjzMInYFQXvlUg559292 intact-crc:BADAA6B488263BAA|rigid:9HL+9mba9UsX74TUykTzwGeQaNM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P49018 uniprotkb:P39012 intact:EBI-7822|uniprotkb:D6VSW3|ensemblfungi:YDR331W intact:EBI-7252|uniprotkb:D6VY88|ensemblfungi:YLR088W psi-mi:gpi8_yeast(display_long)|uniprotkb:GPI8(gene name)|psi-mi:GPI8(display_short)|uniprotkb:D9798.2(orf name)|uniprotkb:YDR331W(locus name) psi-mi:gaa1_yeast(display_long)|uniprotkb:GAA1(gene name)|psi-mi:GAA1(display_short)|uniprotkb:END2(gene name synonym)|uniprotkb:YLR088W(locus name)|uniprotkb:L9449.4(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330414|imex:IM-14275-1499 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010618.1|sgd:S000002739|dip:DIP-5371N|mint:P49018|ensemblfungi:YDR331W(gene)|ensemblfungi:YDR331W_mRNA(transcript)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361 refseq:NP_013189.1|sgd:S000004078|mint:P39012|dip:DIP-4824N|ensemblfungi:YLR088W(gene)|ensemblfungi:YLR088W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR007246(Gaa1-like, GPI transamidase component) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5h/ZRVpqdt/EC4pSAd0qlKcUZUk559292 rogid:amv3rxKpKmjGpnjzMInYFQXvlUg559292 intact-crc:E2ECC83945E84336|rigid:tlnEQS2oj0buMU0fmWL4T0XWVEI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04080 uniprotkb:P39012 intact:EBI-7777|uniprotkb:D6VT61|ensemblfungi:YDR434W intact:EBI-7252|uniprotkb:D6VY88|ensemblfungi:YLR088W psi-mi:gpi17_yeast(display_long)|uniprotkb:GPI17(gene name)|psi-mi:GPI17(display_short)|uniprotkb:D9461.20(orf name)|uniprotkb:YDR434W(locus name) psi-mi:gaa1_yeast(display_long)|uniprotkb:GAA1(gene name)|psi-mi:GAA1(display_short)|uniprotkb:END2(gene name synonym)|uniprotkb:YLR088W(locus name)|uniprotkb:L9449.4(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330425|imex:IM-14275-1500 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002842|interpro:IPR019540|refseq:NP_010722.3|mint:Q04080|ensemblfungi:YDR434W(gene)|ensemblfungi:YDR434W_mRNA(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex) refseq:NP_013189.1|sgd:S000004078|mint:P39012|dip:DIP-4824N|ensemblfungi:YLR088W(gene)|ensemblfungi:YLR088W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR007246(Gaa1-like, GPI transamidase component) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:7bBqUoVPfAOj/Pm4RPbzshzWNr0559292 rogid:amv3rxKpKmjGpnjzMInYFQXvlUg559292 intact-crc:BC116C7CC785FD33|rigid:fPlvN4AO3uuMITE1bx1812uNDtA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39016 uniprotkb:P24276 intact:EBI-2052996|uniprotkb:D6VTX5|ensemblfungi:YGL178W intact:EBI-18153|uniprotkb:D6VSS2|ensemblfungi:YDR293C psi-mi:mpt5_yeast(display_long)|uniprotkb:HTR1(gene name synonym)|uniprotkb:PUF5(gene name synonym)|uniprotkb:Protein HTR1(gene name synonym)|uniprotkb:BIC834(orf name)|uniprotkb:YGL178W(locus name)|uniprotkb:MPT5(gene name)|psi-mi:MPT5(display_short)|uniprotkb:Pumilio homology domain family member 5(gene name synonym) psi-mi:ssd1_yeast(display_long)|uniprotkb:SSD1(gene name)|psi-mi:SSD1(display_short)|uniprotkb:CLA1(gene name synonym)|uniprotkb:RLD1(gene name synonym)|uniprotkb:SRK1(gene name synonym)|uniprotkb:YDR293C(locus name)|uniprotkb:D9819.4(orf name)|uniprotkb:Protein SRK1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330436|imex:IM-14275-1501 author score:97.40 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011337.1|sgd:S000003146|dip:DIP-2271N|mint:P39016|ensemblfungi:YGL178W(gene)|ensemblfungi:YGL178W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:5BYM|rcsb pdb:5BZ1|rcsb pdb:5BZ5|rcsb pdb:5BZU|rcsb pdb:5BZV refseq:NP_010579.1|sgd:S000002701|ensemblfungi:YDR293C(gene)|ensemblfungi:YDR293C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051301"(cell division)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR041093|interpro:IPR041505|rcsb pdb:5NCL|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007049"(cell cycle)|dip:DIP-6449N|mint:P24276 psi-mi:"MI:0469"(intact) crc64:6B289BAF3CEA2200 crc64:3D50FD6838ECA514 figure legend:tables S3 and S4|author-confidence:97.40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tWA8mxLeerefKvNZOERVljO8uHQ559292 rogid:myt8+lnu2/li6TuGiM5GBfMtUiw559292 intact-crc:4A2A7E82B1714C1A|rigid:hXVBsCzQXI4Kfn2AYfA20A8IqK8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39016 uniprotkb:P25567 intact:EBI-2052996|uniprotkb:D6VTX5|ensemblfungi:YGL178W intact:EBI-18084|uniprotkb:D6VQX8|ensemblfungi:YCL037C psi-mi:mpt5_yeast(display_long)|uniprotkb:HTR1(gene name synonym)|uniprotkb:PUF5(gene name synonym)|uniprotkb:Protein HTR1(gene name synonym)|uniprotkb:BIC834(orf name)|uniprotkb:YGL178W(locus name)|uniprotkb:MPT5(gene name)|psi-mi:MPT5(display_short)|uniprotkb:Pumilio homology domain family member 5(gene name synonym) psi-mi:sro9_yeast(display_long)|uniprotkb:SRO9(gene name)|psi-mi:SRO9(display_short)|uniprotkb:YCL037C(locus name)|uniprotkb:YCL37C(orf name)|uniprotkb:Suppressor of RHO3 protein 9(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330447|imex:IM-14275-1502 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011337.1|sgd:S000003146|dip:DIP-2271N|mint:P39016|ensemblfungi:YGL178W(gene)|ensemblfungi:YGL178W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:5BYM|rcsb pdb:5BZ1|rcsb pdb:5BZ5|rcsb pdb:5BZU|rcsb pdb:5BZV refseq:NP_009893.2|sgd:S000000542|ensemblfungi:YCL037C(gene)|ensemblfungi:YCL037C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|dip:DIP-6638N|mint:P25567 psi-mi:"MI:0469"(intact) crc64:6B289BAF3CEA2200 crc64:B1B720D40C7B9914 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tWA8mxLeerefKvNZOERVljO8uHQ559292 rogid:CouwiBsK7S3Tm6CoBsu3LdWfelg559292 intact-crc:D139B027008A9B11|rigid:xdtjjKJaA9c8gUt8g9td0pJrDSQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25655 uniprotkb:P39016 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-2052996|uniprotkb:D6VTX5|ensemblfungi:YGL178W psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:mpt5_yeast(display_long)|uniprotkb:HTR1(gene name synonym)|uniprotkb:PUF5(gene name synonym)|uniprotkb:Protein HTR1(gene name synonym)|uniprotkb:BIC834(orf name)|uniprotkb:YGL178W(locus name)|uniprotkb:MPT5(gene name)|psi-mi:MPT5(display_short)|uniprotkb:Pumilio homology domain family member 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330458|imex:IM-14275-1503 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 refseq:NP_011337.1|sgd:S000003146|dip:DIP-2271N|mint:P39016|ensemblfungi:YGL178W(gene)|ensemblfungi:YGL178W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:5BYM|rcsb pdb:5BZ1|rcsb pdb:5BZ5|rcsb pdb:5BZU|rcsb pdb:5BZV psi-mi:"MI:0469"(intact) crc64:5B2AE15BCF95E009 crc64:6B289BAF3CEA2200 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:tWA8mxLeerefKvNZOERVljO8uHQ559292 intact-crc:81AB132E77B3E6B7|rigid:LWH7tdA6eaM35D8ez/0dgZv7Tgc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32588 uniprotkb:P39016 intact:EBI-14231|ensemblfungi:YNL016W|uniprotkb:D6W1G2 intact:EBI-2052996|uniprotkb:D6VTX5|ensemblfungi:YGL178W psi-mi:pub1_yeast(display_long)|uniprotkb:ARS consensus-binding protein ACBP-60(gene name synonym)|uniprotkb:Poly uridylate-binding protein(gene name synonym)|uniprotkb:PUB1(gene name)|psi-mi:PUB1(display_short)|uniprotkb:RNP1(gene name synonym)|uniprotkb:YNL016W(locus name)|uniprotkb:N2842(orf name) psi-mi:mpt5_yeast(display_long)|uniprotkb:HTR1(gene name synonym)|uniprotkb:PUF5(gene name synonym)|uniprotkb:Protein HTR1(gene name synonym)|uniprotkb:BIC834(orf name)|uniprotkb:YGL178W(locus name)|uniprotkb:MPT5(gene name)|psi-mi:MPT5(display_short)|uniprotkb:Pumilio homology domain family member 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330469|imex:IM-14275-1504 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014382.1|sgd:S000004961|ensemblfungi:YNL016W(gene)|ensemblfungi:YNL016W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043488"(regulation of mRNA stability)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034509|interpro:IPR034639|interpro:IPR035979|rcsb pdb:2LA4|rcsb pdb:3MD1|rcsb pdb:3MD3|rcsb pdb:6Z29|mint:P32588|dip:DIP-5480N refseq:NP_011337.1|sgd:S000003146|dip:DIP-2271N|mint:P39016|ensemblfungi:YGL178W(gene)|ensemblfungi:YGL178W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:5BYM|rcsb pdb:5BZ1|rcsb pdb:5BZ5|rcsb pdb:5BZU|rcsb pdb:5BZV psi-mi:"MI:0469"(intact) crc64:3B81A7735505D3CA crc64:6B289BAF3CEA2200 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8xFMuEva7leVYDKg3WOmvPtRTFk559292 rogid:tWA8mxLeerefKvNZOERVljO8uHQ559292 intact-crc:B832C2D5864E566A|rigid:HyUJXYxVk5JwhdVNrIZJVa7OE/Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39016 uniprotkb:P35732 intact:EBI-2052996|uniprotkb:D6VTX5|ensemblfungi:YGL178W intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C psi-mi:mpt5_yeast(display_long)|uniprotkb:HTR1(gene name synonym)|uniprotkb:PUF5(gene name synonym)|uniprotkb:Protein HTR1(gene name synonym)|uniprotkb:BIC834(orf name)|uniprotkb:YGL178W(locus name)|uniprotkb:MPT5(gene name)|psi-mi:MPT5(display_short)|uniprotkb:Pumilio homology domain family member 5(gene name synonym) psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330480|imex:IM-14275-1505 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011337.1|sgd:S000003146|dip:DIP-2271N|mint:P39016|ensemblfungi:YGL178W(gene)|ensemblfungi:YGL178W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:5BYM|rcsb pdb:5BZ1|rcsb pdb:5BZ5|rcsb pdb:5BZU|rcsb pdb:5BZV refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 psi-mi:"MI:0469"(intact) crc64:6B289BAF3CEA2200 crc64:05734E2D0B7389AC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tWA8mxLeerefKvNZOERVljO8uHQ559292 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 intact-crc:64BF8CDE3F548755|rigid:E8QwaK9msFCLxP2vwIY2IJb4FzM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39008 uniprotkb:P39016 intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C intact:EBI-2052996|uniprotkb:D6VTX5|ensemblfungi:YGL178W psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:mpt5_yeast(display_long)|uniprotkb:HTR1(gene name synonym)|uniprotkb:PUF5(gene name synonym)|uniprotkb:Protein HTR1(gene name synonym)|uniprotkb:BIC834(orf name)|uniprotkb:YGL178W(locus name)|uniprotkb:MPT5(gene name)|psi-mi:MPT5(display_short)|uniprotkb:Pumilio homology domain family member 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330491|imex:IM-14275-1506 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N refseq:NP_011337.1|sgd:S000003146|dip:DIP-2271N|mint:P39016|ensemblfungi:YGL178W(gene)|ensemblfungi:YGL178W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:5BYM|rcsb pdb:5BZ1|rcsb pdb:5BZ5|rcsb pdb:5BZU|rcsb pdb:5BZV psi-mi:"MI:0469"(intact) crc64:F3CAF97106A65933 crc64:6B289BAF3CEA2200 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 rogid:tWA8mxLeerefKvNZOERVljO8uHQ559292 intact-crc:5F9C6D7EA3B3FA1B|rigid:2fksR3lAc8Qy5ru10DkPE8Fo+/E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39517 uniprotkb:P39016 intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C intact:EBI-2052996|uniprotkb:D6VTX5|ensemblfungi:YGL178W psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:mpt5_yeast(display_long)|uniprotkb:HTR1(gene name synonym)|uniprotkb:PUF5(gene name synonym)|uniprotkb:Protein HTR1(gene name synonym)|uniprotkb:BIC834(orf name)|uniprotkb:YGL178W(locus name)|uniprotkb:MPT5(gene name)|psi-mi:MPT5(display_short)|uniprotkb:Pumilio homology domain family member 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330502|imex:IM-14275-1507 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 refseq:NP_011337.1|sgd:S000003146|dip:DIP-2271N|mint:P39016|ensemblfungi:YGL178W(gene)|ensemblfungi:YGL178W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:5BYM|rcsb pdb:5BZ1|rcsb pdb:5BZ5|rcsb pdb:5BZU|rcsb pdb:5BZV psi-mi:"MI:0469"(intact) crc64:062CFA56DF6F2CEE crc64:6B289BAF3CEA2200 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 rogid:tWA8mxLeerefKvNZOERVljO8uHQ559292 intact-crc:1291BD03DFF0C8E0|rigid:RShFm7bxaDsShmeEMQMYrB5SATw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40016 uniprotkb:P39016 intact:EBI-15927|uniprotkb:D3DLS0|ensemblfungi:YER021W intact:EBI-2052996|uniprotkb:D6VTX5|ensemblfungi:YGL178W psi-mi:rpn3_yeast(display_long)|uniprotkb:RPN3(gene name)|psi-mi:RPN3(display_short)|uniprotkb:SUN2(gene name synonym)|uniprotkb:YER021W(locus name) psi-mi:mpt5_yeast(display_long)|uniprotkb:HTR1(gene name synonym)|uniprotkb:PUF5(gene name synonym)|uniprotkb:Protein HTR1(gene name synonym)|uniprotkb:BIC834(orf name)|uniprotkb:YGL178W(locus name)|uniprotkb:MPT5(gene name)|psi-mi:MPT5(display_short)|uniprotkb:Pumilio homology domain family member 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330513|imex:IM-14275-1508 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010938.1|sgd:S000000823|ensemblfungi:YER021W(gene)|ensemblfungi:YER021W_mRNA(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042176"(regulation of protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|dip:DIP-1322N|mint:P40016 refseq:NP_011337.1|sgd:S000003146|dip:DIP-2271N|mint:P39016|ensemblfungi:YGL178W(gene)|ensemblfungi:YGL178W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:5BYM|rcsb pdb:5BZ1|rcsb pdb:5BZ5|rcsb pdb:5BZU|rcsb pdb:5BZV psi-mi:"MI:0469"(intact) crc64:B08B58663DDA85DC crc64:6B289BAF3CEA2200 figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pXkyoZKr0rI5usi19R+TvS4hSso559292 rogid:tWA8mxLeerefKvNZOERVljO8uHQ559292 intact-crc:58F5A71C3AE70269|rigid:PL/KQbu0ITKyO/X+HnOrIyy68tQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40070 uniprotkb:P39016 intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W intact:EBI-2052996|uniprotkb:D6VTX5|ensemblfungi:YGL178W psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:mpt5_yeast(display_long)|uniprotkb:HTR1(gene name synonym)|uniprotkb:PUF5(gene name synonym)|uniprotkb:Protein HTR1(gene name synonym)|uniprotkb:BIC834(orf name)|uniprotkb:YGL178W(locus name)|uniprotkb:MPT5(gene name)|psi-mi:MPT5(display_short)|uniprotkb:Pumilio homology domain family member 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330524|imex:IM-14275-1509 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 refseq:NP_011337.1|sgd:S000003146|dip:DIP-2271N|mint:P39016|ensemblfungi:YGL178W(gene)|ensemblfungi:YGL178W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:5BYM|rcsb pdb:5BZ1|rcsb pdb:5BZ5|rcsb pdb:5BZU|rcsb pdb:5BZV psi-mi:"MI:0469"(intact) crc64:69CAC1F01D5BFA98 crc64:6B289BAF3CEA2200 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 rogid:tWA8mxLeerefKvNZOERVljO8uHQ559292 intact-crc:EEA0DC823A22FE56|rigid:5dRWpIyZ+ixPldmJr28zM+czC48 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53829 uniprotkb:P39016 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-2052996|uniprotkb:D6VTX5|ensemblfungi:YGL178W psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:mpt5_yeast(display_long)|uniprotkb:HTR1(gene name synonym)|uniprotkb:PUF5(gene name synonym)|uniprotkb:Protein HTR1(gene name synonym)|uniprotkb:BIC834(orf name)|uniprotkb:YGL178W(locus name)|uniprotkb:MPT5(gene name)|psi-mi:MPT5(display_short)|uniprotkb:Pumilio homology domain family member 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330535|imex:IM-14275-1510 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 refseq:NP_011337.1|sgd:S000003146|dip:DIP-2271N|mint:P39016|ensemblfungi:YGL178W(gene)|ensemblfungi:YGL178W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:5BYM|rcsb pdb:5BZ1|rcsb pdb:5BZ5|rcsb pdb:5BZU|rcsb pdb:5BZV psi-mi:"MI:0469"(intact) crc64:F3DBABE6AD3C7F3C crc64:6B289BAF3CEA2200 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:tWA8mxLeerefKvNZOERVljO8uHQ559292 intact-crc:235462CB43533968|rigid:RhLXkfRLu/l3L6DfoVRZ9QTTObY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39079 uniprotkb:P46675 intact:EBI-19077|uniprotkb:D6VSH1|ensemblfungi:YDR188W intact:EBI-18471|uniprotkb:D6VY47|ensemblfungi:YLR045C psi-mi:tcpz_yeast(display_long)|uniprotkb:CCT6(gene name)|psi-mi:CCT6(display_short)|uniprotkb:TCP20(gene name synonym)|uniprotkb:TCP6(gene name synonym)|uniprotkb:YDR188W(locus name)|uniprotkb:YD9395.21(orf name)|uniprotkb:CCT-zeta(gene name synonym) psi-mi:stu2_yeast(display_long)|uniprotkb:STU2(gene name)|psi-mi:STU2(display_short)|uniprotkb:YLR045C(locus name)|uniprotkb:L2108(orf name)|uniprotkb:Suppressor of tubulin 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330546|imex:IM-14275-1511 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002596|ensemblfungi:YDR188W(gene)|ensemblfungi:YDR188W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|rcsb pdb:6KRD|refseq:NP_010474.3|dip:DIP-6401N|mint:P39079 go:"GO:0005938"(cell cortex)|refseq:NP_013146.1|sgd:S000004035|ensemblfungi:YLR045C(gene)|ensemblfungi:YLR045C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005816"(spindle pole body)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0061863"(microtubule plus end polymerase)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR034085|rcsb pdb:2QK1|rcsb pdb:4FFB|rcsb pdb:4U3J|rcsb pdb:6BL7|rcsb pdb:7KDF|dip:DIP-2462N|mint:P46675 psi-mi:"MI:0469"(intact) crc64:7D2A2AB4526D3DB4 crc64:7A49C3702E21C7BF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:D9HUMBTSH1Tsm/XHNMIOdd6YxEw559292 rogid:MZSvgMGh+d1BYxGm4AEptyNQRfk559292 intact-crc:91DFDD51E6C6CF3B|rigid:3zZf/foYLXPMvO8Zeodby9rpRdk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40016 uniprotkb:P39083 intact:EBI-15927|uniprotkb:D3DLS0|ensemblfungi:YER021W intact:EBI-15044|uniprotkb:P39934|uniprotkb:D6W2I5|ensemblfungi:YOR127W psi-mi:rpn3_yeast(display_long)|uniprotkb:RPN3(gene name)|psi-mi:RPN3(display_short)|uniprotkb:SUN2(gene name synonym)|uniprotkb:YER021W(locus name) psi-mi:rga1_yeast(display_long)|uniprotkb:RGA1(gene name)|psi-mi:RGA1(display_short)|uniprotkb:DBM1(gene name synonym)|uniprotkb:THE1(gene name synonym)|uniprotkb:YOR127W(locus name)|uniprotkb:O3290(orf name)|uniprotkb:YOR3290W(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330557|imex:IM-14275-1512 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010938.1|sgd:S000000823|ensemblfungi:YER021W(gene)|ensemblfungi:YER021W_mRNA(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042176"(regulation of protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|dip:DIP-1322N|mint:P40016 refseq:NP_014770.1|sgd:S000005653|ensemblfungi:YOR127W(gene)|ensemblfungi:YOR127W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005621"(cellular bud scar)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007015"(actin filament organization)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007119"(budding cell isotropic bud growth)|go:"GO:0007120"(axial cellular bud site selection)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0071597"(cellular birth scar)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|dip:DIP-1559N|mint:P39083 psi-mi:"MI:0469"(intact) crc64:B08B58663DDA85DC crc64:C805411B57553791 figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pXkyoZKr0rI5usi19R+TvS4hSso559292 rogid:xdYXgZQ0mCidt7tTuMXDCcBQIxc559292 intact-crc:299902AA5B0E4E79|rigid:pa0YdouqRQb4zQ1FN+gwH7j7MuM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39111 uniprotkb:P31412 intact:EBI-20272|uniprotkb:D6VUF5|ensemblfungi:YGR020C intact:EBI-20260|uniprotkb:D6VXK7|ensemblfungi:YKL080W psi-mi:vatf_yeast(display_long)|uniprotkb:VMA7(gene name)|psi-mi:VMA7(display_short)|uniprotkb:YGR020C(locus name)|uniprotkb:Vacuolar proton pump subunit F(gene name synonym)|uniprotkb:V-ATPase 14 kDa subunit(gene name synonym) psi-mi:vatc_yeast(display_long)|uniprotkb:VMA5(gene name)|psi-mi:VMA5(display_short)|uniprotkb:VAT3(gene name synonym)|uniprotkb:VATC(gene name synonym)|uniprotkb:YKL410(orf name)|uniprotkb:YKL080W(locus name)|uniprotkb:Vacuolar proton pump subunit C(gene name synonym)|uniprotkb:V-ATPase 42 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330568|imex:IM-14275-1513 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011534.1|sgd:S000003252|ensemblfungi:YGR020C(gene)|ensemblfungi:YGR020C_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016020"(membrane)|go:"GO:0042625"(ATPase-coupled ion transmembrane transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005772(ATPase, V1 complex, subunit F, eukaryotic)|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|interpro:IPR036906|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4IX9|rcsb pdb:4RND|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2077N|mint:P39111 refseq:NP_012843.1|sgd:S000001563|ensemblfungi:YKL080W(gene)|ensemblfungi:YKL080W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004907(ATPase, V1 complex, subunit C)|interpro:IPR036132|rcsb pdb:1U7L|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4DL0|rcsb pdb:4EFA|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-4701N|mint:P31412 psi-mi:"MI:0469"(intact) crc64:D21EC0980EB99DFF crc64:0CD1B814046C377E figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VtthQl2jj9fpjv3psX0YUNbIAKU559292 rogid:NBI0upCB5yxAyMQgccBcLhjZk8s559292 intact-crc:1FC47F71C4C81F40|rigid:f7Ise6aaNvFmCz4ifop1qI4Qrww false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32366 uniprotkb:P39111 intact:EBI-20201|uniprotkb:D6VZ81|ensemblfungi:YLR447C intact:EBI-20272|uniprotkb:D6VUF5|ensemblfungi:YGR020C psi-mi:va0d_yeast(display_long)|uniprotkb:VMA6(gene name)|psi-mi:VMA6(display_short)|uniprotkb:YLR447C(locus name)|uniprotkb:L9324.8(orf name)|uniprotkb:Vacuolar proton pump subunit d(gene name synonym)|uniprotkb:V-ATPase 39 kDa subunit(gene name synonym)|uniprotkb:V-ATPase subunit M39(gene name synonym) psi-mi:vatf_yeast(display_long)|uniprotkb:VMA7(gene name)|psi-mi:VMA7(display_short)|uniprotkb:YGR020C(locus name)|uniprotkb:Vacuolar proton pump subunit F(gene name synonym)|uniprotkb:V-ATPase 14 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330579|imex:IM-14275-1514 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004439|refseq:NP_013552.3|mint:P32366|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR036079|interpro:IPR044911|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|ensemblfungi:YLR447C(gene)|ensemblfungi:YLR447C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|rcsb pdb:6PE4|dip:DIP-1737N refseq:NP_011534.1|sgd:S000003252|ensemblfungi:YGR020C(gene)|ensemblfungi:YGR020C_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016020"(membrane)|go:"GO:0042625"(ATPase-coupled ion transmembrane transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005772(ATPase, V1 complex, subunit F, eukaryotic)|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|interpro:IPR036906|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4IX9|rcsb pdb:4RND|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2077N|mint:P39111 psi-mi:"MI:0469"(intact) crc64:53A19450CAF35632 crc64:D21EC0980EB99DFF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ux3Cd8Fl9t/GGgcKAzJevZQFWnE559292 rogid:VtthQl2jj9fpjv3psX0YUNbIAKU559292 intact-crc:C961EAA02E032D2A|rigid:czuWEFSwHYB3b6vwZ1M9Qxzbbt4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39111 uniprotkb:P32563 intact:EBI-20272|uniprotkb:D6VUF5|ensemblfungi:YGR020C intact:EBI-20455|uniprotkb:D6W2X0|ensemblfungi:YOR270C psi-mi:vatf_yeast(display_long)|uniprotkb:VMA7(gene name)|psi-mi:VMA7(display_short)|uniprotkb:YGR020C(locus name)|uniprotkb:Vacuolar proton pump subunit F(gene name synonym)|uniprotkb:V-ATPase 14 kDa subunit(gene name synonym) psi-mi:vph1_yeast(display_long)|uniprotkb:VPH1(gene name)|psi-mi:VPH1(display_short)|uniprotkb:Vacuolar proton pump a subunit(gene name synonym)|uniprotkb:V-ATPase 95 kDa subunit(gene name synonym)|uniprotkb:Vacuolar pH protein 1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase subunit a 1(gene name synonym)|uniprotkb:YOR270C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330590|imex:IM-14275-1515 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011534.1|sgd:S000003252|ensemblfungi:YGR020C(gene)|ensemblfungi:YGR020C_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016020"(membrane)|go:"GO:0042625"(ATPase-coupled ion transmembrane transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005772(ATPase, V1 complex, subunit F, eukaryotic)|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|interpro:IPR036906|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4IX9|rcsb pdb:4RND|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2077N|mint:P39111 sgd:S000005796|refseq:NP_014913.3|ensemblfungi:YOR270C(gene)|ensemblfungi:YOR270C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0034622"|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:0071469"(cellular response to alkaline pH)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|rcsb pdb:2JTW|rcsb pdb:2NVJ|rcsb pdb:2RPW|rcsb pdb:3J9T|go:"GO:0007035"(vacuolar acidification)|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5I1M|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6HH0|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2960N|mint:P32563 psi-mi:"MI:0469"(intact) crc64:D21EC0980EB99DFF crc64:77709A914410CD4D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VtthQl2jj9fpjv3psX0YUNbIAKU559292 rogid:c+aKW/ZUnBlGW7ZqOLD/0mpICdQ559292 intact-crc:BA02ACB666875B75|rigid:ZceeigccP5OYA2j4C+ZrtVj8sq8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39111 uniprotkb:P32610 intact:EBI-20272|uniprotkb:D6VUF5|ensemblfungi:YGR020C intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W psi-mi:vatf_yeast(display_long)|uniprotkb:VMA7(gene name)|psi-mi:VMA7(display_short)|uniprotkb:YGR020C(locus name)|uniprotkb:Vacuolar proton pump subunit F(gene name synonym)|uniprotkb:V-ATPase 14 kDa subunit(gene name synonym) psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330601|imex:IM-14275-1516 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011534.1|sgd:S000003252|ensemblfungi:YGR020C(gene)|ensemblfungi:YGR020C_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016020"(membrane)|go:"GO:0042625"(ATPase-coupled ion transmembrane transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005772(ATPase, V1 complex, subunit F, eukaryotic)|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|interpro:IPR036906|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4IX9|rcsb pdb:4RND|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2077N|mint:P39111 refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610 psi-mi:"MI:0469"(intact) crc64:D21EC0980EB99DFF crc64:FDE93E1FAF0AEC5B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VtthQl2jj9fpjv3psX0YUNbIAKU559292 rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292 intact-crc:E6140FBBBE3258F0|rigid:Z+rHmQZwJN6Y6r8oAOkfWKs4+hs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39111 uniprotkb:P39968 intact:EBI-20272|uniprotkb:D6VUF5|ensemblfungi:YGR020C intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W psi-mi:vatf_yeast(display_long)|uniprotkb:VMA7(gene name)|psi-mi:VMA7(display_short)|uniprotkb:YGR020C(locus name)|uniprotkb:Vacuolar proton pump subunit F(gene name synonym)|uniprotkb:V-ATPase 14 kDa subunit(gene name synonym) psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330612|imex:IM-14275-1517 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011534.1|sgd:S000003252|ensemblfungi:YGR020C(gene)|ensemblfungi:YGR020C_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016020"(membrane)|go:"GO:0042625"(ATPase-coupled ion transmembrane transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005772(ATPase, V1 complex, subunit F, eukaryotic)|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|interpro:IPR036906|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4IX9|rcsb pdb:4RND|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2077N|mint:P39111 sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N psi-mi:"MI:0469"(intact) crc64:D21EC0980EB99DFF crc64:B2E75774B47E5933 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VtthQl2jj9fpjv3psX0YUNbIAKU559292 rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292 intact-crc:B9C59BA2BCA7A0B6|rigid:XM2tLGSgZJ8GiITyZmXh0pBkgk0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39111 uniprotkb:P41807 intact:EBI-20272|uniprotkb:D6VUF5|ensemblfungi:YGR020C intact:EBI-20281|uniprotkb:D6W446|ensemblfungi:YPR036W psi-mi:vatf_yeast(display_long)|uniprotkb:VMA7(gene name)|psi-mi:VMA7(display_short)|uniprotkb:YGR020C(locus name)|uniprotkb:Vacuolar proton pump subunit F(gene name synonym)|uniprotkb:V-ATPase 14 kDa subunit(gene name synonym) psi-mi:vath_yeast(display_long)|uniprotkb:YP3085.02(orf name)|uniprotkb:VMA13(gene name)|psi-mi:VMA13(display_short)|uniprotkb:CLS11(gene name synonym)|uniprotkb:YPR036W(locus name)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 54 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330623|imex:IM-14275-1518 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011534.1|sgd:S000003252|ensemblfungi:YGR020C(gene)|ensemblfungi:YGR020C_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016020"(membrane)|go:"GO:0042625"(ATPase-coupled ion transmembrane transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005772(ATPase, V1 complex, subunit F, eukaryotic)|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|interpro:IPR036906|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4IX9|rcsb pdb:4RND|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2077N|mint:P39111 refseq:NP_015361.1|sgd:S000006240|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|rcsb pdb:1HO8|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YPR036W(gene)|ensemblfungi:YPR036W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|dip:DIP-6640N|mint:P41807 psi-mi:"MI:0469"(intact) crc64:D21EC0980EB99DFF crc64:54131FF9C2C87594 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VtthQl2jj9fpjv3psX0YUNbIAKU559292 rogid:kEXWvOsnTk0WdgGOny+mufz4lTo559292 intact-crc:7ACB0FC9E344D553|rigid:db4/7FDFjAyUfYQ2OVU5n5gtw1s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39111 uniprotkb:P53262 intact:EBI-20272|uniprotkb:D6VUF5|ensemblfungi:YGR020C intact:EBI-2061527|uniprotkb:D6VUN8|ensemblfungi:YGR106C psi-mi:vatf_yeast(display_long)|uniprotkb:VMA7(gene name)|psi-mi:VMA7(display_short)|uniprotkb:YGR020C(locus name)|uniprotkb:Vacuolar proton pump subunit F(gene name synonym)|uniprotkb:V-ATPase 14 kDa subunit(gene name synonym) psi-mi:voa1_yeast(display_long)|uniprotkb:YGR106C(locus name)|uniprotkb:VOA1(gene name)|psi-mi:VOA1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330634|imex:IM-14275-1519 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011534.1|sgd:S000003252|ensemblfungi:YGR020C(gene)|ensemblfungi:YGR020C_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016020"(membrane)|go:"GO:0042625"(ATPase-coupled ion transmembrane transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005772(ATPase, V1 complex, subunit F, eukaryotic)|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|interpro:IPR036906|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4IX9|rcsb pdb:4RND|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2077N|mint:P39111 sgd:S000003338|refseq:NP_011620.1|mint:P53262|ensemblfungi:YGR106C(gene)|ensemblfungi:YGR106C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034622"|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|rcsb pdb:6PE4|rcsb pdb:6PE5 psi-mi:"MI:0469"(intact) crc64:D21EC0980EB99DFF - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VtthQl2jj9fpjv3psX0YUNbIAKU559292 rogid:lKLIonttSEX36IQaIKlzxS/Cdxg559292 intact-crc:06EEE119E76FE8B6|rigid:aJcWL2flT75C1X4jjSPag/5a1zc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39111 uniprotkb:Q02205 intact:EBI-20272|uniprotkb:D6VUF5|ensemblfungi:YGR020C intact:EBI-27062|uniprotkb:D6VX73|ensemblfungi:YKR007W psi-mi:vatf_yeast(display_long)|uniprotkb:VMA7(gene name)|psi-mi:VMA7(display_short)|uniprotkb:YGR020C(locus name)|uniprotkb:Vacuolar proton pump subunit F(gene name synonym)|uniprotkb:V-ATPase 14 kDa subunit(gene name synonym) psi-mi:meh1_yeast(display_long)|uniprotkb:GSE complex subunit 2(gene name synonym)|uniprotkb:EGO complex subunit 1(gene name synonym)|uniprotkb:YKR007W(locus name)|uniprotkb:YK106(orf name)|uniprotkb:MEH1(gene name)|psi-mi:MEH1(display_short)|uniprotkb:EGO1(gene name synonym)|uniprotkb:GSE2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330645|imex:IM-14275-1520 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011534.1|sgd:S000003252|ensemblfungi:YGR020C(gene)|ensemblfungi:YGR020C_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016020"(membrane)|go:"GO:0042625"(ATPase-coupled ion transmembrane transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005772(ATPase, V1 complex, subunit F, eukaryotic)|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|interpro:IPR036906|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4IX9|rcsb pdb:4RND|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2077N|mint:P39111 sgd:S000001715|refseq:NP_012932.1|mint:Q02205|dip:DIP-1922N|ensemblfungi:YKR007W(gene)|ensemblfungi:YKR007W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0005829"(cytosol)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007040"(lysosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR028209|rcsb pdb:4XPM|rcsb pdb:6JWP psi-mi:"MI:0469"(intact) crc64:D21EC0980EB99DFF crc64:995DD1E68331D050 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VtthQl2jj9fpjv3psX0YUNbIAKU559292 rogid:73a6e5W5wQixGg2aGXDo4A6NR2s559292 intact-crc:757FBA250377F24D|rigid:ffteWkKEoE/oOBKrwuh/yr/xdpg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06634 uniprotkb:P39517 intact:EBI-5744|uniprotkb:D6W2R0|ensemblfungi:YOR204W intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C psi-mi:ded1_yeast(display_long)|uniprotkb:DED1(gene name)|psi-mi:DED1(display_short)|uniprotkb:SPP81(gene name synonym)|uniprotkb:YOR204W(locus name)|uniprotkb:DEAD box protein 1(gene name synonym) psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330656|imex:IM-14275-1521 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005730|refseq:NP_014847.3|dip:DIP-5820N|mint:P06634|ensemblfungi:YOR204W(gene)|ensemblfungi:YOR204W_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763|reactome:R-SCE-6798695 sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:B6722D94C03BFA4B crc64:062CFA56DF6F2CEE figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FkldumX6m5gBuuaG09aTJ0kuMZM559292 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 intact-crc:673F891C192F8A1B|rigid:llNQ3DANlRxh/R/U6pse6peg8Y8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25339 uniprotkb:P39517 intact:EBI-23703|uniprotkb:D6VUC3|ensemblfungi:YGL014W intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C psi-mi:puf4_yeast(display_long)|uniprotkb:PUF4(gene name)|psi-mi:PUF4(display_short)|uniprotkb:YGL023(orf name)|uniprotkb:YGL014W(locus name) psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330667|imex:IM-14275-1522 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011501.1|sgd:S000002982|dip:DIP-2638N|mint:P25339|ensemblfungi:YGL014W(gene)|ensemblfungi:YGL014W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:3BWT|rcsb pdb:3BX2|rcsb pdb:3BX3|rcsb pdb:4DZS|go:"GO:0003729"(mRNA binding) sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:659BA1062439F642 crc64:062CFA56DF6F2CEE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:spjnSzTKOyi8X0oMi4wOTS+72hY559292 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 intact-crc:6612DC62704AF410|rigid:TJvTlndawhSzIhbnA2EZ4bimXLg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25567 uniprotkb:P39517 intact:EBI-18084|uniprotkb:D6VQX8|ensemblfungi:YCL037C intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C psi-mi:sro9_yeast(display_long)|uniprotkb:SRO9(gene name)|psi-mi:SRO9(display_short)|uniprotkb:YCL037C(locus name)|uniprotkb:YCL37C(orf name)|uniprotkb:Suppressor of RHO3 protein 9(gene name synonym) psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330678|imex:IM-14275-1523 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009893.2|sgd:S000000542|ensemblfungi:YCL037C(gene)|ensemblfungi:YCL037C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|dip:DIP-6638N|mint:P25567 sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:B1B720D40C7B9914 crc64:062CFA56DF6F2CEE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CouwiBsK7S3Tm6CoBsu3LdWfelg559292 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 intact-crc:7C949A5C02C07760|rigid:nR2UDHWz65GPIbVSik23mNLeW78 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25644 uniprotkb:P39517 intact:EBI-204|uniprotkb:Q8NKJ3|uniprotkb:D6VR80|ensemblfungi:YCR077C intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C psi-mi:pat1_yeast(display_long)|uniprotkb:PAT1(gene name)|psi-mi:PAT1(display_short)|uniprotkb:Decapping activator and translational repressor PAT1(gene name synonym)|uniprotkb:mRNA turnover protein 1(gene name synonym)|uniprotkb:MRT1(gene name synonym)|uniprotkb:Topoisomerase II-associated protein PAT1(gene name synonym)|uniprotkb:YCR77C(orf name)|uniprotkb:YCR077C(locus name) psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330689|imex:IM-14275-1524 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010002.3|sgd:S000000673|mint:P25644|dip:DIP-883N|ensemblfungi:YCR077C(gene)|ensemblfungi:YCR077C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000776"(kinetochore)|go:"GO:0000932"(P-body)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033962"(P-body assembly)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0051301"(cell division)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR019167|interpro:IPR039900|rcsb pdb:4BRW|rcsb pdb:4C8Q|rcsb pdb:4N0A|rcsb pdb:4OGP|rcsb pdb:4OJJ|rcsb pdb:5LM5|rcsb pdb:5LMF|rcsb pdb:5LMG|reactome:R-SCE-430039 sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:2DBE1210C173E468 crc64:062CFA56DF6F2CEE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kov8R0RAgIOPffQ7ydjCUxjoE/M559292 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 intact-crc:42673951CC3DEB1C|rigid:cdAkbB9vnOm/eID5jNKGA5ijV8k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39517 uniprotkb:P25655 intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330700|imex:IM-14275-1525 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 psi-mi:"MI:0469"(intact) crc64:062CFA56DF6F2CEE crc64:5B2AE15BCF95E009 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 intact-crc:2C06395575F90AC6|rigid:90363/5wDPyQSWfOAklM/FQn86I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30771 uniprotkb:P39517 intact:EBI-11831|ensemblfungi:YMR080C|uniprotkb:D6VZQ4 intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C psi-mi:nam7_yeast(display_long)|uniprotkb:NAM7(gene name)|psi-mi:NAM7(display_short)|uniprotkb:IFS2(gene name synonym)|uniprotkb:MOF4(gene name synonym)|uniprotkb:Nonsense-mediated mRNA decay protein 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1(gene name synonym)|uniprotkb:UPF1(gene name synonym)|uniprotkb:YM9582.05C(orf name)|uniprotkb:YMR080C(locus name)|uniprotkb:Nuclear accommodation of mitochondria 7 protein(gene name synonym) psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330711|imex:IM-14275-1526 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR080C(gene)|ensemblfungi:YMR080C_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006310"(DNA recombination)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|rcsb pdb:2XZL|reactome:R-SCE-975956|reactome:R-SCE-975957|go:"GO:0003729"(mRNA binding)|refseq:NP_013797.1|sgd:S000004685|dip:DIP-2373N|mint:P30771 sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:9161AFB0BE6747FE crc64:062CFA56DF6F2CEE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:f+dpOF+VBHbkicUTBu2HejagP2s559292 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 intact-crc:0D93F44DE86133CB|rigid:Veg9Hd7I4D2AgeUSAoXoFNv+jDw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32588 uniprotkb:P39517 intact:EBI-14231|ensemblfungi:YNL016W|uniprotkb:D6W1G2 intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C psi-mi:pub1_yeast(display_long)|uniprotkb:ARS consensus-binding protein ACBP-60(gene name synonym)|uniprotkb:Poly uridylate-binding protein(gene name synonym)|uniprotkb:PUB1(gene name)|psi-mi:PUB1(display_short)|uniprotkb:RNP1(gene name synonym)|uniprotkb:YNL016W(locus name)|uniprotkb:N2842(orf name) psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330722|imex:IM-14275-1527 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014382.1|sgd:S000004961|ensemblfungi:YNL016W(gene)|ensemblfungi:YNL016W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043488"(regulation of mRNA stability)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034509|interpro:IPR034639|interpro:IPR035979|rcsb pdb:2LA4|rcsb pdb:3MD1|rcsb pdb:3MD3|rcsb pdb:6Z29|mint:P32588|dip:DIP-5480N sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:3B81A7735505D3CA crc64:062CFA56DF6F2CEE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8xFMuEva7leVYDKg3WOmvPtRTFk559292 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 intact-crc:159FE8AE8404BA1B|rigid:EHHw3ii0oJykfLyicrxKG7YnfFM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34909 uniprotkb:P39517 intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330733|imex:IM-14275-1528 author score:93.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:8847084BD9BF48B7 crc64:062CFA56DF6F2CEE figure legend:tables S3 and S4|author-confidence:93.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 intact-crc:FF53124C1241EB3E|rigid:MQ6uqYWS97griFduu/vl1FKgpRQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39517 uniprotkb:P35732 intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330744|imex:IM-14275-1529 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 psi-mi:"MI:0469"(intact) crc64:062CFA56DF6F2CEE crc64:05734E2D0B7389AC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 intact-crc:C912A6A53D1E6B24|rigid:K616GIZs4HlO0ognZZvtd5YQ2sQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38828 uniprotkb:P39517 intact:EBI-24700|uniprotkb:D3DL71|ensemblfungi:YHR121W intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C psi-mi:lsm12_yeast(display_long)|uniprotkb:YHR121W(locus name)|uniprotkb:LSM12(gene name)|psi-mi:LSM12(display_short)|uniprotkb:Sm-like protein 12(gene name synonym) psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330755|imex:IM-14275-1530 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011989.1|sgd:S000001163|dip:DIP-5545N|mint:P38828|ensemblfungi:YHR121W(gene)|ensemblfungi:YHR121W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016070"(RNA metabolic process)|interpro:IPR016521(Uncharacterised conserved protein UCP007783, YHR121w)|interpro:IPR019181|interpro:IPR039683 sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) - crc64:062CFA56DF6F2CEE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6xw9WGjtFwkmKlO6QHoSSS2aMro559292 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 intact-crc:D676A064A8A60A2B|rigid:TcasaKkqzgXvLCs5+noqBTabdx0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39016 uniprotkb:P39517 intact:EBI-2052996|uniprotkb:D6VTX5|ensemblfungi:YGL178W intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C psi-mi:mpt5_yeast(display_long)|uniprotkb:HTR1(gene name synonym)|uniprotkb:PUF5(gene name synonym)|uniprotkb:Protein HTR1(gene name synonym)|uniprotkb:BIC834(orf name)|uniprotkb:YGL178W(locus name)|uniprotkb:MPT5(gene name)|psi-mi:MPT5(display_short)|uniprotkb:Pumilio homology domain family member 5(gene name synonym) psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330766|imex:IM-14275-1531 author score:87.93 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011337.1|sgd:S000003146|dip:DIP-2271N|mint:P39016|ensemblfungi:YGL178W(gene)|ensemblfungi:YGL178W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:5BYM|rcsb pdb:5BZ1|rcsb pdb:5BZ5|rcsb pdb:5BZU|rcsb pdb:5BZV sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:6B289BAF3CEA2200 crc64:062CFA56DF6F2CEE figure legend:tables S3 and S4|author-confidence:87.93|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tWA8mxLeerefKvNZOERVljO8uHQ559292 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 intact-crc:93529B0BC9BC4C6E|rigid:RShFm7bxaDsShmeEMQMYrB5SATw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39517 uniprotkb:P39517 intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330777|imex:IM-14275-1532 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:062CFA56DF6F2CEE crc64:062CFA56DF6F2CEE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 intact-crc:86C35807629F183D|rigid:wJj2xguLwTDTvxYc+Bm5O9Z6dco false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39517 uniprotkb:P39998 intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C intact:EBI-22300|uniprotkb:D3DLN5|ensemblfungi:YEL015W psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:edc3_yeast(display_long)|uniprotkb:EDC3(gene name)|psi-mi:EDC3(display_short)|uniprotkb:LSM16(gene name synonym)|uniprotkb:YEL015W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330788|imex:IM-14275-1533 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 refseq:NP_010901.1|sgd:S000000741|dip:DIP-842N|mint:P39998|ensemblfungi:YEL015W(gene)|ensemblfungi:YEL015W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0033962"(P-body assembly)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR019050|interpro:IPR025762|interpro:IPR036652|rcsb pdb:4BRU|rcsb pdb:6Y3Z|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:062CFA56DF6F2CEE crc64:BF28AE67F9303A73 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 rogid:6NZRCnakEXzFmlF+UujC024p1GE559292 intact-crc:E8167BB1F0766BB5|rigid:W7CbvggTJa+ip1qkPAaZwsh8r5M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39517 uniprotkb:P40023 intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C intact:EBI-22493|uniprotkb:D3DLT4|ensemblfungi:YER035W psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:edc2_yeast(display_long)|uniprotkb:YER035W(locus name)|uniprotkb:EDC2(gene name)|psi-mi:EDC2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330799|imex:IM-14275-1534 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 sgd:S000000837|refseq:NP_010952.3|dip:DIP-5234N|mint:P40023|ensemblfungi:YER035W(gene)|ensemblfungi:YER035W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0032056"(positive regulation of translation in response to stress) psi-mi:"MI:0469"(intact) crc64:062CFA56DF6F2CEE crc64:4D8A461EFD78BFA9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 rogid:nW5oKJQ2vCy2/EmFSke5vZAK/3U559292 intact-crc:6E1879CB57E3E951|rigid:dT9IoY6ZoKj5DAzanBoQOEDEXyE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39517 uniprotkb:P40070 intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330810|imex:IM-14275-1535 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:062CFA56DF6F2CEE crc64:69CAC1F01D5BFA98 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 intact-crc:7AF23986874D2E8B|rigid:IlWIb3O1MeRyg+gFv+Zlzm5YP8k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P45978 uniprotkb:P39517 intact:EBI-16691|ensemblfungi:YPR129W|uniprotkb:D6W4C6 intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C psi-mi:scd6_yeast(display_long)|uniprotkb:P9659.10(orf name)|uniprotkb:YPR129W(locus name)|uniprotkb:SCD6(gene name)|psi-mi:SCD6(display_short) psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330821|imex:IM-14275-1536 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPR129W(gene)|ensemblfungi:YPR129W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:0003729"(mRNA binding)|interpro:IPR025609|refseq:NP_015454.1|sgd:S000006333|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR019050|interpro:IPR025761|interpro:IPR025762|interpro:IPR025768|mint:P45978 sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) - crc64:062CFA56DF6F2CEE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:QRNg1nbLjsxR5twooPvrSPZTWO0559292 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 intact-crc:43A3D6E7A7DF68C8|rigid:6rs8P3GJ5u2nkIH8YYXtZ9lnR3s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53235 uniprotkb:P39517 intact:EBI-23172|uniprotkb:D6VUI9|uniprotkb:Q45U32|ensemblfungi:YGR054W intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C psi-mi:eif2a_yeast(display_long)|uniprotkb:YGR054W(locus name) psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330832|imex:IM-14275-1537 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003286|refseq:NP_011568.3|dip:DIP-5518N|mint:P53235|ensemblfungi:YGR054W(gene)|ensemblfungi:YGR054W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like) sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:F3C2E78504D83418 crc64:062CFA56DF6F2CEE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:x8zDCH5W5GusC7qYd0mDATXhGVI559292 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 intact-crc:E15D09D72F17F255|rigid:taRMAtlqpgRS4ltVtepadbOniAM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39517 uniprotkb:P53297 intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C intact:EBI-12961|uniprotkb:D6VUW2|ensemblfungi:YGR178C psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:pbp1_yeast(display_long)|uniprotkb:PBP1(gene name)|psi-mi:PBP1(display_short)|uniprotkb:MRS16(gene name synonym)|uniprotkb:"Poly(A)-binding protein-binding protein"(gene name synonym)|uniprotkb:YGR178C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330843|imex:IM-14275-1538 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 sgd:S000003410|ensemblfungi:YGR178C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0043621"(protein self-association)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1901524"(regulation of mitophagy)|go:"GO:1904262"(negative regulation of TORC1 signaling)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR025852|ensemblfungi:YGR178C(gene)|refseq:NP_011694.3|mint:P53297|dip:DIP-2464N psi-mi:"MI:0469"(intact) crc64:062CFA56DF6F2CEE crc64:92005F3A2346193E figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 rogid:LtXvbFHbcIwi3NJgeab11QUU2nI559292 intact-crc:666DA5D4199B04B2|rigid:Shlqfl24GuWUxd06p5oYRg8PmS8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39517 uniprotkb:P53550 intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C intact:EBI-270|uniprotkb:B0KZS6|uniprotkb:B0KZU4|uniprotkb:B0KZW2|uniprotkb:B0KZY0|uniprotkb:B0KZY9|uniprotkb:B0KZZ8|uniprotkb:B0L007|uniprotkb:Q6LCS6|uniprotkb:D6W164|ensemblfungi:YNL118C psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:dcp2_yeast(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:Protein PSU1(gene name synonym)|uniprotkb:PSU1(gene name synonym)|uniprotkb:mRNA-decapping enzyme subunit 2(gene name synonym)|uniprotkb:N1917(orf name)|uniprotkb:YNL118C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330854|imex:IM-14275-1539 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 refseq:NP_014281.1|sgd:S000005062|mint:P53550|dip:DIP-969N|ensemblfungi:YNL118C(gene)|ensemblfungi:YNL118C_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0034063"(stress granule assembly)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0098745"(Dcp1-Dcp2 complex)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:2JVB|rcsb pdb:4K6E|rcsb pdb:4KG3|rcsb pdb:4KG4|rcsb pdb:5LM5|rcsb pdb:5LMF|rcsb pdb:5LMG|rcsb pdb:6Y3Z|reactome:R-SCE-430039|reactome:R-SCE-450385|reactome:R-SCE-450513 psi-mi:"MI:0469"(intact) crc64:062CFA56DF6F2CEE crc64:D53CA2C5A546FA4A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 rogid:ER6Kq15/LioWZN7Rw1kAVESWAss559292 intact-crc:8B77267C781C155A|rigid:1GAHlf9VFLt/qKL7KqzxZTFdhtc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53829 uniprotkb:P39517 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330865|imex:IM-14275-1540 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:F3DBABE6AD3C7F3C crc64:062CFA56DF6F2CEE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 intact-crc:B70687CFFE3CE9B5|rigid:2wV8JCEiVpfpDxZoYk2Qy3K2CMs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39517 uniprotkb:P53849 intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C intact:EBI-29244|uniprotkb:D6W0T8|ensemblfungi:YNL255C psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:gis2_yeast(display_long)|uniprotkb:GIS2(gene name)|psi-mi:GIS2(display_short)|uniprotkb:N0852(orf name)|uniprotkb:YNL255C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330876|imex:IM-14275-1541 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 refseq:NP_014144.1|sgd:S000005199|dip:DIP-2669N|mint:P53849|ensemblfungi:YNL255C(gene)|ensemblfungi:YNL255C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045182"(translation regulator activity)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875 psi-mi:"MI:0469"(intact) crc64:062CFA56DF6F2CEE crc64:E72696428F85CA3F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 rogid:kftHFJVi7QRZASmr4hLdALvleR4559292 intact-crc:20C711F52AE0D070|rigid:pCOQs/Waoqu4g5meBYFi0U5irII false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53905 uniprotkb:P39517 intact:EBI-141|uniprotkb:D6W135|ensemblfungi:YNL147W intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C psi-mi:lsm7_yeast(display_long)|uniprotkb:LSM7(gene name)|psi-mi:LSM7(display_short)|uniprotkb:N1202(orf name)|uniprotkb:N1780(orf name)|uniprotkb:YNL147W(locus name) psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330887|imex:IM-14275-1542 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014252.2|sgd:S000005091|mint:P53905|dip:DIP-1419N|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005688"(U6 snRNP)|ensemblfungi:YNL147W(gene)|ensemblfungi:YNL147W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0008033"(tRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR017132(U6 snRNA-associated Sm-like protein LSm7)|interpro:IPR044641|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:EA1D019FC5D1B5C5 crc64:062CFA56DF6F2CEE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:LBD0KzUVuBCAGeCVPV5bSS8Hodg559292 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 intact-crc:69C4DFC90122AF09|rigid:aeW9DtYTQJycr/mkBr7OKPiTzwU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P57743 uniprotkb:P39517 intact:EBI-10227|uniprotkb:Q05176|uniprotkb:Q06759|uniprotkb:D6VZ73|ensemblfungi:YLR438C-A intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C psi-mi:lsm3_yeast(display_long)|uniprotkb:LSM3(gene name)|psi-mi:LSM3(display_short)|uniprotkb:SMX4(gene name synonym)|uniprotkb:USS2(gene name synonym)|uniprotkb:YLR438C-A(locus name)|uniprotkb:SmX4 protein(gene name synonym) psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330898|imex:IM-14275-1543 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006434|ensemblfungi:YLR438C-A(gene)|ensemblfungi:YLR438C-A_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034105|interpro:IPR040002|rcsb pdb:3BW1|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:4N0A|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039|rcsb pdb:4M75|refseq:NP_013543.3|dip:DIP-2587N|mint:P57743 sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:787084EF6A5945B7 crc64:062CFA56DF6F2CEE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nYl7At1SnlSwN+nWr1F1xm0tdDE559292 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 intact-crc:BABC7811C245D086|rigid:xeIjGx4wopQGJaEJxi4zg/o+9ck false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39517 uniprotkb:Q06406 intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C intact:EBI-196|uniprotkb:D6VT10|ensemblfungi:YDR378C psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:lsm6_yeast(display_long)|uniprotkb:LSM6(gene name)|psi-mi:LSM6(display_short)|uniprotkb:D9481.18(orf name)|uniprotkb:YDR378C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330909|imex:IM-14275-1544 author score:97.90 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 refseq:NP_010666.2|sgd:S000002786|mint:Q06406|dip:DIP-1418N|ensemblfungi:YDR378C(gene)|ensemblfungi:YDR378C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0008033"(tRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:062CFA56DF6F2CEE crc64:74FE40A4509CEF33 figure legend:tables S3 and S4|author-confidence:97.90|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 rogid:JQtrhOkngO6APIPCFMRnKogB96c559292 intact-crc:2513AB8C34B4F074|rigid:Bw0UudTBhF+r+7NDAZhAZsTR6iM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39517 uniprotkb:Q12517 intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C intact:EBI-38519|uniprotkb:D6W1S0|ensemblfungi:YOL149W psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:dcp1_yeast(display_long)|uniprotkb:DCP1(gene name)|psi-mi:DCP1(display_short)|uniprotkb:YOL149W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330920|imex:IM-14275-1545 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 refseq:NP_014492.1|sgd:S000005509|mint:Q12517|dip:DIP-1288N|ensemblfungi:YOL149W(gene)|ensemblfungi:YOL149W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0098745"(Dcp1-Dcp2 complex)|interpro:IPR010334(Dcp1-like decapping)|rcsb pdb:1Q67|rcsb pdb:6Y3Z|reactome:R-SCE-430039|reactome:R-SCE-450385|reactome:R-SCE-450513 psi-mi:"MI:0469"(intact) crc64:062CFA56DF6F2CEE crc64:8456B1C96C121C4D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 rogid:CXLHokbNWY54t80lw79Or4Wmb1g559292 intact-crc:2BB6B0078FF6EC3B|rigid:grc0Vs2q0N+xFPFQnLuXWKhr4bE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20434 uniprotkb:P39520 intact:EBI-15781|uniprotkb:Q02121|ensemblfungi:YBR154C|uniprotkb:D6VQE9 intact:EBI-9054|ensemblfungi:YLR223C|uniprotkb:D6VYM3 psi-mi:rpab1_yeast(display_long)|uniprotkb:RPB5(gene name)|psi-mi:RPB5(display_short)|uniprotkb:YBR154C(locus name)|uniprotkb:YBR1204(orf name)|uniprotkb:RPA7(gene name synonym)|uniprotkb:RPC9(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide(gene name synonym)|uniprotkb:ABC27(gene name synonym) psi-mi:ifh1_yeast(display_long)|uniprotkb:RRP3(gene name synonym)|uniprotkb:L8083.9(orf name)|uniprotkb:YLR223C(locus name)|uniprotkb:IFH1(gene name)|psi-mi:IFH1(display_short)|uniprotkb:Ribosomal RNA-processing protein 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330931|imex:IM-14275-1546 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|rcsb pdb:1WCM|rcsb pdb:1Y1V|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|rcsb pdb:2B63|rcsb pdb:2B8K|interpro:IPR020608|interpro:IPR020609|rcsb pdb:2E2H|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:1DZF|rcsb pdb:1I3Q|rcsb pdb:2E2I|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:5M5Y|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6H67|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:2E2J|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|ensemblfungi:YBR154C(gene)|ensemblfungi:YBR154C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4V1M|rcsb pdb:2JA5|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2JA6|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:2JA7|rcsb pdb:3GTG|rcsb pdb:2JA8|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:2NVQ|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4YM7|rcsb pdb:5C3E|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5G5L|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6H68|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|rcsb pdb:6UQ2|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-77075|reactome:R-SCE-9018519|refseq:NP_009712.1|sgd:S000000358|dip:DIP-71N|mint:P20434 refseq:NP_013324.1|sgd:S000004213|ensemblfungi:YLR223C(gene)|ensemblfungi:YLR223C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006348"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032545"(CURI complex)|go:"GO:0060963"(positive regulation of ribosomal protein gene transcription by RNA polymerase II)|interpro:IPR018837|dip:DIP-905N|mint:P39520 psi-mi:"MI:0469"(intact) crc64:2A15F7114D69D829 - figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:j/jAJ2fXWf4ebK1aWTWrKERGUpM559292 rogid:YXvLJNm3gbTL7XOC8Q3t8qzkS7M559292 intact-crc:3456874B41156C22|rigid:2kWqiYxcnsHAK161EI755WnQnX0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39524 uniprotkb:P32660 intact:EBI-3106|uniprotkb:D6VPJ2|ensemblfungi:YAL026C intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W psi-mi:atc3_yeast(display_long)|uniprotkb:DRS2(gene name)|psi-mi:DRS2(display_short)|uniprotkb:FUN38(orf name)|uniprotkb:YAL026C(locus name) psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330942|imex:IM-14275-1547 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009376.2|sgd:S000000024|dip:DIP-2216N|mint:P39524|ensemblfungi:YAL026C(gene)|ensemblfungi:YAL026C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|go:"GO:1990530"(Cdc50p-Drs2p complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:6PSX|rcsb pdb:6PSY|rcsb pdb:6ROH|rcsb pdb:6ROI|rcsb pdb:6ROJ|rcsb pdb:7OH4|rcsb pdb:7OH5|rcsb pdb:7OH6|rcsb pdb:7OH7|reactome:R-SCE-6798695|reactome:R-SCE-936837 sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) psi-mi:"MI:0469"(intact) crc64:5745B92901F8E1AE crc64:3CC3FBA8ADDE8960 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:qJ8uK7dznIqyjVwjbw/VGn5Bo+4559292 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 intact-crc:B5CB9DFC55D3980D|rigid:DKX0A3qhBPsxlbimHJhITIPgy/E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39524 uniprotkb:Q12057 intact:EBI-3106|uniprotkb:D6VPJ2|ensemblfungi:YAL026C intact:EBI-29838|uniprotkb:D6W2G4|ensemblfungi:YOR104W psi-mi:atc3_yeast(display_long)|uniprotkb:DRS2(gene name)|psi-mi:DRS2(display_short)|uniprotkb:FUN38(orf name)|uniprotkb:YAL026C(locus name) psi-mi:pin2_yeast(display_long)|uniprotkb:PIN2(gene name)|psi-mi:PIN2(display_short)|uniprotkb:YOR3214W(orf name)|uniprotkb:YOR104W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330953|imex:IM-14275-1548 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009376.2|sgd:S000000024|dip:DIP-2216N|mint:P39524|ensemblfungi:YAL026C(gene)|ensemblfungi:YAL026C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|go:"GO:1990530"(Cdc50p-Drs2p complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:6PSX|rcsb pdb:6PSY|rcsb pdb:6ROH|rcsb pdb:6ROI|rcsb pdb:6ROJ|rcsb pdb:7OH4|rcsb pdb:7OH5|rcsb pdb:7OH6|rcsb pdb:7OH7|reactome:R-SCE-6798695|reactome:R-SCE-936837 sgd:S000005630|refseq:NP_014747.1|dip:DIP-4459N|mint:Q12057|ensemblfungi:YOR104W(gene)|ensemblfungi:YOR104W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|interpro:IPR037504 psi-mi:"MI:0469"(intact) crc64:5745B92901F8E1AE - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:qJ8uK7dznIqyjVwjbw/VGn5Bo+4559292 rogid:Zk6iUcpP++MEXuhKZ79TMOYQYqM559292 intact-crc:DE7F757BFA92AD09|rigid:2rJIMkCxH9dCSxWbPVlXJLYICqI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39525 uniprotkb:P52490 intact:EBI-4467|uniprotkb:D3DLW6|ensemblfungi:YER061C intact:EBI-19777|uniprotkb:D6VS79|ensemblfungi:YDR092W psi-mi:cem1_yeast(display_long)|uniprotkb:CEM1(gene name)|psi-mi:CEM1(display_short)|uniprotkb:YER061C(locus name)|uniprotkb:Beta-ketoacyl-ACP synthase homolog(gene name synonym) psi-mi:ubc13_yeast(display_long)|uniprotkb:UBC13(gene name)|psi-mi:UBC13(display_short)|uniprotkb:YDR092W(locus name)|uniprotkb:YD6652.04(orf name)|uniprotkb:Ubiquitin-protein ligase 13(gene name synonym)|uniprotkb:Ubiquitin carrier protein 13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 13(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330964|imex:IM-14275-1549 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010983.2|sgd:S000000863|mint:P39525|dip:DIP-5342N|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020841|ensemblfungi:YER061C(gene)|ensemblfungi:YER061C_mRNA(transcript)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006633"(fatty acid biosynthetic process)|interpro:IPR000794(Beta-ketoacyl synthase)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal) sgd:S000002499|ensemblfungi:YDR092W(gene)|ensemblfungi:YDR092W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006301"(postreplication repair)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0044395"(protein targeting to vacuolar membrane)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1JAT|rcsb pdb:1JBB|rcsb pdb:2GMI|rcsb pdb:4FH1|rcsb pdb:5OJW|reactome:R-SCE-8866654|reactome:R-SCE-9020702|reactome:R-SCE-9646399|reactome:R-SCE-983168|refseq:NP_010377.3|dip:DIP-5486N|mint:P52490 psi-mi:"MI:0469"(intact) - crc64:445558F8F193275B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rP4D8elWMkhgyJRH9+XOQgBkScE559292 rogid:5nTtjUZ2IpzHhrj1UU6NlaRW53k559292 intact-crc:47B904E614BDDF2C|rigid:2UbQa7lSRcEQMy/0XLd4+Fw8R4Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P39543 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-26193|uniprotkb:D6VVZ9|ensemblfungi:YJL192C psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:sop4_yeast(display_long)|uniprotkb:Suppressor of PMA1-7 protein 4(gene name synonym)|uniprotkb:YJL192C(locus name)|uniprotkb:J0351(orf name)|uniprotkb:SOP4(gene name)|psi-mi:SOP4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330975|imex:IM-14275-1550 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 sgd:S000003728|refseq:NP_012343.1|mint:P39543|dip:DIP-5094N|ensemblfungi:YJL192C(gene)|ensemblfungi:YJL192C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR031395|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:a+WulVpSm4gdxpcINNvDPLR2rZI559292 intact-crc:F084193A50163ED4|rigid:2g76qV3u7x+JmnYBaf3NwJ21cX4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17064 uniprotkb:P39543 intact:EBI-2047850|uniprotkb:D3DLV9|ensemblfungi:YER056C intact:EBI-26193|uniprotkb:D6VVZ9|ensemblfungi:YJL192C psi-mi:fcy2_yeast(display_long)|uniprotkb:Cytosine/purine transport protein FCY2(gene name synonym)|uniprotkb:Fluorocytosine resistance protein 2(gene name synonym)|uniprotkb:YER056C(locus name)|uniprotkb:FCY2(gene name)|psi-mi:FCY2(display_short) psi-mi:sop4_yeast(display_long)|uniprotkb:Suppressor of PMA1-7 protein 4(gene name synonym)|uniprotkb:YJL192C(locus name)|uniprotkb:J0351(orf name)|uniprotkb:SOP4(gene name)|psi-mi:SOP4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330986|imex:IM-14275-1551 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010976.1|sgd:S000000858|dip:DIP-7593N|mint:P17064|ensemblfungi:YER056C(gene)|ensemblfungi:YER056C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015205"(nucleobase transmembrane transporter activity)|go:"GO:0015212"(cytidine transmembrane transporter activity)|go:"GO:0015856"(cytosine transport)|go:"GO:0015861"(cytidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:0072530"(purine-containing compound transmembrane transport)|interpro:IPR001248(Permease for cytosine/purines, uracil, thiamine, allantoin)|interpro:IPR012681(Nucleobase cation symporter-1, NCS1)|interpro:IPR026030 sgd:S000003728|refseq:NP_012343.1|mint:P39543|dip:DIP-5094N|ensemblfungi:YJL192C(gene)|ensemblfungi:YJL192C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR031395|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:797s9w2xSSBhW0uTLcFEESToqgg559292 rogid:a+WulVpSm4gdxpcINNvDPLR2rZI559292 intact-crc:6B38D31D4F3FC23A|rigid:J/pOGIBUIQe8UqbBXuHqt5uNUM8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39543 uniprotkb:P38084 intact:EBI-26193|uniprotkb:D6VVZ9|ensemblfungi:YJL192C intact:EBI-3414|uniprotkb:D6VQ67|ensemblfungi:YBR068C psi-mi:sop4_yeast(display_long)|uniprotkb:Suppressor of PMA1-7 protein 4(gene name synonym)|uniprotkb:YJL192C(locus name)|uniprotkb:J0351(orf name)|uniprotkb:SOP4(gene name)|psi-mi:SOP4(display_short) psi-mi:bap2_yeast(display_long)|uniprotkb:Branched-chain amino-acid permease 2(gene name synonym)|uniprotkb:BAP2(gene name)|psi-mi:BAP2(display_short)|uniprotkb:YBR068C(locus name)|uniprotkb:YBR0629(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6330997|imex:IM-14275-1552 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003728|refseq:NP_012343.1|mint:P39543|dip:DIP-5094N|ensemblfungi:YJL192C(gene)|ensemblfungi:YJL192C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR031395|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX sgd:S000000272|refseq:NP_009624.4|dip:DIP-4910N|mint:P38084|ensemblfungi:YBR068C(gene)|ensemblfungi:YBR068C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015192"(L-phenylalanine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098713"(leucine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) psi-mi:"MI:0469"(intact) - crc64:B87FD6A7464E07F5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:a+WulVpSm4gdxpcINNvDPLR2rZI559292 rogid:7Fw7+M5mBikZBztHE2tSDpvBi/M559292 intact-crc:0202D9ECB35B2179|rigid:8SmBc4cbojr5pWV9/FooZp/JnKw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39543 uniprotkb:P38264 intact:EBI-26193|uniprotkb:D6VVZ9|ensemblfungi:YJL192C intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 psi-mi:sop4_yeast(display_long)|uniprotkb:Suppressor of PMA1-7 protein 4(gene name synonym)|uniprotkb:YJL192C(locus name)|uniprotkb:J0351(orf name)|uniprotkb:SOP4(gene name)|psi-mi:SOP4(display_short) psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331008|imex:IM-14275-1553 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003728|refseq:NP_012343.1|mint:P39543|dip:DIP-5094N|ensemblfungi:YJL192C(gene)|ensemblfungi:YJL192C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR031395|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:a+WulVpSm4gdxpcINNvDPLR2rZI559292 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 intact-crc:E7921BEC8D368219|rigid:LRlpI81qNMTVgWwyE2jNDsGOEZY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39543 uniprotkb:P40540 intact:EBI-26193|uniprotkb:D6VVZ9|ensemblfungi:YJL192C intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C psi-mi:sop4_yeast(display_long)|uniprotkb:Suppressor of PMA1-7 protein 4(gene name synonym)|uniprotkb:YJL192C(locus name)|uniprotkb:J0351(orf name)|uniprotkb:SOP4(gene name)|psi-mi:SOP4(display_short) psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331019|imex:IM-14275-1554 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003728|refseq:NP_012343.1|mint:P39543|dip:DIP-5094N|ensemblfungi:YJL192C(gene)|ensemblfungi:YJL192C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR031395|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) - crc64:6DBEEEE7722203B0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:a+WulVpSm4gdxpcINNvDPLR2rZI559292 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 intact-crc:BDE3D3D429337EBD|rigid:5u9NQ+s+mPAd1P4FNHZnHkUFzGE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02774 uniprotkb:P39543 intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 intact:EBI-26193|uniprotkb:D6VVZ9|ensemblfungi:YJL192C psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:sop4_yeast(display_long)|uniprotkb:Suppressor of PMA1-7 protein 4(gene name synonym)|uniprotkb:YJL192C(locus name)|uniprotkb:J0351(orf name)|uniprotkb:SOP4(gene name)|psi-mi:SOP4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331030|imex:IM-14275-1555 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 sgd:S000003728|refseq:NP_012343.1|mint:P39543|dip:DIP-5094N|ensemblfungi:YJL192C(gene)|ensemblfungi:YJL192C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR031395|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 rogid:a+WulVpSm4gdxpcINNvDPLR2rZI559292 intact-crc:05143B669F6D893C|rigid:aWP6XGienSEEQoPg0uME987rsHA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39543 uniprotkb:Q02785 intact:EBI-26193|uniprotkb:D6VVZ9|ensemblfungi:YJL192C intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:sop4_yeast(display_long)|uniprotkb:Suppressor of PMA1-7 protein 4(gene name synonym)|uniprotkb:YJL192C(locus name)|uniprotkb:J0351(orf name)|uniprotkb:SOP4(gene name)|psi-mi:SOP4(display_short) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331041|imex:IM-14275-1556 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003728|refseq:NP_012343.1|mint:P39543|dip:DIP-5094N|ensemblfungi:YJL192C(gene)|ensemblfungi:YJL192C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR031395|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:a+WulVpSm4gdxpcINNvDPLR2rZI559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:96CED728794FB801|rigid:Hr/KOwcXNO4hYj0rYNFaA5xCXC8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39543 uniprotkb:Q06144 intact:EBI-26193|uniprotkb:D6VVZ9|ensemblfungi:YJL192C intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:sop4_yeast(display_long)|uniprotkb:Suppressor of PMA1-7 protein 4(gene name synonym)|uniprotkb:YJL192C(locus name)|uniprotkb:J0351(orf name)|uniprotkb:SOP4(gene name)|psi-mi:SOP4(display_short) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331052|imex:IM-14275-1557 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003728|refseq:NP_012343.1|mint:P39543|dip:DIP-5094N|ensemblfungi:YJL192C(gene)|ensemblfungi:YJL192C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR031395|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:2F474503CAB7C195 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:a+WulVpSm4gdxpcINNvDPLR2rZI559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 intact-crc:8BEE74932BFBD170|rigid:ytib82RAQEZHqm8BUCk5BLX3Ey8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22137 uniprotkb:P39676 intact:EBI-4766|uniprotkb:D6VTU9|ensemblfungi:YGL206C intact:EBI-6905|uniprotkb:Q6B1W6|uniprotkb:Q9C1R6|uniprotkb:D6VV14|ensemblfungi:YGR234W psi-mi:clh_yeast(display_long)|uniprotkb:CHC1(gene name)|psi-mi:CHC1(display_short)|uniprotkb:YGL206C(locus name) psi-mi:fhp_yeast(display_long)|uniprotkb:YHB1(gene name)|psi-mi:YHB1(display_short)|uniprotkb:YHB(gene name synonym)|uniprotkb:YGR234W(locus name)|uniprotkb:G8572(orf name)|uniprotkb:Flavohemoglobin(gene name synonym)|uniprotkb:Hemoglobin-like protein(gene name synonym)|uniprotkb:Nitric oxide dioxygenase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331063|imex:IM-14275-1558 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011309.1|sgd:S000003174|dip:DIP-2279N|mint:P22137|ensemblfungi:YGL206C(gene)|ensemblfungi:YGL206C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0071439"(clathrin complex)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-432720|reactome:R-SCE-437239|reactome:R-SCE-8856828|reactome:R-SCE-8866427|reactome:R-SCE-8964038 refseq:NP_011750.1|sgd:S000003466|mint:P39676|dip:DIP-1355N|ensemblfungi:YGR234W(gene)|ensemblfungi:YGR234W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0008941"(nitric oxide dioxygenase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016966"(nitric oxide reductase activity)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046210"(nitric oxide catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0071500"(cellular response to nitrosative stress)|go:"GO:0071949"(FAD binding)|go:"GO:1902170"(cellular response to reactive nitrogen species)|interpro:IPR000971(Globin, subset)|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023950|interpro:IPR039261 psi-mi:"MI:0469"(intact) crc64:622F3083DF2FE315 crc64:8AF1DE3280220D56 figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SAN6H3nVFozXZyTiRLaljMcIKIA559292 rogid:IfSyxMXBw3eqwWjAFb87dab9Ixo559292 intact-crc:9DBFEFACF9680BC0|rigid:sFxC0pu40F56zTWuxMmZpVz17Bo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39705 uniprotkb:Q06142 intact:EBI-20731|uniprotkb:D6VPL6|ensemblfungi:YAR002W intact:EBI-9145|ensemblfungi:YLR347C|uniprotkb:D6VYY6 psi-mi:nup60_yeast(display_long)|uniprotkb:YAR002W(locus name)|uniprotkb:NUP60(gene name)|psi-mi:NUP60(display_short)|uniprotkb:FUN17(gene name synonym)|uniprotkb:Nuclear pore protein NUP60(gene name synonym) psi-mi:imb1_yeast(display_long)|uniprotkb:KAP95(gene name)|psi-mi:KAP95(display_short)|uniprotkb:YLR347C(locus name)|uniprotkb:L8300.15(orf name)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Karyopherin-95(gene name synonym)|uniprotkb:Importin-95(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331074|imex:IM-14275-1559 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009401.1|sgd:S000000063|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0051276"(chromosome organization)|go:"GO:0060188"(regulation of protein desumoylation)|interpro:IPR034432|go:"GO:0031965"(nuclear membrane)|ensemblfungi:YAR002W(gene)|ensemblfungi:YAR002W_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|dip:DIP-5821N|mint:P39705 rcsb pdb:3EA5|rcsb pdb:3ND2|rcsb pdb:5OWU|reactome:R-SCE-2995383|reactome:R-SCE-6798695|ensemblfungi:YLR347C(gene)|ensemblfungi:YLR347C_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|rcsb pdb:2BKU|go:"GO:0006612"(protein targeting to membrane)|refseq:NP_013451.1|sgd:S000004339|dip:DIP-2357N|mint:Q06142 psi-mi:"MI:0469"(intact) crc64:B9A28494A358A3E3 crc64:ED530F5313E75B06 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ftY1eAVEdnibo+k3w+veEWA6zx4559292 rogid:ebWeXaUKiBFWgjdv9s2pz1GIqgI559292 intact-crc:8C228C5C6A2BD994|rigid:Wh/2QCElpsQJBhWHeQ0A8Y+Ei0I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39742 uniprotkb:P33754 intact:EBI-16651|ensemblfungi:YLR292C|uniprotkb:D6VYT8 intact:EBI-16647|ensemblfungi:YBR171W|uniprotkb:D6VQG7 psi-mi:sec72_yeast(display_long)|uniprotkb:SEC67(gene name synonym)|uniprotkb:SIM2(gene name synonym)|uniprotkb:L8003.18(orf name)|uniprotkb:YLR292C(locus name)|uniprotkb:SEC72(gene name)|psi-mi:SEC72(display_short)|uniprotkb:Sec62/63 complex 23 kDa subunit(gene name synonym) psi-mi:sec66_yeast(display_long)|uniprotkb:SEC71(gene name synonym)|uniprotkb:YBR1232(orf name)|uniprotkb:YBR171W(locus name)|uniprotkb:SEC66(gene name)|psi-mi:SEC66(display_short)|uniprotkb:HSS1(gene name synonym)|uniprotkb:Sec62/63 complex 31.5 kDa subunit(gene name synonym)|uniprotkb:Protein HSS1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331085|imex:IM-14275-1560 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR292C(gene)|ensemblfungi:YLR292C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAJ|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|rcsb pdb:7KAO|rcsb pdb:7KAP|refseq:NP_013395.1|sgd:S000004283|dip:DIP-2491N|mint:P39742 refseq:NP_009730.3|ensemblfungi:YBR171W(gene)|ensemblfungi:YBR171W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030447"(filamentous growth)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0071944"(cell periphery)|interpro:IPR018624|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|sgd:S000000375|dip:DIP-1694N|mint:P33754 psi-mi:"MI:0469"(intact) - crc64:E2A8BB4994A227D4 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6m5FOSsQ87OrJRnqo2hkjAtqkg559292 rogid:KvIn7euv+AwTIngwnUh/lmdLyaw559292 intact-crc:CB8C0013B35F7DBE|rigid:g2yYcInRgNm+UGwyB3RNPtg8cF0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39743 uniprotkb:P37370 intact:EBI-14500|uniprotkb:D6VT22|ensemblfungi:YDR388W intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C psi-mi:rv167_yeast(display_long)|uniprotkb:D9509.8(orf name)|uniprotkb:YDR388W(locus name)|uniprotkb:RVS167(gene name)|psi-mi:RVS167(display_short) psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331096|imex:IM-14275-1561 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR388W(gene)|ensemblfungi:YDR388W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006897"(endocytosis)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031097"(medial cortex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR036028|go:"GO:1990528"(Rvs161p-Rvs167p complex)|refseq:NP_010676.1|sgd:S000002796|mint:P39743|dip:DIP-770N refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370 psi-mi:"MI:0469"(intact) crc64:3F0AB53EBCC95A5B crc64:24C7522D5B1CA1C8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:w3CZzhpvanHbodoFFlzkAHnsQyA559292 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 intact-crc:52B132A36A2556C1|rigid:2YMr8qj3LirUZCT2+dWo2hPvdJE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39743 uniprotkb:P38328 intact:EBI-14500|uniprotkb:D6VT22|ensemblfungi:YDR388W intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C psi-mi:rv167_yeast(display_long)|uniprotkb:D9509.8(orf name)|uniprotkb:YDR388W(locus name)|uniprotkb:RVS167(gene name)|psi-mi:RVS167(display_short) psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331107|imex:IM-14275-1562 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR388W(gene)|ensemblfungi:YDR388W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006897"(endocytosis)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031097"(medial cortex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR036028|go:"GO:1990528"(Rvs161p-Rvs167p complex)|refseq:NP_010676.1|sgd:S000002796|mint:P39743|dip:DIP-770N sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:3F0AB53EBCC95A5B crc64:D75C6BB8EC35EEDF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:w3CZzhpvanHbodoFFlzkAHnsQyA559292 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 intact-crc:D65BC5A997A131F1|rigid:BEiLuLPFmAl5DLuYyw7KNN3641I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39743 uniprotkb:P39743 intact:EBI-14500|uniprotkb:D6VT22|ensemblfungi:YDR388W intact:EBI-14500|uniprotkb:D6VT22|ensemblfungi:YDR388W psi-mi:rv167_yeast(display_long)|uniprotkb:D9509.8(orf name)|uniprotkb:YDR388W(locus name)|uniprotkb:RVS167(gene name)|psi-mi:RVS167(display_short) psi-mi:rv167_yeast(display_long)|uniprotkb:D9509.8(orf name)|uniprotkb:YDR388W(locus name)|uniprotkb:RVS167(gene name)|psi-mi:RVS167(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331118|imex:IM-14275-1563 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR388W(gene)|ensemblfungi:YDR388W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006897"(endocytosis)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031097"(medial cortex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR036028|go:"GO:1990528"(Rvs161p-Rvs167p complex)|refseq:NP_010676.1|sgd:S000002796|mint:P39743|dip:DIP-770N ensemblfungi:YDR388W(gene)|ensemblfungi:YDR388W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006897"(endocytosis)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031097"(medial cortex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR036028|go:"GO:1990528"(Rvs161p-Rvs167p complex)|refseq:NP_010676.1|sgd:S000002796|mint:P39743|dip:DIP-770N psi-mi:"MI:0469"(intact) crc64:3F0AB53EBCC95A5B crc64:3F0AB53EBCC95A5B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:w3CZzhpvanHbodoFFlzkAHnsQyA559292 rogid:w3CZzhpvanHbodoFFlzkAHnsQyA559292 intact-crc:999F54D8BE178BA3|rigid:Ly6+uiitteknrVs6WCyx3TKg+20 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39744 uniprotkb:P21304 intact:EBI-29259|uniprotkb:Q08625|uniprotkb:D6W2R2|ensemblfungi:YOR206W intact:EBI-14328|uniprotkb:D6VYJ9|ensemblfungi:YLR196W psi-mi:noc2_yeast(display_long)|uniprotkb:YOX001(orf name)|uniprotkb:YOR206W(locus name)|uniprotkb:NOC2(gene name)|psi-mi:NOC2(display_short) psi-mi:pwp1_yeast(display_long)|uniprotkb:L8167.10(orf name)|uniprotkb:YLR196W(locus name)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331129|imex:IM-14275-1564 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014849.3|sgd:S000005732|dip:DIP-4559N|mint:P39744|ensemblfungi:YOR206W(gene)|ensemblfungi:YOR206W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR005343(Protein of unknown function UPF0120) refseq:NP_013297.1|sgd:S000004186|ensemblfungi:YLR196W(gene)|ensemblfungi:YLR196W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR044285|mint:P21304|dip:DIP-4203N psi-mi:"MI:0469"(intact) crc64:48C3B9AE076B9B8F crc64:FC0189B289494AB5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:d5I8KJOSG63bZ/Pt+XvKdy/SWws559292 rogid:Q1nPXtlkpIw8JosaiYX0PSVNaSw559292 intact-crc:B7029EEA183CDB25|rigid:jg6+OCLMShiM1kB9Vd/0gRfnq1o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39744 uniprotkb:P24783 intact:EBI-29259|uniprotkb:Q08625|uniprotkb:D6W2R2|ensemblfungi:YOR206W intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W psi-mi:noc2_yeast(display_long)|uniprotkb:YOX001(orf name)|uniprotkb:YOR206W(locus name)|uniprotkb:NOC2(gene name)|psi-mi:NOC2(display_short) psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331140|imex:IM-14275-1565 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014849.3|sgd:S000005732|dip:DIP-4559N|mint:P39744|ensemblfungi:YOR206W(gene)|ensemblfungi:YOR206W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR005343(Protein of unknown function UPF0120) sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) crc64:48C3B9AE076B9B8F crc64:30FE3D4C7E653120 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:d5I8KJOSG63bZ/Pt+XvKdy/SWws559292 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 intact-crc:3AB248100FA93D87|rigid:HPgwN5PE3T4PHMdEakjTgeGUk5c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43586 uniprotkb:P39744 intact:EBI-22906|uniprotkb:D6VTN1|ensemblfungi:YFR001W intact:EBI-29259|uniprotkb:Q08625|uniprotkb:D6W2R2|ensemblfungi:YOR206W psi-mi:loc1_yeast(display_long)|uniprotkb:YFR001W(locus name)|uniprotkb:LOC1(gene name)|psi-mi:LOC1(display_short)|uniprotkb:Localization of ASH1 mRNA protein 1(gene name synonym) psi-mi:noc2_yeast(display_long)|uniprotkb:YOX001(orf name)|uniprotkb:YOR206W(locus name)|uniprotkb:NOC2(gene name)|psi-mi:NOC2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331151|imex:IM-14275-1566 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116656.1|sgd:S000001897|dip:DIP-6615N|mint:P43586|ensemblfungi:YFR001W(gene)|ensemblfungi:YFR001W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051028"(mRNA transport)|go:"GO:0101031"(chaperone complex)|interpro:IPR037650|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)") refseq:NP_014849.3|sgd:S000005732|dip:DIP-4559N|mint:P39744|ensemblfungi:YOR206W(gene)|ensemblfungi:YOR206W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR005343(Protein of unknown function UPF0120) psi-mi:"MI:0469"(intact) crc64:69970294E9C980F9 crc64:48C3B9AE076B9B8F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9z0K05pOV8o7bqozFWieGjfs/FM559292 rogid:d5I8KJOSG63bZ/Pt+XvKdy/SWws559292 intact-crc:39E9F48AA5CA119F|rigid:It1Pz+JU2zdRV+KPtiTvvVTXa54 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53551 uniprotkb:P39744 intact:EBI-8064|uniprotkb:Q6Q5R6|uniprotkb:D6W3P0|ensemblfungi:YPL127C intact:EBI-29259|uniprotkb:Q08625|uniprotkb:D6W2R2|ensemblfungi:YOR206W psi-mi:h1_yeast(display_long)|uniprotkb:HHO1(gene name)|psi-mi:HHO1(display_short)|uniprotkb:LPI17C(orf name)|uniprotkb:YPL127C(locus name) psi-mi:noc2_yeast(display_long)|uniprotkb:YOX001(orf name)|uniprotkb:YOR206W(locus name)|uniprotkb:NOC2(gene name)|psi-mi:NOC2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331162|imex:IM-14275-1567 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015198.1|sgd:S000006048|mint:P53551|dip:DIP-6587N|ensemblfungi:YPL127C(gene)|ensemblfungi:YPL127C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0097100"(supercoiled DNA binding)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1UHM|rcsb pdb:1USS|rcsb pdb:1UST|rcsb pdb:1YQA refseq:NP_014849.3|sgd:S000005732|dip:DIP-4559N|mint:P39744|ensemblfungi:YOR206W(gene)|ensemblfungi:YOR206W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR005343(Protein of unknown function UPF0120) psi-mi:"MI:0469"(intact) crc64:B0C53AC186E49F96 crc64:48C3B9AE076B9B8F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dPMYSAq1Cr7pfGGNgb3GDp3LnsQ559292 rogid:d5I8KJOSG63bZ/Pt+XvKdy/SWws559292 intact-crc:58F5EF578C2306C2|rigid:4xfIKBkWiW/5a1qKeKWt5Aim3x0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53874 uniprotkb:P39744 intact:EBI-19873|uniprotkb:D6W101|ensemblfungi:YNL186W intact:EBI-29259|uniprotkb:Q08625|uniprotkb:D6W2R2|ensemblfungi:YOR206W psi-mi:ubp10_yeast(display_long)|uniprotkb:UBP10(gene name)|psi-mi:UBP10(display_short)|uniprotkb:YNL186W(locus name)|uniprotkb:N1619(orf name)|uniprotkb:Ubiquitin-specific-processing protease 10(gene name synonym)|uniprotkb:Deubiquitinating enzyme 10(gene name synonym)|uniprotkb:Disrupter of telomere silencing protein 4(gene name synonym)|uniprotkb:Ubiquitin thioesterase 10(gene name synonym)|uniprotkb:DOT4(gene name synonym) psi-mi:noc2_yeast(display_long)|uniprotkb:YOX001(orf name)|uniprotkb:YOR206W(locus name)|uniprotkb:NOC2(gene name)|psi-mi:NOC2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331173|imex:IM-14275-1568 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014213.2|sgd:S000005130|ensemblfungi:YNL186W(gene)|ensemblfungi:YNL186W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0043596"(nuclear replication fork)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|rcsb pdb:6RR0|dip:DIP-6664N|mint:P53874 refseq:NP_014849.3|sgd:S000005732|dip:DIP-4559N|mint:P39744|ensemblfungi:YOR206W(gene)|ensemblfungi:YOR206W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR005343(Protein of unknown function UPF0120) psi-mi:"MI:0469"(intact) - crc64:48C3B9AE076B9B8F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Z1rRAI9RLgHeGd7QwLbrf51v5LY559292 rogid:d5I8KJOSG63bZ/Pt+XvKdy/SWws559292 intact-crc:2389666A0CC254FE|rigid:4oTCkgHhvZo9kDaGLjzx0ObJm0s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06205 uniprotkb:P39744 intact:EBI-6956|uniprotkb:D6VZ83|ensemblfungi:YLR449W intact:EBI-29259|uniprotkb:Q08625|uniprotkb:D6W2R2|ensemblfungi:YOR206W psi-mi:fkbp4_yeast(display_long)|uniprotkb:FPR4(gene name)|psi-mi:FPR4(display_short)|uniprotkb:YLR449W(locus name)|uniprotkb:L9324.3(orf name)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Histone proline isomerase(gene name synonym) psi-mi:noc2_yeast(display_long)|uniprotkb:YOX001(orf name)|uniprotkb:YOR206W(locus name)|uniprotkb:NOC2(gene name)|psi-mi:NOC2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331184|imex:IM-14275-1569 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004441|refseq:NP_013554.3|dip:DIP-909N|mint:Q06205|ensemblfungi:YLR449W(gene)|ensemblfungi:YLR449W_mRNA(transcript)|go:"GO:0000412"(histone peptidyl-prolyl isomerization)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR023566|interpro:IPR041232|rcsb pdb:4BF8 refseq:NP_014849.3|sgd:S000005732|dip:DIP-4559N|mint:P39744|ensemblfungi:YOR206W(gene)|ensemblfungi:YOR206W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR005343(Protein of unknown function UPF0120) psi-mi:"MI:0469"(intact) crc64:CF90C6714F04572E crc64:48C3B9AE076B9B8F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rDmDSGEgRbtgkLBoJTzmzxxY7B4559292 rogid:d5I8KJOSG63bZ/Pt+XvKdy/SWws559292 intact-crc:CA04B94DB997837C|rigid:tAo8501TKTF6IOq+5vjoJSEXae8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39744 uniprotkb:Q08235 intact:EBI-29259|uniprotkb:Q08625|uniprotkb:D6W2R2|ensemblfungi:YOR206W intact:EBI-3775|uniprotkb:D6W1Z1|ensemblfungi:YOL077C psi-mi:noc2_yeast(display_long)|uniprotkb:YOX001(orf name)|uniprotkb:YOR206W(locus name)|uniprotkb:NOC2(gene name)|psi-mi:NOC2(display_short) psi-mi:brx1_yeast(display_long)|uniprotkb:YOL077C(locus name)|uniprotkb:BRX1(gene name)|psi-mi:BRX1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331195|imex:IM-14275-1570 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014849.3|sgd:S000005732|dip:DIP-4559N|mint:P39744|ensemblfungi:YOR206W(gene)|ensemblfungi:YOR206W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR005343(Protein of unknown function UPF0120) refseq:NP_014565.2|sgd:S000005437|dip:DIP-6317N|mint:Q08235|ensemblfungi:YOL077C(gene)|ensemblfungi:YOL077C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000464"("endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000465"("exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR007109(Brix)|interpro:IPR026532|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5 psi-mi:"MI:0469"(intact) crc64:48C3B9AE076B9B8F crc64:31466853EF0E7301 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:d5I8KJOSG63bZ/Pt+XvKdy/SWws559292 rogid:mPR6HWKwM6RNCRE/vezsYlCmEGY559292 intact-crc:959D1F6C8D9A7A6D|rigid:tu+I99lQ+5Q538ZnAAY+sqYggRQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40094 uniprotkb:P39904 intact:EBI-16605|ensemblfungi:YER157W|uniprotkb:D3DM64 intact:EBI-16418|uniprotkb:Q03379|ensemblfungi:YDR484W|uniprotkb:D6VTA7 psi-mi:cog3_yeast(display_long)|uniprotkb:COG3(gene name)|psi-mi:COG3(display_short)|uniprotkb:GRD20(gene name synonym)|uniprotkb:SEC34(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 3(gene name synonym)|uniprotkb:Protein SEC34(gene name synonym)|uniprotkb:YER157W(locus name) psi-mi:vps52_yeast(display_long)|uniprotkb:VPS52(gene name)|psi-mi:VPS52(display_short)|uniprotkb:YDR484W(locus name)|uniprotkb:D8035.27(orf name)|uniprotkb:SAC2(gene name synonym)|uniprotkb:Suppressor of actin mutation protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331206|imex:IM-14275-1571 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER157W(gene)|ensemblfungi:YER157W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR007265(Sec34-like protein)|refseq:NP_011084.1|sgd:S000000959|dip:DIP-4728N|mint:P40094 go:"GO:0090156"(cellular sphingolipid homeostasis)|interpro:IPR007258(Vps52/Sac2)|ensemblfungi:YDR484W(gene)|ensemblfungi:YDR484W_mRNA(transcript)|go:"GO:0000938"(GARP complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030029"(actin filament-based process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|refseq:NP_010772.1|sgd:S000002892|dip:DIP-3967N|mint:P39904 psi-mi:"MI:0469"(intact) crc64:C7AFBE99010FE571 crc64:F2BF669A72A712C1 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R2r0ZW+nxrykdTHq1cJy9zOmvHo559292 rogid:rP85+ORjSwj4Ar24ZXjolXQCK98559292 intact-crc:298DC770366F039B|rigid:JSYh+FWN3kD5gIoTk2Zo1WBwI5I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39929 uniprotkb:P36095 intact:EBI-17554|uniprotkb:D6VY27|ensemblfungi:YLR025W|uniprotkb:E9P8V6 intact:EBI-26653|uniprotkb:D6VXP5|ensemblfungi:YKL041W psi-mi:snf7_yeast(display_long)|uniprotkb:SNF7(gene name)|psi-mi:SNF7(display_short)|uniprotkb:VPS32(gene name synonym)|uniprotkb:YLR025W(locus name)|uniprotkb:DID1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 32(gene name synonym)|uniprotkb:DOA4-independent degradation protein 1(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 7(gene name synonym) psi-mi:vps24_yeast(display_long)|uniprotkb:YKL041W(locus name)|uniprotkb:YKL254(orf name)|uniprotkb:VPS24(gene name)|psi-mi:VPS24(display_short)|uniprotkb:DID3(gene name synonym)|uniprotkb:DOA4-independent degradation protein 3(gene name synonym)|uniprotkb:ESCRT-III complex subunit VPS24(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331217|imex:IM-14275-1572 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013125.1|sgd:S000004015|ensemblfungi:YLR025W(gene)|ensemblfungi:YLR025W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0071454"(cellular response to anoxia)|go:"GO:1904669"(ATP export)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|rcsb pdb:5FD7|rcsb pdb:5FD9|rcsb pdb:5T8L|rcsb pdb:5T8N|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1747N|mint:P39929 refseq:NP_012883.1|sgd:S000001524|mint:P36095|dip:DIP-7295N|ensemblfungi:YKL041W(gene)|ensemblfungi:YKL041W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR005024(Snf7)|rcsb pdb:6ZH3|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328 psi-mi:"MI:0469"(intact) crc64:5241A18BB181F0C1 crc64:6073C1B680D58E98 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I8qBtNlqTjxLX1HginTOzM3o9oA559292 rogid:mA7XIOAPTcq8iFqDtd5Uk4cdhD0559292 intact-crc:ED269BCDCFA0317F|rigid:d3rbAX8zcSe5biKUsfTOQVbeHj8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39929 uniprotkb:P36108 intact:EBI-17554|uniprotkb:D6VY27|ensemblfungi:YLR025W|uniprotkb:E9P8V6 intact:EBI-26574|uniprotkb:D6VXT5|ensemblfungi:YKL002W psi-mi:snf7_yeast(display_long)|uniprotkb:SNF7(gene name)|psi-mi:SNF7(display_short)|uniprotkb:VPS32(gene name synonym)|uniprotkb:YLR025W(locus name)|uniprotkb:DID1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 32(gene name synonym)|uniprotkb:DOA4-independent degradation protein 1(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 7(gene name synonym) psi-mi:did4_yeast(display_long)|uniprotkb:VPL2(gene name synonym)|uniprotkb:VPS2(gene name synonym)|uniprotkb:VPT14(gene name synonym)|uniprotkb:YKL002W(locus name)|uniprotkb:DID4(gene name)|psi-mi:DID4(display_short)|uniprotkb:CHM2(gene name synonym)|uniprotkb:GRD7(gene name synonym)|uniprotkb:REN1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 2(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 14(gene name synonym)|uniprotkb:ESCRT-III complex subunit VPS2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331228|imex:IM-14275-1573 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013125.1|sgd:S000004015|ensemblfungi:YLR025W(gene)|ensemblfungi:YLR025W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0071454"(cellular response to anoxia)|go:"GO:1904669"(ATP export)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|rcsb pdb:5FD7|rcsb pdb:5FD9|rcsb pdb:5T8L|rcsb pdb:5T8N|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1747N|mint:P39929 refseq:NP_012924.2|sgd:S000001485|mint:P36108|dip:DIP-1916N|ensemblfungi:YKL002W(gene)|ensemblfungi:YKL002W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR005024(Snf7)|rcsb pdb:2V6X|rcsb pdb:6AP1|rcsb pdb:6BMF|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328 psi-mi:"MI:0469"(intact) crc64:5241A18BB181F0C1 crc64:200D07DB4C45DCBC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I8qBtNlqTjxLX1HginTOzM3o9oA559292 rogid:iQ8lcGhal3Pt46dwcOkIW2fp/G0559292 intact-crc:5AA0FAFE4DA10206|rigid:ARVmLKQtRd3YUBo6cMlUxg8D4I4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39929 uniprotkb:P39929 intact:EBI-17554|uniprotkb:D6VY27|ensemblfungi:YLR025W|uniprotkb:E9P8V6 intact:EBI-17554|uniprotkb:D6VY27|ensemblfungi:YLR025W|uniprotkb:E9P8V6 psi-mi:snf7_yeast(display_long)|uniprotkb:SNF7(gene name)|psi-mi:SNF7(display_short)|uniprotkb:VPS32(gene name synonym)|uniprotkb:YLR025W(locus name)|uniprotkb:DID1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 32(gene name synonym)|uniprotkb:DOA4-independent degradation protein 1(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 7(gene name synonym) psi-mi:snf7_yeast(display_long)|uniprotkb:SNF7(gene name)|psi-mi:SNF7(display_short)|uniprotkb:VPS32(gene name synonym)|uniprotkb:YLR025W(locus name)|uniprotkb:DID1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 32(gene name synonym)|uniprotkb:DOA4-independent degradation protein 1(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 7(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331239|imex:IM-14275-1574 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013125.1|sgd:S000004015|ensemblfungi:YLR025W(gene)|ensemblfungi:YLR025W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0071454"(cellular response to anoxia)|go:"GO:1904669"(ATP export)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|rcsb pdb:5FD7|rcsb pdb:5FD9|rcsb pdb:5T8L|rcsb pdb:5T8N|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1747N|mint:P39929 refseq:NP_013125.1|sgd:S000004015|ensemblfungi:YLR025W(gene)|ensemblfungi:YLR025W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0071454"(cellular response to anoxia)|go:"GO:1904669"(ATP export)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|rcsb pdb:5FD7|rcsb pdb:5FD9|rcsb pdb:5T8L|rcsb pdb:5T8N|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1747N|mint:P39929 psi-mi:"MI:0469"(intact) crc64:5241A18BB181F0C1 crc64:5241A18BB181F0C1 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I8qBtNlqTjxLX1HginTOzM3o9oA559292 rogid:I8qBtNlqTjxLX1HginTOzM3o9oA559292 intact-crc:5DD7FFEDE7EA8CEF|rigid:CuP2MR5p8lfZPJWeY83YiHHsYGM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P69771 uniprotkb:P39929 intact:EBI-2053489|uniprotkb:D6VX98|ensemblfungi:YKR035W-A intact:EBI-17554|uniprotkb:D6VY27|ensemblfungi:YLR025W|uniprotkb:E9P8V6 psi-mi:did2_yeast(display_long)|uniprotkb:CHM1(gene name synonym)|uniprotkb:FTI1(gene name synonym)|uniprotkb:Fifty two inhibitor 1(gene name synonym)|uniprotkb:YKR035W-A(locus name)|uniprotkb:VPS46(gene name synonym)|uniprotkb:Charged multivesicular body protein 1(gene name synonym)|uniprotkb:DOA4-independent degradation protein 2(gene name synonym)|uniprotkb:DID2(gene name)|psi-mi:DID2(display_short) psi-mi:snf7_yeast(display_long)|uniprotkb:SNF7(gene name)|psi-mi:SNF7(display_short)|uniprotkb:VPS32(gene name synonym)|uniprotkb:YLR025W(locus name)|uniprotkb:DID1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 32(gene name synonym)|uniprotkb:DOA4-independent degradation protein 1(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 7(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331250|imex:IM-14275-1575 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006435|refseq:NP_012961.3|dip:DIP-52223N|mint:P69771|ensemblfungi:YKR035W-A(gene)|ensemblfungi:YKR035W-A_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|rcsb pdb:3GGZ|rcsb pdb:5H7P refseq:NP_013125.1|sgd:S000004015|ensemblfungi:YLR025W(gene)|ensemblfungi:YLR025W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0071454"(cellular response to anoxia)|go:"GO:1904669"(ATP export)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|rcsb pdb:5FD7|rcsb pdb:5FD9|rcsb pdb:5T8L|rcsb pdb:5T8N|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1747N|mint:P39929 psi-mi:"MI:0469"(intact) crc64:70D1CF4588A8C6E6 crc64:5241A18BB181F0C1 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SVI1+8lRI6qwD0CSLY11Xq0LG0o559292 rogid:I8qBtNlqTjxLX1HginTOzM3o9oA559292 intact-crc:6B0285B134428F4A|rigid:/9MgoWCRMe1bTvMXCfrstizhNXU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39929 uniprotkb:Q03390 intact:EBI-17554|uniprotkb:D6VY27|ensemblfungi:YLR025W|uniprotkb:E9P8V6 intact:EBI-2090142|uniprotkb:D6VTA9|ensemblfungi:YDR486C psi-mi:snf7_yeast(display_long)|uniprotkb:SNF7(gene name)|psi-mi:SNF7(display_short)|uniprotkb:VPS32(gene name synonym)|uniprotkb:YLR025W(locus name)|uniprotkb:DID1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 32(gene name synonym)|uniprotkb:DOA4-independent degradation protein 1(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 7(gene name synonym) psi-mi:vps60_yeast(display_long)|uniprotkb:Charged multivesicular body protein 5(gene name synonym)|uniprotkb:YDR486C(locus name)|uniprotkb:CHM5(gene name synonym)|uniprotkb:MOS10(gene name synonym)|uniprotkb:VPS60(gene name)|psi-mi:VPS60(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331261|imex:IM-14275-1576 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013125.1|sgd:S000004015|ensemblfungi:YLR025W(gene)|ensemblfungi:YLR025W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0071454"(cellular response to anoxia)|go:"GO:1904669"(ATP export)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|rcsb pdb:5FD7|rcsb pdb:5FD9|rcsb pdb:5T8L|rcsb pdb:5T8N|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1747N|mint:P39929 dip:DIP-8785N|sgd:S000002894|refseq:NP_010774.4|mint:Q03390|ensemblfungi:YDR486C(gene)|ensemblfungi:YDR486C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030447"(filamentous growth)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|interpro:IPR005024(Snf7)|rcsb pdb:2LUH|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328 psi-mi:"MI:0469"(intact) crc64:5241A18BB181F0C1 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I8qBtNlqTjxLX1HginTOzM3o9oA559292 rogid:JJYURVH0yGW+NbEfToN2nhk7vvU559292 intact-crc:31B6EA0AF25B2343|rigid:xEAQf6AvaIdTjAUcHKct0hMU/Dk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06263 uniprotkb:P39929 intact:EBI-37098|uniprotkb:Q07057|uniprotkb:D6VYI5|ensemblfungi:YLR181C intact:EBI-17554|uniprotkb:D6VY27|ensemblfungi:YLR025W|uniprotkb:E9P8V6 psi-mi:vta1_yeast(display_long)|uniprotkb:VTA1(gene name)|psi-mi:VTA1(display_short)|uniprotkb:YLR181C(locus name)|uniprotkb:VPS20-associated protein 1(gene name synonym) psi-mi:snf7_yeast(display_long)|uniprotkb:SNF7(gene name)|psi-mi:SNF7(display_short)|uniprotkb:VPS32(gene name synonym)|uniprotkb:YLR025W(locus name)|uniprotkb:DID1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 32(gene name synonym)|uniprotkb:DOA4-independent degradation protein 1(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 7(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331272|imex:IM-14275-1577 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013282.1|sgd:S000004171|mint:Q06263|dip:DIP-4802N|ensemblfungi:YLR181C(gene)|ensemblfungi:YLR181C_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0006869"(lipid transport)|go:"GO:0015031"(protein transport)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR023175|interpro:IPR039431|interpro:IPR041212|interpro:IPR044538|rcsb pdb:2LUH|rcsb pdb:2RKK|rcsb pdb:2RKL|rcsb pdb:3MHV|rcsb pdb:5H7P|rcsb pdb:5UIE|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6OO2|reactome:R-SCE-917729 refseq:NP_013125.1|sgd:S000004015|ensemblfungi:YLR025W(gene)|ensemblfungi:YLR025W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0071454"(cellular response to anoxia)|go:"GO:1904669"(ATP export)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|rcsb pdb:5FD7|rcsb pdb:5FD9|rcsb pdb:5T8L|rcsb pdb:5T8N|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1747N|mint:P39929 psi-mi:"MI:0469"(intact) crc64:BB6E6975596C1674 crc64:5241A18BB181F0C1 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:X9sRQb1nZECFkdjvDUTjxEgokRM559292 rogid:I8qBtNlqTjxLX1HginTOzM3o9oA559292 intact-crc:630D5B9009903591|rigid:oosZFlDHp/fKxKCQMjcRanIcHVs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39936 uniprotkb:P06634 intact:EBI-9006|ensemblfungi:YGL049C|uniprotkb:D6VU91 intact:EBI-5744|uniprotkb:D6W2R0|ensemblfungi:YOR204W psi-mi:if4f2_yeast(display_long)|uniprotkb:YGL049C(locus name)|uniprotkb:TIF4632(gene name)|psi-mi:TIF4632(display_short)|uniprotkb:eIF4G2(gene name synonym)|uniprotkb:mRNA cap-binding protein complex subunit p130(gene name synonym) psi-mi:ded1_yeast(display_long)|uniprotkb:DED1(gene name)|psi-mi:DED1(display_short)|uniprotkb:SPP81(gene name synonym)|uniprotkb:YOR204W(locus name)|uniprotkb:DEAD box protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331283|imex:IM-14275-1578 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036211|reactome:R-SCE-156827|reactome:R-SCE-166208|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-72662|reactome:R-SCE-72702|reactome:R-SCE-975956|reactome:R-SCE-975957|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0034063"(stress granule assembly)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|go:"GO:1902280"(regulation of RNA helicase activity)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022745|ensemblfungi:YGL049C(gene)|ensemblfungi:YGL049C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|refseq:NP_011466.1|sgd:S000003017|mint:P39936|dip:DIP-330N sgd:S000005730|refseq:NP_014847.3|dip:DIP-5820N|mint:P06634|ensemblfungi:YOR204W(gene)|ensemblfungi:YOR204W_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) crc64:BF5E9805CD47908E crc64:B6722D94C03BFA4B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:T8feENVEclKiN5joAyBJ2trBE0A559292 rogid:FkldumX6m5gBuuaG09aTJ0kuMZM559292 intact-crc:CDF10F300D198480|rigid:AsoBbgo2WOrV+fhE1oq3B5gK7zI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39936 uniprotkb:P32588 intact:EBI-9006|ensemblfungi:YGL049C|uniprotkb:D6VU91 intact:EBI-14231|ensemblfungi:YNL016W|uniprotkb:D6W1G2 psi-mi:if4f2_yeast(display_long)|uniprotkb:YGL049C(locus name)|uniprotkb:TIF4632(gene name)|psi-mi:TIF4632(display_short)|uniprotkb:eIF4G2(gene name synonym)|uniprotkb:mRNA cap-binding protein complex subunit p130(gene name synonym) psi-mi:pub1_yeast(display_long)|uniprotkb:ARS consensus-binding protein ACBP-60(gene name synonym)|uniprotkb:Poly uridylate-binding protein(gene name synonym)|uniprotkb:PUB1(gene name)|psi-mi:PUB1(display_short)|uniprotkb:RNP1(gene name synonym)|uniprotkb:YNL016W(locus name)|uniprotkb:N2842(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331294|imex:IM-14275-1579 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036211|reactome:R-SCE-156827|reactome:R-SCE-166208|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-72662|reactome:R-SCE-72702|reactome:R-SCE-975956|reactome:R-SCE-975957|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0034063"(stress granule assembly)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|go:"GO:1902280"(regulation of RNA helicase activity)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022745|ensemblfungi:YGL049C(gene)|ensemblfungi:YGL049C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|refseq:NP_011466.1|sgd:S000003017|mint:P39936|dip:DIP-330N refseq:NP_014382.1|sgd:S000004961|ensemblfungi:YNL016W(gene)|ensemblfungi:YNL016W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043488"(regulation of mRNA stability)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034509|interpro:IPR034639|interpro:IPR035979|rcsb pdb:2LA4|rcsb pdb:3MD1|rcsb pdb:3MD3|rcsb pdb:6Z29|mint:P32588|dip:DIP-5480N psi-mi:"MI:0469"(intact) crc64:BF5E9805CD47908E crc64:3B81A7735505D3CA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:T8feENVEclKiN5joAyBJ2trBE0A559292 rogid:8xFMuEva7leVYDKg3WOmvPtRTFk559292 intact-crc:BF5612B29812B480|rigid:A8y9KnZEbuncgt8kVbBFyy8kfCI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39936 uniprotkb:Q04839 intact:EBI-9006|ensemblfungi:YGL049C|uniprotkb:D6VU91 intact:EBI-27549|uniprotkb:D6W081|ensemblfungi:YMR255W psi-mi:if4f2_yeast(display_long)|uniprotkb:YGL049C(locus name)|uniprotkb:TIF4632(gene name)|psi-mi:TIF4632(display_short)|uniprotkb:eIF4G2(gene name synonym)|uniprotkb:mRNA cap-binding protein complex subunit p130(gene name synonym) psi-mi:gfd1_yeast(display_long)|uniprotkb:GFD1(gene name)|psi-mi:GFD1(display_short)|uniprotkb:YMR255W(locus name)|uniprotkb:YM9920.09(orf name)|uniprotkb:Good for full DBP5 activity protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331305|imex:IM-14275-1580 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036211|reactome:R-SCE-156827|reactome:R-SCE-166208|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-72662|reactome:R-SCE-72702|reactome:R-SCE-975956|reactome:R-SCE-975957|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0034063"(stress granule assembly)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|go:"GO:1902280"(regulation of RNA helicase activity)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022745|ensemblfungi:YGL049C(gene)|ensemblfungi:YGL049C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|refseq:NP_011466.1|sgd:S000003017|mint:P39936|dip:DIP-330N sgd:S000004868|refseq:NP_013982.1|dip:DIP-1254N|mint:Q04839|ensemblfungi:YMR255W(gene)|ensemblfungi:YMR255W_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015031"(protein transport)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:3LCN psi-mi:"MI:0469"(intact) crc64:BF5E9805CD47908E - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:T8feENVEclKiN5joAyBJ2trBE0A559292 rogid:2IqMWMpym7QObadY7Qq00tunNHs559292 intact-crc:8EA1A9F5331E04FF|rigid:/ohb9tut0WG3vRuNGc7dN62kel4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39996 uniprotkb:P39996 intact:EBI-22308|uniprotkb:D3DLN3|ensemblfungi:YEL017W intact:EBI-22308|uniprotkb:D3DLN3|ensemblfungi:YEL017W psi-mi:gtt3_yeast(display_long)|uniprotkb:GTT3(gene name)|psi-mi:GTT3(display_short)|uniprotkb:YEL017W(locus name) psi-mi:gtt3_yeast(display_long)|uniprotkb:GTT3(gene name)|psi-mi:GTT3(display_short)|uniprotkb:YEL017W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331316|imex:IM-14275-1581 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000743|refseq:NP_010899.3|dip:DIP-2062N|mint:P39996|ensemblfungi:YEL017W(gene)|ensemblfungi:YEL017W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR038872 sgd:S000000743|refseq:NP_010899.3|dip:DIP-2062N|mint:P39996|ensemblfungi:YEL017W(gene)|ensemblfungi:YEL017W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR038872 psi-mi:"MI:0469"(intact) crc64:E9F07EFD2A522006 crc64:E9F07EFD2A522006 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YxznRNPatBf8VkhVPwSCfB5pCDU559292 rogid:YxznRNPatBf8VkhVPwSCfB5pCDU559292 intact-crc:D28694509B481642|rigid:u2iuV2dVvlbTQnv8KVVEK5h773k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08235 uniprotkb:P40007 intact:EBI-3775|uniprotkb:D6W1Z1|ensemblfungi:YOL077C intact:EBI-22439|uniprotkb:D3DLP8|ensemblfungi:YER002W psi-mi:brx1_yeast(display_long)|uniprotkb:YOL077C(locus name)|uniprotkb:BRX1(gene name)|psi-mi:BRX1(display_short) psi-mi:nop16_yeast(display_long)|uniprotkb:NOP16(gene name)|psi-mi:NOP16(display_short)|uniprotkb:YER002W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331327|imex:IM-14275-1582 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014565.2|sgd:S000005437|dip:DIP-6317N|mint:Q08235|ensemblfungi:YOL077C(gene)|ensemblfungi:YOL077C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000464"("endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000465"("exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR007109(Brix)|interpro:IPR026532|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5 refseq:NP_010917.3|sgd:S000000804|dip:DIP-6555N|mint:P40007|ensemblfungi:YER002W(gene)|ensemblfungi:YER002W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR019002|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5 psi-mi:"MI:0469"(intact) crc64:31466853EF0E7301 crc64:B1D27F0B817AADED figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mPR6HWKwM6RNCRE/vezsYlCmEGY559292 rogid:PD98kIVFrhy3yk5bcTAz5DxIDaA559292 intact-crc:FFAA27E47FFA27EF|rigid:gDNXIuvmCXdGU1Ed5KDN1vaTzQc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53188 uniprotkb:P40010 intact:EBI-23731|uniprotkb:D6VUA9|ensemblfungi:YGL029W intact:EBI-22449|uniprotkb:D3DLQ2|ensemblfungi:YER006W psi-mi:cgr1_yeast(display_long)|uniprotkb:YGL029W(locus name)|uniprotkb:CGR1(gene name)|psi-mi:CGR1(display_short)|uniprotkb:Coiled-coil growth-regulated protein 1(gene name synonym) psi-mi:nug1_yeast(display_long)|uniprotkb:YER006W(locus name)|uniprotkb:NUG1(gene name)|psi-mi:NUG1(display_short)|uniprotkb:Nuclear GTPase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331338|imex:IM-14275-1583 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011486.1|sgd:S000002997|dip:DIP-5450N|mint:P53188|ensemblfungi:YGL029W(gene)|ensemblfungi:YGL029W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR005579(Cgr1)|rcsb pdb:3JCT|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6YLG|rcsb pdb:6YLH refseq:NP_010921.1|sgd:S000000808|dip:DIP-6291N|mint:P40010|ensemblfungi:YER006W(gene)|ensemblfungi:YER006W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0015031"(protein transport)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR006073(GTP1/OBG)|interpro:IPR014813(GNL3L/Grn1 putative GTPase)|interpro:IPR023179|interpro:IPR027417|interpro:IPR030378|rcsb pdb:3JCT|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6YLG|rcsb pdb:6YLH|rcsb pdb:6YLX|rcsb pdb:6YLY|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) - crc64:F75E4860D114756A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:G7SUf9/XRWXFaYG1LRPoChi6BVA559292 rogid:tbCcXPtanWAfDrM2HMfCH1vb93c559292 intact-crc:8B4C1D2DE1C157E1|rigid:qxmhRYWJeCWFou6MY1SKb6FRUFc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40013 uniprotkb:Q8TGU5 intact:EBI-3614|uniprotkb:D3DLR4|ensemblfungi:YER016W intact:EBI-2042814|uniprotkb:D6VQU1|ensemblfungi:YBR296C-A psi-mi:bim1_yeast(display_long)|uniprotkb:BIM1(gene name)|psi-mi:BIM1(display_short)|uniprotkb:YER016W(locus name) psi-mi:yb296_yeast(display_long)|uniprotkb:YBR296C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331349|imex:IM-14275-1584 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010932.1|sgd:S000000818|dip:DIP-1295N|mint:P40013|ensemblfungi:YER016W(gene)|ensemblfungi:YER016W_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0030543"(2-micrometer plasmid partitioning)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:1904825"(protein localization to microtubule plus-end)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR036133|interpro:IPR036872|rcsb pdb:2QJX|rcsb pdb:4E61|rcsb pdb:6FC6 sgd:S000028605|refseq:NP_878055.3|mint:Q8TGU5|ensemblfungi:YBR296C-A(gene)|ensemblfungi:YBR296C-A_mRNA(transcript)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity) psi-mi:"MI:0469"(intact) crc64:C9087CB46A32BD74 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UdSYdsJZ9fLO9XjYqOYoK1TzlDE559292 rogid:DZubWD7lnwtea4Ne/bK1ITPFaJk559292 intact-crc:341BD60D1C21F8AC|rigid:gyawu9NC0QQN/6x0Kub12TNTfnE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40018 uniprotkb:P38757 intact:EBI-432|uniprotkb:D3DLS8|ensemblfungi:YER029C intact:EBI-24435|uniprotkb:D3DKU7|ensemblfungi:YHR004C psi-mi:rsmb_yeast(display_long)|uniprotkb:SMB1(gene name)|psi-mi:SMB1(display_short)|uniprotkb:Sm protein B(gene name synonym)|uniprotkb:YER029C(locus name) psi-mi:nem1_yeast(display_long)|uniprotkb:NEM1(gene name)|psi-mi:NEM1(display_short)|uniprotkb:YHR004C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331360|imex:IM-14275-1585 author score:99.32 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000831|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|ensemblfungi:YER029C(gene)|ensemblfungi:YER029C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|refseq:NP_010946.3|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|dip:DIP-843N|mint:P40018 refseq:NP_011867.1|sgd:S000001046|dip:DIP-2440N|mint:P38757|go:"GO:0071071"(regulation of phospholipid biosynthetic process)|go:"GO:0071072"(negative regulation of phospholipid biosynthetic process)|go:"GO:0071595"(Nem1-Spo7 phosphatase complex)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0140042"(lipid droplet formation)|go:"GO:1903740"(positive regulation of phosphatidate phosphatase activity)|interpro:IPR004274(NLI interacting factor)|interpro:IPR011948(Dullard-like phosphatase domain)|interpro:IPR023214|interpro:IPR036412|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|ensemblfungi:YHR004C(gene)|ensemblfungi:YHR004C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034613"(cellular protein localization) psi-mi:"MI:0469"(intact) crc64:0A1078D5AA241430 crc64:4260748606E17062 figure legend:tables S3 and S4|author-confidence:99.32|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:b62+dBOdvQgeE0oup4kbXbviS1U559292 rogid:/MOMTh4/2a448OwmUgC+a2qY+no559292 intact-crc:EC9D430470A24948|rigid:fJSziTTbhtTAFLADHSALeLGjQAQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39517 uniprotkb:P40023 intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C intact:EBI-22493|uniprotkb:D3DLT4|ensemblfungi:YER035W psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:edc2_yeast(display_long)|uniprotkb:YER035W(locus name)|uniprotkb:EDC2(gene name)|psi-mi:EDC2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331371|imex:IM-14275-1586 author score:83.40 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 sgd:S000000837|refseq:NP_010952.3|dip:DIP-5234N|mint:P40023|ensemblfungi:YER035W(gene)|ensemblfungi:YER035W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0032056"(positive regulation of translation in response to stress) psi-mi:"MI:0469"(intact) crc64:062CFA56DF6F2CEE crc64:4D8A461EFD78BFA9 figure legend:tables S3 and S4|author-confidence:83.40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 rogid:nW5oKJQ2vCy2/EmFSke5vZAK/3U559292 intact-crc:EFD98533476F6DDF|rigid:dT9IoY6ZoKj5DAzanBoQOEDEXyE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40023 uniprotkb:Q12517 intact:EBI-22493|uniprotkb:D3DLT4|ensemblfungi:YER035W intact:EBI-38519|uniprotkb:D6W1S0|ensemblfungi:YOL149W psi-mi:edc2_yeast(display_long)|uniprotkb:YER035W(locus name)|uniprotkb:EDC2(gene name)|psi-mi:EDC2(display_short) psi-mi:dcp1_yeast(display_long)|uniprotkb:DCP1(gene name)|psi-mi:DCP1(display_short)|uniprotkb:YOL149W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331382|imex:IM-14275-1587 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000837|refseq:NP_010952.3|dip:DIP-5234N|mint:P40023|ensemblfungi:YER035W(gene)|ensemblfungi:YER035W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0032056"(positive regulation of translation in response to stress) refseq:NP_014492.1|sgd:S000005509|mint:Q12517|dip:DIP-1288N|ensemblfungi:YOL149W(gene)|ensemblfungi:YOL149W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0098745"(Dcp1-Dcp2 complex)|interpro:IPR010334(Dcp1-like decapping)|rcsb pdb:1Q67|rcsb pdb:6Y3Z|reactome:R-SCE-430039|reactome:R-SCE-450385|reactome:R-SCE-450513 psi-mi:"MI:0469"(intact) crc64:4D8A461EFD78BFA9 crc64:8456B1C96C121C4D figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nW5oKJQ2vCy2/EmFSke5vZAK/3U559292 rogid:CXLHokbNWY54t80lw79Or4Wmb1g559292 intact-crc:D77F3C5058E16E4D|rigid:6UgPDcnqtpOjZypQQYMZeIowHOU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27895 uniprotkb:P40029 intact:EBI-4687|uniprotkb:D3DLI9|ensemblfungi:YEL061C intact:EBI-11441|ensemblfungi:YER042W|uniprotkb:D3DLU2 psi-mi:cin8_yeast(display_long)|uniprotkb:CIN8(gene name)|psi-mi:CIN8(display_short)|uniprotkb:KSL2(gene name synonym)|uniprotkb:YEL061C(locus name)|uniprotkb:Chromosome instability protein 8(gene name synonym) psi-mi:msra_yeast(display_long)|uniprotkb:MXR1(gene name)|psi-mi:MXR1(display_short)|uniprotkb:Protein-methionine-S-oxide reductase(gene name synonym)|uniprotkb:"Peptide-methionine (S)-S-oxide reductase"(gene name synonym)|uniprotkb:YER042W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331393|imex:IM-14275-1588 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010853.2|sgd:S000000787|dip:DIP-3004N|mint:P27895|ensemblfungi:YEL061C(gene)|ensemblfungi:YEL061C_mRNA(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000073"(initial mitotic spindle pole body separation)|go:"GO:0000235"(astral microtubule)|go:"GO:0000776"(kinetochore)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0033047"(regulation of mitotic sister chromatid segregation)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|reactome:R-SCE-983189 ensemblfungi:YER042W(gene)|ensemblfungi:YER042W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008113"("peptide-methionine (S)-S-oxide reductase activity")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036456"("L-methionine-(S)-S-oxide reductase activity")|rcsb pdb:3PIL|rcsb pdb:3PIM|rcsb pdb:3PIN|refseq:NP_010960.1|sgd:S000000844|interpro:IPR002569(Methionine sulphoxide reductase A)|interpro:IPR036509|mint:P40029 psi-mi:"MI:0469"(intact) crc64:B33141C45748CE67 - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:EeAE7ctjQtgTg2WBss2PMZ4qV8E559292 rogid:qa4BOix8taLsa3wYUJp340iVeGs559292 intact-crc:EA0EC5F613EFF2A4|rigid:G2ZNtYF6hJC9zW8dAk/Ke5+Rlr4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40037 uniprotkb:P47006 intact:EBI-8389|uniprotkb:D3DLW1|ensemblfungi:YER057C intact:EBI-26109|uniprotkb:D6VW37|ensemblfungi:YJL148W psi-mi:hmf1_yeast(display_long)|uniprotkb:HMF1(gene name)|psi-mi:HMF1(display_short)|uniprotkb:HIG1(gene name synonym)|uniprotkb:High dosage growth inhibitor(gene name synonym)|uniprotkb:Homologous mitochondrial matrix factor 1(gene name synonym)|uniprotkb:YER057C(locus name) psi-mi:rpa34_yeast(display_long)|uniprotkb:YJL148W(locus name)|uniprotkb:J0637(orf name)|uniprotkb:RPA34(gene name)|psi-mi:RPA34(display_short)|uniprotkb:DNA-directed DNA-dependent RNA polymerase 34.5 kDa polypeptide(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331404|imex:IM-14275-1589 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000859|refseq:NP_010978.3|dip:DIP-4314N|mint:P40037|ensemblfungi:YER057C(gene)|ensemblfungi:YER057C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0019239"(deaminase activity)|go:"GO:1901565"(organonitrogen compound catabolic process)|interpro:IPR006056(YjgF-like protein)|interpro:IPR006175(Endoribonuclease L-PSP)|interpro:IPR019897|interpro:IPR035959|rcsb pdb:1JD1 refseq:NP_012387.1|sgd:S000003684|mint:P47006|dip:DIP-7973N|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|ensemblfungi:YJL148W(gene)|ensemblfungi:YJL148W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR013240(RNA polymerase I, subunit RPA34.5, fungi)|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61 psi-mi:"MI:0469"(intact) crc64:D1D252BBA47F81E8 crc64:DCD42DFEC574EDB6 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XCScAuZc5h+pEgQlI2obiHQ+0w4559292 rogid:KCG3Ws8+82TSLsqPB7bedHq/JEI559292 intact-crc:946E1318A8D04EF5|rigid:c4ghxGhDic2NgKVdgp1Avk+4iEQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24783 uniprotkb:P40040 intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W intact:EBI-19254|uniprotkb:D3DLW8|ensemblfungi:YER063W psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:tho1_yeast(display_long)|uniprotkb:YER063W(locus name)|uniprotkb:THO1(gene name)|psi-mi:THO1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331415|imex:IM-14275-1590 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 refseq:NP_010985.1|sgd:S000000865|ensemblfungi:YER063W(gene)|ensemblfungi:YER063W_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0022618"(ribonucleoprotein complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR036361|interpro:IPR040746|rcsb pdb:1H1J|rcsb pdb:2WQG|rcsb pdb:4UZW|rcsb pdb:4UZX|dip:DIP-3983N|mint:P40040 psi-mi:"MI:0469"(intact) crc64:30FE3D4C7E653120 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 rogid:eP5eukamLvSYux9zzcnLzLq7nPY559292 intact-crc:BF2B1DB346F79BE1|rigid:fxh0F6jKHTfJqoAnhfqP1O57eCs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40040 uniprotkb:P40040 intact:EBI-19254|uniprotkb:D3DLW8|ensemblfungi:YER063W intact:EBI-19254|uniprotkb:D3DLW8|ensemblfungi:YER063W psi-mi:tho1_yeast(display_long)|uniprotkb:YER063W(locus name)|uniprotkb:THO1(gene name)|psi-mi:THO1(display_short) psi-mi:tho1_yeast(display_long)|uniprotkb:YER063W(locus name)|uniprotkb:THO1(gene name)|psi-mi:THO1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331426|imex:IM-14275-1591 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010985.1|sgd:S000000865|ensemblfungi:YER063W(gene)|ensemblfungi:YER063W_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0022618"(ribonucleoprotein complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR036361|interpro:IPR040746|rcsb pdb:1H1J|rcsb pdb:2WQG|rcsb pdb:4UZW|rcsb pdb:4UZX|dip:DIP-3983N|mint:P40040 refseq:NP_010985.1|sgd:S000000865|ensemblfungi:YER063W(gene)|ensemblfungi:YER063W_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0022618"(ribonucleoprotein complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR036361|interpro:IPR040746|rcsb pdb:1H1J|rcsb pdb:2WQG|rcsb pdb:4UZW|rcsb pdb:4UZX|dip:DIP-3983N|mint:P40040 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:eP5eukamLvSYux9zzcnLzLq7nPY559292 rogid:eP5eukamLvSYux9zzcnLzLq7nPY559292 intact-crc:C59D7B61EE110D88|rigid:9ULPD1ObCYFcTQhwKQqVL+7KSno false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33750 uniprotkb:P40055 intact:EBI-17651|uniprotkb:D6VXZ1|ensemblfungi:YLL011W intact:EBI-22597|uniprotkb:D3DLY9|ensemblfungi:YER082C psi-mi:dca13_yeast(display_long)|uniprotkb:SOF1(gene name)|psi-mi:SOF1(display_short)|uniprotkb:YLL011W(locus name)|uniprotkb:L1339(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein SOF1(gene name synonym) psi-mi:utp7_yeast(display_long)|uniprotkb:UTP7(gene name)|psi-mi:UTP7(display_short)|uniprotkb:KRE31(gene name synonym)|uniprotkb:U three protein 7(gene name synonym)|uniprotkb:YER082C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331437|imex:IM-14275-1592 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLL011W(gene)|ensemblfungi:YLL011W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR007287(Sof1-like protein)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_013090.1|sgd:S000003934|dip:DIP-746N|mint:P33750 refseq:NP_011005.1|sgd:S000000884|dip:DIP-5398N|mint:P40055|ensemblfungi:YER082C(gene)|ensemblfungi:YER082C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0032040"(small-subunit processome)|interpro:IPR001680(WD40 repeat)|interpro:IPR012952(BING4, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR040315|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:4B28371CC61DE7E4 crc64:A254AD9AC1142AA5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:stTLdABNsa3SvTkNOZBteSNAVJA559292 rogid:2uFPq4stCHLw5niaXwAZ/7rXjdQ559292 intact-crc:2B81F1C347DEAC73|rigid:jc6VmmRgd6WIzu6bdOwiC9qidTA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12038 uniprotkb:P40061 intact:EBI-17573|uniprotkb:D6W442|ensemblfungi:YPR032W intact:EBI-22621|uniprotkb:D3DM00|ensemblfungi:YER093C psi-mi:sro7_yeast(display_long)|uniprotkb:SRO7(gene name)|psi-mi:SRO7(display_short)|uniprotkb:SNI1(gene name synonym)|uniprotkb:YPR032W(locus name)|uniprotkb:YP9367.12(orf name)|uniprotkb:SOP1(gene name synonym)|uniprotkb:Suppressor of RHO3 protein 7(gene name synonym)|uniprotkb:Polarity protein SRO7(gene name synonym)|uniprotkb:Sodium protection protein 1(gene name synonym) psi-mi:tsc11_yeast(display_long)|uniprotkb:AVO3(gene name synonym)|uniprotkb:YER093C(locus name)|uniprotkb:TSC11(gene name)|psi-mi:TSC11(display_short)|uniprotkb:Adheres voraciously to TOR2 protein 3(gene name synonym)|uniprotkb:Temperature-sensitive CSG2 suppressor protein 11(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331448|imex:IM-14275-1593 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015357.1|sgd:S000006236|ensemblfungi:YPR032W(gene)|ensemblfungi:YPR032W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045159"(myosin II binding)|go:"GO:0050708"(regulation of protein secretion)|interpro:IPR013905("Lethal giant larvae (Lgl) like, C-terminal")|interpro:IPR036322|rcsb pdb:2OAJ|dip:DIP-2581N|mint:Q12038 refseq:NP_011018.1|sgd:S000000895|dip:DIP-4957N|mint:P40061|ensemblfungi:YER093C(gene)|ensemblfungi:YER093C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028267|interpro:IPR028268|interpro:IPR029451|interpro:IPR029452|interpro:IPR029453|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757 psi-mi:"MI:0469"(intact) crc64:FFB0901883009815 crc64:07BB5D75BA204E50 figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3nYgL2CW3rzKE71MX0MekJKKUlk559292 rogid:VWXhP0KgrXl8YKFmjxSKYVJbMcQ559292 intact-crc:5BB1C5018D7D8B38|rigid:o1Q0W46mQ+6ToMwA77C4og1kUq0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06634 uniprotkb:P40070 intact:EBI-5744|uniprotkb:D6W2R0|ensemblfungi:YOR204W intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W psi-mi:ded1_yeast(display_long)|uniprotkb:DED1(gene name)|psi-mi:DED1(display_short)|uniprotkb:SPP81(gene name synonym)|uniprotkb:YOR204W(locus name)|uniprotkb:DEAD box protein 1(gene name synonym) psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331459|imex:IM-14275-1594 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005730|refseq:NP_014847.3|dip:DIP-5820N|mint:P06634|ensemblfungi:YOR204W(gene)|ensemblfungi:YOR204W_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763|reactome:R-SCE-6798695 sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:B6722D94C03BFA4B crc64:69CAC1F01D5BFA98 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FkldumX6m5gBuuaG09aTJ0kuMZM559292 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 intact-crc:9B08267DF4DDBCAD|rigid:hez2xte12F+HOCP9hqIGRjyy2e4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40070 uniprotkb:P24276 intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W intact:EBI-18153|uniprotkb:D6VSS2|ensemblfungi:YDR293C psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:ssd1_yeast(display_long)|uniprotkb:SSD1(gene name)|psi-mi:SSD1(display_short)|uniprotkb:CLA1(gene name synonym)|uniprotkb:RLD1(gene name synonym)|uniprotkb:SRK1(gene name synonym)|uniprotkb:YDR293C(locus name)|uniprotkb:D9819.4(orf name)|uniprotkb:Protein SRK1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331470|imex:IM-14275-1595 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 refseq:NP_010579.1|sgd:S000002701|ensemblfungi:YDR293C(gene)|ensemblfungi:YDR293C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051301"(cell division)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR041093|interpro:IPR041505|rcsb pdb:5NCL|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007049"(cell cycle)|dip:DIP-6449N|mint:P24276 psi-mi:"MI:0469"(intact) crc64:69CAC1F01D5BFA98 crc64:3D50FD6838ECA514 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 rogid:myt8+lnu2/li6TuGiM5GBfMtUiw559292 intact-crc:1BB781685EC996DD|rigid:0Aukf5uB03dg1xTSZVgBTa1D9fg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40070 uniprotkb:P25339 intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W intact:EBI-23703|uniprotkb:D6VUC3|ensemblfungi:YGL014W psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:puf4_yeast(display_long)|uniprotkb:PUF4(gene name)|psi-mi:PUF4(display_short)|uniprotkb:YGL023(orf name)|uniprotkb:YGL014W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331481|imex:IM-14275-1596 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 refseq:NP_011501.1|sgd:S000002982|dip:DIP-2638N|mint:P25339|ensemblfungi:YGL014W(gene)|ensemblfungi:YGL014W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:3BWT|rcsb pdb:3BX2|rcsb pdb:3BX3|rcsb pdb:4DZS|go:"GO:0003729"(mRNA binding) psi-mi:"MI:0469"(intact) crc64:69CAC1F01D5BFA98 crc64:659BA1062439F642 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 rogid:spjnSzTKOyi8X0oMi4wOTS+72hY559292 intact-crc:9A23BDE39598C2A6|rigid:Nj1ntWBkTD0poS05E6JjJWJmJ4c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40070 uniprotkb:P25567 intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W intact:EBI-18084|uniprotkb:D6VQX8|ensemblfungi:YCL037C psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:sro9_yeast(display_long)|uniprotkb:SRO9(gene name)|psi-mi:SRO9(display_short)|uniprotkb:YCL037C(locus name)|uniprotkb:YCL37C(orf name)|uniprotkb:Suppressor of RHO3 protein 9(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331494|imex:IM-14275-1597 author score:99.24 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 refseq:NP_009893.2|sgd:S000000542|ensemblfungi:YCL037C(gene)|ensemblfungi:YCL037C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|dip:DIP-6638N|mint:P25567 psi-mi:"MI:0469"(intact) crc64:69CAC1F01D5BFA98 crc64:B1B720D40C7B9914 figure legend:tables S3 and S4|author-confidence:99.24|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 rogid:CouwiBsK7S3Tm6CoBsu3LdWfelg559292 intact-crc:80A338BDE71241D6|rigid:mkT2ZiQdme43v7xBw0+nvdGBfeg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40070 uniprotkb:P25644 intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W intact:EBI-204|uniprotkb:Q8NKJ3|uniprotkb:D6VR80|ensemblfungi:YCR077C psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:pat1_yeast(display_long)|uniprotkb:PAT1(gene name)|psi-mi:PAT1(display_short)|uniprotkb:Decapping activator and translational repressor PAT1(gene name synonym)|uniprotkb:mRNA turnover protein 1(gene name synonym)|uniprotkb:MRT1(gene name synonym)|uniprotkb:Topoisomerase II-associated protein PAT1(gene name synonym)|uniprotkb:YCR77C(orf name)|uniprotkb:YCR077C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331505|imex:IM-14275-1598 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 refseq:NP_010002.3|sgd:S000000673|mint:P25644|dip:DIP-883N|ensemblfungi:YCR077C(gene)|ensemblfungi:YCR077C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000776"(kinetochore)|go:"GO:0000932"(P-body)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033962"(P-body assembly)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0051301"(cell division)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR019167|interpro:IPR039900|rcsb pdb:4BRW|rcsb pdb:4C8Q|rcsb pdb:4N0A|rcsb pdb:4OGP|rcsb pdb:4OJJ|rcsb pdb:5LM5|rcsb pdb:5LMF|rcsb pdb:5LMG|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:69CAC1F01D5BFA98 crc64:2DBE1210C173E468 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 rogid:kov8R0RAgIOPffQ7ydjCUxjoE/M559292 intact-crc:BE5658D029EFDDAA|rigid:Ufg6JJa1az9MsweVsYiSNntrNfQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40070 uniprotkb:P25655 intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331516|imex:IM-14275-1599 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 psi-mi:"MI:0469"(intact) crc64:69CAC1F01D5BFA98 crc64:5B2AE15BCF95E009 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 intact-crc:D03758D4902B3C70|rigid:9nAk2dUW3l/LQEXD7QqPjMuBVIs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40070 uniprotkb:P32588 intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W intact:EBI-14231|ensemblfungi:YNL016W|uniprotkb:D6W1G2 psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:pub1_yeast(display_long)|uniprotkb:ARS consensus-binding protein ACBP-60(gene name synonym)|uniprotkb:Poly uridylate-binding protein(gene name synonym)|uniprotkb:PUB1(gene name)|psi-mi:PUB1(display_short)|uniprotkb:RNP1(gene name synonym)|uniprotkb:YNL016W(locus name)|uniprotkb:N2842(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331527|imex:IM-14275-1600 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 refseq:NP_014382.1|sgd:S000004961|ensemblfungi:YNL016W(gene)|ensemblfungi:YNL016W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043488"(regulation of mRNA stability)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034509|interpro:IPR034639|interpro:IPR035979|rcsb pdb:2LA4|rcsb pdb:3MD1|rcsb pdb:3MD3|rcsb pdb:6Z29|mint:P32588|dip:DIP-5480N psi-mi:"MI:0469"(intact) crc64:69CAC1F01D5BFA98 crc64:3B81A7735505D3CA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 rogid:8xFMuEva7leVYDKg3WOmvPtRTFk559292 intact-crc:E9AE892F61D68CAD|rigid:BDhpHS0Jkix3tmNT3BYCY0XnKj0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35732 uniprotkb:P40070 intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331538|imex:IM-14275-1601 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:05734E2D0B7389AC crc64:69CAC1F01D5BFA98 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 intact-crc:3523C724D8CC5D92|rigid:dp2KIhWs/hOl68XCYCbREnG2IEI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39517 uniprotkb:P40070 intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331549|imex:IM-14275-1602 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:062CFA56DF6F2CEE crc64:69CAC1F01D5BFA98 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 intact-crc:FB33C3BE99201A05|rigid:IlWIb3O1MeRyg+gFv+Zlzm5YP8k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40070 uniprotkb:P39998 intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W intact:EBI-22300|uniprotkb:D3DLN5|ensemblfungi:YEL015W psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:edc3_yeast(display_long)|uniprotkb:EDC3(gene name)|psi-mi:EDC3(display_short)|uniprotkb:LSM16(gene name synonym)|uniprotkb:YEL015W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331560|imex:IM-14275-1603 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 refseq:NP_010901.1|sgd:S000000741|dip:DIP-842N|mint:P39998|ensemblfungi:YEL015W(gene)|ensemblfungi:YEL015W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0033962"(P-body assembly)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR019050|interpro:IPR025762|interpro:IPR036652|rcsb pdb:4BRU|rcsb pdb:6Y3Z|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:69CAC1F01D5BFA98 crc64:BF28AE67F9303A73 figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 rogid:6NZRCnakEXzFmlF+UujC024p1GE559292 intact-crc:03FA3B9464ECC333|rigid:qiK0dnjK+iKMbEdlxkwgNG9KJwg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40070 uniprotkb:P40070 intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331571|imex:IM-14275-1604 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:69CAC1F01D5BFA98 crc64:69CAC1F01D5BFA98 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 intact-crc:E7DEB07C89B89BC2|rigid:zRf1z71U1TkcRrGIuigpwqmlKco false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40070 uniprotkb:P45978 intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W intact:EBI-16691|ensemblfungi:YPR129W|uniprotkb:D6W4C6 psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:scd6_yeast(display_long)|uniprotkb:P9659.10(orf name)|uniprotkb:YPR129W(locus name)|uniprotkb:SCD6(gene name)|psi-mi:SCD6(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331582|imex:IM-14275-1605 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 ensemblfungi:YPR129W(gene)|ensemblfungi:YPR129W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:0003729"(mRNA binding)|interpro:IPR025609|refseq:NP_015454.1|sgd:S000006333|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR019050|interpro:IPR025761|interpro:IPR025762|interpro:IPR025768|mint:P45978 psi-mi:"MI:0469"(intact) crc64:69CAC1F01D5BFA98 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 rogid:QRNg1nbLjsxR5twooPvrSPZTWO0559292 intact-crc:DE8F5F1DA92ADD81|rigid:VJJhEN96d0dxb43tfpmpk1sbtic false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53235 uniprotkb:P40070 intact:EBI-23172|uniprotkb:D6VUI9|uniprotkb:Q45U32|ensemblfungi:YGR054W intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W psi-mi:eif2a_yeast(display_long)|uniprotkb:YGR054W(locus name) psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331593|imex:IM-14275-1606 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003286|refseq:NP_011568.3|dip:DIP-5518N|mint:P53235|ensemblfungi:YGR054W(gene)|ensemblfungi:YGR054W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like) sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:F3C2E78504D83418 crc64:69CAC1F01D5BFA98 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:x8zDCH5W5GusC7qYd0mDATXhGVI559292 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 intact-crc:7C71802D21E2471C|rigid:xLCZvrN+NzsfaMRJbf2KMZ9pD0k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40070 uniprotkb:P53550 intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W intact:EBI-270|uniprotkb:B0KZS6|uniprotkb:B0KZU4|uniprotkb:B0KZW2|uniprotkb:B0KZY0|uniprotkb:B0KZY9|uniprotkb:B0KZZ8|uniprotkb:B0L007|uniprotkb:Q6LCS6|uniprotkb:D6W164|ensemblfungi:YNL118C psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:dcp2_yeast(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:Protein PSU1(gene name synonym)|uniprotkb:PSU1(gene name synonym)|uniprotkb:mRNA-decapping enzyme subunit 2(gene name synonym)|uniprotkb:N1917(orf name)|uniprotkb:YNL118C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331604|imex:IM-14275-1607 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 refseq:NP_014281.1|sgd:S000005062|mint:P53550|dip:DIP-969N|ensemblfungi:YNL118C(gene)|ensemblfungi:YNL118C_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0034063"(stress granule assembly)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0098745"(Dcp1-Dcp2 complex)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:2JVB|rcsb pdb:4K6E|rcsb pdb:4KG3|rcsb pdb:4KG4|rcsb pdb:5LM5|rcsb pdb:5LMF|rcsb pdb:5LMG|rcsb pdb:6Y3Z|reactome:R-SCE-430039|reactome:R-SCE-450385|reactome:R-SCE-450513 psi-mi:"MI:0469"(intact) crc64:69CAC1F01D5BFA98 crc64:D53CA2C5A546FA4A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 rogid:ER6Kq15/LioWZN7Rw1kAVESWAss559292 intact-crc:165BAF8676E9A013|rigid:ii7/4SRxQYfxU7tFZFJBt+/8Kgs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40070 uniprotkb:P53829 intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331615|imex:IM-14275-1608 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 psi-mi:"MI:0469"(intact) crc64:69CAC1F01D5BFA98 crc64:F3DBABE6AD3C7F3C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 intact-crc:2A2A0E35F0C95CFC|rigid:/AnLS+CobssE3R1Snp1lXSOuIJw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53849 uniprotkb:P40070 intact:EBI-29244|uniprotkb:D6W0T8|ensemblfungi:YNL255C intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W psi-mi:gis2_yeast(display_long)|uniprotkb:GIS2(gene name)|psi-mi:GIS2(display_short)|uniprotkb:N0852(orf name)|uniprotkb:YNL255C(locus name) psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331626|imex:IM-14275-1609 author score:99.24 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014144.1|sgd:S000005199|dip:DIP-2669N|mint:P53849|ensemblfungi:YNL255C(gene)|ensemblfungi:YNL255C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045182"(translation regulator activity)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875 sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:E72696428F85CA3F crc64:69CAC1F01D5BFA98 figure legend:tables S3 and S4|author-confidence:99.24|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kftHFJVi7QRZASmr4hLdALvleR4559292 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 intact-crc:BDED5B6F24156539|rigid:/NqFxhbEfDnU4Khi8rv20gQuQ4c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P57743 uniprotkb:P40070 intact:EBI-10227|uniprotkb:Q05176|uniprotkb:Q06759|uniprotkb:D6VZ73|ensemblfungi:YLR438C-A intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W psi-mi:lsm3_yeast(display_long)|uniprotkb:LSM3(gene name)|psi-mi:LSM3(display_short)|uniprotkb:SMX4(gene name synonym)|uniprotkb:USS2(gene name synonym)|uniprotkb:YLR438C-A(locus name)|uniprotkb:SmX4 protein(gene name synonym) psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331637|imex:IM-14275-1610 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006434|ensemblfungi:YLR438C-A(gene)|ensemblfungi:YLR438C-A_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034105|interpro:IPR040002|rcsb pdb:3BW1|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:4N0A|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039|rcsb pdb:4M75|refseq:NP_013543.3|dip:DIP-2587N|mint:P57743 sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:787084EF6A5945B7 crc64:69CAC1F01D5BFA98 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nYl7At1SnlSwN+nWr1F1xm0tdDE559292 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 intact-crc:279D728BCCB065CF|rigid:c7t4dWKsbrrQx4jbrLQ544bGrfc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06406 uniprotkb:P40070 intact:EBI-196|uniprotkb:D6VT10|ensemblfungi:YDR378C intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W psi-mi:lsm6_yeast(display_long)|uniprotkb:LSM6(gene name)|psi-mi:LSM6(display_short)|uniprotkb:D9481.18(orf name)|uniprotkb:YDR378C(locus name) psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331648|imex:IM-14275-1611 author score:99.24 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010666.2|sgd:S000002786|mint:Q06406|dip:DIP-1418N|ensemblfungi:YDR378C(gene)|ensemblfungi:YDR378C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0008033"(tRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:74FE40A4509CEF33 crc64:69CAC1F01D5BFA98 figure legend:tables S3 and S4|author-confidence:99.24|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:JQtrhOkngO6APIPCFMRnKogB96c559292 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 intact-crc:B839ED263261453D|rigid:bCg+aksTlLhvA+REs53aAclMOo0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40072 uniprotkb:P35179 intact:EBI-22661|uniprotkb:D3DM22|ensemblfungi:YER116C intact:EBI-16406|ensemblfungi:YDR086C|uniprotkb:D6VS73 psi-mi:slx8_yeast(display_long)|uniprotkb:SLX8(gene name)|psi-mi:SLX8(display_short)|uniprotkb:Synthetic lethal of unknown function protein 8(gene name synonym)|uniprotkb:YER116C(locus name)|uniprotkb:RING-type E3 ubiquitin transferase SLX8(gene name synonym) psi-mi:sc61g_yeast(display_long)|uniprotkb:Sec61 complex subunit SSS1(gene name synonym)|uniprotkb:Ssh1 complex subunit SSS1(gene name synonym)|uniprotkb:D4475(orf name)|uniprotkb:YDR086C(locus name)|uniprotkb:SSS1(gene name)|psi-mi:SSS1(display_short)|uniprotkb:Sec61 complex subunit gamma(gene name synonym)|uniprotkb:Ssh1 complex subunit gamma(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331659|imex:IM-14275-1612 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011041.3|sgd:S000000918|dip:DIP-1365N|mint:P40072|ensemblfungi:YER116C(gene)|ensemblfungi:YER116C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000776"(kinetochore)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016925"(protein sumoylation)|go:"GO:0033768"(SUMO-targeted ubiquitin ligase complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957 ensemblfungi:YDR086C(gene)|ensemblfungi:YDR086C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|rcsb pdb:2WW9|rcsb pdb:2WWA|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|reactome:R-SCE-9609523|refseq:NP_010371.1|sgd:S000002493|dip:DIP-2432N|mint:P35179 psi-mi:"MI:0469"(intact) crc64:358DB6D137155DC1 - figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:koTmyYWk4tUBikxl/yVUsmj+V/4559292 rogid:QIi5kN/8mDxTSvxRiJVi2JsPdws559292 intact-crc:CAB44350AC3CE299|rigid:1wQnfZnYEAAC1XSJamjCCzWzdcU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40073 uniprotkb:P09620 intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331670|imex:IM-14275-1613 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073 ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) crc64:E467A4D50AA3EDB6 - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:DPpJB36kZxbFXugXajgs899epuY559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:0EAC7B5A63BA7C19|rigid:6BAYpAup4sj7IKlKzYTk1SNTQFE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53188 uniprotkb:P40078 intact:EBI-23731|uniprotkb:D6VUA9|ensemblfungi:YGL029W intact:EBI-22681|uniprotkb:D3DM32|ensemblfungi:YER126C psi-mi:cgr1_yeast(display_long)|uniprotkb:YGL029W(locus name)|uniprotkb:CGR1(gene name)|psi-mi:CGR1(display_short)|uniprotkb:Coiled-coil growth-regulated protein 1(gene name synonym) psi-mi:nsa2_yeast(display_long)|uniprotkb:YER126C(locus name)|uniprotkb:SYGP-ORF47(orf name)|uniprotkb:NSA2(gene name)|psi-mi:NSA2(display_short)|uniprotkb:NOP7-associated protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331681|imex:IM-14275-1614 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011486.1|sgd:S000002997|dip:DIP-5450N|mint:P53188|ensemblfungi:YGL029W(gene)|ensemblfungi:YGL029W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR005579(Cgr1)|rcsb pdb:3JCT|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6YLG|rcsb pdb:6YLH refseq:NP_011052.1|sgd:S000000928|dip:DIP-1892N|mint:P40078|ensemblfungi:YER126C(gene)|ensemblfungi:YER126C_mRNA(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR022309|interpro:IPR039411|rcsb pdb:3JCT|rcsb pdb:4WJV|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:7BT6|rcsb pdb:7BTB psi-mi:"MI:0469"(intact) - crc64:545C8B4250BCB0C9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:G7SUf9/XRWXFaYG1LRPoChi6BVA559292 rogid:ru6dofBbaVkHM+0tunQ4n36y98M559292 intact-crc:500A1D08118280A0|rigid:HhqQugEkJvLUFll7gUInSCMo+Ck false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:P40088 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331692|imex:IM-14275-1615 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 intact-crc:FFCE0AB9E1D2032A|rigid:7gRwWRavcxJyVyv7ZdSw9rYdy40 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40088 uniprotkb:P10823 intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331703|imex:IM-14275-1616 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) - crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:3060F9424F46EE67|rigid:lcpCh44BCoKEXx8RZHGPelAmTRw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:P40088 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331714|imex:IM-14275-1617 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 intact-crc:18AB6D39B3DA5D09|rigid:rLop3bpx6BduLUx0LzJS0Ma4vKk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40088 uniprotkb:P30605 intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C intact:EBI-2050956|uniprotkb:D6VTB9|ensemblfungi:YDR497C psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:itr1_yeast(display_long)|uniprotkb:D9719.3(orf name)|uniprotkb:YDR497C(locus name)|uniprotkb:ITR1(gene name)|psi-mi:ITR1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331725|imex:IM-14275-1618 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) refseq:NP_010785.1|sgd:S000002905|dip:DIP-7406N|mint:P30605|ensemblfungi:YDR497C(gene)|ensemblfungi:YDR497C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 rogid:GgtK4YFe7ZCZcmVpV5q1KY2F0Ds559292 intact-crc:66C14A870B17280B|rigid:U4Le73WwoyRne7HCy1lBzOXnC90 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40088 uniprotkb:P32465 intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331736|imex:IM-14275-1619 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 intact-crc:03A4564510914ED3|rigid:XYDOtJTKwEfjjlOz6N2/UkAiATE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40088 uniprotkb:P33413 intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C intact:EBI-2060312|uniprotkb:D3DKP5|ensemblfungi:YHL016C psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:dur3_yeast(display_long)|uniprotkb:DUR3(gene name)|psi-mi:DUR3(display_short)|uniprotkb:YHL016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331747|imex:IM-14275-1620 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) interpro:IPR031155|refseq:NP_011847.1|sgd:S000001008|interpro:IPR001734(Na+/solute symporter)|interpro:IPR038377|mint:P33413|ensemblfungi:YHL016C(gene)|ensemblfungi:YHL016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0015204"(urea transmembrane transporter activity)|go:"GO:0015489"(putrescine transmembrane transporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015840"(urea transport)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 rogid:oTFsdtOngA3q5wCbhK/fpVlIsz0559292 intact-crc:F47DB93F80B6772B|rigid:z7PIV5MqTUq9WdGvs9JY7uWag90 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40088 uniprotkb:P35735 intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331758|imex:IM-14275-1621 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:D388796206D40992|rigid:NSPZ6LnzZwpKjeg+MEYMQqIhy3o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:P40088 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331769|imex:IM-14275-1622 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 intact-crc:D0666FC878857F25|rigid:4yH3x2lu8zZfhPcOMIk5doRHmhg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40088 uniprotkb:P38234 intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331780|imex:IM-14275-1623 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 intact-crc:3228B58BBBBBEAEC|rigid:MYXCsJWVYrmPZnUu9uvOXXRe1Pk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40088 uniprotkb:P38695 intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331791|imex:IM-14275-1624 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N psi-mi:"MI:0469"(intact) - crc64:6906721BAC1A5F87 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 intact-crc:AD5F318F2A41B8BA|rigid:zzlsgfJFDOR/J/g/zvbgbKQhEGM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40088 uniprotkb:P38993 intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C intact:EBI-6876|uniprotkb:D6VZN2|ensemblfungi:YMR058W psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:fet3_yeast(display_long)|uniprotkb:YM9796.11(orf name)|uniprotkb:YMR058W(locus name)|uniprotkb:FET3(gene name)|psi-mi:FET3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331802|imex:IM-14275-1625 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) refseq:NP_013774.1|sgd:S000004662|mint:P38993|dip:DIP-5314N|ensemblfungi:YMR058W(gene)|ensemblfungi:YMR058W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0010106"(cellular response to iron ion starvation)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0033215"(reductive iron assimilation)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0046688"(response to copper ion)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR001117(Multicopper oxidase, type 1)|interpro:IPR002355(Multicopper oxidase, copper-binding site)|interpro:IPR008972(Cupredoxin)|interpro:IPR011706(Multicopper oxidase, type 2)|interpro:IPR011707(Multicopper oxidase, type 3)|interpro:IPR033138|interpro:IPR044130|rcsb pdb:1ZPU psi-mi:"MI:0469"(intact) - crc64:71CB4352B87746E6 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 rogid:yagULld2pZWL/KMb7zOTq7s2emM559292 intact-crc:A4A81E94A56E3096|rigid:Dh0/CHgAvWj8wVhlaYwUMpPiKA8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39719 uniprotkb:P40088 intact:EBI-20703|uniprotkb:Q05165|uniprotkb:D6VPG5|ensemblfungi:YAL053W intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C psi-mi:flc2_yeast(display_long)|uniprotkb:YAL053W(locus name)|uniprotkb:FLC2(gene name)|psi-mi:FLC2(display_short)|uniprotkb:FAD transporter 2(gene name synonym)|uniprotkb:TRP-like ion channel FLC2(gene name synonym) psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331813|imex:IM-14275-1626 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009348.2|sgd:S000000049|ensemblfungi:YAL053W(gene)|ensemblfungi:YAL053W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241|go:"GO:0055085"(transmembrane transport)|dip:DIP-6708N|mint:P39719 dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:NOmMW54DNa0o7vM945DlZgVUy44559292 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 intact-crc:3946BD0911846EA4|rigid:eOtMmgEl+v+ZBY3WyiFI4dSV1jU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P40088 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331824|imex:IM-14275-1627 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 intact-crc:A62A8AAECD617CED|rigid:BCAMXEsLEH0N+lJ9q/USt21gHw4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53049 uniprotkb:P40088 intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331835|imex:IM-14275-1628 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 intact-crc:884E65E2AC312880|rigid:iAQJ4+qouCVC2Hiot8cAXsE5H4A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40088 uniprotkb:P53278 intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331846|imex:IM-14275-1629 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome) psi-mi:"MI:0469"(intact) - crc64:D482327C9274C026 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292 intact-crc:7AB51AABF5E721DE|rigid:064uUOl+wdaonOL5beDAZq0rXiI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40088 uniprotkb:P53283 intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331857|imex:IM-14275-1630 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 intact-crc:8BD76EE87FAF5EED|rigid:I2qDSO61QeO3TBRTMvmfSqOwabI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02785 uniprotkb:P40088 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331868|imex:IM-14275-1631 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 intact-crc:C2285EE5450191A2|rigid:ZmJmSti55DeQLZM/Tl59dJTKznE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:P40088 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331879|imex:IM-14275-1632 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 intact-crc:8C185BC8ECB1C6FF|rigid:g6pWs/1DKOuqeVc9tHdDfWXSdO4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06170 uniprotkb:P40088 intact:EBI-35994|uniprotkb:D6VYW8|ensemblfungi:YLR326W intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C psi-mi:yl326_yeast(display_long)|uniprotkb:YLR326W(locus name) psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331890|imex:IM-14275-1633 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013430.1|sgd:S000004318|mint:Q06170|dip:DIP-3995N|ensemblfungi:YLR326W(gene)|ensemblfungi:YLR326W_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR025187 dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) psi-mi:"MI:0469"(intact) crc64:724CD7833AA9B416 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ufkoj1kRp4Y9JTsgbL+3k8hzJyo559292 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 intact-crc:E20C1ADBEA0A9D62|rigid:ADgDYWtCkAkV71L08DWeozSo/qA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40088 uniprotkb:Q06451 intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C intact:EBI-34275|uniprotkb:D6W4F2|ensemblfungi:YPR156C psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:tpo3_yeast(display_long)|uniprotkb:TPO3(gene name)|psi-mi:TPO3(display_short)|uniprotkb:P9584.7(orf name)|uniprotkb:YPR156C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331901|imex:IM-14275-1634 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) refseq:NP_015482.1|sgd:S000006360|mint:Q06451|dip:DIP-3907N|ensemblfungi:YPR156C(gene)|ensemblfungi:YPR156C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - crc64:D260ED161F800502 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 rogid:oVpx7Bjk/mK2Q7+/j05tX3gHw7k559292 intact-crc:AD1E42B6A40B99AF|rigid:BLlfZUER5GPLAi7Z1MfuIDV8zio false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06689 uniprotkb:P40088 intact:EBI-38659|uniprotkb:D6VZ50|ensemblfungi:YLR413W intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C psi-mi:yl413_yeast(display_long)|uniprotkb:YLR413W(locus name) psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331912|imex:IM-14275-1635 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013517.1|sgd:S000004405|mint:Q06689|dip:DIP-5075N|ensemblfungi:YLR413W(gene)|ensemblfungi:YLR413W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0071944"(cell periphery)|interpro:IPR009571(SUR7) dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) psi-mi:"MI:0469"(intact) crc64:92E23436DC857E95 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AoTGKjLhw0NECrtuftZqLANonds559292 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 intact-crc:50A8318B1278A735|rigid:qzyt5wSjP5GgeAy+j1PPy/dzcBk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40088 uniprotkb:Q07651 intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331923|imex:IM-14275-1636 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:CC03AC9B0B4CF462|rigid:REJTbRLLJgtaN55N61CTgm/MYb8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40088 uniprotkb:Q08967 intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C intact:EBI-36673|uniprotkb:D6W3E9|ensemblfungi:YPL221W psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:flc1_yeast(display_long)|uniprotkb:FAD transporter 1(gene name synonym)|uniprotkb:FLC1(gene name)|psi-mi:FLC1(display_short)|uniprotkb:TRP-like ion channel protein FLC1(gene name synonym)|uniprotkb:Heme utilization factor 1(gene name synonym)|uniprotkb:Bypass of PAM1 protein 1(gene name synonym)|uniprotkb:HUF1(gene name synonym)|uniprotkb:YPL221W(locus name)|uniprotkb:BOP1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331934|imex:IM-14275-1637 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) refseq:NP_015103.1|sgd:S000006142|mint:Q08967|dip:DIP-3965N|ensemblfungi:YPL221W(gene)|ensemblfungi:YPL221W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055085"(transmembrane transport)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 rogid:r6CcZGEjxHUk2w0iBUBvnAPaFd4559292 intact-crc:7B8F02D632B038C3|rigid:t3ZuztN5ezeuRQ8ghu0wPRydv5k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40088 uniprotkb:Q12256 intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331945|imex:IM-14275-1638 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 intact-crc:3FC05D5DDD374D89|rigid:JKn71K8m8qsoEBtQfqOpyoqfIrk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12335 uniprotkb:P40088 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331956|imex:IM-14275-1639 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) psi-mi:"MI:0469"(intact) crc64:1056E7A1F3E82288 - figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 intact-crc:C79D4B646541B345|rigid:bgXzawvdzYKqNrbD7czdNh+NdKo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3E756 uniprotkb:P40088 intact:EBI-2044812|uniprotkb:D6VPX0|ensemblfungi:YBL029C-A intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C psi-mi:yb029_yeast(display_long)|uniprotkb:YBL029C-A(locus name) psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331967|imex:IM-14275-1640 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000007591|refseq:NP_076874.1|mint:Q3E756|ensemblfungi:YBL029C-A(gene)|ensemblfungi:YBL029C-A_mRNA(transcript)|go:"GO:0005886"(plasma membrane) dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Y9LDkESr65DK5SLFNTw1dBKeqPc559292 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 intact-crc:A412E389B901F03B|rigid:Xkxz1qt/Al0FXschV7CkmlkR3F8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39904 uniprotkb:P40094 intact:EBI-16418|uniprotkb:Q03379|ensemblfungi:YDR484W|uniprotkb:D6VTA7 intact:EBI-16605|ensemblfungi:YER157W|uniprotkb:D3DM64 psi-mi:vps52_yeast(display_long)|uniprotkb:VPS52(gene name)|psi-mi:VPS52(display_short)|uniprotkb:YDR484W(locus name)|uniprotkb:D8035.27(orf name)|uniprotkb:SAC2(gene name synonym)|uniprotkb:Suppressor of actin mutation protein 2(gene name synonym) psi-mi:cog3_yeast(display_long)|uniprotkb:COG3(gene name)|psi-mi:COG3(display_short)|uniprotkb:GRD20(gene name synonym)|uniprotkb:SEC34(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 3(gene name synonym)|uniprotkb:Protein SEC34(gene name synonym)|uniprotkb:YER157W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331978|imex:IM-14275-1641 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0090156"(cellular sphingolipid homeostasis)|interpro:IPR007258(Vps52/Sac2)|ensemblfungi:YDR484W(gene)|ensemblfungi:YDR484W_mRNA(transcript)|go:"GO:0000938"(GARP complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030029"(actin filament-based process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|refseq:NP_010772.1|sgd:S000002892|dip:DIP-3967N|mint:P39904 ensemblfungi:YER157W(gene)|ensemblfungi:YER157W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR007265(Sec34-like protein)|refseq:NP_011084.1|sgd:S000000959|dip:DIP-4728N|mint:P40094 psi-mi:"MI:0469"(intact) crc64:F2BF669A72A712C1 crc64:C7AFBE99010FE571 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rP85+ORjSwj4Ar24ZXjolXQCK98559292 rogid:R2r0ZW+nxrykdTHq1cJy9zOmvHo559292 intact-crc:A84C3D4828023715|rigid:JSYh+FWN3kD5gIoTk2Zo1WBwI5I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40094 uniprotkb:P40094 intact:EBI-16605|ensemblfungi:YER157W|uniprotkb:D3DM64 intact:EBI-16605|ensemblfungi:YER157W|uniprotkb:D3DM64 psi-mi:cog3_yeast(display_long)|uniprotkb:COG3(gene name)|psi-mi:COG3(display_short)|uniprotkb:GRD20(gene name synonym)|uniprotkb:SEC34(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 3(gene name synonym)|uniprotkb:Protein SEC34(gene name synonym)|uniprotkb:YER157W(locus name) psi-mi:cog3_yeast(display_long)|uniprotkb:COG3(gene name)|psi-mi:COG3(display_short)|uniprotkb:GRD20(gene name synonym)|uniprotkb:SEC34(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 3(gene name synonym)|uniprotkb:Protein SEC34(gene name synonym)|uniprotkb:YER157W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6331989|imex:IM-14275-1642 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER157W(gene)|ensemblfungi:YER157W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR007265(Sec34-like protein)|refseq:NP_011084.1|sgd:S000000959|dip:DIP-4728N|mint:P40094 ensemblfungi:YER157W(gene)|ensemblfungi:YER157W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR007265(Sec34-like protein)|refseq:NP_011084.1|sgd:S000000959|dip:DIP-4728N|mint:P40094 psi-mi:"MI:0469"(intact) crc64:C7AFBE99010FE571 crc64:C7AFBE99010FE571 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R2r0ZW+nxrykdTHq1cJy9zOmvHo559292 rogid:R2r0ZW+nxrykdTHq1cJy9zOmvHo559292 intact-crc:F848C2953018C13D|rigid:Fl/5tRPo+FzXVMSHd4o0e2zRato false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:P40094 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-16605|ensemblfungi:YER157W|uniprotkb:D3DM64 psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:cog3_yeast(display_long)|uniprotkb:COG3(gene name)|psi-mi:COG3(display_short)|uniprotkb:GRD20(gene name synonym)|uniprotkb:SEC34(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 3(gene name synonym)|uniprotkb:Protein SEC34(gene name synonym)|uniprotkb:YER157W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332000|imex:IM-14275-1643 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 ensemblfungi:YER157W(gene)|ensemblfungi:YER157W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR007265(Sec34-like protein)|refseq:NP_011084.1|sgd:S000000959|dip:DIP-4728N|mint:P40094 psi-mi:"MI:0469"(intact) - crc64:C7AFBE99010FE571 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:R2r0ZW+nxrykdTHq1cJy9zOmvHo559292 intact-crc:9F8C02D85662BA4F|rigid:yYCVCB8hXAOXIFMUigZBlZMJaMU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40096 uniprotkb:P53751 intact:EBI-11908|ensemblfungi:YER159C|uniprotkb:D3DM66 intact:EBI-28557|uniprotkb:D6W1P0|ensemblfungi:YNR065C psi-mi:ncb1_yeast(display_long)|uniprotkb:BUR6(gene name)|psi-mi:BUR6(display_short)|uniprotkb:NCB1(gene name synonym)|uniprotkb:Transcription repressor BUR6(gene name synonym)|uniprotkb:YER159C(locus name) psi-mi:yn94_yeast(display_long)|uniprotkb:N3539(orf name)|uniprotkb:YNR065C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332011|imex:IM-14275-1644 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER159C(gene)|ensemblfungi:YER159C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017054"(negative cofactor 2 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|interpro:IPR027116|go:"GO:0005634"(nucleus)|refseq:NP_011086.3|sgd:S000000961|mint:P40096|dip:DIP-2066N refseq:NP_014463.1|sgd:S000005348|dip:DIP-4251N|mint:P53751|ensemblfungi:YNR065C(gene)|ensemblfungi:YNR065C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778 psi-mi:"MI:0469"(intact) crc64:27341BD250973BA7 crc64:C0361878FE4DAB90 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:80vZFpRN7MVRN9/zvGyJI4ak7gA559292 rogid:7iodiUQu3ZxDDC4KQlI3CoYD1IE559292 intact-crc:B90E1BC9F4203DB0|rigid:W0AVt9aQPWcxd+Wb31e/K5dBv7I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40096 uniprotkb:Q92317 intact:EBI-11908|ensemblfungi:YER159C|uniprotkb:D3DM66 intact:EBI-37723|uniprotkb:O00064|uniprotkb:P87340|uniprotkb:Q04176|uniprotkb:D6VT30|ensemblfungi:YDR397C psi-mi:ncb1_yeast(display_long)|uniprotkb:BUR6(gene name)|psi-mi:BUR6(display_short)|uniprotkb:NCB1(gene name synonym)|uniprotkb:Transcription repressor BUR6(gene name synonym)|uniprotkb:YER159C(locus name) psi-mi:ncb2_yeast(display_long)|uniprotkb:NCB2(gene name)|psi-mi:NCB2(display_short)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Transcriptional repressor YDR1(gene name synonym)|uniprotkb:YDR397C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332022|imex:IM-14275-1645 author score:94.37 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER159C(gene)|ensemblfungi:YER159C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017054"(negative cofactor 2 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|interpro:IPR027116|go:"GO:0005634"(nucleus)|refseq:NP_011086.3|sgd:S000000961|mint:P40096|dip:DIP-2066N refseq:NP_010685.1|sgd:S000002805|dip:DIP-2067N|mint:Q92317|ensemblfungi:YDR397C(gene)|ensemblfungi:YDR397C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0017054"(negative cofactor 2 complex)|go:"GO:0045898"(regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|interpro:IPR042225 psi-mi:"MI:0469"(intact) crc64:27341BD250973BA7 crc64:E04EB0D6F7E8D91D figure legend:tables S3 and S4|author-confidence:94.37|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:80vZFpRN7MVRN9/zvGyJI4ak7gA559292 rogid:lqILVmsMA1YDORBEGe4Xp4dsBQA559292 intact-crc:F44A102AFD9E5465|rigid:6ywc7Vi9829MXjnQBR0tCDLKGMM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40155 uniprotkb:P40155 intact:EBI-13218|ensemblfungi:YNL214W|uniprotkb:D6W0X6 intact:EBI-13218|ensemblfungi:YNL214W|uniprotkb:D6W0X6 psi-mi:pex17_yeast(display_long)|uniprotkb:PEX17(gene name)|psi-mi:PEX17(display_short)|uniprotkb:PAS9(gene name synonym)|uniprotkb:YNL214W(locus name)|uniprotkb:N1319(orf name)|uniprotkb:Peroxin-17(gene name synonym) psi-mi:pex17_yeast(display_long)|uniprotkb:PEX17(gene name)|psi-mi:PEX17(display_short)|uniprotkb:PAS9(gene name synonym)|uniprotkb:YNL214W(locus name)|uniprotkb:N1319(orf name)|uniprotkb:Peroxin-17(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332033|imex:IM-14275-1646 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005158|refseq:NP_014185.1|ensemblfungi:YNL214W(gene)|ensemblfungi:YNL214W_mRNA(transcript)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990415"|go:"GO:1990429"(peroxisomal importomer complex)|mint:P40155|dip:DIP-2474N sgd:S000005158|refseq:NP_014185.1|ensemblfungi:YNL214W(gene)|ensemblfungi:YNL214W_mRNA(transcript)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990415"|go:"GO:1990429"(peroxisomal importomer complex)|mint:P40155|dip:DIP-2474N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:NwAQV8soH7a8K+3MI1/nMgHC2dk559292 rogid:NwAQV8soH7a8K+3MI1/nMgHC2dk559292 intact-crc:5E40DB7B3D11C68E|rigid:/yRtMQ5t1FeQRpEelThlwsSdRY4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40155 uniprotkb:P53112 intact:EBI-13218|ensemblfungi:YNL214W|uniprotkb:D6W0X6 intact:EBI-13212|uniprotkb:D6VTZ8|ensemblfungi:YGL153W psi-mi:pex17_yeast(display_long)|uniprotkb:PEX17(gene name)|psi-mi:PEX17(display_short)|uniprotkb:PAS9(gene name synonym)|uniprotkb:YNL214W(locus name)|uniprotkb:N1319(orf name)|uniprotkb:Peroxin-17(gene name synonym) psi-mi:pex14_yeast(display_long)|uniprotkb:PEX14(gene name)|psi-mi:PEX14(display_short)|uniprotkb:YGL153W(locus name)|uniprotkb:G1870(orf name)|uniprotkb:Peroxin-14(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332044|imex:IM-14275-1647 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005158|refseq:NP_014185.1|ensemblfungi:YNL214W(gene)|ensemblfungi:YNL214W_mRNA(transcript)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990415"|go:"GO:1990429"(peroxisomal importomer complex)|mint:P40155|dip:DIP-2474N sgd:S000003121|refseq:NP_011362.3|mint:P53112|dip:DIP-1749N|ensemblfungi:YGL153W(gene)|ensemblfungi:YGL153W_mRNA(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:1990415"|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR006785(Peroxisome membrane anchor protein Pex14p, N-terminal)|interpro:IPR025655|interpro:IPR036388|rcsb pdb:1N5Z|rcsb pdb:2V1R|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-9603798 psi-mi:"MI:0469"(intact) - crc64:B714D7DA045E2DCB figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:NwAQV8soH7a8K+3MI1/nMgHC2dk559292 rogid:eS7O3dwiT/56U30PI8bpJny+kZQ559292 intact-crc:B43F4214C8EFED11|rigid:EUkTfPO9qiXK3fGhj6trgvLRNTc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46956 uniprotkb:P40207 intact:EBI-13337|uniprotkb:E9P8T7|ensemblfungi:YJL117W|uniprotkb:D6VW67 intact:EBI-27272|uniprotkb:D6VZV7|ensemblfungi:YMR134W psi-mi:pho86_yeast(display_long)|uniprotkb:PHO86(gene name)|psi-mi:PHO86(display_short)|uniprotkb:J0744(orf name)|uniprotkb:YJL117W(locus name) psi-mi:erg29_yeast(display_long)|uniprotkb:ERG29(gene name)|psi-mi:ERG29(display_short)|uniprotkb:YM9375.03(orf name)|uniprotkb:YMR134W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332055|imex:IM-14275-1648 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012418.1|sgd:S000003653|interpro:IPR024297|ensemblfungi:YJL117W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0010966"(regulation of phosphate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051082"(unfolded protein binding)|ensemblfungi:YJL117W(gene)|mint:P46956|dip:DIP-2769N refseq:NP_013853.1|sgd:S000004741|mint:P40207|dip:DIP-4433N|ensemblfungi:YMR134W(gene)|ensemblfungi:YMR134W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) crc64:1CB19C9184BF1C48 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:JITWReptfMoij1Uy6y1e3Oa6dAs559292 rogid:6ByNiLUswj10x66D1WrAHOI9t7c559292 intact-crc:76567F11F0B0B7FA|rigid:z68VcowHRCZW5AodG0T68Y0DkiM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43593 uniprotkb:P40209 intact:EBI-19852|uniprotkb:D6VTP0|ensemblfungi:YFR010W intact:EBI-7347|uniprotkb:D6VZV9|ensemblfungi:YMR136W psi-mi:ubp6_yeast(display_long)|uniprotkb:UBP6(gene name)|psi-mi:UBP6(display_short)|uniprotkb:Ubiquitin-specific-processing protease 6(gene name synonym)|uniprotkb:Deubiquitinating enzyme 6(gene name synonym)|uniprotkb:Ubiquitin thioesterase 6(gene name synonym)|uniprotkb:YFR010W(locus name) psi-mi:gat2_yeast(display_long)|uniprotkb:YM9375.05(orf name)|uniprotkb:YMR136W(locus name)|uniprotkb:GAT2(gene name)|psi-mi:GAT2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332066|imex:IM-14275-1649 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116665.1|sgd:S000001906|ensemblfungi:YFR010W(gene)|ensemblfungi:YFR010W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR000626(Ubiquitin)|interpro:IPR028889|interpro:IPR029071|interpro:IPR038765|interpro:IPR044635|rcsb pdb:1VJV|rcsb pdb:5A5B|rcsb pdb:5MPC|reactome:R-SCE-5689880|dip:DIP-6731N|mint:P43593 refseq:NP_013856.1|sgd:S000004744|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|mint:P40209|ensemblfungi:YMR136W(gene)|ensemblfungi:YMR136W_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding) psi-mi:"MI:0469"(intact) crc64:DAE54D1F8AC9960C - figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:M4HqdW/7V42HuFuSm4y6z4Oz6tg559292 rogid:D9KVdLMpjrjceIWe9QfYq2EoDhI559292 intact-crc:30032499AF5A762B|rigid:qA0dxbK3CQsJ4YS3nSXPb5p8bM4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P52490 uniprotkb:P40210 intact:EBI-19777|uniprotkb:D6VS79|ensemblfungi:YDR092W intact:EBI-27280|uniprotkb:D6VZW3|ensemblfungi:YMR140W psi-mi:ubc13_yeast(display_long)|uniprotkb:UBC13(gene name)|psi-mi:UBC13(display_short)|uniprotkb:YDR092W(locus name)|uniprotkb:YD6652.04(orf name)|uniprotkb:Ubiquitin-protein ligase 13(gene name synonym)|uniprotkb:Ubiquitin carrier protein 13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 13(gene name synonym) psi-mi:sip5_yeast(display_long)|uniprotkb:YMR140W(locus name)|uniprotkb:YM9375.09(orf name)|uniprotkb:SIP5(gene name)|psi-mi:SIP5(display_short)|uniprotkb:SNF1-interacting protein 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332077|imex:IM-14275-1650 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002499|ensemblfungi:YDR092W(gene)|ensemblfungi:YDR092W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006301"(postreplication repair)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0044395"(protein targeting to vacuolar membrane)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1JAT|rcsb pdb:1JBB|rcsb pdb:2GMI|rcsb pdb:4FH1|rcsb pdb:5OJW|reactome:R-SCE-8866654|reactome:R-SCE-9020702|reactome:R-SCE-9646399|reactome:R-SCE-983168|refseq:NP_010377.3|dip:DIP-5486N|mint:P52490 sgd:S000004748|refseq:NP_013860.1|mint:P40210|dip:DIP-4656N|ensemblfungi:YMR140W(gene)|ensemblfungi:YMR140W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0042149"(cellular response to glucose starvation)|interpro:IPR039301 psi-mi:"MI:0469"(intact) crc64:445558F8F193275B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5nTtjUZ2IpzHhrj1UU6NlaRW53k559292 rogid:6WSFQ9V598lJW1o+h2DCP7vRyeA559292 intact-crc:97AE4F1576FABFEB|rigid:1npb75fmrdoE4dvW8xzkRoqePS4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40210 uniprotkb:P53152 intact:EBI-27280|uniprotkb:D6VZW3|ensemblfungi:YMR140W intact:EBI-11035|ensemblfungi:YGL087C|uniprotkb:D6VU57 psi-mi:sip5_yeast(display_long)|uniprotkb:YMR140W(locus name)|uniprotkb:YM9375.09(orf name)|uniprotkb:SIP5(gene name)|psi-mi:SIP5(display_short)|uniprotkb:SNF1-interacting protein 5(gene name synonym) psi-mi:mms2_yeast(display_long)|uniprotkb:MMS2(gene name)|psi-mi:MMS2(display_short)|uniprotkb:YGL087C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332088|imex:IM-14275-1651 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004748|refseq:NP_013860.1|mint:P40210|dip:DIP-4656N|ensemblfungi:YMR140W(gene)|ensemblfungi:YMR140W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0042149"(cellular response to glucose starvation)|interpro:IPR039301 go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006301"(postreplication repair)|ensemblfungi:YGL087C(gene)|ensemblfungi:YGL087C_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0016874"(ligase activity)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0044395"(protein targeting to vacuolar membrane)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:1JAT|rcsb pdb:2GMI|rcsb pdb:5OJW|reactome:R-SCE-8866654|reactome:R-SCE-9020702|reactome:R-SCE-9646399|reactome:R-SCE-983168|sgd:S000003055|refseq:NP_011428.1|mint:P53152|dip:DIP-5829N psi-mi:"MI:0469"(intact) - crc64:E1DA713C94378795 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6WSFQ9V598lJW1o+h2DCP7vRyeA559292 rogid:dthbFT/vOgnFoOeCLfng4kqOXwA559292 intact-crc:2AF4052E0A1FE4C9|rigid:/KXSCGth19WU0dZEkiNK5Z9YCW4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40343 uniprotkb:P38753 intact:EBI-20380|uniprotkb:D6W1I1|ensemblfungi:YNR006W intact:EBI-1382|uniprotkb:D3DKR2|ensemblfungi:YHL002W psi-mi:vps27_yeast(display_long)|uniprotkb:VPS27(gene name)|psi-mi:VPS27(display_short)|uniprotkb:YNR006W(locus name)|uniprotkb:N2038(orf name)|uniprotkb:DID7(gene name synonym)|uniprotkb:SSV17(gene name synonym)|uniprotkb:VPL23(gene name synonym)|uniprotkb:VPT27(gene name synonym)|uniprotkb:Golgi retention defective protein 11(gene name synonym)|uniprotkb:GRD11(gene name synonym) psi-mi:hse1_yeast(display_long)|uniprotkb:YHL002W(locus name)|uniprotkb:HSE1(gene name)|psi-mi:HSE1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332099|imex:IM-14275-1652 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005289|refseq:NP_014403.3|ensemblfungi:YNR006W(gene)|ensemblfungi:YNR006W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0140504"(microlipophagy)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|rcsb pdb:1O06|rcsb pdb:1Q0V|rcsb pdb:1Q0W|rcsb pdb:1VFY|rcsb pdb:2KDI|rcsb pdb:2PJW|rcsb pdb:3R42|rcsb pdb:6NJG|dip:DIP-1741N|mint:P40343 refseq:NP_011861.1|sgd:S000000994|ensemblfungi:YHL002W(gene)|ensemblfungi:YHL002W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046982"(protein heterodimerization activity)|dip:DIP-1742N|mint:P38753|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR036028|rcsb pdb:2PJW psi-mi:"MI:0469"(intact) crc64:76C4501B0EBC9C84 crc64:026267836BBADF69 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5ScB34gSI3x260kAGh/knEWupwA559292 rogid:hPRFtB/ZQ4DL37gCH3EvSxwbW7w559292 intact-crc:904FD87167227321|rigid:v536EqE/Gha39qmMZnLdHb6nDzY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40348 uniprotkb:P38629 intact:EBI-14992|uniprotkb:E9P8U1|uniprotkb:D6VWN9|ensemblfungi:YJR068W intact:EBI-15000|uniprotkb:D6W0Q3|ensemblfungi:YNL290W psi-mi:rfc2_yeast(display_long)|uniprotkb:RFC2(gene name)|psi-mi:RFC2(display_short)|uniprotkb:YJR068W(locus name)|uniprotkb:J1808(orf name)|uniprotkb:Activator 1 41 kDa subunit(gene name synonym) psi-mi:rfc3_yeast(display_long)|uniprotkb:RFC3(gene name)|psi-mi:RFC3(display_short)|uniprotkb:YNL290W(locus name)|uniprotkb:N0533(orf name)|uniprotkb:Activator 1 40 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332110|imex:IM-14275-1653 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003829|refseq:NP_012602.3|ensemblfungi:YJR068W(gene)|ensemblfungi:YJR068W_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0031389"(Rad17 RFC-like complex)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0031391"(Elg1 RFC-like complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|rcsb pdb:1SXJ|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-176187|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5696397|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-69091|dip:DIP-2528N|mint:P40348 refseq:NP_014109.1|sgd:S000005234|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0005829"(cytosol)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0007049"(cell cycle)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031389"(Rad17 RFC-like complex)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0031391"(Elg1 RFC-like complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|rcsb pdb:1SXJ|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-176187|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5696397|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-69091|ensemblfungi:YNL290W(gene)|ensemblfungi:YNL290W_mRNA(transcript)|dip:DIP-2529N|mint:P38629 psi-mi:"MI:0469"(intact) crc64:59B2C4223B0D13BF crc64:0170EDABAB5CEA52 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Z0Rwf5Gg3mAcfGIC8toCXrjnD2g559292 rogid:OtrWr5Jm6RHPAOzOBeiE1AZiw3g559292 intact-crc:1584FD06A895405F|rigid:R/hqLhoeQuUS1d4qCiJIGD+ly5E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06679 uniprotkb:P40362 intact:EBI-35712|uniprotkb:D6VSV7|ensemblfungi:YDR324C intact:EBI-4534|uniprotkb:D6VWB4|ensemblfungi:YJL069C psi-mi:utp4_yeast(display_long)|uniprotkb:UTP4(gene name)|psi-mi:UTP4(display_short)|uniprotkb:t-UTP4(gene name synonym)|uniprotkb:U three protein 4(gene name synonym)|uniprotkb:U3 protein 4 required for transcription(gene name synonym)|uniprotkb:YDR324C(locus name) psi-mi:utp18_yeast(display_long)|uniprotkb:YJL069C(locus name)|uniprotkb:J1098(orf name)|uniprotkb:HRE594(orf name)|uniprotkb:UTP18(gene name)|psi-mi:UTP18(display_short)|uniprotkb:U three protein 18(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332121|imex:IM-14275-1654 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010611.3|sgd:S000002732|mint:Q06679|dip:DIP-6436N|ensemblfungi:YDR324C(gene)|ensemblfungi:YDR324C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 refseq:NP_012466.1|sgd:S000003605|dip:DIP-6392N|mint:P40362|ensemblfungi:YJL069C(gene)|ensemblfungi:YJL069C_mRNA(transcript)|go:"GO:0000292"(RNA fragment catabolic process)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:5D1C77899CABB40B crc64:0FEBD4540CF039DA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kAD4RO628jpcbjUoQXQbjcGVY88559292 rogid:lmOAbQt7Qj6BTcyEZHjuQ1hFQTM559292 intact-crc:7DB475CF7EF824D1|rigid:Set+CgDjfpB2y90mMAFsrSRJZBQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40363 uniprotkb:P40363 intact:EBI-25922|uniprotkb:D6VWB5|ensemblfungi:YJL068C intact:EBI-25922|uniprotkb:D6VWB5|ensemblfungi:YJL068C psi-mi:sfgh_yeast(display_long)|uniprotkb:HRE299(orf name)|uniprotkb:J1102(orf name)|uniprotkb:YJL068C(locus name) psi-mi:sfgh_yeast(display_long)|uniprotkb:HRE299(orf name)|uniprotkb:J1102(orf name)|uniprotkb:YJL068C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332132|imex:IM-14275-1655 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012467.1|sgd:S000003604|mint:P40363|dip:DIP-4988N|ensemblfungi:YJL068C(gene)|ensemblfungi:YJL068C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0018738"(S-formylglutathione hydrolase activity)|go:"GO:0046294"(formaldehyde catabolic process)|go:"GO:0052689"(carboxylic ester hydrolase activity)|interpro:IPR000801(Putative esterase)|interpro:IPR014186(S-formylglutathione hydrolase)|interpro:IPR029058|rcsb pdb:1PV1|rcsb pdb:3C6B|rcsb pdb:4FLM|rcsb pdb:4FOL|reactome:R-SCE-156590 refseq:NP_012467.1|sgd:S000003604|mint:P40363|dip:DIP-4988N|ensemblfungi:YJL068C(gene)|ensemblfungi:YJL068C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0018738"(S-formylglutathione hydrolase activity)|go:"GO:0046294"(formaldehyde catabolic process)|go:"GO:0052689"(carboxylic ester hydrolase activity)|interpro:IPR000801(Putative esterase)|interpro:IPR014186(S-formylglutathione hydrolase)|interpro:IPR029058|rcsb pdb:1PV1|rcsb pdb:3C6B|rcsb pdb:4FLM|rcsb pdb:4FOL|reactome:R-SCE-156590 psi-mi:"MI:0469"(intact) crc64:BFA5DC02729E9AEF crc64:BFA5DC02729E9AEF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1l8v1d3V7Nalz/lTgMPbaFFyimM559292 rogid:1l8v1d3V7Nalz/lTgMPbaFFyimM559292 intact-crc:88E957DB1FD1F5A9|rigid:XXU6bMpLM0b1APIdZyPE4yGn/nY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14907 uniprotkb:P40368 intact:EBI-12265|uniprotkb:D6VWE3 intact:EBI-12331|ensemblfungi:YJL061W|uniprotkb:D6VWC1 psi-mi:nsp1_yeast(display_long)|uniprotkb:NSP1(gene name)|psi-mi:NSP1(display_short)|uniprotkb:YJL041W(locus name)|uniprotkb:J1207(orf name)|uniprotkb:Nuclear pore protein NSP1(gene name synonym)|uniprotkb:Nucleoskeletal-like protein(gene name synonym)|uniprotkb:p110(gene name synonym) psi-mi:nup82_yeast(display_long)|uniprotkb:NUP82(gene name)|psi-mi:NUP82(display_short)|uniprotkb:YJL061W(locus name)|uniprotkb:J1135(orf name)|uniprotkb:HRB187(orf name)|uniprotkb:Nuclear pore protein NUP82(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332143|imex:IM-14275-1656 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0097064"(ncRNA export from nucleus)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|rcsb pdb:1O6O|refseq:NP_012494.3|sgd:S000003577|mint:P14907|dip:DIP-1484N refseq:NP_012474.1|sgd:S000003597|ensemblfungi:YJL061W(gene)|ensemblfungi:YJL061W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|interpro:IPR037700|rcsb pdb:3PBP|rcsb pdb:3TKN|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|mint:P40368|dip:DIP-913N psi-mi:"MI:0469"(intact) crc64:A258003CB1917810 crc64:C379B5E111E26B50 figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wFdC6D8JzkhJpF+k3qtnFj9+4pA559292 rogid:g1+jqOMmde8phrNI9H7nFlXwjH0559292 intact-crc:5F7B4F6C4AF726F8|rigid:5pX7r8bGLkiSY4n6mSws4mqITUw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35729 uniprotkb:P40368 intact:EBI-11713|ensemblfungi:YKL057C|uniprotkb:P35730|uniprotkb:D6VXN0 intact:EBI-12331|ensemblfungi:YJL061W|uniprotkb:D6VWC1 psi-mi:nu120_yeast(display_long)|uniprotkb:NUP120(gene name)|psi-mi:NUP120(display_short)|uniprotkb:RAT2(gene name synonym)|uniprotkb:YKL057C(locus name)|uniprotkb:YKL314(orf name)|uniprotkb:YKL313(orf name)|uniprotkb:Nuclear pore protein NUP120(gene name synonym) psi-mi:nup82_yeast(display_long)|uniprotkb:NUP82(gene name)|psi-mi:NUP82(display_short)|uniprotkb:YJL061W(locus name)|uniprotkb:J1135(orf name)|uniprotkb:HRB187(orf name)|uniprotkb:Nuclear pore protein NUP82(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332154|imex:IM-14275-1657 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YKL057C(gene)|ensemblfungi:YKL057C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR021717|rcsb pdb:3F7F|go:"GO:0031509"(subtelomeric heterochromatin assembly)|rcsb pdb:3H7N|rcsb pdb:3HXR|rcsb pdb:4XMM|rcsb pdb:4XMN|rcsb pdb:6X06|refseq:NP_012866.1|sgd:S000001540|mint:P35729|dip:DIP-2721N refseq:NP_012474.1|sgd:S000003597|ensemblfungi:YJL061W(gene)|ensemblfungi:YJL061W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|interpro:IPR037700|rcsb pdb:3PBP|rcsb pdb:3TKN|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|mint:P40368|dip:DIP-913N psi-mi:"MI:0469"(intact) crc64:D4655E6116C54503 crc64:C379B5E111E26B50 figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8A1GtKeq+kjBvl1iuUd6rIx7yLo559292 rogid:g1+jqOMmde8phrNI9H7nFlXwjH0559292 intact-crc:4C21B3EDE56A2639|rigid:NsgiikstjvS/xSRCLhrMHahXsHY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40368 uniprotkb:P40368 intact:EBI-12331|ensemblfungi:YJL061W|uniprotkb:D6VWC1 intact:EBI-12331|ensemblfungi:YJL061W|uniprotkb:D6VWC1 psi-mi:nup82_yeast(display_long)|uniprotkb:NUP82(gene name)|psi-mi:NUP82(display_short)|uniprotkb:YJL061W(locus name)|uniprotkb:J1135(orf name)|uniprotkb:HRB187(orf name)|uniprotkb:Nuclear pore protein NUP82(gene name synonym) psi-mi:nup82_yeast(display_long)|uniprotkb:NUP82(gene name)|psi-mi:NUP82(display_short)|uniprotkb:YJL061W(locus name)|uniprotkb:J1135(orf name)|uniprotkb:HRB187(orf name)|uniprotkb:Nuclear pore protein NUP82(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332165|imex:IM-14275-1658 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012474.1|sgd:S000003597|ensemblfungi:YJL061W(gene)|ensemblfungi:YJL061W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|interpro:IPR037700|rcsb pdb:3PBP|rcsb pdb:3TKN|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|mint:P40368|dip:DIP-913N refseq:NP_012474.1|sgd:S000003597|ensemblfungi:YJL061W(gene)|ensemblfungi:YJL061W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|interpro:IPR037700|rcsb pdb:3PBP|rcsb pdb:3TKN|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|mint:P40368|dip:DIP-913N psi-mi:"MI:0469"(intact) crc64:C379B5E111E26B50 crc64:C379B5E111E26B50 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:g1+jqOMmde8phrNI9H7nFlXwjH0559292 rogid:g1+jqOMmde8phrNI9H7nFlXwjH0559292 intact-crc:7EEA13A872298F25|rigid:ZpWwbqqhhYSTwULiwA4fizA3JLs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40368 uniprotkb:Q02630 intact:EBI-12331|ensemblfungi:YJL061W|uniprotkb:D6VWC1 intact:EBI-11703|ensemblfungi:YMR047C|uniprotkb:D6VZM2 psi-mi:nup82_yeast(display_long)|uniprotkb:NUP82(gene name)|psi-mi:NUP82(display_short)|uniprotkb:YJL061W(locus name)|uniprotkb:J1135(orf name)|uniprotkb:HRB187(orf name)|uniprotkb:Nuclear pore protein NUP82(gene name synonym) psi-mi:nu116_yeast(display_long)|uniprotkb:NUP116(gene name)|psi-mi:NUP116(display_short)|uniprotkb:NSP116(gene name synonym)|uniprotkb:YMR047C(locus name)|uniprotkb:YM9532.12C(orf name)|uniprotkb:Nuclear pore protein NUP116/NSP116(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332176|imex:IM-14275-1659 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012474.1|sgd:S000003597|ensemblfungi:YJL061W(gene)|ensemblfungi:YJL061W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|interpro:IPR037700|rcsb pdb:3PBP|rcsb pdb:3TKN|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|mint:P40368|dip:DIP-913N ensemblfungi:YMR047C(gene)|ensemblfungi:YMR047C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0051117"(ATPase binding)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|rcsb pdb:1O6P|rcsb pdb:2AIV|rcsb pdb:3PBP|go:"GO:0017056"(structural constituent of nuclear pore)|refseq:NP_013762.1|sgd:S000004650|mint:Q02630|dip:DIP-2389N psi-mi:"MI:0469"(intact) crc64:C379B5E111E26B50 crc64:FBAB0B9AEA958213 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:g1+jqOMmde8phrNI9H7nFlXwjH0559292 rogid:ZuiHiCdDSP9OqFdd1+fJ07WNe7Y559292 intact-crc:DE4686A6992A3358|rigid:lH8qfuqP3Qzj0kBtb0MSJ+cLOck false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40414 uniprotkb:P40414 intact:EBI-19419|uniprotkb:D6VVE8|ensemblfungi:YIL138C intact:EBI-19419|uniprotkb:D6VVE8|ensemblfungi:YIL138C psi-mi:tpm2_yeast(display_long)|uniprotkb:YIL138C(locus name)|uniprotkb:TPM2(gene name)|psi-mi:TPM2(display_short) psi-mi:tpm2_yeast(display_long)|uniprotkb:YIL138C(locus name)|uniprotkb:TPM2(gene name)|psi-mi:TPM2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332187|imex:IM-14275-1660 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001400|ensemblfungi:YIL138C(gene)|ensemblfungi:YIL138C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003786"(actin lateral binding)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005884"(actin filament)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|interpro:IPR000533(Tropomyosin)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007119"(budding cell isotropic bud growth)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0032432"(actin filament bundle)|refseq:NP_012128.3|dip:DIP-2201N|mint:P40414 sgd:S000001400|ensemblfungi:YIL138C(gene)|ensemblfungi:YIL138C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003786"(actin lateral binding)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005884"(actin filament)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|interpro:IPR000533(Tropomyosin)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007119"(budding cell isotropic bud growth)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0032432"(actin filament bundle)|refseq:NP_012128.3|dip:DIP-2201N|mint:P40414 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:/V6RhsoBaanxDVJ4SSAfev2tvnk559292 rogid:/V6RhsoBaanxDVJ4SSAfev2tvnk559292 intact-crc:1F45F0280856CD3A|rigid:csGo5f0IwBxhMihvTdWxlG57DjY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40433 uniprotkb:Q08748 intact:EBI-1956|uniprotkb:D6VVI0|ensemblfungi:YIL107C intact:EBI-2050125|uniprotkb:D6W2Z5|ensemblfungi:YOR296W psi-mi:6p21_yeast(display_long)|uniprotkb:PFK26(gene name)|psi-mi:PFK26(display_short)|uniprotkb:Phosphofructokinase 2 I(gene name synonym)|uniprotkb:YIL107C(locus name) psi-mi:yo296_yeast(display_long)|uniprotkb:YOR296W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332198|imex:IM-14275-1661 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012159.1|sgd:S000001369|interpro:IPR003094(Fructose-2,6-bisphosphatase)|interpro:IPR013079(6-phosphofructo-2-kinase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|interpro:IPR027417|mint:P40433|ensemblfungi:YIL107C(gene)|ensemblfungi:YIL107C_mRNA(transcript)|go:"GO:0003873"(6-phosphofructo-2-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006003"(fructose 2,6-bisphosphate metabolic process) refseq:NP_014939.1|sgd:S000005822|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR014770(Munc13 homology 1)|interpro:IPR014772(Munc13 homology 2)|interpro:IPR019558|mint:Q08748|interpro:IPR035892|ensemblfungi:YOR296W(gene)|ensemblfungi:YOR296W_mRNA(transcript)|go:"GO:0005737"(cytoplasm) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wD0zRE5Pddk4Vo54+4WuMoT940w559292 rogid:SMFMKeDnBPQzBm5c8hrj9GOokpg559292 intact-crc:19ABD2A5CF0993B7|rigid:SqyF3/cl5P9xbtDmaqdbOrjmubM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40463 uniprotkb:P26570 intact:EBI-25234|uniprotkb:D6VVF1|ensemblfungi:YIL135C intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 psi-mi:vhs2_yeast(display_long)|uniprotkb:VHS2(gene name)|psi-mi:VHS2(display_short)|uniprotkb:YIL135C(locus name)|uniprotkb:Viable in a HAL3 SIT4 background protein 2(gene name synonym) psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332209|imex:IM-14275-1662 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001397|refseq:NP_012131.1|mint:P40463|dip:DIP-5269N|ensemblfungi:YIL135C(gene)|ensemblfungi:YIL135C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032186"(cellular bud neck septin ring organization) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N psi-mi:"MI:0469"(intact) crc64:FDD206463FBFF234 crc64:8B7F009521F72C15 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:DcY9iGRvU2nLdlleLia/97PEOh8559292 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 intact-crc:121610E4B5627D35|rigid:HiKo7UyM3rN/2w7FYUj7HpwmWyA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40463 uniprotkb:P36076 intact:EBI-25234|uniprotkb:D6VVF1|ensemblfungi:YIL135C intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W psi-mi:vhs2_yeast(display_long)|uniprotkb:VHS2(gene name)|psi-mi:VHS2(display_short)|uniprotkb:YIL135C(locus name)|uniprotkb:Viable in a HAL3 SIT4 background protein 2(gene name synonym) psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332220|imex:IM-14275-1663 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001397|refseq:NP_012131.1|mint:P40463|dip:DIP-5269N|ensemblfungi:YIL135C(gene)|ensemblfungi:YIL135C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032186"(cellular bud neck septin ring organization) refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783 psi-mi:"MI:0469"(intact) crc64:FDD206463FBFF234 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:DcY9iGRvU2nLdlleLia/97PEOh8559292 rogid:Li7vZOassm4PC5fW111/j5ivgEc559292 intact-crc:7EF90B105B616422|rigid:NILWTsNgCRF+FrID/F+AwWl5Hm4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40469 uniprotkb:P38829 intact:EBI-11492|uniprotkb:P89106|uniprotkb:Q45U11|uniprotkb:D6VVF9|ensemblfungi:YIL128W intact:EBI-24704|uniprotkb:D3DL72|ensemblfungi:YHR122W psi-mi:met18_yeast(display_long)|uniprotkb:MMS19(gene name synonym)|uniprotkb:MET18(gene name)|psi-mi:MET18(display_short)|uniprotkb:Methyl methanesulfonate-sensitivity protein 19(gene name synonym)|uniprotkb:YIL128W(locus name) psi-mi:yhs2_yeast(display_long)|uniprotkb:YHR122W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332231|imex:IM-14275-1664 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YIL128W(gene)|ensemblfungi:YIL128W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0009411"(response to UV)|go:"GO:0010033"(response to organic substance)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024687|interpro:IPR029240|interpro:IPR039920|refseq:NP_012138.1|sgd:S000001390|mint:P40469|dip:DIP-1438N refseq:NP_011990.1|sgd:S000001164|dip:DIP-1837N|mint:P38829|ensemblfungi:YHR122W(gene)|ensemblfungi:YHR122W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0097361"(CIA complex)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR002744(Protein of unknown function DUF59)|interpro:IPR034904|interpro:IPR039796 psi-mi:"MI:0469"(intact) crc64:D05DCC488E098814 crc64:0C5AF75D54C77BCA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aGHI860LyIouqzxBbYcEPKipQWs559292 rogid:wxEWSVEULCGKJmSvX3FzB9ejcaU559292 intact-crc:652C5419F0E66BA3|rigid:n1BEYwrrBje0Vs5f3NAHFtGN6Go false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:P40474 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332242|imex:IM-14275-1665 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 intact-crc:1AA1811CE4E72E45|rigid:iW5AjzGdbPd8PkKNJXNfTdGafto false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:P40474 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332253|imex:IM-14275-1666 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 intact-crc:01AEBA6047AC3D9F|rigid:mGugZ/ZXVZAzBSIUJPD/32vxC+0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40474 uniprotkb:P32568 intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332264|imex:IM-14275-1667 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 intact-crc:C246A833E4FBBBBC|rigid:xT6hchkUf1pj2E+KrW/6y99/3nw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40474 uniprotkb:P33302 intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W intact:EBI-13038|uniprotkb:D6W2L0|ensemblfungi:YOR153W psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:pdr5_yeast(display_long)|uniprotkb:PDR5(gene name)|psi-mi:PDR5(display_short)|uniprotkb:LEM1(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 5(gene name synonym)|uniprotkb:Suppressor of toxicity of sporidesmin(gene name synonym)|uniprotkb:YOR153W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332275|imex:IM-14275-1668 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 sgd:S000005679|refseq:NP_014796.3|mint:P33302|dip:DIP-6776N|ensemblfungi:YOR153W(gene)|ensemblfungi:YOR153W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR029481|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 rogid:Sd6SJWf6B0rDZnLVaPHyvr4lhew559292 intact-crc:209A721E6E50D7D1|rigid:nMJg3yuznuwLZI3xbIvNH5M2QUU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P40474 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332286|imex:IM-14275-1669 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 intact-crc:D185E62751E97ADE|rigid:Qru55Plqyc/au/nR3BnIdE8HbUg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:P40474 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332297|imex:IM-14275-1670 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 intact-crc:D26C83ED2FB80C69|rigid:d9o7F1tBVjPFaoMlMI2UkEkfkn4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40474 uniprotkb:P38234 intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332308|imex:IM-14275-1671 author score:99.34 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.34|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 intact-crc:30249B7EEC8699A0|rigid:FZUsBPYFfQqtUdWZmtdJBqfZS+c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40474 uniprotkb:P40474 intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332319|imex:IM-14275-1672 author score:99.34 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.34|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 intact-crc:5BC4A4C2C705E1AE|rigid:4V286o8z0opyW3mUyIOWIAJwPGk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P40474 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332330|imex:IM-14275-1673 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 intact-crc:56B80E99E9808A18|rigid:QOrk4e6Nys2HxhkenV+5bymm4SI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40474 uniprotkb:Q02785 intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332341|imex:IM-14275-1674 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:32BADAD261E06757|rigid:m8+caLGKoqhQ+kvED7wAJw5V9rc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40474 uniprotkb:Q03640 intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332352|imex:IM-14275-1675 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) - crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:7C8ADFFFC850300A|rigid:2ILF3DtX27tERtUrWQONVZn3faI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06689 uniprotkb:P40474 intact:EBI-38659|uniprotkb:D6VZ50|ensemblfungi:YLR413W intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W psi-mi:yl413_yeast(display_long)|uniprotkb:YLR413W(locus name) psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332363|imex:IM-14275-1676 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013517.1|sgd:S000004405|mint:Q06689|dip:DIP-5075N|ensemblfungi:YLR413W(gene)|ensemblfungi:YLR413W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0071944"(cell periphery)|interpro:IPR009571(SUR7) refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:92E23436DC857E95 - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AoTGKjLhw0NECrtuftZqLANonds559292 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 intact-crc:A03DC6DC369951C0|rigid:Y/dkrCNn2iX7Xcegdo+JfXw05pQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40474 uniprotkb:Q07824 intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332374|imex:IM-14275-1677 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 intact-crc:C23F1EAD0C941B90|rigid:V9qL36+W/fOiRFE+Lg6cmp8M9N0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40474 uniprotkb:Q3E756 intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W intact:EBI-2044812|uniprotkb:D6VPX0|ensemblfungi:YBL029C-A psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:yb029_yeast(display_long)|uniprotkb:YBL029C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332385|imex:IM-14275-1678 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 sgd:S000007591|refseq:NP_076874.1|mint:Q3E756|ensemblfungi:YBL029C-A(gene)|ensemblfungi:YBL029C-A_mRNA(transcript)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 rogid:Y9LDkESr65DK5SLFNTw1dBKeqPc559292 intact-crc:548067BE9DE006CE|rigid:MvCkbIAPGmCV1I2UF74PuGiEk2w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40477 uniprotkb:P40064 intact:EBI-11747|ensemblfungi:YIL115C|uniprotkb:D6VVH2 intact:EBI-11740|ensemblfungi:YER105C|uniprotkb:D3DM12 psi-mi:nu159_yeast(display_long)|uniprotkb:NUP158(gene name synonym)|uniprotkb:YIL115C(locus name)|uniprotkb:NUP159(gene name)|psi-mi:NUP159(display_short)|uniprotkb:RAT7(gene name synonym)|uniprotkb:Nuclear pore protein NUP159(gene name synonym) psi-mi:nu157_yeast(display_long)|uniprotkb:YER105C(locus name)|uniprotkb:NUP157(gene name)|psi-mi:NUP157(display_short)|uniprotkb:Nuclear pore protein NUP157(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332396|imex:IM-14275-1679 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YIL115C(gene)|ensemblfungi:YIL115C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0061912"(selective autophagy)|go:"GO:0097064"(ncRNA export from nucleus)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR039462|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|rcsb pdb:1XIP|rcsb pdb:3PBP|rcsb pdb:3RRM|rcsb pdb:3TKN|rcsb pdb:4DS1|refseq:NP_012151.1|sgd:S000001377|mint:P40477|dip:DIP-2314N ensemblfungi:YER105C(gene)|ensemblfungi:YER105C_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|rcsb pdb:4MHC|refseq:NP_011031.1|sgd:S000000907|mint:P40064|dip:DIP-846N psi-mi:"MI:0469"(intact) crc64:A33FFA52378F8205 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zoNwE4GaFG+YrQQO/qgaq9iHky8559292 rogid:vKznZjOxKUw5Bo+4LemfCkzdBxg559292 intact-crc:FE140540B3DBBBA3|rigid:ZpgIqJbCt5qCTbm8y10dJGdHmN4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40368 uniprotkb:P40477 intact:EBI-12331|ensemblfungi:YJL061W|uniprotkb:D6VWC1 intact:EBI-11747|ensemblfungi:YIL115C|uniprotkb:D6VVH2 psi-mi:nup82_yeast(display_long)|uniprotkb:NUP82(gene name)|psi-mi:NUP82(display_short)|uniprotkb:YJL061W(locus name)|uniprotkb:J1135(orf name)|uniprotkb:HRB187(orf name)|uniprotkb:Nuclear pore protein NUP82(gene name synonym) psi-mi:nu159_yeast(display_long)|uniprotkb:NUP158(gene name synonym)|uniprotkb:YIL115C(locus name)|uniprotkb:NUP159(gene name)|psi-mi:NUP159(display_short)|uniprotkb:RAT7(gene name synonym)|uniprotkb:Nuclear pore protein NUP159(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332407|imex:IM-14275-1680 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012474.1|sgd:S000003597|ensemblfungi:YJL061W(gene)|ensemblfungi:YJL061W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|interpro:IPR037700|rcsb pdb:3PBP|rcsb pdb:3TKN|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|mint:P40368|dip:DIP-913N ensemblfungi:YIL115C(gene)|ensemblfungi:YIL115C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0061912"(selective autophagy)|go:"GO:0097064"(ncRNA export from nucleus)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR039462|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|rcsb pdb:1XIP|rcsb pdb:3PBP|rcsb pdb:3RRM|rcsb pdb:3TKN|rcsb pdb:4DS1|refseq:NP_012151.1|sgd:S000001377|mint:P40477|dip:DIP-2314N psi-mi:"MI:0469"(intact) crc64:C379B5E111E26B50 crc64:A33FFA52378F8205 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:g1+jqOMmde8phrNI9H7nFlXwjH0559292 rogid:zoNwE4GaFG+YrQQO/qgaq9iHky8559292 intact-crc:1125A677ADFCDF31|rigid:M/OXH5uJmxGNOcwbHxe1PeIA2JE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40477 uniprotkb:Q02630 intact:EBI-11747|ensemblfungi:YIL115C|uniprotkb:D6VVH2 intact:EBI-11703|ensemblfungi:YMR047C|uniprotkb:D6VZM2 psi-mi:nu159_yeast(display_long)|uniprotkb:NUP158(gene name synonym)|uniprotkb:YIL115C(locus name)|uniprotkb:NUP159(gene name)|psi-mi:NUP159(display_short)|uniprotkb:RAT7(gene name synonym)|uniprotkb:Nuclear pore protein NUP159(gene name synonym) psi-mi:nu116_yeast(display_long)|uniprotkb:NUP116(gene name)|psi-mi:NUP116(display_short)|uniprotkb:NSP116(gene name synonym)|uniprotkb:YMR047C(locus name)|uniprotkb:YM9532.12C(orf name)|uniprotkb:Nuclear pore protein NUP116/NSP116(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332418|imex:IM-14275-1681 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YIL115C(gene)|ensemblfungi:YIL115C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0061912"(selective autophagy)|go:"GO:0097064"(ncRNA export from nucleus)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR039462|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|rcsb pdb:1XIP|rcsb pdb:3PBP|rcsb pdb:3RRM|rcsb pdb:3TKN|rcsb pdb:4DS1|refseq:NP_012151.1|sgd:S000001377|mint:P40477|dip:DIP-2314N ensemblfungi:YMR047C(gene)|ensemblfungi:YMR047C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0051117"(ATPase binding)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|rcsb pdb:1O6P|rcsb pdb:2AIV|rcsb pdb:3PBP|go:"GO:0017056"(structural constituent of nuclear pore)|refseq:NP_013762.1|sgd:S000004650|mint:Q02630|dip:DIP-2389N psi-mi:"MI:0469"(intact) crc64:A33FFA52378F8205 crc64:FBAB0B9AEA958213 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zoNwE4GaFG+YrQQO/qgaq9iHky8559292 rogid:ZuiHiCdDSP9OqFdd1+fJ07WNe7Y559292 intact-crc:06ABA19C44287372|rigid:q2xgjkAnJauPakJq+0HtI9SAjSI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38810 uniprotkb:P40482 intact:EBI-17012|uniprotkb:D3DL48|ensemblfungi:YHR098C intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8 psi-mi:sfb3_yeast(display_long)|uniprotkb:SFB3(gene name)|psi-mi:SFB3(display_short)|uniprotkb:SEC24-related protein 3(gene name synonym)|uniprotkb:Lethal with SEC13 protein 1(gene name synonym)|uniprotkb:LST1(gene name synonym)|uniprotkb:YHR098C(locus name) psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332429|imex:IM-14275-1682 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011966.1|sgd:S000001140|ensemblfungi:YHR098C(gene)|ensemblfungi:YHR098C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|interpro:IPR036174|go:"GO:0030127"(COPII vesicle coat)|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0043332"(mating projection tip)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071944"(cell periphery)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|dip:DIP-2949N|mint:P38810 refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482 psi-mi:"MI:0469"(intact) crc64:6A028AD6B1A2E031 crc64:35E2BDD24CC75899 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+UqTvqDtF6TcA3pcbFJfvzKsoyc559292 rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292 intact-crc:5DB04E000FD93034|rigid:OvT+FwN06oRhFgZocTgPao+9igo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04410 uniprotkb:P40482 intact:EBI-32083|uniprotkb:D6VTD8|ensemblfungi:YDR517W intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8 psi-mi:grh1_yeast(display_long)|uniprotkb:GRH1(gene name)|psi-mi:GRH1(display_short)|uniprotkb:YDR517W(locus name) psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332440|imex:IM-14275-1683 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010805.1|sgd:S000002925|dip:DIP-6613N|mint:Q04410|ensemblfungi:YDR517W(gene)|ensemblfungi:YDR517W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0009306"(protein secretion)|go:"GO:0031090"(organelle membrane)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR007583(GRASP55/65)|interpro:IPR024958|interpro:IPR036034|rcsb pdb:6G8Y|reactome:R-SCE-162658|reactome:R-SCE-204005 refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482 psi-mi:"MI:0469"(intact) crc64:A7CE62DFE4631214 crc64:35E2BDD24CC75899 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Tj4Jf1BeT57ROzFoNoi+g9GLuYk559292 rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292 intact-crc:991A8B2FFA535DBB|rigid:J9ErTqfDCfGQHQDt8Xy1+ekg9ik false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40485 uniprotkb:P10823 intact:EBI-25172|uniprotkb:D6VVI2|ensemblfungi:YIL105C intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:slm1_yeast(display_long)|uniprotkb:TORC2 effector protein SLM1(gene name synonym)|uniprotkb:Synthetic lethal with MSS4 protein 1(gene name synonym)|uniprotkb:YIL105C(locus name)|uniprotkb:SLM1(gene name)|psi-mi:SLM1(display_short)|uniprotkb:LIT2(gene name synonym) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332451|imex:IM-14275-1684 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012161.1|sgd:S000001367|mint:P40485|dip:DIP-1353N|ensemblfungi:YIL105C(gene)|ensemblfungi:YIL105C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070941"(eisosome assembly)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR033191|interpro:IPR043453|rcsb pdb:3NSU|rcsb pdb:4A5K|rcsb pdb:4A6F|rcsb pdb:4A6H|rcsb pdb:4A6K sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) crc64:849C82CC0960014B crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:f0Gtntpff7Oav37jlVaggG2VI30559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:A1B0FBF9FE59AC16|rigid:/k2PIAs5gW7qHsdGReRSwrsnNTU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:P40485 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-25172|uniprotkb:D6VVI2|ensemblfungi:YIL105C psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:slm1_yeast(display_long)|uniprotkb:TORC2 effector protein SLM1(gene name synonym)|uniprotkb:Synthetic lethal with MSS4 protein 1(gene name synonym)|uniprotkb:YIL105C(locus name)|uniprotkb:SLM1(gene name)|psi-mi:SLM1(display_short)|uniprotkb:LIT2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332462|imex:IM-14275-1685 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) refseq:NP_012161.1|sgd:S000001367|mint:P40485|dip:DIP-1353N|ensemblfungi:YIL105C(gene)|ensemblfungi:YIL105C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070941"(eisosome assembly)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR033191|interpro:IPR043453|rcsb pdb:3NSU|rcsb pdb:4A5K|rcsb pdb:4A6F|rcsb pdb:4A6H|rcsb pdb:4A6K psi-mi:"MI:0469"(intact) - crc64:849C82CC0960014B figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:f0Gtntpff7Oav37jlVaggG2VI30559292 intact-crc:8979BA220AE51F78|rigid:Wh4XDC960Pfbcv8VO51VROSwMGg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33413 uniprotkb:P40485 intact:EBI-2060312|uniprotkb:D3DKP5|ensemblfungi:YHL016C intact:EBI-25172|uniprotkb:D6VVI2|ensemblfungi:YIL105C psi-mi:dur3_yeast(display_long)|uniprotkb:DUR3(gene name)|psi-mi:DUR3(display_short)|uniprotkb:YHL016C(locus name) psi-mi:slm1_yeast(display_long)|uniprotkb:TORC2 effector protein SLM1(gene name synonym)|uniprotkb:Synthetic lethal with MSS4 protein 1(gene name synonym)|uniprotkb:YIL105C(locus name)|uniprotkb:SLM1(gene name)|psi-mi:SLM1(display_short)|uniprotkb:LIT2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332473|imex:IM-14275-1686 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031155|refseq:NP_011847.1|sgd:S000001008|interpro:IPR001734(Na+/solute symporter)|interpro:IPR038377|mint:P33413|ensemblfungi:YHL016C(gene)|ensemblfungi:YHL016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0015204"(urea transmembrane transporter activity)|go:"GO:0015489"(putrescine transmembrane transporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015840"(urea transport)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery) refseq:NP_012161.1|sgd:S000001367|mint:P40485|dip:DIP-1353N|ensemblfungi:YIL105C(gene)|ensemblfungi:YIL105C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070941"(eisosome assembly)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR033191|interpro:IPR043453|rcsb pdb:3NSU|rcsb pdb:4A5K|rcsb pdb:4A6F|rcsb pdb:4A6H|rcsb pdb:4A6K psi-mi:"MI:0469"(intact) - crc64:849C82CC0960014B figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oTFsdtOngA3q5wCbhK/fpVlIsz0559292 rogid:f0Gtntpff7Oav37jlVaggG2VI30559292 intact-crc:65ADBB8431A9355A|rigid:IyW2iYPMUtsfodzKGeUBueu3mm4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P40485 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-25172|uniprotkb:D6VVI2|ensemblfungi:YIL105C psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:slm1_yeast(display_long)|uniprotkb:TORC2 effector protein SLM1(gene name synonym)|uniprotkb:Synthetic lethal with MSS4 protein 1(gene name synonym)|uniprotkb:YIL105C(locus name)|uniprotkb:SLM1(gene name)|psi-mi:SLM1(display_short)|uniprotkb:LIT2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332484|imex:IM-14275-1687 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 refseq:NP_012161.1|sgd:S000001367|mint:P40485|dip:DIP-1353N|ensemblfungi:YIL105C(gene)|ensemblfungi:YIL105C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070941"(eisosome assembly)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR033191|interpro:IPR043453|rcsb pdb:3NSU|rcsb pdb:4A5K|rcsb pdb:4A6F|rcsb pdb:4A6H|rcsb pdb:4A6K psi-mi:"MI:0469"(intact) - crc64:849C82CC0960014B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:f0Gtntpff7Oav37jlVaggG2VI30559292 intact-crc:42587909B7CB4BE3|rigid:NXjkL8sFEBaIEzi4e4cy5X40IIQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:P40485 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-25172|uniprotkb:D6VVI2|ensemblfungi:YIL105C psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:slm1_yeast(display_long)|uniprotkb:TORC2 effector protein SLM1(gene name synonym)|uniprotkb:Synthetic lethal with MSS4 protein 1(gene name synonym)|uniprotkb:YIL105C(locus name)|uniprotkb:SLM1(gene name)|psi-mi:SLM1(display_short)|uniprotkb:LIT2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332495|imex:IM-14275-1688 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N refseq:NP_012161.1|sgd:S000001367|mint:P40485|dip:DIP-1353N|ensemblfungi:YIL105C(gene)|ensemblfungi:YIL105C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070941"(eisosome assembly)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR033191|interpro:IPR043453|rcsb pdb:3NSU|rcsb pdb:4A5K|rcsb pdb:4A6F|rcsb pdb:4A6H|rcsb pdb:4A6K psi-mi:"MI:0469"(intact) - crc64:849C82CC0960014B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:f0Gtntpff7Oav37jlVaggG2VI30559292 intact-crc:41B66FA3C99A3D54|rigid:y3SWG+m/qLIffzXDtssUel4dV3o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40485 uniprotkb:P38234 intact:EBI-25172|uniprotkb:D6VVI2|ensemblfungi:YIL105C intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C psi-mi:slm1_yeast(display_long)|uniprotkb:TORC2 effector protein SLM1(gene name synonym)|uniprotkb:Synthetic lethal with MSS4 protein 1(gene name synonym)|uniprotkb:YIL105C(locus name)|uniprotkb:SLM1(gene name)|psi-mi:SLM1(display_short)|uniprotkb:LIT2(gene name synonym) psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332506|imex:IM-14275-1689 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012161.1|sgd:S000001367|mint:P40485|dip:DIP-1353N|ensemblfungi:YIL105C(gene)|ensemblfungi:YIL105C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070941"(eisosome assembly)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR033191|interpro:IPR043453|rcsb pdb:3NSU|rcsb pdb:4A5K|rcsb pdb:4A6F|rcsb pdb:4A6H|rcsb pdb:4A6K refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 psi-mi:"MI:0469"(intact) crc64:849C82CC0960014B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:f0Gtntpff7Oav37jlVaggG2VI30559292 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 intact-crc:A3F8B5E00AA4A89D|rigid:ijq8SWIprFJPRZVMRS0CQr8k7qU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40485 uniprotkb:P40485 intact:EBI-25172|uniprotkb:D6VVI2|ensemblfungi:YIL105C intact:EBI-25172|uniprotkb:D6VVI2|ensemblfungi:YIL105C psi-mi:slm1_yeast(display_long)|uniprotkb:TORC2 effector protein SLM1(gene name synonym)|uniprotkb:Synthetic lethal with MSS4 protein 1(gene name synonym)|uniprotkb:YIL105C(locus name)|uniprotkb:SLM1(gene name)|psi-mi:SLM1(display_short)|uniprotkb:LIT2(gene name synonym) psi-mi:slm1_yeast(display_long)|uniprotkb:TORC2 effector protein SLM1(gene name synonym)|uniprotkb:Synthetic lethal with MSS4 protein 1(gene name synonym)|uniprotkb:YIL105C(locus name)|uniprotkb:SLM1(gene name)|psi-mi:SLM1(display_short)|uniprotkb:LIT2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332517|imex:IM-14275-1690 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012161.1|sgd:S000001367|mint:P40485|dip:DIP-1353N|ensemblfungi:YIL105C(gene)|ensemblfungi:YIL105C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070941"(eisosome assembly)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR033191|interpro:IPR043453|rcsb pdb:3NSU|rcsb pdb:4A5K|rcsb pdb:4A6F|rcsb pdb:4A6H|rcsb pdb:4A6K refseq:NP_012161.1|sgd:S000001367|mint:P40485|dip:DIP-1353N|ensemblfungi:YIL105C(gene)|ensemblfungi:YIL105C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070941"(eisosome assembly)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR033191|interpro:IPR043453|rcsb pdb:3NSU|rcsb pdb:4A5K|rcsb pdb:4A6F|rcsb pdb:4A6H|rcsb pdb:4A6K psi-mi:"MI:0469"(intact) crc64:849C82CC0960014B crc64:849C82CC0960014B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:f0Gtntpff7Oav37jlVaggG2VI30559292 rogid:f0Gtntpff7Oav37jlVaggG2VI30559292 intact-crc:6E378A58A687E8DA|rigid://ESHpGgx+QDPkROL4a34FWFETQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P40485 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-25172|uniprotkb:D6VVI2|ensemblfungi:YIL105C psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:slm1_yeast(display_long)|uniprotkb:TORC2 effector protein SLM1(gene name synonym)|uniprotkb:Synthetic lethal with MSS4 protein 1(gene name synonym)|uniprotkb:YIL105C(locus name)|uniprotkb:SLM1(gene name)|psi-mi:SLM1(display_short)|uniprotkb:LIT2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332528|imex:IM-14275-1691 author score:99.26 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_012161.1|sgd:S000001367|mint:P40485|dip:DIP-1353N|ensemblfungi:YIL105C(gene)|ensemblfungi:YIL105C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070941"(eisosome assembly)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR033191|interpro:IPR043453|rcsb pdb:3NSU|rcsb pdb:4A5K|rcsb pdb:4A6F|rcsb pdb:4A6H|rcsb pdb:4A6K psi-mi:"MI:0469"(intact) - crc64:849C82CC0960014B figure legend:tables S3 and S4|author-confidence:99.26|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:f0Gtntpff7Oav37jlVaggG2VI30559292 intact-crc:F092ADFD6E20B251|rigid:NVw19uGZ0CE/caTdFE4BjmZG/BE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53278 uniprotkb:P40485 intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C intact:EBI-25172|uniprotkb:D6VVI2|ensemblfungi:YIL105C psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name) psi-mi:slm1_yeast(display_long)|uniprotkb:TORC2 effector protein SLM1(gene name synonym)|uniprotkb:Synthetic lethal with MSS4 protein 1(gene name synonym)|uniprotkb:YIL105C(locus name)|uniprotkb:SLM1(gene name)|psi-mi:SLM1(display_short)|uniprotkb:LIT2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332539|imex:IM-14275-1692 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome) refseq:NP_012161.1|sgd:S000001367|mint:P40485|dip:DIP-1353N|ensemblfungi:YIL105C(gene)|ensemblfungi:YIL105C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070941"(eisosome assembly)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR033191|interpro:IPR043453|rcsb pdb:3NSU|rcsb pdb:4A5K|rcsb pdb:4A6F|rcsb pdb:4A6H|rcsb pdb:4A6K psi-mi:"MI:0469"(intact) crc64:D482327C9274C026 crc64:849C82CC0960014B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292 rogid:f0Gtntpff7Oav37jlVaggG2VI30559292 intact-crc:2C089E9856A6EF62|rigid:3R5Dsl0dsO+bG/iTg0DMD0SAZ34 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53283 uniprotkb:P40485 intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C intact:EBI-25172|uniprotkb:D6VVI2|ensemblfungi:YIL105C psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:slm1_yeast(display_long)|uniprotkb:TORC2 effector protein SLM1(gene name synonym)|uniprotkb:Synthetic lethal with MSS4 protein 1(gene name synonym)|uniprotkb:YIL105C(locus name)|uniprotkb:SLM1(gene name)|psi-mi:SLM1(display_short)|uniprotkb:LIT2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332550|imex:IM-14275-1693 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_012161.1|sgd:S000001367|mint:P40485|dip:DIP-1353N|ensemblfungi:YIL105C(gene)|ensemblfungi:YIL105C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070941"(eisosome assembly)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR033191|interpro:IPR043453|rcsb pdb:3NSU|rcsb pdb:4A5K|rcsb pdb:4A6F|rcsb pdb:4A6H|rcsb pdb:4A6K psi-mi:"MI:0469"(intact) - crc64:849C82CC0960014B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 rogid:f0Gtntpff7Oav37jlVaggG2VI30559292 intact-crc:DD683DABD4CE9051|rigid:z33dqihOPo7LOnpaE8BU8sQwh5U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40485 uniprotkb:Q02785 intact:EBI-25172|uniprotkb:D6VVI2|ensemblfungi:YIL105C intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:slm1_yeast(display_long)|uniprotkb:TORC2 effector protein SLM1(gene name synonym)|uniprotkb:Synthetic lethal with MSS4 protein 1(gene name synonym)|uniprotkb:YIL105C(locus name)|uniprotkb:SLM1(gene name)|psi-mi:SLM1(display_short)|uniprotkb:LIT2(gene name synonym) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332561|imex:IM-14275-1694 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012161.1|sgd:S000001367|mint:P40485|dip:DIP-1353N|ensemblfungi:YIL105C(gene)|ensemblfungi:YIL105C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070941"(eisosome assembly)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR033191|interpro:IPR043453|rcsb pdb:3NSU|rcsb pdb:4A5K|rcsb pdb:4A6F|rcsb pdb:4A6H|rcsb pdb:4A6K refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) crc64:849C82CC0960014B - figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:f0Gtntpff7Oav37jlVaggG2VI30559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:94931DA6EE605F1E|rigid:civpQf5ipwMVjP5Jb2fTJ/ODsL8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P40485 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-25172|uniprotkb:D6VVI2|ensemblfungi:YIL105C psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:slm1_yeast(display_long)|uniprotkb:TORC2 effector protein SLM1(gene name synonym)|uniprotkb:Synthetic lethal with MSS4 protein 1(gene name synonym)|uniprotkb:YIL105C(locus name)|uniprotkb:SLM1(gene name)|psi-mi:SLM1(display_short)|uniprotkb:LIT2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332572|imex:IM-14275-1695 author score:99.26 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_012161.1|sgd:S000001367|mint:P40485|dip:DIP-1353N|ensemblfungi:YIL105C(gene)|ensemblfungi:YIL105C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070941"(eisosome assembly)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR033191|interpro:IPR043453|rcsb pdb:3NSU|rcsb pdb:4A5K|rcsb pdb:4A6F|rcsb pdb:4A6H|rcsb pdb:4A6K psi-mi:"MI:0469"(intact) - crc64:849C82CC0960014B figure legend:tables S3 and S4|author-confidence:99.26|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:f0Gtntpff7Oav37jlVaggG2VI30559292 intact-crc:9ABB8BC8A80D3ADE|rigid:TYT+R5zt74sgZMtVgGgfPzHeLW4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40485 uniprotkb:Q12335 intact:EBI-25172|uniprotkb:D6VVI2|ensemblfungi:YIL105C intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:slm1_yeast(display_long)|uniprotkb:TORC2 effector protein SLM1(gene name synonym)|uniprotkb:Synthetic lethal with MSS4 protein 1(gene name synonym)|uniprotkb:YIL105C(locus name)|uniprotkb:SLM1(gene name)|psi-mi:SLM1(display_short)|uniprotkb:LIT2(gene name synonym) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332583|imex:IM-14275-1696 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012161.1|sgd:S000001367|mint:P40485|dip:DIP-1353N|ensemblfungi:YIL105C(gene)|ensemblfungi:YIL105C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070941"(eisosome assembly)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR033191|interpro:IPR043453|rcsb pdb:3NSU|rcsb pdb:4A5K|rcsb pdb:4A6F|rcsb pdb:4A6H|rcsb pdb:4A6K refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) crc64:849C82CC0960014B crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:f0Gtntpff7Oav37jlVaggG2VI30559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:91221AF7CE207DF9|rigid:Q5zLwlY36gffsnQZIacFTOKtf14 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38328 uniprotkb:P40494 intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C intact:EBI-9703|uniprotkb:Q02553|ensemblfungi:YIL095W|uniprotkb:D6VVJ2 psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:prk1_yeast(display_long)|uniprotkb:PAK1(gene name synonym)|uniprotkb:YIL095W(locus name)|uniprotkb:PRK1(gene name)|psi-mi:PRK1(display_short)|uniprotkb:p53-regulating kinase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332594|imex:IM-14275-1697 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|reactome:R-SCE-8856828|go:"GO:0106311"|go:"GO:0120133"(negative regulation of actin cortical patch assembly)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|ensemblfungi:YIL095W(gene)|ensemblfungi:YIL095W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|refseq:NP_012171.1|sgd:S000001357|mint:P40494|dip:DIP-6271N psi-mi:"MI:0469"(intact) crc64:D75C6BB8EC35EEDF crc64:AF710F930B39BC7E figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 rogid:Etg7IBo3vx49huiVMgmNjDDSoVo559292 intact-crc:E09066FA13E6656E|rigid:WRJt8B6D24ZJR80yPulUBf8HhhQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04217 uniprotkb:P40504 intact:EBI-1820|ensemblfungi:YMR128W|uniprotkb:D6VZV1 intact:EBI-10011|uniprotkb:D6VVK1|ensemblfungi:YIL085C psi-mi:dhr1_yeast(display_long)|uniprotkb:ECM16(gene name)|psi-mi:ECM16(display_short)|uniprotkb:DHR1(gene name synonym)|uniprotkb:YMR128W(locus name)|uniprotkb:YM9553.04(orf name)|uniprotkb:DEAH box RNA helicase DHR1(gene name synonym)|uniprotkb:Extracellular mutant protein 16(gene name synonym) psi-mi:ktr7_yeast(display_long)|uniprotkb:YIL085C(locus name)|uniprotkb:KTR7(gene name)|psi-mi:KTR7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332605|imex:IM-14275-1698 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR128W(gene)|ensemblfungi:YMR128W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|rcsb pdb:6H57|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_013847.1|sgd:S000004735|dip:DIP-6722N|mint:Q04217 sgd:S000001347|ensemblfungi:YIL085C(gene)|ensemblfungi:YIL085C_mRNA(transcript)|go:"GO:0000026"(alpha-1,2-mannosyltransferase activity)|go:"GO:0000030"(mannosyltransferase activity)|go:"GO:0000032"(cell wall mannoprotein biosynthetic process)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0097502"(mannosylation)|interpro:IPR002685(Glycosyl transferase, family 15)|interpro:IPR029044|refseq:NP_012181.3|dip:DIP-4677N|mint:P40504 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UN6v3h4OiKlKuYfkyy/fHqmkri8559292 rogid:8DaQMuwPKVBrmw3+qQze25NU0do559292 intact-crc:4732688093B03A1B|rigid:PBNZ5nt8s4uMFSbAUWw3wGAo77I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40513 uniprotkb:P19807 intact:EBI-10316|uniprotkb:Q6Q5P4|ensemblfungi:YIL070C|uniprotkb:D6VVL4 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:mam33_yeast(display_long)|uniprotkb:MAM33(gene name)|psi-mi:MAM33(display_short)|uniprotkb:YIL070C(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332616|imex:IM-14275-1699 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012194.1|sgd:S000001332|ensemblfungi:YIL070C(gene)|reactome:R-SCE-8980692|ensemblfungi:YIL070C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0008494"(translation activator activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0097177"(mitochondrial ribosome binding)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|rcsb pdb:3QV0|dip:DIP-4925N|mint:P40513 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) crc64:C4D5B0D761104366 - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Es0RjUIH4+euspGNBxSSjZGNmGo559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:4C1E7BBDC2D0A9DA|rigid:RREgPIJ/wqZNr4KfkZ4/WHmmEc8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P40513 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-10316|uniprotkb:Q6Q5P4|ensemblfungi:YIL070C|uniprotkb:D6VVL4 psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:mam33_yeast(display_long)|uniprotkb:MAM33(gene name)|psi-mi:MAM33(display_short)|uniprotkb:YIL070C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332627|imex:IM-14275-1700 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 refseq:NP_012194.1|sgd:S000001332|ensemblfungi:YIL070C(gene)|reactome:R-SCE-8980692|ensemblfungi:YIL070C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0008494"(translation activator activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0097177"(mitochondrial ribosome binding)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|rcsb pdb:3QV0|dip:DIP-4925N|mint:P40513 psi-mi:"MI:0469"(intact) - crc64:C4D5B0D761104366 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:Es0RjUIH4+euspGNBxSSjZGNmGo559292 intact-crc:873D6D3677DEFD41|rigid:VQcJKSBo7XSQa2gGBU3KF8eAdH8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:P40513 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-10316|uniprotkb:Q6Q5P4|ensemblfungi:YIL070C|uniprotkb:D6VVL4 psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:mam33_yeast(display_long)|uniprotkb:MAM33(gene name)|psi-mi:MAM33(display_short)|uniprotkb:YIL070C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332638|imex:IM-14275-1701 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N refseq:NP_012194.1|sgd:S000001332|ensemblfungi:YIL070C(gene)|reactome:R-SCE-8980692|ensemblfungi:YIL070C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0008494"(translation activator activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0097177"(mitochondrial ribosome binding)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|rcsb pdb:3QV0|dip:DIP-4925N|mint:P40513 psi-mi:"MI:0469"(intact) - crc64:C4D5B0D761104366 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:Es0RjUIH4+euspGNBxSSjZGNmGo559292 intact-crc:84D3794C098F8BF6|rigid:1rqklYLluYcAkjlnu4lpQ9rfkNw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40513 uniprotkb:P38234 intact:EBI-10316|uniprotkb:Q6Q5P4|ensemblfungi:YIL070C|uniprotkb:D6VVL4 intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C psi-mi:mam33_yeast(display_long)|uniprotkb:MAM33(gene name)|psi-mi:MAM33(display_short)|uniprotkb:YIL070C(locus name) psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332649|imex:IM-14275-1702 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012194.1|sgd:S000001332|ensemblfungi:YIL070C(gene)|reactome:R-SCE-8980692|ensemblfungi:YIL070C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0008494"(translation activator activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0097177"(mitochondrial ribosome binding)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|rcsb pdb:3QV0|dip:DIP-4925N|mint:P40513 refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 psi-mi:"MI:0469"(intact) crc64:C4D5B0D761104366 - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Es0RjUIH4+euspGNBxSSjZGNmGo559292 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 intact-crc:669DA30FCAB11E3F|rigid:zWc3nb0G50i8aNeWYOwd4mNeacM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40485 uniprotkb:P40513 intact:EBI-25172|uniprotkb:D6VVI2|ensemblfungi:YIL105C intact:EBI-10316|uniprotkb:Q6Q5P4|ensemblfungi:YIL070C|uniprotkb:D6VVL4 psi-mi:slm1_yeast(display_long)|uniprotkb:TORC2 effector protein SLM1(gene name synonym)|uniprotkb:Synthetic lethal with MSS4 protein 1(gene name synonym)|uniprotkb:YIL105C(locus name)|uniprotkb:SLM1(gene name)|psi-mi:SLM1(display_short)|uniprotkb:LIT2(gene name synonym) psi-mi:mam33_yeast(display_long)|uniprotkb:MAM33(gene name)|psi-mi:MAM33(display_short)|uniprotkb:YIL070C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332660|imex:IM-14275-1703 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012161.1|sgd:S000001367|mint:P40485|dip:DIP-1353N|ensemblfungi:YIL105C(gene)|ensemblfungi:YIL105C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070941"(eisosome assembly)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR033191|interpro:IPR043453|rcsb pdb:3NSU|rcsb pdb:4A5K|rcsb pdb:4A6F|rcsb pdb:4A6H|rcsb pdb:4A6K refseq:NP_012194.1|sgd:S000001332|ensemblfungi:YIL070C(gene)|reactome:R-SCE-8980692|ensemblfungi:YIL070C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0008494"(translation activator activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0097177"(mitochondrial ribosome binding)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|rcsb pdb:3QV0|dip:DIP-4925N|mint:P40513 psi-mi:"MI:0469"(intact) crc64:849C82CC0960014B crc64:C4D5B0D761104366 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:f0Gtntpff7Oav37jlVaggG2VI30559292 rogid:Es0RjUIH4+euspGNBxSSjZGNmGo559292 intact-crc:2A93668F78FF6AF6|rigid:OhQsBoyC4k1wmwMHIQiuSsYUlqo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12335 uniprotkb:P40513 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 intact:EBI-10316|uniprotkb:Q6Q5P4|ensemblfungi:YIL070C|uniprotkb:D6VVL4 psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:mam33_yeast(display_long)|uniprotkb:MAM33(gene name)|psi-mi:MAM33(display_short)|uniprotkb:YIL070C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332671|imex:IM-14275-1704 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N refseq:NP_012194.1|sgd:S000001332|ensemblfungi:YIL070C(gene)|reactome:R-SCE-8980692|ensemblfungi:YIL070C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0008494"(translation activator activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0097177"(mitochondrial ribosome binding)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|rcsb pdb:3QV0|dip:DIP-4925N|mint:P40513 psi-mi:"MI:0469"(intact) crc64:1056E7A1F3E82288 crc64:C4D5B0D761104366 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 rogid:Es0RjUIH4+euspGNBxSSjZGNmGo559292 intact-crc:2DA9FA5C60672456|rigid:Wm88tgW/NWnAjKKXg2n+DanH7HU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38310 uniprotkb:P40528 intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W intact:EBI-18696|uniprotkb:P40964|uniprotkb:D6VVN4|ensemblfungi:YIL047C psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:syg1_yeast(display_long)|uniprotkb:SYG1(gene name)|psi-mi:SYG1(display_short)|uniprotkb:YIL047C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332682|imex:IM-14275-1705 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) sgd:S000001309|ensemblfungi:YIL047C(gene)|ensemblfungi:YIL047C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0007165"(signal transduction)|go:"GO:0015114"(phosphate ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016036"(cellular response to phosphate starvation)|interpro:IPR004331(SPX, N-terminal)|interpro:IPR004342(EXS, C-terminal)|interpro:IPR033507|refseq:NP_012217.3|dip:DIP-2383N|mint:P40528 psi-mi:"MI:0469"(intact) crc64:7B4E620ABC39A053 - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 rogid:smo53yPo0x4OU9yUG8L0t0awiBg559292 intact-crc:1C5ECCEB1DF93DC6|rigid:+JIkdLwQiicr831ihAfN6zeYyxg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40528 uniprotkb:P40528 intact:EBI-18696|uniprotkb:P40964|uniprotkb:D6VVN4|ensemblfungi:YIL047C intact:EBI-18696|uniprotkb:P40964|uniprotkb:D6VVN4|ensemblfungi:YIL047C psi-mi:syg1_yeast(display_long)|uniprotkb:SYG1(gene name)|psi-mi:SYG1(display_short)|uniprotkb:YIL047C(locus name) psi-mi:syg1_yeast(display_long)|uniprotkb:SYG1(gene name)|psi-mi:SYG1(display_short)|uniprotkb:YIL047C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332693|imex:IM-14275-1706 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001309|ensemblfungi:YIL047C(gene)|ensemblfungi:YIL047C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0007165"(signal transduction)|go:"GO:0015114"(phosphate ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016036"(cellular response to phosphate starvation)|interpro:IPR004331(SPX, N-terminal)|interpro:IPR004342(EXS, C-terminal)|interpro:IPR033507|refseq:NP_012217.3|dip:DIP-2383N|mint:P40528 sgd:S000001309|ensemblfungi:YIL047C(gene)|ensemblfungi:YIL047C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0007165"(signal transduction)|go:"GO:0015114"(phosphate ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016036"(cellular response to phosphate starvation)|interpro:IPR004331(SPX, N-terminal)|interpro:IPR004342(EXS, C-terminal)|interpro:IPR033507|refseq:NP_012217.3|dip:DIP-2383N|mint:P40528 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:smo53yPo0x4OU9yUG8L0t0awiBg559292 rogid:smo53yPo0x4OU9yUG8L0t0awiBg559292 intact-crc:C3947012C284EB11|rigid:yAwbV8w86wGmyc4AVf2vek0pNbM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40529 uniprotkb:P22137 intact:EBI-25014|uniprotkb:D6VVN8|ensemblfungi:YIL044C intact:EBI-4766|uniprotkb:D6VTU9|ensemblfungi:YGL206C psi-mi:age2_yeast(display_long)|uniprotkb:AGE2(gene name)|psi-mi:AGE2(display_short)|uniprotkb:YIL044C(locus name) psi-mi:clh_yeast(display_long)|uniprotkb:CHC1(gene name)|psi-mi:CHC1(display_short)|uniprotkb:YGL206C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332704|imex:IM-14275-1707 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001306|refseq:NP_012220.3|mint:P40529|dip:DIP-5383N|ensemblfungi:YIL044C(gene)|ensemblfungi:YIL044C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0046872"(metal ion binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR037278|interpro:IPR038508 refseq:NP_011309.1|sgd:S000003174|dip:DIP-2279N|mint:P22137|ensemblfungi:YGL206C(gene)|ensemblfungi:YGL206C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0071439"(clathrin complex)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-432720|reactome:R-SCE-437239|reactome:R-SCE-8856828|reactome:R-SCE-8866427|reactome:R-SCE-8964038 psi-mi:"MI:0469"(intact) - crc64:622F3083DF2FE315 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:uHnQpbfunTgV9LOrDOt8hFI2zgk559292 rogid:SAN6H3nVFozXZyTiRLaljMcIKIA559292 intact-crc:AC41DD9762120F0A|rigid:FSXVnHnkeufDsj7aQmI3XI7YkKU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15496 uniprotkb:P40535 intact:EBI-8902|ensemblfungi:YPL117C|uniprotkb:D6W3Q1 intact:EBI-2052|uniprotkb:D6VVP6|ensemblfungi:YIL036W psi-mi:idi1_yeast(display_long)|uniprotkb:Isopentenyl pyrophosphate isomerase(gene name synonym)|uniprotkb:IDI1(gene name)|psi-mi:IDI1(display_short)|uniprotkb:BOT2(gene name synonym)|uniprotkb:YPL117C(locus name)|uniprotkb:LPH10C(orf name) psi-mi:aca2_yeast(display_long)|uniprotkb:CST6(gene name)|psi-mi:CST6(display_short)|uniprotkb:ACA2(gene name synonym)|uniprotkb:Chromosome stability protein CST6(gene name synonym)|uniprotkb:YIL036W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332715|imex:IM-14275-1708 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL117C(gene)|ensemblfungi:YPL117C_mRNA(transcript)|go:"GO:0004452"(isopentenyl-diphosphate delta-isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009240"(isopentenyl diphosphate biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0045337"(farnesyl diphosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050992"(dimethylallyl diphosphate biosynthetic process)|reactome:R-SCE-191273|refseq:NP_015208.1|sgd:S000006038|interpro:IPR011876(Isopentenyl-diphosphate delta-isomerase, type 1)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|mint:P15496 refseq:NP_012228.1|sgd:S000001298|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|mint:P40535|interpro:IPR029810|ensemblfungi:YIL036W(gene)|ensemblfungi:YIL036W_mRNA(transcript)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061429"(positive regulation of transcription from RNA polymerase II promoter by oleic acid)|go:"GO:0071244"(cellular response to carbon dioxide)|go:"GO:0071400"(cellular response to oleic acid)|reactome:R-SCE-3214847|reactome:R-SCE-450341 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:KQ9qSb2grQ4DQip7atYPeCwp5QM559292 rogid:RnF39Bd4e1jucOGY2R4w4aY9Za0559292 intact-crc:2E96AC57C69A80B0|rigid:NpqJSQ5Jp4Vzb4bYDfWXB/hA6N0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08518 uniprotkb:P40540 intact:EBI-15767|uniprotkb:Q12738|uniprotkb:Q7Z9Y0|uniprotkb:D6W2K8|ensemblfungi:YOR151C intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C psi-mi:rpb2_yeast(display_long)|uniprotkb:YOR151C(locus name)|uniprotkb:RPB2(gene name)|psi-mi:RPB2(display_short)|uniprotkb:RPB150(gene name synonym)|uniprotkb:RPO22(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym)|uniprotkb:B150(gene name synonym) psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332726|imex:IM-14275-1709 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005677|refseq:NP_014794.3|dip:DIP-14N|mint:P08518|ensemblfungi:YOR151C(gene)|ensemblfungi:YOR151C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519 refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) crc64:BABD03212C0A583E crc64:6DBEEEE7722203B0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:OtaUDREazRORKDcfBajDLPlXovY559292 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 intact-crc:A8FFC594AE50BBAC|rigid:3smPMBbiek1gQZchAJZ9x2FNDyE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CY06 uniprotkb:P40540 intact:EBI-10438|ensemblfungi:YCL066W|ensemblfungi:YCR040W|uniprotkb:D6VQV3|intact:EBI-6332742|uniprotkb:P01365 intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C psi-mi:mtal1_yeast(display_long)|uniprotkb:MATALPHA1(gene name)|psi-mi:MATALPHA1(display_short)|uniprotkb:ALPHA-1(gene name synonym)|uniprotkb:MAT1A(gene name synonym)|uniprotkb:MATAL1(gene name synonym)|uniprotkb:YCR040W(locus name)|uniprotkb:YCR40W(orf name)|uniprotkb:Alpha-1 activator(gene name synonym) psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332737|imex:IM-14275-1710 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCL066W(gene)|ensemblfungi:YCL066W_mRNA(transcript)|ensemblfungi:YCR040W(gene)|ensemblfungi:YCR040W_mRNA(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007532"(regulation of mating-type specific transcription, DNA-templated)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0045895"(positive regulation of mating-type specific transcription, DNA-templated)|interpro:IPR006856(Mating-type protein MAT alpha 1)|sgd:S000000636|refseq:NP_009867.1|refseq:NP_009869.3|mint:P0CY06 refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) caution:This sequence has been withdrawn from Uniprot.|crc64:697199A7686D19C0 crc64:6DBEEEE7722203B0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2016/09/27 rogid:jtoBfRahpRzvTzy7h38B9/9xV70559292 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 intact-crc:C7216D51CF2D5D41|rigid:6sf+Yg8BC3FpGNYtbWA2JV2VMX4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P40540 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332750|imex:IM-14275-1711 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) - crc64:6DBEEEE7722203B0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 intact-crc:0784E344D177FAD1|rigid:qE7Jk91vPqy42x85B5hkH1UDtLI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:P40540 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332761|imex:IM-14275-1712 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) crc64:DBA26AF5B769C02A crc64:6DBEEEE7722203B0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 intact-crc:15A9BBF360C77D80|rigid:1K5OREYp9TOAKMa5YagN1YtiJJ8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40540 uniprotkb:P38264 intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332772|imex:IM-14275-1713 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N psi-mi:"MI:0469"(intact) crc64:6DBEEEE7722203B0 - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 intact-crc:109F62F20C57461C|rigid:EeZRxp2gNslcVglc6K3ABdZB78o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40540 uniprotkb:P38782 intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C intact:EBI-10667|ensemblfungi:YHR058C|uniprotkb:D3DL07 psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:med6_yeast(display_long)|uniprotkb:MTR32(gene name synonym)|uniprotkb:YHR058C(locus name)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332783|imex:IM-14275-1714 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX refseq:NP_011925.1|sgd:S000001100|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016612(Mediator complex, subunit 6, fungi)|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YHR058C(gene)|ensemblfungi:YHR058C_mRNA(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|mint:P38782|dip:DIP-2093N psi-mi:"MI:0469"(intact) crc64:6DBEEEE7722203B0 crc64:B84E87DCC2737849 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 rogid:XcKvvx/GJGRLZpv1MPzpPtVd2RI559292 intact-crc:4B8387E9BD30869C|rigid:gKat5tjkU3jLiYu5E3RpPcWLnSk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38902 uniprotkb:P40540 intact:EBI-15806|ensemblfungi:YOL005C|uniprotkb:D6W262 intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C psi-mi:rpb11_yeast(display_long)|uniprotkb:YOL005C(locus name)|uniprotkb:RPB11(gene name)|psi-mi:RPB11(display_short)|uniprotkb:DNA-directed RNA polymerase II 13.6 kDa polypeptide(gene name synonym)|uniprotkb:B13.6(gene name synonym) psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332794|imex:IM-14275-1715 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014638.1|sgd:S000005365|ensemblfungi:YOL005C_mRNA(transcript)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR036603|interpro:IPR037685|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|ensemblfungi:YOL005C(gene)|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:4A93|rcsb pdb:5SVA|rcsb pdb:4BBR|rcsb pdb:5U5Q|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4V1M|rcsb pdb:6BLP|rcsb pdb:6UQ3|rcsb pdb:6BM2|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:7KEF|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|dip:DIP-937N|mint:P38902 refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) crc64:A98D109C5FF8E356 crc64:6DBEEEE7722203B0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:C9ofD255l4o5MjuGiqUVPfY4FdQ559292 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 intact-crc:919E4A8998E52E87|rigid:qjXzn4A/19eINqxDHd6Pf2epNo8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39543 uniprotkb:P40540 intact:EBI-26193|uniprotkb:D6VVZ9|ensemblfungi:YJL192C intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C psi-mi:sop4_yeast(display_long)|uniprotkb:Suppressor of PMA1-7 protein 4(gene name synonym)|uniprotkb:YJL192C(locus name)|uniprotkb:J0351(orf name)|uniprotkb:SOP4(gene name)|psi-mi:SOP4(display_short) psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332805|imex:IM-14275-1716 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003728|refseq:NP_012343.1|mint:P39543|dip:DIP-5094N|ensemblfungi:YJL192C(gene)|ensemblfungi:YJL192C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR031395|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) - crc64:6DBEEEE7722203B0 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:a+WulVpSm4gdxpcINNvDPLR2rZI559292 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 intact-crc:3C222B3C375E4A33|rigid:5u9NQ+s+mPAd1P4FNHZnHkUFzGE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40540 uniprotkb:P40540 intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332816|imex:IM-14275-1717 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) crc64:6DBEEEE7722203B0 crc64:6DBEEEE7722203B0 figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 intact-crc:62D8DB2CC809F732|rigid:lKiJpZZ4RRoriZj6L2xyIEltIis false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47006 uniprotkb:P40540 intact:EBI-26109|uniprotkb:D6VW37|ensemblfungi:YJL148W intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C psi-mi:rpa34_yeast(display_long)|uniprotkb:YJL148W(locus name)|uniprotkb:J0637(orf name)|uniprotkb:RPA34(gene name)|psi-mi:RPA34(display_short)|uniprotkb:DNA-directed DNA-dependent RNA polymerase 34.5 kDa polypeptide(gene name synonym) psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332827|imex:IM-14275-1718 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012387.1|sgd:S000003684|mint:P47006|dip:DIP-7973N|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|ensemblfungi:YJL148W(gene)|ensemblfungi:YJL148W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR013240(RNA polymerase I, subunit RPA34.5, fungi)|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61 refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) crc64:DCD42DFEC574EDB6 crc64:6DBEEEE7722203B0 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:KCG3Ws8+82TSLsqPB7bedHq/JEI559292 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 intact-crc:BA1A44D78598A36D|rigid:I5iyBTNjQzWnpyJXCJo6fagJRhc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02785 uniprotkb:P40540 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332838|imex:IM-14275-1719 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) - crc64:6DBEEEE7722203B0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 intact-crc:49F6BBC099C5318E|rigid:CWMyIxBugkaGUjDTofnwOi98rxo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40540 uniprotkb:Q02866 intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C intact:EBI-32646|uniprotkb:D6W3U5|ensemblfungi:YPL070W psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:muk1_yeast(display_long)|uniprotkb:MUK1(gene name)|psi-mi:MUK1(display_short)|uniprotkb:YPL070W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332849|imex:IM-14275-1720 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX refseq:NP_015255.1|sgd:S000005991|dip:DIP-1326N|mint:Q02866|ensemblfungi:YPL070W(gene)|ensemblfungi:YPL070W_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036010"(protein localization to endosome)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR037191|reactome:R-SCE-8856828|reactome:R-SCE-8876198 psi-mi:"MI:0469"(intact) crc64:6DBEEEE7722203B0 crc64:C743D0436E541978 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 rogid:1zJ9LpKI/gWKg35tna7E7DhjQ6w559292 intact-crc:723D9B2E7AE99E2B|rigid:jFec8piGG3Fw8OmM1v2Q4AqW7KY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40540 uniprotkb:Q03860 intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332860|imex:IM-14275-1721 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) crc64:6DBEEEE7722203B0 crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:CC14F0A51FDB7DF4|rigid:ntFS+mOcLL9RVpYrnnwLLCFDNfA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40540 uniprotkb:Q04377 intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C intact:EBI-35652|uniprotkb:D6VTC1|ensemblfungi:YDR499W psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:lcd1_yeast(display_long)|uniprotkb:LCD1(gene name)|psi-mi:LCD1(display_short)|uniprotkb:Lethal, checkpoint-defective, DNA damage-sensitive protein 1(gene name synonym)|uniprotkb:DNA damage checkpoint protein 2(gene name synonym)|uniprotkb:YDR499W(locus name)|uniprotkb:DDC2(gene name synonym)|uniprotkb:PIE1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332871|imex:IM-14275-1722 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX refseq:NP_010787.3|sgd:S000002907|mint:Q04377|dip:DIP-2970N|ensemblfungi:YDR499W(gene)|ensemblfungi:YDR499W_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0045184"(establishment of protein localization)|interpro:IPR018622|rcsb pdb:5OMD|rcsb pdb:5X6O|rcsb pdb:6Z2W|rcsb pdb:6Z2X|rcsb pdb:6Z3A psi-mi:"MI:0469"(intact) crc64:6DBEEEE7722203B0 crc64:E981C1A38F3310BF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 rogid:qx0fM2HHwEI/GtbjRXu8kQrSp5w559292 intact-crc:A621D3C1AB59A143|rigid:tJwawlJTsxRhj9UuCac7VlMYZjM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40540 uniprotkb:Q05359 intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332882|imex:IM-14275-1723 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:6DBEEEE7722203B0 - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 intact-crc:177E21BDAD825887|rigid:igsaFeOzsWup3/Vbfhd5UoddArE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40540 uniprotkb:Q06144 intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332893|imex:IM-14275-1724 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) crc64:6DBEEEE7722203B0 crc64:2F474503CAB7C195 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 intact-crc:54DB9B1BCB7158FF|rigid:qfPboMgL04ajXyEmHQOirlmrzqM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06408 uniprotkb:P40540 intact:EBI-32807|uniprotkb:D6VT13|ensemblfungi:YDR380W intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C psi-mi:aro10_yeast(display_long)|uniprotkb:ARO10(gene name)|psi-mi:ARO10(display_short)|uniprotkb:YDR380W(locus name)|uniprotkb:D9481.3(orf name)|uniprotkb:Transaminated branched-chain amino acid decarboxylase(gene name synonym)|uniprotkb:Thiamine diphosphate-dependent phenylpyruvate decarboxylase(gene name synonym)|uniprotkb:Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase(gene name synonym) psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332904|imex:IM-14275-1725 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002788|refseq:NP_010668.3|dip:DIP-5252N|mint:Q06408|ensemblfungi:YDR380W(gene)|ensemblfungi:YDR380W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000949"(aromatic amino acid family catabolic process to alcohol via Ehrlich pathway)|go:"GO:0000950"(branched-chain amino acid catabolic process to alcohol via Ehrlich pathway)|go:"GO:0000951"(methionine catabolic process to 3-methylthiopropanol)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0006559"(L-phenylalanine catabolic process)|go:"GO:0006569"(tryptophan catabolic process)|go:"GO:0006572"(tyrosine catabolic process)|go:"GO:0016831"(carboxy-lyase activity)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0047433"(branched-chain-2-oxoacid decarboxylase activity)|go:"GO:0047434"(indolepyruvate decarboxylase activity)|go:"GO:0050177"(phenylpyruvate decarboxylase activity)|go:"GO:0050546"(4-hydroxyphenylpyruvate decarboxylase activity)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR012110(Pyruvate decarboxylase/indolepyruvate decarboxylase)|interpro:IPR029035|interpro:IPR029061 refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) crc64:616DF7E06DA82415 crc64:6DBEEEE7722203B0 figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jh443SvRXK8vb+GUjPq95NB8jdU559292 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 intact-crc:50966FD3C40BB057|rigid:D+t69SwSY9sqOG3sPBFTGcqfboU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99278 uniprotkb:P40540 intact:EBI-27213|uniprotkb:D6VZT5 intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C psi-mi:med11_yeast(display_long)|uniprotkb:YMR112C(locus name)|uniprotkb:YM9718.11C(orf name)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short) psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332915|imex:IM-14275-1726 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004718|refseq:NP_013830.1|mint:Q99278|dip:DIP-1434N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019404|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) crc64:457D13C6030F33CC crc64:6DBEEEE7722203B0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjet29QRORdS5zMRJK/4/KtEF6E559292 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 intact-crc:58BD3FBC411F3034|rigid:f9zcglPduqA4WMVrBYPvD9+t1IE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3E806 uniprotkb:P40559 intact:EBI-2067801|uniprotkb:D6W315|ensemblfungi:YOR316C-A intact:EBI-24915|uniprotkb:D6VVS9|ensemblfungi:YIL002C psi-mi:yo316_yeast(display_long)|uniprotkb:YOR316C-A(locus name) psi-mi:inp51_yeast(display_long)|uniprotkb:YIL002C(locus name)|uniprotkb:YIA2C(orf name)|uniprotkb:INP51(gene name)|psi-mi:INP51(display_short)|uniprotkb:SJL1(gene name synonym)|uniprotkb:Synaptojanin-like protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332926|imex:IM-14275-1727 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000028584|refseq:NP_878175.1|mint:Q3E806|ensemblfungi:YOR316C-A(gene)|ensemblfungi:YOR316C-A_mRNA(transcript) sgd:S000001264|refseq:NP_012264.3|mint:P40559|dip:DIP-2677N|ensemblfungi:YIL002C(gene)|ensemblfungi:YIL002C_mRNA(transcript)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR002013(Synaptojanin, N-terminal)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|reactome:R-SCE-1660499|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TBdwRqQU2CRNBabtqjDmD/wMLBw559292 rogid:rIU7NYsMpt3GUXBf0jfAW7QyVxQ559292 intact-crc:1BB35C5DE00C8095|rigid:vV9/P4ysLMRiZ6sPNNeEWuvlmxI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25567 uniprotkb:P40561 intact:EBI-18084|uniprotkb:D6VQX8|ensemblfungi:YCL037C intact:EBI-25362|uniprotkb:D6VVT1|ensemblfungi:YIR001C psi-mi:sro9_yeast(display_long)|uniprotkb:SRO9(gene name)|psi-mi:SRO9(display_short)|uniprotkb:YCL037C(locus name)|uniprotkb:YCL37C(orf name)|uniprotkb:Suppressor of RHO3 protein 9(gene name synonym) psi-mi:sgn1_yeast(display_long)|uniprotkb:SGN1(gene name)|psi-mi:SGN1(display_short)|uniprotkb:RBP29(gene name synonym)|uniprotkb:YIR001C(locus name)|uniprotkb:YIB1C(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332937|imex:IM-14275-1728 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009893.2|sgd:S000000542|ensemblfungi:YCL037C(gene)|ensemblfungi:YCL037C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|dip:DIP-6638N|mint:P25567 refseq:NP_012266.1|sgd:S000001440|mint:P40561|dip:DIP-6566N|ensemblfungi:YIR001C(gene)|ensemblfungi:YIR001C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016071"(mRNA metabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979 psi-mi:"MI:0469"(intact) crc64:B1B720D40C7B9914 crc64:373908F72DEB6873 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CouwiBsK7S3Tm6CoBsu3LdWfelg559292 rogid:GbX9fnNU3PhF9FAa7V4XnppSbpA559292 intact-crc:5C5768ADC37D59F9|rigid:c1JUKx7fFUnHYsMuCLtVAeDXaGQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32588 uniprotkb:P40561 intact:EBI-14231|ensemblfungi:YNL016W|uniprotkb:D6W1G2 intact:EBI-25362|uniprotkb:D6VVT1|ensemblfungi:YIR001C psi-mi:pub1_yeast(display_long)|uniprotkb:ARS consensus-binding protein ACBP-60(gene name synonym)|uniprotkb:Poly uridylate-binding protein(gene name synonym)|uniprotkb:PUB1(gene name)|psi-mi:PUB1(display_short)|uniprotkb:RNP1(gene name synonym)|uniprotkb:YNL016W(locus name)|uniprotkb:N2842(orf name) psi-mi:sgn1_yeast(display_long)|uniprotkb:SGN1(gene name)|psi-mi:SGN1(display_short)|uniprotkb:RBP29(gene name synonym)|uniprotkb:YIR001C(locus name)|uniprotkb:YIB1C(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332948|imex:IM-14275-1729 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014382.1|sgd:S000004961|ensemblfungi:YNL016W(gene)|ensemblfungi:YNL016W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043488"(regulation of mRNA stability)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034509|interpro:IPR034639|interpro:IPR035979|rcsb pdb:2LA4|rcsb pdb:3MD1|rcsb pdb:3MD3|rcsb pdb:6Z29|mint:P32588|dip:DIP-5480N refseq:NP_012266.1|sgd:S000001440|mint:P40561|dip:DIP-6566N|ensemblfungi:YIR001C(gene)|ensemblfungi:YIR001C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016071"(mRNA metabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979 psi-mi:"MI:0469"(intact) crc64:3B81A7735505D3CA crc64:373908F72DEB6873 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8xFMuEva7leVYDKg3WOmvPtRTFk559292 rogid:GbX9fnNU3PhF9FAa7V4XnppSbpA559292 intact-crc:355C1A5F45B99482|rigid:Kt6JI33w+uJrzGBoXFrpVJMsuDs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53316 uniprotkb:P40561 intact:EBI-23586|uniprotkb:D6VV30|ensemblfungi:YGR250C intact:EBI-25362|uniprotkb:D6VVT1|ensemblfungi:YIR001C psi-mi:yg5b_yeast(display_long)|uniprotkb:YGR250C(locus name) psi-mi:sgn1_yeast(display_long)|uniprotkb:SGN1(gene name)|psi-mi:SGN1(display_short)|uniprotkb:RBP29(gene name synonym)|uniprotkb:YIR001C(locus name)|uniprotkb:YIB1C(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332959|imex:IM-14275-1730 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011766.3|sgd:S000003482|dip:DIP-5559N|mint:P53316|ensemblfungi:YGR250C(gene)|ensemblfungi:YGR250C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979 refseq:NP_012266.1|sgd:S000001440|mint:P40561|dip:DIP-6566N|ensemblfungi:YIR001C(gene)|ensemblfungi:YIR001C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016071"(mRNA metabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979 psi-mi:"MI:0469"(intact) crc64:C2CA1CBF5F6D395B crc64:373908F72DEB6873 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:PMluELxwVWyCMyMnmOBp0HyI604559292 rogid:GbX9fnNU3PhF9FAa7V4XnppSbpA559292 intact-crc:0A6755ECB141C1EC|rigid:ws4gZ+q5mE5SeJWQPvzcpya1euo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40016 uniprotkb:P40577 intact:EBI-15927|uniprotkb:D3DLS0|ensemblfungi:YER021W intact:EBI-25433|uniprotkb:D6VVV6|ensemblfungi:YIR025W psi-mi:rpn3_yeast(display_long)|uniprotkb:RPN3(gene name)|psi-mi:RPN3(display_short)|uniprotkb:SUN2(gene name synonym)|uniprotkb:YER021W(locus name) psi-mi:mnd2_yeast(display_long)|uniprotkb:YIR025W(locus name)|uniprotkb:MND2(gene name)|psi-mi:MND2(display_short)|uniprotkb:Meiotic nuclear division protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332970|imex:IM-14275-1731 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010938.1|sgd:S000000823|ensemblfungi:YER021W(gene)|ensemblfungi:YER021W_mRNA(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042176"(regulation of protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|dip:DIP-1322N|mint:P40016 refseq:NP_012291.1|sgd:S000001464|mint:P40577|dip:DIP-1536N|ensemblfungi:YIR025W(gene)|ensemblfungi:YIR025W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1905785"(negative regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR008402(Anaphase-promoting complex, Apc15p-like)|interpro:IPR016807(Anaphase promoting complex, MND2 subunit) psi-mi:"MI:0469"(intact) crc64:B08B58663DDA85DC crc64:D41276561E6ED509 figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pXkyoZKr0rI5usi19R+TvS4hSso559292 rogid:qyUgrmuBB0ZLxm8fxwos8Q4ijRI559292 intact-crc:3F613EE0DC8CC21A|rigid:T+Zk2PHF/fAzNb3ShgfFdGLXG/k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40581 uniprotkb:P0C268 intact:EBI-7869|ensemblfungi:YIR037W|uniprotkb:D6VVW8 intact:EBI-2044092|uniprotkb:D6VPV9|ensemblfungi:YBL039W-B psi-mi:gpx3_yeast(display_long)|uniprotkb:HYR1(gene name)|psi-mi:HYR1(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:Hydrogen peroxide resistance protein 1(gene name synonym)|uniprotkb:Oxidant receptor peroxidase 1(gene name synonym)|uniprotkb:Phospholipid hydroperoxide glutathione peroxidase 3(gene name synonym)|uniprotkb:GPX3(gene name synonym)|uniprotkb:YIR037W(locus name)|uniprotkb:Glutathione peroxidase homolog 3(gene name synonym) psi-mi:yb39b_yeast(display_long)|uniprotkb:YBL039W-B(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332981|imex:IM-14275-1732 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012303.1|sgd:S000001476|ensemblfungi:YIR037W(gene)|ensemblfungi:YIR037W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR029760|interpro:IPR036249|rcsb pdb:3CMI|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661|interpro:IPR029759|mint:P40581|dip:DIP-1275N sgd:S000028517|refseq:NP_878045.1|mint:P0C268|ensemblfungi:YBL039W-B(gene)|ensemblfungi:YBL039W-B_mRNA(transcript)|go:"GO:0005777"(peroxisome) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Pi8aaZEVc33CTMPyaM0mpscvLU4559292 rogid:EfowKSHyZ6Fgw3vWQ74mzPwXTbQ559292 intact-crc:55CFA13C3D308473|rigid:OxVZUpZDGbsu+b39KJ6Tk9TasTw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40581 uniprotkb:P10614 intact:EBI-7869|ensemblfungi:YIR037W|uniprotkb:D6VVW8 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:gpx3_yeast(display_long)|uniprotkb:HYR1(gene name)|psi-mi:HYR1(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:Hydrogen peroxide resistance protein 1(gene name synonym)|uniprotkb:Oxidant receptor peroxidase 1(gene name synonym)|uniprotkb:Phospholipid hydroperoxide glutathione peroxidase 3(gene name synonym)|uniprotkb:GPX3(gene name synonym)|uniprotkb:YIR037W(locus name)|uniprotkb:Glutathione peroxidase homolog 3(gene name synonym) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6332992|imex:IM-14275-1733 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012303.1|sgd:S000001476|ensemblfungi:YIR037W(gene)|ensemblfungi:YIR037W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR029760|interpro:IPR036249|rcsb pdb:3CMI|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661|interpro:IPR029759|mint:P40581|dip:DIP-1275N refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Pi8aaZEVc33CTMPyaM0mpscvLU4559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:07BEC4175D3BD70E|rigid:HrchyQpBgfudR/IRLgRGN3+dgak false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38009 uniprotkb:P40581 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 intact:EBI-7869|ensemblfungi:YIR037W|uniprotkb:D6VVW8 psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:gpx3_yeast(display_long)|uniprotkb:HYR1(gene name)|psi-mi:HYR1(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:Hydrogen peroxide resistance protein 1(gene name synonym)|uniprotkb:Oxidant receptor peroxidase 1(gene name synonym)|uniprotkb:Phospholipid hydroperoxide glutathione peroxidase 3(gene name synonym)|uniprotkb:GPX3(gene name synonym)|uniprotkb:YIR037W(locus name)|uniprotkb:Glutathione peroxidase homolog 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333003|imex:IM-14275-1734 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N refseq:NP_012303.1|sgd:S000001476|ensemblfungi:YIR037W(gene)|ensemblfungi:YIR037W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR029760|interpro:IPR036249|rcsb pdb:3CMI|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661|interpro:IPR029759|mint:P40581|dip:DIP-1275N psi-mi:"MI:0469"(intact) crc64:8ABA71761B512242 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 rogid:Pi8aaZEVc33CTMPyaM0mpscvLU4559292 intact-crc:E33004F238CE3F3B|rigid:urYBwPMk/NGImsSwJUYZcKD+wPk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38234 uniprotkb:P40581 intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C intact:EBI-7869|ensemblfungi:YIR037W|uniprotkb:D6VVW8 psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:gpx3_yeast(display_long)|uniprotkb:HYR1(gene name)|psi-mi:HYR1(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:Hydrogen peroxide resistance protein 1(gene name synonym)|uniprotkb:Oxidant receptor peroxidase 1(gene name synonym)|uniprotkb:Phospholipid hydroperoxide glutathione peroxidase 3(gene name synonym)|uniprotkb:GPX3(gene name synonym)|uniprotkb:YIR037W(locus name)|uniprotkb:Glutathione peroxidase homolog 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333014|imex:IM-14275-1735 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 refseq:NP_012303.1|sgd:S000001476|ensemblfungi:YIR037W(gene)|ensemblfungi:YIR037W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR029760|interpro:IPR036249|rcsb pdb:3CMI|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661|interpro:IPR029759|mint:P40581|dip:DIP-1275N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 rogid:Pi8aaZEVc33CTMPyaM0mpscvLU4559292 intact-crc:724DC6C197E3F43A|rigid:z9zz306tB7yZz7tOg7u8nCRXYGg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54783 uniprotkb:P40581 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 intact:EBI-7869|ensemblfungi:YIR037W|uniprotkb:D6VVW8 psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:gpx3_yeast(display_long)|uniprotkb:HYR1(gene name)|psi-mi:HYR1(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:Hydrogen peroxide resistance protein 1(gene name synonym)|uniprotkb:Oxidant receptor peroxidase 1(gene name synonym)|uniprotkb:Phospholipid hydroperoxide glutathione peroxidase 3(gene name synonym)|uniprotkb:GPX3(gene name synonym)|uniprotkb:YIR037W(locus name)|uniprotkb:Glutathione peroxidase homolog 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333025|imex:IM-14275-1736 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 refseq:NP_012303.1|sgd:S000001476|ensemblfungi:YIR037W(gene)|ensemblfungi:YIR037W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR029760|interpro:IPR036249|rcsb pdb:3CMI|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661|interpro:IPR029759|mint:P40581|dip:DIP-1275N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 rogid:Pi8aaZEVc33CTMPyaM0mpscvLU4559292 intact-crc:9BAFCB7A29A30CFC|rigid:glf/PY2WsPyjKVsJJirRBJqApyk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40581 uniprotkb:Q02785 intact:EBI-7869|ensemblfungi:YIR037W|uniprotkb:D6VVW8 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:gpx3_yeast(display_long)|uniprotkb:HYR1(gene name)|psi-mi:HYR1(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:Hydrogen peroxide resistance protein 1(gene name synonym)|uniprotkb:Oxidant receptor peroxidase 1(gene name synonym)|uniprotkb:Phospholipid hydroperoxide glutathione peroxidase 3(gene name synonym)|uniprotkb:GPX3(gene name synonym)|uniprotkb:YIR037W(locus name)|uniprotkb:Glutathione peroxidase homolog 3(gene name synonym) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333036|imex:IM-14275-1737 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012303.1|sgd:S000001476|ensemblfungi:YIR037W(gene)|ensemblfungi:YIR037W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR029760|interpro:IPR036249|rcsb pdb:3CMI|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661|interpro:IPR029759|mint:P40581|dip:DIP-1275N refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Pi8aaZEVc33CTMPyaM0mpscvLU4559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:5E7ABBC413A2836F|rigid:weoKVkTb2hmvkBeD/eNxBTp2vGs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40581 uniprotkb:Q06451 intact:EBI-7869|ensemblfungi:YIR037W|uniprotkb:D6VVW8 intact:EBI-34275|uniprotkb:D6W4F2|ensemblfungi:YPR156C psi-mi:gpx3_yeast(display_long)|uniprotkb:HYR1(gene name)|psi-mi:HYR1(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:Hydrogen peroxide resistance protein 1(gene name synonym)|uniprotkb:Oxidant receptor peroxidase 1(gene name synonym)|uniprotkb:Phospholipid hydroperoxide glutathione peroxidase 3(gene name synonym)|uniprotkb:GPX3(gene name synonym)|uniprotkb:YIR037W(locus name)|uniprotkb:Glutathione peroxidase homolog 3(gene name synonym) psi-mi:tpo3_yeast(display_long)|uniprotkb:TPO3(gene name)|psi-mi:TPO3(display_short)|uniprotkb:P9584.7(orf name)|uniprotkb:YPR156C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333047|imex:IM-14275-1738 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012303.1|sgd:S000001476|ensemblfungi:YIR037W(gene)|ensemblfungi:YIR037W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR029760|interpro:IPR036249|rcsb pdb:3CMI|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661|interpro:IPR029759|mint:P40581|dip:DIP-1275N refseq:NP_015482.1|sgd:S000006360|mint:Q06451|dip:DIP-3907N|ensemblfungi:YPR156C(gene)|ensemblfungi:YPR156C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - crc64:D260ED161F800502 figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Pi8aaZEVc33CTMPyaM0mpscvLU4559292 rogid:oVpx7Bjk/mK2Q7+/j05tX3gHw7k559292 intact-crc:314E70E7FA888B62|rigid:KfnmuPVqo1f04ObVeuZTyQrTD0g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12462 uniprotkb:P40581 intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C intact:EBI-7869|ensemblfungi:YIR037W|uniprotkb:D6VVW8 psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:gpx3_yeast(display_long)|uniprotkb:HYR1(gene name)|psi-mi:HYR1(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:Hydrogen peroxide resistance protein 1(gene name synonym)|uniprotkb:Oxidant receptor peroxidase 1(gene name synonym)|uniprotkb:Phospholipid hydroperoxide glutathione peroxidase 3(gene name synonym)|uniprotkb:GPX3(gene name synonym)|uniprotkb:YIR037W(locus name)|uniprotkb:Glutathione peroxidase homolog 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333058|imex:IM-14275-1739 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) refseq:NP_012303.1|sgd:S000001476|ensemblfungi:YIR037W(gene)|ensemblfungi:YIR037W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR029760|interpro:IPR036249|rcsb pdb:3CMI|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661|interpro:IPR029759|mint:P40581|dip:DIP-1275N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 rogid:Pi8aaZEVc33CTMPyaM0mpscvLU4559292 intact-crc:2D7808AF4D4FE6CC|rigid:QaFU6vqGEscignZkDeqqvHhIXOw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3E756 uniprotkb:P40581 intact:EBI-2044812|uniprotkb:D6VPX0|ensemblfungi:YBL029C-A intact:EBI-7869|ensemblfungi:YIR037W|uniprotkb:D6VVW8 psi-mi:yb029_yeast(display_long)|uniprotkb:YBL029C-A(locus name) psi-mi:gpx3_yeast(display_long)|uniprotkb:HYR1(gene name)|psi-mi:HYR1(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:Hydrogen peroxide resistance protein 1(gene name synonym)|uniprotkb:Oxidant receptor peroxidase 1(gene name synonym)|uniprotkb:Phospholipid hydroperoxide glutathione peroxidase 3(gene name synonym)|uniprotkb:GPX3(gene name synonym)|uniprotkb:YIR037W(locus name)|uniprotkb:Glutathione peroxidase homolog 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333069|imex:IM-14275-1740 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000007591|refseq:NP_076874.1|mint:Q3E756|ensemblfungi:YBL029C-A(gene)|ensemblfungi:YBL029C-A_mRNA(transcript)|go:"GO:0005886"(plasma membrane) refseq:NP_012303.1|sgd:S000001476|ensemblfungi:YIR037W(gene)|ensemblfungi:YIR037W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR029760|interpro:IPR036249|rcsb pdb:3CMI|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661|interpro:IPR029759|mint:P40581|dip:DIP-1275N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Y9LDkESr65DK5SLFNTw1dBKeqPc559292 rogid:Pi8aaZEVc33CTMPyaM0mpscvLU4559292 intact-crc:3842D1D8E782E2F6|rigid:IgsAQwp/t5SBipnhim4p+oThwjo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40582 uniprotkb:P0C268 intact:EBI-7941|uniprotkb:D6VVW9|ensemblfungi:YIR038C intact:EBI-2044092|uniprotkb:D6VPV9|ensemblfungi:YBL039W-B psi-mi:gst1_yeast(display_long)|uniprotkb:YIR038C(locus name)|uniprotkb:GTT1(gene name)|psi-mi:GTT1(display_short)|uniprotkb:GST-I(gene name synonym) psi-mi:yb39b_yeast(display_long)|uniprotkb:YBL039W-B(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333080|imex:IM-14275-1741 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012304.1|sgd:S000001477|mint:P40582|dip:DIP-2103N|ensemblfungi:YIR038C(gene)|ensemblfungi:YIR038C_mRNA(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010731"(protein glutathionylation)|go:"GO:0071944"(cell periphery)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079 sgd:S000028517|refseq:NP_878045.1|mint:P0C268|ensemblfungi:YBL039W-B(gene)|ensemblfungi:YBL039W-B_mRNA(transcript)|go:"GO:0005777"(peroxisome) psi-mi:"MI:0469"(intact) crc64:3C07D40D29F60DFF - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+bqzHpsoLw4j2qQBzHbkfldR5OU559292 rogid:EfowKSHyZ6Fgw3vWQ74mzPwXTbQ559292 intact-crc:4504BC56532C668E|rigid:jBSJkiUdBgwqZ3fSiOLAaQXjv/Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40582 uniprotkb:P14359 intact:EBI-7941|uniprotkb:D6VVW9|ensemblfungi:YIR038C intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:gst1_yeast(display_long)|uniprotkb:YIR038C(locus name)|uniprotkb:GTT1(gene name)|psi-mi:GTT1(display_short)|uniprotkb:GST-I(gene name synonym) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333091|imex:IM-14275-1742 author score:94.15 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012304.1|sgd:S000001477|mint:P40582|dip:DIP-2103N|ensemblfungi:YIR038C(gene)|ensemblfungi:YIR038C_mRNA(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010731"(protein glutathionylation)|go:"GO:0071944"(cell periphery)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079 refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) crc64:3C07D40D29F60DFF crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:94.15|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+bqzHpsoLw4j2qQBzHbkfldR5OU559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:055FF07A8867B2A2|rigid:CjXgbEr2+ZULd/uPs8WLHIcSJ9M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:P40582 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-7941|uniprotkb:D6VVW9|ensemblfungi:YIR038C psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:gst1_yeast(display_long)|uniprotkb:YIR038C(locus name)|uniprotkb:GTT1(gene name)|psi-mi:GTT1(display_short)|uniprotkb:GST-I(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333102|imex:IM-14275-1743 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N refseq:NP_012304.1|sgd:S000001477|mint:P40582|dip:DIP-2103N|ensemblfungi:YIR038C(gene)|ensemblfungi:YIR038C_mRNA(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010731"(protein glutathionylation)|go:"GO:0071944"(cell periphery)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079 psi-mi:"MI:0469"(intact) - crc64:3C07D40D29F60DFF figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:+bqzHpsoLw4j2qQBzHbkfldR5OU559292 intact-crc:530A386552D5B2F8|rigid:ZKC0qQl2MRRciJZ/OWzEld4tzgQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38756 uniprotkb:P40582 intact:EBI-24431|uniprotkb:D3DKU6|ensemblfungi:YHR003C intact:EBI-7941|uniprotkb:D6VVW9|ensemblfungi:YIR038C psi-mi:tcd1_yeast(display_long)|uniprotkb:TCD1(gene name)|psi-mi:TCD1(display_short)|uniprotkb:"t(6)A37 dehydratase 1"(gene name synonym)|uniprotkb:YHR003C(locus name) psi-mi:gst1_yeast(display_long)|uniprotkb:YIR038C(locus name)|uniprotkb:GTT1(gene name)|psi-mi:GTT1(display_short)|uniprotkb:GST-I(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333113|imex:IM-14275-1744 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011866.1|sgd:S000001045|dip:DIP-4417N|mint:P38756|ensemblfungi:YHR003C(gene)|ensemblfungi:YHR003C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008641"(ubiquitin-like modifier activating enzyme activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0061503"(tRNA threonylcarbamoyladenosine dehydratase)|go:"GO:0061504"(cyclic threonylcarbamoyladenosine biosynthetic process)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR035985 refseq:NP_012304.1|sgd:S000001477|mint:P40582|dip:DIP-2103N|ensemblfungi:YIR038C(gene)|ensemblfungi:YIR038C_mRNA(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010731"(protein glutathionylation)|go:"GO:0071944"(cell periphery)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079 psi-mi:"MI:0469"(intact) - crc64:3C07D40D29F60DFF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Mce7jBtBDJ9bSrw+cQDCbhK8DvY559292 rogid:+bqzHpsoLw4j2qQBzHbkfldR5OU559292 intact-crc:26923EA299257B8D|rigid:JLLRFUGbnFfhKMEmomI1Q232+iA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54783 uniprotkb:P40582 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 intact:EBI-7941|uniprotkb:D6VVW9|ensemblfungi:YIR038C psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:gst1_yeast(display_long)|uniprotkb:YIR038C(locus name)|uniprotkb:GTT1(gene name)|psi-mi:GTT1(display_short)|uniprotkb:GST-I(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333124|imex:IM-14275-1745 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 refseq:NP_012304.1|sgd:S000001477|mint:P40582|dip:DIP-2103N|ensemblfungi:YIR038C(gene)|ensemblfungi:YIR038C_mRNA(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010731"(protein glutathionylation)|go:"GO:0071944"(cell periphery)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079 psi-mi:"MI:0469"(intact) - crc64:3C07D40D29F60DFF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 rogid:+bqzHpsoLw4j2qQBzHbkfldR5OU559292 intact-crc:98AFCB77EE29A43A|rigid:H4jZ5L38JksEK8dcQ5r0o26CitQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:P40582 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-7941|uniprotkb:D6VVW9|ensemblfungi:YIR038C psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:gst1_yeast(display_long)|uniprotkb:YIR038C(locus name)|uniprotkb:GTT1(gene name)|psi-mi:GTT1(display_short)|uniprotkb:GST-I(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333135|imex:IM-14275-1746 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_012304.1|sgd:S000001477|mint:P40582|dip:DIP-2103N|ensemblfungi:YIR038C(gene)|ensemblfungi:YIR038C_mRNA(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010731"(protein glutathionylation)|go:"GO:0071944"(cell periphery)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079 psi-mi:"MI:0469"(intact) - crc64:3C07D40D29F60DFF figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:+bqzHpsoLw4j2qQBzHbkfldR5OU559292 intact-crc:196A859C4A7AB516|rigid:DiHkQtxlOFAPMSi0QY+GTbMHkRU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:P40582 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-7941|uniprotkb:D6VVW9|ensemblfungi:YIR038C psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:gst1_yeast(display_long)|uniprotkb:YIR038C(locus name)|uniprotkb:GTT1(gene name)|psi-mi:GTT1(display_short)|uniprotkb:GST-I(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333146|imex:IM-14275-1747 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_012304.1|sgd:S000001477|mint:P40582|dip:DIP-2103N|ensemblfungi:YIR038C(gene)|ensemblfungi:YIR038C_mRNA(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010731"(protein glutathionylation)|go:"GO:0071944"(cell periphery)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079 psi-mi:"MI:0469"(intact) - crc64:3C07D40D29F60DFF figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:+bqzHpsoLw4j2qQBzHbkfldR5OU559292 intact-crc:03F4EF54E84F42A0|rigid:WcU7bzYbeTIztZMRqZvcz4x9PnQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:P40582 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-7941|uniprotkb:D6VVW9|ensemblfungi:YIR038C psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:gst1_yeast(display_long)|uniprotkb:YIR038C(locus name)|uniprotkb:GTT1(gene name)|psi-mi:GTT1(display_short)|uniprotkb:GST-I(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333157|imex:IM-14275-1748 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 refseq:NP_012304.1|sgd:S000001477|mint:P40582|dip:DIP-2103N|ensemblfungi:YIR038C(gene)|ensemblfungi:YIR038C_mRNA(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010731"(protein glutathionylation)|go:"GO:0071944"(cell periphery)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079 psi-mi:"MI:0469"(intact) - crc64:3C07D40D29F60DFF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:+bqzHpsoLw4j2qQBzHbkfldR5OU559292 intact-crc:63BFE513DDDCDAC4|rigid:PgtsNRnHhLHLkERqnxVjqdZ9qNI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12462 uniprotkb:P40582 intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C intact:EBI-7941|uniprotkb:D6VVW9|ensemblfungi:YIR038C psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:gst1_yeast(display_long)|uniprotkb:YIR038C(locus name)|uniprotkb:GTT1(gene name)|psi-mi:GTT1(display_short)|uniprotkb:GST-I(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333168|imex:IM-14275-1749 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) refseq:NP_012304.1|sgd:S000001477|mint:P40582|dip:DIP-2103N|ensemblfungi:YIR038C(gene)|ensemblfungi:YIR038C_mRNA(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010731"(protein glutathionylation)|go:"GO:0071944"(cell periphery)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079 psi-mi:"MI:0469"(intact) - crc64:3C07D40D29F60DFF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 rogid:+bqzHpsoLw4j2qQBzHbkfldR5OU559292 intact-crc:2E758BC28AC54E0A|rigid:AeZhftfEixibu+YUSrtVvupDjqM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21304 uniprotkb:P40693 intact:EBI-14328|uniprotkb:D6VYJ9|ensemblfungi:YLR196W intact:EBI-15415|uniprotkb:D6W1H5|ensemblfungi:YNL002C psi-mi:pwp1_yeast(display_long)|uniprotkb:L8167.10(orf name)|uniprotkb:YLR196W(locus name)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short) psi-mi:rlp7_yeast(display_long)|uniprotkb:RPL7(gene name synonym)|uniprotkb:N2014(orf name)|uniprotkb:YNL002C(locus name)|uniprotkb:RLP7(gene name)|psi-mi:RLP7(display_short)|uniprotkb:Ribosomal protein L7-like(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333179|imex:IM-14275-1750 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013297.1|sgd:S000004186|ensemblfungi:YLR196W(gene)|ensemblfungi:YLR196W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR044285|mint:P21304|dip:DIP-4203N sgd:S000004947|refseq:NP_014396.3|ensemblfungi:YNL002C(gene)|ensemblfungi:YNL002C_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000465"("exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|rcsb pdb:3JCT|rcsb pdb:4V7F|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6M62|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BTB|dip:DIP-6476N|mint:P40693 psi-mi:"MI:0469"(intact) crc64:FC0189B289494AB5 crc64:64714DDFAFB90B5D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Q1nPXtlkpIw8JosaiYX0PSVNaSw559292 rogid:HR8kGX5foVbBQ/nWTKMM16uB3E8559292 intact-crc:7F6B82CB8A37C452|rigid:MildRPUzcXjvd0ae2Qd1ZuJsOuI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40693 uniprotkb:P53874 intact:EBI-15415|uniprotkb:D6W1H5|ensemblfungi:YNL002C intact:EBI-19873|uniprotkb:D6W101|ensemblfungi:YNL186W psi-mi:rlp7_yeast(display_long)|uniprotkb:RPL7(gene name synonym)|uniprotkb:N2014(orf name)|uniprotkb:YNL002C(locus name)|uniprotkb:RLP7(gene name)|psi-mi:RLP7(display_short)|uniprotkb:Ribosomal protein L7-like(gene name synonym) psi-mi:ubp10_yeast(display_long)|uniprotkb:UBP10(gene name)|psi-mi:UBP10(display_short)|uniprotkb:YNL186W(locus name)|uniprotkb:N1619(orf name)|uniprotkb:Ubiquitin-specific-processing protease 10(gene name synonym)|uniprotkb:Deubiquitinating enzyme 10(gene name synonym)|uniprotkb:Disrupter of telomere silencing protein 4(gene name synonym)|uniprotkb:Ubiquitin thioesterase 10(gene name synonym)|uniprotkb:DOT4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333190|imex:IM-14275-1751 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004947|refseq:NP_014396.3|ensemblfungi:YNL002C(gene)|ensemblfungi:YNL002C_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000465"("exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|rcsb pdb:3JCT|rcsb pdb:4V7F|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6M62|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BTB|dip:DIP-6476N|mint:P40693 refseq:NP_014213.2|sgd:S000005130|ensemblfungi:YNL186W(gene)|ensemblfungi:YNL186W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0043596"(nuclear replication fork)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|rcsb pdb:6RR0|dip:DIP-6664N|mint:P53874 psi-mi:"MI:0469"(intact) crc64:64714DDFAFB90B5D - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HR8kGX5foVbBQ/nWTKMM16uB3E8559292 rogid:Z1rRAI9RLgHeGd7QwLbrf51v5LY559292 intact-crc:4FB36B902A09523B|rigid:LXIn6wDi4igwlwIwXXBOs95I8vg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40958 uniprotkb:Q02785 intact:EBI-10362|ensemblfungi:YJL030W|uniprotkb:D6VWF2 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:mad2_yeast(display_long)|uniprotkb:MAD2(gene name)|psi-mi:MAD2(display_short)|uniprotkb:J1256(orf name)|uniprotkb:YJL030W(locus name) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333201|imex:IM-14275-1752 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003567|ensemblfungi:YJL030W(gene)|ensemblfungi:YJL030W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051312"(chromosome decondensation)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-SCE-141405|reactome:R-SCE-141430|refseq:NP_012504.3|dip:DIP-815N|mint:P40958 refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0pxFckODTcklkGn+JcczltjSHRU559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:C25137E57683942C|rigid:Y41QdW96Kc32BU8TBaDHlkr5jkE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40958 uniprotkb:Q8TGU5 intact:EBI-10362|ensemblfungi:YJL030W|uniprotkb:D6VWF2 intact:EBI-2042814|uniprotkb:D6VQU1|ensemblfungi:YBR296C-A psi-mi:mad2_yeast(display_long)|uniprotkb:MAD2(gene name)|psi-mi:MAD2(display_short)|uniprotkb:J1256(orf name)|uniprotkb:YJL030W(locus name) psi-mi:yb296_yeast(display_long)|uniprotkb:YBR296C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333212|imex:IM-14275-1753 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003567|ensemblfungi:YJL030W(gene)|ensemblfungi:YJL030W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051312"(chromosome decondensation)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-SCE-141405|reactome:R-SCE-141430|refseq:NP_012504.3|dip:DIP-815N|mint:P40958 sgd:S000028605|refseq:NP_878055.3|mint:Q8TGU5|ensemblfungi:YBR296C-A(gene)|ensemblfungi:YBR296C-A_mRNA(transcript)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0pxFckODTcklkGn+JcczltjSHRU559292 rogid:DZubWD7lnwtea4Ne/bK1ITPFaJk559292 intact-crc:4B0BBF2522B322AE|rigid:EZCdN42e2DFzzcvbwjsQqAi9hSQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40961 uniprotkb:Q08979 intact:EBI-13360|ensemblfungi:YGR132C|uniprotkb:D6VUR4 intact:EBI-9638|ensemblfungi:YPL263C|uniprotkb:D6W3A7 psi-mi:phb1_yeast(display_long)|uniprotkb:PHB1(gene name)|psi-mi:PHB1(display_short)|uniprotkb:PHB(gene name synonym)|uniprotkb:YGR132C(locus name) psi-mi:kel3_yeast(display_long)|uniprotkb:KEL3(gene name)|psi-mi:KEL3(display_short)|uniprotkb:YPL263C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333223|imex:IM-14275-1754 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003364|refseq:NP_011648.3|ensemblfungi:YGR132C(gene)|ensemblfungi:YGR132C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0070584"(mitochondrion morphogenesis)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:P40961|dip:DIP-6653N ensemblfungi:YPL263C(gene)|go:"GO:0005737"(cytoplasm)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR025183|ensemblfungi:YPL263C_mRNA(transcript)|refseq:NP_015060.1|sgd:S000006184|dip:DIP-3926N|mint:Q08979 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rgCg+CnNS7Z29vKWhhTsTwXecVM559292 rogid:uMF7Wf2cxn5RlDULmgxzx2h59DE559292 intact-crc:7E54B1198FFE2EB4|rigid:5yilfK1zkP7HpRW8ErK9vEFchGU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CX10 uniprotkb:P40993 intact:EBI-6315262|ensemblfungi:YOR393W|ensemblfungi:YPL281C|uniprotkb:D6W385|uniprotkb:Q12007|uniprotkb:Q7LGJ4 intact:EBI-15622|uniprotkb:D6VTA1|uniprotkb:Q6B1P4|ensemblfungi:YDR478W psi-mi:err1_yeast(display_long)|uniprotkb:ERR1(gene name)|psi-mi:ERR1(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:2-phosphoglycerate dehydratase(gene name synonym)|uniprotkb:YOR393W(locus name) psi-mi:rmrp_yeast(display_long)|uniprotkb:SNM1(gene name)|psi-mi:SNM1(display_short)|uniprotkb:YDR478W(locus name)|uniprotkb:D8035.21(orf name)|uniprotkb:RNase MRP 22.5 kDa subunit(gene name synonym)|uniprotkb:RNA-processing protein SNM1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333234|imex:IM-14275-1755 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR393W(gene)|ensemblfungi:YOR393W_mRNA(transcript)|ensemblfungi:YPL281C(gene)|ensemblfungi:YPL281C_mRNA(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0006096"(glycolytic process)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|reactome:R-SCE-70171|reactome:R-SCE-70263|mint:P0CX10|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|refseq:NP_015038.1|refseq:NP_015042.1|sgd:S000005920|interpro:IPR029017|interpro:IPR036849 sgd:S000002886|refseq:NP_010766.3|ensemblfungi:YDR478W(gene)|ensemblfungi:YDR478W_mRNA(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0004518"(nuclease activity)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0030541"(plasmid partitioning)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR007175(RNAse P, Rpr2/Rpp21 subunit)|rcsb pdb:6W6V|rcsb pdb:7C79|rcsb pdb:7C7A|dip:DIP-5233N|mint:P40993 psi-mi:"MI:0469"(intact) - crc64:67C262585D3BEA3A figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Vusa5LQZe98ke/mcTRdEnXReZDc559292 rogid:AJb3/fr3PHRtve3YsSnjMkJ6ZgY559292 intact-crc:497702D2D8891577|rigid:9mo7xM+eKA8WEk1nKFErGHBoMFY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40993 uniprotkb:Q07843 intact:EBI-15622|uniprotkb:D6VTA1|uniprotkb:Q6B1P4|ensemblfungi:YDR478W intact:EBI-32747|uniprotkb:D6VXX2|ensemblfungi:YLL033W psi-mi:rmrp_yeast(display_long)|uniprotkb:SNM1(gene name)|psi-mi:SNM1(display_short)|uniprotkb:YDR478W(locus name)|uniprotkb:D8035.21(orf name)|uniprotkb:RNase MRP 22.5 kDa subunit(gene name synonym)|uniprotkb:RNA-processing protein SNM1(gene name synonym) psi-mi:irc19_yeast(display_long)|uniprotkb:IRC19(gene name)|psi-mi:IRC19(display_short)|uniprotkb:RRG4(gene name synonym)|uniprotkb:YLL033W(locus name)|uniprotkb:Respiratory growth protein 4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333245|imex:IM-14275-1756 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002886|refseq:NP_010766.3|ensemblfungi:YDR478W(gene)|ensemblfungi:YDR478W_mRNA(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0004518"(nuclease activity)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0030541"(plasmid partitioning)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR007175(RNAse P, Rpr2/Rpp21 subunit)|rcsb pdb:6W6V|rcsb pdb:7C79|rcsb pdb:7C7A|dip:DIP-5233N|mint:P40993 sgd:S000003956|refseq:NP_013067.1|dip:DIP-2875N|mint:Q07843|ensemblfungi:YLL033W(gene)|ensemblfungi:YLL033W_mRNA(transcript)|go:"GO:0006312"(mitotic recombination)|go:"GO:0030437"(ascospore formation)|interpro:IPR016613(Uncharacterised conserved protein UCP013329) psi-mi:"MI:0469"(intact) crc64:67C262585D3BEA3A crc64:4B1D040696A4CF22 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AJb3/fr3PHRtve3YsSnjMkJ6ZgY559292 rogid:Ij3cZx+Kk0MKLUfR7uVh8cp0pvU559292 intact-crc:06BBD5CA2DBE0AF5|rigid:hNMzRvcTFSw8ksBqmW2abrwnTGc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10127 uniprotkb:P40994 intact:EBI-2233|uniprotkb:D6VV79|ensemblfungi:YGL256W intact:EBI-2824|uniprotkb:D6W2F5|ensemblfungi:YOR094W psi-mi:adh4_yeast(display_long)|uniprotkb:ADH4(gene name)|psi-mi:ADH4(display_short)|uniprotkb:YGL256W(locus name)|uniprotkb:NRC465(orf name)|uniprotkb:ZRG5(gene name synonym)|uniprotkb:Alcohol dehydrogenase IV(gene name synonym) psi-mi:arf3_yeast(display_long)|uniprotkb:ARF3(gene name)|psi-mi:ARF3(display_short)|uniprotkb:YOR3172W(orf name)|uniprotkb:YOR094W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333256|imex:IM-14275-1757 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011258.2|sgd:S000003225|dip:DIP-4812N|mint:P10127|ensemblfungi:YGL256W(gene)|ensemblfungi:YGL256W_mRNA(transcript)|go:"GO:0000947"(amino acid catabolic process to alcohol via Ehrlich pathway)|go:"GO:0004022"("alcohol dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006113"(fermentation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001670(Iron-containing alcohol dehydrogenase)|interpro:IPR018211|interpro:IPR039697 refseq:NP_014737.1|sgd:S000005620|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P40994|interpro:IPR041838|ensemblfungi:YOR094W(gene)|ensemblfungi:YOR094W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010513"(positive regulation of phosphatidylinositol biosynthetic process)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0036267"(invasive filamentous growth)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization) psi-mi:"MI:0469"(intact) crc64:7DFFD43830FB269B - figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fbgaUT1lKT6O6lYODaI0xuqspzM559292 rogid:uC+fupPUZajD7m7pLEO/K0Kuudo559292 intact-crc:9A5A39F37EE0AC26|rigid:eREtNKnA/gF+7HIELKl+qmRg9YU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12462 uniprotkb:P40994 intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C intact:EBI-2824|uniprotkb:D6W2F5|ensemblfungi:YOR094W psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:arf3_yeast(display_long)|uniprotkb:ARF3(gene name)|psi-mi:ARF3(display_short)|uniprotkb:YOR3172W(orf name)|uniprotkb:YOR094W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333267|imex:IM-14275-1758 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) refseq:NP_014737.1|sgd:S000005620|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P40994|interpro:IPR041838|ensemblfungi:YOR094W(gene)|ensemblfungi:YOR094W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010513"(positive regulation of phosphatidylinositol biosynthetic process)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0036267"(invasive filamentous growth)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 rogid:uC+fupPUZajD7m7pLEO/K0Kuudo559292 intact-crc:ABD207D9015A7834|rigid:3NP238NFpajqqBShZQdYf/5Hm0s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41697 uniprotkb:P41697 intact:EBI-3857|uniprotkb:D6VYW2|ensemblfungi:YLR319C intact:EBI-3857|uniprotkb:D6VYW2|ensemblfungi:YLR319C psi-mi:bud6_yeast(display_long)|uniprotkb:BUD6(gene name)|psi-mi:BUD6(display_short)|uniprotkb:Actin-interacting protein 3(gene name synonym)|uniprotkb:AIP3(gene name synonym)|uniprotkb:L8543.5(orf name)|uniprotkb:YLR319C(locus name) psi-mi:bud6_yeast(display_long)|uniprotkb:BUD6(gene name)|psi-mi:BUD6(display_short)|uniprotkb:Actin-interacting protein 3(gene name synonym)|uniprotkb:AIP3(gene name synonym)|uniprotkb:L8543.5(orf name)|uniprotkb:YLR319C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333278|imex:IM-14275-1759 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013423.1|sgd:S000004311|dip:DIP-880N|mint:P41697|ensemblfungi:YLR319C(gene)|ensemblfungi:YLR319C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000133"(polarisome)|go:"GO:0003779"(actin binding)|go:"GO:0005519"(cytoskeletal regulatory protein binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034652"(extrachromosomal circular DNA localization involved in cell aging)|go:"GO:0043332"(mating projection tip)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051286"(cell tip)|go:"GO:0090338"(positive regulation of formin-nucleated actin cable assembly)|go:"GO:0099503"(secretory vesicle)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR005613(Actin interacting protein 3)|interpro:IPR022782|rcsb pdb:3OKQ|rcsb pdb:3ONX|rcsb pdb:4WYB refseq:NP_013423.1|sgd:S000004311|dip:DIP-880N|mint:P41697|ensemblfungi:YLR319C(gene)|ensemblfungi:YLR319C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000133"(polarisome)|go:"GO:0003779"(actin binding)|go:"GO:0005519"(cytoskeletal regulatory protein binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034652"(extrachromosomal circular DNA localization involved in cell aging)|go:"GO:0043332"(mating projection tip)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051286"(cell tip)|go:"GO:0090338"(positive regulation of formin-nucleated actin cable assembly)|go:"GO:0099503"(secretory vesicle)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR005613(Actin interacting protein 3)|interpro:IPR022782|rcsb pdb:3OKQ|rcsb pdb:3ONX|rcsb pdb:4WYB psi-mi:"MI:0469"(intact) crc64:4BAE8F541B8BDF1F crc64:4BAE8F541B8BDF1F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:eyN8DMoUVDSGMzkV901bJJgSt4M559292 rogid:eyN8DMoUVDSGMzkV901bJJgSt4M559292 intact-crc:FC46E65A1A4AFAB2|rigid:MTRdhqXA8r+9fXB0Bad/ZtebWsc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P41806 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-20323|uniprotkb:D6VUN7|uniprotkb:Q6Q5Q3|ensemblfungi:YGR105W psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:vma21_yeast(display_long)|uniprotkb:VMA21(gene name)|psi-mi:VMA21(display_short)|uniprotkb:YGR105W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333289|imex:IM-14275-1760 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 sgd:S000003337|refseq:NP_011619.3|ensemblfungi:YGR105W(gene)|ensemblfungi:YGR105W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|interpro:IPR019013|dip:DIP-5526N|mint:P41806 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:Ailhh4PtjuOy5Jiwx8aN7cHFddk559292 intact-crc:644F62A6525D55F0|rigid:nzOjkA0AkXtcgH8OvRkZIUxY39g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32366 uniprotkb:P41806 intact:EBI-20201|uniprotkb:D6VZ81|ensemblfungi:YLR447C intact:EBI-20323|uniprotkb:D6VUN7|uniprotkb:Q6Q5Q3|ensemblfungi:YGR105W psi-mi:va0d_yeast(display_long)|uniprotkb:VMA6(gene name)|psi-mi:VMA6(display_short)|uniprotkb:YLR447C(locus name)|uniprotkb:L9324.8(orf name)|uniprotkb:Vacuolar proton pump subunit d(gene name synonym)|uniprotkb:V-ATPase 39 kDa subunit(gene name synonym)|uniprotkb:V-ATPase subunit M39(gene name synonym) psi-mi:vma21_yeast(display_long)|uniprotkb:VMA21(gene name)|psi-mi:VMA21(display_short)|uniprotkb:YGR105W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333300|imex:IM-14275-1761 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004439|refseq:NP_013552.3|mint:P32366|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR036079|interpro:IPR044911|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|ensemblfungi:YLR447C(gene)|ensemblfungi:YLR447C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|rcsb pdb:6PE4|dip:DIP-1737N sgd:S000003337|refseq:NP_011619.3|ensemblfungi:YGR105W(gene)|ensemblfungi:YGR105W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|interpro:IPR019013|dip:DIP-5526N|mint:P41806 psi-mi:"MI:0469"(intact) crc64:53A19450CAF35632 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ux3Cd8Fl9t/GGgcKAzJevZQFWnE559292 rogid:Ailhh4PtjuOy5Jiwx8aN7cHFddk559292 intact-crc:9BBE7663F58A4851|rigid:ufY/40OL2UrkPKjrEFQK+0bRfG8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41806 uniprotkb:P32563 intact:EBI-20323|uniprotkb:D6VUN7|uniprotkb:Q6Q5Q3|ensemblfungi:YGR105W intact:EBI-20455|uniprotkb:D6W2X0|ensemblfungi:YOR270C psi-mi:vma21_yeast(display_long)|uniprotkb:VMA21(gene name)|psi-mi:VMA21(display_short)|uniprotkb:YGR105W(locus name) psi-mi:vph1_yeast(display_long)|uniprotkb:VPH1(gene name)|psi-mi:VPH1(display_short)|uniprotkb:Vacuolar proton pump a subunit(gene name synonym)|uniprotkb:V-ATPase 95 kDa subunit(gene name synonym)|uniprotkb:Vacuolar pH protein 1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase subunit a 1(gene name synonym)|uniprotkb:YOR270C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333311|imex:IM-14275-1762 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003337|refseq:NP_011619.3|ensemblfungi:YGR105W(gene)|ensemblfungi:YGR105W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|interpro:IPR019013|dip:DIP-5526N|mint:P41806 sgd:S000005796|refseq:NP_014913.3|ensemblfungi:YOR270C(gene)|ensemblfungi:YOR270C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0034622"|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:0071469"(cellular response to alkaline pH)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|rcsb pdb:2JTW|rcsb pdb:2NVJ|rcsb pdb:2RPW|rcsb pdb:3J9T|go:"GO:0007035"(vacuolar acidification)|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5I1M|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6HH0|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2960N|mint:P32563 psi-mi:"MI:0469"(intact) - crc64:77709A914410CD4D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ailhh4PtjuOy5Jiwx8aN7cHFddk559292 rogid:c+aKW/ZUnBlGW7ZqOLD/0mpICdQ559292 intact-crc:E8DD3075BD0E3E0E|rigid:P4Fp6jIUigCXIAPXtx1dR+XBHJU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41806 uniprotkb:P32610 intact:EBI-20323|uniprotkb:D6VUN7|uniprotkb:Q6Q5Q3|ensemblfungi:YGR105W intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W psi-mi:vma21_yeast(display_long)|uniprotkb:VMA21(gene name)|psi-mi:VMA21(display_short)|uniprotkb:YGR105W(locus name) psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333322|imex:IM-14275-1763 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003337|refseq:NP_011619.3|ensemblfungi:YGR105W(gene)|ensemblfungi:YGR105W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|interpro:IPR019013|dip:DIP-5526N|mint:P41806 refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610 psi-mi:"MI:0469"(intact) - crc64:FDE93E1FAF0AEC5B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ailhh4PtjuOy5Jiwx8aN7cHFddk559292 rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292 intact-crc:B4CB937865BB3D8B|rigid:FdH6mnDnS95DnWSiFp78urM52i8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41806 uniprotkb:P39111 intact:EBI-20323|uniprotkb:D6VUN7|uniprotkb:Q6Q5Q3|ensemblfungi:YGR105W intact:EBI-20272|uniprotkb:D6VUF5|ensemblfungi:YGR020C psi-mi:vma21_yeast(display_long)|uniprotkb:VMA21(gene name)|psi-mi:VMA21(display_short)|uniprotkb:YGR105W(locus name) psi-mi:vatf_yeast(display_long)|uniprotkb:VMA7(gene name)|psi-mi:VMA7(display_short)|uniprotkb:YGR020C(locus name)|uniprotkb:Vacuolar proton pump subunit F(gene name synonym)|uniprotkb:V-ATPase 14 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333333|imex:IM-14275-1764 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003337|refseq:NP_011619.3|ensemblfungi:YGR105W(gene)|ensemblfungi:YGR105W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|interpro:IPR019013|dip:DIP-5526N|mint:P41806 refseq:NP_011534.1|sgd:S000003252|ensemblfungi:YGR020C(gene)|ensemblfungi:YGR020C_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016020"(membrane)|go:"GO:0042625"(ATPase-coupled ion transmembrane transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005772(ATPase, V1 complex, subunit F, eukaryotic)|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|interpro:IPR036906|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4IX9|rcsb pdb:4RND|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2077N|mint:P39111 psi-mi:"MI:0469"(intact) - crc64:D21EC0980EB99DFF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ailhh4PtjuOy5Jiwx8aN7cHFddk559292 rogid:VtthQl2jj9fpjv3psX0YUNbIAKU559292 intact-crc:64B3FED7D8DDBF89|rigid:xc128QvgsrA5h0cLhdmUT99ZWbw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41807 uniprotkb:P41806 intact:EBI-20281|uniprotkb:D6W446|ensemblfungi:YPR036W intact:EBI-20323|uniprotkb:D6VUN7|uniprotkb:Q6Q5Q3|ensemblfungi:YGR105W psi-mi:vath_yeast(display_long)|uniprotkb:YP3085.02(orf name)|uniprotkb:VMA13(gene name)|psi-mi:VMA13(display_short)|uniprotkb:CLS11(gene name synonym)|uniprotkb:YPR036W(locus name)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 54 kDa subunit(gene name synonym) psi-mi:vma21_yeast(display_long)|uniprotkb:VMA21(gene name)|psi-mi:VMA21(display_short)|uniprotkb:YGR105W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333344|imex:IM-14275-1765 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015361.1|sgd:S000006240|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|rcsb pdb:1HO8|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YPR036W(gene)|ensemblfungi:YPR036W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|dip:DIP-6640N|mint:P41807 sgd:S000003337|refseq:NP_011619.3|ensemblfungi:YGR105W(gene)|ensemblfungi:YGR105W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|interpro:IPR019013|dip:DIP-5526N|mint:P41806 psi-mi:"MI:0469"(intact) crc64:54131FF9C2C87594 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kEXWvOsnTk0WdgGOny+mufz4lTo559292 rogid:Ailhh4PtjuOy5Jiwx8aN7cHFddk559292 intact-crc:FAF8E552F2B41644|rigid:wD8CDbksBxNxtl6ydL2mApxj6n0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41806 uniprotkb:P53262 intact:EBI-20323|uniprotkb:D6VUN7|uniprotkb:Q6Q5Q3|ensemblfungi:YGR105W intact:EBI-2061527|uniprotkb:D6VUN8|ensemblfungi:YGR106C psi-mi:vma21_yeast(display_long)|uniprotkb:VMA21(gene name)|psi-mi:VMA21(display_short)|uniprotkb:YGR105W(locus name) psi-mi:voa1_yeast(display_long)|uniprotkb:YGR106C(locus name)|uniprotkb:VOA1(gene name)|psi-mi:VOA1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333355|imex:IM-14275-1766 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003337|refseq:NP_011619.3|ensemblfungi:YGR105W(gene)|ensemblfungi:YGR105W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|interpro:IPR019013|dip:DIP-5526N|mint:P41806 sgd:S000003338|refseq:NP_011620.1|mint:P53262|ensemblfungi:YGR106C(gene)|ensemblfungi:YGR106C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034622"|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|rcsb pdb:6PE4|rcsb pdb:6PE5 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ailhh4PtjuOy5Jiwx8aN7cHFddk559292 rogid:lKLIonttSEX36IQaIKlzxS/Cdxg559292 intact-crc:86DD0B82F69F2BA1|rigid:zNTbNrHMhU38rfkDMuVOFVhX5Hs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41806 uniprotkb:P54837 intact:EBI-20323|uniprotkb:D6VUN7|uniprotkb:Q6Q5Q3|ensemblfungi:YGR105W intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:vma21_yeast(display_long)|uniprotkb:VMA21(gene name)|psi-mi:VMA21(display_short)|uniprotkb:YGR105W(locus name) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333366|imex:IM-14275-1767 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003337|refseq:NP_011619.3|ensemblfungi:YGR105W(gene)|ensemblfungi:YGR105W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|interpro:IPR019013|dip:DIP-5526N|mint:P41806 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ailhh4PtjuOy5Jiwx8aN7cHFddk559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:69B5853F9A44BF32|rigid:rZF+NoKZFfWC5KNPhbq8yLC2ql8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32563 uniprotkb:P41807 intact:EBI-20455|uniprotkb:D6W2X0|ensemblfungi:YOR270C intact:EBI-20281|uniprotkb:D6W446|ensemblfungi:YPR036W psi-mi:vph1_yeast(display_long)|uniprotkb:VPH1(gene name)|psi-mi:VPH1(display_short)|uniprotkb:Vacuolar proton pump a subunit(gene name synonym)|uniprotkb:V-ATPase 95 kDa subunit(gene name synonym)|uniprotkb:Vacuolar pH protein 1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase subunit a 1(gene name synonym)|uniprotkb:YOR270C(locus name) psi-mi:vath_yeast(display_long)|uniprotkb:YP3085.02(orf name)|uniprotkb:VMA13(gene name)|psi-mi:VMA13(display_short)|uniprotkb:CLS11(gene name synonym)|uniprotkb:YPR036W(locus name)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 54 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333377|imex:IM-14275-1768 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005796|refseq:NP_014913.3|ensemblfungi:YOR270C(gene)|ensemblfungi:YOR270C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0034622"|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:0071469"(cellular response to alkaline pH)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|rcsb pdb:2JTW|rcsb pdb:2NVJ|rcsb pdb:2RPW|rcsb pdb:3J9T|go:"GO:0007035"(vacuolar acidification)|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5I1M|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6HH0|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2960N|mint:P32563 refseq:NP_015361.1|sgd:S000006240|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|rcsb pdb:1HO8|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YPR036W(gene)|ensemblfungi:YPR036W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|dip:DIP-6640N|mint:P41807 psi-mi:"MI:0469"(intact) crc64:77709A914410CD4D crc64:54131FF9C2C87594 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:c+aKW/ZUnBlGW7ZqOLD/0mpICdQ559292 rogid:kEXWvOsnTk0WdgGOny+mufz4lTo559292 intact-crc:77643B5398FA605A|rigid:Itsmnft8sFW/soD6l5nvji5GU/A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41807 uniprotkb:P38310 intact:EBI-20281|uniprotkb:D6W446|ensemblfungi:YPR036W intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:vath_yeast(display_long)|uniprotkb:YP3085.02(orf name)|uniprotkb:VMA13(gene name)|psi-mi:VMA13(display_short)|uniprotkb:CLS11(gene name synonym)|uniprotkb:YPR036W(locus name)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 54 kDa subunit(gene name synonym) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333388|imex:IM-14275-1769 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015361.1|sgd:S000006240|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|rcsb pdb:1HO8|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YPR036W(gene)|ensemblfungi:YPR036W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|dip:DIP-6640N|mint:P41807 refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) crc64:54131FF9C2C87594 crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kEXWvOsnTk0WdgGOny+mufz4lTo559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:9A2ADA44405907D1|rigid:Hp5o1ThKTuKfPv4yYxM8vZFL1Uo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39111 uniprotkb:P41807 intact:EBI-20272|uniprotkb:D6VUF5|ensemblfungi:YGR020C intact:EBI-20281|uniprotkb:D6W446|ensemblfungi:YPR036W psi-mi:vatf_yeast(display_long)|uniprotkb:VMA7(gene name)|psi-mi:VMA7(display_short)|uniprotkb:YGR020C(locus name)|uniprotkb:Vacuolar proton pump subunit F(gene name synonym)|uniprotkb:V-ATPase 14 kDa subunit(gene name synonym) psi-mi:vath_yeast(display_long)|uniprotkb:YP3085.02(orf name)|uniprotkb:VMA13(gene name)|psi-mi:VMA13(display_short)|uniprotkb:CLS11(gene name synonym)|uniprotkb:YPR036W(locus name)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 54 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333399|imex:IM-14275-1770 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011534.1|sgd:S000003252|ensemblfungi:YGR020C(gene)|ensemblfungi:YGR020C_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016020"(membrane)|go:"GO:0042625"(ATPase-coupled ion transmembrane transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005772(ATPase, V1 complex, subunit F, eukaryotic)|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|interpro:IPR036906|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4IX9|rcsb pdb:4RND|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2077N|mint:P39111 refseq:NP_015361.1|sgd:S000006240|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|rcsb pdb:1HO8|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YPR036W(gene)|ensemblfungi:YPR036W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|dip:DIP-6640N|mint:P41807 psi-mi:"MI:0469"(intact) crc64:D21EC0980EB99DFF crc64:54131FF9C2C87594 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VtthQl2jj9fpjv3psX0YUNbIAKU559292 rogid:kEXWvOsnTk0WdgGOny+mufz4lTo559292 intact-crc:FB0AF5F1FD29E1DD|rigid:db4/7FDFjAyUfYQ2OVU5n5gtw1s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41807 uniprotkb:P41807 intact:EBI-20281|uniprotkb:D6W446|ensemblfungi:YPR036W intact:EBI-20281|uniprotkb:D6W446|ensemblfungi:YPR036W psi-mi:vath_yeast(display_long)|uniprotkb:YP3085.02(orf name)|uniprotkb:VMA13(gene name)|psi-mi:VMA13(display_short)|uniprotkb:CLS11(gene name synonym)|uniprotkb:YPR036W(locus name)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 54 kDa subunit(gene name synonym) psi-mi:vath_yeast(display_long)|uniprotkb:YP3085.02(orf name)|uniprotkb:VMA13(gene name)|psi-mi:VMA13(display_short)|uniprotkb:CLS11(gene name synonym)|uniprotkb:YPR036W(locus name)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 54 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333410|imex:IM-14275-1771 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015361.1|sgd:S000006240|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|rcsb pdb:1HO8|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YPR036W(gene)|ensemblfungi:YPR036W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|dip:DIP-6640N|mint:P41807 refseq:NP_015361.1|sgd:S000006240|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|rcsb pdb:1HO8|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YPR036W(gene)|ensemblfungi:YPR036W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|dip:DIP-6640N|mint:P41807 psi-mi:"MI:0469"(intact) crc64:54131FF9C2C87594 crc64:54131FF9C2C87594 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kEXWvOsnTk0WdgGOny+mufz4lTo559292 rogid:kEXWvOsnTk0WdgGOny+mufz4lTo559292 intact-crc:FBF8E5564FCD8E06|rigid:aHmDDUS8nGwzARciWhMJ1nAGVnM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53262 uniprotkb:P41807 intact:EBI-2061527|uniprotkb:D6VUN8|ensemblfungi:YGR106C intact:EBI-20281|uniprotkb:D6W446|ensemblfungi:YPR036W psi-mi:voa1_yeast(display_long)|uniprotkb:YGR106C(locus name)|uniprotkb:VOA1(gene name)|psi-mi:VOA1(display_short) psi-mi:vath_yeast(display_long)|uniprotkb:YP3085.02(orf name)|uniprotkb:VMA13(gene name)|psi-mi:VMA13(display_short)|uniprotkb:CLS11(gene name synonym)|uniprotkb:YPR036W(locus name)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 54 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333421|imex:IM-14275-1772 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003338|refseq:NP_011620.1|mint:P53262|ensemblfungi:YGR106C(gene)|ensemblfungi:YGR106C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034622"|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|rcsb pdb:6PE4|rcsb pdb:6PE5 refseq:NP_015361.1|sgd:S000006240|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|rcsb pdb:1HO8|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YPR036W(gene)|ensemblfungi:YPR036W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|dip:DIP-6640N|mint:P41807 psi-mi:"MI:0469"(intact) - crc64:54131FF9C2C87594 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lKLIonttSEX36IQaIKlzxS/Cdxg559292 rogid:kEXWvOsnTk0WdgGOny+mufz4lTo559292 intact-crc:87DD0B864BE6B3E3|rigid:uY/rmdafZyfrZnbjqqsg7mRKsfQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41809 uniprotkb:Q04048 intact:EBI-8364|uniprotkb:Q04051|uniprotkb:D6VT50|ensemblfungi:YDR420W intact:EBI-540|uniprotkb:D6VT47|ensemblfungi:YDR416W psi-mi:hkr1_yeast(display_long)|uniprotkb:YDR420W(locus name)|uniprotkb:HKR1(gene name)|psi-mi:HKR1(display_short)|uniprotkb:Hansenula MRAKII killer toxin-resistant protein 1(gene name synonym) psi-mi:syf1_yeast(display_long)|uniprotkb:SYF1(gene name)|psi-mi:SYF1(display_short)|uniprotkb:NTC90(gene name synonym)|uniprotkb:Synthetic lethal with CDC40 protein 1(gene name synonym)|uniprotkb:PRP19-associated complex protein 90(gene name synonym)|uniprotkb:YDR416W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333432|imex:IM-14275-1773 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010708.1|sgd:S000002828|mint:P41809|interpro:IPR039295|ensemblfungi:YDR420W(gene)|ensemblfungi:YDR420W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006075"("(1->3)-beta-D-glucan biosynthetic process")|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0009986"(cell surface)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization) refseq:NP_010704.1|sgd:S000002824|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|rcsb pdb:5Y88|ensemblfungi:YDR416W(gene)|ensemblfungi:YDR416W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|dip:DIP-1681N|mint:Q04048 psi-mi:"MI:0469"(intact) - crc64:ED4368A624A40E7C figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3L+LNEsSp2LXueSY+HVvf2lBKZE559292 rogid:+1TwiqsQv1IcWxuoIWcJGtTCUFU559292 intact-crc:8C81E6844FF1A169|rigid:4SN53Q2Cg2PTF1UsvyycnpioSS4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40210 uniprotkb:P41896 intact:EBI-27280|uniprotkb:D6VZW3|ensemblfungi:YMR140W intact:EBI-18916|uniprotkb:D6VUE2|ensemblfungi:YGR005C psi-mi:sip5_yeast(display_long)|uniprotkb:YMR140W(locus name)|uniprotkb:YM9375.09(orf name)|uniprotkb:SIP5(gene name)|psi-mi:SIP5(display_short)|uniprotkb:SNF1-interacting protein 5(gene name synonym) psi-mi:t2fb_yeast(display_long)|uniprotkb:YGR005C(locus name)|uniprotkb:TFG2(gene name)|psi-mi:TFG2(display_short)|uniprotkb:TFIIF-beta(gene name synonym)|uniprotkb:TFIIF medium subunit(gene name synonym)|uniprotkb:Transcription factor G 54 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333443|imex:IM-14275-1774 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004748|refseq:NP_013860.1|mint:P40210|dip:DIP-4656N|ensemblfungi:YMR140W(gene)|ensemblfungi:YMR140W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0042149"(cellular response to glucose starvation)|interpro:IPR039301 ensemblfungi:YGR005C(gene)|ensemblfungi:YGR005C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001111"(promoter clearance from RNA polymerase II promoter)|go:"GO:0001174"(transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0003677"(DNA binding)|go:"GO:0005674"(transcription factor TFIIF complex)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|interpro:IPR003196(Transcription initiation factor IIF, beta subunit)|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|interpro:IPR011039(Transcription Factor IIF, Rap30/Rap74, interaction)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040450|interpro:IPR040504|rcsb pdb:4V1N|rcsb pdb:4V1O|sgd:S000003237|refseq:NP_011519.3|dip:DIP-1152N|mint:P41896 psi-mi:"MI:0469"(intact) - crc64:DDDA895446BBF26F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6WSFQ9V598lJW1o+h2DCP7vRyeA559292 rogid:v+bk6NVZDN+wXpCa+37sl26PrR4559292 intact-crc:C118406455A397A4|rigid:3pvs5pmGW2oG6OW3V7mjTwo4eVg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41896 uniprotkb:P52490 intact:EBI-18916|uniprotkb:D6VUE2|ensemblfungi:YGR005C intact:EBI-19777|uniprotkb:D6VS79|ensemblfungi:YDR092W psi-mi:t2fb_yeast(display_long)|uniprotkb:YGR005C(locus name)|uniprotkb:TFG2(gene name)|psi-mi:TFG2(display_short)|uniprotkb:TFIIF-beta(gene name synonym)|uniprotkb:TFIIF medium subunit(gene name synonym)|uniprotkb:Transcription factor G 54 kDa subunit(gene name synonym) psi-mi:ubc13_yeast(display_long)|uniprotkb:UBC13(gene name)|psi-mi:UBC13(display_short)|uniprotkb:YDR092W(locus name)|uniprotkb:YD6652.04(orf name)|uniprotkb:Ubiquitin-protein ligase 13(gene name synonym)|uniprotkb:Ubiquitin carrier protein 13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 13(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333454|imex:IM-14275-1775 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR005C(gene)|ensemblfungi:YGR005C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001111"(promoter clearance from RNA polymerase II promoter)|go:"GO:0001174"(transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0003677"(DNA binding)|go:"GO:0005674"(transcription factor TFIIF complex)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|interpro:IPR003196(Transcription initiation factor IIF, beta subunit)|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|interpro:IPR011039(Transcription Factor IIF, Rap30/Rap74, interaction)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040450|interpro:IPR040504|rcsb pdb:4V1N|rcsb pdb:4V1O|sgd:S000003237|refseq:NP_011519.3|dip:DIP-1152N|mint:P41896 sgd:S000002499|ensemblfungi:YDR092W(gene)|ensemblfungi:YDR092W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006301"(postreplication repair)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0044395"(protein targeting to vacuolar membrane)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1JAT|rcsb pdb:1JBB|rcsb pdb:2GMI|rcsb pdb:4FH1|rcsb pdb:5OJW|reactome:R-SCE-8866654|reactome:R-SCE-9020702|reactome:R-SCE-9646399|reactome:R-SCE-983168|refseq:NP_010377.3|dip:DIP-5486N|mint:P52490 psi-mi:"MI:0469"(intact) crc64:DDDA895446BBF26F crc64:445558F8F193275B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:v+bk6NVZDN+wXpCa+37sl26PrR4559292 rogid:5nTtjUZ2IpzHhrj1UU6NlaRW53k559292 intact-crc:5DFD6A6FDC28B727|rigid:YkFy1Z8abeCXhsb+iqhX8Il/Rzo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35208 uniprotkb:P41912 intact:EBI-17700|uniprotkb:D6VW59|ensemblfungi:YJL127C intact:EBI-2087870|uniprotkb:D6W1V7|ensemblfungi:YOL110W psi-mi:spt10_yeast(display_long)|uniprotkb:SPT10(gene name)|psi-mi:SPT10(display_short)|uniprotkb:CRE1(gene name synonym)|uniprotkb:SUD1(gene name synonym)|uniprotkb:YJL127C(locus name)|uniprotkb:J0702(orf name) psi-mi:erfd_yeast(display_long)|uniprotkb:YOL110W(locus name)|uniprotkb:HRC237(orf name)|uniprotkb:SHR5(gene name)|psi-mi:SHR5(display_short)|uniprotkb:ERF4(gene name synonym)|uniprotkb:Hyperactive Ras suppressor protein 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333465|imex:IM-14275-1776 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YJL127C(gene)|ensemblfungi:YJL127C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016573"(histone acetylation)|go:"GO:0016747"(acyltransferase activity, transferring groups other than amino-acyl groups)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0032931"("histone acetyltransferase activity (H3-K56 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|refseq:NP_012408.1|sgd:S000003663|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR015416(Zinc finger, H2C2-type, histone UAS binding)|mint:P35208 refseq:NP_014531.1|sgd:S000005470|dip:DIP-7228N|mint:P41912|ensemblfungi:YOL110W(gene)|ensemblfungi:YOL110W_mRNA(transcript)|go:"GO:0002178"(palmitoyltransferase complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0031211"(endoplasmic reticulum palmitoyltransferase complex)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|interpro:IPR019383|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:/WoCg6JknSc1f/hiNENAN92iG74559292 rogid:BQ1Foh34E0ylxN2XnzqzluZradc559292 intact-crc:79055150300AC42E|rigid:wHlnZVeAhfUf8b3tTTfKc4HK0ac false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41921 uniprotkb:P31412 intact:EBI-7920|ensemblfungi:YPL091W|uniprotkb:D6W3S6 intact:EBI-20260|uniprotkb:D6VXK7|ensemblfungi:YKL080W psi-mi:gshr_yeast(display_long)|uniprotkb:LPG17W(orf name)|uniprotkb:YPL091W(locus name)|uniprotkb:GLR1(gene name)|psi-mi:GLR1(display_short) psi-mi:vatc_yeast(display_long)|uniprotkb:VMA5(gene name)|psi-mi:VMA5(display_short)|uniprotkb:VAT3(gene name synonym)|uniprotkb:VATC(gene name synonym)|uniprotkb:YKL410(orf name)|uniprotkb:YKL080W(locus name)|uniprotkb:Vacuolar proton pump subunit C(gene name synonym)|uniprotkb:V-ATPase 42 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333476|imex:IM-14275-1777 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015234.1|sgd:S000006012|ensemblfungi:YPL091W(gene)|ensemblfungi:YPL091W_mRNA(transcript)|go:"GO:0004362"("glutathione-disulfide reductase (NADPH) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010731"(protein glutathionylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006322(Glutathione reductase, animal and bacterial)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|rcsb pdb:2HQM|reactome:R-SCE-3299685|reactome:R-SCE-499943|reactome:R-SCE-5628897|go:"GO:0050661"(NADP binding)|mint:P41921|dip:DIP-4020N refseq:NP_012843.1|sgd:S000001563|ensemblfungi:YKL080W(gene)|ensemblfungi:YKL080W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004907(ATPase, V1 complex, subunit C)|interpro:IPR036132|rcsb pdb:1U7L|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4DL0|rcsb pdb:4EFA|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-4701N|mint:P31412 psi-mi:"MI:0469"(intact) crc64:203BBB770120504A crc64:0CD1B814046C377E figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1+gFQ2Tbb89fNCsx7f6JlP5VLBA559292 rogid:NBI0upCB5yxAyMQgccBcLhjZk8s559292 intact-crc:6ED77C8FA1E12CDD|rigid:RkGji1NqN7sZ6X6DVhKLSZHJVu0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41921 uniprotkb:P41921 intact:EBI-7920|ensemblfungi:YPL091W|uniprotkb:D6W3S6 intact:EBI-7920|ensemblfungi:YPL091W|uniprotkb:D6W3S6 psi-mi:gshr_yeast(display_long)|uniprotkb:LPG17W(orf name)|uniprotkb:YPL091W(locus name)|uniprotkb:GLR1(gene name)|psi-mi:GLR1(display_short) psi-mi:gshr_yeast(display_long)|uniprotkb:LPG17W(orf name)|uniprotkb:YPL091W(locus name)|uniprotkb:GLR1(gene name)|psi-mi:GLR1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333487|imex:IM-14275-1778 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015234.1|sgd:S000006012|ensemblfungi:YPL091W(gene)|ensemblfungi:YPL091W_mRNA(transcript)|go:"GO:0004362"("glutathione-disulfide reductase (NADPH) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010731"(protein glutathionylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006322(Glutathione reductase, animal and bacterial)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|rcsb pdb:2HQM|reactome:R-SCE-3299685|reactome:R-SCE-499943|reactome:R-SCE-5628897|go:"GO:0050661"(NADP binding)|mint:P41921|dip:DIP-4020N refseq:NP_015234.1|sgd:S000006012|ensemblfungi:YPL091W(gene)|ensemblfungi:YPL091W_mRNA(transcript)|go:"GO:0004362"("glutathione-disulfide reductase (NADPH) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010731"(protein glutathionylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006322(Glutathione reductase, animal and bacterial)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|rcsb pdb:2HQM|reactome:R-SCE-3299685|reactome:R-SCE-499943|reactome:R-SCE-5628897|go:"GO:0050661"(NADP binding)|mint:P41921|dip:DIP-4020N psi-mi:"MI:0469"(intact) crc64:203BBB770120504A crc64:203BBB770120504A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1+gFQ2Tbb89fNCsx7f6JlP5VLBA559292 rogid:1+gFQ2Tbb89fNCsx7f6JlP5VLBA559292 intact-crc:51AD933652F29971|rigid:aKvJZPknWUSypJJYIqW0rd1Q+EE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25567 uniprotkb:P41940 intact:EBI-18084|uniprotkb:D6VQX8|ensemblfungi:YCL037C intact:EBI-11191|uniprotkb:D6VRU1|ensemblfungi:YDL055C psi-mi:sro9_yeast(display_long)|uniprotkb:SRO9(gene name)|psi-mi:SRO9(display_short)|uniprotkb:YCL037C(locus name)|uniprotkb:YCL37C(orf name)|uniprotkb:Suppressor of RHO3 protein 9(gene name synonym) psi-mi:mpg1_yeast(display_long)|uniprotkb:YDL055C(locus name)|uniprotkb:PSA1(gene name)|psi-mi:PSA1(display_short)|uniprotkb:MPG1(gene name synonym)|uniprotkb:SRB1(gene name synonym)|uniprotkb:VIG9(gene name synonym)|uniprotkb:ATP-mannose-1-phosphate guanylyltransferase(gene name synonym)|uniprotkb:GDP-mannose pyrophosphorylase(gene name synonym)|uniprotkb:NDP-hexose pyrophosphorylase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333498|imex:IM-14275-1779 author score:97.40 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009893.2|sgd:S000000542|ensemblfungi:YCL037C(gene)|ensemblfungi:YCL037C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|dip:DIP-6638N|mint:P25567 ensemblfungi:YDL055C(gene)|ensemblfungi:YDL055C_mRNA(transcript)|go:"GO:0004475"(mannose-1-phosphate guanylyltransferase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006486"(protein glycosylation)|go:"GO:0007049"(cell cycle)|go:"GO:0009298"(GDP-mannose biosynthetic process)|go:"GO:0000032"(cell wall mannoprotein biosynthetic process)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR018357|interpro:IPR029044|refseq:NP_010228.1|sgd:S000002213|mint:P41940|dip:DIP-4322N psi-mi:"MI:0469"(intact) crc64:B1B720D40C7B9914 crc64:DBF1C39BEAE0B776 figure legend:tables S3 and S4|author-confidence:97.40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CouwiBsK7S3Tm6CoBsu3LdWfelg559292 rogid:GRG89tGL6YWXVeYaorJ+bzXzj4E559292 intact-crc:6921C52E6E407147|rigid:JhQnKKekhGzYJaHva3+O4YX37MI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41940 uniprotkb:P32324 intact:EBI-11191|uniprotkb:D6VRU1|ensemblfungi:YDL055C intact:EBI-6333|uniprotkb:Q6JEF7|uniprotkb:D6VT19|ensemblfungi:YDR385W|ensemblfungi:YOR133W psi-mi:mpg1_yeast(display_long)|uniprotkb:YDL055C(locus name)|uniprotkb:PSA1(gene name)|psi-mi:PSA1(display_short)|uniprotkb:MPG1(gene name synonym)|uniprotkb:SRB1(gene name synonym)|uniprotkb:VIG9(gene name synonym)|uniprotkb:ATP-mannose-1-phosphate guanylyltransferase(gene name synonym)|uniprotkb:GDP-mannose pyrophosphorylase(gene name synonym)|uniprotkb:NDP-hexose pyrophosphorylase(gene name synonym) psi-mi:ef2_yeast(display_long)|uniprotkb:EFT1(gene name)|psi-mi:EFT1(display_short)|uniprotkb:YOR133W(locus name)|uniprotkb:O3317(orf name)|uniprotkb:YOR3317W(orf name)|uniprotkb:EFT2(gene name)|psi-mi:EFT2(display_short)|uniprotkb:YDR385W(locus name)|uniprotkb:Translation elongation factor 2(gene name synonym)|uniprotkb:Eukaryotic elongation factor 2(gene name synonym)|uniprotkb:Ribosomal translocase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333509|imex:IM-14275-1780 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDL055C(gene)|ensemblfungi:YDL055C_mRNA(transcript)|go:"GO:0004475"(mannose-1-phosphate guanylyltransferase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006486"(protein glycosylation)|go:"GO:0007049"(cell cycle)|go:"GO:0009298"(GDP-mannose biosynthetic process)|go:"GO:0000032"(cell wall mannoprotein biosynthetic process)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR018357|interpro:IPR029044|refseq:NP_010228.1|sgd:S000002213|mint:P41940|dip:DIP-4322N refseq:NP_010673.1|refseq:NP_014776.1|sgd:S000005659|sgd:S000002793|ensemblfungi:YDR385W(gene)|ensemblfungi:YDR385W_mRNA(transcript)|ensemblfungi:YOR133W(gene)|ensemblfungi:YOR133W_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0019843"(rRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0051087"(chaperone binding)|go:"GO:1990145"(maintenance of translational fidelity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|mint:P32324|dip:DIP-4911N|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|rcsb pdb:1N0U|rcsb pdb:1N0V|rcsb pdb:1U2R|rcsb pdb:1ZM2|rcsb pdb:1ZM3|rcsb pdb:1ZM4|rcsb pdb:1ZM9|rcsb pdb:2E1R|rcsb pdb:2NPF|rcsb pdb:2P8W|rcsb pdb:2P8X|rcsb pdb:2P8Y|rcsb pdb:2P8Z|rcsb pdb:2ZIT|rcsb pdb:3B78|rcsb pdb:3B82|rcsb pdb:3B8H|rcsb pdb:3DNY|rcsb pdb:4V4B|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|reactome:R-SCE-156902|reactome:R-SCE-5358493|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) crc64:DBF1C39BEAE0B776 crc64:FD2F8073CB9B66AA figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GRG89tGL6YWXVeYaorJ+bzXzj4E559292 rogid:mlyt9YKZrGhGbsSlvxNJ0p1C67I559292 intact-crc:BF8245FBD204AFC3|rigid:4Ka5DK7znyxyi0XOp/d3vie/Kro false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41940 uniprotkb:P38636 intact:EBI-11191|uniprotkb:D6VRU1|ensemblfungi:YDL055C intact:EBI-2046026|uniprotkb:D6W0T4|uniprotkb:E9P8W0|ensemblfungi:YNL259C psi-mi:mpg1_yeast(display_long)|uniprotkb:YDL055C(locus name)|uniprotkb:PSA1(gene name)|psi-mi:PSA1(display_short)|uniprotkb:MPG1(gene name synonym)|uniprotkb:SRB1(gene name synonym)|uniprotkb:VIG9(gene name synonym)|uniprotkb:ATP-mannose-1-phosphate guanylyltransferase(gene name synonym)|uniprotkb:GDP-mannose pyrophosphorylase(gene name synonym)|uniprotkb:NDP-hexose pyrophosphorylase(gene name synonym) psi-mi:atx1_yeast(display_long)|uniprotkb:N0840(orf name)|uniprotkb:YNL259C(locus name)|uniprotkb:ATX1(gene name)|psi-mi:ATX1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333520|imex:IM-14275-1781 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDL055C(gene)|ensemblfungi:YDL055C_mRNA(transcript)|go:"GO:0004475"(mannose-1-phosphate guanylyltransferase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006486"(protein glycosylation)|go:"GO:0007049"(cell cycle)|go:"GO:0009298"(GDP-mannose biosynthetic process)|go:"GO:0000032"(cell wall mannoprotein biosynthetic process)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR018357|interpro:IPR029044|refseq:NP_010228.1|sgd:S000002213|mint:P41940|dip:DIP-4322N refseq:NP_014140.1|sgd:S000005203|dip:DIP-813N|mint:P38636|ensemblfungi:YNL259C(gene)|ensemblfungi:YNL259C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006825"(copper ion transport)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|interpro:IPR006121(Heavy metal transport/detoxification protein)|interpro:IPR017969|interpro:IPR036163|rcsb pdb:1CC7|rcsb pdb:1CC8|rcsb pdb:1FD8|rcsb pdb:1FES|rcsb pdb:1UV1|rcsb pdb:1UV2|rcsb pdb:2GGP|rcsb pdb:3K7R|rcsb pdb:5VDE|rcsb pdb:5VDF psi-mi:"MI:0469"(intact) crc64:DBF1C39BEAE0B776 crc64:9BDF0B542F80EA83 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GRG89tGL6YWXVeYaorJ+bzXzj4E559292 rogid:18VKJsTH1VyY1vod4zaFwJYPd+A559292 intact-crc:63BAB7E8AC5C82D1|rigid:rFjQ7Z66XG5VacW9a2308VY+vh4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41940 uniprotkb:P41810 intact:EBI-11191|uniprotkb:D6VRU1|ensemblfungi:YDL055C intact:EBI-4869|uniprotkb:Q03779|uniprotkb:D6VSL9|ensemblfungi:YDR238C psi-mi:mpg1_yeast(display_long)|uniprotkb:YDL055C(locus name)|uniprotkb:PSA1(gene name)|psi-mi:PSA1(display_short)|uniprotkb:MPG1(gene name synonym)|uniprotkb:SRB1(gene name synonym)|uniprotkb:VIG9(gene name synonym)|uniprotkb:ATP-mannose-1-phosphate guanylyltransferase(gene name synonym)|uniprotkb:GDP-mannose pyrophosphorylase(gene name synonym)|uniprotkb:NDP-hexose pyrophosphorylase(gene name synonym) psi-mi:copb_yeast(display_long)|uniprotkb:SEC26(gene name)|psi-mi:SEC26(display_short)|uniprotkb:YDR238C(locus name)|uniprotkb:YD8419.05C(orf name)|uniprotkb:Beta-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333531|imex:IM-14275-1782 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDL055C(gene)|ensemblfungi:YDL055C_mRNA(transcript)|go:"GO:0004475"(mannose-1-phosphate guanylyltransferase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006486"(protein glycosylation)|go:"GO:0007049"(cell cycle)|go:"GO:0009298"(GDP-mannose biosynthetic process)|go:"GO:0000032"(cell wall mannoprotein biosynthetic process)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR018357|interpro:IPR029044|refseq:NP_010228.1|sgd:S000002213|mint:P41940|dip:DIP-4322N sgd:S000002646|refseq:NP_010524.3|dip:DIP-6467N|mint:P41810|ensemblfungi:YDR238C(gene)|ensemblfungi:YDR238C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|reactome:R-SCE-6798695|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:DBF1C39BEAE0B776 crc64:885420DB026BCFA3 figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GRG89tGL6YWXVeYaorJ+bzXzj4E559292 rogid:ZfLp1BUmvVuTiXn7/Zbf/3m6VtE559292 intact-crc:A65C80B60CBD65FD|rigid:Y4ygkdV82JlnVER1rq59eVJxxpQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53278 uniprotkb:P41940 intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C intact:EBI-11191|uniprotkb:D6VRU1|ensemblfungi:YDL055C psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name) psi-mi:mpg1_yeast(display_long)|uniprotkb:YDL055C(locus name)|uniprotkb:PSA1(gene name)|psi-mi:PSA1(display_short)|uniprotkb:MPG1(gene name synonym)|uniprotkb:SRB1(gene name synonym)|uniprotkb:VIG9(gene name synonym)|uniprotkb:ATP-mannose-1-phosphate guanylyltransferase(gene name synonym)|uniprotkb:GDP-mannose pyrophosphorylase(gene name synonym)|uniprotkb:NDP-hexose pyrophosphorylase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333542|imex:IM-14275-1783 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome) ensemblfungi:YDL055C(gene)|ensemblfungi:YDL055C_mRNA(transcript)|go:"GO:0004475"(mannose-1-phosphate guanylyltransferase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006486"(protein glycosylation)|go:"GO:0007049"(cell cycle)|go:"GO:0009298"(GDP-mannose biosynthetic process)|go:"GO:0000032"(cell wall mannoprotein biosynthetic process)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR018357|interpro:IPR029044|refseq:NP_010228.1|sgd:S000002213|mint:P41940|dip:DIP-4322N psi-mi:"MI:0469"(intact) crc64:D482327C9274C026 crc64:DBF1C39BEAE0B776 figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292 rogid:GRG89tGL6YWXVeYaorJ+bzXzj4E559292 intact-crc:50514B9F21349B65|rigid:GRTunQ5LamVPhUf+6BS/Y7LSx/k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53338 uniprotkb:P41940 intact:EBI-2080993|uniprotkb:D6VV65|ensemblfungi:YGR288W intact:EBI-11191|uniprotkb:D6VRU1|ensemblfungi:YDL055C psi-mi:mal13_yeast(display_long)|uniprotkb:MAL13(gene name)|psi-mi:MAL13(display_short)|uniprotkb:MAL1R(gene name synonym)|uniprotkb:G9591(orf name)|uniprotkb:YGR288W(locus name) psi-mi:mpg1_yeast(display_long)|uniprotkb:YDL055C(locus name)|uniprotkb:PSA1(gene name)|psi-mi:PSA1(display_short)|uniprotkb:MPG1(gene name synonym)|uniprotkb:SRB1(gene name synonym)|uniprotkb:VIG9(gene name synonym)|uniprotkb:ATP-mannose-1-phosphate guanylyltransferase(gene name synonym)|uniprotkb:GDP-mannose pyrophosphorylase(gene name synonym)|uniprotkb:NDP-hexose pyrophosphorylase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333553|imex:IM-14275-1784 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011804.1|sgd:S000003520|interpro:IPR020448|interpro:IPR007219(Fungal specific transcription factor)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|mint:P53338|interpro:IPR036864|ensemblfungi:YGR288W(gene)|ensemblfungi:YGR288W_mRNA(transcript)|go:"GO:0000023"(maltose metabolic process)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0044262"(cellular carbohydrate metabolic process) ensemblfungi:YDL055C(gene)|ensemblfungi:YDL055C_mRNA(transcript)|go:"GO:0004475"(mannose-1-phosphate guanylyltransferase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006486"(protein glycosylation)|go:"GO:0007049"(cell cycle)|go:"GO:0009298"(GDP-mannose biosynthetic process)|go:"GO:0000032"(cell wall mannoprotein biosynthetic process)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR018357|interpro:IPR029044|refseq:NP_010228.1|sgd:S000002213|mint:P41940|dip:DIP-4322N psi-mi:"MI:0469"(intact) - crc64:DBF1C39BEAE0B776 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:7MZ3WokwO6lF9sgeqh+39DIgVJs559292 rogid:GRG89tGL6YWXVeYaorJ+bzXzj4E559292 intact-crc:5A7D95AABAA56FE8|rigid:Ixgm1PaX2jm2w6paSTubzjid9oo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41940 uniprotkb:Q10740 intact:EBI-11191|uniprotkb:D6VRU1|ensemblfungi:YDL055C intact:EBI-10175|uniprotkb:D6W1D4|ensemblfungi:YNL045W psi-mi:mpg1_yeast(display_long)|uniprotkb:YDL055C(locus name)|uniprotkb:PSA1(gene name)|psi-mi:PSA1(display_short)|uniprotkb:MPG1(gene name synonym)|uniprotkb:SRB1(gene name synonym)|uniprotkb:VIG9(gene name synonym)|uniprotkb:ATP-mannose-1-phosphate guanylyltransferase(gene name synonym)|uniprotkb:GDP-mannose pyrophosphorylase(gene name synonym)|uniprotkb:NDP-hexose pyrophosphorylase(gene name synonym) psi-mi:lkha4_yeast(display_long)|uniprotkb:LAP2(gene name)|psi-mi:LAP2(display_short)|uniprotkb:Epoxide hydrolase(gene name synonym)|uniprotkb:Leucyl aminopeptidase yscIV(gene name synonym)|uniprotkb:Leukotriene A-4 hydrolase homolog(gene name synonym)|uniprotkb:N2535(orf name)|uniprotkb:YNL045W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333564|imex:IM-14275-1785 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDL055C(gene)|ensemblfungi:YDL055C_mRNA(transcript)|go:"GO:0004475"(mannose-1-phosphate guanylyltransferase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006486"(protein glycosylation)|go:"GO:0007049"(cell cycle)|go:"GO:0009298"(GDP-mannose biosynthetic process)|go:"GO:0000032"(cell wall mannoprotein biosynthetic process)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR018357|interpro:IPR029044|refseq:NP_010228.1|sgd:S000002213|mint:P41940|dip:DIP-4322N refseq:NP_014353.1|sgd:S000004990|go:"GO:0008270"(zinc ion binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0044255"(cellular lipid metabolic process)|ensemblfungi:YNL045W(gene)|ensemblfungi:YNL045W_mRNA(transcript)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004301"(epoxide hydrolase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|go:"GO:0005829"(cytosol)|interpro:IPR012777(Leukotriene A-4 hydrolase/aminopeptidase)|go:"GO:0008237"(metallopeptidase activity)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR015211(Peptidase M1, leukotriene A4 hydrolase, aminopeptidase C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027268|interpro:IPR034015|interpro:IPR038502|interpro:IPR042097|rcsb pdb:2XPZ|rcsb pdb:2XQ0|reactome:R-SCE-2142691|reactome:R-SCE-6798695|reactome:R-SCE-9018676|reactome:R-SCE-9018681|reactome:R-SCE-9018896|reactome:R-SCE-9020265|rcsb pdb:2XPY|reactome:R-SCE-9023661|dip:DIP-4371N|mint:Q10740 psi-mi:"MI:0469"(intact) crc64:DBF1C39BEAE0B776 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GRG89tGL6YWXVeYaorJ+bzXzj4E559292 rogid:CqwX8n+boaHaneIOt/jhsAJngF8559292 intact-crc:F881CE84AFC038F8|rigid:mlGeoRC/e0b+NQhAYz9rQj+wdnI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42838 uniprotkb:P11076 intact:EBI-28396|uniprotkb:D6W0M3|ensemblfungi:YNL323W intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W psi-mi:lem3_yeast(display_long)|uniprotkb:LEM3(gene name)|psi-mi:LEM3(display_short)|uniprotkb:BRE3(gene name synonym)|uniprotkb:Ro-sensitive 3(gene name synonym)|uniprotkb:Brefeldin-A sensitivity protein 3(gene name synonym)|uniprotkb:ROS3(gene name synonym)|uniprotkb:N0333(orf name)|uniprotkb:YNL323W(locus name) psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333575|imex:IM-14275-1786 author score:86.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014076.1|sgd:S000005267|dip:DIP-4598N|mint:P42838|ensemblfungi:YNL323W(gene)|ensemblfungi:YNL323W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044088"(regulation of vacuole organization)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0140331"(aminophospholipid translocation)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|rcsb pdb:7KY5|rcsb pdb:7KY7|rcsb pdb:7KY8|rcsb pdb:7KY9|rcsb pdb:7KYA|rcsb pdb:7KYB|rcsb pdb:7KYC|reactome:R-SCE-6798695 refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 psi-mi:"MI:0469"(intact) crc64:55BDA1F32251B4E6 crc64:796859026AC63CC0 figure legend:tables S3 and S4|author-confidence:86.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YNU4U5F2bWdXZvJYQ9HK0iWX230559292 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 intact-crc:C1ED516668430A5C|rigid:6y1XhiCBtYzfqk5ZhtN88MfoIjI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42838 uniprotkb:P32660 intact:EBI-28396|uniprotkb:D6W0M3|ensemblfungi:YNL323W intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W psi-mi:lem3_yeast(display_long)|uniprotkb:LEM3(gene name)|psi-mi:LEM3(display_short)|uniprotkb:BRE3(gene name synonym)|uniprotkb:Ro-sensitive 3(gene name synonym)|uniprotkb:Brefeldin-A sensitivity protein 3(gene name synonym)|uniprotkb:ROS3(gene name synonym)|uniprotkb:N0333(orf name)|uniprotkb:YNL323W(locus name) psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333586|imex:IM-14275-1787 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014076.1|sgd:S000005267|dip:DIP-4598N|mint:P42838|ensemblfungi:YNL323W(gene)|ensemblfungi:YNL323W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044088"(regulation of vacuole organization)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0140331"(aminophospholipid translocation)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|rcsb pdb:7KY5|rcsb pdb:7KY7|rcsb pdb:7KY8|rcsb pdb:7KY9|rcsb pdb:7KYA|rcsb pdb:7KYB|rcsb pdb:7KYC|reactome:R-SCE-6798695 sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) psi-mi:"MI:0469"(intact) crc64:55BDA1F32251B4E6 crc64:3CC3FBA8ADDE8960 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YNU4U5F2bWdXZvJYQ9HK0iWX230559292 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 intact-crc:4793C86028611093|rigid:K113XbAj8d/ppcLMEzF12rkjy14 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42842 uniprotkb:P32324 intact:EBI-28374|uniprotkb:D6W0N2|ensemblfungi:YNL313C intact:EBI-6333|uniprotkb:Q6JEF7|uniprotkb:D6VT19|ensemblfungi:YDR385W|ensemblfungi:YOR133W psi-mi:emw1_yeast(display_long)|uniprotkb:N0364(orf name)|uniprotkb:YNL313C(locus name)|uniprotkb:EMW1(gene name)|psi-mi:EMW1(display_short) psi-mi:ef2_yeast(display_long)|uniprotkb:EFT1(gene name)|psi-mi:EFT1(display_short)|uniprotkb:YOR133W(locus name)|uniprotkb:O3317(orf name)|uniprotkb:YOR3317W(orf name)|uniprotkb:EFT2(gene name)|psi-mi:EFT2(display_short)|uniprotkb:YDR385W(locus name)|uniprotkb:Translation elongation factor 2(gene name synonym)|uniprotkb:Eukaryotic elongation factor 2(gene name synonym)|uniprotkb:Ribosomal translocase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333597|imex:IM-14275-1788 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014086.1|sgd:S000005257|dip:DIP-6783N|mint:P42842|ensemblfungi:YNL313C(gene)|ensemblfungi:YNL313C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044244 refseq:NP_010673.1|refseq:NP_014776.1|sgd:S000005659|sgd:S000002793|ensemblfungi:YDR385W(gene)|ensemblfungi:YDR385W_mRNA(transcript)|ensemblfungi:YOR133W(gene)|ensemblfungi:YOR133W_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0019843"(rRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0051087"(chaperone binding)|go:"GO:1990145"(maintenance of translational fidelity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|mint:P32324|dip:DIP-4911N|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|rcsb pdb:1N0U|rcsb pdb:1N0V|rcsb pdb:1U2R|rcsb pdb:1ZM2|rcsb pdb:1ZM3|rcsb pdb:1ZM4|rcsb pdb:1ZM9|rcsb pdb:2E1R|rcsb pdb:2NPF|rcsb pdb:2P8W|rcsb pdb:2P8X|rcsb pdb:2P8Y|rcsb pdb:2P8Z|rcsb pdb:2ZIT|rcsb pdb:3B78|rcsb pdb:3B82|rcsb pdb:3B8H|rcsb pdb:3DNY|rcsb pdb:4V4B|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|reactome:R-SCE-156902|reactome:R-SCE-5358493|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:FD2F8073CB9B66AA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:/18IkGF8xyToYJyIpSjbHuleJrM559292 rogid:mlyt9YKZrGhGbsSlvxNJ0p1C67I559292 intact-crc:5F614D3E59D75CF0|rigid:UIExlRcbI+Z4cdl74Ia1O4fER94 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32324 uniprotkb:P42842 intact:EBI-6333|uniprotkb:Q6JEF7|uniprotkb:D6VT19|ensemblfungi:YDR385W|ensemblfungi:YOR133W intact:EBI-28374|uniprotkb:D6W0N2|ensemblfungi:YNL313C psi-mi:ef2_yeast(display_long)|uniprotkb:EFT1(gene name)|psi-mi:EFT1(display_short)|uniprotkb:YOR133W(locus name)|uniprotkb:O3317(orf name)|uniprotkb:YOR3317W(orf name)|uniprotkb:EFT2(gene name)|psi-mi:EFT2(display_short)|uniprotkb:YDR385W(locus name)|uniprotkb:Translation elongation factor 2(gene name synonym)|uniprotkb:Eukaryotic elongation factor 2(gene name synonym)|uniprotkb:Ribosomal translocase(gene name synonym) psi-mi:emw1_yeast(display_long)|uniprotkb:N0364(orf name)|uniprotkb:YNL313C(locus name)|uniprotkb:EMW1(gene name)|psi-mi:EMW1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333608|imex:IM-14275-1789 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010673.1|refseq:NP_014776.1|sgd:S000005659|sgd:S000002793|ensemblfungi:YDR385W(gene)|ensemblfungi:YDR385W_mRNA(transcript)|ensemblfungi:YOR133W(gene)|ensemblfungi:YOR133W_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0019843"(rRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0051087"(chaperone binding)|go:"GO:1990145"(maintenance of translational fidelity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|mint:P32324|dip:DIP-4911N|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|rcsb pdb:1N0U|rcsb pdb:1N0V|rcsb pdb:1U2R|rcsb pdb:1ZM2|rcsb pdb:1ZM3|rcsb pdb:1ZM4|rcsb pdb:1ZM9|rcsb pdb:2E1R|rcsb pdb:2NPF|rcsb pdb:2P8W|rcsb pdb:2P8X|rcsb pdb:2P8Y|rcsb pdb:2P8Z|rcsb pdb:2ZIT|rcsb pdb:3B78|rcsb pdb:3B82|rcsb pdb:3B8H|rcsb pdb:3DNY|rcsb pdb:4V4B|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|reactome:R-SCE-156902|reactome:R-SCE-5358493|reactome:R-SCE-6798695 refseq:NP_014086.1|sgd:S000005257|dip:DIP-6783N|mint:P42842|ensemblfungi:YNL313C(gene)|ensemblfungi:YNL313C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044244 psi-mi:"MI:0469"(intact) crc64:FD2F8073CB9B66AA - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mlyt9YKZrGhGbsSlvxNJ0p1C67I559292 rogid:/18IkGF8xyToYJyIpSjbHuleJrM559292 intact-crc:5F614FEE59D75CF0|rigid:UIExlRcbI+Z4cdl74Ia1O4fER94 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42935 uniprotkb:Q02884 intact:EBI-23459|uniprotkb:D6VUY2|uniprotkb:E9P8V1|ensemblfungi:YGR200C intact:EBI-35277|uniprotkb:D6W3R5|ensemblfungi:YPL101W psi-mi:elp2_yeast(display_long)|uniprotkb:YGR200C(locus name)|uniprotkb:G7725(orf name)|uniprotkb:ELP2(gene name)|psi-mi:ELP2(display_short)|uniprotkb:TOT2(gene name synonym)|uniprotkb:Gamma-toxin target 2(gene name synonym) psi-mi:elp4_yeast(display_long)|uniprotkb:ELP4(gene name)|psi-mi:ELP4(display_short)|uniprotkb:Gamma-toxin target 7(gene name synonym)|uniprotkb:HAT-associated protein 1(gene name synonym)|uniprotkb:YPL101W(locus name)|uniprotkb:HAP1(gene name synonym)|uniprotkb:TOT7(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333619|imex:IM-14275-1790 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003432|refseq:NP_011716.3|dip:DIP-2386N|mint:P42935|ensemblfungi:YGR200C(gene)|ensemblfungi:YGR200C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008017"(microtubule binding)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0015031"(protein transport)|go:"GO:0032447"(protein urmylation)|go:"GO:0033588"(elongator holoenzyme complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037289|rcsb pdb:4XFV|rcsb pdb:5M2N|rcsb pdb:6QK7 refseq:NP_015224.1|sgd:S000006022|mint:Q02884|dip:DIP-6718N|ensemblfungi:YPL101W(gene)|ensemblfungi:YPL101W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR008728(PAXNEB)|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS psi-mi:"MI:0469"(intact) crc64:5371908FE2E6EC0D crc64:276F0D1538EAA8FA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:uBbnUH2xCo3Fu5LlxbrLxO43irk559292 rogid:LLHmiDxhPIIxIElMn9yVWoFnY4Q559292 intact-crc:4E6F81D583683B66|rigid:j0+lfenLMLb/dlrbMdt175vZ1Ow false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3E840 uniprotkb:P42935 intact:EBI-2055307|uniprotkb:D6VPT1|ensemblfungi:YBL071W-A intact:EBI-23459|uniprotkb:D6VUY2|uniprotkb:E9P8V1|ensemblfungi:YGR200C psi-mi:dph3_yeast(display_long)|uniprotkb:DPH3(gene name synonym)|uniprotkb:Kluyveromyces lactis toxin-insensitive protein 11(gene name synonym)|uniprotkb:YBL071W-A(locus name)|uniprotkb:KTI11(gene name)|psi-mi:KTI11(display_short) psi-mi:elp2_yeast(display_long)|uniprotkb:YGR200C(locus name)|uniprotkb:G7725(orf name)|uniprotkb:ELP2(gene name)|psi-mi:ELP2(display_short)|uniprotkb:TOT2(gene name synonym)|uniprotkb:Gamma-toxin target 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333630|imex:IM-14275-1791 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_660100.1|sgd:S000007587|dip:DIP-52225N|mint:Q3E840|ensemblfungi:YBL071W-A(gene)|ensemblfungi:YBL071W-A_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016730"(oxidoreductase activity, acting on iron-sulfur proteins as donors)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|interpro:IPR007872(Zinc finger, DPH-type)|interpro:IPR036671|interpro:IPR044248|rcsb pdb:1YOP|rcsb pdb:1YWS|rcsb pdb:4D4O|rcsb pdb:4D4P|rcsb pdb:4X33|rcsb pdb:5AX2|reactome:R-SCE-5358493 sgd:S000003432|refseq:NP_011716.3|dip:DIP-2386N|mint:P42935|ensemblfungi:YGR200C(gene)|ensemblfungi:YGR200C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008017"(microtubule binding)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0015031"(protein transport)|go:"GO:0032447"(protein urmylation)|go:"GO:0033588"(elongator holoenzyme complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037289|rcsb pdb:4XFV|rcsb pdb:5M2N|rcsb pdb:6QK7 psi-mi:"MI:0469"(intact) crc64:8B27A307831B0ECE crc64:5371908FE2E6EC0D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GwQlZVh0IRJ/OMoCjHic//fuHZE559292 rogid:uBbnUH2xCo3Fu5LlxbrLxO43irk559292 intact-crc:E725B440A080350F|rigid:DdtaEliPVPiYh4j4zOlcJSrMsNk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42945 uniprotkb:Q06679 intact:EBI-1884|uniprotkb:D6VW75|ensemblfungi:YJL109C intact:EBI-35712|uniprotkb:D6VSV7|ensemblfungi:YDR324C psi-mi:utp10_yeast(display_long)|uniprotkb:UTP10(gene name)|psi-mi:UTP10(display_short)|uniprotkb:t-UTP10(gene name synonym)|uniprotkb:U three protein 10(gene name synonym)|uniprotkb:U3 protein 10 required for transcription(gene name synonym)|uniprotkb:J0808(orf name)|uniprotkb:YJL109C(locus name) psi-mi:utp4_yeast(display_long)|uniprotkb:UTP4(gene name)|psi-mi:UTP4(display_short)|uniprotkb:t-UTP4(gene name synonym)|uniprotkb:U three protein 4(gene name synonym)|uniprotkb:U3 protein 4 required for transcription(gene name synonym)|uniprotkb:YDR324C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333641|imex:IM-14275-1792 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012426.1|sgd:S000003645|dip:DIP-6466N|mint:P42945|ensemblfungi:YJL109C(gene)|ensemblfungi:YJL109C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034455"(t-UTP complex)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012954(BP28, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR022125|interpro:IPR040191|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 refseq:NP_010611.3|sgd:S000002732|mint:Q06679|dip:DIP-6436N|ensemblfungi:YDR324C(gene)|ensemblfungi:YDR324C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:064480D1D249B241 crc64:5D1C77899CABB40B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:c7sxmixQnRLFmjuUMDkqZ260ebg559292 rogid:kAD4RO628jpcbjUoQXQbjcGVY88559292 intact-crc:A52E611245C2866A|rigid:jdKFkCRzZa8/0sH1JBp6zjANh/8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54783 uniprotkb:P43497 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 intact:EBI-2044078|uniprotkb:D6VXJ1|ensemblfungi:YKL096W-A psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:cwp2_yeast(display_long)|uniprotkb:LPR1(gene name synonym)|uniprotkb:Low pH resistance protein 1(gene name synonym)|uniprotkb:YKL096BW(orf name)|uniprotkb:YKL444(orf name)|uniprotkb:YKL096W-A(locus name)|uniprotkb:CWP2(gene name)|psi-mi:CWP2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333652|imex:IM-14275-1793 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 refseq:NP_012826.1|sgd:S000001956|interpro:IPR000420(Yeast PIR protein repeat)|mint:P43497|ensemblfungi:YKL096W-A(gene)|ensemblfungi:YKL096W-A_mRNA(transcript)|go:"GO:0005199"(structural constituent of cell wall)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031505"(fungal-type cell wall organization) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 rogid:I1pf6N/8dUODvb5jhcXC902uuew559292 intact-crc:EA229BC2A20F9456|rigid:iXh9HEZIAR/hJG2KQAgy8lyHMe0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P43542 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-2050225|uniprotkb:D6VTG8|ensemblfungi:YFL062W psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:cos4_yeast(display_long)|uniprotkb:YFL062W(locus name)|uniprotkb:COS4(gene name)|psi-mi:COS4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333663|imex:IM-14275-1794 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 sgd:S000001832|refseq:NP_116593.1|dip:DIP-7524N|mint:P43542|ensemblfungi:YFL062W(gene)|ensemblfungi:YFL062W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|interpro:IPR001142(Yeast membrane protein DUP) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:x28b9N8DibMybISEdyKp8e2+zTY559292 intact-crc:983706E851822C16|rigid:kiHS02R//IBV497nKvkoTsu8sCM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43542 uniprotkb:P25361 intact:EBI-2050225|uniprotkb:D6VTG8|ensemblfungi:YFL062W intact:EBI-21909|uniprotkb:D6VR52|ensemblfungi:YCR043C psi-mi:cos4_yeast(display_long)|uniprotkb:YFL062W(locus name)|uniprotkb:COS4(gene name)|psi-mi:COS4(display_short) psi-mi:yct3_yeast(display_long)|uniprotkb:YCR43C(orf name)|uniprotkb:YCR725(orf name)|uniprotkb:YCR043C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333674|imex:IM-14275-1795 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001832|refseq:NP_116593.1|dip:DIP-7524N|mint:P43542|ensemblfungi:YFL062W(gene)|ensemblfungi:YFL062W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|interpro:IPR001142(Yeast membrane protein DUP) sgd:S000000639|refseq:NP_009972.1|mint:P25361|ensemblfungi:YCR043C(gene)|ensemblfungi:YCR043C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0043332"(mating projection tip) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:x28b9N8DibMybISEdyKp8e2+zTY559292 rogid:bEMtsAa5vCsWqGOiXwBK40Pa0xQ559292 intact-crc:CE81B22AA539E74F|rigid:jqt915Jnz6JI0jRaF37vHPIttLg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:P43542 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-2050225|uniprotkb:D6VTG8|ensemblfungi:YFL062W psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:cos4_yeast(display_long)|uniprotkb:YFL062W(locus name)|uniprotkb:COS4(gene name)|psi-mi:COS4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333685|imex:IM-14275-1796 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N sgd:S000001832|refseq:NP_116593.1|dip:DIP-7524N|mint:P43542|ensemblfungi:YFL062W(gene)|ensemblfungi:YFL062W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|interpro:IPR001142(Yeast membrane protein DUP) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:x28b9N8DibMybISEdyKp8e2+zTY559292 intact-crc:8F21043E8CA290DB|rigid:g2sQGtg0jBY4f5vjmAoF2TsCgLg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43542 uniprotkb:P54837 intact:EBI-2050225|uniprotkb:D6VTG8|ensemblfungi:YFL062W intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:cos4_yeast(display_long)|uniprotkb:YFL062W(locus name)|uniprotkb:COS4(gene name)|psi-mi:COS4(display_short) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333696|imex:IM-14275-1797 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001832|refseq:NP_116593.1|dip:DIP-7524N|mint:P43542|ensemblfungi:YFL062W(gene)|ensemblfungi:YFL062W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|interpro:IPR001142(Yeast membrane protein DUP) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:x28b9N8DibMybISEdyKp8e2+zTY559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:D9E8358F7D649272|rigid:c+/UDA2XDfLsQ6V4P4regsn2bQg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22219 uniprotkb:P43550 intact:EBI-20347|uniprotkb:D6VQ98|ensemblfungi:YBR097W intact:EBI-5517|uniprotkb:D6VTH7|ensemblfungi:YFL053W psi-mi:vps15_yeast(display_long)|uniprotkb:VPS15(gene name)|psi-mi:VPS15(display_short)|uniprotkb:GRD8(gene name synonym)|uniprotkb:VPL19(gene name synonym)|uniprotkb:YBR0825(orf name)|uniprotkb:YBR097W(locus name)|uniprotkb:VAC4(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 15(gene name synonym)|uniprotkb:Golgi-retention defective mutant protein 8(gene name synonym) psi-mi:dak2_yeast(display_long)|uniprotkb:DAK2(gene name)|psi-mi:DAK2(display_short)|uniprotkb:Glycerone kinase 2(gene name synonym)|uniprotkb:Triokinase 2(gene name synonym)|uniprotkb:Triose kinase 2(gene name synonym)|uniprotkb:YFL053W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333707|imex:IM-14275-1798 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009655.2|sgd:S000000301|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0071561"(nucleus-vacuole junction)|ensemblfungi:YBR097W(gene)|go:"GO:0106310"(protein serine kinase activity)|ensemblfungi:YBR097W_mRNA(transcript)|go:"GO:0106311"|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001680(WD40 repeat)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR036322|rcsb pdb:3GRE|rcsb pdb:5DFZ|rcsb pdb:5KC2|reactome:R-SCE-1632852|reactome:R-SCE-1660514|reactome:R-SCE-1660516|reactome:R-SCE-1660517|reactome:R-SCE-5668599|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|dip:DIP-814N|mint:P22219 refseq:NP_116602.1|sgd:S000001841|dip:DIP-6539N|mint:P43550|ensemblfungi:YFL053W(gene)|ensemblfungi:YFL053W_mRNA(transcript)|go:"GO:0004371"(glycerone kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0019588"(anaerobic glycerol catabolic process)|go:"GO:0050354"(triokinase activity)|go:"GO:0061610"(glycerol to glycerone phosphate metabolic process)|go:"GO:0097237"(cellular response to toxic substance)|interpro:IPR004006(Dak kinase)|interpro:IPR004007(Dak phosphatase)|interpro:IPR012734(Dihydroxyacetone kinase)|interpro:IPR036117 psi-mi:"MI:0469"(intact) crc64:247EBA5531E41FFB crc64:EE317EC120C0E313 figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:bDKA6IlevNTmtSQqleAbkY7/eAI559292 rogid:n5Po365DD7MsA9UYc4TdBWtAYDw559292 intact-crc:1B9E271F342EA32A|rigid:4LNAdCbnCu4rEIfQ7wGx9uqimU8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:P43555 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-6439|uniprotkb:D6VTI2|ensemblfungi:YFL048C psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:emp47_yeast(display_long)|uniprotkb:YFL048C(locus name)|uniprotkb:EMP47(gene name)|psi-mi:EMP47(display_short)|uniprotkb:47 kDa endomembrane protein(gene name synonym)|uniprotkb:Endosomal P44 protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333718|imex:IM-14275-1799 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 refseq:NP_116606.1|sgd:S000001846|mint:P43555|dip:DIP-7675N|ensemblfungi:YFL048C(gene)|ensemblfungi:YFL048C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016710(L-type lectin, fungi)|interpro:IPR035661|rcsb pdb:2A6Y|rcsb pdb:2A6Z|rcsb pdb:2A70|rcsb pdb:2A71 psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:gq6bd7YuqqXJ+mHOhe1OZ0WU3K4559292 intact-crc:BD9C2779EF0DED9B|rigid:y/wGXAcuru5iIXrhPiDzEM79HqY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43555 uniprotkb:P32798 intact:EBI-6439|uniprotkb:D6VTI2|ensemblfungi:YFL048C intact:EBI-5006|uniprotkb:D6W314|ensemblfungi:YOR316C psi-mi:emp47_yeast(display_long)|uniprotkb:YFL048C(locus name)|uniprotkb:EMP47(gene name)|psi-mi:EMP47(display_short)|uniprotkb:47 kDa endomembrane protein(gene name synonym)|uniprotkb:Endosomal P44 protein(gene name synonym) psi-mi:cot1_yeast(display_long)|uniprotkb:COT1(gene name)|psi-mi:COT1(display_short)|uniprotkb:O6131(orf name)|uniprotkb:YOR316C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333729|imex:IM-14275-1800 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116606.1|sgd:S000001846|mint:P43555|dip:DIP-7675N|ensemblfungi:YFL048C(gene)|ensemblfungi:YFL048C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016710(L-type lectin, fungi)|interpro:IPR035661|rcsb pdb:2A6Y|rcsb pdb:2A6Z|rcsb pdb:2A70|rcsb pdb:2A71 sgd:S000005843|refseq:NP_014961.3|dip:DIP-7554N|mint:P32798|ensemblfungi:YOR316C(gene)|ensemblfungi:YOR316C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006824"(cobalt ion transport)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0015087"(cobalt ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:gq6bd7YuqqXJ+mHOhe1OZ0WU3K4559292 rogid:HEIg6lhS698E9H3BJeESYAipNwA559292 intact-crc:5A26CC3A77AF9836|rigid:9+C0qHXpFWUzxAOhCEvVWVHrBbM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38142 uniprotkb:P43555 intact:EBI-21079|uniprotkb:D6VQN7|intact:EBI-2347460|uniprotkb:Q6B2Y5|ensemblfungi:YBR241C intact:EBI-6439|uniprotkb:D6VTI2|ensemblfungi:YFL048C psi-mi:yb91_yeast(display_long)|uniprotkb:YBR1625(orf name)|uniprotkb:YBR241C(locus name) psi-mi:emp47_yeast(display_long)|uniprotkb:YFL048C(locus name)|uniprotkb:EMP47(gene name)|psi-mi:EMP47(display_short)|uniprotkb:47 kDa endomembrane protein(gene name synonym)|uniprotkb:Endosomal P44 protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333740|imex:IM-14275-1801 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009800.1|sgd:S000000445|mint:P38142|dip:DIP-5363N|ensemblfungi:YBR241C(gene)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|reactome:R-SCE-189200|reactome:R-SCE-196836|reactome:R-SCE-422356|reactome:R-SCE-5653890|reactome:R-SCE-6798695|reactome:R-SCE-8981373|ensemblfungi:YBR241C_mRNA(transcript) refseq:NP_116606.1|sgd:S000001846|mint:P43555|dip:DIP-7675N|ensemblfungi:YFL048C(gene)|ensemblfungi:YFL048C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016710(L-type lectin, fungi)|interpro:IPR035661|rcsb pdb:2A6Y|rcsb pdb:2A6Z|rcsb pdb:2A70|rcsb pdb:2A71 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:B0qgnhfd17hrDGLrJ21KY/FCzTQ559292 rogid:gq6bd7YuqqXJ+mHOhe1OZ0WU3K4559292 intact-crc:7BA22FDCD5289A1D|rigid:05zufAupIIs6sTAaHeMb93rxfjg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43555 uniprotkb:P38166 intact:EBI-6439|uniprotkb:D6VTI2|ensemblfungi:YFL048C intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W psi-mi:emp47_yeast(display_long)|uniprotkb:YFL048C(locus name)|uniprotkb:EMP47(gene name)|psi-mi:EMP47(display_short)|uniprotkb:47 kDa endomembrane protein(gene name synonym)|uniprotkb:Endosomal P44 protein(gene name synonym) psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333751|imex:IM-14275-1802 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116606.1|sgd:S000001846|mint:P43555|dip:DIP-7675N|ensemblfungi:YFL048C(gene)|ensemblfungi:YFL048C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016710(L-type lectin, fungi)|interpro:IPR035661|rcsb pdb:2A6Y|rcsb pdb:2A6Z|rcsb pdb:2A70|rcsb pdb:2A71 ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166 psi-mi:"MI:0469"(intact) - crc64:1BF971749814382C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:gq6bd7YuqqXJ+mHOhe1OZ0WU3K4559292 rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292 intact-crc:A1602FCE29B40825|rigid:w4RvA5haNDEFE54aZMRS/rsRaUE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38310 uniprotkb:P43555 intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W intact:EBI-6439|uniprotkb:D6VTI2|ensemblfungi:YFL048C psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:emp47_yeast(display_long)|uniprotkb:YFL048C(locus name)|uniprotkb:EMP47(gene name)|psi-mi:EMP47(display_short)|uniprotkb:47 kDa endomembrane protein(gene name synonym)|uniprotkb:Endosomal P44 protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333762|imex:IM-14275-1803 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) refseq:NP_116606.1|sgd:S000001846|mint:P43555|dip:DIP-7675N|ensemblfungi:YFL048C(gene)|ensemblfungi:YFL048C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016710(L-type lectin, fungi)|interpro:IPR035661|rcsb pdb:2A6Y|rcsb pdb:2A6Z|rcsb pdb:2A70|rcsb pdb:2A71 psi-mi:"MI:0469"(intact) crc64:7B4E620ABC39A053 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 rogid:gq6bd7YuqqXJ+mHOhe1OZ0WU3K4559292 intact-crc:3699EDD5B99A4F93|rigid:I/If8iC4EAaPbW1FmmOMU1mWzKQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38929 uniprotkb:P43555 intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W intact:EBI-6439|uniprotkb:D6VTI2|ensemblfungi:YFL048C psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:emp47_yeast(display_long)|uniprotkb:YFL048C(locus name)|uniprotkb:EMP47(gene name)|psi-mi:EMP47(display_short)|uniprotkb:47 kDa endomembrane protein(gene name synonym)|uniprotkb:Endosomal P44 protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333773|imex:IM-14275-1804 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 refseq:NP_116606.1|sgd:S000001846|mint:P43555|dip:DIP-7675N|ensemblfungi:YFL048C(gene)|ensemblfungi:YFL048C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016710(L-type lectin, fungi)|interpro:IPR035661|rcsb pdb:2A6Y|rcsb pdb:2A6Z|rcsb pdb:2A70|rcsb pdb:2A71 psi-mi:"MI:0469"(intact) crc64:5BD9ECFF8508F396 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 rogid:gq6bd7YuqqXJ+mHOhe1OZ0WU3K4559292 intact-crc:149F27F4E2C40E56|rigid:OcwUZt1EcAAWqquZj3qCL6eLkhw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43555 uniprotkb:P43621 intact:EBI-6439|uniprotkb:D6VTI2|ensemblfungi:YFL048C intact:EBI-4876|uniprotkb:D6VTT4|ensemblfungi:YFR051C psi-mi:emp47_yeast(display_long)|uniprotkb:YFL048C(locus name)|uniprotkb:EMP47(gene name)|psi-mi:EMP47(display_short)|uniprotkb:47 kDa endomembrane protein(gene name synonym)|uniprotkb:Endosomal P44 protein(gene name synonym) psi-mi:copd_yeast(display_long)|uniprotkb:RET2(gene name)|psi-mi:RET2(display_short)|uniprotkb:YFR051C(locus name)|uniprotkb:Delta-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333784|imex:IM-14275-1805 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116606.1|sgd:S000001846|mint:P43555|dip:DIP-7675N|ensemblfungi:YFL048C(gene)|ensemblfungi:YFL048C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016710(L-type lectin, fungi)|interpro:IPR035661|rcsb pdb:2A6Y|rcsb pdb:2A6Z|rcsb pdb:2A70|rcsb pdb:2A71 sgd:S000001947|refseq:NP_116709.3|dip:DIP-5255N|mint:P43621|ensemblfungi:YFR051C(gene)|ensemblfungi:YFR051C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|rcsb pdb:5FJW|rcsb pdb:5FJX|rcsb pdb:5FJZ|rcsb pdb:5FK0|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - crc64:AA730F046655EE5A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:gq6bd7YuqqXJ+mHOhe1OZ0WU3K4559292 rogid:auvjuT8ffm1R4P3mRKEIWAsynW0559292 intact-crc:47F300BEA2C419C4|rigid:V1cn4Dqc9UAlGJagLUWfMTs7XI8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46989 uniprotkb:P43555 intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C intact:EBI-6439|uniprotkb:D6VTI2|ensemblfungi:YFL048C psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:emp47_yeast(display_long)|uniprotkb:YFL048C(locus name)|uniprotkb:EMP47(gene name)|psi-mi:EMP47(display_short)|uniprotkb:47 kDa endomembrane protein(gene name synonym)|uniprotkb:Endosomal P44 protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333795|imex:IM-14275-1806 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 refseq:NP_116606.1|sgd:S000001846|mint:P43555|dip:DIP-7675N|ensemblfungi:YFL048C(gene)|ensemblfungi:YFL048C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016710(L-type lectin, fungi)|interpro:IPR035661|rcsb pdb:2A6Y|rcsb pdb:2A6Z|rcsb pdb:2A70|rcsb pdb:2A71 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 rogid:gq6bd7YuqqXJ+mHOhe1OZ0WU3K4559292 intact-crc:C5079406C5E6C9F0|rigid:gf5MfW7Kp9VkrjM3Z2vhjBHwUBQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53337 uniprotkb:P43555 intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C intact:EBI-6439|uniprotkb:D6VTI2|ensemblfungi:YFL048C psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:emp47_yeast(display_long)|uniprotkb:YFL048C(locus name)|uniprotkb:EMP47(gene name)|psi-mi:EMP47(display_short)|uniprotkb:47 kDa endomembrane protein(gene name synonym)|uniprotkb:Endosomal P44 protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333806|imex:IM-14275-1807 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 refseq:NP_116606.1|sgd:S000001846|mint:P43555|dip:DIP-7675N|ensemblfungi:YFL048C(gene)|ensemblfungi:YFL048C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016710(L-type lectin, fungi)|interpro:IPR035661|rcsb pdb:2A6Y|rcsb pdb:2A6Z|rcsb pdb:2A70|rcsb pdb:2A71 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 rogid:gq6bd7YuqqXJ+mHOhe1OZ0WU3K4559292 intact-crc:14C11D6D20DF9163|rigid:pGQNAdR9MdSxkKuWA+mFzf49SFU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:P43555 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-6439|uniprotkb:D6VTI2|ensemblfungi:YFL048C psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:emp47_yeast(display_long)|uniprotkb:YFL048C(locus name)|uniprotkb:EMP47(gene name)|psi-mi:EMP47(display_short)|uniprotkb:47 kDa endomembrane protein(gene name synonym)|uniprotkb:Endosomal P44 protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333817|imex:IM-14275-1808 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_116606.1|sgd:S000001846|mint:P43555|dip:DIP-7675N|ensemblfungi:YFL048C(gene)|ensemblfungi:YFL048C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016710(L-type lectin, fungi)|interpro:IPR035661|rcsb pdb:2A6Y|rcsb pdb:2A6Z|rcsb pdb:2A70|rcsb pdb:2A71 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:gq6bd7YuqqXJ+mHOhe1OZ0WU3K4559292 intact-crc:B184B6F04BB52224|rigid:FyiTEr/7oo4gfJOhTqUCSPTckNE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43555 uniprotkb:Q04651 intact:EBI-6439|uniprotkb:D6VTI2|ensemblfungi:YFL048C intact:EBI-27850|uniprotkb:E9PAD9|uniprotkb:D6VZA6|ensemblfungi:YML067C psi-mi:emp47_yeast(display_long)|uniprotkb:YFL048C(locus name)|uniprotkb:EMP47(gene name)|psi-mi:EMP47(display_short)|uniprotkb:47 kDa endomembrane protein(gene name synonym)|uniprotkb:Endosomal P44 protein(gene name synonym) psi-mi:erv41_yeast(display_long)|uniprotkb:YML067C(locus name)|uniprotkb:ERV41(gene name)|psi-mi:ERV41(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333828|imex:IM-14275-1809 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116606.1|sgd:S000001846|mint:P43555|dip:DIP-7675N|ensemblfungi:YFL048C(gene)|ensemblfungi:YFL048C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016710(L-type lectin, fungi)|interpro:IPR035661|rcsb pdb:2A6Y|rcsb pdb:2A6Z|rcsb pdb:2A70|rcsb pdb:2A71 refseq:NP_013644.1|sgd:S000004532|dip:DIP-6791N|mint:Q04651|ensemblfungi:YML067C(gene)|ensemblfungi:YML067C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|rcsb pdb:3ZLC psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:gq6bd7YuqqXJ+mHOhe1OZ0WU3K4559292 rogid:IpGpvBxckHz1ExXTnTsKEHU2su8559292 intact-crc:EB7E8BEB50B7B335|rigid:+Z6IiEX31D7kmPhovcBpoBHHiU0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43555 uniprotkb:Q12016 intact:EBI-6439|uniprotkb:D6VTI2|ensemblfungi:YFL048C intact:EBI-29309|uniprotkb:D6W1T9|ensemblfungi:YOL129W psi-mi:emp47_yeast(display_long)|uniprotkb:YFL048C(locus name)|uniprotkb:EMP47(gene name)|psi-mi:EMP47(display_short)|uniprotkb:47 kDa endomembrane protein(gene name synonym)|uniprotkb:Endosomal P44 protein(gene name synonym) psi-mi:vps68_yeast(display_long)|uniprotkb:YOL129W(locus name)|uniprotkb:VPS68(gene name)|psi-mi:VPS68(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333839|imex:IM-14275-1810 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116606.1|sgd:S000001846|mint:P43555|dip:DIP-7675N|ensemblfungi:YFL048C(gene)|ensemblfungi:YFL048C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016710(L-type lectin, fungi)|interpro:IPR035661|rcsb pdb:2A6Y|rcsb pdb:2A6Z|rcsb pdb:2A70|rcsb pdb:2A71 refseq:NP_014512.1|sgd:S000005489|dip:DIP-1732N|mint:Q12016|ensemblfungi:YOL129W(gene)|ensemblfungi:YOL129W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0034424"(Vps55/Vps68 complex)|interpro:IPR007919(Protein of unknown function UPF0220) psi-mi:"MI:0469"(intact) - crc64:4B21C846AB3BA2A7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:gq6bd7YuqqXJ+mHOhe1OZ0WU3K4559292 rogid:I6sUyfNcLBsFG3OtDUfEqohxLB4559292 intact-crc:83A4C733C2BAFA21|rigid:L779QrmfSOAFkQSERVyInkjIRBk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43555 uniprotkb:Q12270 intact:EBI-6439|uniprotkb:D6VTI2|ensemblfungi:YFL048C intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:emp47_yeast(display_long)|uniprotkb:YFL048C(locus name)|uniprotkb:EMP47(gene name)|psi-mi:EMP47(display_short)|uniprotkb:47 kDa endomembrane protein(gene name synonym)|uniprotkb:Endosomal P44 protein(gene name synonym) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333850|imex:IM-14275-1811 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116606.1|sgd:S000001846|mint:P43555|dip:DIP-7675N|ensemblfungi:YFL048C(gene)|ensemblfungi:YFL048C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016710(L-type lectin, fungi)|interpro:IPR035661|rcsb pdb:2A6Y|rcsb pdb:2A6Z|rcsb pdb:2A70|rcsb pdb:2A71 refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:gq6bd7YuqqXJ+mHOhe1OZ0WU3K4559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:CB51D4AFDC134DF6|rigid:rdQVxVOgL8N+15JHxiB+VZ1EH/0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25656 uniprotkb:P43556 intact:EBI-22014|uniprotkb:D6VR94|ensemblfungi:YCR094W intact:EBI-22845|uniprotkb:D6VTI3|ensemblfungi:YFL047W psi-mi:cdc50_yeast(display_long)|uniprotkb:YCR94W(orf name)|uniprotkb:YCR094W(locus name)|uniprotkb:CDC50(gene name)|psi-mi:CDC50(display_short) psi-mi:rgd2_yeast(display_long)|uniprotkb:RGD2(gene name)|psi-mi:RGD2(display_short)|uniprotkb:YFL047W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333861|imex:IM-14275-1812 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010018.1|sgd:S000000690|dip:DIP-5138N|ensemblfungi:YCR094W(gene)|ensemblfungi:YCR094W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0140331"(aminophospholipid translocation)|go:"GO:1990530"(Cdc50p-Drs2p complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|rcsb pdb:6PSY|rcsb pdb:6ROH|rcsb pdb:6ROI|rcsb pdb:6ROJ|rcsb pdb:7OH4|rcsb pdb:7OH6|rcsb pdb:7OH7|reactome:R-SCE-6798695|rcsb pdb:6PSX|mint:P25656 refseq:NP_428268.1|sgd:S000001847|dip:DIP-4958N|mint:P43556|go:"GO:0005935"(cellular bud neck)|interpro:IPR031160|reactome:R-SCE-8856828|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0032153"(cell division site)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|ensemblfungi:YFL047W(gene)|ensemblfungi:YFL047W_mRNA(transcript)|go:"GO:0000935"(division septum)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip) psi-mi:"MI:0469"(intact) crc64:565575CA402C0C91 crc64:52CF174C5F650157 figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zVi09MNh1hpBUuc5AzasxmCrnKY559292 rogid:TaphLAmYObi9RXMbE2tJDrHtVxA559292 intact-crc:32C915D6235061BB|rigid:P8Je615H32N6P9dayLtwR+KAquI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43556 uniprotkb:P43556 intact:EBI-22845|uniprotkb:D6VTI3|ensemblfungi:YFL047W intact:EBI-22845|uniprotkb:D6VTI3|ensemblfungi:YFL047W psi-mi:rgd2_yeast(display_long)|uniprotkb:RGD2(gene name)|psi-mi:RGD2(display_short)|uniprotkb:YFL047W(locus name) psi-mi:rgd2_yeast(display_long)|uniprotkb:RGD2(gene name)|psi-mi:RGD2(display_short)|uniprotkb:YFL047W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333872|imex:IM-14275-1813 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_428268.1|sgd:S000001847|dip:DIP-4958N|mint:P43556|go:"GO:0005935"(cellular bud neck)|interpro:IPR031160|reactome:R-SCE-8856828|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0032153"(cell division site)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|ensemblfungi:YFL047W(gene)|ensemblfungi:YFL047W_mRNA(transcript)|go:"GO:0000935"(division septum)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip) refseq:NP_428268.1|sgd:S000001847|dip:DIP-4958N|mint:P43556|go:"GO:0005935"(cellular bud neck)|interpro:IPR031160|reactome:R-SCE-8856828|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0032153"(cell division site)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|ensemblfungi:YFL047W(gene)|ensemblfungi:YFL047W_mRNA(transcript)|go:"GO:0000935"(division septum)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip) psi-mi:"MI:0469"(intact) crc64:52CF174C5F650157 crc64:52CF174C5F650157 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TaphLAmYObi9RXMbE2tJDrHtVxA559292 rogid:TaphLAmYObi9RXMbE2tJDrHtVxA559292 intact-crc:9DB1FEBB7310892B|rigid:AtlLSgnqubmAkLsydP2xZGfBGiQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43556 uniprotkb:Q12057 intact:EBI-22845|uniprotkb:D6VTI3|ensemblfungi:YFL047W intact:EBI-29838|uniprotkb:D6W2G4|ensemblfungi:YOR104W psi-mi:rgd2_yeast(display_long)|uniprotkb:RGD2(gene name)|psi-mi:RGD2(display_short)|uniprotkb:YFL047W(locus name) psi-mi:pin2_yeast(display_long)|uniprotkb:PIN2(gene name)|psi-mi:PIN2(display_short)|uniprotkb:YOR3214W(orf name)|uniprotkb:YOR104W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333883|imex:IM-14275-1814 author score:86.47 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_428268.1|sgd:S000001847|dip:DIP-4958N|mint:P43556|go:"GO:0005935"(cellular bud neck)|interpro:IPR031160|reactome:R-SCE-8856828|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0032153"(cell division site)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|ensemblfungi:YFL047W(gene)|ensemblfungi:YFL047W_mRNA(transcript)|go:"GO:0000935"(division septum)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip) sgd:S000005630|refseq:NP_014747.1|dip:DIP-4459N|mint:Q12057|ensemblfungi:YOR104W(gene)|ensemblfungi:YOR104W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|interpro:IPR037504 psi-mi:"MI:0469"(intact) crc64:52CF174C5F650157 - figure legend:tables S3 and S4|author-confidence:86.47|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TaphLAmYObi9RXMbE2tJDrHtVxA559292 rogid:Zk6iUcpP++MEXuhKZ79TMOYQYqM559292 intact-crc:6A673EF4B1C26DCA|rigid:mtWxnZOjgr525p2UD0j2JzytZiA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43561 uniprotkb:P38310 intact:EBI-6891|uniprotkb:D6VTI9|ensemblfungi:YFL041W intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:fet5_yeast(display_long)|uniprotkb:YFL041W(locus name)|uniprotkb:FET5(gene name)|psi-mi:FET5(display_short) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333894|imex:IM-14275-1815 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116612.1|sgd:S000001853|mint:P43561|dip:DIP-6774N|ensemblfungi:YFL041W(gene)|ensemblfungi:YFL041W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006826"(iron ion transport)|go:"GO:0010106"(cellular response to iron ion starvation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0033215"(reductive iron assimilation)|go:"GO:0034755"(iron ion transmembrane transport)|interpro:IPR001117(Multicopper oxidase, type 1)|interpro:IPR002355(Multicopper oxidase, copper-binding site)|interpro:IPR008972(Cupredoxin)|interpro:IPR011706(Multicopper oxidase, type 2)|interpro:IPR011707(Multicopper oxidase, type 3)|interpro:IPR033138|interpro:IPR044130 refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) - crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Po/KJNFIGJj4hdCBkOxRkFEiuqI559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:0B9D0A5044252A22|rigid:4xx9l1U0dc8Y2VImWKX+0a4qWis false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43574 uniprotkb:P23202 intact:EBI-7340|uniprotkb:D6VTK9|ensemblfungi:YFL021W intact:EBI-20138|uniprotkb:D6W0W3|ensemblfungi:YNL229C psi-mi:gat1_yeast(display_long)|uniprotkb:YFL021W(locus name)|uniprotkb:GAT1(gene name)|psi-mi:GAT1(display_short) psi-mi:ure2_yeast(display_long)|uniprotkb:URE2(gene name)|psi-mi:URE2(display_short)|uniprotkb:Disulfide reductase(gene name synonym)|uniprotkb:Glutathione peroxidase(gene name synonym)|uniprotkb:N1165(orf name)|uniprotkb:YNL229C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333905|imex:IM-14275-1816 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116632.1|sgd:S000001873|mint:P43574|dip:DIP-4276N|ensemblfungi:YFL021W(gene)|ensemblfungi:YFL021W_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001080"(nitrogen catabolite activation of transcription from RNA polymerase II promoter)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0036278"(positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0090294"(nitrogen catabolite activation of transcription)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR013860(Protein of unknown function DUF1752, fungi)|interpro:IPR039355|reactome:R-SCE-9018519 refseq:NP_014170.1|sgd:S000005173|ensemblfungi:YNL229C(gene)|ensemblfungi:YNL229C_mRNA(transcript)|mint:P23202|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0010044"(response to aluminum ion)|go:"GO:0032447"(protein urmylation)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR017298(Prion URE2)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:1G6W|rcsb pdb:1G6Y|rcsb pdb:1HQO|rcsb pdb:1JZR|rcsb pdb:1K0A|rcsb pdb:1K0B|rcsb pdb:1K0C|rcsb pdb:1K0D|go:"GO:0003714"(transcription corepressor activity)|dip:DIP-1308N psi-mi:"MI:0469"(intact) - crc64:2C628976034B0F1C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:/vlob/j/dSdgvsFuE993e88Hqzw559292 rogid:jjsWygBsEp8axNurMa3pxPMQJ2k559292 intact-crc:7E5841A8CF6F2536|rigid:JhvnltgLRMYBtACoiQLUKZq4vHg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21304 uniprotkb:P43586 intact:EBI-14328|uniprotkb:D6VYJ9|ensemblfungi:YLR196W intact:EBI-22906|uniprotkb:D6VTN1|ensemblfungi:YFR001W psi-mi:pwp1_yeast(display_long)|uniprotkb:L8167.10(orf name)|uniprotkb:YLR196W(locus name)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short) psi-mi:loc1_yeast(display_long)|uniprotkb:YFR001W(locus name)|uniprotkb:LOC1(gene name)|psi-mi:LOC1(display_short)|uniprotkb:Localization of ASH1 mRNA protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333916|imex:IM-14275-1817 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013297.1|sgd:S000004186|ensemblfungi:YLR196W(gene)|ensemblfungi:YLR196W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR044285|mint:P21304|dip:DIP-4203N refseq:NP_116656.1|sgd:S000001897|dip:DIP-6615N|mint:P43586|ensemblfungi:YFR001W(gene)|ensemblfungi:YFR001W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051028"(mRNA transport)|go:"GO:0101031"(chaperone complex)|interpro:IPR037650|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)") psi-mi:"MI:0469"(intact) crc64:FC0189B289494AB5 crc64:69970294E9C980F9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Q1nPXtlkpIw8JosaiYX0PSVNaSw559292 rogid:9z0K05pOV8o7bqozFWieGjfs/FM559292 intact-crc:AE5B0F55C8401379|rigid:+0jXEm3AgEjKkb9bCr0hkhmkYrg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43586 uniprotkb:P39744 intact:EBI-22906|uniprotkb:D6VTN1|ensemblfungi:YFR001W intact:EBI-29259|uniprotkb:Q08625|uniprotkb:D6W2R2|ensemblfungi:YOR206W psi-mi:loc1_yeast(display_long)|uniprotkb:YFR001W(locus name)|uniprotkb:LOC1(gene name)|psi-mi:LOC1(display_short)|uniprotkb:Localization of ASH1 mRNA protein 1(gene name synonym) psi-mi:noc2_yeast(display_long)|uniprotkb:YOX001(orf name)|uniprotkb:YOR206W(locus name)|uniprotkb:NOC2(gene name)|psi-mi:NOC2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333927|imex:IM-14275-1818 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116656.1|sgd:S000001897|dip:DIP-6615N|mint:P43586|ensemblfungi:YFR001W(gene)|ensemblfungi:YFR001W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051028"(mRNA transport)|go:"GO:0101031"(chaperone complex)|interpro:IPR037650|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)") refseq:NP_014849.3|sgd:S000005732|dip:DIP-4559N|mint:P39744|ensemblfungi:YOR206W(gene)|ensemblfungi:YOR206W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR005343(Protein of unknown function UPF0120) psi-mi:"MI:0469"(intact) crc64:69970294E9C980F9 crc64:48C3B9AE076B9B8F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9z0K05pOV8o7bqozFWieGjfs/FM559292 rogid:d5I8KJOSG63bZ/Pt+XvKdy/SWws559292 intact-crc:B8280EB2BBA72511|rigid:It1Pz+JU2zdRV+KPtiTvvVTXa54 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53874 uniprotkb:P43586 intact:EBI-19873|uniprotkb:D6W101|ensemblfungi:YNL186W intact:EBI-22906|uniprotkb:D6VTN1|ensemblfungi:YFR001W psi-mi:ubp10_yeast(display_long)|uniprotkb:UBP10(gene name)|psi-mi:UBP10(display_short)|uniprotkb:YNL186W(locus name)|uniprotkb:N1619(orf name)|uniprotkb:Ubiquitin-specific-processing protease 10(gene name synonym)|uniprotkb:Deubiquitinating enzyme 10(gene name synonym)|uniprotkb:Disrupter of telomere silencing protein 4(gene name synonym)|uniprotkb:Ubiquitin thioesterase 10(gene name synonym)|uniprotkb:DOT4(gene name synonym) psi-mi:loc1_yeast(display_long)|uniprotkb:YFR001W(locus name)|uniprotkb:LOC1(gene name)|psi-mi:LOC1(display_short)|uniprotkb:Localization of ASH1 mRNA protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333938|imex:IM-14275-1819 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014213.2|sgd:S000005130|ensemblfungi:YNL186W(gene)|ensemblfungi:YNL186W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0043596"(nuclear replication fork)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|rcsb pdb:6RR0|dip:DIP-6664N|mint:P53874 refseq:NP_116656.1|sgd:S000001897|dip:DIP-6615N|mint:P43586|ensemblfungi:YFR001W(gene)|ensemblfungi:YFR001W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051028"(mRNA transport)|go:"GO:0101031"(chaperone complex)|interpro:IPR037650|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)") psi-mi:"MI:0469"(intact) - crc64:69970294E9C980F9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Z1rRAI9RLgHeGd7QwLbrf51v5LY559292 rogid:9z0K05pOV8o7bqozFWieGjfs/FM559292 intact-crc:10E0F925662618A4|rigid:3LvGCCYSO7v5RiLheJIAXnnSoIs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06205 uniprotkb:P43586 intact:EBI-6956|uniprotkb:D6VZ83|ensemblfungi:YLR449W intact:EBI-22906|uniprotkb:D6VTN1|ensemblfungi:YFR001W psi-mi:fkbp4_yeast(display_long)|uniprotkb:FPR4(gene name)|psi-mi:FPR4(display_short)|uniprotkb:YLR449W(locus name)|uniprotkb:L9324.3(orf name)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Histone proline isomerase(gene name synonym) psi-mi:loc1_yeast(display_long)|uniprotkb:YFR001W(locus name)|uniprotkb:LOC1(gene name)|psi-mi:LOC1(display_short)|uniprotkb:Localization of ASH1 mRNA protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333949|imex:IM-14275-1820 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004441|refseq:NP_013554.3|dip:DIP-909N|mint:Q06205|ensemblfungi:YLR449W(gene)|ensemblfungi:YLR449W_mRNA(transcript)|go:"GO:0000412"(histone peptidyl-prolyl isomerization)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR023566|interpro:IPR041232|rcsb pdb:4BF8 refseq:NP_116656.1|sgd:S000001897|dip:DIP-6615N|mint:P43586|ensemblfungi:YFR001W(gene)|ensemblfungi:YFR001W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051028"(mRNA transport)|go:"GO:0101031"(chaperone complex)|interpro:IPR037650|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)") psi-mi:"MI:0469"(intact) crc64:CF90C6714F04572E crc64:69970294E9C980F9 figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rDmDSGEgRbtgkLBoJTzmzxxY7B4559292 rogid:9z0K05pOV8o7bqozFWieGjfs/FM559292 intact-crc:F9611562D373CF26|rigid:/ZxSIC4bxrpICNxQxfRXQVVA3hg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08235 uniprotkb:P43586 intact:EBI-3775|uniprotkb:D6W1Z1|ensemblfungi:YOL077C intact:EBI-22906|uniprotkb:D6VTN1|ensemblfungi:YFR001W psi-mi:brx1_yeast(display_long)|uniprotkb:YOL077C(locus name)|uniprotkb:BRX1(gene name)|psi-mi:BRX1(display_short) psi-mi:loc1_yeast(display_long)|uniprotkb:YFR001W(locus name)|uniprotkb:LOC1(gene name)|psi-mi:LOC1(display_short)|uniprotkb:Localization of ASH1 mRNA protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333960|imex:IM-14275-1821 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014565.2|sgd:S000005437|dip:DIP-6317N|mint:Q08235|ensemblfungi:YOL077C(gene)|ensemblfungi:YOL077C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000464"("endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000465"("exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR007109(Brix)|interpro:IPR026532|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5 refseq:NP_116656.1|sgd:S000001897|dip:DIP-6615N|mint:P43586|ensemblfungi:YFR001W(gene)|ensemblfungi:YFR001W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051028"(mRNA transport)|go:"GO:0101031"(chaperone complex)|interpro:IPR037650|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)") psi-mi:"MI:0469"(intact) crc64:31466853EF0E7301 crc64:69970294E9C980F9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mPR6HWKwM6RNCRE/vezsYlCmEGY559292 rogid:9z0K05pOV8o7bqozFWieGjfs/FM559292 intact-crc:A6F48023E77E3637|rigid:bdIZnAoIdvk3Z9s6ZqqLFSgs860 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43587 uniprotkb:P36047 intact:EBI-22913|uniprotkb:D6VTN3|ensemblfungi:YFR003C intact:EBI-16783|ensemblfungi:YKL193C|uniprotkb:D6VX07 psi-mi:ypi1_yeast(display_long)|uniprotkb:YFR003C(locus name)|uniprotkb:YPI1(gene name)|psi-mi:YPI1(display_short) psi-mi:sds22_yeast(display_long)|uniprotkb:YKL193C(locus name)|uniprotkb:SDS22(gene name)|psi-mi:SDS22(display_short)|uniprotkb:EGP1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333971|imex:IM-14275-1822 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116658.1|sgd:S000001899|dip:DIP-5442N|mint:P43587|ensemblfungi:YFR003C(gene)|ensemblfungi:YFR003C_mRNA(transcript)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006873"(cellular ion homeostasis)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1900180"(regulation of protein localization to nucleus)|interpro:IPR011107(Protein phosphatase inhibitor) interpro:IPR032675|interpro:IPR003591(Leucine-rich repeat, typical subtype)|ensemblfungi:YKL193C(gene)|ensemblfungi:YKL193C_mRNA(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR001611(Leucine-rich repeat)|refseq:NP_012728.1|sgd:S000001676|dip:DIP-2378N|mint:P36047 psi-mi:"MI:0469"(intact) crc64:E191184DCD5EF8A1 crc64:1EF434C7276ABAEA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9O1nEkPevKE4PL5c7cu+WdqATL8559292 rogid:0EB+IWHQJapt77CfEgNmk733koU559292 intact-crc:7212D5B659C6DB36|rigid:YMJLsDFxbkz58clDEj8So731BQA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32660 uniprotkb:P43603 intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W intact:EBI-22980|uniprotkb:D6VTQ4|ensemblfungi:YFR024C-A psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:lsb3_yeast(display_long)|uniprotkb:LSB3(gene name)|psi-mi:LSB3(display_short)|uniprotkb:YFR024C(orf name)|uniprotkb:YFR024C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333982|imex:IM-14275-1823 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) sgd:S000002968|refseq:NP_219497.4|dip:DIP-6259N|mint:P43603|ensemblfungi:YFR024C-A(gene)|ensemblfungi:YFR024C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:1OOT|rcsb pdb:1SSH psi-mi:"MI:0469"(intact) crc64:3CC3FBA8ADDE8960 crc64:F486C787B5771AAC figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 rogid:zKMZQRpG4d/at/NecQDyEi/kVKg559292 intact-crc:9FAFA947D95FC995|rigid:eo2xwJYnhA8S2rHdwv3P1QQoPas false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32793 uniprotkb:P43603 intact:EBI-24460|uniprotkb:D3DKW1|ensemblfungi:YHR016C intact:EBI-22980|uniprotkb:D6VTQ4|ensemblfungi:YFR024C-A psi-mi:ysc84_yeast(display_long)|uniprotkb:YSC84(gene name)|psi-mi:YSC84(display_short)|uniprotkb:LSB4(gene name synonym)|uniprotkb:LAS seventeen-binding protein 4(gene name synonym)|uniprotkb:YHR016C(locus name) psi-mi:lsb3_yeast(display_long)|uniprotkb:LSB3(gene name)|psi-mi:LSB3(display_short)|uniprotkb:YFR024C(orf name)|uniprotkb:YFR024C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6333993|imex:IM-14275-1824 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011880.1|sgd:S000001058|dip:DIP-2026N|mint:P32793|ensemblfungi:YHR016C(gene)|ensemblfungi:YHR016C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:2A08 sgd:S000002968|refseq:NP_219497.4|dip:DIP-6259N|mint:P43603|ensemblfungi:YFR024C-A(gene)|ensemblfungi:YFR024C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:1OOT|rcsb pdb:1SSH psi-mi:"MI:0469"(intact) crc64:DE42E8ECF5B83C92 crc64:F486C787B5771AAC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hirm/OlqdPxvJNPbha68BSFIvmQ559292 rogid:zKMZQRpG4d/at/NecQDyEi/kVKg559292 intact-crc:F5624B2A24087C21|rigid:R8pjxQemMdqoLMS4NXpZfJUH2mE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43603 uniprotkb:P43603 intact:EBI-22980|uniprotkb:D6VTQ4|ensemblfungi:YFR024C-A intact:EBI-22980|uniprotkb:D6VTQ4|ensemblfungi:YFR024C-A psi-mi:lsb3_yeast(display_long)|uniprotkb:LSB3(gene name)|psi-mi:LSB3(display_short)|uniprotkb:YFR024C(orf name)|uniprotkb:YFR024C-A(locus name) psi-mi:lsb3_yeast(display_long)|uniprotkb:LSB3(gene name)|psi-mi:LSB3(display_short)|uniprotkb:YFR024C(orf name)|uniprotkb:YFR024C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334004|imex:IM-14275-1825 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002968|refseq:NP_219497.4|dip:DIP-6259N|mint:P43603|ensemblfungi:YFR024C-A(gene)|ensemblfungi:YFR024C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:1OOT|rcsb pdb:1SSH sgd:S000002968|refseq:NP_219497.4|dip:DIP-6259N|mint:P43603|ensemblfungi:YFR024C-A(gene)|ensemblfungi:YFR024C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:1OOT|rcsb pdb:1SSH psi-mi:"MI:0469"(intact) crc64:F486C787B5771AAC crc64:F486C787B5771AAC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zKMZQRpG4d/at/NecQDyEi/kVKg559292 rogid:zKMZQRpG4d/at/NecQDyEi/kVKg559292 intact-crc:ADEAC7FF3C37442E|rigid:mJIl1BGotMFDGU4tKTOkGMwOODk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08412 uniprotkb:P43603 intact:EBI-37580|uniprotkb:D6W2A8|ensemblfungi:YOR042W intact:EBI-22980|uniprotkb:D6VTQ4|ensemblfungi:YFR024C-A psi-mi:cue5_yeast(display_long)|uniprotkb:YOR042W(locus name)|uniprotkb:CUE5(gene name)|psi-mi:CUE5(display_short)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 5(gene name synonym) psi-mi:lsb3_yeast(display_long)|uniprotkb:LSB3(gene name)|psi-mi:LSB3(display_short)|uniprotkb:YFR024C(orf name)|uniprotkb:YFR024C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334015|imex:IM-14275-1826 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014685.1|sgd:S000005568|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|mint:Q08412|interpro:IPR041807|ensemblfungi:YOR042W(gene)|ensemblfungi:YOR042W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043130"(ubiquitin binding)|reactome:R-SCE-6798695 sgd:S000002968|refseq:NP_219497.4|dip:DIP-6259N|mint:P43603|ensemblfungi:YFR024C-A(gene)|ensemblfungi:YFR024C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:1OOT|rcsb pdb:1SSH psi-mi:"MI:0469"(intact) crc64:0D455F9AD637AC8D crc64:F486C787B5771AAC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:bUu2kNMFibdM8RUj460pMdBr2UA559292 rogid:zKMZQRpG4d/at/NecQDyEi/kVKg559292 intact-crc:B4BAA14705556B1E|rigid:b9iLM7Dx3e0+LPVASI8JtWHgHCo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43612 uniprotkb:P38009 intact:EBI-16370|ensemblfungi:YFR040W|uniprotkb:Q96VG4|uniprotkb:D6VTS3 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 psi-mi:sa155_yeast(display_long)|uniprotkb:SAP155(gene name)|psi-mi:SAP155(display_short)|uniprotkb:YFR040W(locus name) psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334026|imex:IM-14275-1827 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YFR040W(gene)|ensemblfungi:YFR040W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|reactome:R-SCE-204005|refseq:NP_116698.3|sgd:S000001936|dip:DIP-5852N|mint:P43612 refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N psi-mi:"MI:0469"(intact) crc64:50CDC17130333022 crc64:8ABA71761B512242 figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:OX+DqsaQW7F5rHzNB2R69wYu6YE559292 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 intact-crc:F969A93197AF8F18|rigid:KQAeqzgVDVKsF0P4oqWzzsttKF0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43613 uniprotkb:P10127 intact:EBI-23020|uniprotkb:D6VTS4|ensemblfungi:YFR041C intact:EBI-2233|uniprotkb:D6VV79|ensemblfungi:YGL256W psi-mi:erj5_yeast(display_long)|uniprotkb:YFR041C(locus name)|uniprotkb:ERJ5(gene name)|psi-mi:ERJ5(display_short) psi-mi:adh4_yeast(display_long)|uniprotkb:ADH4(gene name)|psi-mi:ADH4(display_short)|uniprotkb:YGL256W(locus name)|uniprotkb:NRC465(orf name)|uniprotkb:ZRG5(gene name synonym)|uniprotkb:Alcohol dehydrogenase IV(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334037|imex:IM-14275-1828 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001937|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|refseq:NP_116699.3|mint:P43613|interpro:IPR036869|ensemblfungi:YFR041C(gene)|ensemblfungi:YFR041C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0016021"(integral component of membrane) refseq:NP_011258.2|sgd:S000003225|dip:DIP-4812N|mint:P10127|ensemblfungi:YGL256W(gene)|ensemblfungi:YGL256W_mRNA(transcript)|go:"GO:0000947"(amino acid catabolic process to alcohol via Ehrlich pathway)|go:"GO:0004022"("alcohol dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006113"(fermentation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001670(Iron-containing alcohol dehydrogenase)|interpro:IPR018211|interpro:IPR039697 psi-mi:"MI:0469"(intact) - crc64:7DFFD43830FB269B figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dnaqwCIoVzjAovDVEk2i0vQDMg4559292 rogid:fbgaUT1lKT6O6lYODaI0xuqspzM559292 intact-crc:887E144F1DFC297B|rigid:OjuN+9s6OrfDyzZ2fvwXs96XlUI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43639 uniprotkb:P15790 intact:EBI-9563|uniprotkb:Q9URG5|ensemblfungi:YGL019W|uniprotkb:D6VUB8 intact:EBI-9533|ensemblfungi:YIL035C|uniprotkb:D6VVP7 psi-mi:csk2b_yeast(display_long)|uniprotkb:CKB1(gene name)|psi-mi:CKB1(display_short)|uniprotkb:YGL019W(locus name) psi-mi:csk21_yeast(display_long)|uniprotkb:YIL035C(locus name)|uniprotkb:CKA1(gene name)|psi-mi:CKA1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334048|imex:IM-14275-1829 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL019W(gene)|ensemblfungi:YGL019W_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0034456"(UTP-C complex)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR035991|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|refseq:NP_011496.3|sgd:S000002987|mint:P43639|dip:DIP-282N refseq:NP_012229.1|sgd:S000001297|ensemblfungi:YIL035C(gene)|ensemblfungi:YIL035C_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007535"(donor selection)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0034456"(UTP-C complex)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:4FI1|rcsb pdb:4JQE|rcsb pdb:4JR7|rcsb pdb:4LFI|rcsb pdb:4MWH|reactome:R-SCE-2514853|reactome:R-SCE-6804756|reactome:R-SCE-8934903|reactome:R-SCE-8948751|mint:P15790|dip:DIP-48N psi-mi:"MI:0469"(intact) crc64:9ACA8D285E6990AF crc64:6A1A7F1BF47250C9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:etfQ7p1F805HcUhV/Uiv9TPtejU559292 rogid:SNrrYvyWdzd6bAyvluPlZqs5WJw559292 intact-crc:19BBBEBE2FA69930|rigid:CBVMW3krEAcKWK84ijWYT8wM2UY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43639 uniprotkb:P19454 intact:EBI-9563|uniprotkb:Q9URG5|ensemblfungi:YGL019W|uniprotkb:D6VUB8 intact:EBI-9548|ensemblfungi:YOR061W|uniprotkb:D6W2C4 psi-mi:csk2b_yeast(display_long)|uniprotkb:CKB1(gene name)|psi-mi:CKB1(display_short)|uniprotkb:YGL019W(locus name) psi-mi:csk22_yeast(display_long)|uniprotkb:CKA2(gene name)|psi-mi:CKA2(display_short)|uniprotkb:YOR29-12(orf name)|uniprotkb:YOR061W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334059|imex:IM-14275-1830 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL019W(gene)|ensemblfungi:YGL019W_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0034456"(UTP-C complex)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR035991|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|refseq:NP_011496.3|sgd:S000002987|mint:P43639|dip:DIP-282N ensemblfungi:YOR061W(gene)|ensemblfungi:YOR061W_mRNA(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007535"(donor selection)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0034456"(UTP-C complex)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-2514853|reactome:R-SCE-6804756|reactome:R-SCE-8934903|reactome:R-SCE-8948751|refseq:NP_014704.1|sgd:S000005587|mint:P19454|dip:DIP-1038N psi-mi:"MI:0469"(intact) crc64:9ACA8D285E6990AF crc64:30E214BD852824D0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:etfQ7p1F805HcUhV/Uiv9TPtejU559292 rogid:E39eioYivVEqVSUhL99a2iGvisg559292 intact-crc:D00ADB20ED53220F|rigid:LTXHUvkEIYJNbSvfGCKF2WAFdEU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38930 uniprotkb:P43639 intact:EBI-9578|ensemblfungi:YOR039W|uniprotkb:D6W2A6 intact:EBI-9563|uniprotkb:Q9URG5|ensemblfungi:YGL019W|uniprotkb:D6VUB8 psi-mi:csk2c_yeast(display_long)|uniprotkb:CKB2(gene name)|psi-mi:CKB2(display_short)|uniprotkb:OR26.32(orf name)|uniprotkb:YOR039W(locus name) psi-mi:csk2b_yeast(display_long)|uniprotkb:CKB1(gene name)|psi-mi:CKB1(display_short)|uniprotkb:YGL019W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334070|imex:IM-14275-1831 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR039W(gene)|ensemblfungi:YOR039W_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0032545"(CURI complex)|go:"GO:0034456"(UTP-C complex)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|reactome:R-SCE-2514853|reactome:R-SCE-6798695|reactome:R-SCE-6804756|reactome:R-SCE-8934903|reactome:R-SCE-8948751|refseq:NP_014682.1|sgd:S000005565|mint:P38930|dip:DIP-262N ensemblfungi:YGL019W(gene)|ensemblfungi:YGL019W_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0034456"(UTP-C complex)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR035991|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|refseq:NP_011496.3|sgd:S000002987|mint:P43639|dip:DIP-282N psi-mi:"MI:0469"(intact) crc64:D6060CB3D70B19A4 crc64:9ACA8D285E6990AF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:X+0JSYVQigL0wSbWYCkorc8jqpw559292 rogid:etfQ7p1F805HcUhV/Uiv9TPtejU559292 intact-crc:27E0248DC109F1B1|rigid:kkQkXXfzttzNEY0BA5E94cRu2LY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46673 uniprotkb:P35729 intact:EBI-12345|ensemblfungi:YJR042W|uniprotkb:D6VWL3 intact:EBI-11713|ensemblfungi:YKL057C|uniprotkb:P35730|uniprotkb:D6VXN0 psi-mi:nup85_yeast(display_long)|uniprotkb:NUP85(gene name)|psi-mi:NUP85(display_short)|uniprotkb:RAT9(gene name synonym)|uniprotkb:YJR042W(locus name)|uniprotkb:J1624(orf name)|uniprotkb:Nuclear pore protein NUP85(gene name synonym) psi-mi:nu120_yeast(display_long)|uniprotkb:NUP120(gene name)|psi-mi:NUP120(display_short)|uniprotkb:RAT2(gene name synonym)|uniprotkb:YKL057C(locus name)|uniprotkb:YKL314(orf name)|uniprotkb:YKL313(orf name)|uniprotkb:Nuclear pore protein NUP120(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334081|imex:IM-14275-1832 author score:93.51 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YJR042W(gene)|ensemblfungi:YJR042W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR011502(Nucleoporin, Nup85-like)|rcsb pdb:3EWE|rcsb pdb:3F3F|rcsb pdb:3F3G|rcsb pdb:3F3P|rcsb pdb:4XMM|rcsb pdb:4XMN|rcsb pdb:6X08|refseq:NP_012576.1|sgd:S000003803|mint:P46673|dip:DIP-5818N ensemblfungi:YKL057C(gene)|ensemblfungi:YKL057C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR021717|rcsb pdb:3F7F|go:"GO:0031509"(subtelomeric heterochromatin assembly)|rcsb pdb:3H7N|rcsb pdb:3HXR|rcsb pdb:4XMM|rcsb pdb:4XMN|rcsb pdb:6X06|refseq:NP_012866.1|sgd:S000001540|mint:P35729|dip:DIP-2721N psi-mi:"MI:0469"(intact) crc64:4C0A4AD3DB57A023 crc64:D4655E6116C54503 figure legend:tables S3 and S4|author-confidence:93.51|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XmACeptHS3SlfgccMUpRYxEA3sI559292 rogid:8A1GtKeq+kjBvl1iuUd6rIx7yLo559292 intact-crc:D3EC4B413C25A4C4|rigid:BRwSzCY+YFKCWI079At/OIgru9g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46673 uniprotkb:P40368 intact:EBI-12345|ensemblfungi:YJR042W|uniprotkb:D6VWL3 intact:EBI-12331|ensemblfungi:YJL061W|uniprotkb:D6VWC1 psi-mi:nup85_yeast(display_long)|uniprotkb:NUP85(gene name)|psi-mi:NUP85(display_short)|uniprotkb:RAT9(gene name synonym)|uniprotkb:YJR042W(locus name)|uniprotkb:J1624(orf name)|uniprotkb:Nuclear pore protein NUP85(gene name synonym) psi-mi:nup82_yeast(display_long)|uniprotkb:NUP82(gene name)|psi-mi:NUP82(display_short)|uniprotkb:YJL061W(locus name)|uniprotkb:J1135(orf name)|uniprotkb:HRB187(orf name)|uniprotkb:Nuclear pore protein NUP82(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334092|imex:IM-14275-1833 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YJR042W(gene)|ensemblfungi:YJR042W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR011502(Nucleoporin, Nup85-like)|rcsb pdb:3EWE|rcsb pdb:3F3F|rcsb pdb:3F3G|rcsb pdb:3F3P|rcsb pdb:4XMM|rcsb pdb:4XMN|rcsb pdb:6X08|refseq:NP_012576.1|sgd:S000003803|mint:P46673|dip:DIP-5818N refseq:NP_012474.1|sgd:S000003597|ensemblfungi:YJL061W(gene)|ensemblfungi:YJL061W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|interpro:IPR037700|rcsb pdb:3PBP|rcsb pdb:3TKN|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|mint:P40368|dip:DIP-913N psi-mi:"MI:0469"(intact) crc64:4C0A4AD3DB57A023 crc64:C379B5E111E26B50 figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XmACeptHS3SlfgccMUpRYxEA3sI559292 rogid:g1+jqOMmde8phrNI9H7nFlXwjH0559292 intact-crc:60ECE13CBA5B3956|rigid:QcbcHwhtZHN9JhNK1QUxkgh/nsQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P49687 uniprotkb:P46673 intact:EBI-11730|ensemblfungi:YGL092W|uniprotkb:D6VU53 intact:EBI-12345|ensemblfungi:YJR042W|uniprotkb:D6VWL3 psi-mi:nu145_yeast(display_long)|uniprotkb:YGL092W(locus name)|uniprotkb:NUP145(gene name)|psi-mi:NUP145(display_short)|uniprotkb:RAT10(gene name synonym)|uniprotkb:Nuclear pore protein NUP145(gene name synonym) psi-mi:nup85_yeast(display_long)|uniprotkb:NUP85(gene name)|psi-mi:NUP85(display_short)|uniprotkb:RAT9(gene name synonym)|uniprotkb:YJR042W(locus name)|uniprotkb:J1624(orf name)|uniprotkb:Nuclear pore protein NUP85(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334103|imex:IM-14275-1834 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL092W(gene)|ensemblfungi:YGL092W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003723"(RNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|rcsb pdb:3BG0|rcsb pdb:3BG1|rcsb pdb:3IKO|rcsb pdb:3JRO|rcsb pdb:3JRP|rcsb pdb:3KEP|rcsb pdb:3KES|rcsb pdb:4XMM|rcsb pdb:4XMN|go:"GO:0031509"(subtelomeric heterochromatin assembly)|refseq:NP_011423.1|sgd:S000003060|mint:P49687|dip:DIP-2074N ensemblfungi:YJR042W(gene)|ensemblfungi:YJR042W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR011502(Nucleoporin, Nup85-like)|rcsb pdb:3EWE|rcsb pdb:3F3F|rcsb pdb:3F3G|rcsb pdb:3F3P|rcsb pdb:4XMM|rcsb pdb:4XMN|rcsb pdb:6X08|refseq:NP_012576.1|sgd:S000003803|mint:P46673|dip:DIP-5818N psi-mi:"MI:0469"(intact) crc64:59399D86BB553030 crc64:4C0A4AD3DB57A023 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IUF7IKaLKMDpFCcuLTjLBB7rD9U559292 rogid:XmACeptHS3SlfgccMUpRYxEA3sI559292 intact-crc:FD5559993FB4986A|rigid:vdhbNead91WUk55cPRGfRAlccwM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46675 uniprotkb:P46675 intact:EBI-18471|uniprotkb:D6VY47|ensemblfungi:YLR045C intact:EBI-18471|uniprotkb:D6VY47|ensemblfungi:YLR045C psi-mi:stu2_yeast(display_long)|uniprotkb:STU2(gene name)|psi-mi:STU2(display_short)|uniprotkb:YLR045C(locus name)|uniprotkb:L2108(orf name)|uniprotkb:Suppressor of tubulin 2(gene name synonym) psi-mi:stu2_yeast(display_long)|uniprotkb:STU2(gene name)|psi-mi:STU2(display_short)|uniprotkb:YLR045C(locus name)|uniprotkb:L2108(orf name)|uniprotkb:Suppressor of tubulin 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334114|imex:IM-14275-1835 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005938"(cell cortex)|refseq:NP_013146.1|sgd:S000004035|ensemblfungi:YLR045C(gene)|ensemblfungi:YLR045C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005816"(spindle pole body)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0061863"(microtubule plus end polymerase)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR034085|rcsb pdb:2QK1|rcsb pdb:4FFB|rcsb pdb:4U3J|rcsb pdb:6BL7|rcsb pdb:7KDF|dip:DIP-2462N|mint:P46675 go:"GO:0005938"(cell cortex)|refseq:NP_013146.1|sgd:S000004035|ensemblfungi:YLR045C(gene)|ensemblfungi:YLR045C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005816"(spindle pole body)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0061863"(microtubule plus end polymerase)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR034085|rcsb pdb:2QK1|rcsb pdb:4FFB|rcsb pdb:4U3J|rcsb pdb:6BL7|rcsb pdb:7KDF|dip:DIP-2462N|mint:P46675 psi-mi:"MI:0469"(intact) crc64:7A49C3702E21C7BF crc64:7A49C3702E21C7BF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MZSvgMGh+d1BYxGm4AEptyNQRfk559292 rogid:MZSvgMGh+d1BYxGm4AEptyNQRfk559292 intact-crc:2B8294C5DFF7D9F0|rigid:XSBZ0rf1dPdY4R0OHE22s0Cp5is false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46682 uniprotkb:P46682 intact:EBI-2213|uniprotkb:D6VV40|ensemblfungi:YGR261C intact:EBI-2213|uniprotkb:D6VV40|ensemblfungi:YGR261C psi-mi:ap3b_yeast(display_long)|uniprotkb:APL6(gene name)|psi-mi:APL6(display_short)|uniprotkb:YKS5(gene name synonym)|uniprotkb:YGR261C(locus name)|uniprotkb:G9331(orf name)|uniprotkb:Beta-3-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 3 beta large chain(gene name synonym)|uniprotkb:Clathrin assembly protein large beta chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit beta(gene name synonym) psi-mi:ap3b_yeast(display_long)|uniprotkb:APL6(gene name)|psi-mi:APL6(display_short)|uniprotkb:YKS5(gene name synonym)|uniprotkb:YGR261C(locus name)|uniprotkb:G9331(orf name)|uniprotkb:Beta-3-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 3 beta large chain(gene name synonym)|uniprotkb:Clathrin assembly protein large beta chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit beta(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334125|imex:IM-14275-1836 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003493|refseq:NP_011777.3|ensemblfungi:YGR261C(gene)|ensemblfungi:YGR261C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030665"(clathrin-coated vesicle membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026739|interpro:IPR026740|dip:DIP-2684N|mint:P46682 sgd:S000003493|refseq:NP_011777.3|ensemblfungi:YGR261C(gene)|ensemblfungi:YGR261C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030665"(clathrin-coated vesicle membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026739|interpro:IPR026740|dip:DIP-2684N|mint:P46682 psi-mi:"MI:0469"(intact) crc64:475DA3A4F6E68E97 crc64:475DA3A4F6E68E97 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:J+pCwMtq9Jhj24BeTVg7XpCHmKE559292 rogid:J+pCwMtq9Jhj24BeTVg7XpCHmKE559292 intact-crc:39E14240ED5944F2|rigid:qpP8+7RlauqzOOv92Cb4cnieIMw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08951 uniprotkb:P46682 intact:EBI-29702|uniprotkb:Q02737|uniprotkb:Q7LIB1|uniprotkb:D6W3H3|ensemblfungi:YPL195W intact:EBI-2213|uniprotkb:D6VV40|ensemblfungi:YGR261C psi-mi:ap3d_yeast(display_long)|uniprotkb:YPL195W(locus name)|uniprotkb:Delta-adaptin 3(gene name synonym)|uniprotkb:APL5(gene name)|psi-mi:APL5(display_short)|uniprotkb:YKS4(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit delta(gene name synonym) psi-mi:ap3b_yeast(display_long)|uniprotkb:APL6(gene name)|psi-mi:APL6(display_short)|uniprotkb:YKS5(gene name synonym)|uniprotkb:YGR261C(locus name)|uniprotkb:G9331(orf name)|uniprotkb:Beta-3-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 3 beta large chain(gene name synonym)|uniprotkb:Clathrin assembly protein large beta chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit beta(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334136|imex:IM-14275-1837 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015129.1|sgd:S000006116|dip:DIP-3977N|mint:Q08951|ensemblfungi:YPL195W(gene)|ensemblfungi:YPL195W_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030665"(clathrin-coated vesicle membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017105(Adaptor protein complex AP-3, delta subunit) sgd:S000003493|refseq:NP_011777.3|ensemblfungi:YGR261C(gene)|ensemblfungi:YGR261C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030665"(clathrin-coated vesicle membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026739|interpro:IPR026740|dip:DIP-2684N|mint:P46682 psi-mi:"MI:0469"(intact) crc64:51415466FF25CC40 crc64:475DA3A4F6E68E97 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mCtBXyUDDBZ4freC+1z5iPIEJTo559292 rogid:J+pCwMtq9Jhj24BeTVg7XpCHmKE559292 intact-crc:A99CD67515C387D5|rigid:/CzZtYtBeODHWKZIunRgr6aedik false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46682 uniprotkb:Q12114 intact:EBI-2213|uniprotkb:D6VV40|ensemblfungi:YGR261C intact:EBI-4640|uniprotkb:D6VYX2|ensemblfungi:YLR330W psi-mi:ap3b_yeast(display_long)|uniprotkb:APL6(gene name)|psi-mi:APL6(display_short)|uniprotkb:YKS5(gene name synonym)|uniprotkb:YGR261C(locus name)|uniprotkb:G9331(orf name)|uniprotkb:Beta-3-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 3 beta large chain(gene name synonym)|uniprotkb:Clathrin assembly protein large beta chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit beta(gene name synonym) psi-mi:chs5_yeast(display_long)|uniprotkb:CHS5(gene name)|psi-mi:CHS5(display_short)|uniprotkb:CAL3(gene name synonym)|uniprotkb:YLR330W(locus name)|uniprotkb:L8543.18(orf name)|uniprotkb:Protein CAL3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334147|imex:IM-14275-1838 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003493|refseq:NP_011777.3|ensemblfungi:YGR261C(gene)|ensemblfungi:YGR261C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030665"(clathrin-coated vesicle membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026739|interpro:IPR026740|dip:DIP-2684N|mint:P46682 refseq:NP_013434.1|sgd:S000004322|dip:DIP-8073N|mint:Q12114|ensemblfungi:YLR330W(gene)|ensemblfungi:YLR330W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006039"(cell wall chitin catabolic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034044"(exomer complex)|go:"GO:0043332"(mating projection tip)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001357(BRCT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031669|interpro:IPR031673|interpro:IPR036116|interpro:IPR036420|rcsb pdb:4IN3|rcsb pdb:4WJW|rcsb pdb:4YG8 psi-mi:"MI:0469"(intact) crc64:475DA3A4F6E68E97 crc64:FA92741B862814C2 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:J+pCwMtq9Jhj24BeTVg7XpCHmKE559292 rogid:iHvfW3fNLv3HLj4Ihya1Vyt0X7I559292 intact-crc:245E7F3C83B6284B|rigid:PKRe3cs8RCoR0kXEHJ7lX65a4ms false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46956 uniprotkb:P10614 intact:EBI-13337|uniprotkb:E9P8T7|ensemblfungi:YJL117W|uniprotkb:D6VW67 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:pho86_yeast(display_long)|uniprotkb:PHO86(gene name)|psi-mi:PHO86(display_short)|uniprotkb:J0744(orf name)|uniprotkb:YJL117W(locus name) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334158|imex:IM-14275-1839 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012418.1|sgd:S000003653|interpro:IPR024297|ensemblfungi:YJL117W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0010966"(regulation of phosphate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051082"(unfolded protein binding)|ensemblfungi:YJL117W(gene)|mint:P46956|dip:DIP-2769N refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) crc64:1CB19C9184BF1C48 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:JITWReptfMoij1Uy6y1e3Oa6dAs559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:A1010476C8F8A7DA|rigid:I1MxUe0y8owYf2Mzj9A+jShScxI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40207 uniprotkb:P46956 intact:EBI-27272|uniprotkb:D6VZV7|ensemblfungi:YMR134W intact:EBI-13337|uniprotkb:E9P8T7|ensemblfungi:YJL117W|uniprotkb:D6VW67 psi-mi:erg29_yeast(display_long)|uniprotkb:ERG29(gene name)|psi-mi:ERG29(display_short)|uniprotkb:YM9375.03(orf name)|uniprotkb:YMR134W(locus name) psi-mi:pho86_yeast(display_long)|uniprotkb:PHO86(gene name)|psi-mi:PHO86(display_short)|uniprotkb:J0744(orf name)|uniprotkb:YJL117W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334169|imex:IM-14275-1840 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013853.1|sgd:S000004741|mint:P40207|dip:DIP-4433N|ensemblfungi:YMR134W(gene)|ensemblfungi:YMR134W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0016021"(integral component of membrane) refseq:NP_012418.1|sgd:S000003653|interpro:IPR024297|ensemblfungi:YJL117W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0010966"(regulation of phosphate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051082"(unfolded protein binding)|ensemblfungi:YJL117W(gene)|mint:P46956|dip:DIP-2769N psi-mi:"MI:0469"(intact) - crc64:1CB19C9184BF1C48 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6ByNiLUswj10x66D1WrAHOI9t7c559292 rogid:JITWReptfMoij1Uy6y1e3Oa6dAs559292 intact-crc:F7978529EEDD8374|rigid:z68VcowHRCZW5AodG0T68Y0DkiM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40540 uniprotkb:P46956 intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C intact:EBI-13337|uniprotkb:E9P8T7|ensemblfungi:YJL117W|uniprotkb:D6VW67 psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:pho86_yeast(display_long)|uniprotkb:PHO86(gene name)|psi-mi:PHO86(display_short)|uniprotkb:J0744(orf name)|uniprotkb:YJL117W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334180|imex:IM-14275-1841 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX refseq:NP_012418.1|sgd:S000003653|interpro:IPR024297|ensemblfungi:YJL117W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0010966"(regulation of phosphate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051082"(unfolded protein binding)|ensemblfungi:YJL117W(gene)|mint:P46956|dip:DIP-2769N psi-mi:"MI:0469"(intact) crc64:6DBEEEE7722203B0 crc64:1CB19C9184BF1C48 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 rogid:JITWReptfMoij1Uy6y1e3Oa6dAs559292 intact-crc:459FA236CE5B9EB7|rigid:zoNO1Q+MDCb8K85HwaUNwKg7R1E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46963 uniprotkb:P46962 intact:EBI-5241|uniprotkb:Q6LBS6|uniprotkb:D6W0H2|ensemblfungi:YML112W intact:EBI-5236|uniprotkb:D6VWG9|ensemblfungi:YJL006C psi-mi:ctk3_yeast(display_long)|uniprotkb:CTK3(gene name)|psi-mi:CTK3(display_short)|uniprotkb:YML112W(locus name)|uniprotkb:YM8339.07(orf name)|uniprotkb:CTD kinase subunit 3(gene name synonym)|uniprotkb:CTD kinase 32 kDa subunit(gene name synonym) psi-mi:ctk2_yeast(display_long)|uniprotkb:CTK2(gene name)|psi-mi:CTK2(display_short)|uniprotkb:YJL006C(locus name)|uniprotkb:J1390(orf name)|uniprotkb:CTD kinase subunit 2(gene name synonym)|uniprotkb:CTD kinase 38 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334191|imex:IM-14275-1842 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013595.1|sgd:S000004580|dip:DIP-2106N|mint:P46963|ensemblfungi:YML112W(gene)|ensemblfungi:YML112W_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0071619"(phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|interpro:IPR024637|interpro:IPR042326|rcsb pdb:7JV7 refseq:NP_012528.1|sgd:S000003543|dip:DIP-2105N|mint:P46962|ensemblfungi:YJL006C(gene)|ensemblfungi:YJL006C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070692"(CTDK-1 complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR043198|rcsb pdb:7JV7|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-75955|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) crc64:12F6D3F7181547ED - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4/8OqeRrS+55eRrdLGZ6z8M0EOA559292 rogid:NXQinB6zZUQR/mKhTNMq+5j6dP0559292 intact-crc:CB21130A65AE6343|rigid:kpWRAklKZOfENzSIwRgyBMsxbuU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46965 uniprotkb:P10614 intact:EBI-17823|uniprotkb:D6VWI6|ensemblfungi:YJR010C-A intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:spc1_yeast(display_long)|uniprotkb:SPC1(gene name)|psi-mi:SPC1(display_short)|uniprotkb:YJR010C-A(locus name)|uniprotkb:YJR010BW(orf name)|uniprotkb:Microsomal signal peptidase subunit 1(gene name synonym) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334202|imex:IM-14275-1843 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012544.1|sgd:S000003770|ensemblfungi:YJR010C-A(gene)|ensemblfungi:YJR010C-A_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009542(Microsomal signal peptidase 12 kDa subunit)|interpro:IPR037713|mint:P46965|dip:DIP-2770N refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kchUi3mkadvzweVkrWO3QkbbHew559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:222AD201CC8A59C5|rigid:qw7m8SKzHz3/ToXR21xXt7WmT1s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21825 uniprotkb:P46965 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 intact:EBI-17823|uniprotkb:D6VWI6|ensemblfungi:YJR010C-A psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:spc1_yeast(display_long)|uniprotkb:SPC1(gene name)|psi-mi:SPC1(display_short)|uniprotkb:YJR010C-A(locus name)|uniprotkb:YJR010BW(orf name)|uniprotkb:Microsomal signal peptidase subunit 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334213|imex:IM-14275-1844 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 refseq:NP_012544.1|sgd:S000003770|ensemblfungi:YJR010C-A(gene)|ensemblfungi:YJR010C-A_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009542(Microsomal signal peptidase 12 kDa subunit)|interpro:IPR037713|mint:P46965|dip:DIP-2770N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 rogid:kchUi3mkadvzweVkrWO3QkbbHew559292 intact-crc:AEA97055DF0A2B46|rigid:penyiplb5wyFMld4bvTfeXYgeOw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:P46965 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-17823|uniprotkb:D6VWI6|ensemblfungi:YJR010C-A psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:spc1_yeast(display_long)|uniprotkb:SPC1(gene name)|psi-mi:SPC1(display_short)|uniprotkb:YJR010C-A(locus name)|uniprotkb:YJR010BW(orf name)|uniprotkb:Microsomal signal peptidase subunit 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334224|imex:IM-14275-1845 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N refseq:NP_012544.1|sgd:S000003770|ensemblfungi:YJR010C-A(gene)|ensemblfungi:YJR010C-A_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009542(Microsomal signal peptidase 12 kDa subunit)|interpro:IPR037713|mint:P46965|dip:DIP-2770N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:kchUi3mkadvzweVkrWO3QkbbHew559292 intact-crc:353CD0D711AAE508|rigid:JibVATkEhhlMoS+nFHyv31Xh12U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46965 uniprotkb:P39727 intact:EBI-17823|uniprotkb:D6VWI6|ensemblfungi:YJR010C-A intact:EBI-20659|uniprotkb:D6VPH4|ensemblfungi:YAL042W psi-mi:spc1_yeast(display_long)|uniprotkb:SPC1(gene name)|psi-mi:SPC1(display_short)|uniprotkb:YJR010C-A(locus name)|uniprotkb:YJR010BW(orf name)|uniprotkb:Microsomal signal peptidase subunit 1(gene name synonym) psi-mi:erv46_yeast(display_long)|uniprotkb:FUN9(orf name)|uniprotkb:YAL042W(locus name)|uniprotkb:ERV46(gene name)|psi-mi:ERV46(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334235|imex:IM-14275-1846 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012544.1|sgd:S000003770|ensemblfungi:YJR010C-A(gene)|ensemblfungi:YJR010C-A_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009542(Microsomal signal peptidase 12 kDa subunit)|interpro:IPR037713|mint:P46965|dip:DIP-2770N refseq:NP_009358.1|sgd:S000000040|ensemblfungi:YAL042W(gene)|ensemblfungi:YAL042W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|dip:DIP-3792N|mint:P39727 psi-mi:"MI:0469"(intact) - crc64:FB7BC171B88BB5EA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kchUi3mkadvzweVkrWO3QkbbHew559292 rogid:tVyaLk7odK7bfnaz1FMv0E9lgtU559292 intact-crc:E314DABBC4C3E78D|rigid:q1eiB8oyTcnfAZKZbxmRHUJBzFg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04651 uniprotkb:P46965 intact:EBI-27850|uniprotkb:E9PAD9|uniprotkb:D6VZA6|ensemblfungi:YML067C intact:EBI-17823|uniprotkb:D6VWI6|ensemblfungi:YJR010C-A psi-mi:erv41_yeast(display_long)|uniprotkb:YML067C(locus name)|uniprotkb:ERV41(gene name)|psi-mi:ERV41(display_short) psi-mi:spc1_yeast(display_long)|uniprotkb:SPC1(gene name)|psi-mi:SPC1(display_short)|uniprotkb:YJR010C-A(locus name)|uniprotkb:YJR010BW(orf name)|uniprotkb:Microsomal signal peptidase subunit 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334246|imex:IM-14275-1847 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013644.1|sgd:S000004532|dip:DIP-6791N|mint:Q04651|ensemblfungi:YML067C(gene)|ensemblfungi:YML067C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|rcsb pdb:3ZLC refseq:NP_012544.1|sgd:S000003770|ensemblfungi:YJR010C-A(gene)|ensemblfungi:YJR010C-A_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009542(Microsomal signal peptidase 12 kDa subunit)|interpro:IPR037713|mint:P46965|dip:DIP-2770N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IpGpvBxckHz1ExXTnTsKEHU2su8559292 rogid:kchUi3mkadvzweVkrWO3QkbbHew559292 intact-crc:7C1E550E5D4731FF|rigid:ngWwqJTgDMzjQdtF2zX91bpWw3o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:P46965 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-17823|uniprotkb:D6VWI6|ensemblfungi:YJR010C-A psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:spc1_yeast(display_long)|uniprotkb:SPC1(gene name)|psi-mi:SPC1(display_short)|uniprotkb:YJR010C-A(locus name)|uniprotkb:YJR010BW(orf name)|uniprotkb:Microsomal signal peptidase subunit 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334257|imex:IM-14275-1848 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_012544.1|sgd:S000003770|ensemblfungi:YJR010C-A(gene)|ensemblfungi:YJR010C-A_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009542(Microsomal signal peptidase 12 kDa subunit)|interpro:IPR037713|mint:P46965|dip:DIP-2770N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:kchUi3mkadvzweVkrWO3QkbbHew559292 intact-crc:3C7D7C3DEC505758|rigid:Q+iWWMzWG9xDa5ulhvVHb8kuokk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06144 uniprotkb:P46965 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W intact:EBI-17823|uniprotkb:D6VWI6|ensemblfungi:YJR010C-A psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:spc1_yeast(display_long)|uniprotkb:SPC1(gene name)|psi-mi:SPC1(display_short)|uniprotkb:YJR010C-A(locus name)|uniprotkb:YJR010BW(orf name)|uniprotkb:Microsomal signal peptidase subunit 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334268|imex:IM-14275-1849 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 refseq:NP_012544.1|sgd:S000003770|ensemblfungi:YJR010C-A(gene)|ensemblfungi:YJR010C-A_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009542(Microsomal signal peptidase 12 kDa subunit)|interpro:IPR037713|mint:P46965|dip:DIP-2770N psi-mi:"MI:0469"(intact) crc64:2F474503CAB7C195 - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 rogid:kchUi3mkadvzweVkrWO3QkbbHew559292 intact-crc:7FD9744B8AA35720|rigid:WWRJtXqt9MyMT9kQX6paLVjMURY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46989 uniprotkb:P11076 intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334279|imex:IM-14275-1850 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 psi-mi:"MI:0469"(intact) - crc64:796859026AC63CC0 figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 intact-crc:F6E797D3F84DE77B|rigid:CyCzbqzwBUQPwPEZ/IrxasfP3cs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32319 uniprotkb:P46989 intact:EBI-13123|uniprotkb:D6VPY3|ensemblfungi:YBL017C intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C psi-mi:vps10_yeast(display_long)|uniprotkb:PEP1(gene name)|psi-mi:PEP1(display_short)|uniprotkb:Vacuolar carboxypeptidase sorting receptor VPS10(gene name synonym)|uniprotkb:Carboxypeptidase Y receptor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 1(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 1(gene name synonym)|uniprotkb:Sortilin VPS10(gene name synonym)|uniprotkb:VPS10(gene name synonym)|uniprotkb:VPT1(gene name synonym)|uniprotkb:YBL03.22(orf name)|uniprotkb:YBL0302(orf name)|uniprotkb:YBL017C(locus name) psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334290|imex:IM-14275-1851 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009536.1|sgd:S000000113|mint:P32319|dip:DIP-5900N|ensemblfungi:YBL017C(gene)|ensemblfungi:YBL017C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000423"(mitophagy)|go:"GO:0000425"(pexophagy)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048203"(vesicle targeting, trans-Golgi to endosome)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR036278 refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:C778A0400612ECF4 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dYYsekAaDw4SzmEUSe5tYb5a43M559292 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 intact-crc:50EE3FE4F04F33B0|rigid:jkYlz7hzhTbrr7Pleyt1uO804wY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32798 uniprotkb:P46989 intact:EBI-5006|uniprotkb:D6W314|ensemblfungi:YOR316C intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C psi-mi:cot1_yeast(display_long)|uniprotkb:COT1(gene name)|psi-mi:COT1(display_short)|uniprotkb:O6131(orf name)|uniprotkb:YOR316C(locus name) psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334301|imex:IM-14275-1852 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005843|refseq:NP_014961.3|dip:DIP-7554N|mint:P32798|ensemblfungi:YOR316C(gene)|ensemblfungi:YOR316C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006824"(cobalt ion transport)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0015087"(cobalt ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410 refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HEIg6lhS698E9H3BJeESYAipNwA559292 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 intact-crc:115A093068CF92D6|rigid:PI9hOl5EvJymtuXzL2TEzhJIBTs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46989 uniprotkb:P32913 intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C intact:EBI-20366|uniprotkb:Q12279|uniprotkb:D6W2J0|ensemblfungi:YOR132W psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:vps17_yeast(display_long)|uniprotkb:VPS17(gene name)|psi-mi:VPS17(display_short)|uniprotkb:PEP21(gene name synonym)|uniprotkb:YOR132W(locus name)|uniprotkb:O3314(orf name)|uniprotkb:YOR3314W(orf name)|uniprotkb:Carboxypeptidase Y-deficient protein 21(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334312|imex:IM-14275-1853 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 sgd:S000005658|refseq:NP_014775.3|ensemblfungi:YOR132W(gene)|ensemblfungi:YOR132W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR001683(Phox-like)|interpro:IPR014461(Vacuolar protein sorting-associated protein Vps17)|interpro:IPR027267|interpro:IPR036871|interpro:IPR037907|dip:DIP-1739N|mint:P32913 psi-mi:"MI:0469"(intact) - crc64:C709968468144A50 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 rogid:X5nNIyX3T0PYprdyJaxVnc8RoR8559292 intact-crc:C04BF5C8615C501B|rigid:thRv1AEUdlZ2the3e/vA9SYVg8M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46989 uniprotkb:P38310 intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334323|imex:IM-14275-1854 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) - crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:7DE49A0FA6FA4573|rigid:tt7tzjzJe6q2wzbz1cgrczU/cCA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46989 uniprotkb:P38929 intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334334|imex:IM-14275-1855 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 psi-mi:"MI:0469"(intact) - crc64:5BD9ECFF8508F396 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 intact-crc:5FE2502EFDA404B6|rigid:0GX3aYsV7CDWyb3U6tioHZiiyjw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46989 uniprotkb:P46989 intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334345|imex:IM-14275-1856 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 intact-crc:96294AD4E85831B1|rigid:iRVYu6cPxs05wDPNfqTsEvnR+y4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03308 uniprotkb:P46989 intact:EBI-20355|uniprotkb:Q03078|uniprotkb:D6W3W9|ensemblfungi:YPL045W intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C psi-mi:vps16_yeast(display_long)|uniprotkb:VPS16(gene name)|psi-mi:VPS16(display_short)|uniprotkb:VAM9(gene name synonym)|uniprotkb:VPT16(gene name synonym)|uniprotkb:YPL045W(locus name)|uniprotkb:Vacuolar morphogenesis protein 9(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 16(gene name synonym) psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334356|imex:IM-14275-1857 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015280.1|sgd:S000005966|ensemblfungi:YPL045W(gene)|ensemblfungi:YPL045W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003779"(actin binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0007033"(vacuole organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0099022"(vesicle tethering)|interpro:IPR006925(Vps16, C-terminal)|interpro:IPR006926(Vps16, N-terminal)|interpro:IPR016534(Vacuolar protein sorting-associated protein 16)|interpro:IPR038132|dip:DIP-6691N|mint:Q03308 refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VEp4KoyGgrM+WSMK2PZN9NqqP0g559292 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 intact-crc:4228CDCAC162827C|rigid:Dn5kcZkDqyb51kCKuCpEhFp+bQQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03730 uniprotkb:P46989 intact:EBI-27739|uniprotkb:Q6B2K7|uniprotkb:D6VZF6|ensemblfungi:YML018C intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C psi-mi:ymb8_yeast(display_long)|uniprotkb:YML018C(locus name) psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334367|imex:IM-14275-1858 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004480|refseq:NP_013694.1|dip:DIP-4953N|mint:Q03730|ensemblfungi:YML018C(gene)|ensemblfungi:YML018C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane) refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:DEC5C3EEF293F5ED - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4WxEFdhqbP7pcRcTLeFHljCVQ34559292 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 intact-crc:71452102A836FBE8|rigid:HVUnwldZYM+1PQjgRme+kva4ZIo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46989 uniprotkb:Q03860 intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334378|imex:IM-14275-1859 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) - crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:23581FC27E4708A0|rigid:9rH2bACKabJVQs5yCcADVbm7TmA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46989 uniprotkb:Q08826 intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C intact:EBI-17603|ensemblfungi:YOR357C|uniprotkb:D6W352 psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:snx3_yeast(display_long)|uniprotkb:SNX3(gene name)|psi-mi:SNX3(display_short)|uniprotkb:GRD19(gene name synonym)|uniprotkb:YOR357C(locus name)|uniprotkb:Golgi retention deficient protein 19(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334389|imex:IM-14275-1860 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 go:"GO:0030904"(retromer complex)|ensemblfungi:YOR357C(gene)|ensemblfungi:YOR357C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032994"(protein-lipid complex)|go:"GO:0034499"(late endosome to Golgi transport)|rcsb pdb:1OCS|rcsb pdb:1OCU|reactome:R-SCE-3238698|reactome:R-SCE-5689880|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|interpro:IPR001683(Phox-like)|sgd:S000005884|interpro:IPR042138|refseq:NP_015002.3|mint:Q08826|interpro:IPR036871 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 rogid:d/G9NZa1VdfC1zs03H49a1KMNRg559292 intact-crc:8A8BBAF739AD4762|rigid:JyB2OCPHZGQNa//lBWZFZXm7R6A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46989 uniprotkb:Q12016 intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C intact:EBI-29309|uniprotkb:D6W1T9|ensemblfungi:YOL129W psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:vps68_yeast(display_long)|uniprotkb:YOL129W(locus name)|uniprotkb:VPS68(gene name)|psi-mi:VPS68(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334400|imex:IM-14275-1861 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 refseq:NP_014512.1|sgd:S000005489|dip:DIP-1732N|mint:Q12016|ensemblfungi:YOL129W(gene)|ensemblfungi:YOL129W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0034424"(Vps55/Vps68 complex)|interpro:IPR007919(Protein of unknown function UPF0220) psi-mi:"MI:0469"(intact) - crc64:4B21C846AB3BA2A7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 rogid:I6sUyfNcLBsFG3OtDUfEqohxLB4559292 intact-crc:D08A19E1EF040260|rigid:tQONisiRUlIDZmmE3bdFfiCwqMg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12116 uniprotkb:P46989 intact:EBI-19306|uniprotkb:D6VS91|ensemblfungi:YDR105C intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C psi-mi:tms1_yeast(display_long)|uniprotkb:YDR105C(locus name)|uniprotkb:TMS1(gene name)|psi-mi:TMS1(display_short) psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334411|imex:IM-14275-1862 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002512|ensemblfungi:YDR105C(gene)|ensemblfungi:YDR105C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR005016(TMS membrane protein/tumour differentially expressed protein)|interpro:IPR029559|reactome:R-SCE-977347|refseq:NP_010390.3|dip:DIP-5198N|mint:Q12116 refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:DFA9011F9D56EEDE - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2r+KaCny/GXJUQ87u+f97/LLn+k559292 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 intact-crc:AFDB4658E4222794|rigid:MaekirT/18+deEC+YWxOnLLU6SU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:P46989 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334422|imex:IM-14275-1863 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 intact-crc:987F08ADF1ADB5B7|rigid:Xr4eXBQJEM0oZQiWm5E4Gnm0Iqk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q2V2P9 uniprotkb:P46989 intact:EBI-6329877|ensemblfungi:YDR119W-A|uniprotkb:D6VSA5 intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C psi-mi:cox26_yeast(display_long)|uniprotkb:COX26(gene name)|psi-mi:COX26(display_short)|uniprotkb:YDR119W-A(locus name) psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334433|imex:IM-14275-1864 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR119W-A(gene)|ensemblfungi:YDR119W-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:6HU9|rcsb pdb:6T0B|rcsb pdb:6T15|rcsb pdb:6YMX|rcsb pdb:6YMY|mint:Q2V2P9|refseq:NP_001032575.1|sgd:S000113555 refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:y+ngl2QASMkgvhfqYQcKuy/Cd9A559292 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 intact-crc:C8653181CE71CFCA|rigid:DDSRD2DOlRrdrbKoq4MCFFId0/w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92331 uniprotkb:P46989 intact:EBI-20483|uniprotkb:Q08483|uniprotkb:D6W2D1|uniprotkb:E9P8U6|ensemblfungi:YOR069W intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C psi-mi:vps5_yeast(display_long)|uniprotkb:VPS5(gene name)|psi-mi:VPS5(display_short)|uniprotkb:GRD2(gene name synonym)|uniprotkb:PEP10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 5(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 10(gene name synonym)|uniprotkb:VPT5(gene name synonym)|uniprotkb:YOR29-20(orf name)|uniprotkb:YOR069W(locus name) psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334444|imex:IM-14275-1865 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014712.2|sgd:S000005595|ensemblfungi:YOR069W(gene)|ensemblfungi:YOR069W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0005768"(endosome)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|interpro:IPR001683(Phox-like)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028648|interpro:IPR035803|interpro:IPR036871|interpro:IPR037868|dip:DIP-1740N|mint:Q92331 refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5aPSkQUJV1sfIc9Ql+wMP74Y3QI559292 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 intact-crc:32944044BA20465F|rigid:wLtbeFAaUBDK8vw4Wm0WcOVueMw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47006 uniprotkb:P32495 intact:EBI-26109|uniprotkb:D6VW37|ensemblfungi:YJL148W intact:EBI-12014|ensemblfungi:YDL208W|uniprotkb:D6VRE6 psi-mi:rpa34_yeast(display_long)|uniprotkb:YJL148W(locus name)|uniprotkb:J0637(orf name)|uniprotkb:RPA34(gene name)|psi-mi:RPA34(display_short)|uniprotkb:DNA-directed DNA-dependent RNA polymerase 34.5 kDa polypeptide(gene name synonym) psi-mi:nhp2_yeast(display_long)|uniprotkb:NHP2(gene name)|psi-mi:NHP2(display_short)|uniprotkb:YDL208W(locus name)|uniprotkb:D1045(orf name)|uniprotkb:H/ACA snoRNP protein NHP2(gene name synonym)|uniprotkb:High mobility group-like nuclear protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334455|imex:IM-14275-1866 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012387.1|sgd:S000003684|mint:P47006|dip:DIP-7973N|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|ensemblfungi:YJL148W(gene)|ensemblfungi:YJL148W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR013240(RNA polymerase I, subunit RPA34.5, fungi)|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61 ensemblfungi:YDL208W(gene)|ensemblfungi:YDL208W_mRNA(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000493"(box H/ACA snoRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|rcsb pdb:2LBW|rcsb pdb:2LBX|refseq:NP_010073.2|sgd:S000002367|mint:P32495|dip:DIP-5134N psi-mi:"MI:0469"(intact) crc64:DCD42DFEC574EDB6 crc64:008188132B494E5D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:KCG3Ws8+82TSLsqPB7bedHq/JEI559292 rogid:p5AQTuMF3Vvdu6HWSTYjdjjE1Vs559292 intact-crc:3C144B67C7CD898E|rigid:4EPf3ZeWFz8WKUyMQH4oMmbifS4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47006 uniprotkb:P47006 intact:EBI-26109|uniprotkb:D6VW37|ensemblfungi:YJL148W intact:EBI-26109|uniprotkb:D6VW37|ensemblfungi:YJL148W psi-mi:rpa34_yeast(display_long)|uniprotkb:YJL148W(locus name)|uniprotkb:J0637(orf name)|uniprotkb:RPA34(gene name)|psi-mi:RPA34(display_short)|uniprotkb:DNA-directed DNA-dependent RNA polymerase 34.5 kDa polypeptide(gene name synonym) psi-mi:rpa34_yeast(display_long)|uniprotkb:YJL148W(locus name)|uniprotkb:J0637(orf name)|uniprotkb:RPA34(gene name)|psi-mi:RPA34(display_short)|uniprotkb:DNA-directed DNA-dependent RNA polymerase 34.5 kDa polypeptide(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334466|imex:IM-14275-1867 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012387.1|sgd:S000003684|mint:P47006|dip:DIP-7973N|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|ensemblfungi:YJL148W(gene)|ensemblfungi:YJL148W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR013240(RNA polymerase I, subunit RPA34.5, fungi)|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61 refseq:NP_012387.1|sgd:S000003684|mint:P47006|dip:DIP-7973N|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|ensemblfungi:YJL148W(gene)|ensemblfungi:YJL148W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR013240(RNA polymerase I, subunit RPA34.5, fungi)|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61 psi-mi:"MI:0469"(intact) crc64:DCD42DFEC574EDB6 crc64:DCD42DFEC574EDB6 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:KCG3Ws8+82TSLsqPB7bedHq/JEI559292 rogid:KCG3Ws8+82TSLsqPB7bedHq/JEI559292 intact-crc:75359F3B186E432D|rigid:ITM4mcsv2A3GTNRamxTUEe7dZ98 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47006 uniprotkb:P53131 intact:EBI-26109|uniprotkb:D6VW37|ensemblfungi:YJL148W intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 psi-mi:rpa34_yeast(display_long)|uniprotkb:YJL148W(locus name)|uniprotkb:J0637(orf name)|uniprotkb:RPA34(gene name)|psi-mi:RPA34(display_short)|uniprotkb:DNA-directed DNA-dependent RNA polymerase 34.5 kDa polypeptide(gene name synonym) psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334477|imex:IM-14275-1868 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012387.1|sgd:S000003684|mint:P47006|dip:DIP-7973N|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|ensemblfungi:YJL148W(gene)|ensemblfungi:YJL148W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR013240(RNA polymerase I, subunit RPA34.5, fungi)|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61 go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131 psi-mi:"MI:0469"(intact) crc64:DCD42DFEC574EDB6 crc64:DA8A085EC50FF430 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:KCG3Ws8+82TSLsqPB7bedHq/JEI559292 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 intact-crc:B8B872923B7E7224|rigid:rN2HDRc9Ca5S+srwqEtoAbcli/w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47006 uniprotkb:Q03525 intact:EBI-26109|uniprotkb:D6VW37|ensemblfungi:YJL148W intact:EBI-27597|uniprotkb:Q7Z870|ensemblfungi:YMR269W|uniprotkb:D6W095 psi-mi:rpa34_yeast(display_long)|uniprotkb:YJL148W(locus name)|uniprotkb:J0637(orf name)|uniprotkb:RPA34(gene name)|psi-mi:RPA34(display_short)|uniprotkb:DNA-directed DNA-dependent RNA polymerase 34.5 kDa polypeptide(gene name synonym) psi-mi:tma23_yeast(display_long)|uniprotkb:YMR269W(locus name)|uniprotkb:YM8156.11(orf name)|uniprotkb:TMA23(gene name)|psi-mi:TMA23(display_short)|uniprotkb:YMR268W-A(orf name)|uniprotkb:23 kDa translation machinery-associated protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334488|imex:IM-14275-1869 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012387.1|sgd:S000003684|mint:P47006|dip:DIP-7973N|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|ensemblfungi:YJL148W(gene)|ensemblfungi:YJL148W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR013240(RNA polymerase I, subunit RPA34.5, fungi)|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61 ensemblfungi:YMR269W(gene)|ensemblfungi:YMR269W_mRNA(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0042274"(ribosomal small subunit biogenesis)|sgd:S000004882|refseq:NP_013996.2|dip:DIP-1965N|mint:Q03525 psi-mi:"MI:0469"(intact) crc64:DCD42DFEC574EDB6 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:KCG3Ws8+82TSLsqPB7bedHq/JEI559292 rogid:yJy9JnQUnYKqa7aOQ5yEeHcNEpI559292 intact-crc:EF87869ED610F64D|rigid:qh7vmNg4bx6S6encNR9hMU2lt10 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6Q547 uniprotkb:P47006 intact:EBI-2052475|uniprotkb:D3DL22|ensemblfungi:YHR072W-A intact:EBI-26109|uniprotkb:D6VW37|ensemblfungi:YJL148W psi-mi:nop10_yeast(display_long)|uniprotkb:YHR072W-A(locus name)|uniprotkb:Nucleolar protein family A member 3(gene name synonym)|uniprotkb:snoRNP protein NOP10(gene name synonym)|uniprotkb:NOP10(gene name)|psi-mi:NOP10(display_short)|uniprotkb:Nucleolar protein 10(gene name synonym) psi-mi:rpa34_yeast(display_long)|uniprotkb:YJL148W(locus name)|uniprotkb:J0637(orf name)|uniprotkb:RPA34(gene name)|psi-mi:RPA34(display_short)|uniprotkb:DNA-directed DNA-dependent RNA polymerase 34.5 kDa polypeptide(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334499|imex:IM-14275-1870 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058135.1|sgd:S000007455|dip:DIP-5845N|mint:Q6Q547|ensemblfungi:YHR072W-A(gene)|ensemblfungi:YHR072W-A_mRNA(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|interpro:IPR007264(Nucleolar RNA-binding protein Nop10p)|interpro:IPR036756|rcsb pdb:1Y2Y|rcsb pdb:2AQA|rcsb pdb:3U28|rcsb pdb:3UAI refseq:NP_012387.1|sgd:S000003684|mint:P47006|dip:DIP-7973N|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|ensemblfungi:YJL148W(gene)|ensemblfungi:YJL148W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR013240(RNA polymerase I, subunit RPA34.5, fungi)|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61 psi-mi:"MI:0469"(intact) crc64:4718D35AF7911FBA crc64:DCD42DFEC574EDB6 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9m0x3DatObFwua2cbCQYMRKGqrU559292 rogid:KCG3Ws8+82TSLsqPB7bedHq/JEI559292 intact-crc:C3FF705EB86D8CC3|rigid:vJfjDNbFgZqcE+ayBtHkj5E2zHs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54783 uniprotkb:P47031 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 intact:EBI-25966|uniprotkb:D6VWA1|ensemblfungi:YJL082W psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:iml2_yeast(display_long)|uniprotkb:YJL082W(locus name)|uniprotkb:J1007(orf name)|uniprotkb:Increased minichromosome loss protein 2(gene name synonym)|uniprotkb:IML2(gene name)|psi-mi:IML2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334510|imex:IM-14275-1871 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 refseq:NP_012453.1|sgd:S000003618|mint:P47031|dip:DIP-4836N|ensemblfungi:YJL082W(gene)|ensemblfungi:YJL082W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR019412 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 rogid:m/5bx9Os1exjgSh/ARBYfJiwPWo559292 intact-crc:F5AEA25D01991D3B|rigid:mKZpMZvjzB5GenYkfwGwbN5vyqU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:P47068 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-3437|uniprotkb:P47067|uniprotkb:Q8X1F4|uniprotkb:D6VWG0|ensemblfungi:YJL020C psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:bbc1_yeast(display_long)|uniprotkb:Protein BBC1(gene name synonym)|uniprotkb:BBC1(gene name)|psi-mi:BBC1(display_short)|uniprotkb:MTI1(gene name synonym)|uniprotkb:J1286(orf name)|uniprotkb:J1305(orf name)|uniprotkb:YJL021C(orf name)|uniprotkb:YJL020C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334521|imex:IM-14275-1872 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N refseq:NP_012514.2|sgd:S000003557|dip:DIP-6279N|mint:P47068|ensemblfungi:YJL020C(gene)|ensemblfungi:YJL020C_mRNA(transcript)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0017024"(myosin I binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR030506|interpro:IPR035552|interpro:IPR036028|rcsb pdb:1TG0|rcsb pdb:1WDX|rcsb pdb:1ZUK|rcsb pdb:2DYF psi-mi:"MI:0469"(intact) - crc64:88A5899B89CCE8ED figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:2W/H/xmSbHD8h7GhTEytrAXVwr0559292 intact-crc:13668735B24716EB|rigid:ltg3pa4MtsdKW1ggqtmL5sxq9tI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38328 uniprotkb:P47068 intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C intact:EBI-3437|uniprotkb:P47067|uniprotkb:Q8X1F4|uniprotkb:D6VWG0|ensemblfungi:YJL020C psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:bbc1_yeast(display_long)|uniprotkb:Protein BBC1(gene name synonym)|uniprotkb:BBC1(gene name)|psi-mi:BBC1(display_short)|uniprotkb:MTI1(gene name synonym)|uniprotkb:J1286(orf name)|uniprotkb:J1305(orf name)|uniprotkb:YJL021C(orf name)|uniprotkb:YJL020C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334532|imex:IM-14275-1873 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 refseq:NP_012514.2|sgd:S000003557|dip:DIP-6279N|mint:P47068|ensemblfungi:YJL020C(gene)|ensemblfungi:YJL020C_mRNA(transcript)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0017024"(myosin I binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR030506|interpro:IPR035552|interpro:IPR036028|rcsb pdb:1TG0|rcsb pdb:1WDX|rcsb pdb:1ZUK|rcsb pdb:2DYF psi-mi:"MI:0469"(intact) crc64:D75C6BB8EC35EEDF crc64:88A5899B89CCE8ED figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 rogid:2W/H/xmSbHD8h7GhTEytrAXVwr0559292 intact-crc:5CA78E916BEAE4DB|rigid:GPCU8tSMCsLCJLG9TSw4ZtwQrK8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47068 uniprotkb:P40518 intact:EBI-3437|uniprotkb:P47067|uniprotkb:Q8X1F4|uniprotkb:D6VWG0|ensemblfungi:YJL020C intact:EBI-2750|uniprotkb:D6VVM2|ensemblfungi:YIL062C psi-mi:bbc1_yeast(display_long)|uniprotkb:Protein BBC1(gene name synonym)|uniprotkb:BBC1(gene name)|psi-mi:BBC1(display_short)|uniprotkb:MTI1(gene name synonym)|uniprotkb:J1286(orf name)|uniprotkb:J1305(orf name)|uniprotkb:YJL021C(orf name)|uniprotkb:YJL020C(locus name) psi-mi:arpc5_yeast(display_long)|uniprotkb:ARC15(gene name)|psi-mi:ARC15(display_short)|uniprotkb:Arp2/3 complex 16 kDa subunit(gene name synonym)|uniprotkb:YIL062C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334543|imex:IM-14275-1874 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012514.2|sgd:S000003557|dip:DIP-6279N|mint:P47068|ensemblfungi:YJL020C(gene)|ensemblfungi:YJL020C_mRNA(transcript)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0017024"(myosin I binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR030506|interpro:IPR035552|interpro:IPR036028|rcsb pdb:1TG0|rcsb pdb:1WDX|rcsb pdb:1ZUK|rcsb pdb:2DYF refseq:NP_012202.1|sgd:S000001324|dip:DIP-2101N|mint:P40518|ensemblfungi:YIL062C(gene)|ensemblfungi:YIL062C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR036743|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-6798695|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:88A5899B89CCE8ED crc64:10E4DAF0F0801B02 figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2W/H/xmSbHD8h7GhTEytrAXVwr0559292 rogid:iQ0mLisINMjXPulrRyDmrLcdpzU559292 intact-crc:0AA22DD54086C492|rigid:GSQGuxMccszRkq6LzrnNpquSx/Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47068 uniprotkb:P40563 intact:EBI-3437|uniprotkb:P47067|uniprotkb:Q8X1F4|uniprotkb:D6VWG0|ensemblfungi:YJL020C intact:EBI-25376|uniprotkb:D6VVT3|ensemblfungi:YIR003W psi-mi:bbc1_yeast(display_long)|uniprotkb:Protein BBC1(gene name synonym)|uniprotkb:BBC1(gene name)|psi-mi:BBC1(display_short)|uniprotkb:MTI1(gene name synonym)|uniprotkb:J1286(orf name)|uniprotkb:J1305(orf name)|uniprotkb:YJL021C(orf name)|uniprotkb:YJL020C(locus name) psi-mi:aim21_yeast(display_long)|uniprotkb:YIB3W(orf name)|uniprotkb:YIR003W(locus name)|uniprotkb:AIM21(gene name)|psi-mi:AIM21(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334554|imex:IM-14275-1875 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012514.2|sgd:S000003557|dip:DIP-6279N|mint:P47068|ensemblfungi:YJL020C(gene)|ensemblfungi:YJL020C_mRNA(transcript)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0017024"(myosin I binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR030506|interpro:IPR035552|interpro:IPR036028|rcsb pdb:1TG0|rcsb pdb:1WDX|rcsb pdb:1ZUK|rcsb pdb:2DYF sgd:S000001442|refseq:NP_012268.3|mint:P40563|dip:DIP-5096N|ensemblfungi:YIR003W(gene)|ensemblfungi:YIR003W_mRNA(transcript)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0034642"(mitochondrion migration along actin filament)|go:"GO:0043332"(mating projection tip)|go:"GO:0110131"(Aim21-Tda2 complex)|interpro:IPR021582 psi-mi:"MI:0469"(intact) crc64:88A5899B89CCE8ED crc64:9DF79500375339E7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2W/H/xmSbHD8h7GhTEytrAXVwr0559292 rogid:R3iO4ZZ2CQ4DGVK4ixn30Od6Tho559292 intact-crc:BD87F9ED7242C28D|rigid:1XkzLafsxf0z1ZLOlAbits1CtHU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47068 uniprotkb:P47068 intact:EBI-3437|uniprotkb:P47067|uniprotkb:Q8X1F4|uniprotkb:D6VWG0|ensemblfungi:YJL020C intact:EBI-3437|uniprotkb:P47067|uniprotkb:Q8X1F4|uniprotkb:D6VWG0|ensemblfungi:YJL020C psi-mi:bbc1_yeast(display_long)|uniprotkb:Protein BBC1(gene name synonym)|uniprotkb:BBC1(gene name)|psi-mi:BBC1(display_short)|uniprotkb:MTI1(gene name synonym)|uniprotkb:J1286(orf name)|uniprotkb:J1305(orf name)|uniprotkb:YJL021C(orf name)|uniprotkb:YJL020C(locus name) psi-mi:bbc1_yeast(display_long)|uniprotkb:Protein BBC1(gene name synonym)|uniprotkb:BBC1(gene name)|psi-mi:BBC1(display_short)|uniprotkb:MTI1(gene name synonym)|uniprotkb:J1286(orf name)|uniprotkb:J1305(orf name)|uniprotkb:YJL021C(orf name)|uniprotkb:YJL020C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334565|imex:IM-14275-1876 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012514.2|sgd:S000003557|dip:DIP-6279N|mint:P47068|ensemblfungi:YJL020C(gene)|ensemblfungi:YJL020C_mRNA(transcript)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0017024"(myosin I binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR030506|interpro:IPR035552|interpro:IPR036028|rcsb pdb:1TG0|rcsb pdb:1WDX|rcsb pdb:1ZUK|rcsb pdb:2DYF refseq:NP_012514.2|sgd:S000003557|dip:DIP-6279N|mint:P47068|ensemblfungi:YJL020C(gene)|ensemblfungi:YJL020C_mRNA(transcript)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0017024"(myosin I binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR030506|interpro:IPR035552|interpro:IPR036028|rcsb pdb:1TG0|rcsb pdb:1WDX|rcsb pdb:1ZUK|rcsb pdb:2DYF psi-mi:"MI:0469"(intact) crc64:88A5899B89CCE8ED crc64:88A5899B89CCE8ED figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2W/H/xmSbHD8h7GhTEytrAXVwr0559292 rogid:2W/H/xmSbHD8h7GhTEytrAXVwr0559292 intact-crc:F3EC6ADA407FCB78|rigid:nAEowqVs715hV9pA3GSXokn+aOQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04439 uniprotkb:P47068 intact:EBI-11687|ensemblfungi:YMR109W|uniprotkb:D6VZT2 intact:EBI-3437|uniprotkb:P47067|uniprotkb:Q8X1F4|uniprotkb:D6VWG0|ensemblfungi:YJL020C psi-mi:myo5_yeast(display_long)|uniprotkb:MYO5(gene name)|psi-mi:MYO5(display_short)|uniprotkb:YMR109W(locus name)|uniprotkb:YM9718.08(orf name)|uniprotkb:Class I unconventional myosin MYO5(gene name synonym)|uniprotkb:Type I myosin MYO5(gene name synonym)|uniprotkb:Actin-dependent myosin-I MYO5(gene name synonym) psi-mi:bbc1_yeast(display_long)|uniprotkb:Protein BBC1(gene name synonym)|uniprotkb:BBC1(gene name)|psi-mi:BBC1(display_short)|uniprotkb:MTI1(gene name synonym)|uniprotkb:J1286(orf name)|uniprotkb:J1305(orf name)|uniprotkb:YJL021C(orf name)|uniprotkb:YJL020C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334576|imex:IM-14275-1877 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR109W_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0009651"(response to salt stress)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051286"(cell tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071944"(cell periphery)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035535|ensemblfungi:YMR109W(gene)|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|rcsb pdb:1YP5|rcsb pdb:1ZUY|refseq:NP_013827.1|sgd:S000004715|mint:Q04439|dip:DIP-2222N refseq:NP_012514.2|sgd:S000003557|dip:DIP-6279N|mint:P47068|ensemblfungi:YJL020C(gene)|ensemblfungi:YJL020C_mRNA(transcript)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0017024"(myosin I binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR030506|interpro:IPR035552|interpro:IPR036028|rcsb pdb:1TG0|rcsb pdb:1WDX|rcsb pdb:1ZUK|rcsb pdb:2DYF psi-mi:"MI:0469"(intact) crc64:DFFB9EC16B61CD29 crc64:88A5899B89CCE8ED figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:n/Po/L9Xd7LP+fY39QaqP/s5US4559292 rogid:2W/H/xmSbHD8h7GhTEytrAXVwr0559292 intact-crc:C1DFA3251307D827|rigid:9O7+DCMfNRQXaKYBFyWlqYKP60E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25655 uniprotkb:P47093 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-313|uniprotkb:D6VWJ6|ensemblfungi:YJR022W psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:lsm8_yeast(display_long)|uniprotkb:LSM8(gene name)|psi-mi:LSM8(display_short)|uniprotkb:J1464(orf name)|uniprotkb:YJR83.16(orf name)|uniprotkb:YJR022W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334587|imex:IM-14275-1878 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 refseq:NP_012556.2|sgd:S000003783|ensemblfungi:YJR022W(gene)|ensemblfungi:YJR022W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034103|interpro:IPR044642|dip:DIP-903N|rcsb pdb:3JCM|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|mint:P47093 psi-mi:"MI:0469"(intact) crc64:5B2AE15BCF95E009 crc64:B6E37F585B6292EA figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:+X6fjvb8flf36BcPKxtclUwNMSY559292 intact-crc:03FBDF9334F5B743|rigid:MRGMJwMgEx+dbEvgEmsXVzCkOtw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06406 uniprotkb:P47093 intact:EBI-196|uniprotkb:D6VT10|ensemblfungi:YDR378C intact:EBI-313|uniprotkb:D6VWJ6|ensemblfungi:YJR022W psi-mi:lsm6_yeast(display_long)|uniprotkb:LSM6(gene name)|psi-mi:LSM6(display_short)|uniprotkb:D9481.18(orf name)|uniprotkb:YDR378C(locus name) psi-mi:lsm8_yeast(display_long)|uniprotkb:LSM8(gene name)|psi-mi:LSM8(display_short)|uniprotkb:J1464(orf name)|uniprotkb:YJR83.16(orf name)|uniprotkb:YJR022W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334598|imex:IM-14275-1879 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010666.2|sgd:S000002786|mint:Q06406|dip:DIP-1418N|ensemblfungi:YDR378C(gene)|ensemblfungi:YDR378C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0008033"(tRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 refseq:NP_012556.2|sgd:S000003783|ensemblfungi:YJR022W(gene)|ensemblfungi:YJR022W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034103|interpro:IPR044642|dip:DIP-903N|rcsb pdb:3JCM|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|mint:P47093 psi-mi:"MI:0469"(intact) crc64:74FE40A4509CEF33 crc64:B6E37F585B6292EA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:JQtrhOkngO6APIPCFMRnKogB96c559292 rogid:+X6fjvb8flf36BcPKxtclUwNMSY559292 intact-crc:2289A26CCB8F2B5A|rigid:eNes0vF7GtcQpkRPHTsKpFMNO7c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32610 uniprotkb:P47104 intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W intact:EBI-25471|uniprotkb:D6VWK6|ensemblfungi:YJR033C psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym) psi-mi:rav1_yeast(display_long)|uniprotkb:YJR033C(locus name)|uniprotkb:J1590(orf name)|uniprotkb:Suppression of the onset of impotence protein 3(gene name synonym)|uniprotkb:RAV1(gene name)|psi-mi:RAV1(display_short)|uniprotkb:SOI3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334609|imex:IM-14275-1880 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610 sgd:S000003794|refseq:NP_012567.3|mint:P47104|dip:DIP-916N|ensemblfungi:YJR033C(gene)|ensemblfungi:YJR033C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0012505"(endomembrane system)|go:"GO:0015031"(protein transport)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043291"(RAVE complex)|go:"GO:0045022"(early endosome to late endosome transport)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022033|interpro:IPR036322 psi-mi:"MI:0469"(intact) crc64:FDE93E1FAF0AEC5B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292 rogid:HqBGV2QEc0jU73X3f9brym6t4NE559292 intact-crc:FFE1C084EA7E5FA8|rigid:GfPzgS6/IbraDTP/VfGiFtkbDAY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47120 uniprotkb:P34244 intact:EBI-25526|uniprotkb:D6VWP1|ensemblfungi:YJR070C intact:EBI-9771|uniprotkb:A2NP40|ensemblfungi:YKL101W|uniprotkb:D6VXI6 psi-mi:dohh_yeast(display_long)|uniprotkb:YJR070C(locus name)|uniprotkb:J1814(orf name)|uniprotkb:Deoxyhypusine monooxygenase(gene name synonym)|uniprotkb:Ligand of eIF5A protein 1(gene name synonym)|uniprotkb:Deoxyhypusine dioxygenase(gene name synonym)|uniprotkb:LIA1(gene name)|psi-mi:LIA1(display_short)|uniprotkb:MMD1(gene name synonym) psi-mi:hsl1_yeast(display_long)|uniprotkb:YKL453(orf name)|uniprotkb:YKL101W(locus name)|uniprotkb:HSL1(gene name)|psi-mi:HSL1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334620|imex:IM-14275-1881 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012604.1|sgd:S000003831|mint:P47120|dip:DIP-2829N|ensemblfungi:YJR070C(gene)|ensemblfungi:YJR070C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008612"(peptidyl-lysine modification to peptidyl-hypusine)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019135"(deoxyhypusine monooxygenase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR004155(PBS lyase HEAT-like repeat)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027517|reactome:R-SCE-204626 refseq:NP_012821.2|sgd:S000001584|ensemblfungi:YKL101W(gene)|ensemblfungi:YKL101W_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044879"(mitotic morphogenesis checkpoint signaling)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902935"(protein localization to septin ring)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:5G04|rcsb pdb:5KHR|rcsb pdb:5L9T|rcsb pdb:5L9U|go:"GO:0000144"(cellular bud neck septin ring)|dip:DIP-3022N|mint:P34244 psi-mi:"MI:0469"(intact) crc64:AB36A73B40466CD5 crc64:803F84F7574304CD figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZqdyFodW8hqdOsOgIizarhUDHKY559292 rogid:9lnAFjeIZjowGo5Vxj/3sb/bLys559292 intact-crc:92E3056EDA78DEDF|rigid:Kp8V/e3HYRfdt3mmjeesl/WiUoE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47120 uniprotkb:P50873 intact:EBI-25526|uniprotkb:D6VWP1|ensemblfungi:YJR070C intact:EBI-2069747|uniprotkb:D6VRS0|uniprotkb:Q07470|ensemblfungi:YDL079C psi-mi:dohh_yeast(display_long)|uniprotkb:YJR070C(locus name)|uniprotkb:J1814(orf name)|uniprotkb:Deoxyhypusine monooxygenase(gene name synonym)|uniprotkb:Ligand of eIF5A protein 1(gene name synonym)|uniprotkb:Deoxyhypusine dioxygenase(gene name synonym)|uniprotkb:LIA1(gene name)|psi-mi:LIA1(display_short)|uniprotkb:MMD1(gene name synonym) psi-mi:mrk1_yeast(display_long)|uniprotkb:MRK1(gene name)|psi-mi:MRK1(display_short)|uniprotkb:YDL079C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334631|imex:IM-14275-1882 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012604.1|sgd:S000003831|mint:P47120|dip:DIP-2829N|ensemblfungi:YJR070C(gene)|ensemblfungi:YJR070C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008612"(peptidyl-lysine modification to peptidyl-hypusine)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019135"(deoxyhypusine monooxygenase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR004155(PBS lyase HEAT-like repeat)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027517|reactome:R-SCE-204626 refseq:NP_010204.1|sgd:S000002237|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|mint:P50873|interpro:IPR039192|ensemblfungi:YDL079C(gene)|ensemblfungi:YDL079C_mRNA(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|reactome:R-SCE-3371453 psi-mi:"MI:0469"(intact) crc64:AB36A73B40466CD5 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZqdyFodW8hqdOsOgIizarhUDHKY559292 rogid:7HSmbBh1hnF+ykeOv69YtFCWugI559292 intact-crc:A18202A8F7606009|rigid:1c9JSY0Yr4GkAtqczpZ3NRSiOe8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47122 uniprotkb:P08518 intact:EBI-25534|uniprotkb:D6VWP2|ensemblfungi:YJR072C intact:EBI-15767|uniprotkb:Q12738|uniprotkb:Q7Z9Y0|uniprotkb:D6W2K8|ensemblfungi:YOR151C psi-mi:gpn1_yeast(display_long)|uniprotkb:Essential PCL1-interacting ATPase 1(gene name synonym)|uniprotkb:NPA3(gene name)|psi-mi:NPA3(display_short)|uniprotkb:EPA1(gene name synonym)|uniprotkb:GPN-loop GTPase NPA3(gene name synonym)|uniprotkb:GPN1(gene name synonym)|uniprotkb:Nucleolar preribosomal-associated protein 3(gene name synonym)|uniprotkb:J1821(orf name)|uniprotkb:YJR072C(locus name) psi-mi:rpb2_yeast(display_long)|uniprotkb:YOR151C(locus name)|uniprotkb:RPB2(gene name)|psi-mi:RPB2(display_short)|uniprotkb:RPB150(gene name synonym)|uniprotkb:RPO22(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym)|uniprotkb:B150(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334642|imex:IM-14275-1883 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003833|refseq:NP_012606.3|mint:P47122|dip:DIP-1676N|ensemblfungi:YJR072C(gene)|ensemblfungi:YJR072C_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0016887"(ATP hydrolysis activity)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030230|rcsb pdb:5HCI|rcsb pdb:5HCN sgd:S000005677|refseq:NP_014794.3|dip:DIP-14N|mint:P08518|ensemblfungi:YOR151C(gene)|ensemblfungi:YOR151C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) crc64:EA271D14EA1FFAEF crc64:BABD03212C0A583E figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jVQAYnGanqJpbgSZnYRez51Eh7A559292 rogid:OtaUDREazRORKDcfBajDLPlXovY559292 intact-crc:4332FEF832CD5BE8|rigid:CqcsE80YWmQXFQRGnaf+TjiVSDw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47138 uniprotkb:P40487 intact:EBI-25576|uniprotkb:D6VWR6|ensemblfungi:YJR097W intact:EBI-25162|uniprotkb:D6VVI4|ensemblfungi:YIL103W psi-mi:dph4_yeast(display_long)|uniprotkb:JJJ3(gene name)|psi-mi:JJJ3(display_short)|uniprotkb:YJR097W(locus name)|uniprotkb:J protein type 3(gene name synonym)|uniprotkb:J1931(orf name)|uniprotkb:DPH4(gene name synonym) psi-mi:dph1_yeast(display_long)|uniprotkb:DPH1(gene name)|psi-mi:DPH1(display_short)|uniprotkb:Diphthamide biosynthesis protein 1(gene name synonym)|uniprotkb:Diphtheria toxin resistance protein 1(gene name synonym)|uniprotkb:"S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1"(gene name synonym)|uniprotkb:YIL103W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334653|imex:IM-14275-1884 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003858|refseq:NP_012631.3|mint:P47138|dip:DIP-4356N|ensemblfungi:YJR097W(gene)|ensemblfungi:YJR097W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR007872(Zinc finger, DPH-type)|interpro:IPR036671|interpro:IPR036869 refseq:NP_012163.1|sgd:S000001365|mint:P40487|dip:DIP-5653N|ensemblfungi:YIL103W(gene)|ensemblfungi:YIL103W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|go:"GO:0090560"("2-(3-amino-3-carboxypropyl)histidine synthase activity")|interpro:IPR016435(Diphthamide synthesis, DHP1)|interpro:IPR035435|interpro:IPR042263|interpro:IPR042264|interpro:IPR042265|reactome:R-SCE-5358493 psi-mi:"MI:0469"(intact) - crc64:22E93852E03C6722 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:O7j8qSTioKAGsiYvDJzqSF02MpU559292 rogid:zk1Esuvz7u5GtymKbFzfv+PFAPQ559292 intact-crc:C4569A610C50C7BC|rigid:SRZxQST2F12IQaPc3mFPQepMOxk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CX10 uniprotkb:P47146 intact:EBI-6315262|ensemblfungi:YOR393W|ensemblfungi:YPL281C|uniprotkb:D6W385|uniprotkb:Q12007|uniprotkb:Q7LGJ4 intact:EBI-25611|uniprotkb:D6VWS7|ensemblfungi:YJR108W psi-mi:err1_yeast(display_long)|uniprotkb:ERR1(gene name)|psi-mi:ERR1(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:2-phosphoglycerate dehydratase(gene name synonym)|uniprotkb:YOR393W(locus name) psi-mi:abm1_yeast(display_long)|uniprotkb:ABM1(gene name)|psi-mi:ABM1(display_short)|uniprotkb:J1988(orf name)|uniprotkb:YJR108W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334664|imex:IM-14275-1885 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR393W(gene)|ensemblfungi:YOR393W_mRNA(transcript)|ensemblfungi:YPL281C(gene)|ensemblfungi:YPL281C_mRNA(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0006096"(glycolytic process)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|reactome:R-SCE-70171|reactome:R-SCE-70263|mint:P0CX10|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|refseq:NP_015038.1|refseq:NP_015042.1|sgd:S000005920|interpro:IPR029017|interpro:IPR036849 sgd:S000003869|refseq:NP_012642.1|mint:P47146|dip:DIP-5043N|ensemblfungi:YJR108W(gene)|ensemblfungi:YJR108W_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization) psi-mi:"MI:0469"(intact) - crc64:6BADF1E0D50FB3CE figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Vusa5LQZe98ke/mcTRdEnXReZDc559292 rogid:eVAyFhWvVwpJaPAOnavje+/n+08559292 intact-crc:B2414C349B1168FE|rigid:tJUIQFGAe4T7jPNzovhwv7tcgyI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47146 uniprotkb:P53271 intact:EBI-25611|uniprotkb:D6VWS7|ensemblfungi:YJR108W intact:EBI-16614|ensemblfungi:YGR120C|uniprotkb:D6VUQ1 psi-mi:abm1_yeast(display_long)|uniprotkb:ABM1(gene name)|psi-mi:ABM1(display_short)|uniprotkb:J1988(orf name)|uniprotkb:YJR108W(locus name) psi-mi:cog2_yeast(display_long)|uniprotkb:COG2(gene name)|psi-mi:COG2(display_short)|uniprotkb:SEC35(gene name synonym)|uniprotkb:YGR120C(locus name)|uniprotkb:G6324(orf name)|uniprotkb:Component of oligomeric Golgi complex 2(gene name synonym)|uniprotkb:Protein SEC35(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334675|imex:IM-14275-1886 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003869|refseq:NP_012642.1|mint:P47146|dip:DIP-5043N|ensemblfungi:YJR108W(gene)|ensemblfungi:YJR108W_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization) ensemblfungi:YGR120C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|ensemblfungi:YGR120C(gene)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|interpro:IPR024602|rcsb pdb:2JQQ|refseq:NP_011635.2|sgd:S000003352|dip:DIP-1194N|mint:P53271 psi-mi:"MI:0469"(intact) crc64:6BADF1E0D50FB3CE crc64:0ED457A7466F0F53 figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:eVAyFhWvVwpJaPAOnavje+/n+08559292 rogid:z6RCRJ5cOxonAP7jlL9bN7KLD/c559292 intact-crc:8F5FA005A4529659|rigid:/h+zo1H3K5amj5QvS+ZftUhcy8I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3E776 uniprotkb:P47146 intact:EBI-2042805|uniprotkb:D6VQQ2|ensemblfungi:YBR255C-A intact:EBI-25611|uniprotkb:D6VWS7|ensemblfungi:YJR108W psi-mi:yb255_yeast(display_long)|uniprotkb:YBR255C-A(locus name) psi-mi:abm1_yeast(display_long)|uniprotkb:ABM1(gene name)|psi-mi:ABM1(display_short)|uniprotkb:J1988(orf name)|uniprotkb:YJR108W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334686|imex:IM-14275-1887 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000007649|interpro:IPR038882|refseq:NP_116328.4|mint:Q3E776|ensemblfungi:YBR255C-A(gene)|ensemblfungi:YBR255C-A_mRNA(transcript)|go:"GO:0016021"(integral component of membrane) sgd:S000003869|refseq:NP_012642.1|mint:P47146|dip:DIP-5043N|ensemblfungi:YJR108W(gene)|ensemblfungi:YJR108W_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization) psi-mi:"MI:0469"(intact) - crc64:6BADF1E0D50FB3CE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:LHd4ToffLuVn2nuqg93EsoO8ouo559292 rogid:eVAyFhWvVwpJaPAOnavje+/n+08559292 intact-crc:C1367C86A68903F3|rigid:Z3j4hUzH7F2riUyCaUmqUiUlxAk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47146 uniprotkb:Q8TGU5 intact:EBI-25611|uniprotkb:D6VWS7|ensemblfungi:YJR108W intact:EBI-2042814|uniprotkb:D6VQU1|ensemblfungi:YBR296C-A psi-mi:abm1_yeast(display_long)|uniprotkb:ABM1(gene name)|psi-mi:ABM1(display_short)|uniprotkb:J1988(orf name)|uniprotkb:YJR108W(locus name) psi-mi:yb296_yeast(display_long)|uniprotkb:YBR296C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334697|imex:IM-14275-1888 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003869|refseq:NP_012642.1|mint:P47146|dip:DIP-5043N|ensemblfungi:YJR108W(gene)|ensemblfungi:YJR108W_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization) sgd:S000028605|refseq:NP_878055.3|mint:Q8TGU5|ensemblfungi:YBR296C-A(gene)|ensemblfungi:YBR296C-A_mRNA(transcript)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity) psi-mi:"MI:0469"(intact) crc64:6BADF1E0D50FB3CE - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:eVAyFhWvVwpJaPAOnavje+/n+08559292 rogid:DZubWD7lnwtea4Ne/bK1ITPFaJk559292 intact-crc:CCE93B3C42F23C54|rigid:WnPoMsvGMHi57N7kcNUkyuCP5GE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47149 uniprotkb:P06776 intact:EBI-12098|uniprotkb:Q06779|uniprotkb:D6VWT1|ensemblfungi:YJR112W intact:EBI-4780|uniprotkb:Q08836|uniprotkb:D6W355|ensemblfungi:YOR360C psi-mi:nnf1_yeast(display_long)|uniprotkb:J2011(orf name)|uniprotkb:YJR112W(locus name)|uniprotkb:NNF1(gene name)|psi-mi:NNF1(display_short) psi-mi:pde2_yeast(display_long)|uniprotkb:PDE2(gene name)|psi-mi:PDE2(display_short)|uniprotkb:SRA5(gene name synonym)|uniprotkb:YOR360C(locus name)|uniprotkb:High-affinity cAMP phosphodiesterase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334708|imex:IM-14275-1889 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YJR112W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|interpro:IPR007128(Nnf1)|interpro:IPR016851(Kinetochore-associated protein Nnf1p)|ensemblfungi:YJR112W(gene)|refseq:NP_012646.3|sgd:S000003873|mint:P47149|dip:DIP-3017N refseq:NP_015005.1|sgd:S000005887|dip:DIP-4055N|mint:P06776|ensemblfungi:YOR360C(gene)|ensemblfungi:YOR360C_mRNA(transcript)|go:"GO:0004114"(3',5'-cyclic-nucleotide phosphodiesterase activity)|go:"GO:0004115"(3',5'-cyclic-AMP phosphodiesterase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0046872"(metal ion binding)|interpro:IPR002073(3'5'-cyclic nucleotide phosphodiesterase)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR023088|interpro:IPR023174|interpro:IPR036971|reactome:R-SCE-418457|reactome:R-SCE-418555 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fveaY324dma1QT0Cugtm+8PPV2A559292 rogid:8I+yKEcjCVFgenC1RIzic2Iqb5M559292 intact-crc:7A9E8589D8F0B02D|rigid:nTgw2UYa2IVAfwtjifKzKUSQMoI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47154 uniprotkb:P10614 intact:EBI-18298|uniprotkb:D6VWT6|ensemblfungi:YJR117W intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:ste24_yeast(display_long)|uniprotkb:STE24(gene name)|psi-mi:STE24(display_short)|uniprotkb:AFC1(gene name synonym)|uniprotkb:YJR117W(locus name)|uniprotkb:J2032(orf name)|uniprotkb:Prenyl protein-specific endoprotease 1(gene name synonym)|uniprotkb:A-factor-converting enzyme(gene name synonym) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334719|imex:IM-14275-1890 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012651.1|sgd:S000003878|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016485"(protein processing)|go:"GO:0019236"(response to pheromone)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0071432"(peptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion)|go:"GO:0071586"(CAAX-box protein processing)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR001915(Peptidase M48, Ste24p)|interpro:IPR027057|interpro:IPR032456|go:"GO:0005637"(nuclear inner membrane)|ensemblfungi:YJR117W(gene)|ensemblfungi:YJR117W_mRNA(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|dip:DIP-1390N|mint:P47154 refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HElgJQdYMPeUIEgcRxlHUnBCkgQ559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:2B46BEAD632A12F4|rigid:wB5FuHCDCqKm+K7yq6qe1wJLXOo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47154 uniprotkb:P16603 intact:EBI-18298|uniprotkb:D6VWT6|ensemblfungi:YJR117W intact:EBI-11940|ensemblfungi:YHR042W|uniprotkb:D3DKZ0 psi-mi:ste24_yeast(display_long)|uniprotkb:STE24(gene name)|psi-mi:STE24(display_short)|uniprotkb:AFC1(gene name synonym)|uniprotkb:YJR117W(locus name)|uniprotkb:J2032(orf name)|uniprotkb:Prenyl protein-specific endoprotease 1(gene name synonym)|uniprotkb:A-factor-converting enzyme(gene name synonym) psi-mi:ncpr_yeast(display_long)|uniprotkb:NCP1(gene name)|psi-mi:NCP1(display_short)|uniprotkb:NCPR1(gene name synonym)|uniprotkb:PRD1(gene name synonym)|uniprotkb:CPR1(gene name synonym)|uniprotkb:YHR042W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334730|imex:IM-14275-1891 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012651.1|sgd:S000003878|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016485"(protein processing)|go:"GO:0019236"(response to pheromone)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0071432"(peptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion)|go:"GO:0071586"(CAAX-box protein processing)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR001915(Peptidase M48, Ste24p)|interpro:IPR027057|interpro:IPR032456|go:"GO:0005637"(nuclear inner membrane)|ensemblfungi:YJR117W(gene)|ensemblfungi:YJR117W_mRNA(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|dip:DIP-1390N|mint:P47154 ensemblfungi:YHR042W(gene)|ensemblfungi:YHR042W_mRNA(transcript)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0003959"(NADPH dehydrogenase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0010181"(FMN binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0005739"(mitochondrion)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR023208|interpro:IPR039261|rcsb pdb:2BF4|rcsb pdb:2BN4|rcsb pdb:2BPO|rcsb pdb:3FJO|reactome:R-SCE-1222556|reactome:R-SCE-1474151|reactome:R-SCE-203615|reactome:R-SCE-392154|reactome:R-SCE-5218920|reactome:R-SCE-5578775|reactome:R-SCE-9009391|reactome:R-SCE-9033241|interpro:IPR029039|refseq:NP_011908.1|sgd:S000001084|mint:P16603|dip:DIP-8294N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HElgJQdYMPeUIEgcRxlHUnBCkgQ559292 rogid:l8faixht4sd0KQhbt2DadH/8BPw559292 intact-crc:5F21DDF455FBB92D|rigid:K/epm65iwLiZzD2jiKsK1KoPhNA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:P47154 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-18298|uniprotkb:D6VWT6|ensemblfungi:YJR117W psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:ste24_yeast(display_long)|uniprotkb:STE24(gene name)|psi-mi:STE24(display_short)|uniprotkb:AFC1(gene name synonym)|uniprotkb:YJR117W(locus name)|uniprotkb:J2032(orf name)|uniprotkb:Prenyl protein-specific endoprotease 1(gene name synonym)|uniprotkb:A-factor-converting enzyme(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334741|imex:IM-14275-1892 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N refseq:NP_012651.1|sgd:S000003878|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016485"(protein processing)|go:"GO:0019236"(response to pheromone)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0071432"(peptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion)|go:"GO:0071586"(CAAX-box protein processing)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR001915(Peptidase M48, Ste24p)|interpro:IPR027057|interpro:IPR032456|go:"GO:0005637"(nuclear inner membrane)|ensemblfungi:YJR117W(gene)|ensemblfungi:YJR117W_mRNA(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|dip:DIP-1390N|mint:P47154 psi-mi:"MI:0469"(intact) crc64:8B7F009521F72C15 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:HElgJQdYMPeUIEgcRxlHUnBCkgQ559292 intact-crc:B3F17DC82E4EBAA5|rigid:516taeg7Jd63nLL54Tpm0HAkA9o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47154 uniprotkb:P38264 intact:EBI-18298|uniprotkb:D6VWT6|ensemblfungi:YJR117W intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 psi-mi:ste24_yeast(display_long)|uniprotkb:STE24(gene name)|psi-mi:STE24(display_short)|uniprotkb:AFC1(gene name synonym)|uniprotkb:YJR117W(locus name)|uniprotkb:J2032(orf name)|uniprotkb:Prenyl protein-specific endoprotease 1(gene name synonym)|uniprotkb:A-factor-converting enzyme(gene name synonym) psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334752|imex:IM-14275-1893 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012651.1|sgd:S000003878|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016485"(protein processing)|go:"GO:0019236"(response to pheromone)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0071432"(peptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion)|go:"GO:0071586"(CAAX-box protein processing)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR001915(Peptidase M48, Ste24p)|interpro:IPR027057|interpro:IPR032456|go:"GO:0005637"(nuclear inner membrane)|ensemblfungi:YJR117W(gene)|ensemblfungi:YJR117W_mRNA(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|dip:DIP-1390N|mint:P47154 refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HElgJQdYMPeUIEgcRxlHUnBCkgQ559292 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 intact-crc:3C50BC7BBE0AAE39|rigid:MGyFhqqX7ya6vzC0VXvxVbDWSQs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47154 uniprotkb:P40540 intact:EBI-18298|uniprotkb:D6VWT6|ensemblfungi:YJR117W intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C psi-mi:ste24_yeast(display_long)|uniprotkb:STE24(gene name)|psi-mi:STE24(display_short)|uniprotkb:AFC1(gene name synonym)|uniprotkb:YJR117W(locus name)|uniprotkb:J2032(orf name)|uniprotkb:Prenyl protein-specific endoprotease 1(gene name synonym)|uniprotkb:A-factor-converting enzyme(gene name synonym) psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334763|imex:IM-14275-1894 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012651.1|sgd:S000003878|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016485"(protein processing)|go:"GO:0019236"(response to pheromone)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0071432"(peptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion)|go:"GO:0071586"(CAAX-box protein processing)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR001915(Peptidase M48, Ste24p)|interpro:IPR027057|interpro:IPR032456|go:"GO:0005637"(nuclear inner membrane)|ensemblfungi:YJR117W(gene)|ensemblfungi:YJR117W_mRNA(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|dip:DIP-1390N|mint:P47154 refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) - crc64:6DBEEEE7722203B0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HElgJQdYMPeUIEgcRxlHUnBCkgQ559292 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 intact-crc:CFD818ED65892B99|rigid:8+vQf1hb5ERRDiQGINo3+cQ8vaE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P47155 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-2051644|uniprotkb:D6VWT7|ensemblfungi:YJR118C psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:ilm1_yeast(display_long)|uniprotkb:Increased loss of mitochondrial DNA protein 1(gene name synonym)|uniprotkb:J2033(orf name)|uniprotkb:ILM1(gene name)|psi-mi:ILM1(display_short)|uniprotkb:YJR118C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334774|imex:IM-14275-1895 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 sgd:S000003879|interpro:IPR018815|refseq:NP_012652.3|mint:P47155|ensemblfungi:YJR118C(gene)|ensemblfungi:YJR118C_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:BrQhbXGvUjNG6Bt5c0J7T8qzMeI559292 intact-crc:B4FFB58B46DE4CA0|rigid:X7JUREYH76vqG91P7weK48zSFWs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47155 uniprotkb:P38264 intact:EBI-2051644|uniprotkb:D6VWT7|ensemblfungi:YJR118C intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 psi-mi:ilm1_yeast(display_long)|uniprotkb:Increased loss of mitochondrial DNA protein 1(gene name synonym)|uniprotkb:J2033(orf name)|uniprotkb:ILM1(gene name)|psi-mi:ILM1(display_short)|uniprotkb:YJR118C(locus name) psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334785|imex:IM-14275-1896 author score:98.11 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003879|interpro:IPR018815|refseq:NP_012652.3|mint:P47155|ensemblfungi:YJR118C(gene)|ensemblfungi:YJR118C_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.11|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BrQhbXGvUjNG6Bt5c0J7T8qzMeI559292 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 intact-crc:A3E806ED9A4EF06D|rigid:tWgxZ+tA+8z7wUvMerPE0ys31JY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47155 uniprotkb:P47155 intact:EBI-2051644|uniprotkb:D6VWT7|ensemblfungi:YJR118C intact:EBI-2051644|uniprotkb:D6VWT7|ensemblfungi:YJR118C psi-mi:ilm1_yeast(display_long)|uniprotkb:Increased loss of mitochondrial DNA protein 1(gene name synonym)|uniprotkb:J2033(orf name)|uniprotkb:ILM1(gene name)|psi-mi:ILM1(display_short)|uniprotkb:YJR118C(locus name) psi-mi:ilm1_yeast(display_long)|uniprotkb:Increased loss of mitochondrial DNA protein 1(gene name synonym)|uniprotkb:J2033(orf name)|uniprotkb:ILM1(gene name)|psi-mi:ILM1(display_short)|uniprotkb:YJR118C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334796|imex:IM-14275-1897 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003879|interpro:IPR018815|refseq:NP_012652.3|mint:P47155|ensemblfungi:YJR118C(gene)|ensemblfungi:YJR118C_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane) sgd:S000003879|interpro:IPR018815|refseq:NP_012652.3|mint:P47155|ensemblfungi:YJR118C(gene)|ensemblfungi:YJR118C_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BrQhbXGvUjNG6Bt5c0J7T8qzMeI559292 rogid:BrQhbXGvUjNG6Bt5c0J7T8qzMeI559292 intact-crc:B184E1C212202B45|rigid:7JbFVdPzudiEs08bWIt8+OkF5OA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04201 uniprotkb:P47155 intact:EBI-27928|uniprotkb:D6W0I3|ensemblfungi:YML101C intact:EBI-2051644|uniprotkb:D6VWT7|ensemblfungi:YJR118C psi-mi:cue4_yeast(display_long)|uniprotkb:YML101C(locus name)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 4(gene name synonym)|uniprotkb:CUE4(gene name)|psi-mi:CUE4(display_short) psi-mi:ilm1_yeast(display_long)|uniprotkb:Increased loss of mitochondrial DNA protein 1(gene name synonym)|uniprotkb:J2033(orf name)|uniprotkb:ILM1(gene name)|psi-mi:ILM1(display_short)|uniprotkb:YJR118C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334807|imex:IM-14275-1898 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013607.1|sgd:S000004568|dip:DIP-4525N|mint:Q04201|ensemblfungi:YML101C(gene)|ensemblfungi:YML101C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue) sgd:S000003879|interpro:IPR018815|refseq:NP_012652.3|mint:P47155|ensemblfungi:YJR118C(gene)|ensemblfungi:YJR118C_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:NMBJHZbX4/gU01fk4evPDXm/M6w559292 rogid:BrQhbXGvUjNG6Bt5c0J7T8qzMeI559292 intact-crc:7E5C91ACC28FE6D0|rigid:sXNt0o1mKPjrW45LOIb1HxjZg08 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47158 uniprotkb:P48564 intact:EBI-25654|uniprotkb:D6VWU1|ensemblfungi:YJR122W intact:EBI-2046889|uniprotkb:D6W0P8|ensemblfungi:YNL295W psi-mi:caf17_yeast(display_long)|uniprotkb:YJR122W(locus name)|uniprotkb:J2043(orf name)|uniprotkb:IBA57(gene name)|psi-mi:IBA57(display_short)|uniprotkb:CCR4-associated factor 17(gene name synonym)|uniprotkb:CAF17(gene name synonym)|uniprotkb:57 kDa iron-sulfur cluster assembly factor for biotin synthase- and aconitase-like mitochondrial proteins(gene name synonym) psi-mi:mrx6_yeast(display_long)|uniprotkb:Mitochondrial organization of gene expression protein 6(gene name synonym)|uniprotkb:MRX6(gene name)|psi-mi:MRX6(display_short)|uniprotkb:N0462(orf name)|uniprotkb:YNL295W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334818|imex:IM-14275-1899 author score:99.26 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012656.1|sgd:S000003883|mint:P47158|dip:DIP-1404N|ensemblfungi:YJR122W(gene)|ensemblfungi:YJR122W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016740"(transferase activity)|go:"GO:0106034"(protein maturation by [2Fe-2S] cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR017703(Folate-binding, YgfZ) sgd:S000005239|interpro:IPR014804(Mitochondrial protein Pet20)|refseq:NP_014104.1|mint:P48564|ensemblfungi:YNL295W(gene)|ensemblfungi:YNL295W_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0090144"(mitochondrial nucleoid organization)|go:"GO:1901858"(regulation of mitochondrial DNA metabolic process) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.26|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TYbcguOnZonMy37jWe6OtiYO07k559292 rogid:tn8uhrqTB1ab8+RUwgjWLjJ9b8w559292 intact-crc:AE5BC02D351906AE|rigid:22sGB5uHY/objqDR2QfOycRqeAA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47158 uniprotkb:Q8TGJ2 intact:EBI-25654|uniprotkb:D6VWU1|ensemblfungi:YJR122W intact:EBI-2047109|uniprotkb:D6W1Q1|ensemblfungi:YNR075C-A psi-mi:caf17_yeast(display_long)|uniprotkb:YJR122W(locus name)|uniprotkb:J2043(orf name)|uniprotkb:IBA57(gene name)|psi-mi:IBA57(display_short)|uniprotkb:CCR4-associated factor 17(gene name synonym)|uniprotkb:CAF17(gene name synonym)|uniprotkb:57 kDa iron-sulfur cluster assembly factor for biotin synthase- and aconitase-like mitochondrial proteins(gene name synonym) psi-mi:yn075_yeast(display_long)|uniprotkb:YNR075C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334829|imex:IM-14275-1900 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012656.1|sgd:S000003883|mint:P47158|dip:DIP-1404N|ensemblfungi:YJR122W(gene)|ensemblfungi:YJR122W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016740"(transferase activity)|go:"GO:0106034"(protein maturation by [2Fe-2S] cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR017703(Folate-binding, YgfZ) sgd:S000028706|refseq:NP_878159.3|mint:Q8TGJ2|ensemblfungi:YNR075C-A(gene)|ensemblfungi:YNR075C-A_mRNA(transcript) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TYbcguOnZonMy37jWe6OtiYO07k559292 rogid:a2YkRms9fcm6XZTy1Q74gRGCXPY559292 intact-crc:7A3ECFFA7AD26772|rigid:tvhZkEJAQZJw4XIF0p+EXBx/ZEA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47165 uniprotkb:P47165 intact:EBI-25682|uniprotkb:D6VWV1|ensemblfungi:YJR133W intact:EBI-25682|uniprotkb:D6VWV1|ensemblfungi:YJR133W psi-mi:xpt1_yeast(display_long)|uniprotkb:XPT1(gene name)|psi-mi:XPT1(display_short)|uniprotkb:J2118(orf name)|uniprotkb:YJR133W(locus name) psi-mi:xpt1_yeast(display_long)|uniprotkb:XPT1(gene name)|psi-mi:XPT1(display_short)|uniprotkb:J2118(orf name)|uniprotkb:YJR133W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334840|imex:IM-14275-1901 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012667.1|sgd:S000003894|mint:P47165|dip:DIP-1576N|ensemblfungi:YJR133W(gene)|ensemblfungi:YJR133W_mRNA(transcript)|go:"GO:0000310"(xanthine phosphoribosyltransferase activity)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0004615"(phosphomannomutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0032265"(XMP salvage)|go:"GO:0046100"(hypoxanthine metabolic process)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057 refseq:NP_012667.1|sgd:S000003894|mint:P47165|dip:DIP-1576N|ensemblfungi:YJR133W(gene)|ensemblfungi:YJR133W_mRNA(transcript)|go:"GO:0000310"(xanthine phosphoribosyltransferase activity)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0004615"(phosphomannomutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0032265"(XMP salvage)|go:"GO:0046100"(hypoxanthine metabolic process)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hjdGDsZ62F5m8o7QAcZMoVVXWVc559292 rogid:hjdGDsZ62F5m8o7QAcZMoVVXWVc559292 intact-crc:93C72ADF7589BD0F|rigid:jsNT9XS6X3zFbHww84UbKTAHsLA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39968 uniprotkb:P47170 intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W intact:EBI-25710|uniprotkb:D6VWV7|ensemblfungi:YJR138W psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name) psi-mi:iml1_yeast(display_long)|uniprotkb:IML1(gene name)|psi-mi:IML1(display_short)|uniprotkb:Increased minichromosome loss protein 1(gene name synonym)|uniprotkb:SEA1(gene name synonym)|uniprotkb:SEH-associated protein 1(gene name synonym)|uniprotkb:J2129(orf name)|uniprotkb:YJR138W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334851|imex:IM-14275-1902 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N refseq:NP_012672.1|sgd:S000003899|mint:P47170|dip:DIP-2589N|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035859"(Seh1-associated complex)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0097042"(extrinsic component of fungal-type vacuolar membrane)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1990130"(GATOR1 complex)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR027244|interpro:IPR036388|interpro:IPR036390|ensemblfungi:YJR138W(gene)|ensemblfungi:YJR138W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0032007"(negative regulation of TOR signaling) psi-mi:"MI:0469"(intact) crc64:B2E75774B47E5933 crc64:BB8E73FF5B70CCDF figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292 rogid:h0cf/P1VAxXdA23g7gmNsd/L3Ag559292 intact-crc:65B8D5C37B92B435|rigid:a158guiAUo8hhwtyjVsRe1um9FI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04049 uniprotkb:P48353 intact:EBI-36214|uniprotkb:D6VT49|ensemblfungi:YDR419W intact:EBI-8369|uniprotkb:D6VZY3|ensemblfungi:YMR161W psi-mi:polh_yeast(display_long)|uniprotkb:RAD30(gene name)|psi-mi:RAD30(display_short)|uniprotkb:DBH1(gene name synonym)|uniprotkb:YDR419W(locus name)|uniprotkb:Radiation-sensitive protein 30(gene name synonym) psi-mi:hlj1_yeast(display_long)|uniprotkb:YM8520.10(orf name)|uniprotkb:YMR161W(locus name)|uniprotkb:HLJ1(gene name)|psi-mi:HLJ1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334862|imex:IM-14275-1903 author score:99.36 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002827|refseq:NP_010707.3|mint:Q04049|dip:DIP-6500N|ensemblfungi:YDR419W(gene)|ensemblfungi:YDR419W_mRNA(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0070987"(error-free translesion synthesis)|interpro:IPR001126(UMUC-like DNA-repair protein)|interpro:IPR036775|interpro:IPR041298|interpro:IPR043128|interpro:IPR043502|rcsb pdb:1JIH|rcsb pdb:2R8J|rcsb pdb:2R8K|rcsb pdb:2WTF|rcsb pdb:2XGP|rcsb pdb:2XGQ|rcsb pdb:3MFH|rcsb pdb:3MFI|rcsb pdb:3OHA|rcsb pdb:3OHB|rcsb pdb:5VTP|reactome:R-SCE-110320|reactome:R-SCE-5656169 refseq:NP_013884.1|sgd:S000004771|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:P48353|ensemblfungi:YMR161W(gene)|ensemblfungi:YMR161W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0071218"(cellular response to misfolded protein) psi-mi:"MI:0469"(intact) crc64:CFB1A9FBC8AFE39B - figure legend:tables S3 and S4|author-confidence:99.36|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UezH5s3d7XqG3y3LEglWvRzgzCc559292 rogid:nWoh7gR4ahqDqEP0CDwp2QaAC5c559292 intact-crc:DD9C0427ECEA9F40|rigid:eMSsvR3lPVpf5LL9PY/VhQRIwug false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P52553 uniprotkb:P48363 intact:EBI-13260|uniprotkb:D6VYK2|ensemblfungi:YLR200W intact:EBI-13239|uniprotkb:D6VUL0|ensemblfungi:YGR078C psi-mi:pfd6_yeast(display_long)|uniprotkb:YKE2(gene name)|psi-mi:YKE2(display_short)|uniprotkb:PFD6(gene name synonym)|uniprotkb:YLR200W(locus name)|uniprotkb:L8167.8(orf name)|uniprotkb:GIM1(gene name synonym)|uniprotkb:Genes involved in microtubule biogenesis protein 1(gene name synonym)|uniprotkb:Gim complex subunit 1(gene name synonym) psi-mi:pfd3_yeast(display_long)|uniprotkb:PAC10(gene name)|psi-mi:PAC10(display_short)|uniprotkb:PFD3(gene name synonym)|uniprotkb:GIM2(gene name synonym)|uniprotkb:YGR078C(locus name)|uniprotkb:Genes involved in microtubule biogenesis protein 2(gene name synonym)|uniprotkb:Gim complex subunit 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334873|imex:IM-14275-1904 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013301.1|sgd:S000004190|mint:P52553|dip:DIP-1333N|ensemblfungi:YLR200W(gene)|ensemblfungi:YLR200W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin) refseq:NP_011592.3|sgd:S000003310|mint:P48363|dip:DIP-6837N|ensemblfungi:YGR078C(gene)|ensemblfungi:YGR078C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006457"(protein folding)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016655(Prefoldin, subunit 3) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XXTSrL5Q5CrSqYzKV3j3h5/7d10559292 rogid:PgfsZGjmKc7Kt2dTnjkCzhzQflY559292 intact-crc:A9883BB662C457F4|rigid:ZIHN3d+yiurjgjk2cxtmKjIbZWs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48363 uniprotkb:P53900 intact:EBI-13239|uniprotkb:D6VUL0|ensemblfungi:YGR078C intact:EBI-13246|uniprotkb:D6W130|ensemblfungi:YNL153C psi-mi:pfd3_yeast(display_long)|uniprotkb:PAC10(gene name)|psi-mi:PAC10(display_short)|uniprotkb:PFD3(gene name synonym)|uniprotkb:GIM2(gene name synonym)|uniprotkb:YGR078C(locus name)|uniprotkb:Genes involved in microtubule biogenesis protein 2(gene name synonym)|uniprotkb:Gim complex subunit 2(gene name synonym) psi-mi:pfd4_yeast(display_long)|uniprotkb:GIM3(gene name)|psi-mi:GIM3(display_short)|uniprotkb:PFD4(gene name synonym)|uniprotkb:YNL153C(locus name)|uniprotkb:N1761(orf name)|uniprotkb:Genes involved in microtubule biogenesis protein 3(gene name synonym)|uniprotkb:Gim complex subunit 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334884|imex:IM-14275-1905 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011592.3|sgd:S000003310|mint:P48363|dip:DIP-6837N|ensemblfungi:YGR078C(gene)|ensemblfungi:YGR078C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006457"(protein folding)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016655(Prefoldin, subunit 3) refseq:NP_014246.1|sgd:S000005097|mint:P53900|dip:DIP-3000N|ensemblfungi:YNL153C(gene)|ensemblfungi:YNL153C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016661(Prefoldin, subunit 4) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:PgfsZGjmKc7Kt2dTnjkCzhzQflY559292 rogid:TdRDErsc5xwqaEqpI4SSCW0sCsg559292 intact-crc:F512A9887EC80E78|rigid:WFC8oBesAGlw3IA44SKZr1OOOAU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48363 uniprotkb:Q04493 intact:EBI-13239|uniprotkb:D6VUL0|ensemblfungi:YGR078C intact:EBI-13253|uniprotkb:D6W0J1|ensemblfungi:YML094W psi-mi:pfd3_yeast(display_long)|uniprotkb:PAC10(gene name)|psi-mi:PAC10(display_short)|uniprotkb:PFD3(gene name synonym)|uniprotkb:GIM2(gene name synonym)|uniprotkb:YGR078C(locus name)|uniprotkb:Genes involved in microtubule biogenesis protein 2(gene name synonym)|uniprotkb:Gim complex subunit 2(gene name synonym) psi-mi:pfd5_yeast(display_long)|uniprotkb:GIM5(gene name)|psi-mi:GIM5(display_short)|uniprotkb:PFD5(gene name synonym)|uniprotkb:YML094W(locus name)|uniprotkb:Genes involved in microtubule biogenesis protein 5(gene name synonym)|uniprotkb:Gim complex subunit 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334895|imex:IM-14275-1906 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011592.3|sgd:S000003310|mint:P48363|dip:DIP-6837N|ensemblfungi:YGR078C(gene)|ensemblfungi:YGR078C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006457"(protein folding)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016655(Prefoldin, subunit 3) refseq:NP_013616.1|sgd:S000004559|mint:Q04493|dip:DIP-1332N|ensemblfungi:YML094W(gene)|ensemblfungi:YML094W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR011599(Prefoldin alpha subunit) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:PgfsZGjmKc7Kt2dTnjkCzhzQflY559292 rogid:+I6WXFpL1knsCu3DsbMiC4LqDVo559292 intact-crc:AD19021026624BE2|rigid:y0f7/W2dScxJA6r14mY3tC4JtKY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48524 uniprotkb:P32445 intact:EBI-3881|uniprotkb:D6W0A2|ensemblfungi:YMR275C intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A psi-mi:bul1_yeast(display_long)|uniprotkb:BUL1(gene name)|psi-mi:BUL1(display_short)|uniprotkb:DAG1(gene name synonym)|uniprotkb:RDS1(gene name synonym)|uniprotkb:YMR275C(locus name)|uniprotkb:YM8021.01C(orf name)|uniprotkb:YM8156.17C(orf name)|uniprotkb:SMM2(gene name synonym)|uniprotkb:Respiration deficiency suppressor 1(gene name synonym) psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334906|imex:IM-14275-1907 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004888|refseq:NP_014002.1|dip:DIP-2502N|mint:P48524|ensemblfungi:YMR275C(gene)|ensemblfungi:YMR275C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:1904669"(ATP export)|interpro:IPR007519(Bul1, N-terminal)|interpro:IPR022794|interpro:IPR039634 refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 psi-mi:"MI:0469"(intact) crc64:9253D207B894CE44 crc64:9F913C2FC9EF6E82 figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RKJqBKVm6Mgxmfj/JCXuW0hV1jc559292 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 intact-crc:49E1461332ABFF53|rigid:rjg+Q5yrDZJK8zlFesC1XzEjmDE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48570 uniprotkb:P48570 intact:EBI-8502|uniprotkb:D6VRH0|ensemblfungi:YDL182W intact:EBI-8502|uniprotkb:D6VRH0|ensemblfungi:YDL182W psi-mi:hosc_yeast(display_long)|uniprotkb:D1298(orf name)|uniprotkb:YDL182W(locus name)|uniprotkb:LYS20(gene name)|psi-mi:LYS20(display_short) psi-mi:hosc_yeast(display_long)|uniprotkb:D1298(orf name)|uniprotkb:YDL182W(locus name)|uniprotkb:LYS20(gene name)|psi-mi:LYS20(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334917|imex:IM-14275-1908 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010099.1|sgd:S000002341|interpro:IPR002034(Alpha-isopropylmalate/homocitrate synthase, conserved site)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR011872(Homocitrate synthase, fungi and archaea)|interpro:IPR000891(Pyruvate carboxyltransferase)|mint:P48570|ensemblfungi:YDL182W(gene)|ensemblfungi:YDL182W_mRNA(transcript)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0004410"(homocitrate synthase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0019878"(lysine biosynthetic process via aminoadipic acid)|go:"GO:0046872"(metal ion binding) refseq:NP_010099.1|sgd:S000002341|interpro:IPR002034(Alpha-isopropylmalate/homocitrate synthase, conserved site)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR011872(Homocitrate synthase, fungi and archaea)|interpro:IPR000891(Pyruvate carboxyltransferase)|mint:P48570|ensemblfungi:YDL182W(gene)|ensemblfungi:YDL182W_mRNA(transcript)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0004410"(homocitrate synthase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0019878"(lysine biosynthetic process via aminoadipic acid)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pD1bQgGuaQ2HwmOCaXyXo/i1IvQ559292 rogid:pD1bQgGuaQ2HwmOCaXyXo/i1IvQ559292 intact-crc:129585D4664975BC|rigid:VBbEYvDDHTpI9twoxrZ4bVQBEMs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12122 uniprotkb:P48570 intact:EBI-8508|uniprotkb:E9P8Z7|uniprotkb:D6VRL8|ensemblfungi:YDL131W intact:EBI-8502|uniprotkb:D6VRH0|ensemblfungi:YDL182W psi-mi:hosm_yeast(display_long)|uniprotkb:D2195(orf name)|uniprotkb:YDL131W(locus name)|uniprotkb:LYS21(gene name)|psi-mi:LYS21(display_short) psi-mi:hosc_yeast(display_long)|uniprotkb:D1298(orf name)|uniprotkb:YDL182W(locus name)|uniprotkb:LYS20(gene name)|psi-mi:LYS20(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334928|imex:IM-14275-1909 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010151.1|sgd:S000002289|dip:DIP-4634N|mint:Q12122|ensemblfungi:YDL131W(gene)|ensemblfungi:YDL131W_mRNA(transcript)|go:"GO:0004410"(homocitrate synthase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0019878"(lysine biosynthetic process via aminoadipic acid)|go:"GO:0046872"(metal ion binding)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR002034(Alpha-isopropylmalate/homocitrate synthase, conserved site)|interpro:IPR011872(Homocitrate synthase, fungi and archaea)|interpro:IPR013785(Aldolase-type TIM barrel) refseq:NP_010099.1|sgd:S000002341|interpro:IPR002034(Alpha-isopropylmalate/homocitrate synthase, conserved site)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR011872(Homocitrate synthase, fungi and archaea)|interpro:IPR000891(Pyruvate carboxyltransferase)|mint:P48570|ensemblfungi:YDL182W(gene)|ensemblfungi:YDL182W_mRNA(transcript)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0004410"(homocitrate synthase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0019878"(lysine biosynthetic process via aminoadipic acid)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XA2Z9ramCU3LX1hQw31rwIRjlk8559292 rogid:pD1bQgGuaQ2HwmOCaXyXo/i1IvQ559292 intact-crc:73C735B275C69832|rigid:6mI0RG75yctvdM6G3w5uvEG2Ca0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48837 uniprotkb:P14907 intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0 intact:EBI-12265|uniprotkb:D6VWE3 psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym) psi-mi:nsp1_yeast(display_long)|uniprotkb:NSP1(gene name)|psi-mi:NSP1(display_short)|uniprotkb:YJL041W(locus name)|uniprotkb:J1207(orf name)|uniprotkb:Nuclear pore protein NSP1(gene name synonym)|uniprotkb:Nucleoskeletal-like protein(gene name synonym)|uniprotkb:p110(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334939|imex:IM-14275-1910 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0097064"(ncRNA export from nucleus)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|rcsb pdb:1O6O|refseq:NP_012494.3|sgd:S000003577|mint:P14907|dip:DIP-1484N psi-mi:"MI:0469"(intact) - crc64:A258003CB1917810 figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292 rogid:wFdC6D8JzkhJpF+k3qtnFj9+4pA559292 intact-crc:FE3EEBB6AF981A47|rigid:QQ6nrnkAWhPqiTdhv1cM2qn8wG0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48837 uniprotkb:P48837 intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0 intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0 psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym) psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334950|imex:IM-14275-1911 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292 rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292 intact-crc:59F7618059362E10|rigid:cySE4y7w/NscVn4YCXqBc7NtNMI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48837 uniprotkb:Q02199 intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0 intact:EBI-12315|ensemblfungi:YGL172W|uniprotkb:D6VTY0 psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym) psi-mi:nup49_yeast(display_long)|uniprotkb:NUP49(gene name)|psi-mi:NUP49(display_short)|uniprotkb:NSP49(gene name synonym)|uniprotkb:YGL172W(locus name)|uniprotkb:G1648(orf name)|uniprotkb:Nuclear pore protein NUP49/NSP49(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334961|imex:IM-14275-1912 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N refseq:NP_011343.1|sgd:S000003140|ensemblfungi:YGL172W(gene)|ensemblfungi:YGL172W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR024864|interpro:IPR025574|interpro:IPR039079|mint:Q02199|dip:DIP-709N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292 rogid:2x0Rt5ViHxBEKxPzOcfnyOdgmpg559292 intact-crc:EE9B20E3102AB1A2|rigid:vKpcan76b1yq6a7X0dk226qHI+U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38875 uniprotkb:P49018 intact:EBI-24869|uniprotkb:D3DLD6|ensemblfungi:YHR188C intact:EBI-7822|uniprotkb:D6VSW3|ensemblfungi:YDR331W psi-mi:gpi16_yeast(display_long)|uniprotkb:GPI16(gene name)|psi-mi:GPI16(display_short)|uniprotkb:YHR188C(locus name) psi-mi:gpi8_yeast(display_long)|uniprotkb:GPI8(gene name)|psi-mi:GPI8(display_short)|uniprotkb:D9798.2(orf name)|uniprotkb:YDR331W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334972|imex:IM-14275-1913 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012058.1|sgd:S000001231|mint:P38875|dip:DIP-1888N|ensemblfungi:YHR188C(gene)|ensemblfungi:YHR188C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component) refseq:NP_010618.1|sgd:S000002739|dip:DIP-5371N|mint:P49018|ensemblfungi:YDR331W(gene)|ensemblfungi:YDR331W_mRNA(transcript)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361 psi-mi:"MI:0469"(intact) crc64:E9613CE0EA99F963 - figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:qvK2gNcnfXW5KU81xOCtdz54jgI559292 rogid:5h/ZRVpqdt/EC4pSAd0qlKcUZUk559292 intact-crc:4DE2E61F72434456|rigid:NvZhb9+vHPwn71fUFZJVK3jzw9c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39012 uniprotkb:P49018 intact:EBI-7252|uniprotkb:D6VY88|ensemblfungi:YLR088W intact:EBI-7822|uniprotkb:D6VSW3|ensemblfungi:YDR331W psi-mi:gaa1_yeast(display_long)|uniprotkb:GAA1(gene name)|psi-mi:GAA1(display_short)|uniprotkb:END2(gene name synonym)|uniprotkb:YLR088W(locus name)|uniprotkb:L9449.4(orf name) psi-mi:gpi8_yeast(display_long)|uniprotkb:GPI8(gene name)|psi-mi:GPI8(display_short)|uniprotkb:D9798.2(orf name)|uniprotkb:YDR331W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334983|imex:IM-14275-1914 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013189.1|sgd:S000004078|mint:P39012|dip:DIP-4824N|ensemblfungi:YLR088W(gene)|ensemblfungi:YLR088W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR007246(Gaa1-like, GPI transamidase component) refseq:NP_010618.1|sgd:S000002739|dip:DIP-5371N|mint:P49018|ensemblfungi:YDR331W(gene)|ensemblfungi:YDR331W_mRNA(transcript)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:amv3rxKpKmjGpnjzMInYFQXvlUg559292 rogid:5h/ZRVpqdt/EC4pSAd0qlKcUZUk559292 intact-crc:632D32015B8577B8|rigid:tlnEQS2oj0buMU0fmWL4T0XWVEI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P49018 uniprotkb:Q04080 intact:EBI-7822|uniprotkb:D6VSW3|ensemblfungi:YDR331W intact:EBI-7777|uniprotkb:D6VT61|ensemblfungi:YDR434W psi-mi:gpi8_yeast(display_long)|uniprotkb:GPI8(gene name)|psi-mi:GPI8(display_short)|uniprotkb:D9798.2(orf name)|uniprotkb:YDR331W(locus name) psi-mi:gpi17_yeast(display_long)|uniprotkb:GPI17(gene name)|psi-mi:GPI17(display_short)|uniprotkb:D9461.20(orf name)|uniprotkb:YDR434W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6334994|imex:IM-14275-1915 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010618.1|sgd:S000002739|dip:DIP-5371N|mint:P49018|ensemblfungi:YDR331W(gene)|ensemblfungi:YDR331W_mRNA(transcript)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361 sgd:S000002842|interpro:IPR019540|refseq:NP_010722.3|mint:Q04080|ensemblfungi:YDR434W(gene)|ensemblfungi:YDR434W_mRNA(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5h/ZRVpqdt/EC4pSAd0qlKcUZUk559292 rogid:7bBqUoVPfAOj/Pm4RPbzshzWNr0559292 intact-crc:982094DC71BA0FB8|rigid:n/MZqQkDj5tDIsvxkTGqsnWkg98 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25619 uniprotkb:P49573 intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C intact:EBI-5261|uniprotkb:D6W4C2|ensemblfungi:YPR124W psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:ctr1_yeast(display_long)|uniprotkb:CTR1(gene name)|psi-mi:CTR1(display_short)|uniprotkb:P9642.3(orf name)|uniprotkb:YPR124W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335005|imex:IM-14275-1916 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 refseq:NP_015449.1|sgd:S000006328|dip:DIP-6447N|mint:P49573|ensemblfungi:YPR124W(gene)|ensemblfungi:YPR124W_mRNA(transcript)|go:"GO:0005375"(copper ion transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0015677"(copper ion import)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007274(Ctr copper transporter) psi-mi:"MI:0469"(intact) crc64:260474A481D29AC5 crc64:569C9CB19C1117E8 figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 rogid:ZBHA8DsRaWE20ANtlw2JSfjD8uQ559292 intact-crc:8129BF76A5B43EDB|rigid:hK+M4Fr2yI3erfiphQSLJgCO49U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P49573 uniprotkb:P49573 intact:EBI-5261|uniprotkb:D6W4C2|ensemblfungi:YPR124W intact:EBI-5261|uniprotkb:D6W4C2|ensemblfungi:YPR124W psi-mi:ctr1_yeast(display_long)|uniprotkb:CTR1(gene name)|psi-mi:CTR1(display_short)|uniprotkb:P9642.3(orf name)|uniprotkb:YPR124W(locus name) psi-mi:ctr1_yeast(display_long)|uniprotkb:CTR1(gene name)|psi-mi:CTR1(display_short)|uniprotkb:P9642.3(orf name)|uniprotkb:YPR124W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335016|imex:IM-14275-1917 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015449.1|sgd:S000006328|dip:DIP-6447N|mint:P49573|ensemblfungi:YPR124W(gene)|ensemblfungi:YPR124W_mRNA(transcript)|go:"GO:0005375"(copper ion transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0015677"(copper ion import)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007274(Ctr copper transporter) refseq:NP_015449.1|sgd:S000006328|dip:DIP-6447N|mint:P49573|ensemblfungi:YPR124W(gene)|ensemblfungi:YPR124W_mRNA(transcript)|go:"GO:0005375"(copper ion transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0015677"(copper ion import)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007274(Ctr copper transporter) psi-mi:"MI:0469"(intact) crc64:569C9CB19C1117E8 crc64:569C9CB19C1117E8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZBHA8DsRaWE20ANtlw2JSfjD8uQ559292 rogid:ZBHA8DsRaWE20ANtlw2JSfjD8uQ559292 intact-crc:D31F268D76D41D1F|rigid:mRI+FHk2A5ShushNTFs1d29qwCQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P49687 uniprotkb:P46673 intact:EBI-11730|ensemblfungi:YGL092W|uniprotkb:D6VU53 intact:EBI-12345|ensemblfungi:YJR042W|uniprotkb:D6VWL3 psi-mi:nu145_yeast(display_long)|uniprotkb:YGL092W(locus name)|uniprotkb:NUP145(gene name)|psi-mi:NUP145(display_short)|uniprotkb:RAT10(gene name synonym)|uniprotkb:Nuclear pore protein NUP145(gene name synonym) psi-mi:nup85_yeast(display_long)|uniprotkb:NUP85(gene name)|psi-mi:NUP85(display_short)|uniprotkb:RAT9(gene name synonym)|uniprotkb:YJR042W(locus name)|uniprotkb:J1624(orf name)|uniprotkb:Nuclear pore protein NUP85(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335027|imex:IM-14275-1918 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL092W(gene)|ensemblfungi:YGL092W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003723"(RNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|rcsb pdb:3BG0|rcsb pdb:3BG1|rcsb pdb:3IKO|rcsb pdb:3JRO|rcsb pdb:3JRP|rcsb pdb:3KEP|rcsb pdb:3KES|rcsb pdb:4XMM|rcsb pdb:4XMN|go:"GO:0031509"(subtelomeric heterochromatin assembly)|refseq:NP_011423.1|sgd:S000003060|mint:P49687|dip:DIP-2074N ensemblfungi:YJR042W(gene)|ensemblfungi:YJR042W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR011502(Nucleoporin, Nup85-like)|rcsb pdb:3EWE|rcsb pdb:3F3F|rcsb pdb:3F3G|rcsb pdb:3F3P|rcsb pdb:4XMM|rcsb pdb:4XMN|rcsb pdb:6X08|refseq:NP_012576.1|sgd:S000003803|mint:P46673|dip:DIP-5818N psi-mi:"MI:0469"(intact) crc64:59399D86BB553030 crc64:4C0A4AD3DB57A023 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IUF7IKaLKMDpFCcuLTjLBB7rD9U559292 rogid:XmACeptHS3SlfgccMUpRYxEA3sI559292 intact-crc:7C94A3A121D9ACE4|rigid:vdhbNead91WUk55cPRGfRAlccwM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P49775 uniprotkb:P49775 intact:EBI-8423|uniprotkb:Q6TQU2|uniprotkb:Q6TQU3|uniprotkb:D6VST4 intact:EBI-8423|uniprotkb:Q6TQU2|uniprotkb:Q6TQU3|uniprotkb:D6VST4 psi-mi:hnt2_yeast(display_long)|uniprotkb:HNT2(gene name)|psi-mi:HNT2(display_short)|uniprotkb:YDR305C(locus name)|uniprotkb:D9740.15(orf name)|uniprotkb:APH1(gene name synonym)|uniprotkb:Diadenosine 5',5'''-P1,P3-triphosphate hydrolase(gene name synonym)|uniprotkb:Dinucleosidetriphosphatase(gene name synonym)|uniprotkb:AP3A hydrolase(gene name synonym)|uniprotkb:Hit family protein 2(gene name synonym) psi-mi:hnt2_yeast(display_long)|uniprotkb:HNT2(gene name)|psi-mi:HNT2(display_short)|uniprotkb:YDR305C(locus name)|uniprotkb:D9740.15(orf name)|uniprotkb:APH1(gene name synonym)|uniprotkb:Diadenosine 5',5'''-P1,P3-triphosphate hydrolase(gene name synonym)|uniprotkb:Dinucleosidetriphosphatase(gene name synonym)|uniprotkb:AP3A hydrolase(gene name synonym)|uniprotkb:Hit family protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335038|imex:IM-14275-1919 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002713|refseq:NP_010591.1|dip:DIP-4620N|mint:P49775|go:"GO:0000166"(nucleotide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0009164"(nucleoside catabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0047710"("bis(5'-adenosyl)-triphosphatase activity")|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR001310("Histidine triad (HIT) protein")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|interpro:IPR039383 sgd:S000002713|refseq:NP_010591.1|dip:DIP-4620N|mint:P49775|go:"GO:0000166"(nucleotide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0009164"(nucleoside catabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0047710"("bis(5'-adenosyl)-triphosphatase activity")|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR001310("Histidine triad (HIT) protein")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|interpro:IPR039383 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:KK/aqRgXTNNl7bNLOQU4H+ZYPOo559292 rogid:KK/aqRgXTNNl7bNLOQU4H+ZYPOo559292 intact-crc:27F7B520320DB872|rigid:TR7ChOecaT7CdIG6Z8+MV4YEvyc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33298 uniprotkb:P50086 intact:EBI-13905|ensemblfungi:YDR394W|uniprotkb:D6VT28 intact:EBI-14028|ensemblfungi:YGR232W|uniprotkb:D6VV12 psi-mi:prs6b_yeast(display_long)|uniprotkb:RPT3(gene name)|psi-mi:RPT3(display_short)|uniprotkb:YNT1(gene name synonym)|uniprotkb:YTA2(gene name synonym)|uniprotkb:YDR394W(locus name)|uniprotkb:D9509.14(orf name)|uniprotkb:Protein YNT1(gene name synonym)|uniprotkb:Tat-binding homolog 2(gene name synonym) psi-mi:psd10_yeast(display_long)|uniprotkb:NAS6(gene name)|psi-mi:NAS6(display_short)|uniprotkb:YGR232W(locus name)|uniprotkb:G8564(orf name)|uniprotkb:Proteasome non-ATPase subunit 6(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335049|imex:IM-14275-1920 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002802|ensemblfungi:YDR394W(gene)|ensemblfungi:YDR394W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|refseq:NP_010682.3|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|rcsb pdb:2DZN|rcsb pdb:2DZO|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33298|dip:DIP-1587N|interpro:IPR003960(AAA ATPase, conserved site) ensemblfungi:YGR232W(gene)|ensemblfungi:YGR232W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0070682"(proteasome regulatory particle assembly)|go:"GO:1904855"(proteasome regulatory particle binding)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|rcsb pdb:1IXV|rcsb pdb:1WG0|rcsb pdb:2DZN|rcsb pdb:2DZO|reactome:R-SCE-8948751|sgd:S000003464|refseq:NP_011748.3|mint:P50086|dip:DIP-1591N psi-mi:"MI:0469"(intact) crc64:E12F0995A60732BD crc64:6B30C0DD034A6289 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:teaQwAlS0ruTNKbLkX7kP4lkn7o559292 rogid:NaPb5AaHRJ7n1VSLw53EIq4YxuY559292 intact-crc:6FA723A325226251|rigid:aRaMbmdi0IIXrQOu0zS8kAON3PY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29366 uniprotkb:P50090 intact:EBI-3508|uniprotkb:D6VQJ6|ensemblfungi:YBR200W intact:EBI-9630|ensemblfungi:YGR238C|uniprotkb:D6VV18 psi-mi:bem1_yeast(display_long)|uniprotkb:Suppressor of RHO3 protein 1(gene name synonym)|uniprotkb:BEM1(gene name)|psi-mi:BEM1(display_short)|uniprotkb:SRO1(gene name synonym)|uniprotkb:YBR200W(locus name)|uniprotkb:YBR1412(orf name) psi-mi:kel2_yeast(display_long)|uniprotkb:KEL2(gene name)|psi-mi:KEL2(display_short)|uniprotkb:G8585(orf name)|uniprotkb:YGR238C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335060|imex:IM-14275-1921 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000404|refseq:NP_009759.3|dip:DIP-688N|mint:P29366|ensemblfungi:YBR200W(gene)|ensemblfungi:YBR200W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030427"(site of polarized growth)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR030507|interpro:IPR035548|interpro:IPR035549|interpro:IPR035550|interpro:IPR036028|interpro:IPR036871|rcsb pdb:1IP9|rcsb pdb:1IPG|rcsb pdb:2CZO|rcsb pdb:2KFK|rcsb pdb:2RQV|rcsb pdb:2RQW|rcsb pdb:2V6V|reactome:R-SCE-5668599 go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090337"(regulation of formin-nucleated actin cable assembly)|go:"GO:1990615"(Kelch-containing formin regulatory complex)|interpro:IPR015915(Kelch-type beta propeller)|ensemblfungi:YGR238C(gene)|ensemblfungi:YGR238C_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0008360"(regulation of cell shape)|refseq:NP_011754.3|sgd:S000003470|dip:DIP-4229N|mint:P50090 psi-mi:"MI:0469"(intact) crc64:FB6C525AE9A19181 crc64:63B9772FF017E6D9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Fq7WxTviE31ivPWGJoZO5DsUcdg559292 rogid:lSnioafH7gyCBHbl539AXlWBAxE559292 intact-crc:83199A67E03AF18E|rigid:yJ+7W5BhmFLClggmNWjZRy8GS20 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38853 uniprotkb:P50090 intact:EBI-9619|ensemblfungi:YHR158C|uniprotkb:D3DLA7|uniprotkb:E9P8X4 intact:EBI-9630|ensemblfungi:YGR238C|uniprotkb:D6VV18 psi-mi:kel1_yeast(display_long)|uniprotkb:KEL1(gene name)|psi-mi:KEL1(display_short)|uniprotkb:YHR158C(locus name) psi-mi:kel2_yeast(display_long)|uniprotkb:KEL2(gene name)|psi-mi:KEL2(display_short)|uniprotkb:G8585(orf name)|uniprotkb:YGR238C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335071|imex:IM-14275-1922 author score:96.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR158C(gene)|ensemblfungi:YHR158C_mRNA(transcript)|go:"GO:0000755"(cytogamy)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090337"(regulation of formin-nucleated actin cable assembly)|go:"GO:1990615"(Kelch-containing formin regulatory complex)|interpro:IPR015915(Kelch-type beta propeller)|refseq:NP_012028.1|sgd:S000001201|dip:DIP-1403N|mint:P38853 go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090337"(regulation of formin-nucleated actin cable assembly)|go:"GO:1990615"(Kelch-containing formin regulatory complex)|interpro:IPR015915(Kelch-type beta propeller)|ensemblfungi:YGR238C(gene)|ensemblfungi:YGR238C_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0008360"(regulation of cell shape)|refseq:NP_011754.3|sgd:S000003470|dip:DIP-4229N|mint:P50090 psi-mi:"MI:0469"(intact) crc64:43D0FC570F1D5E4D crc64:63B9772FF017E6D9 figure legend:tables S3 and S4|author-confidence:96.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pdHtsxpdf1r7G2K9e9EPHajJS3w559292 rogid:lSnioafH7gyCBHbl539AXlWBAxE559292 intact-crc:D1B1F78FCDDAAA93|rigid:j3fxfssltKjMoDuiB8X1j+KatoQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50094 uniprotkb:P38902 intact:EBI-9195|ensemblfungi:YML056C|uniprotkb:Q2VQW8|uniprotkb:D6VZB8 intact:EBI-15806|ensemblfungi:YOL005C|uniprotkb:D6W262 psi-mi:imdh4_yeast(display_long)|uniprotkb:IMD4(gene name)|psi-mi:IMD4(display_short)|uniprotkb:YM9958.06C(orf name)|uniprotkb:YML056C(locus name) psi-mi:rpb11_yeast(display_long)|uniprotkb:YOL005C(locus name)|uniprotkb:RPB11(gene name)|psi-mi:RPB11(display_short)|uniprotkb:DNA-directed RNA polymerase II 13.6 kDa polypeptide(gene name synonym)|uniprotkb:B13.6(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335082|imex:IM-14275-1923 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML056C(gene)|ensemblfungi:YML056C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|reactome:R-SCE-6798695|reactome:R-SCE-73817|refseq:NP_013656.1|sgd:S000004520|dip:DIP-6458N|mint:P50094 refseq:NP_014638.1|sgd:S000005365|ensemblfungi:YOL005C_mRNA(transcript)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR036603|interpro:IPR037685|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|ensemblfungi:YOL005C(gene)|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:4A93|rcsb pdb:5SVA|rcsb pdb:4BBR|rcsb pdb:5U5Q|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4V1M|rcsb pdb:6BLP|rcsb pdb:6UQ3|rcsb pdb:6BM2|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:7KEF|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|dip:DIP-937N|mint:P38902 psi-mi:"MI:0469"(intact) crc64:A73D1E4EFE8AEAD9 crc64:A98D109C5FF8E356 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:S70ravpil5p+waXS1zst4Ii27dY559292 rogid:C9ofD255l4o5MjuGiqUVPfY4FdQ559292 intact-crc:D25D6FB3F8AE6902|rigid:zkpUussZUdZdFaztW/Msg7HMWig false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50094 uniprotkb:P50094 intact:EBI-9195|ensemblfungi:YML056C|uniprotkb:Q2VQW8|uniprotkb:D6VZB8 intact:EBI-9195|ensemblfungi:YML056C|uniprotkb:Q2VQW8|uniprotkb:D6VZB8 psi-mi:imdh4_yeast(display_long)|uniprotkb:IMD4(gene name)|psi-mi:IMD4(display_short)|uniprotkb:YM9958.06C(orf name)|uniprotkb:YML056C(locus name) psi-mi:imdh4_yeast(display_long)|uniprotkb:IMD4(gene name)|psi-mi:IMD4(display_short)|uniprotkb:YM9958.06C(orf name)|uniprotkb:YML056C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335093|imex:IM-14275-1924 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML056C(gene)|ensemblfungi:YML056C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|reactome:R-SCE-6798695|reactome:R-SCE-73817|refseq:NP_013656.1|sgd:S000004520|dip:DIP-6458N|mint:P50094 ensemblfungi:YML056C(gene)|ensemblfungi:YML056C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|reactome:R-SCE-6798695|reactome:R-SCE-73817|refseq:NP_013656.1|sgd:S000004520|dip:DIP-6458N|mint:P50094 psi-mi:"MI:0469"(intact) crc64:A73D1E4EFE8AEAD9 crc64:A73D1E4EFE8AEAD9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:S70ravpil5p+waXS1zst4Ii27dY559292 rogid:S70ravpil5p+waXS1zst4Ii27dY559292 intact-crc:361A832B0EA1CA1F|rigid:kg1rrGnNmC0E8fR9PhfBx/7Lqcw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50094 uniprotkb:P50095 intact:EBI-9195|ensemblfungi:YML056C|uniprotkb:Q2VQW8|uniprotkb:D6VZB8 intact:EBI-9190|ensemblfungi:YLR432W|uniprotkb:D6VZ67 psi-mi:imdh4_yeast(display_long)|uniprotkb:IMD4(gene name)|psi-mi:IMD4(display_short)|uniprotkb:YM9958.06C(orf name)|uniprotkb:YML056C(locus name) psi-mi:imdh3_yeast(display_long)|uniprotkb:IMD3(gene name)|psi-mi:IMD3(display_short)|uniprotkb:L9753.4(orf name)|uniprotkb:YLR432W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335104|imex:IM-14275-1925 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML056C(gene)|ensemblfungi:YML056C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|reactome:R-SCE-6798695|reactome:R-SCE-73817|refseq:NP_013656.1|sgd:S000004520|dip:DIP-6458N|mint:P50094 ensemblfungi:YLR432W(gene)|ensemblfungi:YLR432W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|reactome:R-SCE-6798695|reactome:R-SCE-73817|refseq:NP_013536.3|sgd:S000004424|dip:DIP-1947N|mint:P50095 psi-mi:"MI:0469"(intact) crc64:A73D1E4EFE8AEAD9 crc64:A0C84C22527AAEA6 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:S70ravpil5p+waXS1zst4Ii27dY559292 rogid:UUEyn+zhL8Z1aasK3r/inGhtO1c559292 intact-crc:A9A3880D2B55944B|rigid:gwC+jW4uS2Uppr5O3GHhTj871WM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50094 uniprotkb:P50095 intact:EBI-9195|ensemblfungi:YML056C|uniprotkb:Q2VQW8|uniprotkb:D6VZB8 intact:EBI-9190|ensemblfungi:YLR432W|uniprotkb:D6VZ67 psi-mi:imdh4_yeast(display_long)|uniprotkb:IMD4(gene name)|psi-mi:IMD4(display_short)|uniprotkb:YM9958.06C(orf name)|uniprotkb:YML056C(locus name) psi-mi:imdh3_yeast(display_long)|uniprotkb:IMD3(gene name)|psi-mi:IMD3(display_short)|uniprotkb:L9753.4(orf name)|uniprotkb:YLR432W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335115|imex:IM-14275-1926 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML056C(gene)|ensemblfungi:YML056C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|reactome:R-SCE-6798695|reactome:R-SCE-73817|refseq:NP_013656.1|sgd:S000004520|dip:DIP-6458N|mint:P50094 ensemblfungi:YLR432W(gene)|ensemblfungi:YLR432W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|reactome:R-SCE-6798695|reactome:R-SCE-73817|refseq:NP_013536.3|sgd:S000004424|dip:DIP-1947N|mint:P50095 psi-mi:"MI:0469"(intact) crc64:A73D1E4EFE8AEAD9 crc64:A0C84C22527AAEA6 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:S70ravpil5p+waXS1zst4Ii27dY559292 rogid:UUEyn+zhL8Z1aasK3r/inGhtO1c559292 intact-crc:286272353538A0C5|rigid:gwC+jW4uS2Uppr5O3GHhTj871WM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50095 uniprotkb:P50095 intact:EBI-9190|ensemblfungi:YLR432W|uniprotkb:D6VZ67 intact:EBI-9190|ensemblfungi:YLR432W|uniprotkb:D6VZ67 psi-mi:imdh3_yeast(display_long)|uniprotkb:IMD3(gene name)|psi-mi:IMD3(display_short)|uniprotkb:L9753.4(orf name)|uniprotkb:YLR432W(locus name) psi-mi:imdh3_yeast(display_long)|uniprotkb:IMD3(gene name)|psi-mi:IMD3(display_short)|uniprotkb:L9753.4(orf name)|uniprotkb:YLR432W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335126|imex:IM-14275-1927 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR432W(gene)|ensemblfungi:YLR432W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|reactome:R-SCE-6798695|reactome:R-SCE-73817|refseq:NP_013536.3|sgd:S000004424|dip:DIP-1947N|mint:P50095 ensemblfungi:YLR432W(gene)|ensemblfungi:YLR432W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|reactome:R-SCE-6798695|reactome:R-SCE-73817|refseq:NP_013536.3|sgd:S000004424|dip:DIP-1947N|mint:P50095 psi-mi:"MI:0469"(intact) crc64:A0C84C22527AAEA6 crc64:A0C84C22527AAEA6 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UUEyn+zhL8Z1aasK3r/inGhtO1c559292 rogid:UUEyn+zhL8Z1aasK3r/inGhtO1c559292 intact-crc:A8A38809962C0C09|rigid:0uBhaESoc+BnQCiZDKffkzcK2z0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50106 uniprotkb:P50106 intact:EBI-15750|uniprotkb:D6VSD7|ensemblfungi:YDR156W intact:EBI-15750|uniprotkb:D6VSD7|ensemblfungi:YDR156W psi-mi:rpa14_yeast(display_long)|uniprotkb:RPA14(gene name)|psi-mi:RPA14(display_short)|uniprotkb:YDR156W(locus name)|uniprotkb:YD8358.11(orf name)|uniprotkb:DNA-directed RNA polymerase I 14 kDa polypeptide(gene name synonym) psi-mi:rpa14_yeast(display_long)|uniprotkb:RPA14(gene name)|psi-mi:RPA14(display_short)|uniprotkb:YDR156W(locus name)|uniprotkb:YD8358.11(orf name)|uniprotkb:DNA-directed RNA polymerase I 14 kDa polypeptide(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335137|imex:IM-14275-1928 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010440.1|sgd:S000002563|ensemblfungi:YDR156W(gene)|ensemblfungi:YDR156W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0008361"(regulation of cell size)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR013239(RNA polymerase I, subunit RPA14, fungi)|rcsb pdb:2RF4|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:6RWE|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6TPS|dip:DIP-2053N|mint:P50106 refseq:NP_010440.1|sgd:S000002563|ensemblfungi:YDR156W(gene)|ensemblfungi:YDR156W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0008361"(regulation of cell size)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR013239(RNA polymerase I, subunit RPA14, fungi)|rcsb pdb:2RF4|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:6RWE|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6TPS|dip:DIP-2053N|mint:P50106 psi-mi:"MI:0469"(intact) crc64:D2318636ABDE68B9 crc64:D2318636ABDE68B9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fIDAOOpJrLwSXy7vygwP4Cu96Ww559292 rogid:fIDAOOpJrLwSXy7vygwP4Cu96Ww559292 intact-crc:E51DDA8502C43D49|rigid:MKfKWKNBs0jwbHaWSw2b6mBCX0E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06634 uniprotkb:P50109 intact:EBI-5744|uniprotkb:D6W2R0|ensemblfungi:YOR204W intact:EBI-14050|uniprotkb:Q07170|uniprotkb:Q870H3|ensemblfungi:YML017W|uniprotkb:D6VZF7 psi-mi:ded1_yeast(display_long)|uniprotkb:DED1(gene name)|psi-mi:DED1(display_short)|uniprotkb:SPP81(gene name synonym)|uniprotkb:YOR204W(locus name)|uniprotkb:DEAD box protein 1(gene name synonym) psi-mi:psp2_yeast(display_long)|uniprotkb:PSP2(gene name)|psi-mi:PSP2(display_short)|uniprotkb:YML017W(locus name)|uniprotkb:YM9571.01(orf name)|uniprotkb:Polymerase suppressor protein 2(gene name synonym)|uniprotkb:Mitochondrial regulator of splicing 15(gene name synonym)|uniprotkb:MRS15(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335148|imex:IM-14275-1929 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005730|refseq:NP_014847.3|dip:DIP-5820N|mint:P06634|ensemblfungi:YOR204W(gene)|ensemblfungi:YOR204W_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763|reactome:R-SCE-6798695 sgd:S000004479|refseq:NP_013695.2|ensemblfungi:YML017W(gene)|ensemblfungi:YML017W_mRNA(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0000932"(P-body)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|reactome:R-SCE-6791226|go:"GO:0003723"(RNA binding)|mint:P50109 psi-mi:"MI:0469"(intact) crc64:B6722D94C03BFA4B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FkldumX6m5gBuuaG09aTJ0kuMZM559292 rogid:IW+vaICiPBsINLxQCo1dNXRX5Lw559292 intact-crc:4158096358EDF317|rigid:L9FVBJ8LVUasizWSND4jXcZ+S8U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50273 uniprotkb:Q8TGJ2 intact:EBI-19035|uniprotkb:D6VSY0|ensemblfungi:YDR350C intact:EBI-2047109|uniprotkb:D6W1Q1|ensemblfungi:YNR075C-A psi-mi:atp22_yeast(display_long)|uniprotkb:ATP22(gene name)|psi-mi:ATP22(display_short)|uniprotkb:YDR350C(locus name)|uniprotkb:D9476.9(orf name)|uniprotkb:TCM10(gene name synonym) psi-mi:yn075_yeast(display_long)|uniprotkb:YNR075C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335159|imex:IM-14275-1930 author score:97.40 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002758|ensemblfungi:YDR350C(gene)|ensemblfungi:YDR350C_mRNA(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0045182"(translation regulator activity)|go:"GO:0070071"(proton-transporting two-sector ATPase complex assembly)|go:"GO:0070131"(positive regulation of mitochondrial translation)|interpro:IPR017207(Mitochondrial ATPase subunit 6-specific translation factor Atp22)|refseq:NP_010637.4|dip:DIP-5246N|mint:P50273 sgd:S000028706|refseq:NP_878159.3|mint:Q8TGJ2|ensemblfungi:YNR075C-A(gene)|ensemblfungi:YNR075C-A_mRNA(transcript) psi-mi:"MI:0469"(intact) crc64:A88992848F8F49A4 - figure legend:tables S3 and S4|author-confidence:97.40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:gtXiP1dqs4FI3TaGDUzewbvljMA559292 rogid:a2YkRms9fcm6XZTy1Q74gRGCXPY559292 intact-crc:E289AA0A36C32628|rigid:I3NBGkdFHdQt7MKOEVSzIdgxCq8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10823 uniprotkb:P50276 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335170|imex:IM-14275-1931 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) crc64:881B91792AE91748 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:3F107DEC36FEF69D|rigid:/j3yZZ5fatWA4/EbJDgh+GjaXWc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P19807 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335181|imex:IM-14275-1932 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:17DBE997CA6245F3|rigid:PTskKeFnTkio9Ud2cYIr3d5DsZM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P23585 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-2054100|uniprotkb:D6VZI5|ensemblfungi:YMR011W psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:hxt2_yeast(display_long)|uniprotkb:YM8270.15(orf name)|uniprotkb:YMR011W(locus name)|uniprotkb:HXT2(gene name)|psi-mi:HXT2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335192|imex:IM-14275-1933 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_013724.1|sgd:S000004613|dip:DIP-7912N|mint:P23585|ensemblfungi:YMR011W(gene)|ensemblfungi:YMR011W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:d4PFyh6BHnB/WnnF3A4GF3EphgY559292 intact-crc:B836A2653649367A|rigid:ZwUnu4KICkoXPqpbFaAbLyo/NRg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P26570 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335203|imex:IM-14275-1934 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N psi-mi:"MI:0469"(intact) - crc64:8B7F009521F72C15 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 intact-crc:D01CF096440F7973|rigid:VMhvsWB2f3dYYRjfPY2kyoGn09o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30605 uniprotkb:P50276 intact:EBI-2050956|uniprotkb:D6VTB9|ensemblfungi:YDR497C intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:itr1_yeast(display_long)|uniprotkb:D9719.3(orf name)|uniprotkb:YDR497C(locus name)|uniprotkb:ITR1(gene name)|psi-mi:ITR1(display_short) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335214|imex:IM-14275-1935 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010785.1|sgd:S000002905|dip:DIP-7406N|mint:P30605|ensemblfungi:YDR497C(gene)|ensemblfungi:YDR497C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GgtK4YFe7ZCZcmVpV5q1KY2F0Ds559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:69B1CE2972AF30F1|rigid:S8MDiazYxek/vGzBO4PVFOL+3WQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:P50276 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335225|imex:IM-14275-1936 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:0CD4D2EB69295629|rigid:1ngez3YPPHHFVs/eupCL8CvIc8Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P32487 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-10258|uniprotkb:D6W0S6|ensemblfungi:YNL268W psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:lyp1_yeast(display_long)|uniprotkb:LYP1(gene name)|psi-mi:LYP1(display_short)|uniprotkb:N0790(orf name)|uniprotkb:YNL268W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335236|imex:IM-14275-1937 author score:99.34 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region)|refseq:NP_014131.1|sgd:S000005212|ensemblfungi:YNL268W(gene)|ensemblfungi:YNL268W_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005739"(mitochondrion)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015174"(basic amino acid transmembrane transporter activity)|go:"GO:0015802"(basic amino acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032126"(eisosome)|mint:P32487 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.34|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:54NWGujHb25P5sWLEHSOC6ytuG4559292 intact-crc:C69C10322DBEBF3E|rigid:x/pU92gDtE9K01LuIlo+fEjr9Vo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P33302 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-13038|uniprotkb:D6W2L0|ensemblfungi:YOR153W psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:pdr5_yeast(display_long)|uniprotkb:PDR5(gene name)|psi-mi:PDR5(display_short)|uniprotkb:LEM1(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 5(gene name synonym)|uniprotkb:Suppressor of toxicity of sporidesmin(gene name synonym)|uniprotkb:YOR153W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335247|imex:IM-14275-1938 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N sgd:S000005679|refseq:NP_014796.3|mint:P33302|dip:DIP-6776N|ensemblfungi:YOR153W(gene)|ensemblfungi:YOR153W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR029481|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:Sd6SJWf6B0rDZnLVaPHyvr4lhew559292 intact-crc:2DE01A9540D5BC67|rigid:ik3Xp3i0aVusXX1ygg5cgPFJdC8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P33413 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-2060312|uniprotkb:D3DKP5|ensemblfungi:YHL016C psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:dur3_yeast(display_long)|uniprotkb:DUR3(gene name)|psi-mi:DUR3(display_short)|uniprotkb:YHL016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335258|imex:IM-14275-1939 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N interpro:IPR031155|refseq:NP_011847.1|sgd:S000001008|interpro:IPR001734(Na+/solute symporter)|interpro:IPR038377|mint:P33413|ensemblfungi:YHL016C(gene)|ensemblfungi:YHL016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0015204"(urea transmembrane transporter activity)|go:"GO:0015489"(putrescine transmembrane transporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015840"(urea transport)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:oTFsdtOngA3q5wCbhK/fpVlIsz0559292 intact-crc:FB0D3D91F90E6FD1|rigid:6UpVUaRbRYDGBEa+Oh0RSSJpJV8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P50276 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335269|imex:IM-14275-1940 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:DCF8FDCC7F6C1168|rigid:JszBnD/iu/frW+6cO/sj0qAH1Qs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P36027 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335280|imex:IM-14275-1941 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:DF16EB66013D67DF|rigid:BkMCgCVQO+3ro0/NjPY6GZf+6fc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P38143 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-7863|uniprotkb:D6VQP0|ensemblfungi:YBR244W psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:gpx2_yeast(display_long)|uniprotkb:GPX2(gene name)|psi-mi:GPX2(display_short)|uniprotkb:Glutathione peroxidase homolog 2(gene name synonym)|uniprotkb:YBR1632(orf name)|uniprotkb:YBR244W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335291|imex:IM-14275-1942 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N sgd:S000000448|refseq:NP_009803.3|mint:P38143|dip:DIP-8180N|ensemblfungi:YBR244W(gene)|ensemblfungi:YBR244W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR029759|interpro:IPR029760|interpro:IPR036249|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:cL8rm6IttRi0QYzWVEooubWkZN8559292 intact-crc:654E923AEF50909B|rigid:XuJIdQXXalN3G4aZFmHKUcCthyA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P38196 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-7158|uniprotkb:D6VPV6|ensemblfungi:YBL042C psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:fui1_yeast(display_long)|uniprotkb:FUI1(gene name)|psi-mi:FUI1(display_short)|uniprotkb:YBL0406(orf name)|uniprotkb:YBL042C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335302|imex:IM-14275-1943 author score:99.37 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_009511.1|sgd:S000000138|dip:DIP-1321N|mint:P38196|ensemblfungi:YBL042C(gene)|ensemblfungi:YBL042C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015205"(nucleobase transmembrane transporter activity)|go:"GO:0015213"(uridine transmembrane transporter activity)|go:"GO:0015851"(nucleobase transport)|go:"GO:0015862"(uridine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR001248(Permease for cytosine/purines, uracil, thiamine, allantoin)|interpro:IPR012681(Nucleobase cation symporter-1, NCS1) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.37|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:ESbe5XfGhfMFQk2sgjqm+duIHyg559292 intact-crc:19A780FC946C3AEA|rigid:2HGjV19K+Gkl+avmVOgmReV7Cjw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38234 uniprotkb:P50276 intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335313|imex:IM-14275-1944 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:3D583125C203F216|rigid:wkd9MuobTK4Ft9UCvH5gQEl5rZk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P39719 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-20703|uniprotkb:Q05165|uniprotkb:D6VPG5|ensemblfungi:YAL053W psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:flc2_yeast(display_long)|uniprotkb:YAL053W(locus name)|uniprotkb:FLC2(gene name)|psi-mi:FLC2(display_short)|uniprotkb:FAD transporter 2(gene name synonym)|uniprotkb:TRP-like ion channel FLC2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335324|imex:IM-14275-1945 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_009348.2|sgd:S000000049|ensemblfungi:YAL053W(gene)|ensemblfungi:YAL053W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241|go:"GO:0055085"(transmembrane transport)|dip:DIP-6708N|mint:P39719 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:NOmMW54DNa0o7vM945DlZgVUy44559292 intact-crc:36363B77683C765E|rigid:xsp/i1FxRvcK9MCNtYrzCmWR3A8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P40260 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-10714|ensemblfungi:YGR121C|uniprotkb:D6VUQ2 psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:mep1_yeast(display_long)|uniprotkb:MEP1(gene name)|psi-mi:MEP1(display_short)|uniprotkb:YGR121C(locus name)|uniprotkb:G6331(orf name)|uniprotkb:AMT1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335335|imex:IM-14275-1946 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N ensemblfungi:YGR121C(gene)|ensemblfungi:YGR121C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|sgd:S000003353|refseq:NP_011636.3|mint:P40260|dip:DIP-5530N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:VnoBl5jhQD24N0SbCLv68HCwl1U559292 intact-crc:CA7BB2B306AD2913|rigid:f80CRwYzlrNS0xStw8ukk/UYmWI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40474 uniprotkb:P50276 intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335346|imex:IM-14275-1947 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:D779F4A1F7EDBE96|rigid:QOrk4e6Nys2HxhkenV+5bymm4SI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40485 uniprotkb:P50276 intact:EBI-25172|uniprotkb:D6VVI2|ensemblfungi:YIL105C intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:slm1_yeast(display_long)|uniprotkb:TORC2 effector protein SLM1(gene name synonym)|uniprotkb:Synthetic lethal with MSS4 protein 1(gene name synonym)|uniprotkb:YIL105C(locus name)|uniprotkb:SLM1(gene name)|psi-mi:SLM1(display_short)|uniprotkb:LIT2(gene name synonym) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335357|imex:IM-14275-1948 author score:99.37 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012161.1|sgd:S000001367|mint:P40485|dip:DIP-1353N|ensemblfungi:YIL105C(gene)|ensemblfungi:YIL105C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070941"(eisosome assembly)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR033191|interpro:IPR043453|rcsb pdb:3NSU|rcsb pdb:4A5K|rcsb pdb:4A6F|rcsb pdb:4A6H|rcsb pdb:4A6K ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) crc64:849C82CC0960014B - figure legend:tables S3 and S4|author-confidence:99.37|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:f0Gtntpff7Oav37jlVaggG2VI30559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:7152E675704D86DF|rigid:NVw19uGZ0CE/caTdFE4BjmZG/BE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P50276 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335368|imex:IM-14275-1949 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:DD66B67FF268358D|rigid:F1y0DSCUC1Z9PGHzdgLgz39fEOk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53049 uniprotkb:P50276 intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335379|imex:IM-14275-1950 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:F3025933933861E0|rigid:Lj9+o6A59B+dw2RxiGgaEUtBdM4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P53139 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-23908|uniprotkb:D6VU38|ensemblfungi:YGL108C psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:ygk8_yeast(display_long)|uniprotkb:G3070(orf name)|uniprotkb:YGL108C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335390|imex:IM-14275-1951 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N sgd:S000003076|refseq:NP_011407.3|mint:P53139|ensemblfungi:YGL108C(gene)|ensemblfungi:YGL108C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:6rg2zcMN57peeKKy/RolIDcNaLc559292 intact-crc:6ACA5ADB6AE7898F|rigid:m+z+J7Pi/5tqM3gXoU4NUgEW1O8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P53278 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335401|imex:IM-14275-1952 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome) psi-mi:"MI:0469"(intact) - crc64:D482327C9274C026 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292 intact-crc:01F9267ACAEE68BE|rigid:07qe+C99fTxzEVNXyDbX6XWlWmU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53283 uniprotkb:P50276 intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335412|imex:IM-14275-1953 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:F09985494886178D|rigid:6tzNq2Ui8vhidQ2zGGPhgrv0Tf0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P53388 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335423|imex:IM-14275-1954 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) psi-mi:"MI:0469"(intact) - crc64:488A382656039D0B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 intact-crc:72CB9EAB021E2223|rigid:3RwxhaITToA059RVH8Jb8BvcvHo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P53390 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335434|imex:IM-14275-1955 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N psi-mi:"MI:0469"(intact) - crc64:2309338F36D96258 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 intact-crc:EE5C7E910B9924DA|rigid:/JcYyA91GpwGyCnu5u/SHuegZqA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P53832 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-2055941|uniprotkb:D6W0R1|ensemblfungi:YNL283C psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:wsc2_yeast(display_long)|uniprotkb:YNL283C(locus name)|uniprotkb:N0583(orf name)|uniprotkb:WSC2(gene name)|psi-mi:WSC2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335445|imex:IM-14275-1956 author score:99.34 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_014116.1|sgd:S000005227|interpro:IPR002889(Carbohydrate-binding WSC)|mint:P53832|ensemblfungi:YNL283C(gene)|ensemblfungi:YNL283C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.34|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:5wadvTv6SxcIAb60yfnuGMfa8pY559292 intact-crc:72130D41794E9383|rigid:jil0n1FWeFMb42cc91cwdMVcn8Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:Q02785 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335456|imex:IM-14275-1957 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:B96462347A08D8C2|rigid:PXWO69nlR6qZHJjmhzHQ3m984L8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:Q03640 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335467|imex:IM-14275-1958 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) - crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:F7546719D3B88F9F|rigid:CrMcaWTXBMndAb2UXsp2JdZ8enc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:Q05812 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-33150|uniprotkb:Q7LIF4|uniprotkb:D6VYL9|ensemblfungi:YLR219W psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:msc3_yeast(display_long)|uniprotkb:MSC3(gene name)|psi-mi:MSC3(display_short)|uniprotkb:YLR219W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335478|imex:IM-14275-1959 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N sgd:S000004209|refseq:NP_013320.1|mint:Q05812|dip:DIP-6321N|ensemblfungi:YLR219W(gene)|ensemblfungi:YLR219W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007131"(reciprocal meiotic recombination) psi-mi:"MI:0469"(intact) - crc64:1962D638DB602B71 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:xS8zCG9eHY8V0vNstOwUuTcI3Ao559292 intact-crc:74E9F7EDD33D3156|rigid:VPlquJ5uawrRbXTwq2Y2yQ7rE8M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:Q06170 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-35994|uniprotkb:D6VYW8|ensemblfungi:YLR326W psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:yl326_yeast(display_long)|uniprotkb:YLR326W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335489|imex:IM-14275-1960 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_013430.1|sgd:S000004318|mint:Q06170|dip:DIP-3995N|ensemblfungi:YLR326W(gene)|ensemblfungi:YLR326W_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR025187 psi-mi:"MI:0469"(intact) - crc64:724CD7833AA9B416 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:Ufkoj1kRp4Y9JTsgbL+3k8hzJyo559292 intact-crc:9940260AD503D402|rigid:3sls3Szj7GC+S/Hue2g8kTk44A0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06451 uniprotkb:P50276 intact:EBI-34275|uniprotkb:D6W4F2|ensemblfungi:YPR156C intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:tpo3_yeast(display_long)|uniprotkb:TPO3(gene name)|psi-mi:TPO3(display_short)|uniprotkb:P9584.7(orf name)|uniprotkb:YPR156C(locus name) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335500|imex:IM-14275-1961 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015482.1|sgd:S000006360|mint:Q06451|dip:DIP-3907N|ensemblfungi:YPR156C(gene)|ensemblfungi:YPR156C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) crc64:D260ED161F800502 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oVpx7Bjk/mK2Q7+/j05tX3gHw7k559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:D6527E679B02D0CF|rigid:s8GjClaSAIc5tYtCJH2YDcsalpA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:Q06689 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-38659|uniprotkb:D6VZ50|ensemblfungi:YLR413W psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:yl413_yeast(display_long)|uniprotkb:YLR413W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335511|imex:IM-14275-1962 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_013517.1|sgd:S000004405|mint:Q06689|dip:DIP-5075N|ensemblfungi:YLR413W(gene)|ensemblfungi:YLR413W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0071944"(cell periphery)|interpro:IPR009571(SUR7) psi-mi:"MI:0469"(intact) - crc64:92E23436DC857E95 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:AoTGKjLhw0NECrtuftZqLANonds559292 intact-crc:2BE40D5A2D71EE55|rigid:/SiNxj7LB17Bd/IwuzsVUeO5E08 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:Q07651 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335522|imex:IM-14275-1963 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:B74F904A3445BD02|rigid:tK3jVBHfC17QHGDPUazWnNIhqf0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07824 uniprotkb:P50276 intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335533|imex:IM-14275-1964 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:49E1A49B177CA405|rigid:MsMWBq11JhsgWbrw58VIrRMENHU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08967 uniprotkb:P50276 intact:EBI-36673|uniprotkb:D6W3E9|ensemblfungi:YPL221W intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:flc1_yeast(display_long)|uniprotkb:FAD transporter 1(gene name synonym)|uniprotkb:FLC1(gene name)|psi-mi:FLC1(display_short)|uniprotkb:TRP-like ion channel protein FLC1(gene name synonym)|uniprotkb:Heme utilization factor 1(gene name synonym)|uniprotkb:Bypass of PAM1 protein 1(gene name synonym)|uniprotkb:HUF1(gene name synonym)|uniprotkb:YPL221W(locus name)|uniprotkb:BOP1(gene name synonym) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335544|imex:IM-14275-1965 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015103.1|sgd:S000006142|mint:Q08967|dip:DIP-3965N|ensemblfungi:YPL221W(gene)|ensemblfungi:YPL221W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055085"(transmembrane transport)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241 ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:r6CcZGEjxHUk2w0iBUBvnAPaFd4559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:00C33E070DB971A3|rigid:Ri3C/0zNefygONgDkA+Vr+swPIw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12256 uniprotkb:P50276 intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335555|imex:IM-14275-1966 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:4488742CE38E04E9|rigid:p+Z3JtzzwDtY8RItStI0P1m9/S0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:Q12335 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335566|imex:IM-14275-1967 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) - crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:BCD3A0C55268FA25|rigid:yu62QLsFCvdH20ASHVqinkhSUYg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:Q3E756 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-2044812|uniprotkb:D6VPX0|ensemblfungi:YBL029C-A psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:yb029_yeast(display_long)|uniprotkb:YBL029C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335577|imex:IM-14275-1968 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N sgd:S000007591|refseq:NP_076874.1|mint:Q3E756|ensemblfungi:YBL029C-A(gene)|ensemblfungi:YBL029C-A_mRNA(transcript)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:Y9LDkESr65DK5SLFNTw1dBKeqPc559292 intact-crc:DF5EDF588608B95B|rigid:ZaxVjzCp6NDRCZ0y6HA3HF/ZY88 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50278 uniprotkb:P38009 intact:EBI-17675|uniprotkb:D6W1K9|ensemblfungi:YNR034W intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 psi-mi:sol1_yeast(display_long)|uniprotkb:SOL1(gene name)|psi-mi:SOL1(display_short)|uniprotkb:N3291(orf name)|uniprotkb:YNR034W(locus name) psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335588|imex:IM-14275-1969 author score:97.40 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNR034W(gene)|ensemblfungi:YNR034W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0009051"(pentose-phosphate shunt, oxidative branch)|go:"GO:0017057"(6-phosphogluconolactonase activity)|interpro:IPR005900(6-phosphogluconolactonase)|interpro:IPR006148(Glucosamine/galactosamine-6-phosphate isomerase)|interpro:IPR037171|interpro:IPR039104|sgd:S000005317|refseq:NP_014432.3|dip:DIP-962N|mint:P50278 refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N psi-mi:"MI:0469"(intact) - crc64:8ABA71761B512242 figure legend:tables S3 and S4|author-confidence:97.40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UppPyxeNxc3Wefo2uLdYte0BDfg559292 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 intact-crc:607B963397250E4A|rigid:qR5Tx67aAYBe39mHB0LGFj5Rmtw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50942 uniprotkb:P38328 intact:EBI-28834|uniprotkb:D6W174|ensemblfungi:YNL106C intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C psi-mi:inp52_yeast(display_long)|uniprotkb:YNL106C(locus name)|uniprotkb:N2160(orf name)|uniprotkb:INP52(gene name)|psi-mi:INP52(display_short)|uniprotkb:SJL2(gene name synonym)|uniprotkb:Synaptojanin-like protein 2(gene name synonym) psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335599|imex:IM-14275-1970 author score:99.26 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014293.1|sgd:S000005050|dip:DIP-2764N|mint:P50942|ensemblfungi:YNL106C(gene)|ensemblfungi:YNL106C_mRNA(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR002013(Synaptojanin, N-terminal)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|reactome:R-SCE-1660499|reactome:R-SCE-8856828 sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:97B279870DFE6F65 crc64:D75C6BB8EC35EEDF figure legend:tables S3 and S4|author-confidence:99.26|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:r08JCOgVbZLSAZaMWTAD3Enrkww559292 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 intact-crc:B6AE09F46174B1E0|rigid:r+GZr9gevQ3LeFnpkhspFqXFsxA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50942 uniprotkb:P43603 intact:EBI-28834|uniprotkb:D6W174|ensemblfungi:YNL106C intact:EBI-22980|uniprotkb:D6VTQ4|ensemblfungi:YFR024C-A psi-mi:inp52_yeast(display_long)|uniprotkb:YNL106C(locus name)|uniprotkb:N2160(orf name)|uniprotkb:INP52(gene name)|psi-mi:INP52(display_short)|uniprotkb:SJL2(gene name synonym)|uniprotkb:Synaptojanin-like protein 2(gene name synonym) psi-mi:lsb3_yeast(display_long)|uniprotkb:LSB3(gene name)|psi-mi:LSB3(display_short)|uniprotkb:YFR024C(orf name)|uniprotkb:YFR024C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335610|imex:IM-14275-1971 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014293.1|sgd:S000005050|dip:DIP-2764N|mint:P50942|ensemblfungi:YNL106C(gene)|ensemblfungi:YNL106C_mRNA(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR002013(Synaptojanin, N-terminal)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|reactome:R-SCE-1660499|reactome:R-SCE-8856828 sgd:S000002968|refseq:NP_219497.4|dip:DIP-6259N|mint:P43603|ensemblfungi:YFR024C-A(gene)|ensemblfungi:YFR024C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:1OOT|rcsb pdb:1SSH psi-mi:"MI:0469"(intact) crc64:97B279870DFE6F65 crc64:F486C787B5771AAC figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:r08JCOgVbZLSAZaMWTAD3Enrkww559292 rogid:zKMZQRpG4d/at/NecQDyEi/kVKg559292 intact-crc:B1F83AEB6B7E48AA|rigid:JMLY7/EVSfYpgB+W3S42P4HP4Bw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51862 uniprotkb:P53832 intact:EBI-15702|ensemblfungi:YLR371W intact:EBI-2055941|uniprotkb:D6W0R1|ensemblfungi:YNL283C psi-mi:rom2_yeast(display_long)|uniprotkb:L8039.3(orf name)|uniprotkb:YLR371W(locus name)|uniprotkb:ROM2(gene name)|psi-mi:ROM2(display_short) psi-mi:wsc2_yeast(display_long)|uniprotkb:YNL283C(locus name)|uniprotkb:N0583(orf name)|uniprotkb:WSC2(gene name)|psi-mi:WSC2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335621|imex:IM-14275-1972 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013475.1|sgd:S000004363|ensemblfungi:YLR371W(gene)|ensemblfungi:YLR371W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005934"(cellular bud tip)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0071944"(cell periphery)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001180(Citron-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR036388|interpro:IPR036390|interpro:IPR041675|dip:DIP-4663N|mint:P51862 refseq:NP_014116.1|sgd:S000005227|interpro:IPR002889(Carbohydrate-binding WSC)|mint:P53832|ensemblfungi:YNL283C(gene)|ensemblfungi:YNL283C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip) psi-mi:"MI:0469"(intact) crc64:5FBC542114E7BC92 - figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:luTnaxUia0IpVsc98qi/jtqwJns559292 rogid:5wadvTv6SxcIAb60yfnuGMfa8pY559292 intact-crc:CE2BFF4289891E91|rigid:L2qR0JLvWhDbpo4Cx/Nup97wMNI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51862 uniprotkb:Q07622 intact:EBI-15702|ensemblfungi:YLR371W intact:EBI-38674|uniprotkb:D6VRF1|ensemblfungi:YDL203C psi-mi:rom2_yeast(display_long)|uniprotkb:L8039.3(orf name)|uniprotkb:YLR371W(locus name)|uniprotkb:ROM2(gene name)|psi-mi:ROM2(display_short) psi-mi:ack1_yeast(display_long)|uniprotkb:ACK1(gene name)|psi-mi:ACK1(display_short)|uniprotkb:D1066(orf name)|uniprotkb:YDL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335632|imex:IM-14275-1973 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013475.1|sgd:S000004363|ensemblfungi:YLR371W(gene)|ensemblfungi:YLR371W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005934"(cellular bud tip)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0071944"(cell periphery)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001180(Citron-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR036388|interpro:IPR036390|interpro:IPR041675|dip:DIP-4663N|mint:P51862 refseq:NP_010078.1|sgd:S000002362|mint:Q07622|dip:DIP-1805N|ensemblfungi:YDL203C(gene)|ensemblfungi:YDL203C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical) psi-mi:"MI:0469"(intact) crc64:5FBC542114E7BC92 crc64:5CBB9D907443EC2E figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:luTnaxUia0IpVsc98qi/jtqwJns559292 rogid:go1ERLYKijUuj/M98qnaFXnvuww559292 intact-crc:FD2085B259D71F76|rigid:/b43y/bhYhHHPkHTdc2cVTlp2fY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51979 uniprotkb:P23202 intact:EBI-8296|uniprotkb:D6VV84|ensemblfungi:YGL251C intact:EBI-20138|uniprotkb:D6W0W3|ensemblfungi:YNL229C psi-mi:hfm1_yeast(display_long)|uniprotkb:HFM1(gene name)|psi-mi:HFM1(display_short)|uniprotkb:MER3(gene name synonym)|uniprotkb:YGL251C(locus name)|uniprotkb:NRE1046(orf name)|uniprotkb:Protein HFM1(gene name synonym) psi-mi:ure2_yeast(display_long)|uniprotkb:URE2(gene name)|psi-mi:URE2(display_short)|uniprotkb:Disulfide reductase(gene name synonym)|uniprotkb:Glutathione peroxidase(gene name synonym)|uniprotkb:N1165(orf name)|uniprotkb:YNL229C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335643|imex:IM-14275-1974 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011263.2|sgd:S000003220|mint:P51979|dip:DIP-2604N|ensemblfungi:YGL251C(gene)|ensemblfungi:YGL251C_mRNA(transcript)|go:"GO:0000404"(heteroduplex DNA loop binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990166"(protein localization to site of double-strand break)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR036388 refseq:NP_014170.1|sgd:S000005173|ensemblfungi:YNL229C(gene)|ensemblfungi:YNL229C_mRNA(transcript)|mint:P23202|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0010044"(response to aluminum ion)|go:"GO:0032447"(protein urmylation)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR017298(Prion URE2)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:1G6W|rcsb pdb:1G6Y|rcsb pdb:1HQO|rcsb pdb:1JZR|rcsb pdb:1K0A|rcsb pdb:1K0B|rcsb pdb:1K0C|rcsb pdb:1K0D|go:"GO:0003714"(transcription corepressor activity)|dip:DIP-1308N psi-mi:"MI:0469"(intact) - crc64:2C628976034B0F1C figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1ew4mfY/9XgnU+IKchGcVFXXDJY559292 rogid:jjsWygBsEp8axNurMa3pxPMQJ2k559292 intact-crc:CB9F92850AEE0F88|rigid:5+5nczrLUEhuyZ7bvbPkhAPIbGI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39958 uniprotkb:P51996 intact:EBI-7517|uniprotkb:D3DM41|ensemblfungi:YER136W intact:EBI-29384|uniprotkb:D6VTU5|ensemblfungi:YGL210W psi-mi:gdi1_yeast(display_long)|uniprotkb:YER136W(locus name)|uniprotkb:GDI1(gene name)|psi-mi:GDI1(display_short)|uniprotkb:SEC19(gene name synonym)|uniprotkb:Secretory pathway GDP dissociation inhibitor(gene name synonym) psi-mi:ypt32_yeast(display_long)|uniprotkb:Rab GTPase YPT32(gene name synonym)|uniprotkb:YPT32(gene name)|psi-mi:YPT32(display_short)|uniprotkb:YPT11(gene name synonym)|uniprotkb:YGL210W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335654|imex:IM-14275-1975 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011062.1|sgd:S000000938|mint:P39958|dip:DIP-785N|ensemblfungi:YER136W(gene)|ensemblfungi:YER136W_mRNA(transcript)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|rcsb pdb:1UKV|rcsb pdb:2BCG|rcsb pdb:3CPH|rcsb pdb:3CPI|rcsb pdb:3CPJ|reactome:R-SCE-6798695|reactome:R-SCE-8876198 refseq:NP_011305.1|sgd:S000003178|dip:DIP-6597N|mint:P51996|ensemblfungi:YGL210W(gene)|ensemblfungi:YGL210W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0055037"(recycling endosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:3RWM|rcsb pdb:3RWO|reactome:R-SCE-5620912|reactome:R-SCE-8873719 psi-mi:"MI:0469"(intact) crc64:48CF8D45FC031772 crc64:621217A296161964 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AkWsG1VUBGxajiAMw0e0mOljZ6s559292 rogid:XwLPzvpvcnztXzxpSBqsQgphFVA559292 intact-crc:0250674CDF2D9008|rigid:sdczpj5PJinRWt0lMd+9+xxIUz4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51996 uniprotkb:P54783 intact:EBI-29384|uniprotkb:D6VTU5|ensemblfungi:YGL210W intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:ypt32_yeast(display_long)|uniprotkb:Rab GTPase YPT32(gene name synonym)|uniprotkb:YPT32(gene name)|psi-mi:YPT32(display_short)|uniprotkb:YPT11(gene name synonym)|uniprotkb:YGL210W(locus name) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335665|imex:IM-14275-1976 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011305.1|sgd:S000003178|dip:DIP-6597N|mint:P51996|ensemblfungi:YGL210W(gene)|ensemblfungi:YGL210W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0055037"(recycling endosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:3RWM|rcsb pdb:3RWO|reactome:R-SCE-5620912|reactome:R-SCE-8873719 go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) crc64:621217A296161964 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XwLPzvpvcnztXzxpSBqsQgphFVA559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:AD4B56EB7E45A639|rigid:pNuNaY09pvtMjxosdm3l2/ttItg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P52490 uniprotkb:P40210 intact:EBI-19777|uniprotkb:D6VS79|ensemblfungi:YDR092W intact:EBI-27280|uniprotkb:D6VZW3|ensemblfungi:YMR140W psi-mi:ubc13_yeast(display_long)|uniprotkb:UBC13(gene name)|psi-mi:UBC13(display_short)|uniprotkb:YDR092W(locus name)|uniprotkb:YD6652.04(orf name)|uniprotkb:Ubiquitin-protein ligase 13(gene name synonym)|uniprotkb:Ubiquitin carrier protein 13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 13(gene name synonym) psi-mi:sip5_yeast(display_long)|uniprotkb:YMR140W(locus name)|uniprotkb:YM9375.09(orf name)|uniprotkb:SIP5(gene name)|psi-mi:SIP5(display_short)|uniprotkb:SNF1-interacting protein 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335676|imex:IM-14275-1977 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002499|ensemblfungi:YDR092W(gene)|ensemblfungi:YDR092W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006301"(postreplication repair)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0044395"(protein targeting to vacuolar membrane)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1JAT|rcsb pdb:1JBB|rcsb pdb:2GMI|rcsb pdb:4FH1|rcsb pdb:5OJW|reactome:R-SCE-8866654|reactome:R-SCE-9020702|reactome:R-SCE-9646399|reactome:R-SCE-983168|refseq:NP_010377.3|dip:DIP-5486N|mint:P52490 sgd:S000004748|refseq:NP_013860.1|mint:P40210|dip:DIP-4656N|ensemblfungi:YMR140W(gene)|ensemblfungi:YMR140W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0042149"(cellular response to glucose starvation)|interpro:IPR039301 psi-mi:"MI:0469"(intact) crc64:445558F8F193275B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5nTtjUZ2IpzHhrj1UU6NlaRW53k559292 rogid:6WSFQ9V598lJW1o+h2DCP7vRyeA559292 intact-crc:166FB52D68978B65|rigid:1npb75fmrdoE4dvW8xzkRoqePS4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P52490 uniprotkb:P53152 intact:EBI-19777|uniprotkb:D6VS79|ensemblfungi:YDR092W intact:EBI-11035|ensemblfungi:YGL087C|uniprotkb:D6VU57 psi-mi:ubc13_yeast(display_long)|uniprotkb:UBC13(gene name)|psi-mi:UBC13(display_short)|uniprotkb:YDR092W(locus name)|uniprotkb:YD6652.04(orf name)|uniprotkb:Ubiquitin-protein ligase 13(gene name synonym)|uniprotkb:Ubiquitin carrier protein 13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 13(gene name synonym) psi-mi:mms2_yeast(display_long)|uniprotkb:MMS2(gene name)|psi-mi:MMS2(display_short)|uniprotkb:YGL087C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335687|imex:IM-14275-1978 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002499|ensemblfungi:YDR092W(gene)|ensemblfungi:YDR092W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006301"(postreplication repair)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0044395"(protein targeting to vacuolar membrane)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1JAT|rcsb pdb:1JBB|rcsb pdb:2GMI|rcsb pdb:4FH1|rcsb pdb:5OJW|reactome:R-SCE-8866654|reactome:R-SCE-9020702|reactome:R-SCE-9646399|reactome:R-SCE-983168|refseq:NP_010377.3|dip:DIP-5486N|mint:P52490 go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006301"(postreplication repair)|ensemblfungi:YGL087C(gene)|ensemblfungi:YGL087C_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0016874"(ligase activity)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0044395"(protein targeting to vacuolar membrane)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:1JAT|rcsb pdb:2GMI|rcsb pdb:5OJW|reactome:R-SCE-8866654|reactome:R-SCE-9020702|reactome:R-SCE-9646399|reactome:R-SCE-983168|sgd:S000003055|refseq:NP_011428.1|mint:P53152|dip:DIP-5829N psi-mi:"MI:0469"(intact) crc64:445558F8F193275B crc64:E1DA713C94378795 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5nTtjUZ2IpzHhrj1UU6NlaRW53k559292 rogid:dthbFT/vOgnFoOeCLfng4kqOXwA559292 intact-crc:23DF63034EEFAE60|rigid:2HvOlTQ4q5PxQvQ1MCdFAqHyR3M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20434 uniprotkb:P52553 intact:EBI-15781|uniprotkb:Q02121|ensemblfungi:YBR154C|uniprotkb:D6VQE9 intact:EBI-13260|uniprotkb:D6VYK2|ensemblfungi:YLR200W psi-mi:rpab1_yeast(display_long)|uniprotkb:RPB5(gene name)|psi-mi:RPB5(display_short)|uniprotkb:YBR154C(locus name)|uniprotkb:YBR1204(orf name)|uniprotkb:RPA7(gene name synonym)|uniprotkb:RPC9(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide(gene name synonym)|uniprotkb:ABC27(gene name synonym) psi-mi:pfd6_yeast(display_long)|uniprotkb:YKE2(gene name)|psi-mi:YKE2(display_short)|uniprotkb:PFD6(gene name synonym)|uniprotkb:YLR200W(locus name)|uniprotkb:L8167.8(orf name)|uniprotkb:GIM1(gene name synonym)|uniprotkb:Genes involved in microtubule biogenesis protein 1(gene name synonym)|uniprotkb:Gim complex subunit 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335698|imex:IM-14275-1979 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|rcsb pdb:1WCM|rcsb pdb:1Y1V|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|rcsb pdb:2B63|rcsb pdb:2B8K|interpro:IPR020608|interpro:IPR020609|rcsb pdb:2E2H|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:1DZF|rcsb pdb:1I3Q|rcsb pdb:2E2I|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:5M5Y|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6H67|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:2E2J|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|ensemblfungi:YBR154C(gene)|ensemblfungi:YBR154C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4V1M|rcsb pdb:2JA5|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2JA6|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:2JA7|rcsb pdb:3GTG|rcsb pdb:2JA8|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:2NVQ|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4YM7|rcsb pdb:5C3E|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5G5L|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6H68|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|rcsb pdb:6UQ2|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-77075|reactome:R-SCE-9018519|refseq:NP_009712.1|sgd:S000000358|dip:DIP-71N|mint:P20434 refseq:NP_013301.1|sgd:S000004190|mint:P52553|dip:DIP-1333N|ensemblfungi:YLR200W(gene)|ensemblfungi:YLR200W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin) psi-mi:"MI:0469"(intact) crc64:2A15F7114D69D829 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:j/jAJ2fXWf4ebK1aWTWrKERGUpM559292 rogid:XXTSrL5Q5CrSqYzKV3j3h5/7d10559292 intact-crc:9B5B9BFA1E9222D1|rigid:GSSAZ2LI/6b56We9BfrDU/qAtDg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P52553 uniprotkb:P48363 intact:EBI-13260|uniprotkb:D6VYK2|ensemblfungi:YLR200W intact:EBI-13239|uniprotkb:D6VUL0|ensemblfungi:YGR078C psi-mi:pfd6_yeast(display_long)|uniprotkb:YKE2(gene name)|psi-mi:YKE2(display_short)|uniprotkb:PFD6(gene name synonym)|uniprotkb:YLR200W(locus name)|uniprotkb:L8167.8(orf name)|uniprotkb:GIM1(gene name synonym)|uniprotkb:Genes involved in microtubule biogenesis protein 1(gene name synonym)|uniprotkb:Gim complex subunit 1(gene name synonym) psi-mi:pfd3_yeast(display_long)|uniprotkb:PAC10(gene name)|psi-mi:PAC10(display_short)|uniprotkb:PFD3(gene name synonym)|uniprotkb:GIM2(gene name synonym)|uniprotkb:YGR078C(locus name)|uniprotkb:Genes involved in microtubule biogenesis protein 2(gene name synonym)|uniprotkb:Gim complex subunit 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335709|imex:IM-14275-1980 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013301.1|sgd:S000004190|mint:P52553|dip:DIP-1333N|ensemblfungi:YLR200W(gene)|ensemblfungi:YLR200W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin) refseq:NP_011592.3|sgd:S000003310|mint:P48363|dip:DIP-6837N|ensemblfungi:YGR078C(gene)|ensemblfungi:YGR078C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006457"(protein folding)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016655(Prefoldin, subunit 3) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XXTSrL5Q5CrSqYzKV3j3h5/7d10559292 rogid:PgfsZGjmKc7Kt2dTnjkCzhzQflY559292 intact-crc:2849C18E7CA9637A|rigid:ZIHN3d+yiurjgjk2cxtmKjIbZWs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P52553 uniprotkb:P53900 intact:EBI-13260|uniprotkb:D6VYK2|ensemblfungi:YLR200W intact:EBI-13246|uniprotkb:D6W130|ensemblfungi:YNL153C psi-mi:pfd6_yeast(display_long)|uniprotkb:YKE2(gene name)|psi-mi:YKE2(display_short)|uniprotkb:PFD6(gene name synonym)|uniprotkb:YLR200W(locus name)|uniprotkb:L8167.8(orf name)|uniprotkb:GIM1(gene name synonym)|uniprotkb:Genes involved in microtubule biogenesis protein 1(gene name synonym)|uniprotkb:Gim complex subunit 1(gene name synonym) psi-mi:pfd4_yeast(display_long)|uniprotkb:GIM3(gene name)|psi-mi:GIM3(display_short)|uniprotkb:PFD4(gene name synonym)|uniprotkb:YNL153C(locus name)|uniprotkb:N1761(orf name)|uniprotkb:Genes involved in microtubule biogenesis protein 3(gene name synonym)|uniprotkb:Gim complex subunit 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335720|imex:IM-14275-1981 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013301.1|sgd:S000004190|mint:P52553|dip:DIP-1333N|ensemblfungi:YLR200W(gene)|ensemblfungi:YLR200W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin) refseq:NP_014246.1|sgd:S000005097|mint:P53900|dip:DIP-3000N|ensemblfungi:YNL153C(gene)|ensemblfungi:YNL153C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016661(Prefoldin, subunit 4) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XXTSrL5Q5CrSqYzKV3j3h5/7d10559292 rogid:TdRDErsc5xwqaEqpI4SSCW0sCsg559292 intact-crc:E965B4AD12142750|rigid:Qo7TOoyBZdqc/w05W2XG8+dG2qg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P52553 uniprotkb:Q04493 intact:EBI-13260|uniprotkb:D6VYK2|ensemblfungi:YLR200W intact:EBI-13253|uniprotkb:D6W0J1|ensemblfungi:YML094W psi-mi:pfd6_yeast(display_long)|uniprotkb:YKE2(gene name)|psi-mi:YKE2(display_short)|uniprotkb:PFD6(gene name synonym)|uniprotkb:YLR200W(locus name)|uniprotkb:L8167.8(orf name)|uniprotkb:GIM1(gene name synonym)|uniprotkb:Genes involved in microtubule biogenesis protein 1(gene name synonym)|uniprotkb:Gim complex subunit 1(gene name synonym) psi-mi:pfd5_yeast(display_long)|uniprotkb:GIM5(gene name)|psi-mi:GIM5(display_short)|uniprotkb:PFD5(gene name synonym)|uniprotkb:YML094W(locus name)|uniprotkb:Genes involved in microtubule biogenesis protein 5(gene name synonym)|uniprotkb:Gim complex subunit 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335731|imex:IM-14275-1982 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013301.1|sgd:S000004190|mint:P52553|dip:DIP-1333N|ensemblfungi:YLR200W(gene)|ensemblfungi:YLR200W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin) refseq:NP_013616.1|sgd:S000004559|mint:Q04493|dip:DIP-1332N|ensemblfungi:YML094W(gene)|ensemblfungi:YML094W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR011599(Prefoldin alpha subunit) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XXTSrL5Q5CrSqYzKV3j3h5/7d10559292 rogid:+I6WXFpL1knsCu3DsbMiC4LqDVo559292 intact-crc:B16E1F354ABE62CA|rigid:+4W9OKgtojJb6Ia2JoaLyW7FCxg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P52553 uniprotkb:Q8TGU5 intact:EBI-13260|uniprotkb:D6VYK2|ensemblfungi:YLR200W intact:EBI-2042814|uniprotkb:D6VQU1|ensemblfungi:YBR296C-A psi-mi:pfd6_yeast(display_long)|uniprotkb:YKE2(gene name)|psi-mi:YKE2(display_short)|uniprotkb:PFD6(gene name synonym)|uniprotkb:YLR200W(locus name)|uniprotkb:L8167.8(orf name)|uniprotkb:GIM1(gene name synonym)|uniprotkb:Genes involved in microtubule biogenesis protein 1(gene name synonym)|uniprotkb:Gim complex subunit 1(gene name synonym) psi-mi:yb296_yeast(display_long)|uniprotkb:YBR296C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335742|imex:IM-14275-1983 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013301.1|sgd:S000004190|mint:P52553|dip:DIP-1333N|ensemblfungi:YLR200W(gene)|ensemblfungi:YLR200W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin) sgd:S000028605|refseq:NP_878055.3|mint:Q8TGU5|ensemblfungi:YBR296C-A(gene)|ensemblfungi:YBR296C-A_mRNA(transcript)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XXTSrL5Q5CrSqYzKV3j3h5/7d10559292 rogid:DZubWD7lnwtea4Ne/bK1ITPFaJk559292 intact-crc:C88D11F06FC25F2C|rigid:ol00ggW+QaBcjoWgg/OW8ibvrfE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P52893 uniprotkb:Q03370 intact:EBI-2434|uniprotkb:D6VY89|ensemblfungi:YLR089C intact:EBI-36170|uniprotkb:D6VTA2|ensemblfungi:YDR479C psi-mi:alam_yeast(display_long)|uniprotkb:YLR089C(locus name)|uniprotkb:L9449.15(orf name)|uniprotkb:ALT1(gene name)|psi-mi:ALT1(display_short)|uniprotkb:Glutamic--pyruvic transaminase(gene name synonym)|uniprotkb:Glutamate pyruvate transaminase(gene name synonym)|uniprotkb:Glutamic--alanine transaminase(gene name synonym) psi-mi:pex29_yeast(display_long)|uniprotkb:PEX29(gene name)|psi-mi:PEX29(display_short)|uniprotkb:Peroxin-29(gene name synonym)|uniprotkb:YDR479C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335753|imex:IM-14275-1984 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013190.1|sgd:S000004079|dip:DIP-7654N|mint:P52893|ensemblfungi:YLR089C(gene)|ensemblfungi:YLR089C_mRNA(transcript)|go:"GO:0004021"("L-alanine:2-oxoglutarate aminotransferase activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006523"(alanine biosynthetic process)|go:"GO:0006524"(alanine catabolic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042853"(L-alanine catabolic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|reactome:R-SCE-8964540 refseq:NP_010767.1|sgd:S000002887|mint:Q03370|dip:DIP-5175N|ensemblfungi:YDR479C(gene)|ensemblfungi:YDR479C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032581"(ER-dependent peroxisome organization)|interpro:IPR010482(Integral peroxisomal membrane peroxin) psi-mi:"MI:0469"(intact) - crc64:C2EB849C36FB69EB figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VvgTAQHIwpSHqjdbmvyExoTlDCg559292 rogid:XirbTI20sgYx5DDsELcnS9RLxMw559292 intact-crc:9AB44EFDE09F99C4|rigid:h+NeRTThkqSUt21M1+pDs6KtCR0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06263 uniprotkb:P52917 intact:EBI-37098|uniprotkb:Q07057|uniprotkb:D6VYI5|ensemblfungi:YLR181C intact:EBI-20475|uniprotkb:D6W4H4|ensemblfungi:YPR173C psi-mi:vta1_yeast(display_long)|uniprotkb:VTA1(gene name)|psi-mi:VTA1(display_short)|uniprotkb:YLR181C(locus name)|uniprotkb:VPS20-associated protein 1(gene name synonym) psi-mi:vps4_yeast(display_long)|uniprotkb:VPS4(gene name)|psi-mi:VPS4(display_short)|uniprotkb:CSC1(gene name synonym)|uniprotkb:END13(gene name synonym)|uniprotkb:GRD13(gene name synonym)|uniprotkb:DID6(gene name synonym)|uniprotkb:Protein END13(gene name synonym)|uniprotkb:DOA4-independent degradation protein 6(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 10(gene name synonym)|uniprotkb:VPL4(gene name synonym)|uniprotkb:VPT10(gene name synonym)|uniprotkb:P9705.10(orf name)|uniprotkb:YPR173C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335764|imex:IM-14275-1985 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013282.1|sgd:S000004171|mint:Q06263|dip:DIP-4802N|ensemblfungi:YLR181C(gene)|ensemblfungi:YLR181C_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0006869"(lipid transport)|go:"GO:0015031"(protein transport)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR023175|interpro:IPR039431|interpro:IPR041212|interpro:IPR044538|rcsb pdb:2LUH|rcsb pdb:2RKK|rcsb pdb:2RKL|rcsb pdb:3MHV|rcsb pdb:5H7P|rcsb pdb:5UIE|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6OO2|reactome:R-SCE-917729 refseq:NP_015499.1|sgd:S000006377|ensemblfungi:YPR173C(gene)|ensemblfungi:YPR173C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007033"(vacuole organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|rcsb pdb:2QP9|rcsb pdb:2QPA|rcsb pdb:2RKO|rcsb pdb:2V6X|rcsb pdb:3EIE|rcsb pdb:3EIH|rcsb pdb:3MHV|rcsb pdb:4NIQ|rcsb pdb:5FVK|rcsb pdb:5FVL|rcsb pdb:5UIE|rcsb pdb:5XMI|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6BMF|rcsb pdb:6NDY|rcsb pdb:6OO2|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1746N|mint:P52917 psi-mi:"MI:0469"(intact) crc64:BB6E6975596C1674 crc64:E65BCDB19C9510DD figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:X9sRQb1nZECFkdjvDUTjxEgokRM559292 rogid:qXGTfZcBZ9jWOVjm6tl3wIR/ngM559292 intact-crc:64D61766268E0492|rigid:ZkYaBeo5GdpVL8W0dCXO02pgPUw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53008 uniprotkb:Q6Q5K6 intact:EBI-5323|uniprotkb:D6VUB1|ensemblfungi:YGL027C intact:EBI-392766|ensemblfungi:YML058W-A|uniprotkb:D6VZB5 psi-mi:cwh41_yeast(display_long)|uniprotkb:CWH41(gene name)|psi-mi:CWH41(display_short)|uniprotkb:GLS1(gene name synonym)|uniprotkb:Processing A-glucosidase I(gene name synonym)|uniprotkb:YGL027C(locus name) psi-mi:hug1_yeast(display_long)|uniprotkb:HUG1(gene name)|psi-mi:HUG1(display_short)|uniprotkb:YML058W-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335775|imex:IM-14275-1986 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011488.1|sgd:S000002995|dip:DIP-5301N|mint:P53008|ensemblfungi:YGL027C(gene)|ensemblfungi:YGL027C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004573"(Glc3Man9GlcNAc2 oligosaccharide glucosidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0009311"(oligosaccharide metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070880"(fungal-type cell wall beta-glucan biosynthetic process)|interpro:IPR004888(Glycoside hydrolase, family 63)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR031335|interpro:IPR031631|interpro:IPR038518|rcsb pdb:4J5T ensemblfungi:YML058W-A(gene)|ensemblfungi:YML058W-A_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:1905117"(regulation of ribonucleoside-diphosphate reductase activity)|go:"GO:1990846"(ribonucleoside-diphosphate reductase inhibitor activity)|sgd:S000007472|refseq:NP_219498.1|mint:Q6Q5K6 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:paOIVSkf8KH5cLuPZZqbxt2TSrU559292 rogid:x+quBrnP+8yql7JGQ1NK4j5ubbw559292 intact-crc:64760FEEB0B46EE3|rigid:MZ53H8A0RODgZ8uZ9a1bM7ekaY8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40965 uniprotkb:P53038 intact:EBI-11371|ensemblfungi:YFL003C|uniprotkb:D6VTM6 intact:EBI-19106|uniprotkb:D6VUN1|ensemblfungi:YGR099W psi-mi:msh4_yeast(display_long)|uniprotkb:MSH4(gene name)|psi-mi:MSH4(display_short)|uniprotkb:YFL003C(locus name) psi-mi:tel2_yeast(display_long)|uniprotkb:YGR099W(locus name)|uniprotkb:TEL2(gene name)|psi-mi:TEL2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335786|imex:IM-14275-1987 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YFL003C(gene)|ensemblfungi:YFL003C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005524"(ATP binding)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0062128"(MutSgamma complex)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|refseq:NP_116652.1|sgd:S000001891|mint:P40965|dip:DIP-2426N sgd:S000003331|ensemblfungi:YGR099W(gene)|ensemblfungi:YGR099W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005829"(cytosol)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070209"(ASTRA complex)|interpro:IPR019337|interpro:IPR038528|rcsb pdb:3O4Z|refseq:NP_011613.3|dip:DIP-1245N|mint:P53038 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iFhkRrFx9rw2iRzg7gJfv5eZwXk559292 rogid:SZibPBili0M8YgHIwxf+sKkLk+M559292 intact-crc:CC72D2FEF9F73BBD|rigid:ojh7PiKrATVRemFwVCoAOArJS38 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15496 uniprotkb:P53040 intact:EBI-8902|ensemblfungi:YPL117C|uniprotkb:D6W3Q1 intact:EBI-18876|uniprotkb:D6VU35|ensemblfungi:YGL112C psi-mi:idi1_yeast(display_long)|uniprotkb:Isopentenyl pyrophosphate isomerase(gene name synonym)|uniprotkb:IDI1(gene name)|psi-mi:IDI1(display_short)|uniprotkb:BOT2(gene name synonym)|uniprotkb:YPL117C(locus name)|uniprotkb:LPH10C(orf name) psi-mi:taf6_yeast(display_long)|uniprotkb:TAF6(gene name)|psi-mi:TAF6(display_short)|uniprotkb:TAF60(gene name synonym)|uniprotkb:YGL112C(locus name)|uniprotkb:G2985(orf name)|uniprotkb:TBP-associated factor 6(gene name synonym)|uniprotkb:TBP-associated factor 60 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335797|imex:IM-14275-1988 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL117C(gene)|ensemblfungi:YPL117C_mRNA(transcript)|go:"GO:0004452"(isopentenyl-diphosphate delta-isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009240"(isopentenyl diphosphate biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0045337"(farnesyl diphosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050992"(dimethylallyl diphosphate biosynthetic process)|reactome:R-SCE-191273|refseq:NP_015208.1|sgd:S000006038|interpro:IPR011876(Isopentenyl-diphosphate delta-isomerase, type 1)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|mint:P15496 refseq:NP_011403.1|sgd:S000003080|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR011442(Protein of unknown function DUF1546)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037796|rcsb pdb:6T9I|rcsb pdb:6T9K|reactome:R-SCE-674695|reactome:R-SCE-6807505|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-76042|ensemblfungi:YGL112C(gene)|ensemblfungi:YGL112C_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|dip:DIP-981N|mint:P53040 psi-mi:"MI:0469"(intact) - crc64:14B590E02C16F289 figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:KQ9qSb2grQ4DQip7atYPeCwp5QM559292 rogid:qmzBE/xAfQskdJqoI8oIqAIa3+A559292 intact-crc:EA612D243D7CB941|rigid:IN6+OfSZV8HTgGcI+naKj05HpPo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04228 uniprotkb:P53044 intact:EBI-27730|uniprotkb:D6VZG1|ensemblfungi:YML013W intact:EBI-19997|uniprotkb:D6VUI5|uniprotkb:Q45U36|ensemblfungi:YGR048W psi-mi:ubx2_yeast(display_long)|uniprotkb:SEL1(gene name synonym)|uniprotkb:YM9571.05(orf name)|uniprotkb:YML013W(locus name)|uniprotkb:UBX2(gene name)|psi-mi:UBX2(display_short)|uniprotkb:Secretion lowering protein 1(gene name synonym) psi-mi:ufd1_yeast(display_long)|uniprotkb:UFD1(gene name)|psi-mi:UFD1(display_short)|uniprotkb:PIP3(gene name synonym)|uniprotkb:Polymerase-interacting protein 3(gene name synonym)|uniprotkb:YGR048W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335808|imex:IM-14275-1989 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013699.1|sgd:S000004475|dip:DIP-5073N|mint:Q04228|ensemblfungi:YML013W(gene)|ensemblfungi:YML013W_mRNA(transcript)|go:"GO:0000837"(Doa10p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001012(UBX) refseq:NP_011562.1|sgd:S000003280|go:"GO:0006274"(DNA replication termination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030894"(replisome)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1990112"(RQC complex)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|interpro:IPR004854(Ubiquitin fusion degradation protein UFD1)|interpro:IPR042299|rcsb pdb:1ZC1|rcsb pdb:6JWJ|reactome:R-SCE-110320|ensemblfungi:YGR048W(gene)|ensemblfungi:YGR048W_mRNA(transcript)|go:"GO:0000837"(Doa10p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|dip:DIP-1476N|mint:P53044 psi-mi:"MI:0469"(intact) crc64:DA4DDD3D624C17B8 crc64:198E0CD48B863B98 figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pHZ9MnjC5Y3aC5hV43Z4fmkqI8w559292 rogid:u/YG6aRuJ38NLsxGkUsfM9nXAnU559292 intact-crc:3656A0A25C52ECCD|rigid:xn+G/dqSR0utaDf1TDQ/Uv3ywWA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P53045 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-6506|uniprotkb:D6VUJ5|uniprotkb:Q45U26|uniprotkb:E9P8T3|ensemblfungi:YGR060W psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:msmo_yeast(display_long)|uniprotkb:ERG25(gene name)|psi-mi:ERG25(display_short)|uniprotkb:FET6(gene name synonym)|uniprotkb:C-4 methylsterol oxidase(gene name synonym)|uniprotkb:Sterol-C4-methyl oxidase(gene name synonym)|uniprotkb:YGR060W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335819|imex:IM-14275-1990 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 sgd:S000003292|refseq:NP_011574.3|mint:P53045|dip:DIP-2799N|ensemblfungi:YGR060W(gene)|ensemblfungi:YGR060W_mRNA(transcript)|go:"GO:0000254"(C-4 methylsterol oxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-SCE-191273|reactome:R-SCE-192105 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:Ry0sO64GCCLYt4w5HaTb6IO+1+Y559292 intact-crc:25E3A916D0480EBB|rigid:xCFzJReMghAla3qEPthz+t8TLbo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53045 uniprotkb:P26570 intact:EBI-6506|uniprotkb:D6VUJ5|uniprotkb:Q45U26|uniprotkb:E9P8T3|ensemblfungi:YGR060W intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 psi-mi:msmo_yeast(display_long)|uniprotkb:ERG25(gene name)|psi-mi:ERG25(display_short)|uniprotkb:FET6(gene name synonym)|uniprotkb:C-4 methylsterol oxidase(gene name synonym)|uniprotkb:Sterol-C4-methyl oxidase(gene name synonym)|uniprotkb:YGR060W(locus name) psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335830|imex:IM-14275-1991 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003292|refseq:NP_011574.3|mint:P53045|dip:DIP-2799N|ensemblfungi:YGR060W(gene)|ensemblfungi:YGR060W_mRNA(transcript)|go:"GO:0000254"(C-4 methylsterol oxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-SCE-191273|reactome:R-SCE-192105 ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N psi-mi:"MI:0469"(intact) - crc64:8B7F009521F72C15 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ry0sO64GCCLYt4w5HaTb6IO+1+Y559292 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 intact-crc:BD546A739D2CA6EA|rigid:KWUdiOs15+p8KJmnLyVqVtPvWyo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53045 uniprotkb:P32353 intact:EBI-6506|uniprotkb:D6VUJ5|uniprotkb:Q45U26|uniprotkb:E9P8T3|ensemblfungi:YGR060W intact:EBI-6554|uniprotkb:D6VY58|ensemblfungi:YLR056W psi-mi:msmo_yeast(display_long)|uniprotkb:ERG25(gene name)|psi-mi:ERG25(display_short)|uniprotkb:FET6(gene name synonym)|uniprotkb:C-4 methylsterol oxidase(gene name synonym)|uniprotkb:Sterol-C4-methyl oxidase(gene name synonym)|uniprotkb:YGR060W(locus name) psi-mi:erg3_yeast(display_long)|uniprotkb:SYR1(gene name synonym)|uniprotkb:L2150(orf name)|uniprotkb:YLR056W(locus name)|uniprotkb:ERG3(gene name)|psi-mi:ERG3(display_short)|uniprotkb:PSO6(gene name synonym)|uniprotkb:Sterol-C5-desaturase(gene name synonym)|uniprotkb:"Ergosterol Delta(5,6) desaturase"(gene name synonym)|uniprotkb:C-5 sterol desaturase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335841|imex:IM-14275-1992 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003292|refseq:NP_011574.3|mint:P53045|dip:DIP-2799N|ensemblfungi:YGR060W(gene)|ensemblfungi:YGR060W_mRNA(transcript)|go:"GO:0000254"(C-4 methylsterol oxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-SCE-191273|reactome:R-SCE-192105 refseq:NP_013157.1|sgd:S000004046|mint:P32353|dip:DIP-4136N|ensemblfungi:YLR056W(gene)|ensemblfungi:YLR056W_mRNA(transcript)|go:"GO:0000248"(C-5 sterol desaturase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0050046"("delta7-sterol 5(6)-desaturase activity")|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-SCE-6807047|reactome:R-SCE-6807062 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ry0sO64GCCLYt4w5HaTb6IO+1+Y559292 rogid:zO926fj34KkGCJAI6vTmiICpUSc559292 intact-crc:6EB36F15337760F8|rigid:VNsaXcvVsxt58yqVr5fHrJaFTjQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53045 uniprotkb:P32915 intact:EBI-6506|uniprotkb:D6VUJ5|uniprotkb:Q45U26|uniprotkb:E9P8T3|ensemblfungi:YGR060W intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 psi-mi:msmo_yeast(display_long)|uniprotkb:ERG25(gene name)|psi-mi:ERG25(display_short)|uniprotkb:FET6(gene name synonym)|uniprotkb:C-4 methylsterol oxidase(gene name synonym)|uniprotkb:Sterol-C4-methyl oxidase(gene name synonym)|uniprotkb:YGR060W(locus name) psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335852|imex:IM-14275-1993 author score:97.40 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003292|refseq:NP_011574.3|mint:P53045|dip:DIP-2799N|ensemblfungi:YGR060W(gene)|ensemblfungi:YGR060W_mRNA(transcript)|go:"GO:0000254"(C-4 methylsterol oxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-SCE-191273|reactome:R-SCE-192105 go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ry0sO64GCCLYt4w5HaTb6IO+1+Y559292 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 intact-crc:FF92A3CEA72B462A|rigid:LQ3yfFfttZb0RGWMiRqR+6oOfVc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53045 uniprotkb:P38142 intact:EBI-6506|uniprotkb:D6VUJ5|uniprotkb:Q45U26|uniprotkb:E9P8T3|ensemblfungi:YGR060W intact:EBI-21079|uniprotkb:D6VQN7|intact:EBI-2347460|uniprotkb:Q6B2Y5|ensemblfungi:YBR241C psi-mi:msmo_yeast(display_long)|uniprotkb:ERG25(gene name)|psi-mi:ERG25(display_short)|uniprotkb:FET6(gene name synonym)|uniprotkb:C-4 methylsterol oxidase(gene name synonym)|uniprotkb:Sterol-C4-methyl oxidase(gene name synonym)|uniprotkb:YGR060W(locus name) psi-mi:yb91_yeast(display_long)|uniprotkb:YBR1625(orf name)|uniprotkb:YBR241C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335863|imex:IM-14275-1994 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003292|refseq:NP_011574.3|mint:P53045|dip:DIP-2799N|ensemblfungi:YGR060W(gene)|ensemblfungi:YGR060W_mRNA(transcript)|go:"GO:0000254"(C-4 methylsterol oxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-SCE-191273|reactome:R-SCE-192105 refseq:NP_009800.1|sgd:S000000445|mint:P38142|dip:DIP-5363N|ensemblfungi:YBR241C(gene)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|reactome:R-SCE-189200|reactome:R-SCE-196836|reactome:R-SCE-422356|reactome:R-SCE-5653890|reactome:R-SCE-6798695|reactome:R-SCE-8981373|ensemblfungi:YBR241C_mRNA(transcript) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ry0sO64GCCLYt4w5HaTb6IO+1+Y559292 rogid:B0qgnhfd17hrDGLrJ21KY/FCzTQ559292 intact-crc:09060A0B8B0AD740|rigid:usBoGxeAfC4jCjhevqK/7uHQqHs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:P53045 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-6506|uniprotkb:D6VUJ5|uniprotkb:Q45U26|uniprotkb:E9P8T3|ensemblfungi:YGR060W psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:msmo_yeast(display_long)|uniprotkb:ERG25(gene name)|psi-mi:ERG25(display_short)|uniprotkb:FET6(gene name synonym)|uniprotkb:C-4 methylsterol oxidase(gene name synonym)|uniprotkb:Sterol-C4-methyl oxidase(gene name synonym)|uniprotkb:YGR060W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335874|imex:IM-14275-1995 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N sgd:S000003292|refseq:NP_011574.3|mint:P53045|dip:DIP-2799N|ensemblfungi:YGR060W(gene)|ensemblfungi:YGR060W_mRNA(transcript)|go:"GO:0000254"(C-4 methylsterol oxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-SCE-191273|reactome:R-SCE-192105 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:Ry0sO64GCCLYt4w5HaTb6IO+1+Y559292 intact-crc:32F5ABC00D68B276|rigid:HDj0n2YmddN4XKsBHVeXGrwwga0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53045 uniprotkb:P38353 intact:EBI-6506|uniprotkb:D6VUJ5|uniprotkb:Q45U26|uniprotkb:E9P8T3|ensemblfungi:YGR060W intact:EBI-18175|uniprotkb:D6VQS8|ensemblfungi:YBR283C psi-mi:msmo_yeast(display_long)|uniprotkb:ERG25(gene name)|psi-mi:ERG25(display_short)|uniprotkb:FET6(gene name synonym)|uniprotkb:C-4 methylsterol oxidase(gene name synonym)|uniprotkb:Sterol-C4-methyl oxidase(gene name synonym)|uniprotkb:YGR060W(locus name) psi-mi:ssh1_yeast(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:Ssh1 complex subunit alpha(gene name synonym)|uniprotkb:Ssh1 complex subunit SSH1(gene name synonym)|uniprotkb:YBR2020(orf name)|uniprotkb:YBR283C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335885|imex:IM-14275-1996 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003292|refseq:NP_011574.3|mint:P53045|dip:DIP-2799N|ensemblfungi:YGR060W(gene)|ensemblfungi:YGR060W_mRNA(transcript)|go:"GO:0000254"(C-4 methylsterol oxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-SCE-191273|reactome:R-SCE-192105 refseq:NP_009842.1|sgd:S000000487|ensemblfungi:YBR283C(gene)|ensemblfungi:YBR283C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:2WW9|rcsb pdb:2WWA|dip:DIP-4962N|mint:P38353 psi-mi:"MI:0469"(intact) - crc64:48267EEA3E0191BD figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ry0sO64GCCLYt4w5HaTb6IO+1+Y559292 rogid:76wvZIdv7W5BQn6wI+sHOGQAyuc559292 intact-crc:4AB9CADF32C74C69|rigid:D+CjKzmxz8I7Jr3HGNNtphx2RVQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53045 uniprotkb:P40207 intact:EBI-6506|uniprotkb:D6VUJ5|uniprotkb:Q45U26|uniprotkb:E9P8T3|ensemblfungi:YGR060W intact:EBI-27272|uniprotkb:D6VZV7|ensemblfungi:YMR134W psi-mi:msmo_yeast(display_long)|uniprotkb:ERG25(gene name)|psi-mi:ERG25(display_short)|uniprotkb:FET6(gene name synonym)|uniprotkb:C-4 methylsterol oxidase(gene name synonym)|uniprotkb:Sterol-C4-methyl oxidase(gene name synonym)|uniprotkb:YGR060W(locus name) psi-mi:erg29_yeast(display_long)|uniprotkb:ERG29(gene name)|psi-mi:ERG29(display_short)|uniprotkb:YM9375.03(orf name)|uniprotkb:YMR134W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335896|imex:IM-14275-1997 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003292|refseq:NP_011574.3|mint:P53045|dip:DIP-2799N|ensemblfungi:YGR060W(gene)|ensemblfungi:YGR060W_mRNA(transcript)|go:"GO:0000254"(C-4 methylsterol oxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-SCE-191273|reactome:R-SCE-192105 refseq:NP_013853.1|sgd:S000004741|mint:P40207|dip:DIP-4433N|ensemblfungi:YMR134W(gene)|ensemblfungi:YMR134W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ry0sO64GCCLYt4w5HaTb6IO+1+Y559292 rogid:6ByNiLUswj10x66D1WrAHOI9t7c559292 intact-crc:73752849F66D2A15|rigid:omQ30u8THnOY0axOJ4cOgquOc1A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53045 uniprotkb:P40350 intact:EBI-6506|uniprotkb:D6VUJ5|uniprotkb:Q45U26|uniprotkb:E9P8T3|ensemblfungi:YGR060W intact:EBI-2470|uniprotkb:D6W3E3|ensemblfungi:YPL227C psi-mi:msmo_yeast(display_long)|uniprotkb:ERG25(gene name)|psi-mi:ERG25(display_short)|uniprotkb:FET6(gene name synonym)|uniprotkb:C-4 methylsterol oxidase(gene name synonym)|uniprotkb:Sterol-C4-methyl oxidase(gene name synonym)|uniprotkb:YGR060W(locus name) psi-mi:alg5_yeast(display_long)|uniprotkb:ALG5(gene name)|psi-mi:ALG5(display_short)|uniprotkb:YPL227C(locus name)|uniprotkb:P1437(orf name)|uniprotkb:Asparagine-linked glycosylation protein 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335907|imex:IM-14275-1998 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003292|refseq:NP_011574.3|mint:P53045|dip:DIP-2799N|ensemblfungi:YGR060W(gene)|ensemblfungi:YGR060W_mRNA(transcript)|go:"GO:0000254"(C-4 methylsterol oxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-SCE-191273|reactome:R-SCE-192105 refseq:NP_015097.1|sgd:S000006148|dip:DIP-5651N|mint:P40350|ensemblfungi:YPL227C(gene)|ensemblfungi:YPL227C_mRNA(transcript)|go:"GO:0004581"(dolichyl-phosphate beta-glucosyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR035518|reactome:R-SCE-480985 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ry0sO64GCCLYt4w5HaTb6IO+1+Y559292 rogid:aKi97cbwqo7kNWhtRyzG3UOLH4U559292 intact-crc:D87F4B86D24DC15B|rigid:pA2ivUSVQgZauTjnc/Iv3L6WJk4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40540 uniprotkb:P53045 intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C intact:EBI-6506|uniprotkb:D6VUJ5|uniprotkb:Q45U26|uniprotkb:E9P8T3|ensemblfungi:YGR060W psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:msmo_yeast(display_long)|uniprotkb:ERG25(gene name)|psi-mi:ERG25(display_short)|uniprotkb:FET6(gene name synonym)|uniprotkb:C-4 methylsterol oxidase(gene name synonym)|uniprotkb:Sterol-C4-methyl oxidase(gene name synonym)|uniprotkb:YGR060W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335918|imex:IM-14275-1999 author score:97.40 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX sgd:S000003292|refseq:NP_011574.3|mint:P53045|dip:DIP-2799N|ensemblfungi:YGR060W(gene)|ensemblfungi:YGR060W_mRNA(transcript)|go:"GO:0000254"(C-4 methylsterol oxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-SCE-191273|reactome:R-SCE-192105 psi-mi:"MI:0469"(intact) crc64:6DBEEEE7722203B0 - figure legend:tables S3 and S4|author-confidence:97.40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 rogid:Ry0sO64GCCLYt4w5HaTb6IO+1+Y559292 intact-crc:C17D0996DECB37D6|rigid:8YUXbyLLnBquwGve9Ke2VCL/ApA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46956 uniprotkb:P53045 intact:EBI-13337|uniprotkb:E9P8T7|ensemblfungi:YJL117W|uniprotkb:D6VW67 intact:EBI-6506|uniprotkb:D6VUJ5|uniprotkb:Q45U26|uniprotkb:E9P8T3|ensemblfungi:YGR060W psi-mi:pho86_yeast(display_long)|uniprotkb:PHO86(gene name)|psi-mi:PHO86(display_short)|uniprotkb:J0744(orf name)|uniprotkb:YJL117W(locus name) psi-mi:msmo_yeast(display_long)|uniprotkb:ERG25(gene name)|psi-mi:ERG25(display_short)|uniprotkb:FET6(gene name synonym)|uniprotkb:C-4 methylsterol oxidase(gene name synonym)|uniprotkb:Sterol-C4-methyl oxidase(gene name synonym)|uniprotkb:YGR060W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335929|imex:IM-14275-2000 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012418.1|sgd:S000003653|interpro:IPR024297|ensemblfungi:YJL117W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0010966"(regulation of phosphate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051082"(unfolded protein binding)|ensemblfungi:YJL117W(gene)|mint:P46956|dip:DIP-2769N sgd:S000003292|refseq:NP_011574.3|mint:P53045|dip:DIP-2799N|ensemblfungi:YGR060W(gene)|ensemblfungi:YGR060W_mRNA(transcript)|go:"GO:0000254"(C-4 methylsterol oxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-SCE-191273|reactome:R-SCE-192105 psi-mi:"MI:0469"(intact) crc64:1CB19C9184BF1C48 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:JITWReptfMoij1Uy6y1e3Oa6dAs559292 rogid:Ry0sO64GCCLYt4w5HaTb6IO+1+Y559292 intact-crc:58DCE00B5D741A67|rigid:vFUUMX7PaM+FzkNzHLa/uV3wNCo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53045 uniprotkb:P47155 intact:EBI-6506|uniprotkb:D6VUJ5|uniprotkb:Q45U26|uniprotkb:E9P8T3|ensemblfungi:YGR060W intact:EBI-2051644|uniprotkb:D6VWT7|ensemblfungi:YJR118C psi-mi:msmo_yeast(display_long)|uniprotkb:ERG25(gene name)|psi-mi:ERG25(display_short)|uniprotkb:FET6(gene name synonym)|uniprotkb:C-4 methylsterol oxidase(gene name synonym)|uniprotkb:Sterol-C4-methyl oxidase(gene name synonym)|uniprotkb:YGR060W(locus name) psi-mi:ilm1_yeast(display_long)|uniprotkb:Increased loss of mitochondrial DNA protein 1(gene name synonym)|uniprotkb:J2033(orf name)|uniprotkb:ILM1(gene name)|psi-mi:ILM1(display_short)|uniprotkb:YJR118C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335940|imex:IM-14275-2001 author score:97.40 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003292|refseq:NP_011574.3|mint:P53045|dip:DIP-2799N|ensemblfungi:YGR060W(gene)|ensemblfungi:YGR060W_mRNA(transcript)|go:"GO:0000254"(C-4 methylsterol oxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-SCE-191273|reactome:R-SCE-192105 sgd:S000003879|interpro:IPR018815|refseq:NP_012652.3|mint:P47155|ensemblfungi:YJR118C(gene)|ensemblfungi:YJR118C_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ry0sO64GCCLYt4w5HaTb6IO+1+Y559292 rogid:BrQhbXGvUjNG6Bt5c0J7T8qzMeI559292 intact-crc:A15901A792FB5DD0|rigid:O7p/RfnR8LjBT84rGzo3nJ9fa2I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53045 uniprotkb:P54837 intact:EBI-6506|uniprotkb:D6VUJ5|uniprotkb:Q45U26|uniprotkb:E9P8T3|ensemblfungi:YGR060W intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:msmo_yeast(display_long)|uniprotkb:ERG25(gene name)|psi-mi:ERG25(display_short)|uniprotkb:FET6(gene name synonym)|uniprotkb:C-4 methylsterol oxidase(gene name synonym)|uniprotkb:Sterol-C4-methyl oxidase(gene name synonym)|uniprotkb:YGR060W(locus name) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335951|imex:IM-14275-2002 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003292|refseq:NP_011574.3|mint:P53045|dip:DIP-2799N|ensemblfungi:YGR060W(gene)|ensemblfungi:YGR060W_mRNA(transcript)|go:"GO:0000254"(C-4 methylsterol oxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-SCE-191273|reactome:R-SCE-192105 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ry0sO64GCCLYt4w5HaTb6IO+1+Y559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:B40AAD1F2E1E1327|rigid:OrAXQGXhxxTAI2OWAyvpMk+01Jc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04969 uniprotkb:P53045 intact:EBI-27827|uniprotkb:D6VZB9|ensemblfungi:YML055W intact:EBI-6506|uniprotkb:D6VUJ5|uniprotkb:Q45U26|uniprotkb:E9P8T3|ensemblfungi:YGR060W psi-mi:spc2_yeast(display_long)|uniprotkb:YML055W(locus name)|uniprotkb:YM9958.07(orf name)|uniprotkb:SPC2(gene name)|psi-mi:SPC2(display_short)|uniprotkb:SPY1(gene name synonym)|uniprotkb:Microsomal signal peptidase subunit 2(gene name synonym) psi-mi:msmo_yeast(display_long)|uniprotkb:ERG25(gene name)|psi-mi:ERG25(display_short)|uniprotkb:FET6(gene name synonym)|uniprotkb:C-4 methylsterol oxidase(gene name synonym)|uniprotkb:Sterol-C4-methyl oxidase(gene name synonym)|uniprotkb:YGR060W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335962|imex:IM-14275-2003 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013657.1|sgd:S000004519|dip:DIP-4540N|mint:Q04969|ensemblfungi:YML055W(gene)|ensemblfungi:YML055W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit) sgd:S000003292|refseq:NP_011574.3|mint:P53045|dip:DIP-2799N|ensemblfungi:YGR060W(gene)|ensemblfungi:YGR060W_mRNA(transcript)|go:"GO:0000254"(C-4 methylsterol oxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-SCE-191273|reactome:R-SCE-192105 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZXf9rPA3/ryPnDqI4JGp0VMNMe4559292 rogid:Ry0sO64GCCLYt4w5HaTb6IO+1+Y559292 intact-crc:C6E461CF1813BA1C|rigid:IFndDOklNcsz5B+pGOstIQdnHxA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:P53045 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-6506|uniprotkb:D6VUJ5|uniprotkb:Q45U26|uniprotkb:E9P8T3|ensemblfungi:YGR060W psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:msmo_yeast(display_long)|uniprotkb:ERG25(gene name)|psi-mi:ERG25(display_short)|uniprotkb:FET6(gene name synonym)|uniprotkb:C-4 methylsterol oxidase(gene name synonym)|uniprotkb:Sterol-C4-methyl oxidase(gene name synonym)|uniprotkb:YGR060W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335973|imex:IM-14275-2004 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 sgd:S000003292|refseq:NP_011574.3|mint:P53045|dip:DIP-2799N|ensemblfungi:YGR060W(gene)|ensemblfungi:YGR060W_mRNA(transcript)|go:"GO:0000254"(C-4 methylsterol oxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-SCE-191273|reactome:R-SCE-192105 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:Ry0sO64GCCLYt4w5HaTb6IO+1+Y559292 intact-crc:AE93BBE7840BE491|rigid:TYtWZkohCXF8HTZku/VV98pN+Ro false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06144 uniprotkb:P53045 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W intact:EBI-6506|uniprotkb:D6VUJ5|uniprotkb:Q45U26|uniprotkb:E9P8T3|ensemblfungi:YGR060W psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:msmo_yeast(display_long)|uniprotkb:ERG25(gene name)|psi-mi:ERG25(display_short)|uniprotkb:FET6(gene name synonym)|uniprotkb:C-4 methylsterol oxidase(gene name synonym)|uniprotkb:Sterol-C4-methyl oxidase(gene name synonym)|uniprotkb:YGR060W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335984|imex:IM-14275-2005 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 sgd:S000003292|refseq:NP_011574.3|mint:P53045|dip:DIP-2799N|ensemblfungi:YGR060W(gene)|ensemblfungi:YGR060W_mRNA(transcript)|go:"GO:0000254"(C-4 methylsterol oxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-SCE-191273|reactome:R-SCE-192105 psi-mi:"MI:0469"(intact) crc64:2F474503CAB7C195 - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 rogid:Ry0sO64GCCLYt4w5HaTb6IO+1+Y559292 intact-crc:ED3A30F1E2F8E4E9|rigid:9ebq6TRyNL5Z1Y/KrREKrhtblpI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:P53045 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-6506|uniprotkb:D6VUJ5|uniprotkb:Q45U26|uniprotkb:E9P8T3|ensemblfungi:YGR060W psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:msmo_yeast(display_long)|uniprotkb:ERG25(gene name)|psi-mi:ERG25(display_short)|uniprotkb:FET6(gene name synonym)|uniprotkb:C-4 methylsterol oxidase(gene name synonym)|uniprotkb:Sterol-C4-methyl oxidase(gene name synonym)|uniprotkb:YGR060W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6335995|imex:IM-14275-2006 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 sgd:S000003292|refseq:NP_011574.3|mint:P53045|dip:DIP-2799N|ensemblfungi:YGR060W(gene)|ensemblfungi:YGR060W_mRNA(transcript)|go:"GO:0000254"(C-4 methylsterol oxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-SCE-191273|reactome:R-SCE-192105 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:Ry0sO64GCCLYt4w5HaTb6IO+1+Y559292 intact-crc:CEDFCF40B9B87CF5|rigid:q2BjlwL6+kf8Ld8hJBUaxfM1z1I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53049 uniprotkb:P10823 intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336006|imex:IM-14275-2007 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) - crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:117911C057AEA2F0|rigid:fXVt6fiITSm2IZV4m6GwhILGD04 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53049 uniprotkb:P19807 intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336018|imex:IM-14275-2008 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:39BF06DBAB32119E|rigid:iZtdJ3TlT7AeB7aJHtUlFfHGGpU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53049 uniprotkb:P35735 intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336029|imex:IM-14275-2009 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:F29C12801E3C4505|rigid:KKxSF7T+6KiKnw4thc8zQLqBi94 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53049 uniprotkb:P36027 intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336040|imex:IM-14275-2010 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:F172042A606D33B2|rigid:NalXxOiyj0xW/rNA6KsDuVcT0Qw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38234 uniprotkb:P53049 intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336051|imex:IM-14275-2011 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 intact-crc:13315D09A353A67B|rigid:dFaeCLs6l7pD4F5ASk06hwdFaXQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53049 uniprotkb:P50276 intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336062|imex:IM-14275-2012 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:72C3A30B8D55556E|rigid:Lj9+o6A59B+dw2RxiGgaEUtBdM4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53049 uniprotkb:P53049 intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336073|imex:IM-14275-2013 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 intact-crc:B67CAAAA475697A2|rigid:sH6EF90h9BzHNxSp/FaMMaspZpk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53049 uniprotkb:Q02785 intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336084|imex:IM-14275-2014 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:FC1A91ADAE662E80|rigid:shHQNTZRzBSZnAyHxGSscuJ/fcY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53049 uniprotkb:Q03640 intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336095|imex:IM-14275-2015 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) - crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:B22A948007D679DD|rigid:/1R0ku9Niv3QRNBQugceTDV20ig false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08967 uniprotkb:P53049 intact:EBI-36673|uniprotkb:D6W3E9|ensemblfungi:YPL221W intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W psi-mi:flc1_yeast(display_long)|uniprotkb:FAD transporter 1(gene name synonym)|uniprotkb:FLC1(gene name)|psi-mi:FLC1(display_short)|uniprotkb:TRP-like ion channel protein FLC1(gene name synonym)|uniprotkb:Heme utilization factor 1(gene name synonym)|uniprotkb:Bypass of PAM1 protein 1(gene name synonym)|uniprotkb:HUF1(gene name synonym)|uniprotkb:YPL221W(locus name)|uniprotkb:BOP1(gene name synonym) psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336106|imex:IM-14275-2016 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015103.1|sgd:S000006142|mint:Q08967|dip:DIP-3965N|ensemblfungi:YPL221W(gene)|ensemblfungi:YPL221W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055085"(transmembrane transport)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241 sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:r6CcZGEjxHUk2w0iBUBvnAPaFd4559292 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 intact-crc:45BDCD9ED9D787E1|rigid:18pK25ZUewAxytrpWENYuVh4zLA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53049 uniprotkb:Q12256 intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336117|imex:IM-14275-2017 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 intact-crc:01F687B537E0F2AB|rigid:jvJVCU7iHOZ0O8oz7zNv3rBTVgw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06156 uniprotkb:P53053 intact:EBI-4785|uniprotkb:D6VYR9|ensemblfungi:YLR272C intact:EBI-5002|uniprotkb:D6VV71|ensemblfungi:YGL263W psi-mi:cnd1_yeast(display_long)|uniprotkb:YCS4(gene name)|psi-mi:YCS4(display_short)|uniprotkb:LOC7(gene name synonym)|uniprotkb:YLR272C(locus name)|uniprotkb:L8479.14(orf name)|uniprotkb:XCAP-D2 homolog(gene name synonym) psi-mi:cos12_yeast(display_long)|uniprotkb:COS12(gene name)|psi-mi:COS12(display_short)|uniprotkb:NRC380(orf name)|uniprotkb:YGL263W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336128|imex:IM-14275-2018 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013374.1|sgd:S000004262|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR007673(Non-SMC condensin subunit, XCAP-D2/Cnd1)|interpro:IPR024324|interpro:IPR032682|interpro:IPR026971|mint:Q06156|ensemblfungi:YLR272C(gene)|ensemblfungi:YLR272C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0042393"(histone binding)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0051301"(cell division)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0070058"(tRNA gene clustering)|go:"GO:0070550"(rDNA condensation)|go:"GO:1903342"(negative regulation of meiotic DNA double-strand break formation)|rcsb pdb:6YVU|rcsb pdb:6YVV|reactome:R-SCE-2514853 sgd:S000003232|refseq:NP_011251.1|dip:DIP-5034N|mint:P53053|ensemblfungi:YGL263W(gene)|ensemblfungi:YGL263W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|interpro:IPR001142(Yeast membrane protein DUP) psi-mi:"MI:0469"(intact) - crc64:52F58F4E400CA596 figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oVjaJRRti7wAqG4TerYJJZGMK3o559292 rogid:SqJH5ysFjpteLzoBp61CbATkXt8559292 intact-crc:7A705A0D0CBD840A|rigid:XSC19srTkfJ2GBOP3isl7gtEkOk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40340 uniprotkb:P53068 intact:EBI-19030|uniprotkb:D6VV47|ensemblfungi:YGR270W intact:EBI-2603|uniprotkb:D6VV95|ensemblfungi:YGL240W psi-mi:tbp7_yeast(display_long)|uniprotkb:YGR270W(locus name)|uniprotkb:YTA7(gene name)|psi-mi:YTA7(display_short) psi-mi:apc10_yeast(display_long)|uniprotkb:Destruction of cyclin B protein 1(gene name synonym)|uniprotkb:DOC1(gene name)|psi-mi:DOC1(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:YGL240W(locus name)|uniprotkb:HRC283(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336139|imex:IM-14275-2019 author score:99.36 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011786.1|sgd:S000003502|ensemblfungi:YGR270W(gene)|ensemblfungi:YGR270W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0042393"(histone binding)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:2000219"(positive regulation of invasive growth in response to glucose limitation)|interpro:IPR001487(Bromodomain)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR036427|interpro:IPR041569|dip:DIP-6557N|mint:P40340 refseq:NP_011274.2|sgd:S000003209|dip:DIP-1128N|mint:P53068|ensemblfungi:YGL240W(gene)|ensemblfungi:YGL240W_mRNA(transcript)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0007049"(cell cycle)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031497"(chromatin assembly)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|rcsb pdb:1GQP|reactome:R-SCE-983168 psi-mi:"MI:0469"(intact) crc64:31D1F6F87E62E04F crc64:F3C58B1BB986442D figure legend:tables S3 and S4|author-confidence:99.36|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:bDdTbuEPrFv5TH45tEjuyZLGz/k559292 rogid:6xjJ6a7poipPz2UFOwtEp8HwtUA559292 intact-crc:8931E71F073C85DF|rigid:WW1xdKCmts69DIw34FMesUOveqI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53112 uniprotkb:P33760 intact:EBI-13212|uniprotkb:D6VTZ8|ensemblfungi:YGL153W intact:EBI-13178|uniprotkb:D6W0L8|ensemblfungi:YNL329C psi-mi:pex14_yeast(display_long)|uniprotkb:PEX14(gene name)|psi-mi:PEX14(display_short)|uniprotkb:YGL153W(locus name)|uniprotkb:G1870(orf name)|uniprotkb:Peroxin-14(gene name synonym) psi-mi:pex6_yeast(display_long)|uniprotkb:PEX6(gene name)|psi-mi:PEX6(display_short)|uniprotkb:PAS8(gene name synonym)|uniprotkb:YNL329C(locus name)|uniprotkb:N0310(orf name)|uniprotkb:Peroxin-6(gene name synonym)|uniprotkb:Peroxisome biosynthesis protein PAS8(gene name synonym)|uniprotkb:Peroxisomal assembly protein 8(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336150|imex:IM-14275-2020 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003121|refseq:NP_011362.3|mint:P53112|dip:DIP-1749N|ensemblfungi:YGL153W(gene)|ensemblfungi:YGL153W_mRNA(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:1990415"|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR006785(Peroxisome membrane anchor protein Pex14p, N-terminal)|interpro:IPR025655|interpro:IPR036388|rcsb pdb:1N5Z|rcsb pdb:2V1R|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-9603798 refseq:NP_014070.1|sgd:S000005273|mint:P33760|dip:DIP-2621N|ensemblfungi:YNL329C(gene)|ensemblfungi:YNL329C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0043335"(protein unfolding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417 psi-mi:"MI:0469"(intact) crc64:B714D7DA045E2DCB crc64:736FECB57BBFF8F8 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:eS7O3dwiT/56U30PI8bpJny+kZQ559292 rogid:vonluDQS+We5JMYERfce8BzCIVk559292 intact-crc:0F0D85C5B4C128B0|rigid:IbftoNKfy4bGZyvNByrXYWNKgZg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53112 uniprotkb:P40155 intact:EBI-13212|uniprotkb:D6VTZ8|ensemblfungi:YGL153W intact:EBI-13218|ensemblfungi:YNL214W|uniprotkb:D6W0X6 psi-mi:pex14_yeast(display_long)|uniprotkb:PEX14(gene name)|psi-mi:PEX14(display_short)|uniprotkb:YGL153W(locus name)|uniprotkb:G1870(orf name)|uniprotkb:Peroxin-14(gene name synonym) psi-mi:pex17_yeast(display_long)|uniprotkb:PEX17(gene name)|psi-mi:PEX17(display_short)|uniprotkb:PAS9(gene name synonym)|uniprotkb:YNL214W(locus name)|uniprotkb:N1319(orf name)|uniprotkb:Peroxin-17(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336161|imex:IM-14275-2021 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003121|refseq:NP_011362.3|mint:P53112|dip:DIP-1749N|ensemblfungi:YGL153W(gene)|ensemblfungi:YGL153W_mRNA(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:1990415"|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR006785(Peroxisome membrane anchor protein Pex14p, N-terminal)|interpro:IPR025655|interpro:IPR036388|rcsb pdb:1N5Z|rcsb pdb:2V1R|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-9603798 sgd:S000005158|refseq:NP_014185.1|ensemblfungi:YNL214W(gene)|ensemblfungi:YNL214W_mRNA(transcript)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990415"|go:"GO:1990429"(peroxisomal importomer complex)|mint:P40155|dip:DIP-2474N psi-mi:"MI:0469"(intact) crc64:B714D7DA045E2DCB - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:eS7O3dwiT/56U30PI8bpJny+kZQ559292 rogid:NwAQV8soH7a8K+3MI1/nMgHC2dk559292 intact-crc:35FEB82CD682D99F|rigid:EUkTfPO9qiXK3fGhj6trgvLRNTc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53112 uniprotkb:P53112 intact:EBI-13212|uniprotkb:D6VTZ8|ensemblfungi:YGL153W intact:EBI-13212|uniprotkb:D6VTZ8|ensemblfungi:YGL153W psi-mi:pex14_yeast(display_long)|uniprotkb:PEX14(gene name)|psi-mi:PEX14(display_short)|uniprotkb:YGL153W(locus name)|uniprotkb:G1870(orf name)|uniprotkb:Peroxin-14(gene name synonym) psi-mi:pex14_yeast(display_long)|uniprotkb:PEX14(gene name)|psi-mi:PEX14(display_short)|uniprotkb:YGL153W(locus name)|uniprotkb:G1870(orf name)|uniprotkb:Peroxin-14(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336172|imex:IM-14275-2022 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003121|refseq:NP_011362.3|mint:P53112|dip:DIP-1749N|ensemblfungi:YGL153W(gene)|ensemblfungi:YGL153W_mRNA(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:1990415"|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR006785(Peroxisome membrane anchor protein Pex14p, N-terminal)|interpro:IPR025655|interpro:IPR036388|rcsb pdb:1N5Z|rcsb pdb:2V1R|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-9603798 sgd:S000003121|refseq:NP_011362.3|mint:P53112|dip:DIP-1749N|ensemblfungi:YGL153W(gene)|ensemblfungi:YGL153W_mRNA(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:1990415"|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR006785(Peroxisome membrane anchor protein Pex14p, N-terminal)|interpro:IPR025655|interpro:IPR036388|rcsb pdb:1N5Z|rcsb pdb:2V1R|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-9603798 psi-mi:"MI:0469"(intact) crc64:B714D7DA045E2DCB crc64:B714D7DA045E2DCB figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:eS7O3dwiT/56U30PI8bpJny+kZQ559292 rogid:eS7O3dwiT/56U30PI8bpJny+kZQ559292 intact-crc:97058D478976CF7D|rigid:QAPkvIDsg7CjWPg5N/19QRFvLQo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07418 uniprotkb:P53112 intact:EBI-292|uniprotkb:D6VRT2|ensemblfungi:YDL065C intact:EBI-13212|uniprotkb:D6VTZ8|ensemblfungi:YGL153W psi-mi:pex19_yeast(display_long)|uniprotkb:PEX19(gene name)|psi-mi:PEX19(display_short)|uniprotkb:PAS12(gene name synonym)|uniprotkb:YDL065C(locus name)|uniprotkb:Peroxin-19(gene name synonym)|uniprotkb:D2528(orf name) psi-mi:pex14_yeast(display_long)|uniprotkb:PEX14(gene name)|psi-mi:PEX14(display_short)|uniprotkb:YGL153W(locus name)|uniprotkb:G1870(orf name)|uniprotkb:Peroxin-14(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336183|imex:IM-14275-2023 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010218.2|sgd:S000002223|dip:DIP-1563N|mint:Q07418|ensemblfungi:YDL065C(gene)|ensemblfungi:YDL065C_mRNA(transcript)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0033328"(peroxisome membrane targeting sequence binding)|go:"GO:0045033"(peroxisome inheritance)|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0050821"(protein stabilization)|go:"GO:1990415"|interpro:IPR006708(Pex19 protein)|interpro:IPR038322|reactome:R-SCE-1369062|reactome:R-SCE-9603798 sgd:S000003121|refseq:NP_011362.3|mint:P53112|dip:DIP-1749N|ensemblfungi:YGL153W(gene)|ensemblfungi:YGL153W_mRNA(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:1990415"|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR006785(Peroxisome membrane anchor protein Pex14p, N-terminal)|interpro:IPR025655|interpro:IPR036388|rcsb pdb:1N5Z|rcsb pdb:2V1R|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-9603798 psi-mi:"MI:0469"(intact) crc64:B2FDE24970443D2A crc64:B714D7DA045E2DCB figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:u/Q3DGHpQR712xEWNu1B/m5V72I559292 rogid:eS7O3dwiT/56U30PI8bpJny+kZQ559292 intact-crc:AC9218D25EAC3574|rigid:baQNyJBFsrZf64n0NdEp2RXNY7c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12329 uniprotkb:P53112 intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W intact:EBI-13212|uniprotkb:D6VTZ8|ensemblfungi:YGL153W psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym) psi-mi:pex14_yeast(display_long)|uniprotkb:PEX14(gene name)|psi-mi:PEX14(display_short)|uniprotkb:YGL153W(locus name)|uniprotkb:G1870(orf name)|uniprotkb:Peroxin-14(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336194|imex:IM-14275-2024 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107 sgd:S000003121|refseq:NP_011362.3|mint:P53112|dip:DIP-1749N|ensemblfungi:YGL153W(gene)|ensemblfungi:YGL153W_mRNA(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:1990415"|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR006785(Peroxisome membrane anchor protein Pex14p, N-terminal)|interpro:IPR025655|interpro:IPR036388|rcsb pdb:1N5Z|rcsb pdb:2V1R|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-9603798 psi-mi:"MI:0469"(intact) crc64:DF353A76493E3CE6 crc64:B714D7DA045E2DCB figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292 rogid:eS7O3dwiT/56U30PI8bpJny+kZQ559292 intact-crc:6CD54C06225A3B9B|rigid:mB1vsKn3wyPzPNLhfWHkyv4sG5w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12462 uniprotkb:P53112 intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C intact:EBI-13212|uniprotkb:D6VTZ8|ensemblfungi:YGL153W psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:pex14_yeast(display_long)|uniprotkb:PEX14(gene name)|psi-mi:PEX14(display_short)|uniprotkb:YGL153W(locus name)|uniprotkb:G1870(orf name)|uniprotkb:Peroxin-14(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336205|imex:IM-14275-2025 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) sgd:S000003121|refseq:NP_011362.3|mint:P53112|dip:DIP-1749N|ensemblfungi:YGL153W(gene)|ensemblfungi:YGL153W_mRNA(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:1990415"|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR006785(Peroxisome membrane anchor protein Pex14p, N-terminal)|interpro:IPR025655|interpro:IPR036388|rcsb pdb:1N5Z|rcsb pdb:2V1R|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-9603798 psi-mi:"MI:0469"(intact) - crc64:B714D7DA045E2DCB figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 rogid:eS7O3dwiT/56U30PI8bpJny+kZQ559292 intact-crc:281FC08ECA810375|rigid:h7tX1GWYYqEprRiAEF+5TzOPZy8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33895 uniprotkb:P53119 intact:EBI-12377|uniprotkb:Q6B1X5|ensemblfungi:YOL069W|uniprotkb:D6W1Z8 intact:EBI-8728|ensemblfungi:YGL141W|uniprotkb:D6VU08 psi-mi:nuf2_yeast(display_long)|uniprotkb:YOL069W(locus name)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short) psi-mi:hul5_yeast(display_long)|uniprotkb:HUL5(gene name)|psi-mi:HUL5(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase HUL5(gene name synonym)|uniprotkb:YGL141W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336216|imex:IM-14275-2026 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOL069W(gene)|ensemblfungi:YOL069W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005816"(spindle pole body)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|rcsb pdb:5TCS|rcsb pdb:5TD8|go:"GO:0045132"(meiotic chromosome segregation)|refseq:NP_014572.1|sgd:S000005430|mint:P33895|dip:DIP-1481N interpro:IPR000569(HECT)|interpro:IPR035983|interpro:IPR044611|reactome:R-SCE-983168|ensemblfungi:YGL141W(gene)|ensemblfungi:YGL141W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|refseq:NP_011374.1|sgd:S000003109|mint:P53119|dip:DIP-6349N psi-mi:"MI:0469"(intact) - crc64:8DB832A48A81CD19 figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oof/8nhKWQCx5bp4lvc7f33OO+0559292 rogid:xA0577XA6kjaMCaQH5g0BpaTpjQ559292 intact-crc:5FDB6F388703B80B|rigid:wudRecuN/P2yuhOh7nOzwns+DEA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38996 uniprotkb:P53125 intact:EBI-11776|uniprotkb:Q07034|ensemblfungi:YPL190C|uniprotkb:D6W3H8 intact:EBI-23967|uniprotkb:D6VU16|ensemblfungi:YGL133W psi-mi:nab3_yeast(display_long)|uniprotkb:YPL190C(locus name)|uniprotkb:NAB3(gene name)|psi-mi:NAB3(display_short)|uniprotkb:HMD1(gene name synonym) psi-mi:itc1_yeast(display_long)|uniprotkb:G2842(orf name)|uniprotkb:YGL133W(locus name)|uniprotkb:ITC1(gene name)|psi-mi:ITC1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336227|imex:IM-14275-2027 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036621|rcsb pdb:2KVI|rcsb pdb:2L41|interpro:IPR035979|rcsb pdb:2XNQ|rcsb pdb:2XNR|ensemblfungi:YPL190C(gene)|ensemblfungi:YPL190C_mRNA(transcript)|go:"GO:0001068"(transcription regulatory region RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0030847"(termination of RNA polymerase II transcription, exosome-dependent)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0034472"(snRNA 3'-end processing)|go:"GO:0035649"(Nrd1 complex)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071041"(antisense RNA transcript catabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034167|refseq:NP_015134.1|sgd:S000006111|mint:P38996|dip:DIP-3980N refseq:NP_011382.1|sgd:S000003101|dip:DIP-6737N|mint:P53125|ensemblfungi:YGL133W(gene)|ensemblfungi:YGL133W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006348"|go:"GO:0008623"(CHRAC)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|interpro:IPR013136(WSTF/Acf1/Cbp146)|interpro:IPR018501|interpro:IPR028941 psi-mi:"MI:0469"(intact) crc64:CD6D2C7F24A44993 - figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iVBA824UReQJmvua7xganVlrm9U559292 rogid:srVskYPFnFM0y+W0zkCLwKQ43jU559292 intact-crc:2B0CFA2A9290128E|rigid:U9mIMGrIydTaiIHqOlk+J48HIgk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53125 uniprotkb:P43593 intact:EBI-23967|uniprotkb:D6VU16|ensemblfungi:YGL133W intact:EBI-19852|uniprotkb:D6VTP0|ensemblfungi:YFR010W psi-mi:itc1_yeast(display_long)|uniprotkb:G2842(orf name)|uniprotkb:YGL133W(locus name)|uniprotkb:ITC1(gene name)|psi-mi:ITC1(display_short) psi-mi:ubp6_yeast(display_long)|uniprotkb:UBP6(gene name)|psi-mi:UBP6(display_short)|uniprotkb:Ubiquitin-specific-processing protease 6(gene name synonym)|uniprotkb:Deubiquitinating enzyme 6(gene name synonym)|uniprotkb:Ubiquitin thioesterase 6(gene name synonym)|uniprotkb:YFR010W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336238|imex:IM-14275-2028 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011382.1|sgd:S000003101|dip:DIP-6737N|mint:P53125|ensemblfungi:YGL133W(gene)|ensemblfungi:YGL133W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006348"|go:"GO:0008623"(CHRAC)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|interpro:IPR013136(WSTF/Acf1/Cbp146)|interpro:IPR018501|interpro:IPR028941 refseq:NP_116665.1|sgd:S000001906|ensemblfungi:YFR010W(gene)|ensemblfungi:YFR010W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR000626(Ubiquitin)|interpro:IPR028889|interpro:IPR029071|interpro:IPR038765|interpro:IPR044635|rcsb pdb:1VJV|rcsb pdb:5A5B|rcsb pdb:5MPC|reactome:R-SCE-5689880|dip:DIP-6731N|mint:P43593 psi-mi:"MI:0469"(intact) - crc64:DAE54D1F8AC9960C figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:srVskYPFnFM0y+W0zkCLwKQ43jU559292 rogid:M4HqdW/7V42HuFuSm4y6z4Oz6tg559292 intact-crc:850125ABFD38DDDD|rigid:kv8F23FTvrvENh5gSUBOplBLSr0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03049 uniprotkb:P53125 intact:EBI-35573|uniprotkb:D6VTG0|ensemblfungi:YDR541C intact:EBI-23967|uniprotkb:D6VU16|ensemblfungi:YGL133W psi-mi:yd541_yeast(display_long)|uniprotkb:YDR541C(locus name) psi-mi:itc1_yeast(display_long)|uniprotkb:G2842(orf name)|uniprotkb:YGL133W(locus name)|uniprotkb:ITC1(gene name)|psi-mi:ITC1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336249|imex:IM-14275-2029 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010830.4|sgd:S000002949|mint:Q03049|dip:DIP-5276N|ensemblfungi:YDR541C(gene)|ensemblfungi:YDR541C_mRNA(transcript)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0033721"("aldehyde dehydrogenase (NADP+) activity")|go:"GO:1901426"(response to furfural)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291 refseq:NP_011382.1|sgd:S000003101|dip:DIP-6737N|mint:P53125|ensemblfungi:YGL133W(gene)|ensemblfungi:YGL133W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006348"|go:"GO:0008623"(CHRAC)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|interpro:IPR013136(WSTF/Acf1/Cbp146)|interpro:IPR018501|interpro:IPR028941 psi-mi:"MI:0469"(intact) crc64:B920E3CD32531254 - figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RINBeahEIT2jY77XenTIYB9wnXU559292 rogid:srVskYPFnFM0y+W0zkCLwKQ43jU559292 intact-crc:6219555632F50227|rigid:tT08BgPGe5MlVpbPMR2/rdH3ubE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96VH3 uniprotkb:P53125 intact:EBI-2044941|uniprotkb:D6VQZ3|ensemblfungi:YCL021W-A intact:EBI-23967|uniprotkb:D6VU16|ensemblfungi:YGL133W psi-mi:yc021_yeast(display_long)|uniprotkb:YCL021W-A(locus name) psi-mi:itc1_yeast(display_long)|uniprotkb:G2842(orf name)|uniprotkb:YGL133W(locus name)|uniprotkb:ITC1(gene name)|psi-mi:ITC1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336260|imex:IM-14275-2030 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000007549|refseq:NP_065437.1|mint:Q96VH3|ensemblfungi:YCL021W-A(gene)|ensemblfungi:YCL021W-A_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0016021"(integral component of membrane) refseq:NP_011382.1|sgd:S000003101|dip:DIP-6737N|mint:P53125|ensemblfungi:YGL133W(gene)|ensemblfungi:YGL133W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006348"|go:"GO:0008623"(CHRAC)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|interpro:IPR013136(WSTF/Acf1/Cbp146)|interpro:IPR018501|interpro:IPR028941 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:KPtxCFX4m13AghkJuoOkuTMuIWA559292 rogid:srVskYPFnFM0y+W0zkCLwKQ43jU559292 intact-crc:955EDD7B199E2059|rigid:UQrQH46j/TndKHmaNmP4nG0i2s8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53131 uniprotkb:P07278 intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 intact:EBI-9475|ensemblfungi:YIL033C|uniprotkb:D6VVP9 psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:kapr_yeast(display_long)|uniprotkb:YIL033C(locus name)|uniprotkb:BCY1(gene name)|psi-mi:BCY1(display_short)|uniprotkb:REG1(gene name synonym)|uniprotkb:SRA1(gene name synonym)|uniprotkb:Bypass of cyclase mutations protein 1(gene name synonym)|uniprotkb:Protein kinase A regulatory subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336271|imex:IM-14275-2031 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131 ensemblfungi:YIL033C(gene)|ensemblfungi:YIL033C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0030552"(cAMP binding)|go:"GO:0036278"(positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0061406"(positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|rcsb pdb:3OF1|rcsb pdb:6XQK|refseq:NP_012231.1|sgd:S000001295|mint:P07278|dip:DIP-551N psi-mi:"MI:0469"(intact) crc64:DA8A085EC50FF430 crc64:6D7D97D8E4340AF3 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 rogid:rSJ37UFoFiaHqc/2W5eYNx1qpbg559292 intact-crc:3877B129DAF1C31E|rigid:8U8uhlWBbA9a724dK47ZLdie594 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53131 uniprotkb:P32495 intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 intact:EBI-12014|ensemblfungi:YDL208W|uniprotkb:D6VRE6 psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:nhp2_yeast(display_long)|uniprotkb:NHP2(gene name)|psi-mi:NHP2(display_short)|uniprotkb:YDL208W(locus name)|uniprotkb:D1045(orf name)|uniprotkb:H/ACA snoRNP protein NHP2(gene name synonym)|uniprotkb:High mobility group-like nuclear protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336282|imex:IM-14275-2032 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131 ensemblfungi:YDL208W(gene)|ensemblfungi:YDL208W_mRNA(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000493"(box H/ACA snoRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|rcsb pdb:2LBW|rcsb pdb:2LBX|refseq:NP_010073.2|sgd:S000002367|mint:P32495|dip:DIP-5134N psi-mi:"MI:0469"(intact) crc64:DA8A085EC50FF430 crc64:008188132B494E5D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 rogid:p5AQTuMF3Vvdu6HWSTYjdjjE1Vs559292 intact-crc:F198141EE4DDB887|rigid:KqDa+Gm9MjhjtR4Pun3vV92aPO4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53131 uniprotkb:P53131 intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336293|imex:IM-14275-2033 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131 go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131 psi-mi:"MI:0469"(intact) crc64:DA8A085EC50FF430 crc64:DA8A085EC50FF430 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 intact-crc:B8B3E23665D19ECA|rigid:tNoK4mmA8zKSwb3FtGKcmbI6qMg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03525 uniprotkb:P53131 intact:EBI-27597|uniprotkb:Q7Z870|ensemblfungi:YMR269W|uniprotkb:D6W095 intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 psi-mi:tma23_yeast(display_long)|uniprotkb:YMR269W(locus name)|uniprotkb:YM8156.11(orf name)|uniprotkb:TMA23(gene name)|psi-mi:TMA23(display_short)|uniprotkb:YMR268W-A(orf name)|uniprotkb:23 kDa translation machinery-associated protein(gene name synonym) psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336304|imex:IM-14275-2034 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR269W(gene)|ensemblfungi:YMR269W_mRNA(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0042274"(ribosomal small subunit biogenesis)|sgd:S000004882|refseq:NP_013996.2|dip:DIP-1965N|mint:Q03525 go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131 psi-mi:"MI:0469"(intact) - crc64:DA8A085EC50FF430 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:yJy9JnQUnYKqa7aOQ5yEeHcNEpI559292 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 intact-crc:EF8C163A88BF1AA3|rigid:jdORNPzvT6UojjDaX5J8cZGtohs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53131 uniprotkb:Q6Q547 intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 intact:EBI-2052475|uniprotkb:D3DL22|ensemblfungi:YHR072W-A psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:nop10_yeast(display_long)|uniprotkb:YHR072W-A(locus name)|uniprotkb:Nucleolar protein family A member 3(gene name synonym)|uniprotkb:snoRNP protein NOP10(gene name synonym)|uniprotkb:NOP10(gene name)|psi-mi:NOP10(display_short)|uniprotkb:Nucleolar protein 10(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336315|imex:IM-14275-2035 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131 refseq:NP_058135.1|sgd:S000007455|dip:DIP-5845N|mint:Q6Q547|ensemblfungi:YHR072W-A(gene)|ensemblfungi:YHR072W-A_mRNA(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|interpro:IPR007264(Nucleolar RNA-binding protein Nop10p)|interpro:IPR036756|rcsb pdb:1Y2Y|rcsb pdb:2AQA|rcsb pdb:3U28|rcsb pdb:3UAI psi-mi:"MI:0469"(intact) crc64:DA8A085EC50FF430 crc64:4718D35AF7911FBA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 rogid:9m0x3DatObFwua2cbCQYMRKGqrU559292 intact-crc:C3F5522AE6C2602D|rigid:WDlCVGnuTIf6pQn6oXeyGZ9N5eY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53145 uniprotkb:P38344 intact:EBI-23885|uniprotkb:D6VU46|ensemblfungi:YGL099W intact:EBI-21136|uniprotkb:D6VQR3|ensemblfungi:YBR267W psi-mi:lsg1_yeast(display_long)|uniprotkb:LSG1(gene name)|psi-mi:LSG1(display_short)|uniprotkb:YGL099W(locus name) psi-mi:rei1_yeast(display_long)|uniprotkb:REI1(gene name)|psi-mi:REI1(display_short)|uniprotkb:Required for isotropic bud growth protein 1(gene name synonym)|uniprotkb:pre-60S factor REI1(gene name synonym)|uniprotkb:YBR1736(orf name)|uniprotkb:YBR267W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336326|imex:IM-14275-2036 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003067|refseq:NP_011416.3|dip:DIP-6659N|mint:P53145|ensemblfungi:YGL099W(gene)|ensemblfungi:YGL099W_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0043332"(mating projection tip)|interpro:IPR006073(GTP1/OBG)|interpro:IPR027417|interpro:IPR030378|interpro:IPR043358|rcsb pdb:5T62|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6QIK|rcsb pdb:6QTZ|rcsb pdb:6RI5|rcsb pdb:6RZZ|rcsb pdb:6S05 refseq:NP_009825.4|sgd:S000000471|mint:P38344|dip:DIP-6347N|rcsb pdb:6RZZ|rcsb pdb:5APN|ensemblfungi:YBR267W(gene)|ensemblfungi:YBR267W_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR040025|interpro:IPR041661 psi-mi:"MI:0469"(intact) crc64:15FD76541A2E8410 crc64:D01AA8FFDF4A0BAC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9mANWO3rTsE/zCUr9GL6WxIexMU559292 rogid:YxMyWWxJUH2Pk41X+98x8jcnqhc559292 intact-crc:5D8995790F30D9CB|rigid:zIjuyV+Cj+PZHIxsMCnnJEKBylg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02256 uniprotkb:P53145 intact:EBI-14322|uniprotkb:D6VVV7|ensemblfungi:YIR026C intact:EBI-23885|uniprotkb:D6VU46|ensemblfungi:YGL099W psi-mi:pvh1_yeast(display_long)|uniprotkb:YIR026C(locus name)|uniprotkb:YVH1(gene name)|psi-mi:YVH1(display_short) psi-mi:lsg1_yeast(display_long)|uniprotkb:LSG1(gene name)|psi-mi:LSG1(display_short)|uniprotkb:YGL099W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336337|imex:IM-14275-2037 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YIR026C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|ensemblfungi:YIR026C(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1990275"(preribosome binding)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|sgd:S000001465|interpro:IPR020422|interpro:IPR029021|rcsb pdb:6N8M|interpro:IPR016278(Tyrosine protein phosphatase, dual specificity, 12)|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6RZZ|rcsb pdb:6S05|refseq:NP_012292.3|mint:Q02256|dip:DIP-5192N sgd:S000003067|refseq:NP_011416.3|dip:DIP-6659N|mint:P53145|ensemblfungi:YGL099W(gene)|ensemblfungi:YGL099W_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0043332"(mating projection tip)|interpro:IPR006073(GTP1/OBG)|interpro:IPR027417|interpro:IPR030378|interpro:IPR043358|rcsb pdb:5T62|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6QIK|rcsb pdb:6QTZ|rcsb pdb:6RI5|rcsb pdb:6RZZ|rcsb pdb:6S05 psi-mi:"MI:0469"(intact) crc64:9E75C7CC14353B43 crc64:15FD76541A2E8410 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9C9+S3aubsVjSLE5Kklpws+PA0A559292 rogid:9mANWO3rTsE/zCUr9GL6WxIexMU559292 intact-crc:F2F659D37677E7EC|rigid:jCJhRIYwg6/LUYAZ/bW2vltwXRI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40210 uniprotkb:P53152 intact:EBI-27280|uniprotkb:D6VZW3|ensemblfungi:YMR140W intact:EBI-11035|ensemblfungi:YGL087C|uniprotkb:D6VU57 psi-mi:sip5_yeast(display_long)|uniprotkb:YMR140W(locus name)|uniprotkb:YM9375.09(orf name)|uniprotkb:SIP5(gene name)|psi-mi:SIP5(display_short)|uniprotkb:SNF1-interacting protein 5(gene name synonym) psi-mi:mms2_yeast(display_long)|uniprotkb:MMS2(gene name)|psi-mi:MMS2(display_short)|uniprotkb:YGL087C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336349|imex:IM-14275-2038 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004748|refseq:NP_013860.1|mint:P40210|dip:DIP-4656N|ensemblfungi:YMR140W(gene)|ensemblfungi:YMR140W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0042149"(cellular response to glucose starvation)|interpro:IPR039301 go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006301"(postreplication repair)|ensemblfungi:YGL087C(gene)|ensemblfungi:YGL087C_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0016874"(ligase activity)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0044395"(protein targeting to vacuolar membrane)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:1JAT|rcsb pdb:2GMI|rcsb pdb:5OJW|reactome:R-SCE-8866654|reactome:R-SCE-9020702|reactome:R-SCE-9646399|reactome:R-SCE-983168|sgd:S000003055|refseq:NP_011428.1|mint:P53152|dip:DIP-5829N psi-mi:"MI:0469"(intact) - crc64:E1DA713C94378795 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6WSFQ9V598lJW1o+h2DCP7vRyeA559292 rogid:dthbFT/vOgnFoOeCLfng4kqOXwA559292 intact-crc:AB35FF161472D047|rigid:/KXSCGth19WU0dZEkiNK5Z9YCW4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53152 uniprotkb:P52490 intact:EBI-11035|ensemblfungi:YGL087C|uniprotkb:D6VU57 intact:EBI-19777|uniprotkb:D6VS79|ensemblfungi:YDR092W psi-mi:mms2_yeast(display_long)|uniprotkb:MMS2(gene name)|psi-mi:MMS2(display_short)|uniprotkb:YGL087C(locus name) psi-mi:ubc13_yeast(display_long)|uniprotkb:UBC13(gene name)|psi-mi:UBC13(display_short)|uniprotkb:YDR092W(locus name)|uniprotkb:YD6652.04(orf name)|uniprotkb:Ubiquitin-protein ligase 13(gene name synonym)|uniprotkb:Ubiquitin carrier protein 13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 13(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336360|imex:IM-14275-2039 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006301"(postreplication repair)|ensemblfungi:YGL087C(gene)|ensemblfungi:YGL087C_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0016874"(ligase activity)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0044395"(protein targeting to vacuolar membrane)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:1JAT|rcsb pdb:2GMI|rcsb pdb:5OJW|reactome:R-SCE-8866654|reactome:R-SCE-9020702|reactome:R-SCE-9646399|reactome:R-SCE-983168|sgd:S000003055|refseq:NP_011428.1|mint:P53152|dip:DIP-5829N sgd:S000002499|ensemblfungi:YDR092W(gene)|ensemblfungi:YDR092W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006301"(postreplication repair)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0044395"(protein targeting to vacuolar membrane)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1JAT|rcsb pdb:1JBB|rcsb pdb:2GMI|rcsb pdb:4FH1|rcsb pdb:5OJW|reactome:R-SCE-8866654|reactome:R-SCE-9020702|reactome:R-SCE-9646399|reactome:R-SCE-983168|refseq:NP_010377.3|dip:DIP-5486N|mint:P52490 psi-mi:"MI:0469"(intact) crc64:E1DA713C94378795 crc64:445558F8F193275B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dthbFT/vOgnFoOeCLfng4kqOXwA559292 rogid:5nTtjUZ2IpzHhrj1UU6NlaRW53k559292 intact-crc:A21E993B50829AEE|rigid:2HvOlTQ4q5PxQvQ1MCdFAqHyR3M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53152 uniprotkb:P53751 intact:EBI-11035|ensemblfungi:YGL087C|uniprotkb:D6VU57 intact:EBI-28557|uniprotkb:D6W1P0|ensemblfungi:YNR065C psi-mi:mms2_yeast(display_long)|uniprotkb:MMS2(gene name)|psi-mi:MMS2(display_short)|uniprotkb:YGL087C(locus name) psi-mi:yn94_yeast(display_long)|uniprotkb:N3539(orf name)|uniprotkb:YNR065C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336371|imex:IM-14275-2040 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006301"(postreplication repair)|ensemblfungi:YGL087C(gene)|ensemblfungi:YGL087C_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0016874"(ligase activity)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0044395"(protein targeting to vacuolar membrane)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:1JAT|rcsb pdb:2GMI|rcsb pdb:5OJW|reactome:R-SCE-8866654|reactome:R-SCE-9020702|reactome:R-SCE-9646399|reactome:R-SCE-983168|sgd:S000003055|refseq:NP_011428.1|mint:P53152|dip:DIP-5829N refseq:NP_014463.1|sgd:S000005348|dip:DIP-4251N|mint:P53751|ensemblfungi:YNR065C(gene)|ensemblfungi:YNR065C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778 psi-mi:"MI:0469"(intact) crc64:E1DA713C94378795 crc64:C0361878FE4DAB90 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dthbFT/vOgnFoOeCLfng4kqOXwA559292 rogid:7iodiUQu3ZxDDC4KQlI3CoYD1IE559292 intact-crc:4CD3B59757DCC6A1|rigid:FiENKjDSdhHiTxECy+iHDKxM+Hc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53154 uniprotkb:P38694 intact:EBI-7994|uniprotkb:D6VU60|ensemblfungi:YGL084C intact:EBI-24511|uniprotkb:D3DKY6|ensemblfungi:YHR039C psi-mi:gup1_yeast(display_long)|uniprotkb:GUP1(gene name)|psi-mi:GUP1(display_short)|uniprotkb:Glycerol uptake protein 1(gene name synonym)|uniprotkb:YGL084C(locus name) psi-mi:msc7_yeast(display_long)|uniprotkb:MSC7(gene name)|psi-mi:MSC7(display_short)|uniprotkb:Meiotic sister-chromatid recombination protein 7(gene name synonym)|uniprotkb:YHR039C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336382|imex:IM-14275-2041 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011431.1|sgd:S000003052|mint:P53154|dip:DIP-4367N|ensemblfungi:YGL084C(gene)|ensemblfungi:YGL084C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0015793"(glycerol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR004299(Membrane bound O-acyl transferase, MBOAT) refseq:NP_011904.1|sgd:S000001081|dip:DIP-1878N|mint:P38694|ensemblfungi:YHR039C(gene)|ensemblfungi:YHR039C_mRNA(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007131"(reciprocal meiotic recombination)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0GR58nPxQE4/TkHbL+KlHyGXsaw559292 rogid:p2xtb6/xYI/jfPNtO6JRZs+5t6I559292 intact-crc:5FD0C2543F546865|rigid:1EPEKdQUOj7sl0pmFSnq+KlzFSc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53166 uniprotkb:Q04049 intact:EBI-23808|uniprotkb:D6VU77|ensemblfungi:YGL064C intact:EBI-36214|uniprotkb:D6VT49|ensemblfungi:YDR419W psi-mi:mrh4_yeast(display_long)|uniprotkb:YGL064C(locus name)|uniprotkb:MRH4(gene name)|psi-mi:MRH4(display_short)|uniprotkb:Mitochondrial RNA helicase 4(gene name synonym) psi-mi:polh_yeast(display_long)|uniprotkb:RAD30(gene name)|psi-mi:RAD30(display_short)|uniprotkb:DBH1(gene name synonym)|uniprotkb:YDR419W(locus name)|uniprotkb:Radiation-sensitive protein 30(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336393|imex:IM-14275-2042 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011451.1|sgd:S000003032|dip:DIP-6672N|mint:P53166|ensemblfungi:YGL064C(gene)|ensemblfungi:YGL064C_mRNA(transcript)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006364"(rRNA processing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902775"(mitochondrial large ribosomal subunit assembly)|go:"GO:1990400"(mitochondrial ribosomal large subunit rRNA binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417 sgd:S000002827|refseq:NP_010707.3|mint:Q04049|dip:DIP-6500N|ensemblfungi:YDR419W(gene)|ensemblfungi:YDR419W_mRNA(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0070987"(error-free translesion synthesis)|interpro:IPR001126(UMUC-like DNA-repair protein)|interpro:IPR036775|interpro:IPR041298|interpro:IPR043128|interpro:IPR043502|rcsb pdb:1JIH|rcsb pdb:2R8J|rcsb pdb:2R8K|rcsb pdb:2WTF|rcsb pdb:2XGP|rcsb pdb:2XGQ|rcsb pdb:3MFH|rcsb pdb:3MFI|rcsb pdb:3OHA|rcsb pdb:3OHB|rcsb pdb:5VTP|reactome:R-SCE-110320|reactome:R-SCE-5656169 psi-mi:"MI:0469"(intact) - crc64:CFB1A9FBC8AFE39B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mwc3172Pu5XDMf45gFfjzWb0Eh0559292 rogid:UezH5s3d7XqG3y3LEglWvRzgzCc559292 intact-crc:D2ADD0A5C8BBBE79|rigid:rqgDfuT/UG23ADsOr7v46Dq7wXs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26364 uniprotkb:P53168 intact:EBI-9452|ensemblfungi:YER170W|uniprotkb:D3DM78 intact:EBI-23800|uniprotkb:D6VU80|ensemblfungi:YGL061C psi-mi:kad3_yeast(display_long)|uniprotkb:YER170W(locus name)|uniprotkb:ADK2(gene name)|psi-mi:ADK2(display_short)|uniprotkb:PAK3(gene name synonym)|uniprotkb:AKY3(gene name synonym)|uniprotkb:Adenylate kinase 3(gene name synonym) psi-mi:duo1_yeast(display_long)|uniprotkb:YGL061C(locus name)|uniprotkb:DUO1(gene name)|psi-mi:DUO1(display_short)|uniprotkb:Outer kinetochore protein DUO1(gene name synonym)|uniprotkb:Death upon overproduction protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336404|imex:IM-14275-2043 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER170W(gene)|ensemblfungi:YER170W_mRNA(transcript)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006172"(ADP biosynthetic process)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046041"(ITP metabolic process)|go:"GO:0046899"(nucleoside triphosphate adenylate kinase activity)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006259(Adenylate kinase, subfamily)|interpro:IPR007862(Adenylate kinase, zinc-finger lid region)|interpro:IPR027417|interpro:IPR028586|interpro:IPR033690|reactome:R-SCE-499943|reactome:R-SCE-983231|refseq:NP_011097.3|sgd:S000000972|mint:P26364|dip:DIP-4877N refseq:NP_011454.1|sgd:S000003029|dip:DIP-1287N|mint:P53168|ensemblfungi:YGL061C(gene)|ensemblfungi:YGL061C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0042729"(DASH complex)|go:"GO:0051301"(cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|interpro:IPR013960(DASH complex, subunit Duo1) psi-mi:"MI:0469"(intact) - crc64:787F8AF869E3C978 figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:m0IaAO9guekG2EgX0mkzONObzvM559292 rogid:uD838V20+p0YnjGgph8EZsT8/VE559292 intact-crc:E12BB831BEA62987|rigid:WR5Qf2DzH+mdP4zCm3XUFlE984c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:P53172 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-23782|uniprotkb:Q6B1R7|uniprotkb:D6VU85|ensemblfungi:YGL056C psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:sds23_yeast(display_long)|uniprotkb:YGL056C(locus name)|uniprotkb:SDS23(gene name)|psi-mi:SDS23(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336415|imex:IM-14275-2044 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) refseq:NP_011459.2|sgd:S000003024|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR016711(Sds23)|mint:P53172|ensemblfungi:YGL056C(gene)|ensemblfungi:YGL056C_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0006468"(protein phosphorylation) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:6VGrwfOKeYCHY2s0s76ChYzLI4M559292 intact-crc:280DD6248BC438D2|rigid:9PwLNPOBak4yjwNxjWdEq7DSGQ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53172 uniprotkb:P32465 intact:EBI-23782|uniprotkb:Q6B1R7|uniprotkb:D6VU85|ensemblfungi:YGL056C intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 psi-mi:sds23_yeast(display_long)|uniprotkb:YGL056C(locus name)|uniprotkb:SDS23(gene name)|psi-mi:SDS23(display_short) psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336426|imex:IM-14275-2045 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011459.2|sgd:S000003024|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR016711(Sds23)|mint:P53172|ensemblfungi:YGL056C(gene)|ensemblfungi:YGL056C_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0006468"(protein phosphorylation) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6VGrwfOKeYCHY2s0s76ChYzLI4M559292 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 intact-crc:3302ED58288F2B08|rigid:AXEg2btw9I9hUJVFEp5KNocSysM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53172 uniprotkb:P32568 intact:EBI-23782|uniprotkb:Q6B1R7|uniprotkb:D6VU85|ensemblfungi:YGL056C intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W psi-mi:sds23_yeast(display_long)|uniprotkb:YGL056C(locus name)|uniprotkb:SDS23(gene name)|psi-mi:SDS23(display_short) psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336437|imex:IM-14275-2046 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011459.2|sgd:S000003024|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR016711(Sds23)|mint:P53172|ensemblfungi:YGL056C(gene)|ensemblfungi:YGL056C_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0006468"(protein phosphorylation) refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6VGrwfOKeYCHY2s0s76ChYzLI4M559292 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 intact-crc:F0ED8EBB8BD8AD2B|rigid:sw5m8K8lylgxMVJdnPPeXrYcqpI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53172 uniprotkb:P33302 intact:EBI-23782|uniprotkb:Q6B1R7|uniprotkb:D6VU85|ensemblfungi:YGL056C intact:EBI-13038|uniprotkb:D6W2L0|ensemblfungi:YOR153W psi-mi:sds23_yeast(display_long)|uniprotkb:YGL056C(locus name)|uniprotkb:SDS23(gene name)|psi-mi:SDS23(display_short) psi-mi:pdr5_yeast(display_long)|uniprotkb:PDR5(gene name)|psi-mi:PDR5(display_short)|uniprotkb:LEM1(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 5(gene name synonym)|uniprotkb:Suppressor of toxicity of sporidesmin(gene name synonym)|uniprotkb:YOR153W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336448|imex:IM-14275-2047 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011459.2|sgd:S000003024|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR016711(Sds23)|mint:P53172|ensemblfungi:YGL056C(gene)|ensemblfungi:YGL056C_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0006468"(protein phosphorylation) sgd:S000005679|refseq:NP_014796.3|mint:P33302|dip:DIP-6776N|ensemblfungi:YOR153W(gene)|ensemblfungi:YOR153W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR029481|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6VGrwfOKeYCHY2s0s76ChYzLI4M559292 rogid:Sd6SJWf6B0rDZnLVaPHyvr4lhew559292 intact-crc:123625260173C146|rigid:pZR2iZ8EaGAzrwgUEPtprKHCGhQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33413 uniprotkb:P53172 intact:EBI-2060312|uniprotkb:D3DKP5|ensemblfungi:YHL016C intact:EBI-23782|uniprotkb:Q6B1R7|uniprotkb:D6VU85|ensemblfungi:YGL056C psi-mi:dur3_yeast(display_long)|uniprotkb:DUR3(gene name)|psi-mi:DUR3(display_short)|uniprotkb:YHL016C(locus name) psi-mi:sds23_yeast(display_long)|uniprotkb:YGL056C(locus name)|uniprotkb:SDS23(gene name)|psi-mi:SDS23(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336459|imex:IM-14275-2048 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031155|refseq:NP_011847.1|sgd:S000001008|interpro:IPR001734(Na+/solute symporter)|interpro:IPR038377|mint:P33413|ensemblfungi:YHL016C(gene)|ensemblfungi:YHL016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0015204"(urea transmembrane transporter activity)|go:"GO:0015489"(putrescine transmembrane transporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015840"(urea transport)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery) refseq:NP_011459.2|sgd:S000003024|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR016711(Sds23)|mint:P53172|ensemblfungi:YGL056C(gene)|ensemblfungi:YGL056C_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0006468"(protein phosphorylation) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oTFsdtOngA3q5wCbhK/fpVlIsz0559292 rogid:6VGrwfOKeYCHY2s0s76ChYzLI4M559292 intact-crc:C4D68142B8A812F0|rigid:XhoCdDkrlsFQLVPefe3TIjncZj0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53172 uniprotkb:P33892 intact:EBI-23782|uniprotkb:Q6B1R7|uniprotkb:D6VU85|ensemblfungi:YGL056C intact:EBI-7442|uniprotkb:D6VTV8|ensemblfungi:YGL195W psi-mi:sds23_yeast(display_long)|uniprotkb:YGL056C(locus name)|uniprotkb:SDS23(gene name)|psi-mi:SDS23(display_short) psi-mi:gcn1_yeast(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:General control non-derepressible protein 1(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym)|uniprotkb:G1318(orf name)|uniprotkb:YGL195W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336470|imex:IM-14275-2049 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011459.2|sgd:S000003024|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR016711(Sds23)|mint:P53172|ensemblfungi:YGL056C(gene)|ensemblfungi:YGL056C_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0006468"(protein phosphorylation) sgd:S000003163|refseq:NP_011320.3|mint:P33892|dip:DIP-2344N|ensemblfungi:YGL195W(gene)|ensemblfungi:YGL195W_mRNA(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071264"(positive regulation of translational initiation in response to starvation)|go:"GO:0072755"(cellular response to benomyl)|go:"GO:0140469"(GCN2-mediated signaling)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1990451"(cellular stress response to acidic pH)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR022716|interpro:IPR033173|interpro:IPR034085 psi-mi:"MI:0469"(intact) - crc64:980FDD03753E9D1C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6VGrwfOKeYCHY2s0s76ChYzLI4M559292 rogid:WPYtEB/xjy4g2cJFwhe+2teVYVk559292 intact-crc:32158E26200D585A|rigid:CsZumtZsKpwQGemKE1uR6zVtgc4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53172 uniprotkb:P35735 intact:EBI-23782|uniprotkb:Q6B1R7|uniprotkb:D6VU85|ensemblfungi:YGL056C intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:sds23_yeast(display_long)|uniprotkb:YGL056C(locus name)|uniprotkb:SDS23(gene name)|psi-mi:SDS23(display_short) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336481|imex:IM-14275-2050 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011459.2|sgd:S000003024|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR016711(Sds23)|mint:P53172|ensemblfungi:YGL056C(gene)|ensemblfungi:YGL056C_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0006468"(protein phosphorylation) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6VGrwfOKeYCHY2s0s76ChYzLI4M559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:E323411F3ECA6C49|rigid:B6ajxqXlusUEfpPZDViWzgxVmJc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:P53172 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-23782|uniprotkb:Q6B1R7|uniprotkb:D6VU85|ensemblfungi:YGL056C psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:sds23_yeast(display_long)|uniprotkb:YGL056C(locus name)|uniprotkb:SDS23(gene name)|psi-mi:SDS23(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336492|imex:IM-14275-2051 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N refseq:NP_011459.2|sgd:S000003024|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR016711(Sds23)|mint:P53172|ensemblfungi:YGL056C(gene)|ensemblfungi:YGL056C_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0006468"(protein phosphorylation) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:6VGrwfOKeYCHY2s0s76ChYzLI4M559292 intact-crc:E0C0D4D5409B1AFE|rigid:SC6oDWacuYIgaaaLJbZenKCJb1Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53172 uniprotkb:P38234 intact:EBI-23782|uniprotkb:Q6B1R7|uniprotkb:D6VU85|ensemblfungi:YGL056C intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C psi-mi:sds23_yeast(display_long)|uniprotkb:YGL056C(locus name)|uniprotkb:SDS23(gene name)|psi-mi:SDS23(display_short) psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336503|imex:IM-14275-2052 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011459.2|sgd:S000003024|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR016711(Sds23)|mint:P53172|ensemblfungi:YGL056C(gene)|ensemblfungi:YGL056C_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0006468"(protein phosphorylation) refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6VGrwfOKeYCHY2s0s76ChYzLI4M559292 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 intact-crc:02823DF683A58F37|rigid:E0nrxlY5V48QXA3GsJv8M9u5ipI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53172 uniprotkb:P40474 intact:EBI-23782|uniprotkb:Q6B1R7|uniprotkb:D6VU85|ensemblfungi:YGL056C intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W psi-mi:sds23_yeast(display_long)|uniprotkb:YGL056C(locus name)|uniprotkb:SDS23(gene name)|psi-mi:SDS23(display_short) psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336514|imex:IM-14275-2053 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011459.2|sgd:S000003024|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR016711(Sds23)|mint:P53172|ensemblfungi:YGL056C(gene)|ensemblfungi:YGL056C_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0006468"(protein phosphorylation) refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6VGrwfOKeYCHY2s0s76ChYzLI4M559292 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 intact-crc:E8AFCB12B64BC3B7|rigid:C6YTySMGx2sUfqjPv48R72JoMbA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P53172 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-23782|uniprotkb:Q6B1R7|uniprotkb:D6VU85|ensemblfungi:YGL056C psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:sds23_yeast(display_long)|uniprotkb:YGL056C(locus name)|uniprotkb:SDS23(gene name)|psi-mi:SDS23(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336525|imex:IM-14275-2054 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_011459.2|sgd:S000003024|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR016711(Sds23)|mint:P53172|ensemblfungi:YGL056C(gene)|ensemblfungi:YGL056C_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0006468"(protein phosphorylation) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:6VGrwfOKeYCHY2s0s76ChYzLI4M559292 intact-crc:637173F4ADA37C22|rigid:7euIG1p3Hk10pltUFT8RGJcN484 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53388 uniprotkb:P53172 intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W intact:EBI-23782|uniprotkb:Q6B1R7|uniprotkb:D6VU85|ensemblfungi:YGL056C psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:sds23_yeast(display_long)|uniprotkb:YGL056C(locus name)|uniprotkb:SDS23(gene name)|psi-mi:SDS23(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336536|imex:IM-14275-2055 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) refseq:NP_011459.2|sgd:S000003024|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR016711(Sds23)|mint:P53172|ensemblfungi:YGL056C(gene)|ensemblfungi:YGL056C_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0006468"(protein phosphorylation) psi-mi:"MI:0469"(intact) crc64:488A382656039D0B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 rogid:6VGrwfOKeYCHY2s0s76ChYzLI4M559292 intact-crc:43F90C1AF7F58966|rigid:TgpQ9tTcwNPVyVtvjNXJe5o6xRU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02785 uniprotkb:P53172 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C intact:EBI-23782|uniprotkb:Q6B1R7|uniprotkb:D6VU85|ensemblfungi:YGL056C psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:sds23_yeast(display_long)|uniprotkb:YGL056C(locus name)|uniprotkb:SDS23(gene name)|psi-mi:SDS23(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336547|imex:IM-14275-2056 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) refseq:NP_011459.2|sgd:S000003024|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR016711(Sds23)|mint:P53172|ensemblfungi:YGL056C(gene)|ensemblfungi:YGL056C_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0006468"(protein phosphorylation) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 rogid:6VGrwfOKeYCHY2s0s76ChYzLI4M559292 intact-crc:8856F0858FE37387|rigid:qHD+vMiwnD3tdojIihmSkwD3fSk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53172 uniprotkb:Q03640 intact:EBI-23782|uniprotkb:Q6B1R7|uniprotkb:D6VU85|ensemblfungi:YGL056C intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:sds23_yeast(display_long)|uniprotkb:YGL056C(locus name)|uniprotkb:SDS23(gene name)|psi-mi:SDS23(display_short) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336558|imex:IM-14275-2057 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011459.2|sgd:S000003024|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR016711(Sds23)|mint:P53172|ensemblfungi:YGL056C(gene)|ensemblfungi:YGL056C_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0006468"(protein phosphorylation) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) - crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6VGrwfOKeYCHY2s0s76ChYzLI4M559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:C666F5A8265324DA|rigid:1n+gF5FwKQQ7HL3zgIlsySK0jJg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53172 uniprotkb:Q06451 intact:EBI-23782|uniprotkb:Q6B1R7|uniprotkb:D6VU85|ensemblfungi:YGL056C intact:EBI-34275|uniprotkb:D6W4F2|ensemblfungi:YPR156C psi-mi:sds23_yeast(display_long)|uniprotkb:YGL056C(locus name)|uniprotkb:SDS23(gene name)|psi-mi:SDS23(display_short) psi-mi:tpo3_yeast(display_long)|uniprotkb:TPO3(gene name)|psi-mi:TPO3(display_short)|uniprotkb:P9584.7(orf name)|uniprotkb:YPR156C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336569|imex:IM-14275-2058 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011459.2|sgd:S000003024|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR016711(Sds23)|mint:P53172|ensemblfungi:YGL056C(gene)|ensemblfungi:YGL056C_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0006468"(protein phosphorylation) refseq:NP_015482.1|sgd:S000006360|mint:Q06451|dip:DIP-3907N|ensemblfungi:YPR156C(gene)|ensemblfungi:YPR156C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - crc64:D260ED161F800502 figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6VGrwfOKeYCHY2s0s76ChYzLI4M559292 rogid:oVpx7Bjk/mK2Q7+/j05tX3gHw7k559292 intact-crc:E7679FB66EE97B8A|rigid:+geQyT+5rbJkwRaHu1QXZiX6I6g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53172 uniprotkb:Q06689 intact:EBI-23782|uniprotkb:Q6B1R7|uniprotkb:D6VU85|ensemblfungi:YGL056C intact:EBI-38659|uniprotkb:D6VZ50|ensemblfungi:YLR413W psi-mi:sds23_yeast(display_long)|uniprotkb:YGL056C(locus name)|uniprotkb:SDS23(gene name)|psi-mi:SDS23(display_short) psi-mi:yl413_yeast(display_long)|uniprotkb:YLR413W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336580|imex:IM-14275-2059 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011459.2|sgd:S000003024|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR016711(Sds23)|mint:P53172|ensemblfungi:YGL056C(gene)|ensemblfungi:YGL056C_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0006468"(protein phosphorylation) refseq:NP_013517.1|sgd:S000004405|mint:Q06689|dip:DIP-5075N|ensemblfungi:YLR413W(gene)|ensemblfungi:YLR413W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0071944"(cell periphery)|interpro:IPR009571(SUR7) psi-mi:"MI:0469"(intact) - crc64:92E23436DC857E95 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6VGrwfOKeYCHY2s0s76ChYzLI4M559292 rogid:AoTGKjLhw0NECrtuftZqLANonds559292 intact-crc:1AD69D3BD89A4510|rigid:sbo/bv4mJMeYyXSWAhNcirHFDPU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3E756 uniprotkb:P53172 intact:EBI-2044812|uniprotkb:D6VPX0|ensemblfungi:YBL029C-A intact:EBI-23782|uniprotkb:Q6B1R7|uniprotkb:D6VU85|ensemblfungi:YGL056C psi-mi:yb029_yeast(display_long)|uniprotkb:YBL029C-A(locus name) psi-mi:sds23_yeast(display_long)|uniprotkb:YGL056C(locus name)|uniprotkb:SDS23(gene name)|psi-mi:SDS23(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336591|imex:IM-14275-2060 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000007591|refseq:NP_076874.1|mint:Q3E756|ensemblfungi:YBL029C-A(gene)|ensemblfungi:YBL029C-A_mRNA(transcript)|go:"GO:0005886"(plasma membrane) refseq:NP_011459.2|sgd:S000003024|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR016711(Sds23)|mint:P53172|ensemblfungi:YGL056C(gene)|ensemblfungi:YGL056C_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0006468"(protein phosphorylation) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Y9LDkESr65DK5SLFNTw1dBKeqPc559292 rogid:6VGrwfOKeYCHY2s0s76ChYzLI4M559292 intact-crc:EE6C4F3973E3121E|rigid:tsn1z4ri7pQ8250TLVmMEoA3D2Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39968 uniprotkb:P53191 intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W intact:EBI-13400|uniprotkb:E9P8Z2|uniprotkb:D6VUB4|ensemblfungi:YGL023C psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name) psi-mi:pib2_yeast(display_long)|uniprotkb:PIB2(gene name)|psi-mi:PIB2(display_short)|uniprotkb:YGL023C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336602|imex:IM-14275-2061 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N refseq:NP_011492.3|sgd:S000002991|ensemblfungi:YGL023C(gene)|ensemblfungi:YGL023C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|mint:P53191|dip:DIP-6378N psi-mi:"MI:0469"(intact) crc64:B2E75774B47E5933 crc64:512E9B873E6E0164 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292 rogid:3T1+dWkNV7dfKQf0/9hJkjQbRW4559292 intact-crc:18258AA90000E2E7|rigid:Du7EcjtwMCATbARyQz5UyygTVFY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02205 uniprotkb:P53191 intact:EBI-27062|uniprotkb:D6VX73|ensemblfungi:YKR007W intact:EBI-13400|uniprotkb:E9P8Z2|uniprotkb:D6VUB4|ensemblfungi:YGL023C psi-mi:meh1_yeast(display_long)|uniprotkb:GSE complex subunit 2(gene name synonym)|uniprotkb:EGO complex subunit 1(gene name synonym)|uniprotkb:YKR007W(locus name)|uniprotkb:YK106(orf name)|uniprotkb:MEH1(gene name)|psi-mi:MEH1(display_short)|uniprotkb:EGO1(gene name synonym)|uniprotkb:GSE2(gene name synonym) psi-mi:pib2_yeast(display_long)|uniprotkb:PIB2(gene name)|psi-mi:PIB2(display_short)|uniprotkb:YGL023C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336613|imex:IM-14275-2062 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001715|refseq:NP_012932.1|mint:Q02205|dip:DIP-1922N|ensemblfungi:YKR007W(gene)|ensemblfungi:YKR007W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0005829"(cytosol)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007040"(lysosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR028209|rcsb pdb:4XPM|rcsb pdb:6JWP refseq:NP_011492.3|sgd:S000002991|ensemblfungi:YGL023C(gene)|ensemblfungi:YGL023C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|mint:P53191|dip:DIP-6378N psi-mi:"MI:0469"(intact) crc64:995DD1E68331D050 crc64:512E9B873E6E0164 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:73a6e5W5wQixGg2aGXDo4A6NR2s559292 rogid:3T1+dWkNV7dfKQf0/9hJkjQbRW4559292 intact-crc:9BF1198C609C1205|rigid:NW9noXkcLxK96+F6rQNkhlwlT6s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:P53198 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-2058104|uniprotkb:D6VUD6|uniprotkb:E9P916|ensemblfungi:YGL002W psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:erp6_yeast(display_long)|uniprotkb:ERP6(gene name)|psi-mi:ERP6(display_short)|uniprotkb:YGL002W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336624|imex:IM-14275-2063 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_011513.1|sgd:S000002970|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:P53198|ensemblfungi:YGL002W(gene)|ensemblfungi:YGL002W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:pM23btPgVfhIqmxeV0jxQGSX4/8559292 intact-crc:0E08CC2CBEEAC63F|rigid:EhiB05hecFWey8tfZ9/ahAgJEQI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53198 uniprotkb:Q12450 intact:EBI-2058104|uniprotkb:D6VUD6|uniprotkb:E9P916|ensemblfungi:YGL002W intact:EBI-6598|uniprotkb:D6W282|ensemblfungi:YOR016C psi-mi:erp6_yeast(display_long)|uniprotkb:ERP6(gene name)|psi-mi:ERP6(display_short)|uniprotkb:YGL002W(locus name) psi-mi:erp4_yeast(display_long)|uniprotkb:ERP4(gene name)|psi-mi:ERP4(display_short)|uniprotkb:YOR016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336635|imex:IM-14275-2064 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011513.1|sgd:S000002970|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:P53198|ensemblfungi:YGL002W(gene)|ensemblfungi:YGL002W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|reactome:R-SCE-6811434 refseq:NP_014659.1|sgd:S000005542|mint:Q12450|dip:DIP-7868N|ensemblfungi:YOR016C(gene)|ensemblfungi:YOR016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pM23btPgVfhIqmxeV0jxQGSX4/8559292 rogid:An7as6LjEDUYrLvEbua3xSL6bEk559292 intact-crc:25851DF35FD39D68|rigid:GI/i+niuRzSysqtG2Boab+Y30L0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53199 uniprotkb:P54837 intact:EBI-6514|uniprotkb:D6VUD7|ensemblfungi:YGL001C intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:erg26_yeast(display_long)|uniprotkb:ERG26(gene name)|psi-mi:ERG26(display_short)|uniprotkb:C-3 sterol dehydrogenase(gene name synonym)|uniprotkb:C-4 decarboxylase(gene name synonym)|uniprotkb:"NAD(P)-dependent cholesterol dehydrogenase"(gene name synonym)|uniprotkb:YGL001C(locus name) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336646|imex:IM-14275-2065 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011514.1|sgd:S000002969|mint:P53199|dip:DIP-6786N|ensemblfungi:YGL001C(gene)|ensemblfungi:YGL001C_mRNA(transcript)|go:"GO:0000252"("C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity")|go:"GO:0003854"(3-beta-hydroxy-delta5-steroid dehydrogenase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0047012"("sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity")|go:"GO:0102175"(3-beta-hydroxysteroid dehydrogenase/C4-decarboxylase activity)|go:"GO:0103066"("4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity")|go:"GO:0103067"("4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity")|interpro:IPR002225(3-beta hydroxysteroid dehydrogenase/isomerase)|interpro:IPR036291|reactome:R-SCE-191273|reactome:R-SCE-193048|reactome:R-SCE-193368|reactome:R-SCE-193775|reactome:R-SCE-193807|reactome:R-SCE-193993|reactome:R-SCE-194002 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:87CA8FF8D64B0327 - figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZN+ISnTNhtZIkk6fhxo0Sg0xErs559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:0F0A1EF803935E7D|rigid:z/Kw+hT6E7398rOesl5ijAKrYeE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:P53199 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-6514|uniprotkb:D6VUD7|ensemblfungi:YGL001C psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:erg26_yeast(display_long)|uniprotkb:ERG26(gene name)|psi-mi:ERG26(display_short)|uniprotkb:C-3 sterol dehydrogenase(gene name synonym)|uniprotkb:C-4 decarboxylase(gene name synonym)|uniprotkb:"NAD(P)-dependent cholesterol dehydrogenase"(gene name synonym)|uniprotkb:YGL001C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336657|imex:IM-14275-2066 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_011514.1|sgd:S000002969|mint:P53199|dip:DIP-6786N|ensemblfungi:YGL001C(gene)|ensemblfungi:YGL001C_mRNA(transcript)|go:"GO:0000252"("C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity")|go:"GO:0003854"(3-beta-hydroxy-delta5-steroid dehydrogenase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0047012"("sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity")|go:"GO:0102175"(3-beta-hydroxysteroid dehydrogenase/C4-decarboxylase activity)|go:"GO:0103066"("4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity")|go:"GO:0103067"("4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity")|interpro:IPR002225(3-beta hydroxysteroid dehydrogenase/isomerase)|interpro:IPR036291|reactome:R-SCE-191273|reactome:R-SCE-193048|reactome:R-SCE-193368|reactome:R-SCE-193775|reactome:R-SCE-193807|reactome:R-SCE-193993|reactome:R-SCE-194002 psi-mi:"MI:0469"(intact) - crc64:87CA8FF8D64B0327 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:ZN+ISnTNhtZIkk6fhxo0Sg0xErs559292 intact-crc:1591D800A986A9CB|rigid:gacvt48l50LyM4dQL5gjVX9HjFk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06144 uniprotkb:P53199 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W intact:EBI-6514|uniprotkb:D6VUD7|ensemblfungi:YGL001C psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:erg26_yeast(display_long)|uniprotkb:ERG26(gene name)|psi-mi:ERG26(display_short)|uniprotkb:C-3 sterol dehydrogenase(gene name synonym)|uniprotkb:C-4 decarboxylase(gene name synonym)|uniprotkb:"NAD(P)-dependent cholesterol dehydrogenase"(gene name synonym)|uniprotkb:YGL001C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336668|imex:IM-14275-2067 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 refseq:NP_011514.1|sgd:S000002969|mint:P53199|dip:DIP-6786N|ensemblfungi:YGL001C(gene)|ensemblfungi:YGL001C_mRNA(transcript)|go:"GO:0000252"("C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity")|go:"GO:0003854"(3-beta-hydroxy-delta5-steroid dehydrogenase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0047012"("sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity")|go:"GO:0102175"(3-beta-hydroxysteroid dehydrogenase/C4-decarboxylase activity)|go:"GO:0103066"("4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity")|go:"GO:0103067"("4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity")|interpro:IPR002225(3-beta hydroxysteroid dehydrogenase/isomerase)|interpro:IPR036291|reactome:R-SCE-191273|reactome:R-SCE-193048|reactome:R-SCE-193368|reactome:R-SCE-193775|reactome:R-SCE-193807|reactome:R-SCE-193993|reactome:R-SCE-194002 psi-mi:"MI:0469"(intact) crc64:2F474503CAB7C195 crc64:87CA8FF8D64B0327 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 rogid:ZN+ISnTNhtZIkk6fhxo0Sg0xErs559292 intact-crc:56385316CF75A9B3|rigid:CqmmeH8chud4sL3vMub3Lm1OhAc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53223 uniprotkb:P38242 intact:EBI-23136|uniprotkb:D6VUH3|uniprotkb:Q45U47|ensemblfungi:YGR036C intact:EBI-21477|uniprotkb:D6VQ69|ensemblfungi:YBR070C psi-mi:cax4_yeast(display_long)|uniprotkb:CAX4(gene name)|psi-mi:CAX4(display_short)|uniprotkb:CWH8(gene name synonym)|uniprotkb:Dolichyl pyrophosphate phosphatase(gene name synonym)|uniprotkb:YGR036C(locus name) psi-mi:alg14_yeast(display_long)|uniprotkb:YBR070C(locus name)|uniprotkb:YBR0711(orf name)|uniprotkb:Asparagine-linked glycosylation protein 14(gene name synonym)|uniprotkb:ALG14(gene name)|psi-mi:ALG14(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336679|imex:IM-14275-2068 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003268|refseq:NP_011550.3|dip:DIP-5237N|mint:P53223|ensemblfungi:YGR036C(gene)|ensemblfungi:YGR036C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0047874"(dolichyldiphosphatase activity)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR039666|interpro:IPR039667|reactome:R-SCE-446199 refseq:NP_009626.1|sgd:S000000274|mint:P38242|dip:DIP-5670N|ensemblfungi:YBR070C(gene)|ensemblfungi:YBR070C_mRNA(transcript)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043541"(UDP-N-acetylglucosamine transferase complex)|interpro:IPR013969(Oligosaccharide biosynthesis protein Alg14 like) psi-mi:"MI:0469"(intact) crc64:C8EC49CBFC08F8F8 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:qhGZMd77fH1ChaW9F7B1Uxvf2M0559292 rogid:2AdqgTHt69tIUjJTmhqzAPZGNe4559292 intact-crc:A2C2B84795AEA71D|rigid:gVLBVMwj3PU8ilqVnrxR89F59ic false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53223 uniprotkb:P53223 intact:EBI-23136|uniprotkb:D6VUH3|uniprotkb:Q45U47|ensemblfungi:YGR036C intact:EBI-23136|uniprotkb:D6VUH3|uniprotkb:Q45U47|ensemblfungi:YGR036C psi-mi:cax4_yeast(display_long)|uniprotkb:CAX4(gene name)|psi-mi:CAX4(display_short)|uniprotkb:CWH8(gene name synonym)|uniprotkb:Dolichyl pyrophosphate phosphatase(gene name synonym)|uniprotkb:YGR036C(locus name) psi-mi:cax4_yeast(display_long)|uniprotkb:CAX4(gene name)|psi-mi:CAX4(display_short)|uniprotkb:CWH8(gene name synonym)|uniprotkb:Dolichyl pyrophosphate phosphatase(gene name synonym)|uniprotkb:YGR036C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336690|imex:IM-14275-2069 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003268|refseq:NP_011550.3|dip:DIP-5237N|mint:P53223|ensemblfungi:YGR036C(gene)|ensemblfungi:YGR036C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0047874"(dolichyldiphosphatase activity)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR039666|interpro:IPR039667|reactome:R-SCE-446199 sgd:S000003268|refseq:NP_011550.3|dip:DIP-5237N|mint:P53223|ensemblfungi:YGR036C(gene)|ensemblfungi:YGR036C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0047874"(dolichyldiphosphatase activity)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR039666|interpro:IPR039667|reactome:R-SCE-446199 psi-mi:"MI:0469"(intact) crc64:C8EC49CBFC08F8F8 crc64:C8EC49CBFC08F8F8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:qhGZMd77fH1ChaW9F7B1Uxvf2M0559292 rogid:qhGZMd77fH1ChaW9F7B1Uxvf2M0559292 intact-crc:493D0EB36B3536B7|rigid:O9bAkTIza0DREqZ35yzftIQFOoo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53235 uniprotkb:P06634 intact:EBI-23172|uniprotkb:D6VUI9|uniprotkb:Q45U32|ensemblfungi:YGR054W intact:EBI-5744|uniprotkb:D6W2R0|ensemblfungi:YOR204W psi-mi:eif2a_yeast(display_long)|uniprotkb:YGR054W(locus name) psi-mi:ded1_yeast(display_long)|uniprotkb:DED1(gene name)|psi-mi:DED1(display_short)|uniprotkb:SPP81(gene name synonym)|uniprotkb:YOR204W(locus name)|uniprotkb:DEAD box protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336701|imex:IM-14275-2070 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003286|refseq:NP_011568.3|dip:DIP-5518N|mint:P53235|ensemblfungi:YGR054W(gene)|ensemblfungi:YGR054W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like) sgd:S000005730|refseq:NP_014847.3|dip:DIP-5820N|mint:P06634|ensemblfungi:YOR204W(gene)|ensemblfungi:YOR204W_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) crc64:F3C2E78504D83418 crc64:B6722D94C03BFA4B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:x8zDCH5W5GusC7qYd0mDATXhGVI559292 rogid:FkldumX6m5gBuuaG09aTJ0kuMZM559292 intact-crc:00A6A4FC5C876073|rigid:lEJcSZk9BR6cpQARI5atWZQeBsk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53235 uniprotkb:P24276 intact:EBI-23172|uniprotkb:D6VUI9|uniprotkb:Q45U32|ensemblfungi:YGR054W intact:EBI-18153|uniprotkb:D6VSS2|ensemblfungi:YDR293C psi-mi:eif2a_yeast(display_long)|uniprotkb:YGR054W(locus name) psi-mi:ssd1_yeast(display_long)|uniprotkb:SSD1(gene name)|psi-mi:SSD1(display_short)|uniprotkb:CLA1(gene name synonym)|uniprotkb:RLD1(gene name synonym)|uniprotkb:SRK1(gene name synonym)|uniprotkb:YDR293C(locus name)|uniprotkb:D9819.4(orf name)|uniprotkb:Protein SRK1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336712|imex:IM-14275-2071 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003286|refseq:NP_011568.3|dip:DIP-5518N|mint:P53235|ensemblfungi:YGR054W(gene)|ensemblfungi:YGR054W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like) refseq:NP_010579.1|sgd:S000002701|ensemblfungi:YDR293C(gene)|ensemblfungi:YDR293C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051301"(cell division)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR041093|interpro:IPR041505|rcsb pdb:5NCL|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007049"(cell cycle)|dip:DIP-6449N|mint:P24276 psi-mi:"MI:0469"(intact) crc64:F3C2E78504D83418 crc64:3D50FD6838ECA514 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:x8zDCH5W5GusC7qYd0mDATXhGVI559292 rogid:myt8+lnu2/li6TuGiM5GBfMtUiw559292 intact-crc:801903E9F6934A03|rigid:ix7pLPTpBBUG8rMgk3pbmwk5RUI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53235 uniprotkb:P25567 intact:EBI-23172|uniprotkb:D6VUI9|uniprotkb:Q45U32|ensemblfungi:YGR054W intact:EBI-18084|uniprotkb:D6VQX8|ensemblfungi:YCL037C psi-mi:eif2a_yeast(display_long)|uniprotkb:YGR054W(locus name) psi-mi:sro9_yeast(display_long)|uniprotkb:SRO9(gene name)|psi-mi:SRO9(display_short)|uniprotkb:YCL037C(locus name)|uniprotkb:YCL37C(orf name)|uniprotkb:Suppressor of RHO3 protein 9(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336723|imex:IM-14275-2072 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003286|refseq:NP_011568.3|dip:DIP-5518N|mint:P53235|ensemblfungi:YGR054W(gene)|ensemblfungi:YGR054W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like) refseq:NP_009893.2|sgd:S000000542|ensemblfungi:YCL037C(gene)|ensemblfungi:YCL037C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|dip:DIP-6638N|mint:P25567 psi-mi:"MI:0469"(intact) crc64:F3C2E78504D83418 crc64:B1B720D40C7B9914 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:x8zDCH5W5GusC7qYd0mDATXhGVI559292 rogid:CouwiBsK7S3Tm6CoBsu3LdWfelg559292 intact-crc:1B0ACB8C4F489D08|rigid:zsC0qXJc7qCFCxEE0hCWf0Cssew false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53235 uniprotkb:P38263 intact:EBI-23172|uniprotkb:D6VUI9|uniprotkb:Q45U32|ensemblfungi:YGR054W intact:EBI-20304|uniprotkb:D6VQA4|ensemblfungi:YBR105C psi-mi:eif2a_yeast(display_long)|uniprotkb:YGR054W(locus name) psi-mi:gid4_yeast(display_long)|uniprotkb:VID24(gene name)|psi-mi:VID24(display_short)|uniprotkb:YBR105C(locus name)|uniprotkb:YBR0834(orf name)|uniprotkb:GID4(gene name synonym)|uniprotkb:Glucose-induced degradation protein 4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336734|imex:IM-14275-2073 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003286|refseq:NP_011568.3|dip:DIP-5518N|mint:P53235|ensemblfungi:YGR054W(gene)|ensemblfungi:YGR054W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like) refseq:NP_009663.1|sgd:S000000309|ensemblfungi:YBR105C(gene)|ensemblfungi:YBR105C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0007039"(protein catabolic process in the vacuole)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR018618|rcsb pdb:6SWY|dip:DIP-4502N|mint:P38263 psi-mi:"MI:0469"(intact) crc64:F3C2E78504D83418 crc64:FF020B239676E0B2 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:x8zDCH5W5GusC7qYd0mDATXhGVI559292 rogid:ag6caXMIP/qIv27yJtSEmlBoI7g559292 intact-crc:2DC93B9CDBB1FDCB|rigid:ZANT+YY2BhjEBDmPBYmXP4kkhp8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53235 uniprotkb:P53235 intact:EBI-23172|uniprotkb:D6VUI9|uniprotkb:Q45U32|ensemblfungi:YGR054W intact:EBI-23172|uniprotkb:D6VUI9|uniprotkb:Q45U32|ensemblfungi:YGR054W psi-mi:eif2a_yeast(display_long)|uniprotkb:YGR054W(locus name) psi-mi:eif2a_yeast(display_long)|uniprotkb:YGR054W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336745|imex:IM-14275-2074 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003286|refseq:NP_011568.3|dip:DIP-5518N|mint:P53235|ensemblfungi:YGR054W(gene)|ensemblfungi:YGR054W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like) sgd:S000003286|refseq:NP_011568.3|dip:DIP-5518N|mint:P53235|ensemblfungi:YGR054W(gene)|ensemblfungi:YGR054W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like) psi-mi:"MI:0469"(intact) crc64:F3C2E78504D83418 crc64:F3C2E78504D83418 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:x8zDCH5W5GusC7qYd0mDATXhGVI559292 rogid:x8zDCH5W5GusC7qYd0mDATXhGVI559292 intact-crc:70958D771A812F07|rigid:RwT8pEFBNX7TDjSPular29DC5TE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53235 uniprotkb:P53849 intact:EBI-23172|uniprotkb:D6VUI9|uniprotkb:Q45U32|ensemblfungi:YGR054W intact:EBI-29244|uniprotkb:D6W0T8|ensemblfungi:YNL255C psi-mi:eif2a_yeast(display_long)|uniprotkb:YGR054W(locus name) psi-mi:gis2_yeast(display_long)|uniprotkb:GIS2(gene name)|psi-mi:GIS2(display_short)|uniprotkb:N0852(orf name)|uniprotkb:YNL255C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336756|imex:IM-14275-2075 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003286|refseq:NP_011568.3|dip:DIP-5518N|mint:P53235|ensemblfungi:YGR054W(gene)|ensemblfungi:YGR054W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like) refseq:NP_014144.1|sgd:S000005199|dip:DIP-2669N|mint:P53849|ensemblfungi:YNL255C(gene)|ensemblfungi:YNL255C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045182"(translation regulator activity)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875 psi-mi:"MI:0469"(intact) crc64:F3C2E78504D83418 crc64:E72696428F85CA3F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:x8zDCH5W5GusC7qYd0mDATXhGVI559292 rogid:kftHFJVi7QRZASmr4hLdALvleR4559292 intact-crc:B10F95551F760D22|rigid:HPiuGydc1K19TStzhsSnRQ4xjdw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53241 uniprotkb:P19807 intact:EBI-20297|uniprotkb:D6VUJ9|ensemblfungi:YGR065C intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:vht1_yeast(display_long)|uniprotkb:VHT1(gene name)|psi-mi:VHT1(display_short)|uniprotkb:YGR065C(locus name)|uniprotkb:"H(+)/biotin symporter"(gene name synonym) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336767|imex:IM-14275-2076 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011579.1|sgd:S000003297|ensemblfungi:YGR065C(gene)|ensemblfungi:YGR065C_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015225"(biotin transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015878"(biotin transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259|go:"GO:0031224"(intrinsic component of membrane)|dip:DIP-5519N|mint:P53241 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:QcsXV+nHmN0tuKMiB1DGKpAFth4559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:2AD5E09892DCA8D1|rigid:BNObvqc10m5Ngt8pnI3ipUI/+JQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53241 uniprotkb:P35735 intact:EBI-20297|uniprotkb:D6VUJ9|ensemblfungi:YGR065C intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:vht1_yeast(display_long)|uniprotkb:VHT1(gene name)|psi-mi:VHT1(display_short)|uniprotkb:YGR065C(locus name)|uniprotkb:"H(+)/biotin symporter"(gene name synonym) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336778|imex:IM-14275-2077 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011579.1|sgd:S000003297|ensemblfungi:YGR065C(gene)|ensemblfungi:YGR065C_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015225"(biotin transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015878"(biotin transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259|go:"GO:0031224"(intrinsic component of membrane)|dip:DIP-5519N|mint:P53241 refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:QcsXV+nHmN0tuKMiB1DGKpAFth4559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:E1F6F4C327D2FC4A|rigid:23J4EF3N/v1/gYU2joMntbEN6V0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53241 uniprotkb:P36027 intact:EBI-20297|uniprotkb:D6VUJ9|ensemblfungi:YGR065C intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:vht1_yeast(display_long)|uniprotkb:VHT1(gene name)|psi-mi:VHT1(display_short)|uniprotkb:YGR065C(locus name)|uniprotkb:"H(+)/biotin symporter"(gene name synonym) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336789|imex:IM-14275-2078 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011579.1|sgd:S000003297|ensemblfungi:YGR065C(gene)|ensemblfungi:YGR065C_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015225"(biotin transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015878"(biotin transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259|go:"GO:0031224"(intrinsic component of membrane)|dip:DIP-5519N|mint:P53241 ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:QcsXV+nHmN0tuKMiB1DGKpAFth4559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:E218E26959838AFD|rigid:sfswFSEWAyW90g9TmiRoSNrPGPQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38234 uniprotkb:P53241 intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C intact:EBI-20297|uniprotkb:D6VUJ9|ensemblfungi:YGR065C psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:vht1_yeast(display_long)|uniprotkb:VHT1(gene name)|psi-mi:VHT1(display_short)|uniprotkb:YGR065C(locus name)|uniprotkb:"H(+)/biotin symporter"(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336800|imex:IM-14275-2079 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 refseq:NP_011579.1|sgd:S000003297|ensemblfungi:YGR065C(gene)|ensemblfungi:YGR065C_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015225"(biotin transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015878"(biotin transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259|go:"GO:0031224"(intrinsic component of membrane)|dip:DIP-5519N|mint:P53241 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 rogid:QcsXV+nHmN0tuKMiB1DGKpAFth4559292 intact-crc:0056382A9ABD1F34|rigid:PoXiALx3WiHgZJQbJj2YLKfMkIk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53241 uniprotkb:P50276 intact:EBI-20297|uniprotkb:D6VUJ9|ensemblfungi:YGR065C intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:vht1_yeast(display_long)|uniprotkb:VHT1(gene name)|psi-mi:VHT1(display_short)|uniprotkb:YGR065C(locus name)|uniprotkb:"H(+)/biotin symporter"(gene name synonym) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336811|imex:IM-14275-2080 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011579.1|sgd:S000003297|ensemblfungi:YGR065C(gene)|ensemblfungi:YGR065C_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015225"(biotin transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015878"(biotin transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259|go:"GO:0031224"(intrinsic component of membrane)|dip:DIP-5519N|mint:P53241 ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:QcsXV+nHmN0tuKMiB1DGKpAFth4559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:61A94548B4BBEC21|rigid:xxKA/yBOlInTV7tqTErRDCCejqw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53278 uniprotkb:P53241 intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C intact:EBI-20297|uniprotkb:D6VUJ9|ensemblfungi:YGR065C psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name) psi-mi:vht1_yeast(display_long)|uniprotkb:VHT1(gene name)|psi-mi:VHT1(display_short)|uniprotkb:YGR065C(locus name)|uniprotkb:"H(+)/biotin symporter"(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336822|imex:IM-14275-2081 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome) refseq:NP_011579.1|sgd:S000003297|ensemblfungi:YGR065C(gene)|ensemblfungi:YGR065C_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015225"(biotin transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015878"(biotin transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259|go:"GO:0031224"(intrinsic component of membrane)|dip:DIP-5519N|mint:P53241 psi-mi:"MI:0469"(intact) crc64:D482327C9274C026 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292 rogid:QcsXV+nHmN0tuKMiB1DGKpAFth4559292 intact-crc:615917C6F545261F|rigid:SoAb7CL5LFAcskUYCP/myqB/+iw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53241 uniprotkb:Q02785 intact:EBI-20297|uniprotkb:D6VUJ9|ensemblfungi:YGR065C intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:vht1_yeast(display_long)|uniprotkb:VHT1(gene name)|psi-mi:VHT1(display_short)|uniprotkb:YGR065C(locus name)|uniprotkb:"H(+)/biotin symporter"(gene name synonym) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336833|imex:IM-14275-2082 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011579.1|sgd:S000003297|ensemblfungi:YGR065C(gene)|ensemblfungi:YGR065C_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015225"(biotin transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015878"(biotin transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259|go:"GO:0031224"(intrinsic component of membrane)|dip:DIP-5519N|mint:P53241 refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:QcsXV+nHmN0tuKMiB1DGKpAFth4559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:D9C4538845A39663|rigid:SlSyDZJxyAnEJLhb1LMkuWqbeGI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53241 uniprotkb:Q03640 intact:EBI-20297|uniprotkb:D6VUJ9|ensemblfungi:YGR065C intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:vht1_yeast(display_long)|uniprotkb:VHT1(gene name)|psi-mi:VHT1(display_short)|uniprotkb:YGR065C(locus name)|uniprotkb:"H(+)/biotin symporter"(gene name synonym) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336844|imex:IM-14275-2083 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011579.1|sgd:S000003297|ensemblfungi:YGR065C(gene)|ensemblfungi:YGR065C_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015225"(biotin transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015878"(biotin transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259|go:"GO:0031224"(intrinsic component of membrane)|dip:DIP-5519N|mint:P53241 refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) - crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:QcsXV+nHmN0tuKMiB1DGKpAFth4559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:97F456A5EC13C13E|rigid:l55bSa78Mud9WLtRQ8gLHlBFt5Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06689 uniprotkb:P53241 intact:EBI-38659|uniprotkb:D6VZ50|ensemblfungi:YLR413W intact:EBI-20297|uniprotkb:D6VUJ9|ensemblfungi:YGR065C psi-mi:yl413_yeast(display_long)|uniprotkb:YLR413W(locus name) psi-mi:vht1_yeast(display_long)|uniprotkb:VHT1(gene name)|psi-mi:VHT1(display_short)|uniprotkb:YGR065C(locus name)|uniprotkb:"H(+)/biotin symporter"(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336855|imex:IM-14275-2084 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013517.1|sgd:S000004405|mint:Q06689|dip:DIP-5075N|ensemblfungi:YLR413W(gene)|ensemblfungi:YLR413W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0071944"(cell periphery)|interpro:IPR009571(SUR7) refseq:NP_011579.1|sgd:S000003297|ensemblfungi:YGR065C(gene)|ensemblfungi:YGR065C_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015225"(biotin transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015878"(biotin transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259|go:"GO:0031224"(intrinsic component of membrane)|dip:DIP-5519N|mint:P53241 psi-mi:"MI:0469"(intact) crc64:92E23436DC857E95 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AoTGKjLhw0NECrtuftZqLANonds559292 rogid:QcsXV+nHmN0tuKMiB1DGKpAFth4559292 intact-crc:4B443CE612DAA0F4|rigid:pxMK91SaoqFcSUckeqldpUhMIwg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53241 uniprotkb:Q07651 intact:EBI-20297|uniprotkb:D6VUJ9|ensemblfungi:YGR065C intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:vht1_yeast(display_long)|uniprotkb:VHT1(gene name)|psi-mi:VHT1(display_short)|uniprotkb:YGR065C(locus name)|uniprotkb:"H(+)/biotin symporter"(gene name synonym) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336866|imex:IM-14275-2085 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011579.1|sgd:S000003297|ensemblfungi:YGR065C(gene)|ensemblfungi:YGR065C_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015225"(biotin transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015878"(biotin transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259|go:"GO:0031224"(intrinsic component of membrane)|dip:DIP-5519N|mint:P53241 refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:QcsXV+nHmN0tuKMiB1DGKpAFth4559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:D7EFA1F60BEEF3A3|rigid:6OuyD+ARV3IT8CkzXj9hzFmjVP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17555 uniprotkb:P53250 intact:EBI-4024|uniprotkb:D6W144|ensemblfungi:YNL138W intact:EBI-19663|uniprotkb:D6VUL2|ensemblfungi:YGR080W psi-mi:cap_yeast(display_long)|uniprotkb:SRV2(gene name)|psi-mi:SRV2(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:YNL138W(locus name)|uniprotkb:N1210(orf name)|uniprotkb:N1838(orf name) psi-mi:twf1_yeast(display_long)|uniprotkb:TWF1(gene name)|psi-mi:TWF1(display_short)|uniprotkb:YGR080W(locus name)|uniprotkb:Twinfilin-A(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336877|imex:IM-14275-2086 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014261.1|sgd:S000005082|dip:DIP-77N|ensemblfungi:YNL138W(gene)|ensemblfungi:YNL138W_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007265"(Ras protein signal transduction)|mint:P17555|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0051014"(actin filament severing)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|rcsb pdb:1K4Z|rcsb pdb:1KQ5|reactome:R-SCE-6798695 sgd:S000003312|ensemblfungi:YGR080W(gene)|ensemblfungi:YGR080W_mRNA(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0007015"(actin filament organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|refseq:NP_011594.3|dip:DIP-2202N|mint:P53250 psi-mi:"MI:0469"(intact) crc64:0EB4D41205E2D464 crc64:D9213BBB2D953DBD figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3Fs9g+L5RnbkqYThVpOvSFrZoJ8559292 rogid:dRJKUwolfd9OK7V77leZs+qODHc559292 intact-crc:250EA7F2FD853091|rigid:h6hkoHUW8tRGVVE+RDmgfFtoq1M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53250 uniprotkb:P53250 intact:EBI-19663|uniprotkb:D6VUL2|ensemblfungi:YGR080W intact:EBI-19663|uniprotkb:D6VUL2|ensemblfungi:YGR080W psi-mi:twf1_yeast(display_long)|uniprotkb:TWF1(gene name)|psi-mi:TWF1(display_short)|uniprotkb:YGR080W(locus name)|uniprotkb:Twinfilin-A(gene name synonym) psi-mi:twf1_yeast(display_long)|uniprotkb:TWF1(gene name)|psi-mi:TWF1(display_short)|uniprotkb:YGR080W(locus name)|uniprotkb:Twinfilin-A(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336888|imex:IM-14275-2087 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003312|ensemblfungi:YGR080W(gene)|ensemblfungi:YGR080W_mRNA(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0007015"(actin filament organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|refseq:NP_011594.3|dip:DIP-2202N|mint:P53250 sgd:S000003312|ensemblfungi:YGR080W(gene)|ensemblfungi:YGR080W_mRNA(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0007015"(actin filament organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|refseq:NP_011594.3|dip:DIP-2202N|mint:P53250 psi-mi:"MI:0469"(intact) crc64:D9213BBB2D953DBD crc64:D9213BBB2D953DBD figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dRJKUwolfd9OK7V77leZs+qODHc559292 rogid:dRJKUwolfd9OK7V77leZs+qODHc559292 intact-crc:004F3CE52F68DDDE|rigid:HhSPlBrLZcEpN1JkBnNRkv6KCik false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25847 uniprotkb:P53257 intact:EBI-11352|uniprotkb:Q12423|ensemblfungi:YOL090W|uniprotkb:D6W1X8 intact:EBI-2095999|uniprotkb:D6VUM8|uniprotkb:Q6B1H1|ensemblfungi:YGR096W psi-mi:msh2_yeast(display_long)|uniprotkb:MSH2(gene name)|psi-mi:MSH2(display_short)|uniprotkb:YOL090W(locus name)|uniprotkb:O0935(orf name)|uniprotkb:MutS protein homolog 2(gene name synonym) psi-mi:tpc1_yeast(display_long)|uniprotkb:TPC1(gene name)|psi-mi:TPC1(display_short)|uniprotkb:YGR096W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336899|imex:IM-14275-2088 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOL090W(gene)|ensemblfungi:YOL090W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000735"(removal of nonhomologous ends)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0006312"(mitotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043111"(replication fork arrest)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR032642|interpro:IPR036187|interpro:IPR036678|reactome:R-SCE-5358565|reactome:R-SCE-5358606|go:"GO:0032300"(mismatch repair complex)|refseq:NP_014551.1|sgd:S000005450|mint:P25847|dip:DIP-2415N sgd:S000003328|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|refseq:NP_011610.3|mint:P53257|ensemblfungi:YGR096W(gene)|ensemblfungi:YGR096W_mRNA(transcript)|go:"GO:0015234"(thiamine transmembrane transporter activity)|go:"GO:0030974"(thiamine pyrophosphate transmembrane transport)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0090422"(thiamine pyrophosphate transmembrane transporter activity)|go:"GO:1990545"(mitochondrial thiamine pyrophosphate transmembrane transport)|reactome:R-SCE-196819 psi-mi:"MI:0469"(intact) crc64:43FFD8A640138AE4 - figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:PNwekSiaI58qR+dPZZQW5UNRJ+4559292 rogid:KLSwJwvhee0S78g9AUVAnkpqZQk559292 intact-crc:FF55D2EAD8854807|rigid:QjhJkEcTttdZ7FxMJTw6O5xflFk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53261 uniprotkb:P21304 intact:EBI-13145|ensemblfungi:YGR103W|uniprotkb:D6VUN5 intact:EBI-14328|uniprotkb:D6VYJ9|ensemblfungi:YLR196W psi-mi:pesc_yeast(display_long)|uniprotkb:NOP7(gene name)|psi-mi:NOP7(display_short)|uniprotkb:YPH1(gene name synonym)|uniprotkb:Nucleolar protein 7(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 13(gene name synonym)|uniprotkb:RRP13(gene name synonym)|uniprotkb:YGR103W(locus name) psi-mi:pwp1_yeast(display_long)|uniprotkb:L8167.10(orf name)|uniprotkb:YLR196W(locus name)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336910|imex:IM-14275-2089 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011617.1|sgd:S000003335|ensemblfungi:YGR103W(gene)|ensemblfungi:YGR103W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0070545"(PeBoW complex)|interpro:IPR001357(BRCT)|interpro:IPR010613(Pescadillo, N-terminal)|interpro:IPR036420|rcsb pdb:3JCT|rcsb pdb:5Z3G|mint:P53261|dip:DIP-6326N|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:7BTB|reactome:R-SCE-6791226 refseq:NP_013297.1|sgd:S000004186|ensemblfungi:YLR196W(gene)|ensemblfungi:YLR196W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR044285|mint:P21304|dip:DIP-4203N psi-mi:"MI:0469"(intact) crc64:131001C956787BE5 crc64:FC0189B289494AB5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:c+2tmQ08S4VYW9o25XrTj0DEm4c559292 rogid:Q1nPXtlkpIw8JosaiYX0PSVNaSw559292 intact-crc:901141BABA35E10B|rigid:A2uOdgJzJiqsf7w6AShm3PRYUsM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38779 uniprotkb:P53261 intact:EBI-24538|uniprotkb:D3DL01|ensemblfungi:YHR052W intact:EBI-13145|ensemblfungi:YGR103W|uniprotkb:D6VUN5 psi-mi:cic1_yeast(display_long)|uniprotkb:CIC1(gene name)|psi-mi:CIC1(display_short)|uniprotkb:NSA3(gene name synonym)|uniprotkb:Core interacting component 1(gene name synonym)|uniprotkb:YHR052W(locus name) psi-mi:pesc_yeast(display_long)|uniprotkb:NOP7(gene name)|psi-mi:NOP7(display_short)|uniprotkb:YPH1(gene name synonym)|uniprotkb:Nucleolar protein 7(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 13(gene name synonym)|uniprotkb:RRP13(gene name synonym)|uniprotkb:YGR103W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336921|imex:IM-14275-2090 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011919.1|sgd:S000001094|dip:DIP-6491N|mint:P38779|ensemblfungi:YHR052W(gene)|ensemblfungi:YHR052W_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0019843"(rRNA binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0070628"(proteasome binding)|interpro:IPR023674|interpro:IPR028364|interpro:IPR028365|rcsb pdb:3JCT|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6M62|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BTB|go:"GO:0034513"(box H/ACA snoRNA binding) refseq:NP_011617.1|sgd:S000003335|ensemblfungi:YGR103W(gene)|ensemblfungi:YGR103W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0070545"(PeBoW complex)|interpro:IPR001357(BRCT)|interpro:IPR010613(Pescadillo, N-terminal)|interpro:IPR036420|rcsb pdb:3JCT|rcsb pdb:5Z3G|mint:P53261|dip:DIP-6326N|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:7BTB|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:13A2AFA0B927CD98 crc64:131001C956787BE5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rdhoaLdCr+bDCy9BYwEA9foQFWQ559292 rogid:c+2tmQ08S4VYW9o25XrTj0DEm4c559292 intact-crc:773FAF0F6746622C|rigid:upcZZg18E+MX4sfyCbcyEwhHTmc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39744 uniprotkb:P53261 intact:EBI-29259|uniprotkb:Q08625|uniprotkb:D6W2R2|ensemblfungi:YOR206W intact:EBI-13145|ensemblfungi:YGR103W|uniprotkb:D6VUN5 psi-mi:noc2_yeast(display_long)|uniprotkb:YOX001(orf name)|uniprotkb:YOR206W(locus name)|uniprotkb:NOC2(gene name)|psi-mi:NOC2(display_short) psi-mi:pesc_yeast(display_long)|uniprotkb:NOP7(gene name)|psi-mi:NOP7(display_short)|uniprotkb:YPH1(gene name synonym)|uniprotkb:Nucleolar protein 7(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 13(gene name synonym)|uniprotkb:RRP13(gene name synonym)|uniprotkb:YGR103W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336932|imex:IM-14275-2091 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014849.3|sgd:S000005732|dip:DIP-4559N|mint:P39744|ensemblfungi:YOR206W(gene)|ensemblfungi:YOR206W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR005343(Protein of unknown function UPF0120) refseq:NP_011617.1|sgd:S000003335|ensemblfungi:YGR103W(gene)|ensemblfungi:YGR103W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0070545"(PeBoW complex)|interpro:IPR001357(BRCT)|interpro:IPR010613(Pescadillo, N-terminal)|interpro:IPR036420|rcsb pdb:3JCT|rcsb pdb:5Z3G|mint:P53261|dip:DIP-6326N|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:7BTB|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:48C3B9AE076B9B8F crc64:131001C956787BE5 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:d5I8KJOSG63bZ/Pt+XvKdy/SWws559292 rogid:c+2tmQ08S4VYW9o25XrTj0DEm4c559292 intact-crc:866FC33DC9D2D763|rigid:Nbhs9sNtAht584dYslqrQIAjzvA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53267 uniprotkb:P53289 intact:EBI-23268|uniprotkb:Q9P422|uniprotkb:D6VUP6|ensemblfungi:YGR113W intact:EBI-23393|uniprotkb:D6VUU0|uniprotkb:Q7ZA12|ensemblfungi:YGR161C psi-mi:dam1_yeast(display_long)|uniprotkb:YGR113W(locus name)|uniprotkb:G6153(orf name)|uniprotkb:DAM1(gene name)|psi-mi:DAM1(display_short)|uniprotkb:Outer kinetochore protein DAM1(gene name synonym)|uniprotkb:DUO1 and MPS1-interacting protein 1(gene name synonym)|uniprotkb:Kinetochore assembly protein DAM1(gene name synonym) psi-mi:rts3_yeast(display_long)|uniprotkb:RTS3(gene name)|psi-mi:RTS3(display_short)|uniprotkb:YGR161C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336943|imex:IM-14275-2092 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003345|refseq:NP_011628.4|dip:DIP-1286N|mint:P53267|ensemblfungi:YGR113W(gene)|ensemblfungi:YGR113W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0042729"(DASH complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:1990537"(mitotic spindle polar microtubule)|go:"GO:1990758"(mitotic sister chromatid biorientation)|interpro:IPR013962(DASH complex, subunit Dam1) sgd:S000003393|refseq:NP_011677.3|dip:DIP-6319N|mint:P53289|ensemblfungi:YGR161C(gene)|ensemblfungi:YGR161C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm) psi-mi:"MI:0469"(intact) crc64:F02DB6EE09BC2284 crc64:BA31D32B9ADF02AB figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1U/NNQaGUzoddr+E0JlnygELpCc559292 rogid:0xYKXiuXiyBDogpuE8vOl7hUekQ559292 intact-crc:2A432CE39D28B59E|rigid:H3kdW/21HV1NUYICgdLOH4WwJfU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53276 uniprotkb:P38882 intact:EBI-23301|uniprotkb:D6VUR0|ensemblfungi:YGR128C intact:EBI-24892|uniprotkb:D3DLE4|ensemblfungi:YHR196W psi-mi:utp8_yeast(display_long)|uniprotkb:UTP8(gene name)|psi-mi:UTP8(display_short)|uniprotkb:t-UTP8(gene name synonym)|uniprotkb:U three protein 8(gene name synonym)|uniprotkb:U3 protein 8 required for transcription(gene name synonym)|uniprotkb:YGR128C(locus name) psi-mi:utp9_yeast(display_long)|uniprotkb:t-UTP9(gene name synonym)|uniprotkb:UTP9(gene name)|psi-mi:UTP9(display_short)|uniprotkb:U three protein 9(gene name synonym)|uniprotkb:U3 protein 9 required for transcription(gene name synonym)|uniprotkb:YHR196W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336954|imex:IM-14275-2093 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003360|refseq:NP_011644.3|dip:DIP-6747N|mint:P53276|ensemblfungi:YGR128C(gene)|ensemblfungi:YGR128C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005730"(nucleolus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034455"(t-UTP complex)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR018843|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU refseq:NP_012066.1|sgd:S000001239|mint:P38882|dip:DIP-6634N|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|ensemblfungi:YHR196W(gene)|ensemblfungi:YHR196W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034455"(t-UTP complex)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4 psi-mi:"MI:0469"(intact) crc64:6F5AE1492F841F49 crc64:0C482C6A32855FF1 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dG2UtBMuPQujwdovAL/FDjpqps0559292 rogid:cjrwDuKyMEgU0Zgn28yzNi6haV4559292 intact-crc:1B9708DEAE0B1EA1|rigid:27wHldw0PK5/5pv+jI6DT23tC24 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04177 uniprotkb:P53276 intact:EBI-35844|uniprotkb:D6VT31|ensemblfungi:YDR398W intact:EBI-23301|uniprotkb:D6VUR0|ensemblfungi:YGR128C psi-mi:utp5_yeast(display_long)|uniprotkb:U three protein 5(gene name synonym)|uniprotkb:U3 protein 5 required for transcription(gene name synonym)|uniprotkb:D9509.17(orf name)|uniprotkb:YDR398W(locus name)|uniprotkb:UTP5(gene name)|psi-mi:UTP5(display_short)|uniprotkb:t-UTP5(gene name synonym) psi-mi:utp8_yeast(display_long)|uniprotkb:UTP8(gene name)|psi-mi:UTP8(display_short)|uniprotkb:t-UTP8(gene name synonym)|uniprotkb:U three protein 8(gene name synonym)|uniprotkb:U3 protein 8 required for transcription(gene name synonym)|uniprotkb:YGR128C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336965|imex:IM-14275-2094 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010686.1|sgd:S000002806|mint:Q04177|dip:DIP-1317N|ensemblfungi:YDR398W(gene)|ensemblfungi:YDR398W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034455"(t-UTP complex)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|rcsb pdb:6LQS sgd:S000003360|refseq:NP_011644.3|dip:DIP-6747N|mint:P53276|ensemblfungi:YGR128C(gene)|ensemblfungi:YGR128C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005730"(nucleolus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034455"(t-UTP complex)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR018843|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU psi-mi:"MI:0469"(intact) crc64:7A6F60C7C6F46C2A crc64:6F5AE1492F841F49 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cpoFrHdK29TtGOfAINI5ceEgO3U559292 rogid:dG2UtBMuPQujwdovAL/FDjpqps0559292 intact-crc:7E1284E45ED80E20|rigid:0j/3hCuxKGW4YCeNfxcgt+nBaVk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53276 uniprotkb:Q04305 intact:EBI-23301|uniprotkb:D6VUR0|ensemblfungi:YGR128C intact:EBI-28183|uniprotkb:D6VZR6|ensemblfungi:YMR093W psi-mi:utp8_yeast(display_long)|uniprotkb:UTP8(gene name)|psi-mi:UTP8(display_short)|uniprotkb:t-UTP8(gene name synonym)|uniprotkb:U three protein 8(gene name synonym)|uniprotkb:U3 protein 8 required for transcription(gene name synonym)|uniprotkb:YGR128C(locus name) psi-mi:utp15_yeast(display_long)|uniprotkb:U three protein 15(gene name synonym)|uniprotkb:U3 protein 15 required for transcription(gene name synonym)|uniprotkb:YM9582.18(orf name)|uniprotkb:YMR093W(locus name)|uniprotkb:UTP15(gene name)|psi-mi:UTP15(display_short)|uniprotkb:t-UTP15(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336976|imex:IM-14275-2095 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003360|refseq:NP_011644.3|dip:DIP-6747N|mint:P53276|ensemblfungi:YGR128C(gene)|ensemblfungi:YGR128C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005730"(nucleolus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034455"(t-UTP complex)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR018843|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU refseq:NP_013811.1|sgd:S000004699|dip:DIP-1962N|mint:Q04305|ensemblfungi:YMR093W(gene)|ensemblfungi:YMR093W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034455"(t-UTP complex)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018983|interpro:IPR019775|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:6F5AE1492F841F49 crc64:2B74BA8BD496C8DA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dG2UtBMuPQujwdovAL/FDjpqps0559292 rogid:4DswftRHSsPlKxMEIH1VnCc98r8559292 intact-crc:E95C02EBF18534FA|rigid:476Y4hMPsXrZCUY0/CehTXJ8mv8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53276 uniprotkb:Q06679 intact:EBI-23301|uniprotkb:D6VUR0|ensemblfungi:YGR128C intact:EBI-35712|uniprotkb:D6VSV7|ensemblfungi:YDR324C psi-mi:utp8_yeast(display_long)|uniprotkb:UTP8(gene name)|psi-mi:UTP8(display_short)|uniprotkb:t-UTP8(gene name synonym)|uniprotkb:U three protein 8(gene name synonym)|uniprotkb:U3 protein 8 required for transcription(gene name synonym)|uniprotkb:YGR128C(locus name) psi-mi:utp4_yeast(display_long)|uniprotkb:UTP4(gene name)|psi-mi:UTP4(display_short)|uniprotkb:t-UTP4(gene name synonym)|uniprotkb:U three protein 4(gene name synonym)|uniprotkb:U3 protein 4 required for transcription(gene name synonym)|uniprotkb:YDR324C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336987|imex:IM-14275-2096 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003360|refseq:NP_011644.3|dip:DIP-6747N|mint:P53276|ensemblfungi:YGR128C(gene)|ensemblfungi:YGR128C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005730"(nucleolus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034455"(t-UTP complex)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR018843|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU refseq:NP_010611.3|sgd:S000002732|mint:Q06679|dip:DIP-6436N|ensemblfungi:YDR324C(gene)|ensemblfungi:YDR324C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:6F5AE1492F841F49 crc64:5D1C77899CABB40B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dG2UtBMuPQujwdovAL/FDjpqps0559292 rogid:kAD4RO628jpcbjUoQXQbjcGVY88559292 intact-crc:F184DB91EEA78CFB|rigid:/wdgF347OTqJCoA5V1cQXG2zx9o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53283 uniprotkb:P19807 intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6336998|imex:IM-14275-2097 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:3A24DAA1708C67F3|rigid:Yep/60BJh8j6poTG9e9qGjIUufo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:P53283 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337009|imex:IM-14275-2098 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 intact-crc:212BE1DDD3C77429|rigid:u7jEPM32V8IpYlzT1htlf88byuA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32568 uniprotkb:P53283 intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337020|imex:IM-14275-2099 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 intact-crc:E2C480EE7090F20A|rigid:2bnGAL2x1xcs4Z36ix5ehVPjPxg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53283 uniprotkb:P33302 intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C intact:EBI-13038|uniprotkb:D6W2L0|ensemblfungi:YOR153W psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:pdr5_yeast(display_long)|uniprotkb:PDR5(gene name)|psi-mi:PDR5(display_short)|uniprotkb:LEM1(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 5(gene name synonym)|uniprotkb:Suppressor of toxicity of sporidesmin(gene name synonym)|uniprotkb:YOR153W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337031|imex:IM-14275-2100 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 sgd:S000005679|refseq:NP_014796.3|mint:P33302|dip:DIP-6776N|ensemblfungi:YOR153W(gene)|ensemblfungi:YOR153W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR029481|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 rogid:Sd6SJWf6B0rDZnLVaPHyvr4lhew559292 intact-crc:001F29A3FA3B9E67|rigid:zIdWycDKvwiiuk8OYBv7Mdsxnn0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:P53283 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337042|imex:IM-14275-2101 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 intact-crc:F107CEFAC5823368|rigid:wD8msNZeOvp2/Oq03bW4GKpXP74 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53283 uniprotkb:P36027 intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337053|imex:IM-14275-2102 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:F2E9D850BBD345DF|rigid:mtLwa5UD2no+KNX1zr+Rm6iBzdA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53283 uniprotkb:P38234 intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337064|imex:IM-14275-2103 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 intact-crc:10A7021378EDD016|rigid:6/V/xIMUx/bF6Xq+TON30eBUZa8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:P53283 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337075|imex:IM-14275-2104 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 intact-crc:724202136EA54FEF|rigid:y0li6KfPk5zOauC/WQjQrordZrs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53283 uniprotkb:P38695 intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337086|imex:IM-14275-2105 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N psi-mi:"MI:0469"(intact) - crc64:6906721BAC1A5F87 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 intact-crc:8FD08617E9178240|rigid:eeTtRNE+cPmOQAz+Fh4qKxGTVLs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53283 uniprotkb:P50276 intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337097|imex:IM-14275-2106 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:71587F7156EB2303|rigid:6tzNq2Ui8vhidQ2zGGPhgrv0Tf0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53283 uniprotkb:Q02785 intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337108|imex:IM-14275-2107 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:CD485381084E8C44|rigid:kBVFoVBcu+qgiyK1tafjYiSkXZ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53283 uniprotkb:Q03640 intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337119|imex:IM-14275-2108 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) - crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:837856ACA1FEDB19|rigid:632/xu49x0U8MagNYh6uo6o97+s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06451 uniprotkb:P53283 intact:EBI-34275|uniprotkb:D6W4F2|ensemblfungi:YPR156C intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:tpo3_yeast(display_long)|uniprotkb:TPO3(gene name)|psi-mi:TPO3(display_short)|uniprotkb:P9584.7(orf name)|uniprotkb:YPR156C(locus name) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337130|imex:IM-14275-2109 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015482.1|sgd:S000006360|mint:Q06451|dip:DIP-3907N|ensemblfungi:YPR156C(gene)|ensemblfungi:YPR156C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:D260ED161F800502 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oVpx7Bjk/mK2Q7+/j05tX3gHw7k559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 intact-crc:A27E4FD2E9448449|rigid:vxufMYEfF3yv/hxJ0HlG7+0KsJw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06689 uniprotkb:P53283 intact:EBI-38659|uniprotkb:D6VZ50|ensemblfungi:YLR413W intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:yl413_yeast(display_long)|uniprotkb:YLR413W(locus name) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337141|imex:IM-14275-2110 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013517.1|sgd:S000004405|mint:Q06689|dip:DIP-5075N|ensemblfungi:YLR413W(gene)|ensemblfungi:YLR413W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0071944"(cell periphery)|interpro:IPR009571(SUR7) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:92E23436DC857E95 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AoTGKjLhw0NECrtuftZqLANonds559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 intact-crc:5FC83CEF5F37BAD3|rigid:owMyRX5p6DcvG7OUDkyJDkho738 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P53283 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337152|imex:IM-14275-2111 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 intact-crc:C363A1FF4603E984|rigid:tHTGHUQbq7hysft1C2k4coyByLI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07824 uniprotkb:P53283 intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337163|imex:IM-14275-2112 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 intact-crc:3DCD952E653AF083|rigid:QkeivW8+FtIuFFeLzVbUOt30soI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53290 uniprotkb:P53191 intact:EBI-7962|uniprotkb:D6VUU7|ensemblfungi:YGR163W intact:EBI-13400|uniprotkb:E9P8Z2|uniprotkb:D6VUB4|ensemblfungi:YGL023C psi-mi:gtr2_yeast(display_long)|uniprotkb:YGR163W(locus name)|uniprotkb:GTR2(gene name)|psi-mi:GTR2(display_short) psi-mi:pib2_yeast(display_long)|uniprotkb:PIB2(gene name)|psi-mi:PIB2(display_short)|uniprotkb:YGL023C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337174|imex:IM-14275-2113 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003395|refseq:NP_011679.3|mint:P53290|dip:DIP-4521N|ensemblfungi:YGR163W(gene)|ensemblfungi:YGR163W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000785"(chromatin)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039400|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 refseq:NP_011492.3|sgd:S000002991|ensemblfungi:YGL023C(gene)|ensemblfungi:YGL023C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|mint:P53191|dip:DIP-6378N psi-mi:"MI:0469"(intact) crc64:0A0D16C81F73184D crc64:512E9B873E6E0164 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+b9bPvzin/YUc5fOZZVCcFu/GEM559292 rogid:3T1+dWkNV7dfKQf0/9hJkjQbRW4559292 intact-crc:EAB049AC12D7EFB0|rigid:gw54xC1bWxpwd1esn2kJMPhDDbs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53290 uniprotkb:Q02205 intact:EBI-7962|uniprotkb:D6VUU7|ensemblfungi:YGR163W intact:EBI-27062|uniprotkb:D6VX73|ensemblfungi:YKR007W psi-mi:gtr2_yeast(display_long)|uniprotkb:YGR163W(locus name)|uniprotkb:GTR2(gene name)|psi-mi:GTR2(display_short) psi-mi:meh1_yeast(display_long)|uniprotkb:GSE complex subunit 2(gene name synonym)|uniprotkb:EGO complex subunit 1(gene name synonym)|uniprotkb:YKR007W(locus name)|uniprotkb:YK106(orf name)|uniprotkb:MEH1(gene name)|psi-mi:MEH1(display_short)|uniprotkb:EGO1(gene name synonym)|uniprotkb:GSE2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337185|imex:IM-14275-2114 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003395|refseq:NP_011679.3|mint:P53290|dip:DIP-4521N|ensemblfungi:YGR163W(gene)|ensemblfungi:YGR163W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000785"(chromatin)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039400|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 sgd:S000001715|refseq:NP_012932.1|mint:Q02205|dip:DIP-1922N|ensemblfungi:YKR007W(gene)|ensemblfungi:YKR007W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0005829"(cytosol)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007040"(lysosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR028209|rcsb pdb:4XPM|rcsb pdb:6JWP psi-mi:"MI:0469"(intact) crc64:0A0D16C81F73184D crc64:995DD1E68331D050 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+b9bPvzin/YUc5fOZZVCcFu/GEM559292 rogid:73a6e5W5wQixGg2aGXDo4A6NR2s559292 intact-crc:79C0BA88DDE84DCD|rigid:awgzTaC/fJ5bLLQpnTMJa4jMqc8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53295 uniprotkb:P33892 intact:EBI-23421|uniprotkb:D6VUV7|ensemblfungi:YGR173W intact:EBI-7442|uniprotkb:D6VTV8|ensemblfungi:YGL195W psi-mi:rbg2_yeast(display_long)|uniprotkb:YGR173W(locus name)|uniprotkb:RBG2(gene name)|psi-mi:RBG2(display_short)|uniprotkb:GIR1(gene name synonym)|uniprotkb:GTP-binding protein RBG2(gene name synonym) psi-mi:gcn1_yeast(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:General control non-derepressible protein 1(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym)|uniprotkb:G1318(orf name)|uniprotkb:YGL195W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337196|imex:IM-14275-2115 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011689.1|sgd:S000003405|dip:DIP-2827N|mint:P53295|ensemblfungi:YGR173W(gene)|ensemblfungi:YGR173W_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR004095(TGS)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR006074(GTP1/OBG, conserved site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR027417|interpro:IPR031167|interpro:IPR031662|rcsb pdb:7NRC sgd:S000003163|refseq:NP_011320.3|mint:P33892|dip:DIP-2344N|ensemblfungi:YGL195W(gene)|ensemblfungi:YGL195W_mRNA(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071264"(positive regulation of translational initiation in response to starvation)|go:"GO:0072755"(cellular response to benomyl)|go:"GO:0140469"(GCN2-mediated signaling)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1990451"(cellular stress response to acidic pH)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR022716|interpro:IPR033173|interpro:IPR034085 psi-mi:"MI:0469"(intact) crc64:D144569C9C5D777C crc64:980FDD03753E9D1C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mj9ToMhAbXBIJJx7qdX+Vi5qs9g559292 rogid:WPYtEB/xjy4g2cJFwhe+2teVYVk559292 intact-crc:70F5017C215936DF|rigid:YVJxp0QcLwaKNj77Z1AfOI+f1L4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03768 uniprotkb:P53295 intact:EBI-7618|uniprotkb:D6VSD4|ensemblfungi:YDR152W intact:EBI-23421|uniprotkb:D6VUV7|ensemblfungi:YGR173W psi-mi:gir2_yeast(display_long)|uniprotkb:GIR2(gene name)|psi-mi:GIR2(display_short)|uniprotkb:YDR152W(locus name)|uniprotkb:YD8358.08(orf name)|uniprotkb:DFRP2(gene name synonym)|uniprotkb:DRG family-regulatory protein 2(gene name synonym)|uniprotkb:Genetically interacts with ribosomal genes protein 2(gene name synonym) psi-mi:rbg2_yeast(display_long)|uniprotkb:YGR173W(locus name)|uniprotkb:RBG2(gene name)|psi-mi:RBG2(display_short)|uniprotkb:GIR1(gene name synonym)|uniprotkb:GTP-binding protein RBG2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337207|imex:IM-14275-2116 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002559|refseq:NP_010436.3|mint:Q03768|dip:DIP-1751N|ensemblfungi:YDR152W(gene)|ensemblfungi:YDR152W_mRNA(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR006575(RWD)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR040213 refseq:NP_011689.1|sgd:S000003405|dip:DIP-2827N|mint:P53295|ensemblfungi:YGR173W(gene)|ensemblfungi:YGR173W_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR004095(TGS)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR006074(GTP1/OBG, conserved site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR027417|interpro:IPR031167|interpro:IPR031662|rcsb pdb:7NRC psi-mi:"MI:0469"(intact) crc64:CE09A067388638ED crc64:D144569C9C5D777C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2gb8Bf2IGl8RoOmNcIvEMlmgeTE559292 rogid:mj9ToMhAbXBIJJx7qdX+Vi5qs9g559292 intact-crc:9A3F22294299CCE2|rigid:CkRyfkjzyVDmvILPlMqMKDivw5w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53309 uniprotkb:P25623 intact:EBI-23557|uniprotkb:D6VV22|ensemblfungi:YGR241C intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C psi-mi:ap18b_yeast(display_long)|uniprotkb:G8610(orf name)|uniprotkb:YGR241C(locus name)|uniprotkb:YAP1802(gene name)|psi-mi:YAP1802(display_short) psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337218|imex:IM-14275-2117 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011757.3|sgd:S000003473|dip:DIP-2751N|mint:P53309|ensemblfungi:YGR241C(gene)|ensemblfungi:YGR241C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR014712(Clathrin adaptor, phosphoinositide-binding, GAT-like) refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) - crc64:6F35C8F1562E41CC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fbC/HO6axa7TLPJAvYbKc1jlQjQ559292 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 intact-crc:5E228993716D6F09|rigid:NyA1wf8XMoQKM4VvPFKN9g6o6lQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53309 uniprotkb:P32660 intact:EBI-23557|uniprotkb:D6VV22|ensemblfungi:YGR241C intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W psi-mi:ap18b_yeast(display_long)|uniprotkb:G8610(orf name)|uniprotkb:YGR241C(locus name)|uniprotkb:YAP1802(gene name)|psi-mi:YAP1802(display_short) psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337229|imex:IM-14275-2118 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011757.3|sgd:S000003473|dip:DIP-2751N|mint:P53309|ensemblfungi:YGR241C(gene)|ensemblfungi:YGR241C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR014712(Clathrin adaptor, phosphoinositide-binding, GAT-like) sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) psi-mi:"MI:0469"(intact) - crc64:3CC3FBA8ADDE8960 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fbC/HO6axa7TLPJAvYbKc1jlQjQ559292 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 intact-crc:FEE3FB56C5123E98|rigid:9s+Tan6jPls2lUdngQ2vhlqvQOU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53319 uniprotkb:P53319 intact:EBI-1972|uniprotkb:D6VV36|ensemblfungi:YGR256W intact:EBI-1972|uniprotkb:D6VV36|ensemblfungi:YGR256W psi-mi:6pgd2_yeast(display_long)|uniprotkb:GND2(gene name)|psi-mi:GND2(display_short)|uniprotkb:G9170(orf name)|uniprotkb:YGR256W(locus name) psi-mi:6pgd2_yeast(display_long)|uniprotkb:GND2(gene name)|psi-mi:GND2(display_short)|uniprotkb:G9170(orf name)|uniprotkb:YGR256W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337240|imex:IM-14275-2119 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003488|refseq:NP_011772.3|dip:DIP-6605N|mint:P53319|ensemblfungi:YGR256W(gene)|ensemblfungi:YGR256W_mRNA(transcript)|go:"GO:0004616"("phosphogluconate dehydrogenase (decarboxylating) activity")|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009051"(pentose-phosphate shunt, oxidative branch)|go:"GO:0046177"(D-gluconate catabolic process)|go:"GO:0050661"(NADP binding)|interpro:IPR006113(6-phosphogluconate dehydrogenase, decarboxylating)|interpro:IPR006114(6-phosphogluconate dehydrogenase, C-terminal)|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR006183(6-phosphogluconate dehydrogenase)|interpro:IPR006184(6-phosphogluconate-binding site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR036291 sgd:S000003488|refseq:NP_011772.3|dip:DIP-6605N|mint:P53319|ensemblfungi:YGR256W(gene)|ensemblfungi:YGR256W_mRNA(transcript)|go:"GO:0004616"("phosphogluconate dehydrogenase (decarboxylating) activity")|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009051"(pentose-phosphate shunt, oxidative branch)|go:"GO:0046177"(D-gluconate catabolic process)|go:"GO:0050661"(NADP binding)|interpro:IPR006113(6-phosphogluconate dehydrogenase, decarboxylating)|interpro:IPR006114(6-phosphogluconate dehydrogenase, C-terminal)|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR006183(6-phosphogluconate dehydrogenase)|interpro:IPR006184(6-phosphogluconate-binding site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR036291 psi-mi:"MI:0469"(intact) crc64:3D75D53563987735 crc64:3D75D53563987735 figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:KBlf9cuaowCJTDnefOLUjPmasmw559292 rogid:KBlf9cuaowCJTDnefOLUjPmasmw559292 intact-crc:B27EA1E6F37B84EA|rigid:HsqEoWWgpeuxtNQskgk+kUXgHt8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53327 uniprotkb:P36119 intact:EBI-23623|uniprotkb:D6VV48|ensemblfungi:YGR271W intact:EBI-26366|uniprotkb:D6VX88|ensemblfungi:YKR023W psi-mi:slh1_yeast(display_long)|uniprotkb:YGR271W(locus name)|uniprotkb:G9365(orf name)|uniprotkb:SLH1(gene name)|psi-mi:SLH1(display_short)|uniprotkb:SKI2-like helicase 1(gene name synonym)|uniprotkb:Antiviral helicase SLH1(gene name synonym)|uniprotkb:RQT2(gene name synonym) psi-mi:rqt4_yeast(display_long)|uniprotkb:RQT4(gene name)|psi-mi:RQT4(display_short)|uniprotkb:YKR023W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337251|imex:IM-14275-2120 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011787.4|sgd:S000003503|dip:DIP-5563N|mint:P53327|ensemblfungi:YGR271W(gene)|ensemblfungi:YGR271W_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390 sgd:S000001731|refseq:NP_012948.3|mint:P36119|dip:DIP-6275N|ensemblfungi:YKR023W(gene)|ensemblfungi:YKR023W_mRNA(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|interpro:IPR009349(Zinc finger, C2HC5-type)|interpro:IPR039128 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:LlGSM1TXQVNVZcfCvAhmM1hrgDs559292 rogid:Ih0YkCP1ftZGKUv+oUyRsCt1XSo559292 intact-crc:5A527000335AF77B|rigid:lXBVbJ13RwOYMeNq5lUNAmpGmFw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35844 uniprotkb:P53332 intact:EBI-9648|ensemblfungi:YPL145C|uniprotkb:D6W3M4|uniprotkb:E9P8U8 intact:EBI-23648|uniprotkb:D6VV54|ensemblfungi:YGR277C psi-mi:kes1_yeast(display_long)|uniprotkb:KES1(gene name)|psi-mi:KES1(display_short)|uniprotkb:OSH4(gene name synonym)|uniprotkb:Protein KES1(gene name synonym)|uniprotkb:LPI3C(orf name)|uniprotkb:P2614(orf name)|uniprotkb:YPL145C(locus name) psi-mi:coad_yeast(display_long)|uniprotkb:CAB4(gene name)|psi-mi:CAB4(display_short)|uniprotkb:Coenzyme A biosynthesis protein 4(gene name synonym)|uniprotkb:Dephospho-CoA pyrophosphorylase(gene name synonym)|uniprotkb:Pantetheine-phosphate adenylyltransferase(gene name synonym)|uniprotkb:YGR277C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337262|imex:IM-14275-2121 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL145C(gene)|ensemblfungi:YPL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035621"(ER to Golgi ceramide transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|rcsb pdb:1ZHT|rcsb pdb:1ZHW|rcsb pdb:1ZHX|rcsb pdb:1ZHY|rcsb pdb:1ZHZ|rcsb pdb:1ZI7|rcsb pdb:3SPW|rcsb pdb:4F4B|rcsb pdb:4FES|rcsb pdb:4JCH|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_015180.1|sgd:S000006066|dip:DIP-2867N|mint:P35844 refseq:NP_011793.3|sgd:S000003509|dip:DIP-4904N|mint:P53332|ensemblfungi:YGR277C(gene)|ensemblfungi:YGR277C_mRNA(transcript)|go:"GO:0004140"(dephospho-CoA kinase activity)|go:"GO:0004595"(pantetheine-phosphate adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|reactome:R-SCE-196783 psi-mi:"MI:0469"(intact) - crc64:BEB43BEFC54D123C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6vsHrA4RScGr2+xmii0wiuvK1OM559292 rogid:FIzjDDGJ6QcPaPZCof0SJqy3nmY559292 intact-crc:DA22B6251260DBF3|rigid:heqPDN5Q2ljN7Aob260imyv34aE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32495 uniprotkb:P53335 intact:EBI-12014|ensemblfungi:YDL208W|uniprotkb:D6VRE6 intact:EBI-23652|uniprotkb:D6VV57|uniprotkb:Q8TG89|intact:EBI-33325|ensemblfungi:YGR280C psi-mi:nhp2_yeast(display_long)|uniprotkb:NHP2(gene name)|psi-mi:NHP2(display_short)|uniprotkb:YDL208W(locus name)|uniprotkb:D1045(orf name)|uniprotkb:H/ACA snoRNP protein NHP2(gene name synonym)|uniprotkb:High mobility group-like nuclear protein 2(gene name synonym) psi-mi:pxr1_yeast(display_long)|uniprotkb:PXR1(gene name)|psi-mi:PXR1(display_short)|uniprotkb:GNO1(gene name synonym)|uniprotkb:PinX1-related protein 1(gene name synonym)|uniprotkb:G-patch nucleolar protein(gene name synonym)|uniprotkb:YGR280C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337273|imex:IM-14275-2122 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDL208W(gene)|ensemblfungi:YDL208W_mRNA(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000493"(box H/ACA snoRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|rcsb pdb:2LBW|rcsb pdb:2LBX|refseq:NP_010073.2|sgd:S000002367|mint:P32495|dip:DIP-5134N refseq:NP_011796.1|sgd:S000003512|dip:DIP-4308N|mint:P53335|ensemblfungi:YGR280C(gene)|ensemblfungi:YGR280C_mRNA(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|interpro:IPR000467(D111/G-patch) psi-mi:"MI:0469"(intact) crc64:008188132B494E5D crc64:D5AB6EB2C129922D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p5AQTuMF3Vvdu6HWSTYjdjjE1Vs559292 rogid:SzQtp13uvK3KbuNHyZQPJxKMzwY559292 intact-crc:A1DE87F465408A3C|rigid:wyan/1P/Z/F77U3yAcxHrSTLUbA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32583 uniprotkb:P53335 intact:EBI-17992|uniprotkb:D6VXF2|ensemblfungi:YKR092C intact:EBI-23652|uniprotkb:D6VV57|uniprotkb:Q8TG89|intact:EBI-33325|ensemblfungi:YGR280C psi-mi:srp40_yeast(display_long)|uniprotkb:YKR412A(orf name)|uniprotkb:YKR092C(locus name)|uniprotkb:SRP40(gene name)|psi-mi:SRP40(display_short) psi-mi:pxr1_yeast(display_long)|uniprotkb:PXR1(gene name)|psi-mi:PXR1(display_short)|uniprotkb:GNO1(gene name synonym)|uniprotkb:PinX1-related protein 1(gene name synonym)|uniprotkb:G-patch nucleolar protein(gene name synonym)|uniprotkb:YGR280C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337284|imex:IM-14275-2123 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001800|ensemblfungi:YKR092C(gene)|ensemblfungi:YKR092C_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006913"(nucleocytoplasmic transport)|interpro:IPR007718(SRP40, C-terminal)|refseq:NP_013018.3|dip:DIP-2115N|mint:P32583 refseq:NP_011796.1|sgd:S000003512|dip:DIP-4308N|mint:P53335|ensemblfungi:YGR280C(gene)|ensemblfungi:YGR280C_mRNA(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|interpro:IPR000467(D111/G-patch) psi-mi:"MI:0469"(intact) crc64:8EA007695AF4BA1D crc64:D5AB6EB2C129922D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:bk2gXF1o2Rj+ML2zHj1N52chwMc559292 rogid:SzQtp13uvK3KbuNHyZQPJxKMzwY559292 intact-crc:0650E6EFEEEC1F51|rigid:VM+O2FSgjo44ttCJq/zLOs76iSI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53335 uniprotkb:P53335 intact:EBI-23652|uniprotkb:D6VV57|uniprotkb:Q8TG89|intact:EBI-33325|ensemblfungi:YGR280C intact:EBI-23652|uniprotkb:D6VV57|uniprotkb:Q8TG89|intact:EBI-33325|ensemblfungi:YGR280C psi-mi:pxr1_yeast(display_long)|uniprotkb:PXR1(gene name)|psi-mi:PXR1(display_short)|uniprotkb:GNO1(gene name synonym)|uniprotkb:PinX1-related protein 1(gene name synonym)|uniprotkb:G-patch nucleolar protein(gene name synonym)|uniprotkb:YGR280C(locus name) psi-mi:pxr1_yeast(display_long)|uniprotkb:PXR1(gene name)|psi-mi:PXR1(display_short)|uniprotkb:GNO1(gene name synonym)|uniprotkb:PinX1-related protein 1(gene name synonym)|uniprotkb:G-patch nucleolar protein(gene name synonym)|uniprotkb:YGR280C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337295|imex:IM-14275-2124 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011796.1|sgd:S000003512|dip:DIP-4308N|mint:P53335|ensemblfungi:YGR280C(gene)|ensemblfungi:YGR280C_mRNA(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|interpro:IPR000467(D111/G-patch) refseq:NP_011796.1|sgd:S000003512|dip:DIP-4308N|mint:P53335|ensemblfungi:YGR280C(gene)|ensemblfungi:YGR280C_mRNA(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|interpro:IPR000467(D111/G-patch) psi-mi:"MI:0469"(intact) crc64:D5AB6EB2C129922D crc64:D5AB6EB2C129922D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SzQtp13uvK3KbuNHyZQPJxKMzwY559292 rogid:SzQtp13uvK3KbuNHyZQPJxKMzwY559292 intact-crc:C12BB3CE11A3B78A|rigid:EsJRoYREc0+Kb8E1Uxg5M3iKHXE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53335 uniprotkb:Q03525 intact:EBI-23652|uniprotkb:D6VV57|uniprotkb:Q8TG89|intact:EBI-33325|ensemblfungi:YGR280C intact:EBI-27597|uniprotkb:Q7Z870|ensemblfungi:YMR269W|uniprotkb:D6W095 psi-mi:pxr1_yeast(display_long)|uniprotkb:PXR1(gene name)|psi-mi:PXR1(display_short)|uniprotkb:GNO1(gene name synonym)|uniprotkb:PinX1-related protein 1(gene name synonym)|uniprotkb:G-patch nucleolar protein(gene name synonym)|uniprotkb:YGR280C(locus name) psi-mi:tma23_yeast(display_long)|uniprotkb:YMR269W(locus name)|uniprotkb:YM8156.11(orf name)|uniprotkb:TMA23(gene name)|psi-mi:TMA23(display_short)|uniprotkb:YMR268W-A(orf name)|uniprotkb:23 kDa translation machinery-associated protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337306|imex:IM-14275-2125 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011796.1|sgd:S000003512|dip:DIP-4308N|mint:P53335|ensemblfungi:YGR280C(gene)|ensemblfungi:YGR280C_mRNA(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|interpro:IPR000467(D111/G-patch) ensemblfungi:YMR269W(gene)|ensemblfungi:YMR269W_mRNA(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0042274"(ribosomal small subunit biogenesis)|sgd:S000004882|refseq:NP_013996.2|dip:DIP-1965N|mint:Q03525 psi-mi:"MI:0469"(intact) crc64:D5AB6EB2C129922D - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SzQtp13uvK3KbuNHyZQPJxKMzwY559292 rogid:yJy9JnQUnYKqa7aOQ5yEeHcNEpI559292 intact-crc:C65366F87D500158|rigid:LDHv88V2xXPB4vmvAUD9nrYAZCs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6Q547 uniprotkb:P53335 intact:EBI-2052475|uniprotkb:D3DL22|ensemblfungi:YHR072W-A intact:EBI-23652|uniprotkb:D6VV57|uniprotkb:Q8TG89|intact:EBI-33325|ensemblfungi:YGR280C psi-mi:nop10_yeast(display_long)|uniprotkb:YHR072W-A(locus name)|uniprotkb:Nucleolar protein family A member 3(gene name synonym)|uniprotkb:snoRNP protein NOP10(gene name synonym)|uniprotkb:NOP10(gene name)|psi-mi:NOP10(display_short)|uniprotkb:Nucleolar protein 10(gene name synonym) psi-mi:pxr1_yeast(display_long)|uniprotkb:PXR1(gene name)|psi-mi:PXR1(display_short)|uniprotkb:GNO1(gene name synonym)|uniprotkb:PinX1-related protein 1(gene name synonym)|uniprotkb:G-patch nucleolar protein(gene name synonym)|uniprotkb:YGR280C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337317|imex:IM-14275-2126 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058135.1|sgd:S000007455|dip:DIP-5845N|mint:Q6Q547|ensemblfungi:YHR072W-A(gene)|ensemblfungi:YHR072W-A_mRNA(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|interpro:IPR007264(Nucleolar RNA-binding protein Nop10p)|interpro:IPR036756|rcsb pdb:1Y2Y|rcsb pdb:2AQA|rcsb pdb:3U28|rcsb pdb:3UAI refseq:NP_011796.1|sgd:S000003512|dip:DIP-4308N|mint:P53335|ensemblfungi:YGR280C(gene)|ensemblfungi:YGR280C_mRNA(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|interpro:IPR000467(D111/G-patch) psi-mi:"MI:0469"(intact) crc64:4718D35AF7911FBA crc64:D5AB6EB2C129922D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9m0x3DatObFwua2cbCQYMRKGqrU559292 rogid:SzQtp13uvK3KbuNHyZQPJxKMzwY559292 intact-crc:EA2B9038132D7BD6|rigid:1RGPCbx/ndJPD/db+ypV4WsVAVY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P53337 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337328|imex:IM-14275-2127 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 intact-crc:CDFC70A074331195|rigid:WgXf9N7koMQfCAEVbWx+LY+rRIU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:P53337 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337339|imex:IM-14275-2128 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 intact-crc:2727D9C81554BFE8|rigid:4F2Kur/z90QVPz1UsYYE0Z3DAgk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53337 uniprotkb:P26570 intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337350|imex:IM-14275-2129 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N psi-mi:"MI:0469"(intact) - crc64:8B7F009521F72C15 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 intact-crc:554BB3C53957B9C4|rigid:s536f/395uEwak1KeNp24gT4j/M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32500 uniprotkb:P53337 intact:EBI-11950|ensemblfungi:YML031W|uniprotkb:D6VZE3 intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C psi-mi:ndc1_yeast(display_long)|uniprotkb:YML031W(locus name)|uniprotkb:NDC1(gene name)|psi-mi:NDC1(display_short)|uniprotkb:Nuclear pore protein NDC1(gene name synonym)|uniprotkb:Nuclear division cycle protein 1(gene name synonym) psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337361|imex:IM-14275-2130 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML031W(gene)|ensemblfungi:YML031W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0070631"(spindle pole body localization)|go:"GO:0070762"(nuclear pore transmembrane ring)|go:"GO:0106166"(spindle pole body-nuclear membrane anchor activity)|interpro:IPR019049|go:"GO:0017056"(structural constituent of nuclear pore)|refseq:NP_013681.1|sgd:S000004493|mint:P32500|dip:DIP-1465N refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CJawnqL6UYhpSqsKMbif8ifzgUY559292 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 intact-crc:912773CE4765C7FC|rigid:kwb44agDjVGxs8zSE81kzQK/KBU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32915 uniprotkb:P53337 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337372|imex:IM-14275-2131 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 intact-crc:178D7CB80B705904|rigid:ATQ0hobM4NbWdfNWmzUkAZLJ1jw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36076 uniprotkb:P53337 intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short) psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337383|imex:IM-14275-2132 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783 refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Li7vZOassm4PC5fW111/j5ivgEc559292 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 intact-crc:39A4A831D754A0D3|rigid:s4qZoHG1VtUy++DGpQPJz2KxmL4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38353 uniprotkb:P53337 intact:EBI-18175|uniprotkb:D6VQS8|ensemblfungi:YBR283C intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C psi-mi:ssh1_yeast(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:Ssh1 complex subunit alpha(gene name synonym)|uniprotkb:Ssh1 complex subunit SSH1(gene name synonym)|uniprotkb:YBR2020(orf name)|uniprotkb:YBR283C(locus name) psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337394|imex:IM-14275-2133 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009842.1|sgd:S000000487|ensemblfungi:YBR283C(gene)|ensemblfungi:YBR283C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:2WW9|rcsb pdb:2WWA|dip:DIP-4962N|mint:P38353 refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:48267EEA3E0191BD - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:76wvZIdv7W5BQn6wI+sHOGQAyuc559292 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 intact-crc:A2A6136996BC5347|rigid:Wvv9KqCIgInWgb3x6EBwKQhAHds false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38694 uniprotkb:P53337 intact:EBI-24511|uniprotkb:D3DKY6|ensemblfungi:YHR039C intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C psi-mi:msc7_yeast(display_long)|uniprotkb:MSC7(gene name)|psi-mi:MSC7(display_short)|uniprotkb:Meiotic sister-chromatid recombination protein 7(gene name synonym)|uniprotkb:YHR039C(locus name) psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337405|imex:IM-14275-2134 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011904.1|sgd:S000001081|dip:DIP-1878N|mint:P38694|ensemblfungi:YHR039C(gene)|ensemblfungi:YHR039C_mRNA(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007131"(reciprocal meiotic recombination)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510 refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p2xtb6/xYI/jfPNtO6JRZs+5t6I559292 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 intact-crc:2678F67693D8F8B5|rigid:BjNDkXzec9jdEEgl+wvqIgwfcE0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38819 uniprotkb:P53337 intact:EBI-6603|uniprotkb:D3DL60|ensemblfungi:YHR110W intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C psi-mi:erp5_yeast(display_long)|uniprotkb:ERP5(gene name)|psi-mi:ERP5(display_short)|uniprotkb:YHR110W(locus name) psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337416|imex:IM-14275-2135 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011978.1|sgd:S000001152|mint:P38819|dip:DIP-7586N|ensemblfungi:YHR110W(gene)|ensemblfungi:YHR110W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dxo+Sd/z45fHXllQ80yOOxm19jE559292 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 intact-crc:F168B845155E6BF4|rigid:gcouK1V1rDnlY7dDoF9STa9UJpE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40540 uniprotkb:P53337 intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337427|imex:IM-14275-2136 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:6DBEEEE7722203B0 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 intact-crc:2962D6E0729028F8|rigid:B4ZDZTuk1L6FDx9ZaAQDLLbAn5Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53337 uniprotkb:P40582 intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C intact:EBI-7941|uniprotkb:D6VVW9|ensemblfungi:YIR038C psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:gst1_yeast(display_long)|uniprotkb:YIR038C(locus name)|uniprotkb:GTT1(gene name)|psi-mi:GTT1(display_short)|uniprotkb:GST-I(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337438|imex:IM-14275-2137 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 refseq:NP_012304.1|sgd:S000001477|mint:P40582|dip:DIP-2103N|ensemblfungi:YIR038C(gene)|ensemblfungi:YIR038C_mRNA(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010731"(protein glutathionylation)|go:"GO:0071944"(cell periphery)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079 psi-mi:"MI:0469"(intact) - crc64:3C07D40D29F60DFF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 rogid:+bqzHpsoLw4j2qQBzHbkfldR5OU559292 intact-crc:3DEED6E93F7D32DF|rigid:DBOscu7c0W7EPSX/HVRpe+/5Fpw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53337 uniprotkb:P43621 intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C intact:EBI-4876|uniprotkb:D6VTT4|ensemblfungi:YFR051C psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:copd_yeast(display_long)|uniprotkb:RET2(gene name)|psi-mi:RET2(display_short)|uniprotkb:YFR051C(locus name)|uniprotkb:Delta-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337449|imex:IM-14275-2138 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 sgd:S000001947|refseq:NP_116709.3|dip:DIP-5255N|mint:P43621|ensemblfungi:YFR051C(gene)|ensemblfungi:YFR051C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|rcsb pdb:5FJW|rcsb pdb:5FJX|rcsb pdb:5FJZ|rcsb pdb:5FK0|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - crc64:AA730F046655EE5A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 rogid:auvjuT8ffm1R4P3mRKEIWAsynW0559292 intact-crc:CE164447D46B6FA6|rigid:3zv14u9J+DPlfn8Z2TLOP2OvAEw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53337 uniprotkb:P53337 intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337460|imex:IM-14275-2139 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 intact-crc:4C59A58B20B83BA7|rigid:MP1V9REsUj2xuxAjYjFYqwRwG38 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53337 uniprotkb:P54837 intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337471|imex:IM-14275-2140 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:E91C0E164BD288E0|rigid:93TNdlDFpZ91mQa/dG38B3Vh6oo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04651 uniprotkb:P53337 intact:EBI-27850|uniprotkb:E9PAD9|uniprotkb:D6VZA6|ensemblfungi:YML067C intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C psi-mi:erv41_yeast(display_long)|uniprotkb:YML067C(locus name)|uniprotkb:ERV41(gene name)|psi-mi:ERV41(display_short) psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337482|imex:IM-14275-2141 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013644.1|sgd:S000004532|dip:DIP-6791N|mint:Q04651|ensemblfungi:YML067C(gene)|ensemblfungi:YML067C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|rcsb pdb:3ZLC refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IpGpvBxckHz1ExXTnTsKEHU2su8559292 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 intact-crc:B3E631DD50D019F1|rigid:Y4ZfZ9RlXg0JXbnn1RypklykYPE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53337 uniprotkb:Q05359 intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337493|imex:IM-14275-2142 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 intact-crc:F3851A3EE1C77F56|rigid:AtfNIe+OVzx84T+BjkIRs3vosi8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12450 uniprotkb:P53337 intact:EBI-6598|uniprotkb:D6W282|ensemblfungi:YOR016C intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C psi-mi:erp4_yeast(display_long)|uniprotkb:ERP4(gene name)|psi-mi:ERP4(display_short)|uniprotkb:YOR016C(locus name) psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337504|imex:IM-14275-2143 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014659.1|sgd:S000005542|mint:Q12450|dip:DIP-7868N|ensemblfungi:YOR016C(gene)|ensemblfungi:YOR016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|reactome:R-SCE-6811434 refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:An7as6LjEDUYrLvEbua3xSL6bEk559292 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 intact-crc:C291DFC9AAEBD3B7|rigid:BiSt65AWgN5pCVktH6D5gAX0VnE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53337 uniprotkb:Q99287 intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C intact:EBI-37523|uniprotkb:D6W2M3|ensemblfungi:YOR165W psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:sey1_yeast(display_long)|uniprotkb:SEY1(gene name)|psi-mi:SEY1(display_short)|uniprotkb:YOR165W(locus name)|uniprotkb:Synthetic enhancer of YOP1 protein(gene name synonym)|uniprotkb:O3590(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337515|imex:IM-14275-2144 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 refseq:NP_014808.1|sgd:S000005691|dip:DIP-49373N|mint:Q99287|ensemblfungi:YOR165W(gene)|ensemblfungi:YOR165W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0061024"(membrane organization)|go:"GO:0071944"(cell periphery)|interpro:IPR008803(Root hair defective 3 GTP-binding)|interpro:IPR027417|interpro:IPR030386 psi-mi:"MI:0469"(intact) - crc64:DEC0C9EC3AB172DF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 rogid:zFsgalfyUvAuuV51vChJjraiQmI559292 intact-crc:E3C3394418E31185|rigid:/dSKRLvs9FQ681dfRt+tztPoi5o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:P53388 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337526|imex:IM-14275-2145 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) psi-mi:"MI:0469"(intact) - crc64:488A382656039D0B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 intact-crc:B876C1433A14525D|rigid:krGLSCkzfjMMUuedd/CxqOczl9U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53388 uniprotkb:P32465 intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337537|imex:IM-14275-2146 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N psi-mi:"MI:0469"(intact) crc64:488A382656039D0B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 intact-crc:A379FA3F995F4187|rigid:B1I51L+bDyUkFCUovafhWIvjlZg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53388 uniprotkb:P32487 intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W intact:EBI-10258|uniprotkb:D6W0S6|ensemblfungi:YNL268W psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:lyp1_yeast(display_long)|uniprotkb:LYP1(gene name)|psi-mi:LYP1(display_short)|uniprotkb:N0790(orf name)|uniprotkb:YNL268W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337548|imex:IM-14275-2147 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region)|refseq:NP_014131.1|sgd:S000005212|ensemblfungi:YNL268W(gene)|ensemblfungi:YNL268W_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005739"(mitochondrion)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015174"(basic amino acid transmembrane transporter activity)|go:"GO:0015802"(basic amino acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032126"(eisosome)|mint:P32487 psi-mi:"MI:0469"(intact) crc64:488A382656039D0B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 rogid:54NWGujHb25P5sWLEHSOC6ytuG4559292 intact-crc:6937FA36DDC8A890|rigid:eViPJfls3W0bAid0EP8PYQMPYn0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33302 uniprotkb:P53388 intact:EBI-13038|uniprotkb:D6W2L0|ensemblfungi:YOR153W intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W psi-mi:pdr5_yeast(display_long)|uniprotkb:PDR5(gene name)|psi-mi:PDR5(display_short)|uniprotkb:LEM1(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 5(gene name synonym)|uniprotkb:Suppressor of toxicity of sporidesmin(gene name synonym)|uniprotkb:YOR153W(locus name) psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337559|imex:IM-14275-2148 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005679|refseq:NP_014796.3|mint:P33302|dip:DIP-6776N|ensemblfungi:YOR153W(gene)|ensemblfungi:YOR153W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR029481|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926 refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) psi-mi:"MI:0469"(intact) - crc64:488A382656039D0B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sd6SJWf6B0rDZnLVaPHyvr4lhew559292 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 intact-crc:824D3241B0A3ABC9|rigid:Q7IwHHl7e176B3YpBFl+TuFsFE4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53388 uniprotkb:P38084 intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W intact:EBI-3414|uniprotkb:D6VQ67|ensemblfungi:YBR068C psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:bap2_yeast(display_long)|uniprotkb:Branched-chain amino-acid permease 2(gene name synonym)|uniprotkb:BAP2(gene name)|psi-mi:BAP2(display_short)|uniprotkb:YBR068C(locus name)|uniprotkb:YBR0629(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337570|imex:IM-14275-2149 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) sgd:S000000272|refseq:NP_009624.4|dip:DIP-4910N|mint:P38084|ensemblfungi:YBR068C(gene)|ensemblfungi:YBR068C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015192"(L-phenylalanine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098713"(leucine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) psi-mi:"MI:0469"(intact) crc64:488A382656039D0B crc64:B87FD6A7464E07F5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 rogid:7Fw7+M5mBikZBztHE2tSDpvBi/M559292 intact-crc:1580DBF11A50D921|rigid:WIQJoaVYUog2QkvI3eDhi0Hs1tc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P53388 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337581|imex:IM-14275-2150 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) psi-mi:"MI:0469"(intact) - crc64:488A382656039D0B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 intact-crc:F30A64931C7316AD|rigid:3RwxhaITToA059RVH8Jb8BvcvHo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53388 uniprotkb:P53283 intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337592|imex:IM-14275-2151 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:488A382656039D0B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 intact-crc:872655266E35422B|rigid:f9mBvznEzXLFu0mlkvlW5hQiKWE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53388 uniprotkb:P53388 intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337603|imex:IM-14275-2152 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) psi-mi:"MI:0469"(intact) crc64:488A382656039D0B crc64:488A382656039D0B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 intact-crc:C308CE365C1AA10A|rigid:8m9B2pdEDcBxeHsapa+fQzUm4gM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53388 uniprotkb:Q02774 intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337614|imex:IM-14275-2153 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 psi-mi:"MI:0469"(intact) crc64:488A382656039D0B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 intact-crc:9B7DDEE7C22E6AD6|rigid:/cwrODEMdKTI9X9+pi2rJyzYbdQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53388 uniprotkb:Q02785 intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337625|imex:IM-14275-2154 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) crc64:488A382656039D0B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:08A732A9240C5BEB|rigid:LGeD4XwX+KWC/KzeGpDoVQl02Ew false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53390 uniprotkb:P10823 intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337636|imex:IM-14275-2155 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) crc64:2309338F36D96258 crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:0C2AB7D2CF0FE7CA|rigid:L4jBysHxaG2e3xJOVn1+jC5g/gM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:P53390 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337647|imex:IM-14275-2156 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N psi-mi:"MI:0469"(intact) - crc64:2309338F36D96258 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 intact-crc:24E12179339354A4|rigid:Uw8o74Vo272mcoaBAdMpSXW0b1M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53390 uniprotkb:P26570 intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337658|imex:IM-14275-2157 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N psi-mi:"MI:0469"(intact) crc64:2309338F36D96258 crc64:8B7F009521F72C15 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 intact-crc:E3263AA8BDFE6824|rigid:76EFwEU6H+GcxOdkf43RY+Cbq5c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53390 uniprotkb:P33413 intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 intact:EBI-2060312|uniprotkb:D3DKP5|ensemblfungi:YHL016C psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:dur3_yeast(display_long)|uniprotkb:DUR3(gene name)|psi-mi:DUR3(display_short)|uniprotkb:YHL016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337669|imex:IM-14275-2158 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N interpro:IPR031155|refseq:NP_011847.1|sgd:S000001008|interpro:IPR001734(Na+/solute symporter)|interpro:IPR038377|mint:P33413|ensemblfungi:YHL016C(gene)|ensemblfungi:YHL016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0015204"(urea transmembrane transporter activity)|go:"GO:0015489"(putrescine transmembrane transporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015840"(urea transport)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) crc64:2309338F36D96258 - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 rogid:oTFsdtOngA3q5wCbhK/fpVlIsz0559292 intact-crc:C837F7AF00FF7E86|rigid:XN9VOCTLq2BrrhrgLkrTiG40FXc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:P53390 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337680|imex:IM-14275-2159 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N psi-mi:"MI:0469"(intact) - crc64:2309338F36D96258 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 intact-crc:EC2C2388F8CC7688|rigid:jthzbInmU14k8SJmMSX4APiXR0Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38234 uniprotkb:P53390 intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337691|imex:IM-14275-2160 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N psi-mi:"MI:0469"(intact) - crc64:2309338F36D96258 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 intact-crc:0E62F9CB3BF2E341|rigid:DqDU+b+KqrQL64RVObkak2ZNzaQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53390 uniprotkb:P38695 intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337702|imex:IM-14275-2161 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N psi-mi:"MI:0469"(intact) crc64:2309338F36D96258 crc64:6906721BAC1A5F87 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 intact-crc:91157F1FAA08B117|rigid:s3qWprb10j0XGZIEylozeVZ9K80 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40260 uniprotkb:P53390 intact:EBI-10714|ensemblfungi:YGR121C|uniprotkb:D6VUQ2 intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 psi-mi:mep1_yeast(display_long)|uniprotkb:MEP1(gene name)|psi-mi:MEP1(display_short)|uniprotkb:YGR121C(locus name)|uniprotkb:G6331(orf name)|uniprotkb:AMT1(gene name synonym) psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337713|imex:IM-14275-2162 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR121C(gene)|ensemblfungi:YGR121C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|sgd:S000003353|refseq:NP_011636.3|mint:P40260|dip:DIP-5530N refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N psi-mi:"MI:0469"(intact) - crc64:2309338F36D96258 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VnoBl5jhQD24N0SbCLv68HCwl1U559292 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 intact-crc:F9417A5DFF5C3844|rigid:O/pzYx4h6t3Hrvh/1WrZd98IUwA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P53390 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337724|imex:IM-14275-2163 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N psi-mi:"MI:0469"(intact) - crc64:2309338F36D96258 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 intact-crc:6F9D84A915F41054|rigid:/JcYyA91GpwGyCnu5u/SHuegZqA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53390 uniprotkb:P53049 intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337735|imex:IM-14275-2164 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 psi-mi:"MI:0469"(intact) crc64:2309338F36D96258 - figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 intact-crc:2AEF4450C19AE616|rigid:PPLerixzhvSR8/u+6ms1ti/TTaU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53390 uniprotkb:P53390 intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337746|imex:IM-14275-2165 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N psi-mi:"MI:0469"(intact) crc64:2309338F36D96258 crc64:2309338F36D96258 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 intact-crc:38FE2E29BAEC1C7B|rigid:yvk6abdFLiwkwBay9mVaCn8yo6I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53390 uniprotkb:Q02785 intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337757|imex:IM-14275-2166 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) crc64:2309338F36D96258 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:6FC6328CCB7DE063|rigid:LdMhvecIHcTskZ3iFLONhhanTKE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:P53390 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337768|imex:IM-14275-2167 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 crc64:2309338F36D96258 figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 intact-crc:21F144C162CDB73E|rigid:/D0ltj1q+0UX6AKoBZXFnqVM1uU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06689 uniprotkb:P53390 intact:EBI-38659|uniprotkb:D6VZ50|ensemblfungi:YLR413W intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 psi-mi:yl413_yeast(display_long)|uniprotkb:YLR413W(locus name) psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337779|imex:IM-14275-2168 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013517.1|sgd:S000004405|mint:Q06689|dip:DIP-5075N|ensemblfungi:YLR413W(gene)|ensemblfungi:YLR413W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0071944"(cell periphery)|interpro:IPR009571(SUR7) refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N psi-mi:"MI:0469"(intact) crc64:92E23436DC857E95 crc64:2309338F36D96258 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AoTGKjLhw0NECrtuftZqLANonds559292 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 intact-crc:FD465F329C04D6F4|rigid:3/RtMuppwzh8V9aGbKV4Bn1OoI8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53390 uniprotkb:Q07651 intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337790|imex:IM-14275-2169 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) crc64:2309338F36D96258 - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:61EAB392853085A3|rigid:y4J3E6sp4SZTAO5v3u/LfNQbjyg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07824 uniprotkb:P53390 intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337801|imex:IM-14275-2170 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N psi-mi:"MI:0469"(intact) - crc64:2309338F36D96258 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 intact-crc:9F43F423A6099CA4|rigid:WsbFjYVEC6wdTLAWqB4oGtQDUDk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53390 uniprotkb:Q08967 intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 intact:EBI-36673|uniprotkb:D6W3E9|ensemblfungi:YPL221W psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:flc1_yeast(display_long)|uniprotkb:FAD transporter 1(gene name synonym)|uniprotkb:FLC1(gene name)|psi-mi:FLC1(display_short)|uniprotkb:TRP-like ion channel protein FLC1(gene name synonym)|uniprotkb:Heme utilization factor 1(gene name synonym)|uniprotkb:Bypass of PAM1 protein 1(gene name synonym)|uniprotkb:HUF1(gene name synonym)|uniprotkb:YPL221W(locus name)|uniprotkb:BOP1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337812|imex:IM-14275-2171 author score:99.34 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N refseq:NP_015103.1|sgd:S000006142|mint:Q08967|dip:DIP-3965N|ensemblfungi:YPL221W(gene)|ensemblfungi:YPL221W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055085"(transmembrane transport)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241 psi-mi:"MI:0469"(intact) crc64:2309338F36D96258 - figure legend:tables S3 and S4|author-confidence:99.34|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 rogid:r6CcZGEjxHUk2w0iBUBvnAPaFd4559292 intact-crc:D667AC6FBCCC4902|rigid:3n0ncfKmga8Zjxi/1j0nrzTy5ks false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53438 uniprotkb:P07278 intact:EBI-2090670|uniprotkb:D6VZJ0|ensemblfungi:YMR016C intact:EBI-9475|ensemblfungi:YIL033C|uniprotkb:D6VVP9 psi-mi:sok2_yeast(display_long)|uniprotkb:YM9711.03C(orf name)|uniprotkb:YMR016C(locus name)|uniprotkb:SOK2(gene name)|psi-mi:SOK2(display_short) psi-mi:kapr_yeast(display_long)|uniprotkb:YIL033C(locus name)|uniprotkb:BCY1(gene name)|psi-mi:BCY1(display_short)|uniprotkb:REG1(gene name synonym)|uniprotkb:SRA1(gene name synonym)|uniprotkb:Bypass of cyclase mutations protein 1(gene name synonym)|uniprotkb:Protein kinase A regulatory subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337823|imex:IM-14275-2172 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029790|interpro:IPR018004|refseq:NP_013729.1|sgd:S000004618|interpro:IPR003163(DNA-binding, yeast)|mint:P53438|interpro:IPR036887|ensemblfungi:YMR016C(gene)|ensemblfungi:YMR016C_mRNA(transcript)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II) ensemblfungi:YIL033C(gene)|ensemblfungi:YIL033C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0030552"(cAMP binding)|go:"GO:0036278"(positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0061406"(positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|rcsb pdb:3OF1|rcsb pdb:6XQK|refseq:NP_012231.1|sgd:S000001295|mint:P07278|dip:DIP-551N psi-mi:"MI:0469"(intact) - crc64:6D7D97D8E4340AF3 figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:PmmMgzX2bxAARzNtHvolvT8QZPY559292 rogid:rSJ37UFoFiaHqc/2W5eYNx1qpbg559292 intact-crc:7815B7C3FF39DDC8|rigid:tJxQDrthGBT63Fy69+vSemSbQqE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53550 uniprotkb:P25644 intact:EBI-270|uniprotkb:B0KZS6|uniprotkb:B0KZU4|uniprotkb:B0KZW2|uniprotkb:B0KZY0|uniprotkb:B0KZY9|uniprotkb:B0KZZ8|uniprotkb:B0L007|uniprotkb:Q6LCS6|uniprotkb:D6W164|ensemblfungi:YNL118C intact:EBI-204|uniprotkb:Q8NKJ3|uniprotkb:D6VR80|ensemblfungi:YCR077C psi-mi:dcp2_yeast(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:Protein PSU1(gene name synonym)|uniprotkb:PSU1(gene name synonym)|uniprotkb:mRNA-decapping enzyme subunit 2(gene name synonym)|uniprotkb:N1917(orf name)|uniprotkb:YNL118C(locus name) psi-mi:pat1_yeast(display_long)|uniprotkb:PAT1(gene name)|psi-mi:PAT1(display_short)|uniprotkb:Decapping activator and translational repressor PAT1(gene name synonym)|uniprotkb:mRNA turnover protein 1(gene name synonym)|uniprotkb:MRT1(gene name synonym)|uniprotkb:Topoisomerase II-associated protein PAT1(gene name synonym)|uniprotkb:YCR77C(orf name)|uniprotkb:YCR077C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337834|imex:IM-14275-2173 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014281.1|sgd:S000005062|mint:P53550|dip:DIP-969N|ensemblfungi:YNL118C(gene)|ensemblfungi:YNL118C_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0034063"(stress granule assembly)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0098745"(Dcp1-Dcp2 complex)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:2JVB|rcsb pdb:4K6E|rcsb pdb:4KG3|rcsb pdb:4KG4|rcsb pdb:5LM5|rcsb pdb:5LMF|rcsb pdb:5LMG|rcsb pdb:6Y3Z|reactome:R-SCE-430039|reactome:R-SCE-450385|reactome:R-SCE-450513 refseq:NP_010002.3|sgd:S000000673|mint:P25644|dip:DIP-883N|ensemblfungi:YCR077C(gene)|ensemblfungi:YCR077C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000776"(kinetochore)|go:"GO:0000932"(P-body)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033962"(P-body assembly)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0051301"(cell division)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR019167|interpro:IPR039900|rcsb pdb:4BRW|rcsb pdb:4C8Q|rcsb pdb:4N0A|rcsb pdb:4OGP|rcsb pdb:4OJJ|rcsb pdb:5LM5|rcsb pdb:5LMF|rcsb pdb:5LMG|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:D53CA2C5A546FA4A crc64:2DBE1210C173E468 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ER6Kq15/LioWZN7Rw1kAVESWAss559292 rogid:kov8R0RAgIOPffQ7ydjCUxjoE/M559292 intact-crc:4FD3472AD6BEE67B|rigid:2lga2vol/HOcUt9US8fTHVOnO2E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53550 uniprotkb:P30771 intact:EBI-270|uniprotkb:B0KZS6|uniprotkb:B0KZU4|uniprotkb:B0KZW2|uniprotkb:B0KZY0|uniprotkb:B0KZY9|uniprotkb:B0KZZ8|uniprotkb:B0L007|uniprotkb:Q6LCS6|uniprotkb:D6W164|ensemblfungi:YNL118C intact:EBI-11831|ensemblfungi:YMR080C|uniprotkb:D6VZQ4 psi-mi:dcp2_yeast(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:Protein PSU1(gene name synonym)|uniprotkb:PSU1(gene name synonym)|uniprotkb:mRNA-decapping enzyme subunit 2(gene name synonym)|uniprotkb:N1917(orf name)|uniprotkb:YNL118C(locus name) psi-mi:nam7_yeast(display_long)|uniprotkb:NAM7(gene name)|psi-mi:NAM7(display_short)|uniprotkb:IFS2(gene name synonym)|uniprotkb:MOF4(gene name synonym)|uniprotkb:Nonsense-mediated mRNA decay protein 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1(gene name synonym)|uniprotkb:UPF1(gene name synonym)|uniprotkb:YM9582.05C(orf name)|uniprotkb:YMR080C(locus name)|uniprotkb:Nuclear accommodation of mitochondria 7 protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337845|imex:IM-14275-2174 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014281.1|sgd:S000005062|mint:P53550|dip:DIP-969N|ensemblfungi:YNL118C(gene)|ensemblfungi:YNL118C_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0034063"(stress granule assembly)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0098745"(Dcp1-Dcp2 complex)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:2JVB|rcsb pdb:4K6E|rcsb pdb:4KG3|rcsb pdb:4KG4|rcsb pdb:5LM5|rcsb pdb:5LMF|rcsb pdb:5LMG|rcsb pdb:6Y3Z|reactome:R-SCE-430039|reactome:R-SCE-450385|reactome:R-SCE-450513 ensemblfungi:YMR080C(gene)|ensemblfungi:YMR080C_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006310"(DNA recombination)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|rcsb pdb:2XZL|reactome:R-SCE-975956|reactome:R-SCE-975957|go:"GO:0003729"(mRNA binding)|refseq:NP_013797.1|sgd:S000004685|dip:DIP-2373N|mint:P30771 psi-mi:"MI:0469"(intact) crc64:D53CA2C5A546FA4A crc64:9161AFB0BE6747FE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ER6Kq15/LioWZN7Rw1kAVESWAss559292 rogid:f+dpOF+VBHbkicUTBu2HejagP2s559292 intact-crc:00278A36F2E23EAC|rigid:BcNwohwSKayLs8PnGdjlHmbEYcg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35732 uniprotkb:P53550 intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C intact:EBI-270|uniprotkb:B0KZS6|uniprotkb:B0KZU4|uniprotkb:B0KZW2|uniprotkb:B0KZY0|uniprotkb:B0KZY9|uniprotkb:B0KZZ8|uniprotkb:B0L007|uniprotkb:Q6LCS6|uniprotkb:D6W164|ensemblfungi:YNL118C psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:dcp2_yeast(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:Protein PSU1(gene name synonym)|uniprotkb:PSU1(gene name synonym)|uniprotkb:mRNA-decapping enzyme subunit 2(gene name synonym)|uniprotkb:N1917(orf name)|uniprotkb:YNL118C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337856|imex:IM-14275-2175 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 refseq:NP_014281.1|sgd:S000005062|mint:P53550|dip:DIP-969N|ensemblfungi:YNL118C(gene)|ensemblfungi:YNL118C_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0034063"(stress granule assembly)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0098745"(Dcp1-Dcp2 complex)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:2JVB|rcsb pdb:4K6E|rcsb pdb:4KG3|rcsb pdb:4KG4|rcsb pdb:5LM5|rcsb pdb:5LMF|rcsb pdb:5LMG|rcsb pdb:6Y3Z|reactome:R-SCE-430039|reactome:R-SCE-450385|reactome:R-SCE-450513 psi-mi:"MI:0469"(intact) crc64:05734E2D0B7389AC crc64:D53CA2C5A546FA4A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 rogid:ER6Kq15/LioWZN7Rw1kAVESWAss559292 intact-crc:C4A6D8DE279D6643|rigid:LJDzCeEZP61EGMy4iWXATpKRLmU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53550 uniprotkb:P39517 intact:EBI-270|uniprotkb:B0KZS6|uniprotkb:B0KZU4|uniprotkb:B0KZW2|uniprotkb:B0KZY0|uniprotkb:B0KZY9|uniprotkb:B0KZZ8|uniprotkb:B0L007|uniprotkb:Q6LCS6|uniprotkb:D6W164|ensemblfungi:YNL118C intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C psi-mi:dcp2_yeast(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:Protein PSU1(gene name synonym)|uniprotkb:PSU1(gene name synonym)|uniprotkb:mRNA-decapping enzyme subunit 2(gene name synonym)|uniprotkb:N1917(orf name)|uniprotkb:YNL118C(locus name) psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337867|imex:IM-14275-2176 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014281.1|sgd:S000005062|mint:P53550|dip:DIP-969N|ensemblfungi:YNL118C(gene)|ensemblfungi:YNL118C_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0034063"(stress granule assembly)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0098745"(Dcp1-Dcp2 complex)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:2JVB|rcsb pdb:4K6E|rcsb pdb:4KG3|rcsb pdb:4KG4|rcsb pdb:5LM5|rcsb pdb:5LMF|rcsb pdb:5LMG|rcsb pdb:6Y3Z|reactome:R-SCE-430039|reactome:R-SCE-450385|reactome:R-SCE-450513 sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:D53CA2C5A546FA4A crc64:062CFA56DF6F2CEE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ER6Kq15/LioWZN7Rw1kAVESWAss559292 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 intact-crc:0AB6DC44667121D4|rigid:1GAHlf9VFLt/qKL7KqzxZTFdhtc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53550 uniprotkb:P39998 intact:EBI-270|uniprotkb:B0KZS6|uniprotkb:B0KZU4|uniprotkb:B0KZW2|uniprotkb:B0KZY0|uniprotkb:B0KZY9|uniprotkb:B0KZZ8|uniprotkb:B0L007|uniprotkb:Q6LCS6|uniprotkb:D6W164|ensemblfungi:YNL118C intact:EBI-22300|uniprotkb:D3DLN5|ensemblfungi:YEL015W psi-mi:dcp2_yeast(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:Protein PSU1(gene name synonym)|uniprotkb:PSU1(gene name synonym)|uniprotkb:mRNA-decapping enzyme subunit 2(gene name synonym)|uniprotkb:N1917(orf name)|uniprotkb:YNL118C(locus name) psi-mi:edc3_yeast(display_long)|uniprotkb:EDC3(gene name)|psi-mi:EDC3(display_short)|uniprotkb:LSM16(gene name synonym)|uniprotkb:YEL015W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337878|imex:IM-14275-2177 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014281.1|sgd:S000005062|mint:P53550|dip:DIP-969N|ensemblfungi:YNL118C(gene)|ensemblfungi:YNL118C_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0034063"(stress granule assembly)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0098745"(Dcp1-Dcp2 complex)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:2JVB|rcsb pdb:4K6E|rcsb pdb:4KG3|rcsb pdb:4KG4|rcsb pdb:5LM5|rcsb pdb:5LMF|rcsb pdb:5LMG|rcsb pdb:6Y3Z|reactome:R-SCE-430039|reactome:R-SCE-450385|reactome:R-SCE-450513 refseq:NP_010901.1|sgd:S000000741|dip:DIP-842N|mint:P39998|ensemblfungi:YEL015W(gene)|ensemblfungi:YEL015W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0033962"(P-body assembly)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR019050|interpro:IPR025762|interpro:IPR036652|rcsb pdb:4BRU|rcsb pdb:6Y3Z|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:D53CA2C5A546FA4A crc64:BF28AE67F9303A73 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ER6Kq15/LioWZN7Rw1kAVESWAss559292 rogid:6NZRCnakEXzFmlF+UujC024p1GE559292 intact-crc:F278507E9A0DF8E2|rigid:ZGtFMXlYGv/aWTXmORieZrL8uLk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40023 uniprotkb:P53550 intact:EBI-22493|uniprotkb:D3DLT4|ensemblfungi:YER035W intact:EBI-270|uniprotkb:B0KZS6|uniprotkb:B0KZU4|uniprotkb:B0KZW2|uniprotkb:B0KZY0|uniprotkb:B0KZY9|uniprotkb:B0KZZ8|uniprotkb:B0L007|uniprotkb:Q6LCS6|uniprotkb:D6W164|ensemblfungi:YNL118C psi-mi:edc2_yeast(display_long)|uniprotkb:YER035W(locus name)|uniprotkb:EDC2(gene name)|psi-mi:EDC2(display_short) psi-mi:dcp2_yeast(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:Protein PSU1(gene name synonym)|uniprotkb:PSU1(gene name synonym)|uniprotkb:mRNA-decapping enzyme subunit 2(gene name synonym)|uniprotkb:N1917(orf name)|uniprotkb:YNL118C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337889|imex:IM-14275-2178 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000837|refseq:NP_010952.3|dip:DIP-5234N|mint:P40023|ensemblfungi:YER035W(gene)|ensemblfungi:YER035W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0032056"(positive regulation of translation in response to stress) refseq:NP_014281.1|sgd:S000005062|mint:P53550|dip:DIP-969N|ensemblfungi:YNL118C(gene)|ensemblfungi:YNL118C_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0034063"(stress granule assembly)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0098745"(Dcp1-Dcp2 complex)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:2JVB|rcsb pdb:4K6E|rcsb pdb:4KG3|rcsb pdb:4KG4|rcsb pdb:5LM5|rcsb pdb:5LMF|rcsb pdb:5LMG|rcsb pdb:6Y3Z|reactome:R-SCE-430039|reactome:R-SCE-450385|reactome:R-SCE-450513 psi-mi:"MI:0469"(intact) crc64:4D8A461EFD78BFA9 crc64:D53CA2C5A546FA4A figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nW5oKJQ2vCy2/EmFSke5vZAK/3U559292 rogid:ER6Kq15/LioWZN7Rw1kAVESWAss559292 intact-crc:F672D6D3B946A3A2|rigid:7u8kPvQUNBCxVkC4VijybehG+90 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53550 uniprotkb:P40070 intact:EBI-270|uniprotkb:B0KZS6|uniprotkb:B0KZU4|uniprotkb:B0KZW2|uniprotkb:B0KZY0|uniprotkb:B0KZY9|uniprotkb:B0KZZ8|uniprotkb:B0L007|uniprotkb:Q6LCS6|uniprotkb:D6W164|ensemblfungi:YNL118C intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W psi-mi:dcp2_yeast(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:Protein PSU1(gene name synonym)|uniprotkb:PSU1(gene name synonym)|uniprotkb:mRNA-decapping enzyme subunit 2(gene name synonym)|uniprotkb:N1917(orf name)|uniprotkb:YNL118C(locus name) psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337900|imex:IM-14275-2179 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014281.1|sgd:S000005062|mint:P53550|dip:DIP-969N|ensemblfungi:YNL118C(gene)|ensemblfungi:YNL118C_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0034063"(stress granule assembly)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0098745"(Dcp1-Dcp2 complex)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:2JVB|rcsb pdb:4K6E|rcsb pdb:4KG3|rcsb pdb:4KG4|rcsb pdb:5LM5|rcsb pdb:5LMF|rcsb pdb:5LMG|rcsb pdb:6Y3Z|reactome:R-SCE-430039|reactome:R-SCE-450385|reactome:R-SCE-450513 sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:D53CA2C5A546FA4A crc64:69CAC1F01D5BFA98 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ER6Kq15/LioWZN7Rw1kAVESWAss559292 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 intact-crc:979A55BE6884949D|rigid:ii7/4SRxQYfxU7tFZFJBt+/8Kgs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53550 uniprotkb:P45978 intact:EBI-270|uniprotkb:B0KZS6|uniprotkb:B0KZU4|uniprotkb:B0KZW2|uniprotkb:B0KZY0|uniprotkb:B0KZY9|uniprotkb:B0KZZ8|uniprotkb:B0L007|uniprotkb:Q6LCS6|uniprotkb:D6W164|ensemblfungi:YNL118C intact:EBI-16691|ensemblfungi:YPR129W|uniprotkb:D6W4C6 psi-mi:dcp2_yeast(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:Protein PSU1(gene name synonym)|uniprotkb:PSU1(gene name synonym)|uniprotkb:mRNA-decapping enzyme subunit 2(gene name synonym)|uniprotkb:N1917(orf name)|uniprotkb:YNL118C(locus name) psi-mi:scd6_yeast(display_long)|uniprotkb:P9659.10(orf name)|uniprotkb:YPR129W(locus name)|uniprotkb:SCD6(gene name)|psi-mi:SCD6(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337911|imex:IM-14275-2180 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014281.1|sgd:S000005062|mint:P53550|dip:DIP-969N|ensemblfungi:YNL118C(gene)|ensemblfungi:YNL118C_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0034063"(stress granule assembly)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0098745"(Dcp1-Dcp2 complex)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:2JVB|rcsb pdb:4K6E|rcsb pdb:4KG3|rcsb pdb:4KG4|rcsb pdb:5LM5|rcsb pdb:5LMF|rcsb pdb:5LMG|rcsb pdb:6Y3Z|reactome:R-SCE-430039|reactome:R-SCE-450385|reactome:R-SCE-450513 ensemblfungi:YPR129W(gene)|ensemblfungi:YPR129W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:0003729"(mRNA binding)|interpro:IPR025609|refseq:NP_015454.1|sgd:S000006333|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR019050|interpro:IPR025761|interpro:IPR025762|interpro:IPR025768|mint:P45978 psi-mi:"MI:0469"(intact) crc64:D53CA2C5A546FA4A - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ER6Kq15/LioWZN7Rw1kAVESWAss559292 rogid:QRNg1nbLjsxR5twooPvrSPZTWO0559292 intact-crc:2C0B6E7E83691670|rigid:FCzRfIS4WXgJjOwfiIDO+CPyeNM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53550 uniprotkb:P53550 intact:EBI-270|uniprotkb:B0KZS6|uniprotkb:B0KZU4|uniprotkb:B0KZW2|uniprotkb:B0KZY0|uniprotkb:B0KZY9|uniprotkb:B0KZZ8|uniprotkb:B0L007|uniprotkb:Q6LCS6|uniprotkb:D6W164|ensemblfungi:YNL118C intact:EBI-270|uniprotkb:B0KZS6|uniprotkb:B0KZU4|uniprotkb:B0KZW2|uniprotkb:B0KZY0|uniprotkb:B0KZY9|uniprotkb:B0KZZ8|uniprotkb:B0L007|uniprotkb:Q6LCS6|uniprotkb:D6W164|ensemblfungi:YNL118C psi-mi:dcp2_yeast(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:Protein PSU1(gene name synonym)|uniprotkb:PSU1(gene name synonym)|uniprotkb:mRNA-decapping enzyme subunit 2(gene name synonym)|uniprotkb:N1917(orf name)|uniprotkb:YNL118C(locus name) psi-mi:dcp2_yeast(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:Protein PSU1(gene name synonym)|uniprotkb:PSU1(gene name synonym)|uniprotkb:mRNA-decapping enzyme subunit 2(gene name synonym)|uniprotkb:N1917(orf name)|uniprotkb:YNL118C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337922|imex:IM-14275-2181 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014281.1|sgd:S000005062|mint:P53550|dip:DIP-969N|ensemblfungi:YNL118C(gene)|ensemblfungi:YNL118C_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0034063"(stress granule assembly)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0098745"(Dcp1-Dcp2 complex)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:2JVB|rcsb pdb:4K6E|rcsb pdb:4KG3|rcsb pdb:4KG4|rcsb pdb:5LM5|rcsb pdb:5LMF|rcsb pdb:5LMG|rcsb pdb:6Y3Z|reactome:R-SCE-430039|reactome:R-SCE-450385|reactome:R-SCE-450513 refseq:NP_014281.1|sgd:S000005062|mint:P53550|dip:DIP-969N|ensemblfungi:YNL118C(gene)|ensemblfungi:YNL118C_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0034063"(stress granule assembly)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0098745"(Dcp1-Dcp2 complex)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:2JVB|rcsb pdb:4K6E|rcsb pdb:4KG3|rcsb pdb:4KG4|rcsb pdb:5LM5|rcsb pdb:5LMF|rcsb pdb:5LMG|rcsb pdb:6Y3Z|reactome:R-SCE-430039|reactome:R-SCE-450385|reactome:R-SCE-450513 psi-mi:"MI:0469"(intact) crc64:D53CA2C5A546FA4A crc64:D53CA2C5A546FA4A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ER6Kq15/LioWZN7Rw1kAVESWAss559292 rogid:ER6Kq15/LioWZN7Rw1kAVESWAss559292 intact-crc:747585CA1E85167F|rigid:1aNG8ytqYiG/ezRx1eHImJsy1pY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53829 uniprotkb:P53550 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-270|uniprotkb:B0KZS6|uniprotkb:B0KZU4|uniprotkb:B0KZW2|uniprotkb:B0KZY0|uniprotkb:B0KZY9|uniprotkb:B0KZZ8|uniprotkb:B0L007|uniprotkb:Q6LCS6|uniprotkb:D6W164|ensemblfungi:YNL118C psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:dcp2_yeast(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:Protein PSU1(gene name synonym)|uniprotkb:PSU1(gene name synonym)|uniprotkb:mRNA-decapping enzyme subunit 2(gene name synonym)|uniprotkb:N1917(orf name)|uniprotkb:YNL118C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337933|imex:IM-14275-2182 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 refseq:NP_014281.1|sgd:S000005062|mint:P53550|dip:DIP-969N|ensemblfungi:YNL118C(gene)|ensemblfungi:YNL118C_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0034063"(stress granule assembly)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0098745"(Dcp1-Dcp2 complex)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:2JVB|rcsb pdb:4K6E|rcsb pdb:4KG3|rcsb pdb:4KG4|rcsb pdb:5LM5|rcsb pdb:5LMF|rcsb pdb:5LMG|rcsb pdb:6Y3Z|reactome:R-SCE-430039|reactome:R-SCE-450385|reactome:R-SCE-450513 psi-mi:"MI:0469"(intact) crc64:F3DBABE6AD3C7F3C crc64:D53CA2C5A546FA4A figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:ER6Kq15/LioWZN7Rw1kAVESWAss559292 intact-crc:480426A998A5EA90|rigid:E1YXG8cArbTOUVrhBOzX5us1lGo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P57743 uniprotkb:P53550 intact:EBI-10227|uniprotkb:Q05176|uniprotkb:Q06759|uniprotkb:D6VZ73|ensemblfungi:YLR438C-A intact:EBI-270|uniprotkb:B0KZS6|uniprotkb:B0KZU4|uniprotkb:B0KZW2|uniprotkb:B0KZY0|uniprotkb:B0KZY9|uniprotkb:B0KZZ8|uniprotkb:B0L007|uniprotkb:Q6LCS6|uniprotkb:D6W164|ensemblfungi:YNL118C psi-mi:lsm3_yeast(display_long)|uniprotkb:LSM3(gene name)|psi-mi:LSM3(display_short)|uniprotkb:SMX4(gene name synonym)|uniprotkb:USS2(gene name synonym)|uniprotkb:YLR438C-A(locus name)|uniprotkb:SmX4 protein(gene name synonym) psi-mi:dcp2_yeast(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:Protein PSU1(gene name synonym)|uniprotkb:PSU1(gene name synonym)|uniprotkb:mRNA-decapping enzyme subunit 2(gene name synonym)|uniprotkb:N1917(orf name)|uniprotkb:YNL118C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337944|imex:IM-14275-2183 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006434|ensemblfungi:YLR438C-A(gene)|ensemblfungi:YLR438C-A_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034105|interpro:IPR040002|rcsb pdb:3BW1|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:4N0A|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039|rcsb pdb:4M75|refseq:NP_013543.3|dip:DIP-2587N|mint:P57743 refseq:NP_014281.1|sgd:S000005062|mint:P53550|dip:DIP-969N|ensemblfungi:YNL118C(gene)|ensemblfungi:YNL118C_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0034063"(stress granule assembly)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0098745"(Dcp1-Dcp2 complex)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:2JVB|rcsb pdb:4K6E|rcsb pdb:4KG3|rcsb pdb:4KG4|rcsb pdb:5LM5|rcsb pdb:5LMF|rcsb pdb:5LMG|rcsb pdb:6Y3Z|reactome:R-SCE-430039|reactome:R-SCE-450385|reactome:R-SCE-450513 psi-mi:"MI:0469"(intact) crc64:787084EF6A5945B7 crc64:D53CA2C5A546FA4A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nYl7At1SnlSwN+nWr1F1xm0tdDE559292 rogid:ER6Kq15/LioWZN7Rw1kAVESWAss559292 intact-crc:45BEDBA7A4DCD3A3|rigid:7NFSalK8WxC4ULo5/aw7v7G4po8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07084 uniprotkb:P53599 intact:EBI-18184|uniprotkb:Q07909|uniprotkb:D6VY08|ensemblfungi:YLR006C intact:EBI-18191|uniprotkb:D6W1K5|ensemblfungi:YNR031C psi-mi:ssk1_yeast(display_long)|uniprotkb:YLR006C(locus name)|uniprotkb:SSK1(gene name)|psi-mi:SSK1(display_short) psi-mi:ssk2_yeast(display_long)|uniprotkb:SSK2(gene name)|psi-mi:SSK2(display_short)|uniprotkb:YNR031C(locus name)|uniprotkb:N3276(orf name)|uniprotkb:Suppressor of sensor kinase 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337955|imex:IM-14275-2184 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013106.1|sgd:S000003996|ensemblfungi:YLR006C(gene)|ensemblfungi:YLR006C_mRNA(transcript)|go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007234"(osmosensory signaling via phosphorelay pathway)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:1990315"(Mcs4 RR-MAPKKK complex)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|rcsb pdb:5KBX|dip:DIP-2437N|mint:Q07084 refseq:NP_014428.1|sgd:S000005314|ensemblfungi:YNR031C(gene)|ensemblfungi:YNR031C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0003779"(actin binding)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007234"(osmosensory signaling via phosphorelay pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017240(MAP kinase kinase kinase, SSK22)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-389357|dip:DIP-2436N|mint:P53599 psi-mi:"MI:0469"(intact) crc64:33B2DBB4FCF2528A crc64:91A07A195CB3772E figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:xmyX+JrLkDhsvw7i7m+FHfBWmV0559292 rogid:0Syq+NfHfzuqKTtNtN+kjya9ejc559292 intact-crc:72E8F755D4F22C0F|rigid:KWX2d1vAL7BD1mkkRd7N+bstHew false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:P53600 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-4905|uniprotkb:D6W402|ensemblfungi:YPL010W psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:copz_yeast(display_long)|uniprotkb:LPA7W(orf name)|uniprotkb:YP8132.03(orf name)|uniprotkb:RET3(gene name)|psi-mi:RET3(display_short)|uniprotkb:YPL010W(locus name)|uniprotkb:Zeta-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337966|imex:IM-14275-2185 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 refseq:NP_015315.1|sgd:S000005931|dip:DIP-6809N|mint:P53600|ensemblfungi:YPL010W(gene)|ensemblfungi:YPL010W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR039652|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:5xJ9ZinVUq4YB5e92ZexbjmB0rk559292 intact-crc:38FC027AA1498A81|rigid:nFFeukQw98AJzFKvrWrurazKNtc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32074 uniprotkb:P53600 intact:EBI-4891|ensemblfungi:YNL287W|uniprotkb:D6W0Q6 intact:EBI-4905|uniprotkb:D6W402|ensemblfungi:YPL010W psi-mi:copg_yeast(display_long)|uniprotkb:SEC21(gene name)|psi-mi:SEC21(display_short)|uniprotkb:YNL287W(locus name)|uniprotkb:N0543(orf name)|uniprotkb:Gamma-coat protein(gene name synonym) psi-mi:copz_yeast(display_long)|uniprotkb:LPA7W(orf name)|uniprotkb:YP8132.03(orf name)|uniprotkb:RET3(gene name)|psi-mi:RET3(display_short)|uniprotkb:YPL010W(locus name)|uniprotkb:Zeta-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337977|imex:IM-14275-2186 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|ensemblfungi:YNL287W(gene)|ensemblfungi:YNL287W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|refseq:NP_014112.1|sgd:S000005231|dip:DIP-1611N|mint:P32074|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_015315.1|sgd:S000005931|dip:DIP-6809N|mint:P53600|ensemblfungi:YPL010W(gene)|ensemblfungi:YPL010W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR039652|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:99DC7D737D4EF761 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:uAs2hcx4DNS58qP1YDaUKgqZQm0559292 rogid:5xJ9ZinVUq4YB5e92ZexbjmB0rk559292 intact-crc:A384CE0E19BAB7CB|rigid:dMfjjWI5TIBHjvhEslZICwkIVZQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38084 uniprotkb:P53600 intact:EBI-3414|uniprotkb:D6VQ67|ensemblfungi:YBR068C intact:EBI-4905|uniprotkb:D6W402|ensemblfungi:YPL010W psi-mi:bap2_yeast(display_long)|uniprotkb:Branched-chain amino-acid permease 2(gene name synonym)|uniprotkb:BAP2(gene name)|psi-mi:BAP2(display_short)|uniprotkb:YBR068C(locus name)|uniprotkb:YBR0629(orf name) psi-mi:copz_yeast(display_long)|uniprotkb:LPA7W(orf name)|uniprotkb:YP8132.03(orf name)|uniprotkb:RET3(gene name)|psi-mi:RET3(display_short)|uniprotkb:YPL010W(locus name)|uniprotkb:Zeta-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337988|imex:IM-14275-2187 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000272|refseq:NP_009624.4|dip:DIP-4910N|mint:P38084|ensemblfungi:YBR068C(gene)|ensemblfungi:YBR068C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015192"(L-phenylalanine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098713"(leucine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) refseq:NP_015315.1|sgd:S000005931|dip:DIP-6809N|mint:P53600|ensemblfungi:YPL010W(gene)|ensemblfungi:YPL010W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR039652|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:B87FD6A7464E07F5 - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:7Fw7+M5mBikZBztHE2tSDpvBi/M559292 rogid:5xJ9ZinVUq4YB5e92ZexbjmB0rk559292 intact-crc:20ACE8A423633B51|rigid:cDhf5H7Gq53RbRr8keXj+6CaTDM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53600 uniprotkb:P41810 intact:EBI-4905|uniprotkb:D6W402|ensemblfungi:YPL010W intact:EBI-4869|uniprotkb:Q03779|uniprotkb:D6VSL9|ensemblfungi:YDR238C psi-mi:copz_yeast(display_long)|uniprotkb:LPA7W(orf name)|uniprotkb:YP8132.03(orf name)|uniprotkb:RET3(gene name)|psi-mi:RET3(display_short)|uniprotkb:YPL010W(locus name)|uniprotkb:Zeta-coat protein(gene name synonym) psi-mi:copb_yeast(display_long)|uniprotkb:SEC26(gene name)|psi-mi:SEC26(display_short)|uniprotkb:YDR238C(locus name)|uniprotkb:YD8419.05C(orf name)|uniprotkb:Beta-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6337999|imex:IM-14275-2188 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015315.1|sgd:S000005931|dip:DIP-6809N|mint:P53600|ensemblfungi:YPL010W(gene)|ensemblfungi:YPL010W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR039652|reactome:R-SCE-6807878|reactome:R-SCE-6811434 sgd:S000002646|refseq:NP_010524.3|dip:DIP-6467N|mint:P41810|ensemblfungi:YDR238C(gene)|ensemblfungi:YDR238C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|reactome:R-SCE-6798695|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - crc64:885420DB026BCFA3 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5xJ9ZinVUq4YB5e92ZexbjmB0rk559292 rogid:ZfLp1BUmvVuTiXn7/Zbf/3m6VtE559292 intact-crc:3B8B0F33D0F62586|rigid:GRP9mZIOHgeru7MeADaZ3Dl0laU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41811 uniprotkb:P53600 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W intact:EBI-4905|uniprotkb:D6W402|ensemblfungi:YPL010W psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:copz_yeast(display_long)|uniprotkb:LPA7W(orf name)|uniprotkb:YP8132.03(orf name)|uniprotkb:RET3(gene name)|psi-mi:RET3(display_short)|uniprotkb:YPL010W(locus name)|uniprotkb:Zeta-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338010|imex:IM-14275-2189 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_015315.1|sgd:S000005931|dip:DIP-6809N|mint:P53600|ensemblfungi:YPL010W(gene)|ensemblfungi:YPL010W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR039652|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:6A5E50BBEB02CB58 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 rogid:5xJ9ZinVUq4YB5e92ZexbjmB0rk559292 intact-crc:3A8B0F376D8FBDC4|rigid:KPfEOEL9DvcGbWNLq3GcqAPvsnQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43621 uniprotkb:P53600 intact:EBI-4876|uniprotkb:D6VTT4|ensemblfungi:YFR051C intact:EBI-4905|uniprotkb:D6W402|ensemblfungi:YPL010W psi-mi:copd_yeast(display_long)|uniprotkb:RET2(gene name)|psi-mi:RET2(display_short)|uniprotkb:YFR051C(locus name)|uniprotkb:Delta-coat protein(gene name synonym) psi-mi:copz_yeast(display_long)|uniprotkb:LPA7W(orf name)|uniprotkb:YP8132.03(orf name)|uniprotkb:RET3(gene name)|psi-mi:RET3(display_short)|uniprotkb:YPL010W(locus name)|uniprotkb:Zeta-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338021|imex:IM-14275-2190 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001947|refseq:NP_116709.3|dip:DIP-5255N|mint:P43621|ensemblfungi:YFR051C(gene)|ensemblfungi:YFR051C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|rcsb pdb:5FJW|rcsb pdb:5FJX|rcsb pdb:5FJZ|rcsb pdb:5FK0|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_015315.1|sgd:S000005931|dip:DIP-6809N|mint:P53600|ensemblfungi:YPL010W(gene)|ensemblfungi:YPL010W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR039652|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:AA730F046655EE5A - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:auvjuT8ffm1R4P3mRKEIWAsynW0559292 rogid:5xJ9ZinVUq4YB5e92ZexbjmB0rk559292 intact-crc:D1CD9FF560765ACF|rigid:bDkjSAARz7EqGZF/1d+qJOUNh8k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:P53600 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-4905|uniprotkb:D6W402|ensemblfungi:YPL010W psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:copz_yeast(display_long)|uniprotkb:LPA7W(orf name)|uniprotkb:YP8132.03(orf name)|uniprotkb:RET3(gene name)|psi-mi:RET3(display_short)|uniprotkb:YPL010W(locus name)|uniprotkb:Zeta-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338032|imex:IM-14275-2191 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 refseq:NP_015315.1|sgd:S000005931|dip:DIP-6809N|mint:P53600|ensemblfungi:YPL010W(gene)|ensemblfungi:YPL010W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR039652|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:5xJ9ZinVUq4YB5e92ZexbjmB0rk559292 intact-crc:B0388956E3C9ECCB|rigid:L9Koi+ozYc69seupV90ZaZfwBRU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35732 uniprotkb:P53691 intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C intact:EBI-5429|uniprotkb:Q6Q5K7|uniprotkb:D6VYL7|ensemblfungi:YLR216C psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:ppid_yeast(display_long)|uniprotkb:CPR6(gene name)|psi-mi:CPR6(display_short)|uniprotkb:YLR216C(locus name)|uniprotkb:L8167.24(orf name)|uniprotkb:Rotamase CPR6(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338043|imex:IM-14275-2192 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 refseq:NP_013317.1|sgd:S000004206|dip:DIP-1274N|mint:P53691|ensemblfungi:YLR216C(gene)|ensemblfungi:YLR216C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0042026"(protein refolding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR020892|interpro:IPR029000|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) crc64:05734E2D0B7389AC crc64:188666D94866DDDD figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 rogid:SUaJi3kS2xpEcuxgMcms2Bm3/Eo559292 intact-crc:456F1F46B6BB2580|rigid:Ew75WKeT/mFGFKrf91u2d54kADI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53691 uniprotkb:P53297 intact:EBI-5429|uniprotkb:Q6Q5K7|uniprotkb:D6VYL7|ensemblfungi:YLR216C intact:EBI-12961|uniprotkb:D6VUW2|ensemblfungi:YGR178C psi-mi:ppid_yeast(display_long)|uniprotkb:CPR6(gene name)|psi-mi:CPR6(display_short)|uniprotkb:YLR216C(locus name)|uniprotkb:L8167.24(orf name)|uniprotkb:Rotamase CPR6(gene name synonym) psi-mi:pbp1_yeast(display_long)|uniprotkb:PBP1(gene name)|psi-mi:PBP1(display_short)|uniprotkb:MRS16(gene name synonym)|uniprotkb:"Poly(A)-binding protein-binding protein"(gene name synonym)|uniprotkb:YGR178C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338054|imex:IM-14275-2193 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013317.1|sgd:S000004206|dip:DIP-1274N|mint:P53691|ensemblfungi:YLR216C(gene)|ensemblfungi:YLR216C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0042026"(protein refolding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR020892|interpro:IPR029000|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6798695 sgd:S000003410|ensemblfungi:YGR178C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0043621"(protein self-association)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1901524"(regulation of mitophagy)|go:"GO:1904262"(negative regulation of TORC1 signaling)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR025852|ensemblfungi:YGR178C(gene)|refseq:NP_011694.3|mint:P53297|dip:DIP-2464N psi-mi:"MI:0469"(intact) crc64:188666D94866DDDD crc64:92005F3A2346193E figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SUaJi3kS2xpEcuxgMcms2Bm3/Eo559292 rogid:LtXvbFHbcIwi3NJgeab11QUU2nI559292 intact-crc:DD7D9F7594A3B033|rigid:G7WW7Yh88MABqJ/9cuLhMpn56Zc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53691 uniprotkb:P53316 intact:EBI-5429|uniprotkb:Q6Q5K7|uniprotkb:D6VYL7|ensemblfungi:YLR216C intact:EBI-23586|uniprotkb:D6VV30|ensemblfungi:YGR250C psi-mi:ppid_yeast(display_long)|uniprotkb:CPR6(gene name)|psi-mi:CPR6(display_short)|uniprotkb:YLR216C(locus name)|uniprotkb:L8167.24(orf name)|uniprotkb:Rotamase CPR6(gene name synonym) psi-mi:yg5b_yeast(display_long)|uniprotkb:YGR250C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338065|imex:IM-14275-2194 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013317.1|sgd:S000004206|dip:DIP-1274N|mint:P53691|ensemblfungi:YLR216C(gene)|ensemblfungi:YLR216C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0042026"(protein refolding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR020892|interpro:IPR029000|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6798695 refseq:NP_011766.3|sgd:S000003482|dip:DIP-5559N|mint:P53316|ensemblfungi:YGR250C(gene)|ensemblfungi:YGR250C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979 psi-mi:"MI:0469"(intact) crc64:188666D94866DDDD crc64:C2CA1CBF5F6D395B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SUaJi3kS2xpEcuxgMcms2Bm3/Eo559292 rogid:PMluELxwVWyCMyMnmOBp0HyI604559292 intact-crc:099AFE710C3559CA|rigid:5//SSeTn9M5q3n6+V9Lcx5dDTIM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53730 uniprotkb:P16474 intact:EBI-28496|uniprotkb:D6W1K4|ensemblfungi:YNR030W intact:EBI-7876|ensemblfungi:YJL034W|uniprotkb:D6VWE9 psi-mi:alg12_yeast(display_long)|uniprotkb:ALG12(gene name)|psi-mi:ALG12(display_short)|uniprotkb:ECM39(gene name synonym)|uniprotkb:YNR030W(locus name)|uniprotkb:N3265(orf name)|uniprotkb:Mannosyltransferase ALG12(gene name synonym)|uniprotkb:Extracellular mutant protein 39(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase"(gene name synonym)|uniprotkb:Asparagine-linked glycosylation protein 12(gene name synonym) psi-mi:bip_yeast(display_long)|uniprotkb:KAR2(gene name)|psi-mi:KAR2(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:SSD1(gene name synonym)|uniprotkb:YJL034W(locus name)|uniprotkb:J1248(orf name)|uniprotkb:Immunoglobulin heavy chain-binding protein homolog(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein homolog(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338076|imex:IM-14275-2195 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014427.1|sgd:S000005313|dip:DIP-4259N|mint:P53730|ensemblfungi:YNR030W(gene)|ensemblfungi:YNR030W_mRNA(transcript)|go:"GO:0000009"(alpha-1,6-mannosyltransferase activity)|go:"GO:0000030"(mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052917"("dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase")|interpro:IPR005599(Alg9-like mannosyltransferase)|interpro:IPR039485|reactome:R-SCE-446193 sgd:S000003571|ensemblfungi:YJL034W(gene)|ensemblfungi:YJL034W_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|refseq:NP_012500.3|mint:P16474|dip:DIP-2392N|rcsb pdb:3QFP|rcsb pdb:3QFU|rcsb pdb:3QML|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0034099"(luminal surveillance complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070880"(fungal-type cell wall beta-glucan biosynthetic process)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|rcsb pdb:3H0X psi-mi:"MI:0469"(intact) - crc64:A107BD03DF3F30D3 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3OdDOcUZm9NImnU+imd8xJwvb/Q559292 rogid:+zA2eFylZ+4FgQ5zac8xx/GRV7g559292 intact-crc:DC089EF0BAE069C7|rigid:aerceHJbxJOm3Z9TbUbKUsbH7LM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33204 uniprotkb:P53731 intact:EBI-2757|uniprotkb:D6VXS3|ensemblfungi:YKL013C intact:EBI-2770|uniprotkb:D6W1L1|ensemblfungi:YNR035C psi-mi:arpc4_yeast(display_long)|uniprotkb:ARC19(gene name)|psi-mi:ARC19(display_short)|uniprotkb:YKL013C(locus name)|uniprotkb:YKL166(orf name)|uniprotkb:Arp2/3 complex 20 kDa(gene name synonym) psi-mi:arpc2_yeast(display_long)|uniprotkb:ARC35(gene name)|psi-mi:ARC35(display_short)|uniprotkb:YNR035C(locus name)|uniprotkb:N3296(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338087|imex:IM-14275-2196 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012912.1|sgd:S000001496|dip:DIP-1819N|mint:P33204|ensemblfungi:YKL013C(gene)|ensemblfungi:YKL013C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 refseq:NP_014433.1|sgd:S000005318|dip:DIP-2304N|mint:P53731|ensemblfungi:YNR035C(gene)|ensemblfungi:YNR035C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072697"(protein localization to cell cortex)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:B80CBD6642E39C1C crc64:9AF71A93688729F6 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wscMsqBK/3Rsah+2vbE3REyYhhg559292 rogid:URdgP2srz1O44fNGQh18L7bzC+c559292 intact-crc:0C8B7CED423DC20E|rigid:hQi8BsCy5PnGdR/UDoN+K4jrLuE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53731 uniprotkb:P37370 intact:EBI-2770|uniprotkb:D6W1L1|ensemblfungi:YNR035C intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C psi-mi:arpc2_yeast(display_long)|uniprotkb:ARC35(gene name)|psi-mi:ARC35(display_short)|uniprotkb:YNR035C(locus name)|uniprotkb:N3296(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym) psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338098|imex:IM-14275-2197 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014433.1|sgd:S000005318|dip:DIP-2304N|mint:P53731|ensemblfungi:YNR035C(gene)|ensemblfungi:YNR035C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072697"(protein localization to cell cortex)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370 psi-mi:"MI:0469"(intact) crc64:9AF71A93688729F6 crc64:24C7522D5B1CA1C8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:URdgP2srz1O44fNGQh18L7bzC+c559292 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 intact-crc:FDB8A07BA8ED6043|rigid:NpzTg5Yuqv9lpAMW2zUheETtvM8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38328 uniprotkb:P53731 intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C intact:EBI-2770|uniprotkb:D6W1L1|ensemblfungi:YNR035C psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:arpc2_yeast(display_long)|uniprotkb:ARC35(gene name)|psi-mi:ARC35(display_short)|uniprotkb:YNR035C(locus name)|uniprotkb:N3296(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338109|imex:IM-14275-2198 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 refseq:NP_014433.1|sgd:S000005318|dip:DIP-2304N|mint:P53731|ensemblfungi:YNR035C(gene)|ensemblfungi:YNR035C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072697"(protein localization to cell cortex)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:D75C6BB8EC35EEDF crc64:9AF71A93688729F6 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 rogid:URdgP2srz1O44fNGQh18L7bzC+c559292 intact-crc:7952577155690773|rigid:fIXKDJMWJgDFx5+MW3DzExMy5Ns false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53731 uniprotkb:Q05933 intact:EBI-2770|uniprotkb:D6W1L1|ensemblfungi:YNR035C intact:EBI-2764|uniprotkb:D6VZ07|ensemblfungi:YLR370C psi-mi:arpc2_yeast(display_long)|uniprotkb:ARC35(gene name)|psi-mi:ARC35(display_short)|uniprotkb:YNR035C(locus name)|uniprotkb:N3296(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym) psi-mi:arpc3_yeast(display_long)|uniprotkb:ARC18(gene name)|psi-mi:ARC18(display_short)|uniprotkb:YLR370C(locus name)|uniprotkb:L8039.15(orf name)|uniprotkb:Arp2/3 complex 21 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338120|imex:IM-14275-2199 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014433.1|sgd:S000005318|dip:DIP-2304N|mint:P53731|ensemblfungi:YNR035C(gene)|ensemblfungi:YNR035C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072697"(protein localization to cell cortex)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 sgd:S000004362|refseq:NP_013474.3|dip:DIP-2218N|mint:Q05933|ensemblfungi:YLR370C(gene)|ensemblfungi:YLR370C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR007204(ARP2/3 complex, 21 kDa p21-Arc subunit)|interpro:IPR036753|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:9AF71A93688729F6 crc64:456EABC2B9CC4860 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:URdgP2srz1O44fNGQh18L7bzC+c559292 rogid:Fj4cwULcw1TK5uS1lJczcNc5gns559292 intact-crc:3F6B05D8912BC8BD|rigid:AGypmGsYag8VkraTgYBolvtAnKQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53731 uniprotkb:Q12446 intact:EBI-2770|uniprotkb:D6W1L1|ensemblfungi:YNR035C intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W psi-mi:arpc2_yeast(display_long)|uniprotkb:ARC35(gene name)|psi-mi:ARC35(display_short)|uniprotkb:YNR035C(locus name)|uniprotkb:N3296(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym) psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338131|imex:IM-14275-2200 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014433.1|sgd:S000005318|dip:DIP-2304N|mint:P53731|ensemblfungi:YNR035C(gene)|ensemblfungi:YNR035C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072697"(protein localization to cell cortex)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446 psi-mi:"MI:0469"(intact) crc64:9AF71A93688729F6 crc64:4488355563AA2645 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:URdgP2srz1O44fNGQh18L7bzC+c559292 rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292 intact-crc:CFE5D80DDFF04679|rigid:6zc5ueimvibtevHSMoNOUeBIkdU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32495 uniprotkb:P53734 intact:EBI-12014|ensemblfungi:YDL208W|uniprotkb:D6VRE6 intact:EBI-5625|uniprotkb:D6W1L4|ensemblfungi:YNR038W psi-mi:nhp2_yeast(display_long)|uniprotkb:NHP2(gene name)|psi-mi:NHP2(display_short)|uniprotkb:YDL208W(locus name)|uniprotkb:D1045(orf name)|uniprotkb:H/ACA snoRNP protein NHP2(gene name synonym)|uniprotkb:High mobility group-like nuclear protein 2(gene name synonym) psi-mi:dbp6_yeast(display_long)|uniprotkb:DBP6(gene name)|psi-mi:DBP6(display_short)|uniprotkb:YNR038W(locus name)|uniprotkb:N3302(orf name)|uniprotkb:DEAD box protein 6(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338142|imex:IM-14275-2201 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDL208W(gene)|ensemblfungi:YDL208W_mRNA(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000493"(box H/ACA snoRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|rcsb pdb:2LBW|rcsb pdb:2LBX|refseq:NP_010073.2|sgd:S000002367|mint:P32495|dip:DIP-5134N refseq:NP_014436.1|sgd:S000005321|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR027417|mint:P53734|ensemblfungi:YNR038W(gene)|ensemblfungi:YNR038W_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0140603"(obsolete ATP hydrolysis activity) psi-mi:"MI:0469"(intact) crc64:008188132B494E5D - figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p5AQTuMF3Vvdu6HWSTYjdjjE1Vs559292 rogid:uhaxMF80Y3qhNadqbZVjkYbaxlA559292 intact-crc:7326E1566C2C43B9|rigid:oXS2N0cfxjSIOWY9au32YfuSdQs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53741 uniprotkb:P06634 intact:EBI-28528|uniprotkb:D6W1M6|ensemblfungi:YNR051C intact:EBI-5744|uniprotkb:D6W2R0|ensemblfungi:YOR204W psi-mi:bre5_yeast(display_long)|uniprotkb:BRE5(gene name)|psi-mi:BRE5(display_short)|uniprotkb:YNR051C(locus name)|uniprotkb:N3465(orf name)|uniprotkb:Brefeldin-A sensitivity protein 5(gene name synonym) psi-mi:ded1_yeast(display_long)|uniprotkb:DED1(gene name)|psi-mi:DED1(display_short)|uniprotkb:SPP81(gene name synonym)|uniprotkb:YOR204W(locus name)|uniprotkb:DEAD box protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338153|imex:IM-14275-2202 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014449.1|sgd:S000005334|dip:DIP-4254N|mint:P53741|ensemblfungi:YNR051C(gene)|ensemblfungi:YNR051C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0034517"(ribophagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1990861"(Ubp3-Bre5 deubiquitination complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000156"(regulation of retrograde vesicle-mediated transport, Golgi to ER)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710|interpro:IPR039539|rcsb pdb:1ZX2|rcsb pdb:2QIY sgd:S000005730|refseq:NP_014847.3|dip:DIP-5820N|mint:P06634|ensemblfungi:YOR204W(gene)|ensemblfungi:YOR204W_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:B6722D94C03BFA4B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:DIP3qqPEixSKoo2gi7O9Zsrj7wk559292 rogid:FkldumX6m5gBuuaG09aTJ0kuMZM559292 intact-crc:7AC886081E11669E|rigid:nsIfhWhpnAVYL51FAKyngTWLvqw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25567 uniprotkb:P53741 intact:EBI-18084|uniprotkb:D6VQX8|ensemblfungi:YCL037C intact:EBI-28528|uniprotkb:D6W1M6|ensemblfungi:YNR051C psi-mi:sro9_yeast(display_long)|uniprotkb:SRO9(gene name)|psi-mi:SRO9(display_short)|uniprotkb:YCL037C(locus name)|uniprotkb:YCL37C(orf name)|uniprotkb:Suppressor of RHO3 protein 9(gene name synonym) psi-mi:bre5_yeast(display_long)|uniprotkb:BRE5(gene name)|psi-mi:BRE5(display_short)|uniprotkb:YNR051C(locus name)|uniprotkb:N3465(orf name)|uniprotkb:Brefeldin-A sensitivity protein 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338164|imex:IM-14275-2203 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009893.2|sgd:S000000542|ensemblfungi:YCL037C(gene)|ensemblfungi:YCL037C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|dip:DIP-6638N|mint:P25567 refseq:NP_014449.1|sgd:S000005334|dip:DIP-4254N|mint:P53741|ensemblfungi:YNR051C(gene)|ensemblfungi:YNR051C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0034517"(ribophagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1990861"(Ubp3-Bre5 deubiquitination complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000156"(regulation of retrograde vesicle-mediated transport, Golgi to ER)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710|interpro:IPR039539|rcsb pdb:1ZX2|rcsb pdb:2QIY psi-mi:"MI:0469"(intact) crc64:B1B720D40C7B9914 - figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CouwiBsK7S3Tm6CoBsu3LdWfelg559292 rogid:DIP3qqPEixSKoo2gi7O9Zsrj7wk559292 intact-crc:6168DA180DDE9BE5|rigid:PfFda+VqJs/PuUPolWYYC3gcj64 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53235 uniprotkb:P53741 intact:EBI-23172|uniprotkb:D6VUI9|uniprotkb:Q45U32|ensemblfungi:YGR054W intact:EBI-28528|uniprotkb:D6W1M6|ensemblfungi:YNR051C psi-mi:eif2a_yeast(display_long)|uniprotkb:YGR054W(locus name) psi-mi:bre5_yeast(display_long)|uniprotkb:BRE5(gene name)|psi-mi:BRE5(display_short)|uniprotkb:YNR051C(locus name)|uniprotkb:N3465(orf name)|uniprotkb:Brefeldin-A sensitivity protein 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338175|imex:IM-14275-2204 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003286|refseq:NP_011568.3|dip:DIP-5518N|mint:P53235|ensemblfungi:YGR054W(gene)|ensemblfungi:YGR054W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like) refseq:NP_014449.1|sgd:S000005334|dip:DIP-4254N|mint:P53741|ensemblfungi:YNR051C(gene)|ensemblfungi:YNR051C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0034517"(ribophagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1990861"(Ubp3-Bre5 deubiquitination complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000156"(regulation of retrograde vesicle-mediated transport, Golgi to ER)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710|interpro:IPR039539|rcsb pdb:1ZX2|rcsb pdb:2QIY psi-mi:"MI:0469"(intact) crc64:F3C2E78504D83418 - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:x8zDCH5W5GusC7qYd0mDATXhGVI559292 rogid:DIP3qqPEixSKoo2gi7O9Zsrj7wk559292 intact-crc:8B37D6DB467A1D64|rigid:4J/pU4H48o7T5SD9M/sWydH+/IE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53741 uniprotkb:P53741 intact:EBI-28528|uniprotkb:D6W1M6|ensemblfungi:YNR051C intact:EBI-28528|uniprotkb:D6W1M6|ensemblfungi:YNR051C psi-mi:bre5_yeast(display_long)|uniprotkb:BRE5(gene name)|psi-mi:BRE5(display_short)|uniprotkb:YNR051C(locus name)|uniprotkb:N3465(orf name)|uniprotkb:Brefeldin-A sensitivity protein 5(gene name synonym) psi-mi:bre5_yeast(display_long)|uniprotkb:BRE5(gene name)|psi-mi:BRE5(display_short)|uniprotkb:YNR051C(locus name)|uniprotkb:N3465(orf name)|uniprotkb:Brefeldin-A sensitivity protein 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338186|imex:IM-14275-2205 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014449.1|sgd:S000005334|dip:DIP-4254N|mint:P53741|ensemblfungi:YNR051C(gene)|ensemblfungi:YNR051C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0034517"(ribophagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1990861"(Ubp3-Bre5 deubiquitination complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000156"(regulation of retrograde vesicle-mediated transport, Golgi to ER)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710|interpro:IPR039539|rcsb pdb:1ZX2|rcsb pdb:2QIY refseq:NP_014449.1|sgd:S000005334|dip:DIP-4254N|mint:P53741|ensemblfungi:YNR051C(gene)|ensemblfungi:YNR051C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0034517"(ribophagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1990861"(Ubp3-Bre5 deubiquitination complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000156"(regulation of retrograde vesicle-mediated transport, Golgi to ER)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710|interpro:IPR039539|rcsb pdb:1ZX2|rcsb pdb:2QIY psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:DIP3qqPEixSKoo2gi7O9Zsrj7wk559292 rogid:DIP3qqPEixSKoo2gi7O9Zsrj7wk559292 intact-crc:278E4A91B2D56CB4|rigid:xbxcnJIBLPnAFnnfTZA6VKA1MIU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53849 uniprotkb:P53741 intact:EBI-29244|uniprotkb:D6W0T8|ensemblfungi:YNL255C intact:EBI-28528|uniprotkb:D6W1M6|ensemblfungi:YNR051C psi-mi:gis2_yeast(display_long)|uniprotkb:GIS2(gene name)|psi-mi:GIS2(display_short)|uniprotkb:N0852(orf name)|uniprotkb:YNL255C(locus name) psi-mi:bre5_yeast(display_long)|uniprotkb:BRE5(gene name)|psi-mi:BRE5(display_short)|uniprotkb:YNR051C(locus name)|uniprotkb:N3465(orf name)|uniprotkb:Brefeldin-A sensitivity protein 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338197|imex:IM-14275-2206 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014144.1|sgd:S000005199|dip:DIP-2669N|mint:P53849|ensemblfungi:YNL255C(gene)|ensemblfungi:YNL255C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045182"(translation regulator activity)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875 refseq:NP_014449.1|sgd:S000005334|dip:DIP-4254N|mint:P53741|ensemblfungi:YNR051C(gene)|ensemblfungi:YNR051C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0034517"(ribophagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1990861"(Ubp3-Bre5 deubiquitination complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000156"(regulation of retrograde vesicle-mediated transport, Golgi to ER)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710|interpro:IPR039539|rcsb pdb:1ZX2|rcsb pdb:2QIY psi-mi:"MI:0469"(intact) crc64:E72696428F85CA3F - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kftHFJVi7QRZASmr4hLdALvleR4559292 rogid:DIP3qqPEixSKoo2gi7O9Zsrj7wk559292 intact-crc:9C7A7047F5B4487C|rigid:R2bZbUYh+/bu6SchWTK73vfbAj0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53742 uniprotkb:Q12522 intact:EBI-28532|uniprotkb:D6W1M8|ensemblfungi:YNR053C intact:EBI-9046|ensemblfungi:YPR016C|uniprotkb:D6W426 psi-mi:nog2_yeast(display_long)|uniprotkb:NOG2(gene name)|psi-mi:NOG2(display_short)|uniprotkb:N3484(orf name)|uniprotkb:YNR053C(locus name) psi-mi:if6_yeast(display_long)|uniprotkb:TIF6(gene name)|psi-mi:TIF6(display_short)|uniprotkb:CDC95(gene name synonym)|uniprotkb:YPR016C(locus name)|uniprotkb:LPZ15C(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338208|imex:IM-14275-2207 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014451.1|sgd:S000005336|dip:DIP-976N|mint:P53742|ensemblfungi:YNR053C(gene)|ensemblfungi:YNR053C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:2000200"(regulation of ribosomal subunit export from nucleus)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012971(NGP1, N-terminal)|interpro:IPR023179|interpro:IPR024929|interpro:IPR027417|interpro:IPR030378|rcsb pdb:3JCT|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:6YLG|rcsb pdb:6YLH|rcsb pdb:7BT6|rcsb pdb:7BTB rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:6N8K|rcsb pdb:6N8L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R86|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:6EM1|rcsb pdb:6RZZ|rcsb pdb:6S05|rcsb pdb:6YLG|ensemblfungi:YPR016C(gene)|ensemblfungi:YPR016C_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR002769(Translation initiation factor IF6)|rcsb pdb:1G62|rcsb pdb:2X7N|rcsb pdb:3J2I|rcsb pdb:3JCT|rcsb pdb:4V7F|rcsb pdb:5FL8|rcsb pdb:5H4P|rcsb pdb:5JCS|rcsb pdb:5T62|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:7BTB|rcsb pdb:6YLH|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BT6|rcsb pdb:6ELZ|refseq:NP_015341.1|sgd:S000006220|mint:Q12522|dip:DIP-5395N psi-mi:"MI:0469"(intact) crc64:D7F670973B85CCEB crc64:1BCE041C61DFD2A8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oWCL90Qd+LFA4SHdZgdz0gtSD0I559292 rogid:FI24/9LOZsCJEfbb7pjCQ+C8i/U559292 intact-crc:36B63D1B4F63E714|rigid:beDHrlz12lxvVrPchtyv7sha9YE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53819 uniprotkb:P32445 intact:EBI-2103894|uniprotkb:O94144|uniprotkb:D6W0L0|ensemblfungi:YNL339C intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A psi-mi:yrf16_yeast(display_long)|uniprotkb:YRF1-6(gene name)|psi-mi:YRF1-6(display_short)|uniprotkb:N0152(orf name)|uniprotkb:YNL339C(locus name) psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338219|imex:IM-14275-2208 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014060.1|sgd:S000005283|dip:DIP-7312N|mint:P53819|ensemblfungi:YNL339C(gene)|ensemblfungi:YNL339C_mRNA(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021646|interpro:IPR027417|interpro:IPR037240 refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 psi-mi:"MI:0469"(intact) - crc64:9F913C2FC9EF6E82 figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cSTc0GokFcmNo10zz1sEtqLkcmM559292 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 intact-crc:62DD88E8E730FBF1|rigid:Imlfae5trfYPyj1uPMzsmrSCG0o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38235 uniprotkb:P53819 intact:EBI-21449|uniprotkb:D6VQ52|uniprotkb:Q6Q5P3|ensemblfungi:YBR053C intact:EBI-2103894|uniprotkb:O94144|uniprotkb:D6W0L0|ensemblfungi:YNL339C psi-mi:ybq3_yeast(display_long)|uniprotkb:YBR0506(orf name)|uniprotkb:YBR053C(locus name) psi-mi:yrf16_yeast(display_long)|uniprotkb:YRF1-6(gene name)|psi-mi:YRF1-6(display_short)|uniprotkb:N0152(orf name)|uniprotkb:YNL339C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338230|imex:IM-14275-2209 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009609.1|sgd:S000000257|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013658(SMP-30/Gluconolaconase/LRE-like region)|mint:P38235|ensemblfungi:YBR053C(gene)|ensemblfungi:YBR053C_mRNA(transcript)|go:"GO:0004341"(gluconolactonase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0019853"(L-ascorbic acid biosynthetic process) refseq:NP_014060.1|sgd:S000005283|dip:DIP-7312N|mint:P53819|ensemblfungi:YNL339C(gene)|ensemblfungi:YNL339C_mRNA(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021646|interpro:IPR027417|interpro:IPR037240 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TStDtjZsqdqErK7CCygavX4ly+U559292 rogid:cSTc0GokFcmNo10zz1sEtqLkcmM559292 intact-crc:8C941A92F81934BC|rigid:V561p42T2zqYBwEJX0Vb2rk32og false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:P53822 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-4959|ensemblfungi:YNL336W|uniprotkb:D6W0L1 psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:cos1_yeast(display_long)|uniprotkb:COS1(gene name)|psi-mi:COS1(display_short)|uniprotkb:N0275(orf name)|uniprotkb:YNL336W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338241|imex:IM-14275-2210 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N ensemblfungi:YNL336W(gene)|ensemblfungi:YNL336W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|interpro:IPR001142(Yeast membrane protein DUP)|sgd:S000005280|refseq:NP_014063.1|dip:DIP-7523N|mint:P53822 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:NJD0bZ207ojfx67Ozcefe4KQCYY559292 intact-crc:8191F31079483FBF|rigid:kxwsvNpiaPcXxgKwPTodsw80ZYg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53829 uniprotkb:P06102 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-12165|uniprotkb:D6VVP4|uniprotkb:Q6B233|ensemblfungi:YIL038C psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:not3_yeast(display_long)|uniprotkb:NOT3(gene name)|psi-mi:NOT3(display_short)|uniprotkb:YIL038C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338252|imex:IM-14275-2211 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR038635|interpro:IPR040168|ensemblfungi:YIL038C(gene)|ensemblfungi:YIL038C_mRNA(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|refseq:NP_012226.3|sgd:S000001300|dip:DIP-2256N|mint:P06102 psi-mi:"MI:0469"(intact) crc64:F3DBABE6AD3C7F3C crc64:69B76694FCC6846F figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:EfakZPDNU3FZeI5+rnu7YV1UsCg559292 intact-crc:59D571CF074192DB|rigid:Dv3rjV+1ksgB/H3FME/7jkfwCJ8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25655 uniprotkb:P53829 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338263|imex:IM-14275-2212 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 psi-mi:"MI:0469"(intact) crc64:5B2AE15BCF95E009 crc64:F3DBABE6AD3C7F3C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 intact-crc:1DC3E69DE95AFB4E|rigid:isaYayYhAW9IbzmUvfvFVgG+ub0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53829 uniprotkb:P34909 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338274|imex:IM-14275-2213 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 psi-mi:"MI:0469"(intact) crc64:F3DBABE6AD3C7F3C crc64:8847084BD9BF48B7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 intact-crc:CE92D82480021AB6|rigid:8cVnmhmeEe1Ac03UONcz0T2ajoA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53829 uniprotkb:P35732 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338285|imex:IM-14275-2214 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 psi-mi:"MI:0469"(intact) crc64:F3DBABE6AD3C7F3C crc64:05734E2D0B7389AC figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 intact-crc:F8DAFA0DA1BD9AAC|rigid:7yCl8UNtCDbF4vKoFSX8DSgrFhM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53829 uniprotkb:P39008 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338296|imex:IM-14275-2215 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N psi-mi:"MI:0469"(intact) crc64:F3DBABE6AD3C7F3C crc64:F3CAF97106A65933 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 intact-crc:C3F498CD3D5AE7E2|rigid:9Aa39iMdYZHr97bGe+lv5BcKASg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53829 uniprotkb:P40070 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338307|imex:IM-14275-2216 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:F3DBABE6AD3C7F3C crc64:69CAC1F01D5BFA98 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 intact-crc:ABEBF40DEEA46872|rigid:/AnLS+CobssE3R1Snp1lXSOuIJw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53829 uniprotkb:P53829 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338318|imex:IM-14275-2217 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 psi-mi:"MI:0469"(intact) crc64:F3DBABE6AD3C7F3C crc64:F3DBABE6AD3C7F3C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 intact-crc:DF0AC958D1117F58|rigid:EPcUdJhdWhAGNwCYI0My6jZi1gU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53829 uniprotkb:P53935 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-28788|uniprotkb:Q45TZ3|uniprotkb:D6W189|ensemblfungi:YNL091W psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:nst1_yeast(display_long)|uniprotkb:YNL091W(locus name)|uniprotkb:N2231(orf name)|uniprotkb:NST1(gene name)|psi-mi:NST1(display_short)|uniprotkb:Negatively-affecting salt tolerance protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338329|imex:IM-14275-2218 author score:89.41 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 refseq:NP_014308.1|sgd:S000005035|dip:DIP-872N|mint:P53935|ensemblfungi:YNL091W(gene)|ensemblfungi:YNL091W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009651"(response to salt stress)|interpro:IPR025279 psi-mi:"MI:0469"(intact) crc64:F3DBABE6AD3C7F3C - figure legend:tables S3 and S4|author-confidence:89.41|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:WOSVMqWhtYPlZyt+vfdkpJAHHBg559292 intact-crc:9229EC8344609506|rigid:BFXOfDYFe1caFQAP2Teigpznn/s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53829 uniprotkb:Q12514 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-12184|uniprotkb:D6W476|ensemblfungi:YPR072W psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:not5_yeast(display_long)|uniprotkb:NOT5(gene name)|psi-mi:NOT5(display_short)|uniprotkb:YP9499.27(orf name)|uniprotkb:YPR072W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338340|imex:IM-14275-2219 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 ensemblfungi:YPR072W(gene)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|rcsb pdb:6TB3|ensemblfungi:YPR072W_mRNA(transcript)|refseq:NP_015397.1|sgd:S000006276|dip:DIP-2257N|mint:Q12514 psi-mi:"MI:0469"(intact) crc64:F3DBABE6AD3C7F3C crc64:073137119B3E92BC figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:+XON8Ps4xCFhw058U9d2voUy2dc559292 intact-crc:53769FCAC6E7982B|rigid:O6qlgISdc32rXVT3kKeBYHIJwlE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53832 uniprotkb:P19807 intact:EBI-2055941|uniprotkb:D6W0R1|ensemblfungi:YNL283C intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:wsc2_yeast(display_long)|uniprotkb:YNL283C(locus name)|uniprotkb:N0583(orf name)|uniprotkb:WSC2(gene name)|psi-mi:WSC2(display_short) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338351|imex:IM-14275-2220 author score:99.26 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014116.1|sgd:S000005227|interpro:IPR002889(Carbohydrate-binding WSC)|mint:P53832|ensemblfungi:YNL283C(gene)|ensemblfungi:YNL283C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.26|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5wadvTv6SxcIAb60yfnuGMfa8pY559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:B8AD33194144E3FD|rigid:dxvX6ff0awlmmKM8g4oi5ODEeSc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53832 uniprotkb:P36027 intact:EBI-2055941|uniprotkb:D6W0R1|ensemblfungi:YNL283C intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:wsc2_yeast(display_long)|uniprotkb:YNL283C(locus name)|uniprotkb:N0583(orf name)|uniprotkb:WSC2(gene name)|psi-mi:WSC2(display_short) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338362|imex:IM-14275-2221 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014116.1|sgd:S000005227|interpro:IPR002889(Carbohydrate-binding WSC)|mint:P53832|ensemblfungi:YNL283C(gene)|ensemblfungi:YNL283C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5wadvTv6SxcIAb60yfnuGMfa8pY559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:706592888A1BC1D1|rigid:0ycxvHn5tf7oy14lM97FQ0llFkg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53832 uniprotkb:P38234 intact:EBI-2055941|uniprotkb:D6W0R1|ensemblfungi:YNL283C intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C psi-mi:wsc2_yeast(display_long)|uniprotkb:YNL283C(locus name)|uniprotkb:N0583(orf name)|uniprotkb:WSC2(gene name)|psi-mi:WSC2(display_short) psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338373|imex:IM-14275-2222 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014116.1|sgd:S000005227|interpro:IPR002889(Carbohydrate-binding WSC)|mint:P53832|ensemblfungi:YNL283C(gene)|ensemblfungi:YNL283C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip) refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5wadvTv6SxcIAb60yfnuGMfa8pY559292 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 intact-crc:922B48CB49255418|rigid:OMoL1dyU5wuT5wXHbp5bkXXOl10 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53832 uniprotkb:P39719 intact:EBI-2055941|uniprotkb:D6W0R1|ensemblfungi:YNL283C intact:EBI-20703|uniprotkb:Q05165|uniprotkb:D6VPG5|ensemblfungi:YAL053W psi-mi:wsc2_yeast(display_long)|uniprotkb:YNL283C(locus name)|uniprotkb:N0583(orf name)|uniprotkb:WSC2(gene name)|psi-mi:WSC2(display_short) psi-mi:flc2_yeast(display_long)|uniprotkb:YAL053W(locus name)|uniprotkb:FLC2(gene name)|psi-mi:FLC2(display_short)|uniprotkb:FAD transporter 2(gene name synonym)|uniprotkb:TRP-like ion channel FLC2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338384|imex:IM-14275-2223 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014116.1|sgd:S000005227|interpro:IPR002889(Carbohydrate-binding WSC)|mint:P53832|ensemblfungi:YNL283C(gene)|ensemblfungi:YNL283C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip) refseq:NP_009348.2|sgd:S000000049|ensemblfungi:YAL053W(gene)|ensemblfungi:YAL053W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241|go:"GO:0055085"(transmembrane transport)|dip:DIP-6708N|mint:P39719 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5wadvTv6SxcIAb60yfnuGMfa8pY559292 rogid:NOmMW54DNa0o7vM945DlZgVUy44559292 intact-crc:99454299E31AD050|rigid:P0gnS+QbF3jzEFzZaTXnPrghixc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53832 uniprotkb:P50276 intact:EBI-2055941|uniprotkb:D6W0R1|ensemblfungi:YNL283C intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:wsc2_yeast(display_long)|uniprotkb:YNL283C(locus name)|uniprotkb:N0583(orf name)|uniprotkb:WSC2(gene name)|psi-mi:WSC2(display_short) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338395|imex:IM-14275-2224 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014116.1|sgd:S000005227|interpro:IPR002889(Carbohydrate-binding WSC)|mint:P53832|ensemblfungi:YNL283C(gene)|ensemblfungi:YNL283C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5wadvTv6SxcIAb60yfnuGMfa8pY559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:F3D435A96723A70D|rigid:jil0n1FWeFMb42cc91cwdMVcn8Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53139 uniprotkb:P53832 intact:EBI-23908|uniprotkb:D6VU38|ensemblfungi:YGL108C intact:EBI-2055941|uniprotkb:D6W0R1|ensemblfungi:YNL283C psi-mi:ygk8_yeast(display_long)|uniprotkb:G3070(orf name)|uniprotkb:YGL108C(locus name) psi-mi:wsc2_yeast(display_long)|uniprotkb:YNL283C(locus name)|uniprotkb:N0583(orf name)|uniprotkb:WSC2(gene name)|psi-mi:WSC2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338406|imex:IM-14275-2225 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003076|refseq:NP_011407.3|mint:P53139|ensemblfungi:YGL108C(gene)|ensemblfungi:YGL108C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane) refseq:NP_014116.1|sgd:S000005227|interpro:IPR002889(Carbohydrate-binding WSC)|mint:P53832|ensemblfungi:YNL283C(gene)|ensemblfungi:YNL283C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6rg2zcMN57peeKKy/RolIDcNaLc559292 rogid:5wadvTv6SxcIAb60yfnuGMfa8pY559292 intact-crc:C4646040A45B80FF|rigid:Ab1CKG84IgtXuoX6IxMzQA+oXBM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53832 uniprotkb:P53832 intact:EBI-2055941|uniprotkb:D6W0R1|ensemblfungi:YNL283C intact:EBI-2055941|uniprotkb:D6W0R1|ensemblfungi:YNL283C psi-mi:wsc2_yeast(display_long)|uniprotkb:YNL283C(locus name)|uniprotkb:N0583(orf name)|uniprotkb:WSC2(gene name)|psi-mi:WSC2(display_short) psi-mi:wsc2_yeast(display_long)|uniprotkb:YNL283C(locus name)|uniprotkb:N0583(orf name)|uniprotkb:WSC2(gene name)|psi-mi:WSC2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338417|imex:IM-14275-2226 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014116.1|sgd:S000005227|interpro:IPR002889(Carbohydrate-binding WSC)|mint:P53832|ensemblfungi:YNL283C(gene)|ensemblfungi:YNL283C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip) refseq:NP_014116.1|sgd:S000005227|interpro:IPR002889(Carbohydrate-binding WSC)|mint:P53832|ensemblfungi:YNL283C(gene)|ensemblfungi:YNL283C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5wadvTv6SxcIAb60yfnuGMfa8pY559292 rogid:5wadvTv6SxcIAb60yfnuGMfa8pY559292 intact-crc:373450309FC18812|rigid:g1RwvcoAhsoYXW6YimakgRXa/pc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53832 uniprotkb:Q02785 intact:EBI-2055941|uniprotkb:D6W0R1|ensemblfungi:YNL283C intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:wsc2_yeast(display_long)|uniprotkb:YNL283C(locus name)|uniprotkb:N0583(orf name)|uniprotkb:WSC2(gene name)|psi-mi:WSC2(display_short) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338428|imex:IM-14275-2227 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014116.1|sgd:S000005227|interpro:IPR002889(Carbohydrate-binding WSC)|mint:P53832|ensemblfungi:YNL283C(gene)|ensemblfungi:YNL283C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip) refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5wadvTv6SxcIAb60yfnuGMfa8pY559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:FC4699859D37C353|rigid:Cit4wMzlELVTt5iY+QuQ5yMQ0vM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:P53832 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-2055941|uniprotkb:D6W0R1|ensemblfungi:YNL283C psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:wsc2_yeast(display_long)|uniprotkb:YNL283C(locus name)|uniprotkb:N0583(orf name)|uniprotkb:WSC2(gene name)|psi-mi:WSC2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338439|imex:IM-14275-2228 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 refseq:NP_014116.1|sgd:S000005227|interpro:IPR002889(Carbohydrate-binding WSC)|mint:P53832|ensemblfungi:YNL283C(gene)|ensemblfungi:YNL283C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip) psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:5wadvTv6SxcIAb60yfnuGMfa8pY559292 intact-crc:B2769E783487940E|rigid:C2btiMTKPRSNA5pCkMQ5OUTVYQw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P53832 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-2055941|uniprotkb:D6W0R1|ensemblfungi:YNL283C psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:wsc2_yeast(display_long)|uniprotkb:YNL283C(locus name)|uniprotkb:N0583(orf name)|uniprotkb:WSC2(gene name)|psi-mi:WSC2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338450|imex:IM-14275-2229 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_014116.1|sgd:S000005227|interpro:IPR002889(Carbohydrate-binding WSC)|mint:P53832|ensemblfungi:YNL283C(gene)|ensemblfungi:YNL283C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:5wadvTv6SxcIAb60yfnuGMfa8pY559292 intact-crc:F26D6E5BDB5AA693|rigid:nukbfJa4l9yxGObQycVJ+6xvM7w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12335 uniprotkb:P53832 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 intact:EBI-2055941|uniprotkb:D6W0R1|ensemblfungi:YNL283C psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:wsc2_yeast(display_long)|uniprotkb:YNL283C(locus name)|uniprotkb:N0583(orf name)|uniprotkb:WSC2(gene name)|psi-mi:WSC2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338461|imex:IM-14275-2230 author score:87.56 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N refseq:NP_014116.1|sgd:S000005227|interpro:IPR002889(Carbohydrate-binding WSC)|mint:P53832|ensemblfungi:YNL283C(gene)|ensemblfungi:YNL283C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip) psi-mi:"MI:0469"(intact) crc64:1056E7A1F3E82288 - figure legend:tables S3 and S4|author-confidence:87.56|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 rogid:5wadvTv6SxcIAb60yfnuGMfa8pY559292 intact-crc:F9F4FC04BD7651B4|rigid:a4TF36z4QOfP7+btG320BjH6LJU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35732 uniprotkb:P53834 intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C intact:EBI-28288|uniprotkb:D6W0R3|ensemblfungi:YNL281W psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:hch1_yeast(display_long)|uniprotkb:HCH1(gene name)|psi-mi:HCH1(display_short)|uniprotkb:YNL281W(locus name)|uniprotkb:N0589(orf name)|uniprotkb:High-copy Hsp90 suppressor protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338472|imex:IM-14275-2231 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 refseq:NP_014118.1|sgd:S000005225|dip:DIP-4395N|mint:P53834|ensemblfungi:YNL281W(gene)|ensemblfungi:YNL281W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR015310(Activator of Hsp90 ATPase, N-terminal)|interpro:IPR036338|interpro:IPR039981 psi-mi:"MI:0469"(intact) crc64:05734E2D0B7389AC crc64:DAD84DBF9BF5DC9F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 rogid:f1gS31qqt1jGRycD4GVoWw043Cs559292 intact-crc:551DBEE91A1FBB52|rigid:V3rAjwIxT7N1Wy50MQaYP683DSA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38009 uniprotkb:P53834 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 intact:EBI-28288|uniprotkb:D6W0R3|ensemblfungi:YNL281W psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:hch1_yeast(display_long)|uniprotkb:HCH1(gene name)|psi-mi:HCH1(display_short)|uniprotkb:YNL281W(locus name)|uniprotkb:N0589(orf name)|uniprotkb:High-copy Hsp90 suppressor protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338483|imex:IM-14275-2232 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N refseq:NP_014118.1|sgd:S000005225|dip:DIP-4395N|mint:P53834|ensemblfungi:YNL281W(gene)|ensemblfungi:YNL281W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR015310(Activator of Hsp90 ATPase, N-terminal)|interpro:IPR036338|interpro:IPR039981 psi-mi:"MI:0469"(intact) crc64:8ABA71761B512242 crc64:DAD84DBF9BF5DC9F figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 rogid:f1gS31qqt1jGRycD4GVoWw043Cs559292 intact-crc:22C0B58C33A15AE3|rigid:fKFXVRQLlr5r1l80b9PAyVrJdsA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53839 uniprotkb:P41811 intact:EBI-28263|uniprotkb:D6W0S0|ensemblfungi:YNL274C intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:gor1_yeast(display_long)|uniprotkb:N0631(orf name)|uniprotkb:YNL274C(locus name)|uniprotkb:GOR1(gene name)|psi-mi:GOR1(display_short) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338494|imex:IM-14275-2233 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029752|interpro:IPR029753|refseq:NP_014125.1|sgd:S000005218|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|mint:P53839|interpro:IPR036291|ensemblfungi:YNL274C(gene)|ensemblfungi:YNL274C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0009436"(glyoxylate catabolic process)|go:"GO:0016618"(hydroxypyruvate reductase activity)|go:"GO:0030267"("glyoxylate reductase (NADP+) activity")|go:"GO:0047964"("glyoxylate reductase (NAD+) activity")|go:"GO:0051287"(NAD binding) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - crc64:6A5E50BBEB02CB58 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2JjlqdpikNnH78krdZtcEnjAf+0559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:F27A29036E52FE4E|rigid:TpYMNerCdDmi1PvLshSDfzeltAg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53843 uniprotkb:P53843 intact:EBI-28245|uniprotkb:D6W0S8|ensemblfungi:YNL265C intact:EBI-28245|uniprotkb:D6W0S8|ensemblfungi:YNL265C psi-mi:ist1_yeast(display_long)|uniprotkb:YNL265C(locus name)|uniprotkb:N0809(orf name)|uniprotkb:IST1(gene name)|psi-mi:IST1(display_short)|uniprotkb:Increased sodium tolerance protein 1(gene name synonym) psi-mi:ist1_yeast(display_long)|uniprotkb:YNL265C(locus name)|uniprotkb:N0809(orf name)|uniprotkb:IST1(gene name)|psi-mi:IST1(display_short)|uniprotkb:Increased sodium tolerance protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338505|imex:IM-14275-2234 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014134.1|sgd:S000005209|dip:DIP-6713N|mint:P53843|ensemblfungi:YNL265C(gene)|ensemblfungi:YNL265C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|interpro:IPR005061(Protein of unknown function DUF292, eukaryotic)|interpro:IPR042277|rcsb pdb:3GGY|rcsb pdb:3GGZ|reactome:R-SCE-6798695|reactome:R-SCE-9668328 refseq:NP_014134.1|sgd:S000005209|dip:DIP-6713N|mint:P53843|ensemblfungi:YNL265C(gene)|ensemblfungi:YNL265C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|interpro:IPR005061(Protein of unknown function DUF292, eukaryotic)|interpro:IPR042277|rcsb pdb:3GGY|rcsb pdb:3GGZ|reactome:R-SCE-6798695|reactome:R-SCE-9668328 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:c8ngH6tobftaOGIxLH8qXiOpi28559292 rogid:c8ngH6tobftaOGIxLH8qXiOpi28559292 intact-crc:F3371033EB37EF56|rigid:pIDFAOeqtU+uEP6jhCA/RxWuyCM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P69771 uniprotkb:P53843 intact:EBI-2053489|uniprotkb:D6VX98|ensemblfungi:YKR035W-A intact:EBI-28245|uniprotkb:D6W0S8|ensemblfungi:YNL265C psi-mi:did2_yeast(display_long)|uniprotkb:CHM1(gene name synonym)|uniprotkb:FTI1(gene name synonym)|uniprotkb:Fifty two inhibitor 1(gene name synonym)|uniprotkb:YKR035W-A(locus name)|uniprotkb:VPS46(gene name synonym)|uniprotkb:Charged multivesicular body protein 1(gene name synonym)|uniprotkb:DOA4-independent degradation protein 2(gene name synonym)|uniprotkb:DID2(gene name)|psi-mi:DID2(display_short) psi-mi:ist1_yeast(display_long)|uniprotkb:YNL265C(locus name)|uniprotkb:N0809(orf name)|uniprotkb:IST1(gene name)|psi-mi:IST1(display_short)|uniprotkb:Increased sodium tolerance protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338516|imex:IM-14275-2235 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006435|refseq:NP_012961.3|dip:DIP-52223N|mint:P69771|ensemblfungi:YKR035W-A(gene)|ensemblfungi:YKR035W-A_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|rcsb pdb:3GGZ|rcsb pdb:5H7P refseq:NP_014134.1|sgd:S000005209|dip:DIP-6713N|mint:P53843|ensemblfungi:YNL265C(gene)|ensemblfungi:YNL265C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|interpro:IPR005061(Protein of unknown function DUF292, eukaryotic)|interpro:IPR042277|rcsb pdb:3GGY|rcsb pdb:3GGZ|reactome:R-SCE-6798695|reactome:R-SCE-9668328 psi-mi:"MI:0469"(intact) crc64:70D1CF4588A8C6E6 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SVI1+8lRI6qwD0CSLY11Xq0LG0o559292 rogid:c8ngH6tobftaOGIxLH8qXiOpi28559292 intact-crc:892D4734F8F6F97C|rigid:B99gmwNEnTICzDD4Ci/ZeLVO5gg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06263 uniprotkb:P53843 intact:EBI-37098|uniprotkb:Q07057|uniprotkb:D6VYI5|ensemblfungi:YLR181C intact:EBI-28245|uniprotkb:D6W0S8|ensemblfungi:YNL265C psi-mi:vta1_yeast(display_long)|uniprotkb:VTA1(gene name)|psi-mi:VTA1(display_short)|uniprotkb:YLR181C(locus name)|uniprotkb:VPS20-associated protein 1(gene name synonym) psi-mi:ist1_yeast(display_long)|uniprotkb:YNL265C(locus name)|uniprotkb:N0809(orf name)|uniprotkb:IST1(gene name)|psi-mi:IST1(display_short)|uniprotkb:Increased sodium tolerance protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338527|imex:IM-14275-2236 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013282.1|sgd:S000004171|mint:Q06263|dip:DIP-4802N|ensemblfungi:YLR181C(gene)|ensemblfungi:YLR181C_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0006869"(lipid transport)|go:"GO:0015031"(protein transport)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR023175|interpro:IPR039431|interpro:IPR041212|interpro:IPR044538|rcsb pdb:2LUH|rcsb pdb:2RKK|rcsb pdb:2RKL|rcsb pdb:3MHV|rcsb pdb:5H7P|rcsb pdb:5UIE|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6OO2|reactome:R-SCE-917729 refseq:NP_014134.1|sgd:S000005209|dip:DIP-6713N|mint:P53843|ensemblfungi:YNL265C(gene)|ensemblfungi:YNL265C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|interpro:IPR005061(Protein of unknown function DUF292, eukaryotic)|interpro:IPR042277|rcsb pdb:3GGY|rcsb pdb:3GGZ|reactome:R-SCE-6798695|reactome:R-SCE-9668328 psi-mi:"MI:0469"(intact) crc64:BB6E6975596C1674 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:X9sRQb1nZECFkdjvDUTjxEgokRM559292 rogid:c8ngH6tobftaOGIxLH8qXiOpi28559292 intact-crc:81229915C52443A7|rigid:TkFs02mryl6ajP8lA3Fx3MMQKkU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24783 uniprotkb:P53849 intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W intact:EBI-29244|uniprotkb:D6W0T8|ensemblfungi:YNL255C psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:gis2_yeast(display_long)|uniprotkb:GIS2(gene name)|psi-mi:GIS2(display_short)|uniprotkb:N0852(orf name)|uniprotkb:YNL255C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338538|imex:IM-14275-2237 author score:93.71 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 refseq:NP_014144.1|sgd:S000005199|dip:DIP-2669N|mint:P53849|ensemblfungi:YNL255C(gene)|ensemblfungi:YNL255C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045182"(translation regulator activity)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875 psi-mi:"MI:0469"(intact) crc64:30FE3D4C7E653120 crc64:E72696428F85CA3F figure legend:tables S3 and S4|author-confidence:93.71|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 rogid:kftHFJVi7QRZASmr4hLdALvleR4559292 intact-crc:76FF4ACD8FD479F8|rigid:kbIsBi/Vy6WmmSlyAEJbxFkOUaM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53849 uniprotkb:P24784 intact:EBI-29244|uniprotkb:D6W0T8|ensemblfungi:YNL255C intact:EBI-5596|uniprotkb:P20446|uniprotkb:D6W3P9|ensemblfungi:YPL119C psi-mi:gis2_yeast(display_long)|uniprotkb:GIS2(gene name)|psi-mi:GIS2(display_short)|uniprotkb:N0852(orf name)|uniprotkb:YNL255C(locus name) psi-mi:dbp1_yeast(display_long)|uniprotkb:DBP1(gene name)|psi-mi:DBP1(display_short)|uniprotkb:YPL119C(locus name)|uniprotkb:LPH8C(orf name)|uniprotkb:DEAD box protein 1(gene name synonym)|uniprotkb:Helicase CA1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338549|imex:IM-14275-2238 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014144.1|sgd:S000005199|dip:DIP-2669N|mint:P53849|ensemblfungi:YNL255C(gene)|ensemblfungi:YNL255C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045182"(translation regulator activity)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875 refseq:NP_015206.1|sgd:S000006040|dip:DIP-2576N|mint:P24784|ensemblfungi:YPL119C(gene)|ensemblfungi:YPL119C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763 psi-mi:"MI:0469"(intact) crc64:E72696428F85CA3F - figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kftHFJVi7QRZASmr4hLdALvleR4559292 rogid:8TFwSQq3dopTasOH0G/KZ12DDGE559292 intact-crc:71FEFEC2B2E8B036|rigid:79otDbGq1rkBtnrvnyEQXPylWWU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53849 uniprotkb:P25567 intact:EBI-29244|uniprotkb:D6W0T8|ensemblfungi:YNL255C intact:EBI-18084|uniprotkb:D6VQX8|ensemblfungi:YCL037C psi-mi:gis2_yeast(display_long)|uniprotkb:GIS2(gene name)|psi-mi:GIS2(display_short)|uniprotkb:N0852(orf name)|uniprotkb:YNL255C(locus name) psi-mi:sro9_yeast(display_long)|uniprotkb:SRO9(gene name)|psi-mi:SRO9(display_short)|uniprotkb:YCL037C(locus name)|uniprotkb:YCL37C(orf name)|uniprotkb:Suppressor of RHO3 protein 9(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338560|imex:IM-14275-2239 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014144.1|sgd:S000005199|dip:DIP-2669N|mint:P53849|ensemblfungi:YNL255C(gene)|ensemblfungi:YNL255C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045182"(translation regulator activity)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875 refseq:NP_009893.2|sgd:S000000542|ensemblfungi:YCL037C(gene)|ensemblfungi:YCL037C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|dip:DIP-6638N|mint:P25567 psi-mi:"MI:0469"(intact) crc64:E72696428F85CA3F crc64:B1B720D40C7B9914 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kftHFJVi7QRZASmr4hLdALvleR4559292 rogid:CouwiBsK7S3Tm6CoBsu3LdWfelg559292 intact-crc:DA90D3AE4ABFBF2D|rigid:KMZrfFxlf23HDT7Pbu0T5N5jWp4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38009 uniprotkb:P53849 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 intact:EBI-29244|uniprotkb:D6W0T8|ensemblfungi:YNL255C psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:gis2_yeast(display_long)|uniprotkb:GIS2(gene name)|psi-mi:GIS2(display_short)|uniprotkb:N0852(orf name)|uniprotkb:YNL255C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338571|imex:IM-14275-2240 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N refseq:NP_014144.1|sgd:S000005199|dip:DIP-2669N|mint:P53849|ensemblfungi:YNL255C(gene)|ensemblfungi:YNL255C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045182"(translation regulator activity)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875 psi-mi:"MI:0469"(intact) crc64:8ABA71761B512242 crc64:E72696428F85CA3F figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 rogid:kftHFJVi7QRZASmr4hLdALvleR4559292 intact-crc:18CBE192554F42D8|rigid:bfT5Fb/Fc06477ZFIxdeLV2gqDw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38998 uniprotkb:P53849 intact:EBI-10264|uniprotkb:D6VVW5|ensemblfungi:YIR034C intact:EBI-29244|uniprotkb:D6W0T8|ensemblfungi:YNL255C psi-mi:lys1_yeast(display_long)|uniprotkb:LYS1(gene name)|psi-mi:LYS1(display_short)|uniprotkb:Lysine--2-oxoglutarate reductase(gene name synonym)|uniprotkb:YIR034C(locus name) psi-mi:gis2_yeast(display_long)|uniprotkb:GIS2(gene name)|psi-mi:GIS2(display_short)|uniprotkb:N0852(orf name)|uniprotkb:YNL255C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338582|imex:IM-14275-2241 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001473|ensemblfungi:YIR034C(gene)|ensemblfungi:YIR034C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004754"("saccharopine dehydrogenase (NAD+, L-lysine-forming) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0009085"(lysine biosynthetic process)|go:"GO:0019878"(lysine biosynthetic process via aminoadipic acid)|interpro:IPR007698(Alanine dehydrogenase/PNT, C-terminal)|interpro:IPR007886(Alanine dehydrogenase/PNT, N-terminal)|interpro:IPR027281|interpro:IPR036291|rcsb pdb:2Q99|rcsb pdb:2QRJ|rcsb pdb:2QRK|rcsb pdb:2QRL|rcsb pdb:3UGK|rcsb pdb:3UH1|rcsb pdb:3UHA|refseq:NP_012300.3|dip:DIP-5291N|mint:P38998 refseq:NP_014144.1|sgd:S000005199|dip:DIP-2669N|mint:P53849|ensemblfungi:YNL255C(gene)|ensemblfungi:YNL255C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045182"(translation regulator activity)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875 psi-mi:"MI:0469"(intact) crc64:7E3A810876C1DC41 crc64:E72696428F85CA3F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:J4J9INV+EPP8QnEbWcbzbz5/Op4559292 rogid:kftHFJVi7QRZASmr4hLdALvleR4559292 intact-crc:14368896C8F13975|rigid:knPZIocIv9Rk2/jpbCiw40gbmQc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53849 uniprotkb:P40070 intact:EBI-29244|uniprotkb:D6W0T8|ensemblfungi:YNL255C intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W psi-mi:gis2_yeast(display_long)|uniprotkb:GIS2(gene name)|psi-mi:GIS2(display_short)|uniprotkb:N0852(orf name)|uniprotkb:YNL255C(locus name) psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338593|imex:IM-14275-2242 author score:93.71 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014144.1|sgd:S000005199|dip:DIP-2669N|mint:P53849|ensemblfungi:YNL255C(gene)|ensemblfungi:YNL255C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045182"(translation regulator activity)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875 sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 psi-mi:"MI:0469"(intact) crc64:E72696428F85CA3F crc64:69CAC1F01D5BFA98 figure legend:tables S3 and S4|author-confidence:93.71|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kftHFJVi7QRZASmr4hLdALvleR4559292 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 intact-crc:3C2BD627349851B7|rigid:/NqFxhbEfDnU4Khi8rv20gQuQ4c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53235 uniprotkb:P53849 intact:EBI-23172|uniprotkb:D6VUI9|uniprotkb:Q45U32|ensemblfungi:YGR054W intact:EBI-29244|uniprotkb:D6W0T8|ensemblfungi:YNL255C psi-mi:eif2a_yeast(display_long)|uniprotkb:YGR054W(locus name) psi-mi:gis2_yeast(display_long)|uniprotkb:GIS2(gene name)|psi-mi:GIS2(display_short)|uniprotkb:N0852(orf name)|uniprotkb:YNL255C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338604|imex:IM-14275-2243 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003286|refseq:NP_011568.3|dip:DIP-5518N|mint:P53235|ensemblfungi:YGR054W(gene)|ensemblfungi:YGR054W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like) refseq:NP_014144.1|sgd:S000005199|dip:DIP-2669N|mint:P53849|ensemblfungi:YNL255C(gene)|ensemblfungi:YNL255C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045182"(translation regulator activity)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875 psi-mi:"MI:0469"(intact) crc64:F3C2E78504D83418 crc64:E72696428F85CA3F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:x8zDCH5W5GusC7qYd0mDATXhGVI559292 rogid:kftHFJVi7QRZASmr4hLdALvleR4559292 intact-crc:30CE6F6D011B39AC|rigid:HPiuGydc1K19TStzhsSnRQ4xjdw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53849 uniprotkb:P53741 intact:EBI-29244|uniprotkb:D6W0T8|ensemblfungi:YNL255C intact:EBI-28528|uniprotkb:D6W1M6|ensemblfungi:YNR051C psi-mi:gis2_yeast(display_long)|uniprotkb:GIS2(gene name)|psi-mi:GIS2(display_short)|uniprotkb:N0852(orf name)|uniprotkb:YNL255C(locus name) psi-mi:bre5_yeast(display_long)|uniprotkb:BRE5(gene name)|psi-mi:BRE5(display_short)|uniprotkb:YNR051C(locus name)|uniprotkb:N3465(orf name)|uniprotkb:Brefeldin-A sensitivity protein 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338615|imex:IM-14275-2244 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014144.1|sgd:S000005199|dip:DIP-2669N|mint:P53849|ensemblfungi:YNL255C(gene)|ensemblfungi:YNL255C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045182"(translation regulator activity)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875 refseq:NP_014449.1|sgd:S000005334|dip:DIP-4254N|mint:P53741|ensemblfungi:YNR051C(gene)|ensemblfungi:YNR051C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0034517"(ribophagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1990861"(Ubp3-Bre5 deubiquitination complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000156"(regulation of retrograde vesicle-mediated transport, Golgi to ER)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710|interpro:IPR039539|rcsb pdb:1ZX2|rcsb pdb:2QIY psi-mi:"MI:0469"(intact) crc64:E72696428F85CA3F - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kftHFJVi7QRZASmr4hLdALvleR4559292 rogid:DIP3qqPEixSKoo2gi7O9Zsrj7wk559292 intact-crc:1DBB8A7FEBD97CF2|rigid:R2bZbUYh+/bu6SchWTK73vfbAj0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53849 uniprotkb:P53849 intact:EBI-29244|uniprotkb:D6W0T8|ensemblfungi:YNL255C intact:EBI-29244|uniprotkb:D6W0T8|ensemblfungi:YNL255C psi-mi:gis2_yeast(display_long)|uniprotkb:GIS2(gene name)|psi-mi:GIS2(display_short)|uniprotkb:N0852(orf name)|uniprotkb:YNL255C(locus name) psi-mi:gis2_yeast(display_long)|uniprotkb:GIS2(gene name)|psi-mi:GIS2(display_short)|uniprotkb:N0852(orf name)|uniprotkb:YNL255C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338626|imex:IM-14275-2245 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014144.1|sgd:S000005199|dip:DIP-2669N|mint:P53849|ensemblfungi:YNL255C(gene)|ensemblfungi:YNL255C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045182"(translation regulator activity)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875 refseq:NP_014144.1|sgd:S000005199|dip:DIP-2669N|mint:P53849|ensemblfungi:YNL255C(gene)|ensemblfungi:YNL255C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045182"(translation regulator activity)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875 psi-mi:"MI:0469"(intact) crc64:E72696428F85CA3F crc64:E72696428F85CA3F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kftHFJVi7QRZASmr4hLdALvleR4559292 rogid:kftHFJVi7QRZASmr4hLdALvleR4559292 intact-crc:9B8D5F621E4253CC|rigid:2XICM7s27XFmezasiLJtdmau+1M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53852 uniprotkb:P53852 intact:EBI-29230|uniprotkb:D6W0U6|ensemblfungi:YNL247W intact:EBI-29230|uniprotkb:D6W0U6|ensemblfungi:YNL247W psi-mi:syc_yeast(display_long)|uniprotkb:Cysteinyl-tRNA synthetase(gene name synonym)|uniprotkb:N0885(orf name)|uniprotkb:YNL247W(locus name) psi-mi:syc_yeast(display_long)|uniprotkb:Cysteinyl-tRNA synthetase(gene name synonym)|uniprotkb:N0885(orf name)|uniprotkb:YNL247W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338637|imex:IM-14275-2246 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024909|refseq:NP_014152.1|sgd:S000005191|interpro:IPR015803(Cysteinyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR032678|mint:P53852|ensemblfungi:YNL247W(gene)|ensemblfungi:YNL247W_mRNA(transcript)|go:"GO:0004817"(cysteine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006423"(cysteinyl-tRNA aminoacylation)|go:"GO:0046872"(metal ion binding) interpro:IPR024909|refseq:NP_014152.1|sgd:S000005191|interpro:IPR015803(Cysteinyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR032678|mint:P53852|ensemblfungi:YNL247W(gene)|ensemblfungi:YNL247W_mRNA(transcript)|go:"GO:0004817"(cysteine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006423"(cysteinyl-tRNA aminoacylation)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:yNdPUrnNWXwsHCz54YW9uNn9T8o559292 rogid:yNdPUrnNWXwsHCz54YW9uNn9T8o559292 intact-crc:73B0A21A5122A486|rigid:jevxLyQqVtJS1VAPguMmDf4rFpA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53872 uniprotkb:P53262 intact:EBI-29075|uniprotkb:D6W0Z7|ensemblfungi:YNL190W intact:EBI-2061527|uniprotkb:D6VUN8|ensemblfungi:YGR106C psi-mi:pga14_yeast(display_long)|uniprotkb:N1415(orf name)|uniprotkb:YNL190W(locus name) psi-mi:voa1_yeast(display_long)|uniprotkb:YGR106C(locus name)|uniprotkb:VOA1(gene name)|psi-mi:VOA1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338648|imex:IM-14275-2247 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005134|refseq:NP_014209.1|dip:DIP-4739N|mint:P53872|ensemblfungi:YNL190W(gene)|ensemblfungi:YNL190W_mRNA(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0042631"(cellular response to water deprivation) sgd:S000003338|refseq:NP_011620.1|mint:P53262|ensemblfungi:YGR106C(gene)|ensemblfungi:YGR106C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034622"|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|rcsb pdb:6PE4|rcsb pdb:6PE5 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FMyZikI+ur2JPlHqiwX3O2KrmbA559292 rogid:lKLIonttSEX36IQaIKlzxS/Cdxg559292 intact-crc:3BC8E0340EEF6323|rigid:AY1jazvY47PIehGb0cJfYDA2isY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06144 uniprotkb:P53872 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W intact:EBI-29075|uniprotkb:D6W0Z7|ensemblfungi:YNL190W psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:pga14_yeast(display_long)|uniprotkb:N1415(orf name)|uniprotkb:YNL190W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338659|imex:IM-14275-2248 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 sgd:S000005134|refseq:NP_014209.1|dip:DIP-4739N|mint:P53872|ensemblfungi:YNL190W(gene)|ensemblfungi:YNL190W_mRNA(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0042631"(cellular response to water deprivation) psi-mi:"MI:0469"(intact) crc64:2F474503CAB7C195 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 rogid:FMyZikI+ur2JPlHqiwX3O2KrmbA559292 intact-crc:ECE23A3EDD764C43|rigid:BNyLZhq5GX4ft7r3tRSSQucg2A0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07500 uniprotkb:P53873 intact:EBI-38178|uniprotkb:D6VRR4|ensemblfungi:YDL085W intact:EBI-29071|uniprotkb:D6W100|ensemblfungi:YNL187W psi-mi:ndh2_yeast(display_long)|uniprotkb:NDE2(gene name)|psi-mi:NDE2(display_short)|uniprotkb:NDH2(gene name synonym)|uniprotkb:YDL085W(locus name)|uniprotkb:External NADH dehydrogenase 2(gene name synonym) psi-mi:swt21_yeast(display_long)|uniprotkb:YNL187W(locus name)|uniprotkb:N1615(orf name)|uniprotkb:SWT21(gene name)|psi-mi:SWT21(display_short)|uniprotkb:Synthetic With TGS1 protein 21(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338670|imex:IM-14275-2249 author score:97.40 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010198.1|sgd:S000002243|mint:Q07500|dip:DIP-5023N|ensemblfungi:YDL085W(gene)|ensemblfungi:YDL085W_mRNA(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006116"(NADH oxidation)|go:"GO:0019655"(glycolytic fermentation to ethanol)|go:"GO:0050136"("NADH dehydrogenase (quinone) activity")|interpro:IPR023753|interpro:IPR036188 refseq:NP_014212.1|sgd:S000005131|dip:DIP-971N|mint:P53873|ensemblfungi:YNL187W(gene)|ensemblfungi:YNL187W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322 psi-mi:"MI:0469"(intact) crc64:291E81D0FC6D3FD7 - figure legend:tables S3 and S4|author-confidence:97.40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VDKbGYjFURtBVpghiIp4aKVVAfI559292 rogid:mRhWh6yiKqNuDswD3M90vtak7lo559292 intact-crc:E482DBF5F2FACDDF|rigid:zbCwowca3nfQiioLrMmQqkpUv+Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53874 uniprotkb:P53874 intact:EBI-19873|uniprotkb:D6W101|ensemblfungi:YNL186W intact:EBI-19873|uniprotkb:D6W101|ensemblfungi:YNL186W psi-mi:ubp10_yeast(display_long)|uniprotkb:UBP10(gene name)|psi-mi:UBP10(display_short)|uniprotkb:YNL186W(locus name)|uniprotkb:N1619(orf name)|uniprotkb:Ubiquitin-specific-processing protease 10(gene name synonym)|uniprotkb:Deubiquitinating enzyme 10(gene name synonym)|uniprotkb:Disrupter of telomere silencing protein 4(gene name synonym)|uniprotkb:Ubiquitin thioesterase 10(gene name synonym)|uniprotkb:DOT4(gene name synonym) psi-mi:ubp10_yeast(display_long)|uniprotkb:UBP10(gene name)|psi-mi:UBP10(display_short)|uniprotkb:YNL186W(locus name)|uniprotkb:N1619(orf name)|uniprotkb:Ubiquitin-specific-processing protease 10(gene name synonym)|uniprotkb:Deubiquitinating enzyme 10(gene name synonym)|uniprotkb:Disrupter of telomere silencing protein 4(gene name synonym)|uniprotkb:Ubiquitin thioesterase 10(gene name synonym)|uniprotkb:DOT4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338681|imex:IM-14275-2250 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014213.2|sgd:S000005130|ensemblfungi:YNL186W(gene)|ensemblfungi:YNL186W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0043596"(nuclear replication fork)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|rcsb pdb:6RR0|dip:DIP-6664N|mint:P53874 refseq:NP_014213.2|sgd:S000005130|ensemblfungi:YNL186W(gene)|ensemblfungi:YNL186W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0043596"(nuclear replication fork)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|rcsb pdb:6RR0|dip:DIP-6664N|mint:P53874 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Z1rRAI9RLgHeGd7QwLbrf51v5LY559292 rogid:Z1rRAI9RLgHeGd7QwLbrf51v5LY559292 intact-crc:685BEAC3473F2B7C|rigid:QKzdc0n0OQeMGHj8wTzcoihuujw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38996 uniprotkb:P53877 intact:EBI-11776|uniprotkb:Q07034|ensemblfungi:YPL190C|uniprotkb:D6W3H8 intact:EBI-29063|uniprotkb:D6W104|ensemblfungi:YNL182C psi-mi:nab3_yeast(display_long)|uniprotkb:YPL190C(locus name)|uniprotkb:NAB3(gene name)|psi-mi:NAB3(display_short)|uniprotkb:HMD1(gene name synonym) psi-mi:ipi3_yeast(display_long)|uniprotkb:Involved in processing IST2 protein 3(gene name synonym)|uniprotkb:YNL182C(locus name)|uniprotkb:N1636(orf name)|uniprotkb:IPI3(gene name)|psi-mi:IPI3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338692|imex:IM-14275-2251 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036621|rcsb pdb:2KVI|rcsb pdb:2L41|interpro:IPR035979|rcsb pdb:2XNQ|rcsb pdb:2XNR|ensemblfungi:YPL190C(gene)|ensemblfungi:YPL190C_mRNA(transcript)|go:"GO:0001068"(transcription regulatory region RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0030847"(termination of RNA polymerase II transcription, exosome-dependent)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0034472"(snRNA 3'-end processing)|go:"GO:0035649"(Nrd1 complex)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071041"(antisense RNA transcript catabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034167|refseq:NP_015134.1|sgd:S000006111|mint:P38996|dip:DIP-3980N refseq:NP_014217.1|sgd:S000005126|dip:DIP-4297N|mint:P53877|ensemblfungi:YNL182C(gene)|ensemblfungi:YNL182C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006364"(rRNA processing)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0097344"(Rix1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:6YLE|rcsb pdb:6YLH|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:CD6D2C7F24A44993 crc64:8EED6854DF9405A6 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iVBA824UReQJmvua7xganVlrm9U559292 rogid:TnWhNydR8/R7o8z+P9PGGngpJQk559292 intact-crc:4588228035DD8156|rigid:lMltFNrSH08b6PuoEh2Gps1SiDM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40350 uniprotkb:P53877 intact:EBI-2470|uniprotkb:D6W3E3|ensemblfungi:YPL227C intact:EBI-29063|uniprotkb:D6W104|ensemblfungi:YNL182C psi-mi:alg5_yeast(display_long)|uniprotkb:ALG5(gene name)|psi-mi:ALG5(display_short)|uniprotkb:YPL227C(locus name)|uniprotkb:P1437(orf name)|uniprotkb:Asparagine-linked glycosylation protein 5(gene name synonym) psi-mi:ipi3_yeast(display_long)|uniprotkb:Involved in processing IST2 protein 3(gene name synonym)|uniprotkb:YNL182C(locus name)|uniprotkb:N1636(orf name)|uniprotkb:IPI3(gene name)|psi-mi:IPI3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338703|imex:IM-14275-2252 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015097.1|sgd:S000006148|dip:DIP-5651N|mint:P40350|ensemblfungi:YPL227C(gene)|ensemblfungi:YPL227C_mRNA(transcript)|go:"GO:0004581"(dolichyl-phosphate beta-glucosyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR035518|reactome:R-SCE-480985 refseq:NP_014217.1|sgd:S000005126|dip:DIP-4297N|mint:P53877|ensemblfungi:YNL182C(gene)|ensemblfungi:YNL182C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006364"(rRNA processing)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0097344"(Rix1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:6YLE|rcsb pdb:6YLH|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) - crc64:8EED6854DF9405A6 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aKi97cbwqo7kNWhtRyzG3UOLH4U559292 rogid:TnWhNydR8/R7o8z+P9PGGngpJQk559292 intact-crc:5E6AEAAFAAFA4EB2|rigid:aH3pZFGWLpXUjp3Zp9j1KOmnSRc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53879 uniprotkb:P38634 intact:EBI-29054|uniprotkb:D6W106|ensemblfungi:YNL180C intact:EBI-17127|ensemblfungi:YLR079W|uniprotkb:D6VY79 psi-mi:rho5_yeast(display_long)|uniprotkb:RHO5(gene name)|psi-mi:RHO5(display_short)|uniprotkb:N1644(orf name)|uniprotkb:YNL180C(locus name) psi-mi:sic1_yeast(display_long)|uniprotkb:SIC1(gene name)|psi-mi:SIC1(display_short)|uniprotkb:SDB25(gene name synonym)|uniprotkb:YLR079W(locus name)|uniprotkb:L9449.8(orf name)|uniprotkb:CDK inhibitor p40(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338714|imex:IM-14275-2253 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014219.1|sgd:S000005124|dip:DIP-2874N|mint:P53879|ensemblfungi:YNL180C(gene)|ensemblfungi:YNL180C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0012505"(endomembrane system)|go:"GO:0030031"(cell projection assembly)|go:"GO:0032488"(Cdc42 protein signal transduction)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-SCE-9013423 ensemblfungi:YLR079W(gene)|ensemblfungi:YLR079W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016242"(negative regulation of macroautophagy)|rcsb pdb:3V7D|rcsb pdb:6G86|refseq:NP_013180.1|sgd:S000004069|dip:DIP-6817N|mint:P38634 psi-mi:"MI:0469"(intact) crc64:EEAFD4E39E7ACF81 crc64:7913636340678F78 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:LkK90AxZANdZRAnBbqqpCH7bnBs559292 rogid:qU8ivBCZHvG4VmXDxv52yc08Hwc559292 intact-crc:41EB6CBC901E60DD|rigid:LkVj1Ie1oRbDoDa42y4e3EotCpE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53890 uniprotkb:P53890 intact:EBI-28997|uniprotkb:D6W116|ensemblfungi:YNL166C intact:EBI-28997|uniprotkb:D6W116|ensemblfungi:YNL166C psi-mi:bni5_yeast(display_long)|uniprotkb:BNI5(gene name)|psi-mi:BNI5(display_short)|uniprotkb:N1706(orf name)|uniprotkb:YNL166C(locus name) psi-mi:bni5_yeast(display_long)|uniprotkb:BNI5(gene name)|psi-mi:BNI5(display_short)|uniprotkb:N1706(orf name)|uniprotkb:YNL166C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338725|imex:IM-14275-2254 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005110|refseq:NP_014233.1|dip:DIP-4333N|mint:P53890|ensemblfungi:YNL166C(gene)|ensemblfungi:YNL166C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000921"(septin ring assembly)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007049"(cell cycle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032035"(myosin II tail binding)|go:"GO:0072741"(protein localization to cell division site) sgd:S000005110|refseq:NP_014233.1|dip:DIP-4333N|mint:P53890|ensemblfungi:YNL166C(gene)|ensemblfungi:YNL166C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000921"(septin ring assembly)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007049"(cell cycle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032035"(myosin II tail binding)|go:"GO:0072741"(protein localization to cell division site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:NTgxeI/1Vxuh+2iD0XRlV9pqE7g559292 rogid:NTgxeI/1Vxuh+2iD0XRlV9pqE7g559292 intact-crc:77CD982AFE9F7183|rigid:nHLPXraYbyS9lm8KeIG7QhDT+qI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CX10 uniprotkb:P53924 intact:EBI-6315262|ensemblfungi:YOR393W|ensemblfungi:YPL281C|uniprotkb:D6W385|uniprotkb:Q12007|uniprotkb:Q7LGJ4 intact:EBI-28867|uniprotkb:B0KZS8|uniprotkb:B0KZU6|uniprotkb:B0KZW4|uniprotkb:B0L009|uniprotkb:Q66GT0|uniprotkb:D6W166|ensemblfungi:YNL116W psi-mi:err1_yeast(display_long)|uniprotkb:ERR1(gene name)|psi-mi:ERR1(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:2-phosphoglycerate dehydratase(gene name synonym)|uniprotkb:YOR393W(locus name) psi-mi:dma2_yeast(display_long)|uniprotkb:CHF2(gene name synonym)|uniprotkb:DMA2(gene name)|psi-mi:DMA2(display_short)|uniprotkb:Defective in mitotic arrest protein 2(gene name synonym)|uniprotkb:Checkpoint forkhead associated with RING domains-containing protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DMA2(gene name synonym)|uniprotkb:N1925(orf name)|uniprotkb:YNL116W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338736|imex:IM-14275-2255 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR393W(gene)|ensemblfungi:YOR393W_mRNA(transcript)|ensemblfungi:YPL281C(gene)|ensemblfungi:YPL281C_mRNA(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0006096"(glycolytic process)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|reactome:R-SCE-70171|reactome:R-SCE-70263|mint:P0CX10|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|refseq:NP_015038.1|refseq:NP_015042.1|sgd:S000005920|interpro:IPR029017|interpro:IPR036849 sgd:S000005060|refseq:NP_014283.3|dip:DIP-1774N|mint:P53924|ensemblfungi:YNL116W(gene)|ensemblfungi:YNL116W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000921"(septin ring assembly)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0032153"(cell division site)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090337"(regulation of formin-nucleated actin cable assembly)|go:"GO:0097271"(protein localization to bud neck)|go:"GO:1902364"(negative regulation of protein localization to spindle pole body)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042823|reactome:R-SCE-532668 psi-mi:"MI:0469"(intact) - crc64:AE1BD2D617221607 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Vusa5LQZe98ke/mcTRdEnXReZDc559292 rogid:Yiml+05RR3OVAkhB8G0Pudpw6HI559292 intact-crc:AF6ACBA5E6815181|rigid:bVKZyJHN+br8q8UhrkRw9qP3rWI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38779 uniprotkb:P53927 intact:EBI-24538|uniprotkb:D3DL01|ensemblfungi:YHR052W intact:EBI-28853|uniprotkb:D6W171|ensemblfungi:YNL110C psi-mi:cic1_yeast(display_long)|uniprotkb:CIC1(gene name)|psi-mi:CIC1(display_short)|uniprotkb:NSA3(gene name synonym)|uniprotkb:Core interacting component 1(gene name synonym)|uniprotkb:YHR052W(locus name) psi-mi:nop15_yeast(display_long)|uniprotkb:YNL110C(locus name)|uniprotkb:N1954(orf name)|uniprotkb:Nucleolar protein 15(gene name synonym)|uniprotkb:NOP15(gene name)|psi-mi:NOP15(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338747|imex:IM-14275-2256 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011919.1|sgd:S000001094|dip:DIP-6491N|mint:P38779|ensemblfungi:YHR052W(gene)|ensemblfungi:YHR052W_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0019843"(rRNA binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0070628"(proteasome binding)|interpro:IPR023674|interpro:IPR028364|interpro:IPR028365|rcsb pdb:3JCT|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6M62|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BTB|go:"GO:0034513"(box H/ACA snoRNA binding) refseq:NP_014289.1|sgd:S000005054|dip:DIP-4741N|mint:P53927|ensemblfungi:YNL110C(gene)|ensemblfungi:YNL110C_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034469|interpro:IPR035979|rcsb pdb:3JCT|rcsb pdb:5T9P|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6M62|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BTB psi-mi:"MI:0469"(intact) crc64:13A2AFA0B927CD98 crc64:EC86E3C77C863292 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rdhoaLdCr+bDCy9BYwEA9foQFWQ559292 rogid:WHuY5zx7DUsm1G+00Bc6wM8JAJc559292 intact-crc:38AE6CF467B33711|rigid:epEG8U6VRytbLbia1cfvfwuTpOg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06102 uniprotkb:P53935 intact:EBI-12165|uniprotkb:D6VVP4|uniprotkb:Q6B233|ensemblfungi:YIL038C intact:EBI-28788|uniprotkb:Q45TZ3|uniprotkb:D6W189|ensemblfungi:YNL091W psi-mi:not3_yeast(display_long)|uniprotkb:NOT3(gene name)|psi-mi:NOT3(display_short)|uniprotkb:YIL038C(locus name) psi-mi:nst1_yeast(display_long)|uniprotkb:YNL091W(locus name)|uniprotkb:N2231(orf name)|uniprotkb:NST1(gene name)|psi-mi:NST1(display_short)|uniprotkb:Negatively-affecting salt tolerance protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338758|imex:IM-14275-2257 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR038635|interpro:IPR040168|ensemblfungi:YIL038C(gene)|ensemblfungi:YIL038C_mRNA(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|refseq:NP_012226.3|sgd:S000001300|dip:DIP-2256N|mint:P06102 refseq:NP_014308.1|sgd:S000005035|dip:DIP-872N|mint:P53935|ensemblfungi:YNL091W(gene)|ensemblfungi:YNL091W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009651"(response to salt stress)|interpro:IPR025279 psi-mi:"MI:0469"(intact) crc64:69B76694FCC6846F - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:EfakZPDNU3FZeI5+rnu7YV1UsCg559292 rogid:WOSVMqWhtYPlZyt+vfdkpJAHHBg559292 intact-crc:14F7ED849A11C885|rigid:ERngkaPB15leo68FOkxM3DVEedE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53935 uniprotkb:P25655 intact:EBI-28788|uniprotkb:Q45TZ3|uniprotkb:D6W189|ensemblfungi:YNL091W intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W psi-mi:nst1_yeast(display_long)|uniprotkb:YNL091W(locus name)|uniprotkb:N2231(orf name)|uniprotkb:NST1(gene name)|psi-mi:NST1(display_short)|uniprotkb:Negatively-affecting salt tolerance protein 1(gene name synonym) psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338769|imex:IM-14275-2258 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014308.1|sgd:S000005035|dip:DIP-872N|mint:P53935|ensemblfungi:YNL091W(gene)|ensemblfungi:YNL091W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009651"(response to salt stress)|interpro:IPR025279 ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 psi-mi:"MI:0469"(intact) - crc64:5B2AE15BCF95E009 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WOSVMqWhtYPlZyt+vfdkpJAHHBg559292 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 intact-crc:50E175867C2AA110|rigid:hTh+Drc+i9lJkdkpgolADzp8eEU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53935 uniprotkb:P34909 intact:EBI-28788|uniprotkb:Q45TZ3|uniprotkb:D6W189|ensemblfungi:YNL091W intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W psi-mi:nst1_yeast(display_long)|uniprotkb:YNL091W(locus name)|uniprotkb:N2231(orf name)|uniprotkb:NST1(gene name)|psi-mi:NST1(display_short)|uniprotkb:Negatively-affecting salt tolerance protein 1(gene name synonym) psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338780|imex:IM-14275-2259 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014308.1|sgd:S000005035|dip:DIP-872N|mint:P53935|ensemblfungi:YNL091W(gene)|ensemblfungi:YNL091W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009651"(response to salt stress)|interpro:IPR025279 ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 psi-mi:"MI:0469"(intact) - crc64:8847084BD9BF48B7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WOSVMqWhtYPlZyt+vfdkpJAHHBg559292 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 intact-crc:83B04B3F157240E8|rigid:zhdrJ/EhUzG5UHl+DJzZykKMZuE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53935 uniprotkb:P39008 intact:EBI-28788|uniprotkb:Q45TZ3|uniprotkb:D6W189|ensemblfungi:YNL091W intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C psi-mi:nst1_yeast(display_long)|uniprotkb:YNL091W(locus name)|uniprotkb:N2231(orf name)|uniprotkb:NST1(gene name)|psi-mi:NST1(display_short)|uniprotkb:Negatively-affecting salt tolerance protein 1(gene name synonym) psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338791|imex:IM-14275-2260 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014308.1|sgd:S000005035|dip:DIP-872N|mint:P53935|ensemblfungi:YNL091W(gene)|ensemblfungi:YNL091W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009651"(response to salt stress)|interpro:IPR025279 sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N psi-mi:"MI:0469"(intact) - crc64:F3CAF97106A65933 figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WOSVMqWhtYPlZyt+vfdkpJAHHBg559292 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 intact-crc:8ED4D906A82ABDBC|rigid:tjh7+485L68nMe9OktFyYHA/Qu8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53935 uniprotkb:P53829 intact:EBI-28788|uniprotkb:Q45TZ3|uniprotkb:D6W189|ensemblfungi:YNL091W intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W psi-mi:nst1_yeast(display_long)|uniprotkb:YNL091W(locus name)|uniprotkb:N2231(orf name)|uniprotkb:NST1(gene name)|psi-mi:NST1(display_short)|uniprotkb:Negatively-affecting salt tolerance protein 1(gene name synonym) psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338802|imex:IM-14275-2261 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014308.1|sgd:S000005035|dip:DIP-872N|mint:P53935|ensemblfungi:YNL091W(gene)|ensemblfungi:YNL091W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009651"(response to salt stress)|interpro:IPR025279 refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 psi-mi:"MI:0469"(intact) - crc64:F3DBABE6AD3C7F3C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WOSVMqWhtYPlZyt+vfdkpJAHHBg559292 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 intact-crc:13E9A07B5A0C1188|rigid:BFXOfDYFe1caFQAP2Teigpznn/s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53959 uniprotkb:P40094 intact:EBI-4829|uniprotkb:D6W1D8|ensemblfungi:YNL041C intact:EBI-16605|ensemblfungi:YER157W|uniprotkb:D3DM64 psi-mi:cog6_yeast(display_long)|uniprotkb:COG6(gene name)|psi-mi:COG6(display_short)|uniprotkb:COD2(gene name synonym)|uniprotkb:TFI2(gene name synonym)|uniprotkb:YNL041C(locus name)|uniprotkb:N2675(orf name)|uniprotkb:SEC37(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 6(gene name synonym)|uniprotkb:Complexed with DOR1 protein 2(gene name synonym)|uniprotkb:Protein SEC37(gene name synonym) psi-mi:cog3_yeast(display_long)|uniprotkb:COG3(gene name)|psi-mi:COG3(display_short)|uniprotkb:GRD20(gene name synonym)|uniprotkb:SEC34(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 3(gene name synonym)|uniprotkb:Protein SEC34(gene name synonym)|uniprotkb:YER157W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338813|imex:IM-14275-2262 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014357.1|sgd:S000004986|dip:DIP-4373N|mint:P53959|ensemblfungi:YNL041C(gene)|ensemblfungi:YNL041C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|interpro:IPR010490(Conserved oligomeric complex COG6) ensemblfungi:YER157W(gene)|ensemblfungi:YER157W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR007265(Sec34-like protein)|refseq:NP_011084.1|sgd:S000000959|dip:DIP-4728N|mint:P40094 psi-mi:"MI:0469"(intact) - crc64:C7AFBE99010FE571 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:PF6acMk/xEQAGjElIukh7JGI46Y559292 rogid:R2r0ZW+nxrykdTHq1cJy9zOmvHo559292 intact-crc:FE6A8497DCF93886|rigid:9JrF9cqWTF9qxsvatj51ncBA3cw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38328 uniprotkb:P53974 intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C intact:EBI-9817|ensemblfungi:YNL020C|uniprotkb:D6W1F9 psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:ark1_yeast(display_long)|uniprotkb:N2823(orf name)|uniprotkb:YNL020C(locus name)|uniprotkb:ARK1(gene name)|psi-mi:ARK1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338824|imex:IM-14275-2263 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 refseq:NP_014378.1|sgd:S000004965|ensemblfungi:YNL020C(gene)|ensemblfungi:YNL020C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:2RPN|reactome:R-SCE-8856828|dip:DIP-4381N|mint:P53974 psi-mi:"MI:0469"(intact) crc64:D75C6BB8EC35EEDF crc64:139CA4CA1B6A181F figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 rogid:0Hk0FS0JZhF87+YeYCya2eAyH8M559292 intact-crc:1418BBDD1C3E0296|rigid:umXIbxbrP0I8nL7Ve7NlSBU6Duw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54113 uniprotkb:P23542 intact:EBI-14213|uniprotkb:E9PAG6|ensemblfungi:YLR028C|uniprotkb:D6VY30 intact:EBI-2002|uniprotkb:D6VY29|ensemblfungi:YLR027C psi-mi:pur91_yeast(display_long)|uniprotkb:ADE16(gene name)|psi-mi:ADE16(display_short)|uniprotkb:YLR028C(locus name) psi-mi:aatc_yeast(display_long)|uniprotkb:AAT2(gene name)|psi-mi:AAT2(display_short)|uniprotkb:YLR027C(locus name)|uniprotkb:ASP5(gene name synonym)|uniprotkb:L1746(orf name)|uniprotkb:Transaminase A(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338835|imex:IM-14275-2264 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P54113|refseq:NP_013128.1|sgd:S000004018|ensemblfungi:YLR028C(gene)|ensemblfungi:YLR028C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|interpro:IPR036914|dip:DIP-4657N refseq:NP_013127.2|sgd:S000004017|dip:DIP-2897N|mint:P23542|go:"GO:0019266"(asparagine biosynthetic process from oxaloacetate)|go:"GO:0030170"(pyridoxal phosphate binding)|interpro:IPR000796(Aspartate/other aminotransferase)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:1YAA|reactome:R-SCE-70263|reactome:R-SCE-8963693|ensemblfungi:YLR027C(gene)|ensemblfungi:YLR027C_mRNA(transcript)|go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0006532"(aspartate biosynthetic process)|go:"GO:0006536"(glutamate metabolic process) psi-mi:"MI:0469"(intact) - crc64:D25F40F6C6DD2B33 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SbZvY+c2tg098pE/sezKQp+3cFE559292 rogid:eNypS723YWwMMuWVVoTnidvQuaA559292 intact-crc:2028B64BAC843D5E|rigid:b51+Y1Gn7muUOA2xbZ6O6X0eOi8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32610 uniprotkb:P54113 intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W intact:EBI-14213|uniprotkb:E9PAG6|ensemblfungi:YLR028C|uniprotkb:D6VY30 psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym) psi-mi:pur91_yeast(display_long)|uniprotkb:ADE16(gene name)|psi-mi:ADE16(display_short)|uniprotkb:YLR028C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338846|imex:IM-14275-2265 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610 mint:P54113|refseq:NP_013128.1|sgd:S000004018|ensemblfungi:YLR028C(gene)|ensemblfungi:YLR028C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|interpro:IPR036914|dip:DIP-4657N psi-mi:"MI:0469"(intact) crc64:FDE93E1FAF0AEC5B - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292 rogid:SbZvY+c2tg098pE/sezKQp+3cFE559292 intact-crc:11BEB61CA1325110|rigid:vHQ6Mzj+JxDKmJU2atFznGZht/M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38009 uniprotkb:P54113 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 intact:EBI-14213|uniprotkb:E9PAG6|ensemblfungi:YLR028C|uniprotkb:D6VY30 psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:pur91_yeast(display_long)|uniprotkb:ADE16(gene name)|psi-mi:ADE16(display_short)|uniprotkb:YLR028C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338857|imex:IM-14275-2266 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N mint:P54113|refseq:NP_013128.1|sgd:S000004018|ensemblfungi:YLR028C(gene)|ensemblfungi:YLR028C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|interpro:IPR036914|dip:DIP-4657N psi-mi:"MI:0469"(intact) crc64:8ABA71761B512242 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 rogid:SbZvY+c2tg098pE/sezKQp+3cFE559292 intact-crc:25B7E727F321D15E|rigid:4p+2fbkcYZWPnZ/Hz+TVa+/s+Xw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54113 uniprotkb:P54113 intact:EBI-14213|uniprotkb:E9PAG6|ensemblfungi:YLR028C|uniprotkb:D6VY30 intact:EBI-14213|uniprotkb:E9PAG6|ensemblfungi:YLR028C|uniprotkb:D6VY30 psi-mi:pur91_yeast(display_long)|uniprotkb:ADE16(gene name)|psi-mi:ADE16(display_short)|uniprotkb:YLR028C(locus name) psi-mi:pur91_yeast(display_long)|uniprotkb:ADE16(gene name)|psi-mi:ADE16(display_short)|uniprotkb:YLR028C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338868|imex:IM-14275-2267 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P54113|refseq:NP_013128.1|sgd:S000004018|ensemblfungi:YLR028C(gene)|ensemblfungi:YLR028C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|interpro:IPR036914|dip:DIP-4657N mint:P54113|refseq:NP_013128.1|sgd:S000004018|ensemblfungi:YLR028C(gene)|ensemblfungi:YLR028C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|interpro:IPR036914|dip:DIP-4657N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SbZvY+c2tg098pE/sezKQp+3cFE559292 rogid:SbZvY+c2tg098pE/sezKQp+3cFE559292 intact-crc:E678BCDC3ECAE4A0|rigid:fj/ApC3gYy+TIZU5EZycy1vzWiQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00816 uniprotkb:P54113 intact:EBI-8270|uniprotkb:D6VS13|ensemblfungi:YDR028C intact:EBI-14213|uniprotkb:E9PAG6|ensemblfungi:YLR028C|uniprotkb:D6VY30 psi-mi:reg1_yeast(display_long)|uniprotkb:PZF240(gene name synonym)|uniprotkb:SPP43(gene name synonym)|uniprotkb:SRN1(gene name synonym)|uniprotkb:YD9813.06C(orf name)|uniprotkb:YDR028C(locus name)|uniprotkb:REG1(gene name)|psi-mi:REG1(display_short)|uniprotkb:HEX2(gene name synonym)|uniprotkb:Protein HEX2(gene name synonym)|uniprotkb:Second-site suppressor of the rna1-1 mutation 1(gene name synonym) psi-mi:pur91_yeast(display_long)|uniprotkb:ADE16(gene name)|psi-mi:ADE16(display_short)|uniprotkb:YLR028C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338879|imex:IM-14275-2268 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010311.1|sgd:S000002435|dip:DIP-2513N|mint:Q00816|ensemblfungi:YDR028C(gene)|ensemblfungi:YDR028C_mRNA(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005773"(vacuole)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007039"(protein catabolic process in the vacuole)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|interpro:IPR013860(Protein of unknown function DUF1752, fungi) mint:P54113|refseq:NP_013128.1|sgd:S000004018|ensemblfungi:YLR028C(gene)|ensemblfungi:YLR028C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|interpro:IPR036914|dip:DIP-4657N psi-mi:"MI:0469"(intact) crc64:0D4AAC75E111B346 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1ozfVSXyn7y5fR411wXk3gX8EfU559292 rogid:SbZvY+c2tg098pE/sezKQp+3cFE559292 intact-crc:59C3D1C64AD6CFD3|rigid:reFZK+k+n9i+Vfq2uLO3QYGq/yw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54781 uniprotkb:P08964 intact:EBI-6563|uniprotkb:D6VZI9|uniprotkb:E9P965|ensemblfungi:YMR015C intact:EBI-11650|ensemblfungi:YHR023W|uniprotkb:D3DKX0 psi-mi:erg5_yeast(display_long)|uniprotkb:ERG5(gene name)|psi-mi:ERG5(display_short)|uniprotkb:CYP61(gene name synonym)|uniprotkb:YMR015C(locus name)|uniprotkb:YM9711.02C(orf name)|uniprotkb:C-22 sterol desaturase(gene name synonym) psi-mi:myo1_yeast(display_long)|uniprotkb:MYO1(gene name)|psi-mi:MYO1(display_short)|uniprotkb:Type II myosin(gene name synonym)|uniprotkb:YHR023W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338890|imex:IM-14275-2269 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013728.1|sgd:S000004617|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR036396|mint:P54781|ensemblfungi:YMR015C(gene)|ensemblfungi:YMR015C_mRNA(transcript)|go:"GO:0000249"(C-22 sterol desaturase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding) ensemblfungi:YHR023W(gene)|ensemblfungi:YHR023W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016460"(myosin II complex)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032033"(myosin II light chain binding)|go:"GO:1902404"(mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1904498"(protein localization to mitotic actomyosin contractile ring)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036961|reactome:R-SCE-5627123|refseq:NP_011888.1|sgd:S000001065|mint:P08964|dip:DIP-808N psi-mi:"MI:0469"(intact) - crc64:6F54C7611F43DC9F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ScwspGheTequLP3AGjoNZM3cp3E559292 rogid:Itn/sUB37QxWeXWSpQufNogGAHY559292 intact-crc:95942BAD8EEA9FD1|rigid:fsBJR2IeeIO/c2zqtWTSKLZ3rNk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54781 uniprotkb:P10614 intact:EBI-6563|uniprotkb:D6VZI9|uniprotkb:E9P965|ensemblfungi:YMR015C intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:erg5_yeast(display_long)|uniprotkb:ERG5(gene name)|psi-mi:ERG5(display_short)|uniprotkb:CYP61(gene name synonym)|uniprotkb:YMR015C(locus name)|uniprotkb:YM9711.02C(orf name)|uniprotkb:C-22 sterol desaturase(gene name synonym) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338901|imex:IM-14275-2270 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013728.1|sgd:S000004617|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR036396|mint:P54781|ensemblfungi:YMR015C(gene)|ensemblfungi:YMR015C_mRNA(transcript)|go:"GO:0000249"(C-22 sterol desaturase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ScwspGheTequLP3AGjoNZM3cp3E559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:660E814AF0E20F57|rigid:LoXzRVbpui5CxiF8eT/XJAq1sfQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20434 uniprotkb:P54781 intact:EBI-15781|uniprotkb:Q02121|ensemblfungi:YBR154C|uniprotkb:D6VQE9 intact:EBI-6563|uniprotkb:D6VZI9|uniprotkb:E9P965|ensemblfungi:YMR015C psi-mi:rpab1_yeast(display_long)|uniprotkb:RPB5(gene name)|psi-mi:RPB5(display_short)|uniprotkb:YBR154C(locus name)|uniprotkb:YBR1204(orf name)|uniprotkb:RPA7(gene name synonym)|uniprotkb:RPC9(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide(gene name synonym)|uniprotkb:ABC27(gene name synonym) psi-mi:erg5_yeast(display_long)|uniprotkb:ERG5(gene name)|psi-mi:ERG5(display_short)|uniprotkb:CYP61(gene name synonym)|uniprotkb:YMR015C(locus name)|uniprotkb:YM9711.02C(orf name)|uniprotkb:C-22 sterol desaturase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338912|imex:IM-14275-2271 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|rcsb pdb:1WCM|rcsb pdb:1Y1V|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|rcsb pdb:2B63|rcsb pdb:2B8K|interpro:IPR020608|interpro:IPR020609|rcsb pdb:2E2H|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:1DZF|rcsb pdb:1I3Q|rcsb pdb:2E2I|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:5M5Y|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6H67|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:2E2J|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|ensemblfungi:YBR154C(gene)|ensemblfungi:YBR154C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4V1M|rcsb pdb:2JA5|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2JA6|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:2JA7|rcsb pdb:3GTG|rcsb pdb:2JA8|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:2NVQ|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4YM7|rcsb pdb:5C3E|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5G5L|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6H68|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|rcsb pdb:6UQ2|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-77075|reactome:R-SCE-9018519|refseq:NP_009712.1|sgd:S000000358|dip:DIP-71N|mint:P20434 refseq:NP_013728.1|sgd:S000004617|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR036396|mint:P54781|ensemblfungi:YMR015C(gene)|ensemblfungi:YMR015C_mRNA(transcript)|go:"GO:0000249"(C-22 sterol desaturase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding) psi-mi:"MI:0469"(intact) crc64:2A15F7114D69D829 - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:j/jAJ2fXWf4ebK1aWTWrKERGUpM559292 rogid:ScwspGheTequLP3AGjoNZM3cp3E559292 intact-crc:25D445DB52B18699|rigid:7ki671So+NOTCZwGDpSn7SvntKM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54781 uniprotkb:P21147 intact:EBI-6563|uniprotkb:D6VZI9|uniprotkb:E9P965|ensemblfungi:YMR015C intact:EBI-2098|ensemblfungi:YGL055W|uniprotkb:D6VU86|uniprotkb:E9P911 psi-mi:erg5_yeast(display_long)|uniprotkb:ERG5(gene name)|psi-mi:ERG5(display_short)|uniprotkb:CYP61(gene name synonym)|uniprotkb:YMR015C(locus name)|uniprotkb:YM9711.02C(orf name)|uniprotkb:C-22 sterol desaturase(gene name synonym) psi-mi:aco1_yeast(display_long)|uniprotkb:OLE1(gene name)|psi-mi:OLE1(display_short)|uniprotkb:Stearoyl-CoA desaturase 1(gene name synonym)|uniprotkb:Fatty acid desaturase 1(gene name synonym)|uniprotkb:YGL055W(locus name)|uniprotkb:Delta 9 fatty acid desaturase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338923|imex:IM-14275-2272 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013728.1|sgd:S000004617|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR036396|mint:P54781|ensemblfungi:YMR015C(gene)|ensemblfungi:YMR015C_mRNA(transcript)|go:"GO:0000249"(C-22 sterol desaturase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding) ensemblfungi:YGL055W(gene)|ensemblfungi:YGL055W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0004768"(stearoyl-CoA 9-desaturase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|sgd:S000003023|refseq:NP_011460.3|dip:DIP-5026N|mint:P21147|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR001522(Fatty acid desaturase, type 1, C-terminal)|interpro:IPR005804(Fatty acid desaturase, type 1)|interpro:IPR009160(Delta-9 acyl-CoA desaturase with haem/steroid binding region)|interpro:IPR015876(Fatty acid desaturase, type 1, core)|interpro:IPR018506|interpro:IPR036400 psi-mi:"MI:0469"(intact) - crc64:A6CC78DD4210ECCA figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ScwspGheTequLP3AGjoNZM3cp3E559292 rogid:Ibp4I76IX/sMf5kLO05pTBZ3TNE559292 intact-crc:425C2E07838F0EB4|rigid:l6oJIT/aovHKW0+0gxmuCiQQNPA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:P54781 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-6563|uniprotkb:D6VZI9|uniprotkb:E9P965|ensemblfungi:YMR015C psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:erg5_yeast(display_long)|uniprotkb:ERG5(gene name)|psi-mi:ERG5(display_short)|uniprotkb:CYP61(gene name synonym)|uniprotkb:YMR015C(locus name)|uniprotkb:YM9711.02C(orf name)|uniprotkb:C-22 sterol desaturase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338934|imex:IM-14275-2273 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_013728.1|sgd:S000004617|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR036396|mint:P54781|ensemblfungi:YMR015C(gene)|ensemblfungi:YMR015C_mRNA(transcript)|go:"GO:0000249"(C-22 sterol desaturase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:ScwspGheTequLP3AGjoNZM3cp3E559292 intact-crc:4FF2062AECF975D2|rigid:fz9v5p6PPwnQSKE7osStmwcKWpg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:P54781 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-6563|uniprotkb:D6VZI9|uniprotkb:E9P965|ensemblfungi:YMR015C psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:erg5_yeast(display_long)|uniprotkb:ERG5(gene name)|psi-mi:ERG5(display_short)|uniprotkb:CYP61(gene name synonym)|uniprotkb:YMR015C(locus name)|uniprotkb:YM9711.02C(orf name)|uniprotkb:C-22 sterol desaturase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338945|imex:IM-14275-2274 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_013728.1|sgd:S000004617|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR036396|mint:P54781|ensemblfungi:YMR015C(gene)|ensemblfungi:YMR015C_mRNA(transcript)|go:"GO:0000249"(C-22 sterol desaturase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:ScwspGheTequLP3AGjoNZM3cp3E559292 intact-crc:5566916246EC8264|rigid:gVVZ0YaBvTYU0ORCqh6ZG9jSilk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12226 uniprotkb:P54781 intact:EBI-2057459|uniprotkb:D6VXU6|ensemblfungi:YLL063C intact:EBI-6563|uniprotkb:D6VZI9|uniprotkb:E9P965|ensemblfungi:YMR015C psi-mi:ayt1_yeast(display_long)|uniprotkb:L0549(orf name)|uniprotkb:YLL063C(locus name)|uniprotkb:AYT1(gene name)|psi-mi:AYT1(display_short) psi-mi:erg5_yeast(display_long)|uniprotkb:ERG5(gene name)|psi-mi:ERG5(display_short)|uniprotkb:CYP61(gene name synonym)|uniprotkb:YMR015C(locus name)|uniprotkb:YM9711.02C(orf name)|uniprotkb:C-22 sterol desaturase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338956|imex:IM-14275-2275 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013037.1|sgd:S000003986|interpro:IPR003480(Transferase)|interpro:IPR023213|mint:Q12226|ensemblfungi:YLL063C(gene)|ensemblfungi:YLL063C_mRNA(transcript)|go:"GO:0016747"(acyltransferase activity, transferring groups other than amino-acyl groups)|go:"GO:0043387"(mycotoxin catabolic process)|go:"GO:0045462"(trichothecene 3-O-acetyltransferase activity) refseq:NP_013728.1|sgd:S000004617|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR036396|mint:P54781|ensemblfungi:YMR015C(gene)|ensemblfungi:YMR015C_mRNA(transcript)|go:"GO:0000249"(C-22 sterol desaturase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GOn06WxIqTkEPbFcgiGk96Uju0k559292 rogid:ScwspGheTequLP3AGjoNZM3cp3E559292 intact-crc:1090038619D4FADD|rigid:Sjwk6vAGb0g70MhfyKn206tIn8E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C268 uniprotkb:P54783 intact:EBI-2044092|uniprotkb:D6VPV9|ensemblfungi:YBL039W-B intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:yb39b_yeast(display_long)|uniprotkb:YBL039W-B(locus name) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338967|imex:IM-14275-2276 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000028517|refseq:NP_878045.1|mint:P0C268|ensemblfungi:YBL039W-B(gene)|ensemblfungi:YBL039W-B_mRNA(transcript)|go:"GO:0005777"(peroxisome) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:EfowKSHyZ6Fgw3vWQ74mzPwXTbQ559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:BB0DF22DDB01E083|rigid:v0LXMKteZ/IHkaXRh2GH28YFyPc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:P54783 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338978|imex:IM-14275-2277 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:03A73E6EDA6D1D83|rigid:xrWLAk3n68VxUYiZhjz1lMfNqDs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54783 uniprotkb:P18411 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 intact:EBI-20609|uniprotkb:D6VPL0|ensemblfungi:YAL008W psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:fun14_yeast(display_long)|uniprotkb:FUN14(gene name)|psi-mi:FUN14(display_short)|uniprotkb:YAL008W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6338989|imex:IM-14275-2278 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 go:"GO:0007005"(mitochondrion organization)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0055091"(phospholipid homeostasis)|reactome:R-SCE-8934903|sgd:S000000006|interpro:IPR007014(FUN14)|refseq:NP_009394.1|ensemblfungi:YAL008W_mRNA(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|ensemblfungi:YAL008W(gene)|mint:P18411 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 rogid:OzV8V+XMS7qJmUtXubBZUVCgya0559292 intact-crc:7E552E18F39C15AC|rigid:0qZcTwo8ane+KJiADDytdQDx6ts false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54783 uniprotkb:P22289 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 intact:EBI-19947|uniprotkb:D6VUW6|ensemblfungi:YGR183C psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:qcr9_yeast(display_long)|uniprotkb:QCR9(gene name)|psi-mi:QCR9(display_short)|uniprotkb:Ubiquinol-cytochrome c oxidoreductase subunit 9(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c reductase 7.3 kDa protein(gene name synonym)|uniprotkb:YGR183C(locus name)|uniprotkb:Cytochrome c1 non-heme 7.3 kDa protein(gene name synonym)|uniprotkb:Complex III subunit X(gene name synonym)|uniprotkb:Complex III subunit 9(gene name synonym)|uniprotkb:UCR9(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339000|imex:IM-14275-2279 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 interpro:IPR036656|refseq:NP_011699.1|sgd:S000003415|interpro:IPR008027(Ubiquinol-cytochrome C reductase, UQCRX/QCR9-like)|ensemblfungi:YGR183C(gene)|ensemblfungi:YGR183C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0009060"(aerobic respiration)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:1902600"(proton transmembrane transport)|rcsb pdb:1EZV|rcsb pdb:1KB9|rcsb pdb:1KYO|rcsb pdb:1P84|rcsb pdb:2IBZ|rcsb pdb:3CX5|rcsb pdb:3CXH|rcsb pdb:4PD4|rcsb pdb:6GIQ|rcsb pdb:6HU9|rcsb pdb:6T0B|rcsb pdb:6T15|reactome:R-SCE-611105|mint:P22289 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 rogid:C2Sa3lOqiMzEpx/H0AdOUS3mEYk559292 intact-crc:E093CEC69A1DC16F|rigid:+pRjHTYMUgvbpOoilD/2CzDzSb0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35180 uniprotkb:P54783 intact:EBI-12522|uniprotkb:D6VUL4|ensemblfungi:YGR082W intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:tom20_yeast(display_long)|uniprotkb:MOM19(gene name synonym)|uniprotkb:YGR082W(locus name)|uniprotkb:TOM20(gene name)|psi-mi:TOM20(display_short)|uniprotkb:MAS20(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 20 kDa subunit(gene name synonym)|uniprotkb:Protein MAS20(gene name synonym) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339011|imex:IM-14275-2280 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR082W(gene)|ensemblfungi:YGR082W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR023392|refseq:NP_011596.1|sgd:S000003314|dip:DIP-2539N|mint:P35180 go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:7U00YLVWcaegWlJEKzGblv6STx4559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:A4E71F2FADA54381|rigid:Ddu26nV5X8fUXhvZrOhZwWmMdqM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54783 uniprotkb:P35844 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 intact:EBI-9648|ensemblfungi:YPL145C|uniprotkb:D6W3M4|uniprotkb:E9P8U8 psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:kes1_yeast(display_long)|uniprotkb:KES1(gene name)|psi-mi:KES1(display_short)|uniprotkb:OSH4(gene name synonym)|uniprotkb:Protein KES1(gene name synonym)|uniprotkb:LPI3C(orf name)|uniprotkb:P2614(orf name)|uniprotkb:YPL145C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339022|imex:IM-14275-2281 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 ensemblfungi:YPL145C(gene)|ensemblfungi:YPL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035621"(ER to Golgi ceramide transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|rcsb pdb:1ZHT|rcsb pdb:1ZHW|rcsb pdb:1ZHX|rcsb pdb:1ZHY|rcsb pdb:1ZHZ|rcsb pdb:1ZI7|rcsb pdb:3SPW|rcsb pdb:4F4B|rcsb pdb:4FES|rcsb pdb:4JCH|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_015180.1|sgd:S000006066|dip:DIP-2867N|mint:P35844 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 rogid:6vsHrA4RScGr2+xmii0wiuvK1OM559292 intact-crc:CFFB655D6F7C5E9F|rigid:xrb/8iB2DMQPfzn/y3fGmgKmt1w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38009 uniprotkb:P54783 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339033|imex:IM-14275-2282 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) crc64:8ABA71761B512242 - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:0DF3E533DEFF5BCB|rigid:PznQZZxaBwdhUqJvkw8Avp0+Or8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38295 uniprotkb:P54783 intact:EBI-20890|uniprotkb:D6VQH2|ensemblfungi:YBR177C intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:mcfs2_yeast(display_long)|uniprotkb:YBR177C(locus name)|uniprotkb:YBR1239(orf name)|uniprotkb:EHT1(gene name)|psi-mi:EHT1(display_short)|uniprotkb:Alcohol O-acetyltransferase(gene name synonym)|uniprotkb:Ethanol hexanoyl transferase 1(gene name synonym) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339044|imex:IM-14275-2283 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009736.3|sgd:S000000381|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|mint:P38295|interpro:IPR029058|ensemblfungi:YBR177C(gene)|ensemblfungi:YBR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034319"(alcohol O-butanoyltransferase activity)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|reactome:R-SCE-1483191 go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9arzlcrZmkK0VXN7Zw87dAe1Txc559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:584595D4E18A377A|rigid:maumHpxnwXcEuJuirx7f7LoGn50 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38756 uniprotkb:P54783 intact:EBI-24431|uniprotkb:D3DKU6|ensemblfungi:YHR003C intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:tcd1_yeast(display_long)|uniprotkb:TCD1(gene name)|psi-mi:TCD1(display_short)|uniprotkb:"t(6)A37 dehydratase 1"(gene name synonym)|uniprotkb:YHR003C(locus name) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339055|imex:IM-14275-2284 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011866.1|sgd:S000001045|dip:DIP-4417N|mint:P38756|ensemblfungi:YHR003C(gene)|ensemblfungi:YHR003C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008641"(ubiquitin-like modifier activating enzyme activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0061503"(tRNA threonylcarbamoyladenosine dehydratase)|go:"GO:0061504"(cyclic threonylcarbamoyladenosine biosynthetic process)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR035985 go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Mce7jBtBDJ9bSrw+cQDCbhK8DvY559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:D89B70D91108FD80|rigid:zpRkMWEbVXATxy8isSU3tu+kCl4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54783 uniprotkb:P40582 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 intact:EBI-7941|uniprotkb:D6VVW9|ensemblfungi:YIR038C psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:gst1_yeast(display_long)|uniprotkb:YIR038C(locus name)|uniprotkb:GTT1(gene name)|psi-mi:GTT1(display_short)|uniprotkb:GST-I(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339066|imex:IM-14275-2285 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 refseq:NP_012304.1|sgd:S000001477|mint:P40582|dip:DIP-2103N|ensemblfungi:YIR038C(gene)|ensemblfungi:YIR038C_mRNA(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010731"(protein glutathionylation)|go:"GO:0071944"(cell periphery)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079 psi-mi:"MI:0469"(intact) - crc64:3C07D40D29F60DFF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 rogid:+bqzHpsoLw4j2qQBzHbkfldR5OU559292 intact-crc:196E314FF04490B4|rigid:H4jZ5L38JksEK8dcQ5r0o26CitQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54783 uniprotkb:P43497 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 intact:EBI-2044078|uniprotkb:D6VXJ1|ensemblfungi:YKL096W-A psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:cwp2_yeast(display_long)|uniprotkb:LPR1(gene name synonym)|uniprotkb:Low pH resistance protein 1(gene name synonym)|uniprotkb:YKL096BW(orf name)|uniprotkb:YKL444(orf name)|uniprotkb:YKL096W-A(locus name)|uniprotkb:CWP2(gene name)|psi-mi:CWP2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339077|imex:IM-14275-2286 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 refseq:NP_012826.1|sgd:S000001956|interpro:IPR000420(Yeast PIR protein repeat)|mint:P43497|ensemblfungi:YKL096W-A(gene)|ensemblfungi:YKL096W-A_mRNA(transcript)|go:"GO:0005199"(structural constituent of cell wall)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031505"(fungal-type cell wall organization) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 rogid:I1pf6N/8dUODvb5jhcXC902uuew559292 intact-crc:6BE2D32ABC62A0D8|rigid:iXh9HEZIAR/hJG2KQAgy8lyHMe0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54783 uniprotkb:P53206 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 intact:EBI-2044073|uniprotkb:D6VUE8|ensemblfungi:YGR012W psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:mcy1_yeast(display_long)|uniprotkb:MCY1(gene name)|psi-mi:MCY1(display_short)|uniprotkb:Cysteine synthase-like protein(gene name synonym)|uniprotkb:"O-acetylserine (thiol)-lyase"(gene name synonym)|uniprotkb:O-acetylserine sulfhydrylase(gene name synonym)|uniprotkb:YGR012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339088|imex:IM-14275-2287 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 refseq:NP_011526.1|sgd:S000003244|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|mint:P53206|interpro:IPR036052|ensemblfungi:YGR012W(gene)|ensemblfungi:YGR012W_mRNA(transcript)|go:"GO:0004124"(cysteine synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030170"(pyridoxal phosphate binding) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 rogid:7/zIKdpUok1wr1w3uUnMbL8mELw559292 intact-crc:9754D911415602D1|rigid:fhbqxRAoBR87vH4sH5jMNuORV00 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54783 uniprotkb:P54783 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339099|imex:IM-14275-2288 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:CC374A183259547A|rigid:FVulsh3GY3WOXbY/Myr/5OhaRYM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54783 uniprotkb:Q08926 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 intact:EBI-2044051|uniprotkb:D6W3I3|ensemblfungi:YPL186C psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:uip4_yeast(display_long)|uniprotkb:YPL186C(locus name)|uniprotkb:UIP4(gene name)|psi-mi:UIP4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339110|imex:IM-14275-2289 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 sgd:S000006107|refseq:NP_015138.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold)|mint:Q08926|ensemblfungi:YPL186C(gene)|ensemblfungi:YPL186C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 rogid:jZmXJYN6MQPlKDZXQnkU2tSI7vM559292 intact-crc:5A82899FC28AFDA5|rigid:w1iu7Gn322dGuazeX5AvMQVX1ds false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3E6R5 uniprotkb:P54783 intact:EBI-2044020|uniprotkb:D6VT15|ensemblfungi:YDR381C-A intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:yd381_yeast(display_long)|uniprotkb:YDR381C-A(locus name) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339121|imex:IM-14275-2290 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000007650|refseq:NP_219495.2|mint:Q3E6R5|ensemblfungi:YDR381C-A(gene)|ensemblfungi:YDR381C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0097250"(mitochondrial respirasome assembly) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mjm4bS1sHrB4mk74vy4eajY1DOs559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:C132A8E1EAE6A777|rigid:KtndvHMFcyoDRqE5haS8xuvWa3c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54783 uniprotkb:Q6Q5K6 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 intact:EBI-392766|ensemblfungi:YML058W-A|uniprotkb:D6VZB5 psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:hug1_yeast(display_long)|uniprotkb:HUG1(gene name)|psi-mi:HUG1(display_short)|uniprotkb:YML058W-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339132|imex:IM-14275-2291 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 ensemblfungi:YML058W-A(gene)|ensemblfungi:YML058W-A_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:1905117"(regulation of ribonucleoside-diphosphate reductase activity)|go:"GO:1990846"(ribonucleoside-diphosphate reductase inhibitor activity)|sgd:S000007472|refseq:NP_219498.1|mint:Q6Q5K6 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 rogid:x+quBrnP+8yql7JGQ1NK4j5ubbw559292 intact-crc:9D0B14E1B906E5A9|rigid:uI3f8QpXBE+EG26jO5xSIFv+PQc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54785 uniprotkb:P53551 intact:EBI-11160|uniprotkb:D6VZP4|ensemblfungi:YMR070W intact:EBI-8064|uniprotkb:Q6Q5R6|uniprotkb:D6W3P0|ensemblfungi:YPL127C psi-mi:mot3_yeast(display_long)|uniprotkb:MOT3(gene name)|psi-mi:MOT3(display_short)|uniprotkb:ROX7(gene name synonym)|uniprotkb:YMR070W(locus name)|uniprotkb:YM9916.09(orf name)|uniprotkb:Modulator of transcription protein 3(gene name synonym)|uniprotkb:Hypoxic gene repressor protein 7(gene name synonym) psi-mi:h1_yeast(display_long)|uniprotkb:HHO1(gene name)|psi-mi:HHO1(display_short)|uniprotkb:LPI17C(orf name)|uniprotkb:YPL127C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339143|imex:IM-14275-2292 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR070W(gene)|ensemblfungi:YMR070W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010895"(negative regulation of ergosterol biosynthetic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|refseq:NP_013786.1|sgd:S000004674|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:P54785|interpro:IPR036236 refseq:NP_015198.1|sgd:S000006048|mint:P53551|dip:DIP-6587N|ensemblfungi:YPL127C(gene)|ensemblfungi:YPL127C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0097100"(supercoiled DNA binding)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1UHM|rcsb pdb:1USS|rcsb pdb:1UST|rcsb pdb:1YQA psi-mi:"MI:0469"(intact) - crc64:B0C53AC186E49F96 figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Zdie8xxprTFGdCiDR7LWw5/XIEY559292 rogid:dPMYSAq1Cr7pfGGNgb3GDp3LnsQ559292 intact-crc:6BAD03AAB174A370|rigid:5XHeeEn6ae/Rg7GmvDU5CM/LiGY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54785 uniprotkb:P54785 intact:EBI-11160|uniprotkb:D6VZP4|ensemblfungi:YMR070W intact:EBI-11160|uniprotkb:D6VZP4|ensemblfungi:YMR070W psi-mi:mot3_yeast(display_long)|uniprotkb:MOT3(gene name)|psi-mi:MOT3(display_short)|uniprotkb:ROX7(gene name synonym)|uniprotkb:YMR070W(locus name)|uniprotkb:YM9916.09(orf name)|uniprotkb:Modulator of transcription protein 3(gene name synonym)|uniprotkb:Hypoxic gene repressor protein 7(gene name synonym) psi-mi:mot3_yeast(display_long)|uniprotkb:MOT3(gene name)|psi-mi:MOT3(display_short)|uniprotkb:ROX7(gene name synonym)|uniprotkb:YMR070W(locus name)|uniprotkb:YM9916.09(orf name)|uniprotkb:Modulator of transcription protein 3(gene name synonym)|uniprotkb:Hypoxic gene repressor protein 7(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339154|imex:IM-14275-2293 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR070W(gene)|ensemblfungi:YMR070W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010895"(negative regulation of ergosterol biosynthetic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|refseq:NP_013786.1|sgd:S000004674|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:P54785|interpro:IPR036236 ensemblfungi:YMR070W(gene)|ensemblfungi:YMR070W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010895"(negative regulation of ergosterol biosynthetic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|refseq:NP_013786.1|sgd:S000004674|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:P54785|interpro:IPR036236 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Zdie8xxprTFGdCiDR7LWw5/XIEY559292 rogid:Zdie8xxprTFGdCiDR7LWw5/XIEY559292 intact-crc:EBA214C760C5C00C|rigid:5JltEI14jRTkGVmzftHHjTOYzWQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06197 uniprotkb:P54837 intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339165|imex:IM-14275-2294 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:6E2E62252B3CB5E2 - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:2B8BE2F99C27EF31|rigid:TuUs++YX+2h0lzJNM71h9ZNdKZs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:P54837 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339176|imex:IM-14275-2295 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:68B9DB3D1F59A2D2|rigid:CvwyLcysts7uCBa7qdmhy/9LtNY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:P11076 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339187|imex:IM-14275-2296 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 psi-mi:"MI:0469"(intact) - crc64:796859026AC63CC0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 intact-crc:826272557E3E0CAF|rigid:f3kWRMmMHl631/kua0UaBr/oHhg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:P17898 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-2050738|uniprotkb:D6W152|ensemblfungi:YNL130C psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:cpt1_yeast(display_long)|uniprotkb:Diacylglycerol cholinephosphotransferase 1(gene name synonym)|uniprotkb:Sn-1,2-diacylglycerol cholinephosphotransferase(gene name synonym)|uniprotkb:N1218(orf name)|uniprotkb:N1867(orf name)|uniprotkb:YNL130C(locus name)|uniprotkb:CPT1(gene name)|psi-mi:CPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase CPT1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339198|imex:IM-14275-2297 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 sgd:S000005074|refseq:NP_014269.4|dip:DIP-7848N|mint:P17898|ensemblfungi:YNL130C(gene)|ensemblfungi:YNL130C_mRNA(transcript)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006657"(CDP-choline pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:PsU8UELFPsbtbzOS6oBnXJAuk/A559292 intact-crc:EF51192D24A6B6E3|rigid:8oJTduuy+iT3HLZl+BM6rWnzYTA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:P26570 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339209|imex:IM-14275-2298 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N psi-mi:"MI:0469"(intact) - crc64:8B7F009521F72C15 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 intact-crc:F00E1858523D0A83|rigid:sevZKDOAQ4zHX0aigjFVaFK0JhI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:P32915 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339220|imex:IM-14275-2299 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 intact-crc:B2CCC445601AEA43|rigid:tVkZwLB7jBJ5FFGcks93jZiKrKU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:P38084 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-3414|uniprotkb:D6VQ67|ensemblfungi:YBR068C psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:bap2_yeast(display_long)|uniprotkb:Branched-chain amino-acid permease 2(gene name synonym)|uniprotkb:BAP2(gene name)|psi-mi:BAP2(display_short)|uniprotkb:YBR068C(locus name)|uniprotkb:YBR0629(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339231|imex:IM-14275-2300 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 sgd:S000000272|refseq:NP_009624.4|dip:DIP-4910N|mint:P38084|ensemblfungi:YBR068C(gene)|ensemblfungi:YBR068C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015192"(L-phenylalanine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098713"(leucine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) psi-mi:"MI:0469"(intact) - crc64:B87FD6A7464E07F5 figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:7Fw7+M5mBikZBztHE2tSDpvBi/M559292 intact-crc:9A3DC93BFC14BD7F|rigid:XXgkKzIRJY7n0Jd0cEaUpRgBN8Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38142 uniprotkb:P54837 intact:EBI-21079|uniprotkb:D6VQN7|intact:EBI-2347460|uniprotkb:Q6B2Y5|ensemblfungi:YBR241C intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:yb91_yeast(display_long)|uniprotkb:YBR1625(orf name)|uniprotkb:YBR241C(locus name) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339242|imex:IM-14275-2301 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009800.1|sgd:S000000445|mint:P38142|dip:DIP-5363N|ensemblfungi:YBR241C(gene)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|reactome:R-SCE-189200|reactome:R-SCE-196836|reactome:R-SCE-422356|reactome:R-SCE-5653890|reactome:R-SCE-6798695|reactome:R-SCE-8981373|ensemblfungi:YBR241C_mRNA(transcript) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:B0qgnhfd17hrDGLrJ21KY/FCzTQ559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:445EA820441B7B29|rigid:S6uIpDNiSGZqrYDm8NiH/tsiysE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:P38264 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339253|imex:IM-14275-2302 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 intact-crc:7FAFD9EBC2791E1F|rigid:W2MpBygtSg3aKQ7nJ/QcL76EBJI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:P38353 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-18175|uniprotkb:D6VQS8|ensemblfungi:YBR283C psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:ssh1_yeast(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:Ssh1 complex subunit alpha(gene name synonym)|uniprotkb:Ssh1 complex subunit SSH1(gene name synonym)|uniprotkb:YBR2020(orf name)|uniprotkb:YBR283C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339264|imex:IM-14275-2303 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_009842.1|sgd:S000000487|ensemblfungi:YBR283C(gene)|ensemblfungi:YBR283C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:2WW9|rcsb pdb:2WWA|dip:DIP-4962N|mint:P38353 psi-mi:"MI:0469"(intact) - crc64:48267EEA3E0191BD figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:76wvZIdv7W5BQn6wI+sHOGQAyuc559292 intact-crc:07E3B8F4FDD6E000|rigid:duz489Hu82k6uWnZWKivEJLnIKA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:P38694 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-24511|uniprotkb:D3DKY6|ensemblfungi:YHR039C psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:msc7_yeast(display_long)|uniprotkb:MSC7(gene name)|psi-mi:MSC7(display_short)|uniprotkb:Meiotic sister-chromatid recombination protein 7(gene name synonym)|uniprotkb:YHR039C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339275|imex:IM-14275-2304 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_011904.1|sgd:S000001081|dip:DIP-1878N|mint:P38694|ensemblfungi:YHR039C(gene)|ensemblfungi:YHR039C_mRNA(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007131"(reciprocal meiotic recombination)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:p2xtb6/xYI/jfPNtO6JRZs+5t6I559292 intact-crc:833D5DEBF8B24BF2|rigid:t5Nn+evt+mtv/nhN19G8d0kE1DM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38819 uniprotkb:P54837 intact:EBI-6603|uniprotkb:D3DL60|ensemblfungi:YHR110W intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:erp5_yeast(display_long)|uniprotkb:ERP5(gene name)|psi-mi:ERP5(display_short)|uniprotkb:YHR110W(locus name) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339286|imex:IM-14275-2305 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011978.1|sgd:S000001152|mint:P38819|dip:DIP-7586N|ensemblfungi:YHR110W(gene)|ensemblfungi:YHR110W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dxo+Sd/z45fHXllQ80yOOxm19jE559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:542D16787614D8B3|rigid:R0NDwtkzeLK3HIvu2ueSVWIRtIc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38992 uniprotkb:P54837 intact:EBI-18574|ensemblfungi:YDR297W|uniprotkb:D6VSS6 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:sur2_yeast(display_long)|uniprotkb:SUR2(gene name)|psi-mi:SUR2(display_short)|uniprotkb:SYR2(gene name synonym)|uniprotkb:YDR297W(locus name)|uniprotkb:D9740.8(orf name)|uniprotkb:Syringomycin response protein 2(gene name synonym) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339297|imex:IM-14275-2306 author score:93.51 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0042284"(sphingolipid delta-4 desaturase activity)|interpro:IPR006694(Fatty acid hydroxylase)|go:"GO:0006665"(sphingolipid metabolic process)|ensemblfungi:YDR297W(gene)|ensemblfungi:YDR297W_mRNA(transcript)|go:"GO:0000170"(sphingosine hydroxylase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|refseq:NP_010583.1|sgd:S000002705|dip:DIP-7741N|mint:P38992 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:93.51|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HcXW6Nko6+g+16d/ehjh8p2sl8Y559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:8ACBC580797DC3DE|rigid:fNkijGQ7sWOWuXTXleHXl/wNLSg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:P40350 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-2470|uniprotkb:D6W3E3|ensemblfungi:YPL227C psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:alg5_yeast(display_long)|uniprotkb:ALG5(gene name)|psi-mi:ALG5(display_short)|uniprotkb:YPL227C(locus name)|uniprotkb:P1437(orf name)|uniprotkb:Asparagine-linked glycosylation protein 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339308|imex:IM-14275-2307 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_015097.1|sgd:S000006148|dip:DIP-5651N|mint:P40350|ensemblfungi:YPL227C(gene)|ensemblfungi:YPL227C_mRNA(transcript)|go:"GO:0004581"(dolichyl-phosphate beta-glucosyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR035518|reactome:R-SCE-480985 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:aKi97cbwqo7kNWhtRyzG3UOLH4U559292 intact-crc:9522481D1D5C6D32|rigid:DKFhTSwkKssi/EUamhxg1UnfcBM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:P40540 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339319|imex:IM-14275-2308 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) - crc64:6DBEEEE7722203B0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 intact-crc:8C277D7D19FA9BBF|rigid:VdHs4y3YIjFa/d34GxTP4jKQXUQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40582 uniprotkb:P54837 intact:EBI-7941|uniprotkb:D6VVW9|ensemblfungi:YIR038C intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:gst1_yeast(display_long)|uniprotkb:YIR038C(locus name)|uniprotkb:GTT1(gene name)|psi-mi:GTT1(display_short)|uniprotkb:GST-I(gene name synonym) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339330|imex:IM-14275-2309 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012304.1|sgd:S000001477|mint:P40582|dip:DIP-2103N|ensemblfungi:YIR038C(gene)|ensemblfungi:YIR038C_mRNA(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010731"(protein glutathionylation)|go:"GO:0071944"(cell periphery)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:3C07D40D29F60DFF - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+bqzHpsoLw4j2qQBzHbkfldR5OU559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:98AB7D7454178198|rigid:DiHkQtxlOFAPMSi0QY+GTbMHkRU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:P41806 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-20323|uniprotkb:D6VUN7|uniprotkb:Q6Q5Q3|ensemblfungi:YGR105W psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:vma21_yeast(display_long)|uniprotkb:VMA21(gene name)|psi-mi:VMA21(display_short)|uniprotkb:YGR105W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339341|imex:IM-14275-2310 author score:99.37 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 sgd:S000003337|refseq:NP_011619.3|ensemblfungi:YGR105W(gene)|ensemblfungi:YGR105W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|interpro:IPR019013|dip:DIP-5526N|mint:P41806 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.37|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:Ailhh4PtjuOy5Jiwx8aN7cHFddk559292 intact-crc:E8706DD784298BBC|rigid:rZF+NoKZFfWC5KNPhbq8yLC2ql8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:P53198 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-2058104|uniprotkb:D6VUD6|uniprotkb:E9P916|ensemblfungi:YGL002W psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:erp6_yeast(display_long)|uniprotkb:ERP6(gene name)|psi-mi:ERP6(display_short)|uniprotkb:YGL002W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339352|imex:IM-14275-2311 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_011513.1|sgd:S000002970|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:P53198|ensemblfungi:YGL002W(gene)|ensemblfungi:YGL002W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:pM23btPgVfhIqmxeV0jxQGSX4/8559292 intact-crc:8FC93614A087F2B1|rigid:EhiB05hecFWey8tfZ9/ahAgJEQI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:P53337 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339363|imex:IM-14275-2312 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 intact-crc:68DDF42E55BFBC6E|rigid:93TNdlDFpZ91mQa/dG38B3Vh6oo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:P54837 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339374|imex:IM-14275-2313 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:ECAE29314BFABB94|rigid:Kg09Ifmdeo5XuQ3CIcQRF5tsxnI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02774 uniprotkb:P54837 intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339385|imex:IM-14275-2314 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:3B64F9FA338A1416|rigid:8avC5Qth/8dOVkS5225EfJAphj8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:Q02896 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-22203|uniprotkb:D6W3T0|ensemblfungi:YPL087W psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:ydc1_yeast(display_long)|uniprotkb:YDC1(gene name)|psi-mi:YDC1(display_short)|uniprotkb:Acyl-CoA-independent ceramide synthase(gene name synonym)|uniprotkb:LPG21W(orf name)|uniprotkb:YPL087W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339396|imex:IM-14275-2315 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_015238.1|sgd:S000006008|dip:DIP-7600N|mint:Q02896|ensemblfungi:YPL087W(gene)|ensemblfungi:YPL087W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046514"(ceramide catabolic process)|go:"GO:0070774"(phytoceramidase activity)|go:"GO:0071633"(dihydroceramidase activity)|interpro:IPR008901(Alkaline phytoceramidase)|reactome:R-SCE-1660661 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:UjLo2FMUWJPaHBDIYPjWZbqpk98559292 intact-crc:9F11A152F552E5E7|rigid:C/JyWI+xbflykhQJwNieRJkKfPI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:P54837 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339407|imex:IM-14275-2316 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:F6373D19E1EF4C22|rigid:V5KQkDduN7O4IuduxAjK7NTdcJI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:Q06144 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339418|imex:IM-14275-2317 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:2F474503CAB7C195 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 intact-crc:B59EB60F871C4C5A|rigid:acmKM3DLPIUB/Ye44UerHPDleT8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08926 uniprotkb:P54837 intact:EBI-2044051|uniprotkb:D6W3I3|ensemblfungi:YPL186C intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:uip4_yeast(display_long)|uniprotkb:YPL186C(locus name)|uniprotkb:UIP4(gene name)|psi-mi:UIP4(display_short) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339429|imex:IM-14275-2318 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006107|refseq:NP_015138.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold)|mint:Q08926|ensemblfungi:YPL186C(gene)|ensemblfungi:YPL186C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jZmXJYN6MQPlKDZXQnkU2tSI7vM559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:FBD325ED1F7A0367|rigid:xvytDIWY1Y/NjF/R+OrWWBZ9e3Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:P54837 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339440|imex:IM-14275-2319 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:967999BEDC5CD446|rigid:1JiGo0IfUFI26ISdQZI4Q/Gdr8Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:Q12450 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-6598|uniprotkb:D6W282|ensemblfungi:YOR016C psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:erp4_yeast(display_long)|uniprotkb:ERP4(gene name)|psi-mi:ERP4(display_short)|uniprotkb:YOR016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339451|imex:IM-14275-2320 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_014659.1|sgd:S000005542|mint:Q12450|dip:DIP-7868N|ensemblfungi:YOR016C(gene)|ensemblfungi:YOR016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:An7as6LjEDUYrLvEbua3xSL6bEk559292 intact-crc:C723F8EEAAC3E0C3|rigid:ebfCwQmyJucHNsGqydaflWWbVE4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99287 uniprotkb:P54837 intact:EBI-37523|uniprotkb:D6W2M3|ensemblfungi:YOR165W intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:sey1_yeast(display_long)|uniprotkb:SEY1(gene name)|psi-mi:SEY1(display_short)|uniprotkb:YOR165W(locus name)|uniprotkb:Synthetic enhancer of YOP1 protein(gene name synonym)|uniprotkb:O3590(orf name) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339462|imex:IM-14275-2321 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014808.1|sgd:S000005691|dip:DIP-49373N|mint:Q99287|ensemblfungi:YOR165W(gene)|ensemblfungi:YOR165W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0061024"(membrane organization)|go:"GO:0071944"(cell periphery)|interpro:IPR008803(Root hair defective 3 GTP-binding)|interpro:IPR027417|interpro:IPR030386 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:DEC0C9EC3AB172DF - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zFsgalfyUvAuuV51vChJjraiQmI559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:E6711E6318CB22F1|rigid:0QHJiqBB5LKJQ0oERsYscUMH8So false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20434 uniprotkb:P54839 intact:EBI-15781|uniprotkb:Q02121|ensemblfungi:YBR154C|uniprotkb:D6VQE9 intact:EBI-8373|uniprotkb:D6W0F9|ensemblfungi:YML126C psi-mi:rpab1_yeast(display_long)|uniprotkb:RPB5(gene name)|psi-mi:RPB5(display_short)|uniprotkb:YBR154C(locus name)|uniprotkb:YBR1204(orf name)|uniprotkb:RPA7(gene name synonym)|uniprotkb:RPC9(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide(gene name synonym)|uniprotkb:ABC27(gene name synonym) psi-mi:hmcs_yeast(display_long)|uniprotkb:ERG13(gene name)|psi-mi:ERG13(display_short)|uniprotkb:HMGS(gene name synonym)|uniprotkb:YML126C(locus name)|uniprotkb:YM4987.09C(orf name)|uniprotkb:3-hydroxy-3-methylglutaryl coenzyme A synthase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339473|imex:IM-14275-2322 author score:99.36 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|rcsb pdb:1WCM|rcsb pdb:1Y1V|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|rcsb pdb:2B63|rcsb pdb:2B8K|interpro:IPR020608|interpro:IPR020609|rcsb pdb:2E2H|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:1DZF|rcsb pdb:1I3Q|rcsb pdb:2E2I|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:5M5Y|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6H67|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:2E2J|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|ensemblfungi:YBR154C(gene)|ensemblfungi:YBR154C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4V1M|rcsb pdb:2JA5|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2JA6|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:2JA7|rcsb pdb:3GTG|rcsb pdb:2JA8|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:2NVQ|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4YM7|rcsb pdb:5C3E|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5G5L|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6H68|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|rcsb pdb:6UQ2|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-77075|reactome:R-SCE-9018519|refseq:NP_009712.1|sgd:S000000358|dip:DIP-71N|mint:P20434 refseq:NP_013580.1|sgd:S000004595|mint:P54839|dip:DIP-5071N|ensemblfungi:YML126C(gene)|ensemblfungi:YML126C_mRNA(transcript)|go:"GO:0004421"(hydroxymethylglutaryl-CoA synthase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0010142"(farnesyl diphosphate biosynthetic process, mevalonate pathway)|interpro:IPR000590(Hydroxymethylglutaryl-coenzyme A synthase, active site)|interpro:IPR010122(Hydroxymethylglutaryl-CoA synthase, eukaryotic)|interpro:IPR013528(Hydroxymethylglutaryl-coenzyme A synthase, N-terminal)|interpro:IPR013746(Hydroxymethylglutaryl-coenzyme A synthase C-terminal)|interpro:IPR016039(Thiolase-like)|reactome:R-SCE-191273|reactome:R-SCE-77111 psi-mi:"MI:0469"(intact) crc64:2A15F7114D69D829 crc64:44DFF3C0B0356D9E figure legend:tables S3 and S4|author-confidence:99.36|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:j/jAJ2fXWf4ebK1aWTWrKERGUpM559292 rogid:xE3CIPqDOfyrlrhqbi9jlTebNwI559292 intact-crc:E738DB3946B11C41|rigid:43a2XYkQoN4wMr03snCnJoVHHEU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54858 uniprotkb:P54858 intact:EBI-6042|uniprotkb:D6VS54|ensemblfungi:YDR068W intact:EBI-6042|uniprotkb:D6VS54|ensemblfungi:YDR068W psi-mi:dos2_yeast(display_long)|uniprotkb:D4267(orf name)|uniprotkb:YD8554.01(orf name)|uniprotkb:YD9609.22(orf name)|uniprotkb:DOS2(gene name)|psi-mi:DOS2(display_short)|uniprotkb:YDR068W(locus name) psi-mi:dos2_yeast(display_long)|uniprotkb:D4267(orf name)|uniprotkb:YD8554.01(orf name)|uniprotkb:YD9609.22(orf name)|uniprotkb:DOS2(gene name)|psi-mi:DOS2(display_short)|uniprotkb:YDR068W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339484|imex:IM-14275-2323 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002475|refseq:NP_010353.3|dip:DIP-4785N|mint:P54858|ensemblfungi:YDR068W(gene)|ensemblfungi:YDR068W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR005607(BSD)|interpro:IPR035925 sgd:S000002475|refseq:NP_010353.3|dip:DIP-4785N|mint:P54858|ensemblfungi:YDR068W(gene)|ensemblfungi:YDR068W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR005607(BSD)|interpro:IPR035925 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:/4fnAAPmC12DMUbUB8MVS9yjjeg559292 rogid:/4fnAAPmC12DMUbUB8MVS9yjjeg559292 intact-crc:F4CED7F28B66F5D7|rigid:JPbQp4u1BZ8HXBgGBjE5V+jFdLc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54858 uniprotkb:Q12270 intact:EBI-6042|uniprotkb:D6VS54|ensemblfungi:YDR068W intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:dos2_yeast(display_long)|uniprotkb:D4267(orf name)|uniprotkb:YD8554.01(orf name)|uniprotkb:YD9609.22(orf name)|uniprotkb:DOS2(gene name)|psi-mi:DOS2(display_short)|uniprotkb:YDR068W(locus name) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339495|imex:IM-14275-2324 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002475|refseq:NP_010353.3|dip:DIP-4785N|mint:P54858|ensemblfungi:YDR068W(gene)|ensemblfungi:YDR068W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR005607(BSD)|interpro:IPR035925 refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:/4fnAAPmC12DMUbUB8MVS9yjjeg559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:4A3D4B541E73CAC9|rigid:MsMYPhMeNv4t9WPKuJbTBLc7Xk8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17423 uniprotkb:P54861 intact:EBI-9685|ensemblfungi:YHR025W|uniprotkb:D3DKX2 intact:EBI-6002|uniprotkb:D6VY02|ensemblfungi:YLL001W psi-mi:khse_yeast(display_long)|uniprotkb:THR1(gene name)|psi-mi:THR1(display_short)|uniprotkb:YHR025W(locus name) psi-mi:dnm1_yeast(display_long)|uniprotkb:L1381(orf name)|uniprotkb:YLL001W(locus name)|uniprotkb:DNM1(gene name)|psi-mi:DNM1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339506|imex:IM-14275-2325 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR025W(gene)|ensemblfungi:YHR025W_mRNA(transcript)|go:"GO:0004413"(homoserine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0009088"(threonine biosynthetic process)|go:"GO:0009092"(homoserine metabolic process)|interpro:IPR000870(Homoserine kinase)|interpro:IPR006203(GHMP kinase, ATP-binding, conserved site)|interpro:IPR006204(GHMP kinase)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR036554|refseq:NP_011890.1|sgd:S000001067|dip:DIP-4305N|mint:P17423 refseq:NP_013100.1|sgd:S000003924|dip:DIP-1908N|mint:P54861|ensemblfungi:YLL001W(gene)|ensemblfungi:YLL001W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015886"(heme transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|reactome:R-SCE-169911|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-75153|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) - crc64:EBEF8793C5951770 figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:S6tiEUJn7YZY4ydBnYraAdecCRY559292 rogid:1MUFRBj6HOLvJRrwVSYe7afG/1s559292 intact-crc:8787C196427064A8|rigid:/BmGdSxD8RYhOMu2ryjcGX0WmtQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33327 uniprotkb:P54861 intact:EBI-5815|ensemblfungi:YDL215C|uniprotkb:D6VRD9 intact:EBI-6002|uniprotkb:D6VY02|ensemblfungi:YLL001W psi-mi:dhe2_yeast(display_long)|uniprotkb:YDL215C(locus name)|uniprotkb:GDH2(gene name)|psi-mi:GDH2(display_short)|uniprotkb:D0892(orf name) psi-mi:dnm1_yeast(display_long)|uniprotkb:L1381(orf name)|uniprotkb:YLL001W(locus name)|uniprotkb:DNM1(gene name)|psi-mi:DNM1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339517|imex:IM-14275-2326 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDL215C(gene)|ensemblfungi:YDL215C_mRNA(transcript)|go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0019551"(glutamate catabolic process to 2-oxoglutarate)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR016210(Glutamate dehydrogenase, NAD-dependent)|interpro:IPR033524|interpro:IPR036291|refseq:NP_010066.1|sgd:S000002374|dip:DIP-1689N|mint:P33327 refseq:NP_013100.1|sgd:S000003924|dip:DIP-1908N|mint:P54861|ensemblfungi:YLL001W(gene)|ensemblfungi:YLL001W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015886"(heme transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|reactome:R-SCE-169911|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-75153|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:DF8358D831E4545F crc64:EBEF8793C5951770 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:bjvKAO4gyrNUq2Wwq3Y+FvEv7RM559292 rogid:1MUFRBj6HOLvJRrwVSYe7afG/1s559292 intact-crc:F38795BE75892530|rigid:khELOGCBTuAp/pl1qowidSkoWlQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41811 uniprotkb:P54861 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W intact:EBI-6002|uniprotkb:D6VY02|ensemblfungi:YLL001W psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:dnm1_yeast(display_long)|uniprotkb:L1381(orf name)|uniprotkb:YLL001W(locus name)|uniprotkb:DNM1(gene name)|psi-mi:DNM1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339528|imex:IM-14275-2327 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_013100.1|sgd:S000003924|dip:DIP-1908N|mint:P54861|ensemblfungi:YLL001W(gene)|ensemblfungi:YLL001W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015886"(heme transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|reactome:R-SCE-169911|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-75153|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:6A5E50BBEB02CB58 crc64:EBEF8793C5951770 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 rogid:1MUFRBj6HOLvJRrwVSYe7afG/1s559292 intact-crc:A5A218EBD073DB37|rigid:P1xjaoT/fY+ycY+Dm2dJmj29j6c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54861 uniprotkb:P54783 intact:EBI-6002|uniprotkb:D6VY02|ensemblfungi:YLL001W intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 psi-mi:dnm1_yeast(display_long)|uniprotkb:L1381(orf name)|uniprotkb:YLL001W(locus name)|uniprotkb:DNM1(gene name)|psi-mi:DNM1(display_short) psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339539|imex:IM-14275-2328 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013100.1|sgd:S000003924|dip:DIP-1908N|mint:P54861|ensemblfungi:YLL001W(gene)|ensemblfungi:YLL001W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015886"(heme transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|reactome:R-SCE-169911|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-75153|reactome:R-SCE-8856828 go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 psi-mi:"MI:0469"(intact) crc64:EBEF8793C5951770 - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1MUFRBj6HOLvJRrwVSYe7afG/1s559292 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 intact-crc:E983E888EAEC9105|rigid:jt6Lo8AQ21/8CgN52NB+QOn1n4Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54861 uniprotkb:P54858 intact:EBI-6002|uniprotkb:D6VY02|ensemblfungi:YLL001W intact:EBI-6042|uniprotkb:D6VS54|ensemblfungi:YDR068W psi-mi:dnm1_yeast(display_long)|uniprotkb:L1381(orf name)|uniprotkb:YLL001W(locus name)|uniprotkb:DNM1(gene name)|psi-mi:DNM1(display_short) psi-mi:dos2_yeast(display_long)|uniprotkb:D4267(orf name)|uniprotkb:YD8554.01(orf name)|uniprotkb:YD9609.22(orf name)|uniprotkb:DOS2(gene name)|psi-mi:DOS2(display_short)|uniprotkb:YDR068W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339550|imex:IM-14275-2329 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013100.1|sgd:S000003924|dip:DIP-1908N|mint:P54861|ensemblfungi:YLL001W(gene)|ensemblfungi:YLL001W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015886"(heme transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|reactome:R-SCE-169911|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-75153|reactome:R-SCE-8856828 sgd:S000002475|refseq:NP_010353.3|dip:DIP-4785N|mint:P54858|ensemblfungi:YDR068W(gene)|ensemblfungi:YDR068W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR005607(BSD)|interpro:IPR035925 psi-mi:"MI:0469"(intact) crc64:EBEF8793C5951770 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1MUFRBj6HOLvJRrwVSYe7afG/1s559292 rogid:/4fnAAPmC12DMUbUB8MVS9yjjeg559292 intact-crc:949EB4C0F5337148|rigid:VF0JQoBAMXEDtxo+43GyPFMJllE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54861 uniprotkb:P54861 intact:EBI-6002|uniprotkb:D6VY02|ensemblfungi:YLL001W intact:EBI-6002|uniprotkb:D6VY02|ensemblfungi:YLL001W psi-mi:dnm1_yeast(display_long)|uniprotkb:L1381(orf name)|uniprotkb:YLL001W(locus name)|uniprotkb:DNM1(gene name)|psi-mi:DNM1(display_short) psi-mi:dnm1_yeast(display_long)|uniprotkb:L1381(orf name)|uniprotkb:YLL001W(locus name)|uniprotkb:DNM1(gene name)|psi-mi:DNM1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339561|imex:IM-14275-2330 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013100.1|sgd:S000003924|dip:DIP-1908N|mint:P54861|ensemblfungi:YLL001W(gene)|ensemblfungi:YLL001W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015886"(heme transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|reactome:R-SCE-169911|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-75153|reactome:R-SCE-8856828 refseq:NP_013100.1|sgd:S000003924|dip:DIP-1908N|mint:P54861|ensemblfungi:YLL001W(gene)|ensemblfungi:YLL001W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015886"(heme transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|reactome:R-SCE-169911|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-75153|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:EBEF8793C5951770 crc64:EBEF8793C5951770 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1MUFRBj6HOLvJRrwVSYe7afG/1s559292 rogid:1MUFRBj6HOLvJRrwVSYe7afG/1s559292 intact-crc:ADFC4ED9B02C953C|rigid:uG17nS0CWL2Kv8CwodE65HRVC+w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54885 uniprotkb:P41811 intact:EBI-13872|ensemblfungi:YOR323C|uniprotkb:D6W321 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:proa_yeast(display_long)|uniprotkb:PRO2(gene name)|psi-mi:PRO2(display_short)|uniprotkb:YOR323C(locus name)|uniprotkb:O6155(orf name)|uniprotkb:Glutamate-5-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:Glutamyl-gamma-semialdehyde dehydrogenase(gene name synonym) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339572|imex:IM-14275-2331 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR323C(gene)|go:"GO:0004350"(glutamate-5-semialdehyde dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0050661"(NADP binding)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR012134(Glutamate-5-semialdehyde dehydrogenase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR020593|rcsb pdb:1VLU|reactome:R-SCE-8964539|ensemblfungi:YOR323C_mRNA(transcript)|refseq:NP_014968.1|sgd:S000005850|mint:P54885|dip:DIP-6586N refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:7EDEC40C9B3DB07D crc64:6A5E50BBEB02CB58 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WYV0kEZ3J5Aw2u3Eye0h2Rmo4lg559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:767A6A10A2513953|rigid:+z0sJB307gIS6sQgk01ZYVe750U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54885 uniprotkb:P54885 intact:EBI-13872|ensemblfungi:YOR323C|uniprotkb:D6W321 intact:EBI-13872|ensemblfungi:YOR323C|uniprotkb:D6W321 psi-mi:proa_yeast(display_long)|uniprotkb:PRO2(gene name)|psi-mi:PRO2(display_short)|uniprotkb:YOR323C(locus name)|uniprotkb:O6155(orf name)|uniprotkb:Glutamate-5-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:Glutamyl-gamma-semialdehyde dehydrogenase(gene name synonym) psi-mi:proa_yeast(display_long)|uniprotkb:PRO2(gene name)|psi-mi:PRO2(display_short)|uniprotkb:YOR323C(locus name)|uniprotkb:O6155(orf name)|uniprotkb:Glutamate-5-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:Glutamyl-gamma-semialdehyde dehydrogenase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339583|imex:IM-14275-2332 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR323C(gene)|go:"GO:0004350"(glutamate-5-semialdehyde dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0050661"(NADP binding)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR012134(Glutamate-5-semialdehyde dehydrogenase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR020593|rcsb pdb:1VLU|reactome:R-SCE-8964539|ensemblfungi:YOR323C_mRNA(transcript)|refseq:NP_014968.1|sgd:S000005850|mint:P54885|dip:DIP-6586N ensemblfungi:YOR323C(gene)|go:"GO:0004350"(glutamate-5-semialdehyde dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0050661"(NADP binding)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR012134(Glutamate-5-semialdehyde dehydrogenase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR020593|rcsb pdb:1VLU|reactome:R-SCE-8964539|ensemblfungi:YOR323C_mRNA(transcript)|refseq:NP_014968.1|sgd:S000005850|mint:P54885|dip:DIP-6586N psi-mi:"MI:0469"(intact) crc64:7EDEC40C9B3DB07D crc64:7EDEC40C9B3DB07D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WYV0kEZ3J5Aw2u3Eye0h2Rmo4lg559292 rogid:WYV0kEZ3J5Aw2u3Eye0h2Rmo4lg559292 intact-crc:B26A3C30098CCFC3|rigid:mZbpmeudAK1aGvtEMcUtuCYDi3g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02309 uniprotkb:P61830 intact:EBI-8113|uniprotkb:D6VQ10|ensemblfungi:YBR009C|ensemblfungi:YNL030W intact:EBI-8098|uniprotkb:E9PAG1|uniprotkb:P02303|uniprotkb:P13996|uniprotkb:Q6B1U3|uniprotkb:Q6Q7G9|uniprotkb:D6VQ11|ensemblfungi:YBR010W|ensemblfungi:YNL031C psi-mi:h4_yeast(display_long)|uniprotkb:N2752(orf name)|uniprotkb:YBR0122(orf name)|uniprotkb:YBR009C(locus name)|uniprotkb:YNL030W(locus name)|uniprotkb:HHF1(gene name)|psi-mi:HHF1(display_short)|uniprotkb:HHF2(gene name)|psi-mi:HHF2(display_short) psi-mi:h3_yeast(display_long)|uniprotkb:SIN2(gene name synonym)|uniprotkb:YNL031C(locus name)|uniprotkb:N2749(orf name)|uniprotkb:HHT1(gene name)|psi-mi:HHT1(display_short)|uniprotkb:YBR010W(locus name)|uniprotkb:YBR0201(orf name)|uniprotkb:HHT2(gene name)|psi-mi:HHT2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339594|imex:IM-14275-2333 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009563.1|refseq:NP_014368.1|sgd:S000000213|sgd:S000004975|dip:DIP-418N|mint:P02309|ensemblfungi:YBR009C(gene)|ensemblfungi:YBR009C_mRNA(transcript)|ensemblfungi:YNL030W(gene)|ensemblfungi:YNL030W_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|interpro:IPR001951(Histone H4)|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|rcsb pdb:1E6I|rcsb pdb:1ID3|rcsb pdb:1Q1A|rcsb pdb:1SZC|rcsb pdb:1SZD|rcsb pdb:2DVQ|rcsb pdb:2DVR|rcsb pdb:2E3K|rcsb pdb:2FSB|rcsb pdb:2H2H|rcsb pdb:2L5A|rcsb pdb:2QQF|rcsb pdb:2QQG|rcsb pdb:3TO6|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:4TWI|rcsb pdb:4TWJ|rcsb pdb:5W0V|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6QLD|rcsb pdb:6RXJ|rcsb pdb:6RXK|rcsb pdb:6RXL|rcsb pdb:6RXM|rcsb pdb:6RXO|rcsb pdb:6RXP|rcsb pdb:6RXQ|rcsb pdb:6RXR|rcsb pdb:7K78|rcsb pdb:7K7G|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-3214842|reactome:R-SCE-3214847|reactome:R-SCE-3214858|reactome:R-SCE-4551638|reactome:R-SCE-9018519 refseq:NP_009564.1|refseq:NP_014367.1|sgd:S000000214|sgd:S000004976|mint:P61830|dip:DIP-417N|ensemblfungi:YBR010W(gene)|ensemblfungi:YBR010W_mRNA(transcript)|ensemblfungi:YNL031C(gene)|ensemblfungi:YNL031C_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:1ID3|rcsb pdb:1M1D|rcsb pdb:1PEG|rcsb pdb:1PU9|rcsb pdb:1PUA|rcsb pdb:1QSN|rcsb pdb:2CNX|rcsb pdb:2H2G|rcsb pdb:2IDC|rcsb pdb:2JMJ|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:2RSN|rcsb pdb:3MP1|rcsb pdb:3MP6|rcsb pdb:3Q33|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6J2P|rcsb pdb:6KMJ|rcsb pdb:7K7G psi-mi:"MI:0469"(intact) crc64:69B7D1F89E62DE41 crc64:A6115FEB480AC67A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wGtUrumyxGKsW9BEzkBW3FwvwUo559292 rogid:jtDVNjrs2tJMmr/dqrvnNiQ2ppQ559292 intact-crc:2697FA039D809987|rigid:MBBZpF6i3n5Gw+ZjhZ0xSmuMkJI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27999 uniprotkb:P61830 intact:EBI-15798|ensemblfungi:YGL070C|uniprotkb:D6VU72 intact:EBI-8098|uniprotkb:E9PAG1|uniprotkb:P02303|uniprotkb:P13996|uniprotkb:Q6B1U3|uniprotkb:Q6Q7G9|uniprotkb:D6VQ11|ensemblfungi:YBR010W|ensemblfungi:YNL031C psi-mi:rpb9_yeast(display_long)|uniprotkb:YGL070C(locus name)|uniprotkb:RPB9(gene name)|psi-mi:RPB9(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit 9(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 14.2 kDa polypeptide(gene name synonym)|uniprotkb:B12.6(gene name synonym) psi-mi:h3_yeast(display_long)|uniprotkb:SIN2(gene name synonym)|uniprotkb:YNL031C(locus name)|uniprotkb:N2749(orf name)|uniprotkb:HHT1(gene name)|psi-mi:HHT1(display_short)|uniprotkb:YBR010W(locus name)|uniprotkb:YBR0201(orf name)|uniprotkb:HHT2(gene name)|psi-mi:HHT2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339605|imex:IM-14275-2334 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4BY7|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4A3E|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4A3F|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:4A3G|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:4A3K|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:4A3L|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|ensemblfungi:YGL070C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|ensemblfungi:YGL070C(gene)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3GTM|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:1TWH|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:5VVR|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|refseq:NP_011445.1|sgd:S000003038|dip:DIP-610N|mint:P27999 refseq:NP_009564.1|refseq:NP_014367.1|sgd:S000000214|sgd:S000004976|mint:P61830|dip:DIP-417N|ensemblfungi:YBR010W(gene)|ensemblfungi:YBR010W_mRNA(transcript)|ensemblfungi:YNL031C(gene)|ensemblfungi:YNL031C_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:1ID3|rcsb pdb:1M1D|rcsb pdb:1PEG|rcsb pdb:1PU9|rcsb pdb:1PUA|rcsb pdb:1QSN|rcsb pdb:2CNX|rcsb pdb:2H2G|rcsb pdb:2IDC|rcsb pdb:2JMJ|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:2RSN|rcsb pdb:3MP1|rcsb pdb:3MP6|rcsb pdb:3Q33|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6J2P|rcsb pdb:6KMJ|rcsb pdb:7K7G psi-mi:"MI:0469"(intact) crc64:A80D69678A722881 crc64:A6115FEB480AC67A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1j6EwrXe8/AF0PL2VTiTTCfWJDM559292 rogid:jtDVNjrs2tJMmr/dqrvnNiQ2ppQ559292 intact-crc:4D259F387EFAABA3|rigid:5stZARCtjApGaKl+0PCj2DmITRw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32447 uniprotkb:P61830 intact:EBI-3003|uniprotkb:D6VW69|ensemblfungi:YJL115W intact:EBI-8098|uniprotkb:E9PAG1|uniprotkb:P02303|uniprotkb:P13996|uniprotkb:Q6B1U3|uniprotkb:Q6Q7G9|uniprotkb:D6VQ11|ensemblfungi:YBR010W|ensemblfungi:YNL031C psi-mi:asf1_yeast(display_long)|uniprotkb:ASF1(gene name)|psi-mi:ASF1(display_short)|uniprotkb:YJL115W(locus name)|uniprotkb:J0755(orf name)|uniprotkb:CIA1(gene name synonym)|uniprotkb:Anti-silencing function protein 1(gene name synonym) psi-mi:h3_yeast(display_long)|uniprotkb:SIN2(gene name synonym)|uniprotkb:YNL031C(locus name)|uniprotkb:N2749(orf name)|uniprotkb:HHT1(gene name)|psi-mi:HHT1(display_short)|uniprotkb:YBR010W(locus name)|uniprotkb:YBR0201(orf name)|uniprotkb:HHT2(gene name)|psi-mi:HHT2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339616|imex:IM-14275-2335 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012420.1|sgd:S000003651|dip:DIP-2675N|mint:P32447|ensemblfungi:YJL115W(gene)|ensemblfungi:YJL115W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006348"|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0043486"(histone exchange)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0070775"(H3 histone acetyltransferase complex)|go:"GO:0097043"(histone H3-K56 acetylation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR017282(Histone deposition protein Asf1)|interpro:IPR036747|rcsb pdb:1ROC|rcsb pdb:1WG3|rcsb pdb:2HUE|rcsb pdb:2IDC|rcsb pdb:2YGV|rcsb pdb:4EO5|rcsb pdb:4ZBJ|rcsb pdb:5EII|rcsb pdb:5UCB|rcsb pdb:5UEA|rcsb pdb:5UEK|rcsb pdb:6AYZ|rcsb pdb:6AZ2|rcsb pdb:6F0Y|rcsb pdb:6O22|reactome:R-SCE-2559584 refseq:NP_009564.1|refseq:NP_014367.1|sgd:S000000214|sgd:S000004976|mint:P61830|dip:DIP-417N|ensemblfungi:YBR010W(gene)|ensemblfungi:YBR010W_mRNA(transcript)|ensemblfungi:YNL031C(gene)|ensemblfungi:YNL031C_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:1ID3|rcsb pdb:1M1D|rcsb pdb:1PEG|rcsb pdb:1PU9|rcsb pdb:1PUA|rcsb pdb:1QSN|rcsb pdb:2CNX|rcsb pdb:2H2G|rcsb pdb:2IDC|rcsb pdb:2JMJ|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:2RSN|rcsb pdb:3MP1|rcsb pdb:3MP6|rcsb pdb:3Q33|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6J2P|rcsb pdb:6KMJ|rcsb pdb:7K7G psi-mi:"MI:0469"(intact) crc64:186E76075C0B1644 crc64:A6115FEB480AC67A figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:En27z1xiUMZBu18Nq9rrAsUy5Zs559292 rogid:jtDVNjrs2tJMmr/dqrvnNiQ2ppQ559292 intact-crc:2D5EAD6C48B3DE1B|rigid:8Lmu30kwNZZd9XkqWbamKKXmaZg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61830 uniprotkb:P53551 intact:EBI-8098|uniprotkb:E9PAG1|uniprotkb:P02303|uniprotkb:P13996|uniprotkb:Q6B1U3|uniprotkb:Q6Q7G9|uniprotkb:D6VQ11|ensemblfungi:YBR010W|ensemblfungi:YNL031C intact:EBI-8064|uniprotkb:Q6Q5R6|uniprotkb:D6W3P0|ensemblfungi:YPL127C psi-mi:h3_yeast(display_long)|uniprotkb:SIN2(gene name synonym)|uniprotkb:YNL031C(locus name)|uniprotkb:N2749(orf name)|uniprotkb:HHT1(gene name)|psi-mi:HHT1(display_short)|uniprotkb:YBR010W(locus name)|uniprotkb:YBR0201(orf name)|uniprotkb:HHT2(gene name)|psi-mi:HHT2(display_short) psi-mi:h1_yeast(display_long)|uniprotkb:HHO1(gene name)|psi-mi:HHO1(display_short)|uniprotkb:LPI17C(orf name)|uniprotkb:YPL127C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339627|imex:IM-14275-2336 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009564.1|refseq:NP_014367.1|sgd:S000000214|sgd:S000004976|mint:P61830|dip:DIP-417N|ensemblfungi:YBR010W(gene)|ensemblfungi:YBR010W_mRNA(transcript)|ensemblfungi:YNL031C(gene)|ensemblfungi:YNL031C_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:1ID3|rcsb pdb:1M1D|rcsb pdb:1PEG|rcsb pdb:1PU9|rcsb pdb:1PUA|rcsb pdb:1QSN|rcsb pdb:2CNX|rcsb pdb:2H2G|rcsb pdb:2IDC|rcsb pdb:2JMJ|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:2RSN|rcsb pdb:3MP1|rcsb pdb:3MP6|rcsb pdb:3Q33|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6J2P|rcsb pdb:6KMJ|rcsb pdb:7K7G refseq:NP_015198.1|sgd:S000006048|mint:P53551|dip:DIP-6587N|ensemblfungi:YPL127C(gene)|ensemblfungi:YPL127C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0097100"(supercoiled DNA binding)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1UHM|rcsb pdb:1USS|rcsb pdb:1UST|rcsb pdb:1YQA psi-mi:"MI:0469"(intact) crc64:A6115FEB480AC67A crc64:B0C53AC186E49F96 figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jtDVNjrs2tJMmr/dqrvnNiQ2ppQ559292 rogid:dPMYSAq1Cr7pfGGNgb3GDp3LnsQ559292 intact-crc:16A22575851F4FD0|rigid:T9OVg9VYs8RO1ZP6HqKlbrMadBw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61830 uniprotkb:P61830 intact:EBI-8098|uniprotkb:E9PAG1|uniprotkb:P02303|uniprotkb:P13996|uniprotkb:Q6B1U3|uniprotkb:Q6Q7G9|uniprotkb:D6VQ11|ensemblfungi:YBR010W|ensemblfungi:YNL031C intact:EBI-8098|uniprotkb:E9PAG1|uniprotkb:P02303|uniprotkb:P13996|uniprotkb:Q6B1U3|uniprotkb:Q6Q7G9|uniprotkb:D6VQ11|ensemblfungi:YBR010W|ensemblfungi:YNL031C psi-mi:h3_yeast(display_long)|uniprotkb:SIN2(gene name synonym)|uniprotkb:YNL031C(locus name)|uniprotkb:N2749(orf name)|uniprotkb:HHT1(gene name)|psi-mi:HHT1(display_short)|uniprotkb:YBR010W(locus name)|uniprotkb:YBR0201(orf name)|uniprotkb:HHT2(gene name)|psi-mi:HHT2(display_short) psi-mi:h3_yeast(display_long)|uniprotkb:SIN2(gene name synonym)|uniprotkb:YNL031C(locus name)|uniprotkb:N2749(orf name)|uniprotkb:HHT1(gene name)|psi-mi:HHT1(display_short)|uniprotkb:YBR010W(locus name)|uniprotkb:YBR0201(orf name)|uniprotkb:HHT2(gene name)|psi-mi:HHT2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339638|imex:IM-14275-2337 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009564.1|refseq:NP_014367.1|sgd:S000000214|sgd:S000004976|mint:P61830|dip:DIP-417N|ensemblfungi:YBR010W(gene)|ensemblfungi:YBR010W_mRNA(transcript)|ensemblfungi:YNL031C(gene)|ensemblfungi:YNL031C_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:1ID3|rcsb pdb:1M1D|rcsb pdb:1PEG|rcsb pdb:1PU9|rcsb pdb:1PUA|rcsb pdb:1QSN|rcsb pdb:2CNX|rcsb pdb:2H2G|rcsb pdb:2IDC|rcsb pdb:2JMJ|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:2RSN|rcsb pdb:3MP1|rcsb pdb:3MP6|rcsb pdb:3Q33|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6J2P|rcsb pdb:6KMJ|rcsb pdb:7K7G refseq:NP_009564.1|refseq:NP_014367.1|sgd:S000000214|sgd:S000004976|mint:P61830|dip:DIP-417N|ensemblfungi:YBR010W(gene)|ensemblfungi:YBR010W_mRNA(transcript)|ensemblfungi:YNL031C(gene)|ensemblfungi:YNL031C_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:1ID3|rcsb pdb:1M1D|rcsb pdb:1PEG|rcsb pdb:1PU9|rcsb pdb:1PUA|rcsb pdb:1QSN|rcsb pdb:2CNX|rcsb pdb:2H2G|rcsb pdb:2IDC|rcsb pdb:2JMJ|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:2RSN|rcsb pdb:3MP1|rcsb pdb:3MP6|rcsb pdb:3Q33|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6J2P|rcsb pdb:6KMJ|rcsb pdb:7K7G psi-mi:"MI:0469"(intact) crc64:A6115FEB480AC67A crc64:A6115FEB480AC67A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jtDVNjrs2tJMmr/dqrvnNiQ2ppQ559292 rogid:jtDVNjrs2tJMmr/dqrvnNiQ2ppQ559292 intact-crc:4C309CDA9EB75C69|rigid:2bMAiFUraj/XsrKJpxnjZaOvjYg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61830 uniprotkb:Q12373 intact:EBI-8098|uniprotkb:E9PAG1|uniprotkb:P02303|uniprotkb:P13996|uniprotkb:Q6B1U3|uniprotkb:Q6Q7G9|uniprotkb:D6VQ11|ensemblfungi:YBR010W|ensemblfungi:YNL031C intact:EBI-31911|uniprotkb:D6VXY2|ensemblfungi:YLL022C psi-mi:h3_yeast(display_long)|uniprotkb:SIN2(gene name synonym)|uniprotkb:YNL031C(locus name)|uniprotkb:N2749(orf name)|uniprotkb:HHT1(gene name)|psi-mi:HHT1(display_short)|uniprotkb:YBR010W(locus name)|uniprotkb:YBR0201(orf name)|uniprotkb:HHT2(gene name)|psi-mi:HHT2(display_short) psi-mi:hif1_yeast(display_long)|uniprotkb:HIF1(gene name)|psi-mi:HIF1(display_short)|uniprotkb:L1205(orf name)|uniprotkb:YLL022C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339649|imex:IM-14275-2338 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009564.1|refseq:NP_014367.1|sgd:S000000214|sgd:S000004976|mint:P61830|dip:DIP-417N|ensemblfungi:YBR010W(gene)|ensemblfungi:YBR010W_mRNA(transcript)|ensemblfungi:YNL031C(gene)|ensemblfungi:YNL031C_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:1ID3|rcsb pdb:1M1D|rcsb pdb:1PEG|rcsb pdb:1PU9|rcsb pdb:1PUA|rcsb pdb:1QSN|rcsb pdb:2CNX|rcsb pdb:2H2G|rcsb pdb:2IDC|rcsb pdb:2JMJ|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:2RSN|rcsb pdb:3MP1|rcsb pdb:3MP6|rcsb pdb:3Q33|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6J2P|rcsb pdb:6KMJ|rcsb pdb:7K7G refseq:NP_013078.1|sgd:S000003945|dip:DIP-6442N|mint:Q12373|ensemblfungi:YLL022C(gene)|ensemblfungi:YLL022C_mRNA(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006348"|go:"GO:0016573"(histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:4NQ0|rcsb pdb:5BT1 psi-mi:"MI:0469"(intact) crc64:A6115FEB480AC67A crc64:B280CFCCB6896506 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jtDVNjrs2tJMmr/dqrvnNiQ2ppQ559292 rogid:4bOpAXdlDl6LtBQ+BjueT5/24aA559292 intact-crc:84225876280ACCC4|rigid:xkLIoVjhyqGhiIpFfIoliQK5BtI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P69771 uniprotkb:P39929 intact:EBI-2053489|uniprotkb:D6VX98|ensemblfungi:YKR035W-A intact:EBI-17554|uniprotkb:D6VY27|ensemblfungi:YLR025W|uniprotkb:E9P8V6 psi-mi:did2_yeast(display_long)|uniprotkb:CHM1(gene name synonym)|uniprotkb:FTI1(gene name synonym)|uniprotkb:Fifty two inhibitor 1(gene name synonym)|uniprotkb:YKR035W-A(locus name)|uniprotkb:VPS46(gene name synonym)|uniprotkb:Charged multivesicular body protein 1(gene name synonym)|uniprotkb:DOA4-independent degradation protein 2(gene name synonym)|uniprotkb:DID2(gene name)|psi-mi:DID2(display_short) psi-mi:snf7_yeast(display_long)|uniprotkb:SNF7(gene name)|psi-mi:SNF7(display_short)|uniprotkb:VPS32(gene name synonym)|uniprotkb:YLR025W(locus name)|uniprotkb:DID1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 32(gene name synonym)|uniprotkb:DOA4-independent degradation protein 1(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 7(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339660|imex:IM-14275-2339 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006435|refseq:NP_012961.3|dip:DIP-52223N|mint:P69771|ensemblfungi:YKR035W-A(gene)|ensemblfungi:YKR035W-A_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|rcsb pdb:3GGZ|rcsb pdb:5H7P refseq:NP_013125.1|sgd:S000004015|ensemblfungi:YLR025W(gene)|ensemblfungi:YLR025W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0071454"(cellular response to anoxia)|go:"GO:1904669"(ATP export)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|rcsb pdb:5FD7|rcsb pdb:5FD9|rcsb pdb:5T8L|rcsb pdb:5T8N|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1747N|mint:P39929 psi-mi:"MI:0469"(intact) crc64:70D1CF4588A8C6E6 crc64:5241A18BB181F0C1 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SVI1+8lRI6qwD0CSLY11Xq0LG0o559292 rogid:I8qBtNlqTjxLX1HginTOzM3o9oA559292 intact-crc:EAC37F892A2FBBC4|rigid:/9MgoWCRMe1bTvMXCfrstizhNXU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53843 uniprotkb:P69771 intact:EBI-28245|uniprotkb:D6W0S8|ensemblfungi:YNL265C intact:EBI-2053489|uniprotkb:D6VX98|ensemblfungi:YKR035W-A psi-mi:ist1_yeast(display_long)|uniprotkb:YNL265C(locus name)|uniprotkb:N0809(orf name)|uniprotkb:IST1(gene name)|psi-mi:IST1(display_short)|uniprotkb:Increased sodium tolerance protein 1(gene name synonym) psi-mi:did2_yeast(display_long)|uniprotkb:CHM1(gene name synonym)|uniprotkb:FTI1(gene name synonym)|uniprotkb:Fifty two inhibitor 1(gene name synonym)|uniprotkb:YKR035W-A(locus name)|uniprotkb:VPS46(gene name synonym)|uniprotkb:Charged multivesicular body protein 1(gene name synonym)|uniprotkb:DOA4-independent degradation protein 2(gene name synonym)|uniprotkb:DID2(gene name)|psi-mi:DID2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339671|imex:IM-14275-2340 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014134.1|sgd:S000005209|dip:DIP-6713N|mint:P53843|ensemblfungi:YNL265C(gene)|ensemblfungi:YNL265C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|interpro:IPR005061(Protein of unknown function DUF292, eukaryotic)|interpro:IPR042277|rcsb pdb:3GGY|rcsb pdb:3GGZ|reactome:R-SCE-6798695|reactome:R-SCE-9668328 sgd:S000006435|refseq:NP_012961.3|dip:DIP-52223N|mint:P69771|ensemblfungi:YKR035W-A(gene)|ensemblfungi:YKR035W-A_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|rcsb pdb:3GGZ|rcsb pdb:5H7P psi-mi:"MI:0469"(intact) - crc64:70D1CF4588A8C6E6 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:c8ngH6tobftaOGIxLH8qXiOpi28559292 rogid:SVI1+8lRI6qwD0CSLY11Xq0LG0o559292 intact-crc:08ECBD0CE69BCDF2|rigid:B99gmwNEnTICzDD4Ci/ZeLVO5gg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P69771 uniprotkb:P69771 intact:EBI-2053489|uniprotkb:D6VX98|ensemblfungi:YKR035W-A intact:EBI-2053489|uniprotkb:D6VX98|ensemblfungi:YKR035W-A psi-mi:did2_yeast(display_long)|uniprotkb:CHM1(gene name synonym)|uniprotkb:FTI1(gene name synonym)|uniprotkb:Fifty two inhibitor 1(gene name synonym)|uniprotkb:YKR035W-A(locus name)|uniprotkb:VPS46(gene name synonym)|uniprotkb:Charged multivesicular body protein 1(gene name synonym)|uniprotkb:DOA4-independent degradation protein 2(gene name synonym)|uniprotkb:DID2(gene name)|psi-mi:DID2(display_short) psi-mi:did2_yeast(display_long)|uniprotkb:CHM1(gene name synonym)|uniprotkb:FTI1(gene name synonym)|uniprotkb:Fifty two inhibitor 1(gene name synonym)|uniprotkb:YKR035W-A(locus name)|uniprotkb:VPS46(gene name synonym)|uniprotkb:Charged multivesicular body protein 1(gene name synonym)|uniprotkb:DOA4-independent degradation protein 2(gene name synonym)|uniprotkb:DID2(gene name)|psi-mi:DID2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339682|imex:IM-14275-2341 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006435|refseq:NP_012961.3|dip:DIP-52223N|mint:P69771|ensemblfungi:YKR035W-A(gene)|ensemblfungi:YKR035W-A_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|rcsb pdb:3GGZ|rcsb pdb:5H7P sgd:S000006435|refseq:NP_012961.3|dip:DIP-52223N|mint:P69771|ensemblfungi:YKR035W-A(gene)|ensemblfungi:YKR035W-A_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|rcsb pdb:3GGZ|rcsb pdb:5H7P psi-mi:"MI:0469"(intact) crc64:70D1CF4588A8C6E6 crc64:70D1CF4588A8C6E6 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SVI1+8lRI6qwD0CSLY11Xq0LG0o559292 rogid:SVI1+8lRI6qwD0CSLY11Xq0LG0o559292 intact-crc:A1B5CEC62CF8B66C|rigid:kaeAeFZa2/ugUu6FdZdes/T9Uws false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07418 uniprotkb:P80667 intact:EBI-292|uniprotkb:D6VRT2|ensemblfungi:YDL065C intact:EBI-13206|ensemblfungi:YLR191W|uniprotkb:D6VYJ4 psi-mi:pex19_yeast(display_long)|uniprotkb:PEX19(gene name)|psi-mi:PEX19(display_short)|uniprotkb:PAS12(gene name synonym)|uniprotkb:YDL065C(locus name)|uniprotkb:Peroxin-19(gene name synonym)|uniprotkb:D2528(orf name) psi-mi:pex13_yeast(display_long)|uniprotkb:PEX13(gene name)|psi-mi:PEX13(display_short)|uniprotkb:PAS20(gene name synonym)|uniprotkb:YLR191W(locus name)|uniprotkb:L9470.1(orf name)|uniprotkb:Peroxin-13(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339693|imex:IM-14275-2342 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010218.2|sgd:S000002223|dip:DIP-1563N|mint:Q07418|ensemblfungi:YDL065C(gene)|ensemblfungi:YDL065C_mRNA(transcript)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0033328"(peroxisome membrane targeting sequence binding)|go:"GO:0045033"(peroxisome inheritance)|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0050821"(protein stabilization)|go:"GO:1990415"|interpro:IPR006708(Pex19 protein)|interpro:IPR038322|reactome:R-SCE-1369062|reactome:R-SCE-9603798 refseq:NP_013292.1|sgd:S000004181|ensemblfungi:YLR191W(gene)|ensemblfungi:YLR191W_mRNA(transcript)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:1990415"|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|interpro:IPR035463|interpro:IPR036028|rcsb pdb:1JQQ|rcsb pdb:1N5Z|rcsb pdb:1NM7|rcsb pdb:2V1R|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-9603798|mint:P80667|dip:DIP-2473N psi-mi:"MI:0469"(intact) crc64:B2FDE24970443D2A crc64:DBEA9A2372185860 figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:u/Q3DGHpQR712xEWNu1B/m5V72I559292 rogid:vt02VeRiVrVNk3HkjG1GPEcvPSU559292 intact-crc:9799385EEC3E9F6F|rigid:cYKjXfkfHq59/B0v52OzNEKtwNc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P80667 uniprotkb:Q12462 intact:EBI-13206|ensemblfungi:YLR191W|uniprotkb:D6VYJ4 intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C psi-mi:pex13_yeast(display_long)|uniprotkb:PEX13(gene name)|psi-mi:PEX13(display_short)|uniprotkb:PAS20(gene name synonym)|uniprotkb:YLR191W(locus name)|uniprotkb:L9470.1(orf name)|uniprotkb:Peroxin-13(gene name synonym) psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339704|imex:IM-14275-2343 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013292.1|sgd:S000004181|ensemblfungi:YLR191W(gene)|ensemblfungi:YLR191W_mRNA(transcript)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:1990415"|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|interpro:IPR035463|interpro:IPR036028|rcsb pdb:1JQQ|rcsb pdb:1N5Z|rcsb pdb:1NM7|rcsb pdb:2V1R|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-9603798|mint:P80667|dip:DIP-2473N refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) psi-mi:"MI:0469"(intact) crc64:DBEA9A2372185860 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vt02VeRiVrVNk3HkjG1GPEcvPSU559292 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 intact-crc:131224127033A96E|rigid:gWw9M2+zH/Kmt0dEPknf0hcuUtI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12465 uniprotkb:Q00402 intact:EBI-35494|uniprotkb:D6VY84|ensemblfungi:YLR084C intact:EBI-12386|uniprotkb:Q03767|ensemblfungi:YDR150W|uniprotkb:D6VSD2 psi-mi:rax2_yeast(display_long)|uniprotkb:RAX2(gene name)|psi-mi:RAX2(display_short)|uniprotkb:YLR084C(locus name)|uniprotkb:Revert to axial protein 2(gene name synonym)|uniprotkb:L2389(orf name)|uniprotkb:L9449.12(orf name) psi-mi:num1_yeast(display_long)|uniprotkb:NUM1(gene name)|psi-mi:NUM1(display_short)|uniprotkb:YDR150W(locus name)|uniprotkb:PAC12(gene name synonym)|uniprotkb:YD8358.06(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339715|imex:IM-14275-2344 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013185.1|sgd:S000004074|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|mint:Q12465|ensemblfungi:YLR084C(gene)|ensemblfungi:YLR084C_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0005621"(cellular bud scar)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007120"(axial cellular bud site selection)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0061161"(positive regulation of establishment of bipolar cell polarity regulating cell shape)|go:"GO:1902929"(plasma membrane of growing cell tip) ensemblfungi:YDR150W(gene)|ensemblfungi:YDR150W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005938"(cell cortex)|go:"GO:0015631"(tubulin binding)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0030989"(dynein-driven meiotic oscillatory nuclear movement)|go:"GO:0032065"(maintenance of protein location in cell cortex)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR001849(Pleckstrin-like)|go:"GO:0005543"(phospholipid binding)|interpro:IPR024774|refseq:NP_010434.1|sgd:S000002557|mint:Q00402|dip:DIP-3018N psi-mi:"MI:0469"(intact) - crc64:EB4E48F950621142 figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MOXpcwpgQ/Yv6NvIBn9V+CjBlAg559292 rogid:w/ctanEMAfvghFO7lBjXuApb6a8559292 intact-crc:DD759D733C36A40D|rigid:gFsgL9isQ25J36KggvYRlsQwTsQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00578 uniprotkb:P11986 intact:EBI-14683|uniprotkb:D6VVE4|ensemblfungi:YIL143C intact:EBI-9257|ensemblfungi:YJL153C|uniprotkb:D6VW34 psi-mi:rad25_yeast(display_long)|uniprotkb:YIL143C(locus name)|uniprotkb:SSL2(gene name)|psi-mi:SSL2(display_short)|uniprotkb:RAD25(gene name synonym)|uniprotkb:UVS112(gene name synonym)|uniprotkb:LOM3(gene name synonym)|uniprotkb:Suppressor of stem-loop mutation 2(gene name synonym)|uniprotkb:DNA repair helicase RAD25(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit SSL2(gene name synonym) psi-mi:ino1_yeast(display_long)|uniprotkb:INO1(gene name)|psi-mi:INO1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym)|uniprotkb:J0610(orf name)|uniprotkb:YJL153C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339726|imex:IM-14275-2345 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012123.1|sgd:S000001405|ensemblfungi:YIL143C(gene)|ensemblfungi:YIL143C_mRNA(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001111"(promoter clearance from RNA polymerase II promoter)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0005634"(nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001161("Xeroderma pigmentosum group B protein (XP-B)")|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032438|interpro:IPR032830|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|dip:DIP-731N|mint:Q00578 rcsb pdb:1P1K|ensemblfungi:YJL153C(gene)|ensemblfungi:YJL153C_mRNA(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|rcsb pdb:1JKF|rcsb pdb:1JKI|rcsb pdb:1LA2|rcsb pdb:1P1F|rcsb pdb:1P1H|rcsb pdb:1P1I|rcsb pdb:1P1J|rcsb pdb:1RM0|reactome:R-SCE-1855183|refseq:NP_012382.2|sgd:S000003689|dip:DIP-5687N|mint:P11986 psi-mi:"MI:0469"(intact) crc64:FA4013E8156FE1C5 crc64:282E2AE5D156289D figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YtV99gfzqhICf6nFYLAhh3Kg0C0559292 rogid:3OB3q28fOVxXSBMwMpLe2c1g8p8559292 intact-crc:B9E1748AE8BFD9C4|rigid:Gf20PJX54zW0AqQgSve8Qs8H600 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00578 uniprotkb:P16965 intact:EBI-14683|uniprotkb:D6VVE4|ensemblfungi:YIL143C intact:EBI-2045666|uniprotkb:D6VUE5|uniprotkb:P89099|ensemblfungi:YGR008C psi-mi:rad25_yeast(display_long)|uniprotkb:YIL143C(locus name)|uniprotkb:SSL2(gene name)|psi-mi:SSL2(display_short)|uniprotkb:RAD25(gene name synonym)|uniprotkb:UVS112(gene name synonym)|uniprotkb:LOM3(gene name synonym)|uniprotkb:Suppressor of stem-loop mutation 2(gene name synonym)|uniprotkb:DNA repair helicase RAD25(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit SSL2(gene name synonym) psi-mi:stf2_yeast(display_long)|uniprotkb:G3858(orf name)|uniprotkb:YGR008C(locus name)|uniprotkb:STF2(gene name)|psi-mi:STF2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339737|imex:IM-14275-2346 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012123.1|sgd:S000001405|ensemblfungi:YIL143C(gene)|ensemblfungi:YIL143C_mRNA(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001111"(promoter clearance from RNA polymerase II promoter)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0005634"(nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001161("Xeroderma pigmentosum group B protein (XP-B)")|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032438|interpro:IPR032830|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|dip:DIP-731N|mint:Q00578 refseq:NP_011522.1|sgd:S000003240|mint:P16965|ensemblfungi:YGR008C(gene)|ensemblfungi:YGR008C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0071465"(cellular response to desiccation) psi-mi:"MI:0469"(intact) crc64:FA4013E8156FE1C5 - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YtV99gfzqhICf6nFYLAhh3Kg0C0559292 rogid:Jg0WHw2YG9JnO2ke+FnQjnchklE559292 intact-crc:2358ACB01971B7A3|rigid:lPata7LwgT7mT8vQTm/0m4F7KaQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00578 uniprotkb:P37012 intact:EBI-14683|uniprotkb:D6VVE4|ensemblfungi:YIL143C intact:EBI-13296|uniprotkb:D6VZS7|ensemblfungi:YMR105C psi-mi:rad25_yeast(display_long)|uniprotkb:YIL143C(locus name)|uniprotkb:SSL2(gene name)|psi-mi:SSL2(display_short)|uniprotkb:RAD25(gene name synonym)|uniprotkb:UVS112(gene name synonym)|uniprotkb:LOM3(gene name synonym)|uniprotkb:Suppressor of stem-loop mutation 2(gene name synonym)|uniprotkb:DNA repair helicase RAD25(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit SSL2(gene name synonym) psi-mi:pgm2_yeast(display_long)|uniprotkb:PGM2(gene name)|psi-mi:PGM2(display_short)|uniprotkb:GAL5(gene name synonym)|uniprotkb:YMR105C(locus name)|uniprotkb:YM9718.04C(orf name)|uniprotkb:Glucose phosphomutase 2(gene name synonym)|uniprotkb:"D-glucose-1,6-diphosphate:D-glucose-1-phosphate phosphotransferase"(gene name synonym)|uniprotkb:GA-5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339748|imex:IM-14275-2347 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012123.1|sgd:S000001405|ensemblfungi:YIL143C(gene)|ensemblfungi:YIL143C_mRNA(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001111"(promoter clearance from RNA polymerase II promoter)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0005634"(nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001161("Xeroderma pigmentosum group B protein (XP-B)")|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032438|interpro:IPR032830|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|dip:DIP-731N|mint:Q00578 refseq:NP_013823.1|sgd:S000004711|mint:P37012|dip:DIP-6499N|ensemblfungi:YMR105C(gene)|ensemblfungi:YMR105C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004614"(phosphoglucomutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019255"(glucose 1-phosphate metabolic process)|go:"GO:0019388"(galactose catabolic process)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR036900 psi-mi:"MI:0469"(intact) crc64:FA4013E8156FE1C5 crc64:45B78AFF8197645E figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YtV99gfzqhICf6nFYLAhh3Kg0C0559292 rogid:miT4vpKTbsa/OfXIppW6h1+TbPs559292 intact-crc:E3618300FE2E40A5|rigid:VgZVJtz/FQ17KkeIqg04VbZ7yNI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00578 uniprotkb:P38328 intact:EBI-14683|uniprotkb:D6VVE4|ensemblfungi:YIL143C intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C psi-mi:rad25_yeast(display_long)|uniprotkb:YIL143C(locus name)|uniprotkb:SSL2(gene name)|psi-mi:SSL2(display_short)|uniprotkb:RAD25(gene name synonym)|uniprotkb:UVS112(gene name synonym)|uniprotkb:LOM3(gene name synonym)|uniprotkb:Suppressor of stem-loop mutation 2(gene name synonym)|uniprotkb:DNA repair helicase RAD25(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit SSL2(gene name synonym) psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339759|imex:IM-14275-2348 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012123.1|sgd:S000001405|ensemblfungi:YIL143C(gene)|ensemblfungi:YIL143C_mRNA(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001111"(promoter clearance from RNA polymerase II promoter)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0005634"(nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001161("Xeroderma pigmentosum group B protein (XP-B)")|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032438|interpro:IPR032830|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|dip:DIP-731N|mint:Q00578 sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:FA4013E8156FE1C5 crc64:D75C6BB8EC35EEDF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YtV99gfzqhICf6nFYLAhh3Kg0C0559292 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 intact-crc:55FE00736AFBC5CA|rigid:iVoL8MgfTsljmMzqhYatO2QR6jU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00578 uniprotkb:P41811 intact:EBI-14683|uniprotkb:D6VVE4|ensemblfungi:YIL143C intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:rad25_yeast(display_long)|uniprotkb:YIL143C(locus name)|uniprotkb:SSL2(gene name)|psi-mi:SSL2(display_short)|uniprotkb:RAD25(gene name synonym)|uniprotkb:UVS112(gene name synonym)|uniprotkb:LOM3(gene name synonym)|uniprotkb:Suppressor of stem-loop mutation 2(gene name synonym)|uniprotkb:DNA repair helicase RAD25(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit SSL2(gene name synonym) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339770|imex:IM-14275-2349 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012123.1|sgd:S000001405|ensemblfungi:YIL143C(gene)|ensemblfungi:YIL143C_mRNA(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001111"(promoter clearance from RNA polymerase II promoter)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0005634"(nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001161("Xeroderma pigmentosum group B protein (XP-B)")|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032438|interpro:IPR032830|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|dip:DIP-731N|mint:Q00578 refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:FA4013E8156FE1C5 crc64:6A5E50BBEB02CB58 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YtV99gfzqhICf6nFYLAhh3Kg0C0559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:652244D716A1183F|rigid:vT5OToJGl9gAqsnOb3gQvAUFmDE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00578 uniprotkb:P54113 intact:EBI-14683|uniprotkb:D6VVE4|ensemblfungi:YIL143C intact:EBI-14213|uniprotkb:E9PAG6|ensemblfungi:YLR028C|uniprotkb:D6VY30 psi-mi:rad25_yeast(display_long)|uniprotkb:YIL143C(locus name)|uniprotkb:SSL2(gene name)|psi-mi:SSL2(display_short)|uniprotkb:RAD25(gene name synonym)|uniprotkb:UVS112(gene name synonym)|uniprotkb:LOM3(gene name synonym)|uniprotkb:Suppressor of stem-loop mutation 2(gene name synonym)|uniprotkb:DNA repair helicase RAD25(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit SSL2(gene name synonym) psi-mi:pur91_yeast(display_long)|uniprotkb:ADE16(gene name)|psi-mi:ADE16(display_short)|uniprotkb:YLR028C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339781|imex:IM-14275-2350 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012123.1|sgd:S000001405|ensemblfungi:YIL143C(gene)|ensemblfungi:YIL143C_mRNA(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001111"(promoter clearance from RNA polymerase II promoter)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0005634"(nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001161("Xeroderma pigmentosum group B protein (XP-B)")|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032438|interpro:IPR032830|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|dip:DIP-731N|mint:Q00578 mint:P54113|refseq:NP_013128.1|sgd:S000004018|ensemblfungi:YLR028C(gene)|ensemblfungi:YLR028C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|interpro:IPR036914|dip:DIP-4657N psi-mi:"MI:0469"(intact) crc64:FA4013E8156FE1C5 - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YtV99gfzqhICf6nFYLAhh3Kg0C0559292 rogid:SbZvY+c2tg098pE/sezKQp+3cFE559292 intact-crc:2B0300640D736842|rigid:GPmZjkEBjydaG7Z+PH53/6SHSJk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54783 uniprotkb:Q00578 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 intact:EBI-14683|uniprotkb:D6VVE4|ensemblfungi:YIL143C psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:rad25_yeast(display_long)|uniprotkb:YIL143C(locus name)|uniprotkb:SSL2(gene name)|psi-mi:SSL2(display_short)|uniprotkb:RAD25(gene name synonym)|uniprotkb:UVS112(gene name synonym)|uniprotkb:LOM3(gene name synonym)|uniprotkb:Suppressor of stem-loop mutation 2(gene name synonym)|uniprotkb:DNA repair helicase RAD25(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit SSL2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339792|imex:IM-14275-2351 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 refseq:NP_012123.1|sgd:S000001405|ensemblfungi:YIL143C(gene)|ensemblfungi:YIL143C_mRNA(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001111"(promoter clearance from RNA polymerase II promoter)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0005634"(nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001161("Xeroderma pigmentosum group B protein (XP-B)")|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032438|interpro:IPR032830|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|dip:DIP-731N|mint:Q00578 psi-mi:"MI:0469"(intact) - crc64:FA4013E8156FE1C5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 rogid:YtV99gfzqhICf6nFYLAhh3Kg0C0559292 intact-crc:290944B42C3E520D|rigid:r9/fuDK7NXly12NsOJHl4kBW7XQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32610 uniprotkb:Q00582 intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W intact:EBI-7954|uniprotkb:D6W0G3|ensemblfungi:YML121W psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym) psi-mi:gtr1_yeast(display_long)|uniprotkb:YM7056.05(orf name)|uniprotkb:YML121W(locus name)|uniprotkb:GTR1(gene name)|psi-mi:GTR1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339803|imex:IM-14275-2352 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610 refseq:NP_013585.1|sgd:S000004590|mint:Q00582|dip:DIP-1358N|ensemblfungi:YML121W(gene)|ensemblfungi:YML121W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006348"|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039397|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 psi-mi:"MI:0469"(intact) crc64:FDE93E1FAF0AEC5B crc64:B79CE7FE7AD2FDBE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292 rogid:5LJU5zMF4NDDY9Bmndu0Q+JIm54559292 intact-crc:33DCE8892B7AC81B|rigid:soKKV2qGwYOaxDvB8CyKAeIKFBs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00582 uniprotkb:P38247 intact:EBI-7954|uniprotkb:D6W0G3|ensemblfungi:YML121W intact:EBI-21507|uniprotkb:D6VQ76|ensemblfungi:YBR077C psi-mi:gtr1_yeast(display_long)|uniprotkb:YM7056.05(orf name)|uniprotkb:YML121W(locus name)|uniprotkb:GTR1(gene name)|psi-mi:GTR1(display_short) psi-mi:slm4_yeast(display_long)|uniprotkb:YBR077C(locus name)|uniprotkb:YBR0723(orf name)|uniprotkb:GSE complex subunit 1(gene name synonym)|uniprotkb:EGO complex subunit 3(gene name synonym)|uniprotkb:SLM4(gene name)|psi-mi:SLM4(display_short)|uniprotkb:EGO3(gene name synonym)|uniprotkb:GSE1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339814|imex:IM-14275-2353 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013585.1|sgd:S000004590|mint:Q00582|dip:DIP-1358N|ensemblfungi:YML121W(gene)|ensemblfungi:YML121W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006348"|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039397|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 refseq:NP_009633.3|sgd:S000000281|mint:P38247|dip:DIP-1763N|ensemblfungi:YBR077C(gene)|ensemblfungi:YBR077C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0071986"(Ragulator complex)|interpro:IPR020233|rcsb pdb:3LGO|rcsb pdb:4FTX|rcsb pdb:4FUW|rcsb pdb:4XPM|rcsb pdb:6JWP psi-mi:"MI:0469"(intact) crc64:B79CE7FE7AD2FDBE crc64:D64ABDE1CDF265FD figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5LJU5zMF4NDDY9Bmndu0Q+JIm54559292 rogid:BCEWjA3PQvwm3n08QwY0D//TpbA559292 intact-crc:298EC95C0F4C475B|rigid:5Uz2fclUqECnT3JNoK8c5THRvFg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00582 uniprotkb:P39968 intact:EBI-7954|uniprotkb:D6W0G3|ensemblfungi:YML121W intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W psi-mi:gtr1_yeast(display_long)|uniprotkb:YM7056.05(orf name)|uniprotkb:YML121W(locus name)|uniprotkb:GTR1(gene name)|psi-mi:GTR1(display_short) psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339825|imex:IM-14275-2354 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013585.1|sgd:S000004590|mint:Q00582|dip:DIP-1358N|ensemblfungi:YML121W(gene)|ensemblfungi:YML121W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006348"|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039397|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N psi-mi:"MI:0469"(intact) crc64:B79CE7FE7AD2FDBE crc64:B2E75774B47E5933 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5LJU5zMF4NDDY9Bmndu0Q+JIm54559292 rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292 intact-crc:E1F88D07DFBE974E|rigid:SgzleXUY9fbB7o5AHP6WKesgMGg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00582 uniprotkb:P53191 intact:EBI-7954|uniprotkb:D6W0G3|ensemblfungi:YML121W intact:EBI-13400|uniprotkb:E9P8Z2|uniprotkb:D6VUB4|ensemblfungi:YGL023C psi-mi:gtr1_yeast(display_long)|uniprotkb:YM7056.05(orf name)|uniprotkb:YML121W(locus name)|uniprotkb:GTR1(gene name)|psi-mi:GTR1(display_short) psi-mi:pib2_yeast(display_long)|uniprotkb:PIB2(gene name)|psi-mi:PIB2(display_short)|uniprotkb:YGL023C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339836|imex:IM-14275-2355 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013585.1|sgd:S000004590|mint:Q00582|dip:DIP-1358N|ensemblfungi:YML121W(gene)|ensemblfungi:YML121W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006348"|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039397|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 refseq:NP_011492.3|sgd:S000002991|ensemblfungi:YGL023C(gene)|ensemblfungi:YGL023C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|mint:P53191|dip:DIP-6378N psi-mi:"MI:0469"(intact) crc64:B79CE7FE7AD2FDBE crc64:512E9B873E6E0164 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5LJU5zMF4NDDY9Bmndu0Q+JIm54559292 rogid:3T1+dWkNV7dfKQf0/9hJkjQbRW4559292 intact-crc:0D2A268FF5F7AA51|rigid:UPNzutr3/R8/Jd8zldv3Ve6P9a4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00582 uniprotkb:Q00582 intact:EBI-7954|uniprotkb:D6W0G3|ensemblfungi:YML121W intact:EBI-7954|uniprotkb:D6W0G3|ensemblfungi:YML121W psi-mi:gtr1_yeast(display_long)|uniprotkb:YM7056.05(orf name)|uniprotkb:YML121W(locus name)|uniprotkb:GTR1(gene name)|psi-mi:GTR1(display_short) psi-mi:gtr1_yeast(display_long)|uniprotkb:YM7056.05(orf name)|uniprotkb:YML121W(locus name)|uniprotkb:GTR1(gene name)|psi-mi:GTR1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339847|imex:IM-14275-2356 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013585.1|sgd:S000004590|mint:Q00582|dip:DIP-1358N|ensemblfungi:YML121W(gene)|ensemblfungi:YML121W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006348"|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039397|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 refseq:NP_013585.1|sgd:S000004590|mint:Q00582|dip:DIP-1358N|ensemblfungi:YML121W(gene)|ensemblfungi:YML121W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006348"|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039397|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 psi-mi:"MI:0469"(intact) crc64:B79CE7FE7AD2FDBE crc64:B79CE7FE7AD2FDBE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5LJU5zMF4NDDY9Bmndu0Q+JIm54559292 rogid:5LJU5zMF4NDDY9Bmndu0Q+JIm54559292 intact-crc:0A41D1B522DEB7B6|rigid:KjSw0W1AN3DYfR8cXCDDj2wlcYY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00582 uniprotkb:Q02205 intact:EBI-7954|uniprotkb:D6W0G3|ensemblfungi:YML121W intact:EBI-27062|uniprotkb:D6VX73|ensemblfungi:YKR007W psi-mi:gtr1_yeast(display_long)|uniprotkb:YM7056.05(orf name)|uniprotkb:YML121W(locus name)|uniprotkb:GTR1(gene name)|psi-mi:GTR1(display_short) psi-mi:meh1_yeast(display_long)|uniprotkb:GSE complex subunit 2(gene name synonym)|uniprotkb:EGO complex subunit 1(gene name synonym)|uniprotkb:YKR007W(locus name)|uniprotkb:YK106(orf name)|uniprotkb:MEH1(gene name)|psi-mi:MEH1(display_short)|uniprotkb:EGO1(gene name synonym)|uniprotkb:GSE2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339858|imex:IM-14275-2357 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013585.1|sgd:S000004590|mint:Q00582|dip:DIP-1358N|ensemblfungi:YML121W(gene)|ensemblfungi:YML121W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006348"|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039397|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 sgd:S000001715|refseq:NP_012932.1|mint:Q02205|dip:DIP-1922N|ensemblfungi:YKR007W(gene)|ensemblfungi:YKR007W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0005829"(cytosol)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007040"(lysosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR028209|rcsb pdb:4XPM|rcsb pdb:6JWP psi-mi:"MI:0469"(intact) crc64:B79CE7FE7AD2FDBE crc64:995DD1E68331D050 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5LJU5zMF4NDDY9Bmndu0Q+JIm54559292 rogid:73a6e5W5wQixGg2aGXDo4A6NR2s559292 intact-crc:1D5B148EA9D83B6C|rigid:gMYfN2LbFKlgWBqYRyKr/v+zmzU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36000 uniprotkb:Q00776 intact:EBI-2206|uniprotkb:D6VX61|ensemblfungi:YKL135C intact:EBI-2624|uniprotkb:D6W3B0|ensemblfungi:YPL259C psi-mi:ap1b1_yeast(display_long)|uniprotkb:APL2(gene name)|psi-mi:APL2(display_short)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta-1 large chain(gene name synonym)|uniprotkb:Clathrin assembly protein large beta-1 chain(gene name synonym)|uniprotkb:YKL135C(locus name) psi-mi:ap1m1_yeast(display_long)|uniprotkb:APM1(gene name)|psi-mi:APM1(display_short)|uniprotkb:YAP54(gene name synonym)|uniprotkb:YPL259C(locus name)|uniprotkb:P0394(orf name)|uniprotkb:Mu1-I-adaptin(gene name synonym)|uniprotkb:"Mu(1)-adaptin"(gene name synonym)|uniprotkb:Golgi adaptor AP-1 54 kDa protein(gene name synonym)|uniprotkb:HA1 54 kDa subunit(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP54(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP54(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 mu-1-I medium chain(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339869|imex:IM-14275-2358 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012787.1|sgd:S000001618|dip:DIP-1199N|mint:P36000|ensemblfungi:YKL135C(gene)|ensemblfungi:YKL135C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030121"(AP-1 adaptor complex)|go:"GO:0030276"(clathrin binding)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|reactome:R-SCE-432720|reactome:R-SCE-437239|reactome:R-SCE-8856825|reactome:R-SCE-8856828|reactome:R-SCE-8866427|reactome:R-SCE-8964038 refseq:NP_015064.1|sgd:S000006180|dip:DIP-1198N|mint:Q00776|ensemblfungi:YPL259C(gene)|ensemblfungi:YPL259C_mRNA(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030121"(AP-1 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|reactome:R-SCE-432720|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) crc64:89893945D4EC6C4A crc64:C6B11153B845921C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MKH8RySJV469TEWyuJCOuAitkJY559292 rogid:i+bg9eNIcUTBkm2e24EczcfL7AQ559292 intact-crc:F100678F6D9771B1|rigid:qjBgU4aIEkFJMjCauY98YkU+yys false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01080 uniprotkb:Q01080 intact:EBI-15741|uniprotkb:D6W0U5|ensemblfungi:YNL248C intact:EBI-15741|uniprotkb:D6W0U5|ensemblfungi:YNL248C psi-mi:rpa49_yeast(display_long)|uniprotkb:RPA49(gene name)|psi-mi:RPA49(display_short)|uniprotkb:RRN13(gene name synonym)|uniprotkb:YNL248C(locus name)|uniprotkb:N0880(orf name)|uniprotkb:DNA-directed RNA polymerase I 49 kDa polypeptide(gene name synonym) psi-mi:rpa49_yeast(display_long)|uniprotkb:RPA49(gene name)|psi-mi:RPA49(display_short)|uniprotkb:RRN13(gene name synonym)|uniprotkb:YNL248C(locus name)|uniprotkb:N0880(orf name)|uniprotkb:DNA-directed RNA polymerase I 49 kDa polypeptide(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339880|imex:IM-14275-2359 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014151.1|sgd:S000005192|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0008361"(regulation of cell size)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR009668(RNA polymerase I associated factor, A49-like)|rcsb pdb:3NFH|rcsb pdb:3NFI|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|ensemblfungi:YNL248C(gene)|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|ensemblfungi:YNL248C_mRNA(transcript)|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|go:"GO:0001054"(RNA polymerase I activity)|rcsb pdb:6H67|rcsb pdb:6H68|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|rcsb pdb:6HKO|rcsb pdb:6RQH|dip:DIP-6577N|mint:Q01080 refseq:NP_014151.1|sgd:S000005192|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0008361"(regulation of cell size)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR009668(RNA polymerase I associated factor, A49-like)|rcsb pdb:3NFH|rcsb pdb:3NFI|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|ensemblfungi:YNL248C(gene)|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|ensemblfungi:YNL248C_mRNA(transcript)|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|go:"GO:0001054"(RNA polymerase I activity)|rcsb pdb:6H67|rcsb pdb:6H68|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|rcsb pdb:6HKO|rcsb pdb:6RQH|dip:DIP-6577N|mint:Q01080 psi-mi:"MI:0469"(intact) crc64:3D9BF05440D26021 crc64:3D9BF05440D26021 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:B7Nabi651A5fAilRf/0F2GHps/U559292 rogid:B7Nabi651A5fAilRf/0F2GHps/U559292 intact-crc:F234BD938D66E3B9|rigid:WjqovXXlWH2CbXtsaazb2JtD8FA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20447 uniprotkb:Q01448 intact:EBI-5608|uniprotkb:D6VU66|ensemblfungi:YGL078C intact:EBI-8520|uniprotkb:A2TBP6|uniprotkb:D6VQL1|ensemblfungi:YBR215W psi-mi:dbp3_yeast(display_long)|uniprotkb:YGL078C(locus name)|uniprotkb:DBP3(gene name)|psi-mi:DBP3(display_short)|uniprotkb:DEAD box protein 3(gene name synonym)|uniprotkb:Helicase CA3(gene name synonym) psi-mi:hpc2_yeast(display_long)|uniprotkb:YBR1503(orf name)|uniprotkb:YBR215W(locus name)|uniprotkb:HPC2(gene name)|psi-mi:HPC2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339891|imex:IM-14275-2360 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003046|refseq:NP_011437.3|dip:DIP-2668N|mint:P20447|ensemblfungi:YGL078C(gene)|ensemblfungi:YGL078C_mRNA(transcript)|go:"GO:0000464"("endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417 sgd:S000000419|refseq:NP_009774.4|mint:Q01448|dip:DIP-4587N|ensemblfungi:YBR215W(gene)|ensemblfungi:YBR215W_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000417"(HIR complex)|go:"GO:0005634"(nucleus)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|interpro:IPR014840("Histone promoter control 2 (HPC2)")|reactome:R-SCE-2559584 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9ltHUfhcU8nfN3bxsmkabo8A2L4559292 rogid:CsJSA6+yuGVBb5X9gZH7YhnzH0E559292 intact-crc:027303451038D3F5|rigid:bFBa/pFfYTA2uC/GmdoAz1hH8ss false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01574 uniprotkb:P80235 intact:EBI-2128|uniprotkb:Q66RJ0|uniprotkb:D6VPG4|ensemblfungi:YAL054C intact:EBI-3928|uniprotkb:D6VPN4|ensemblfungi:YAR035W psi-mi:acs1_yeast(display_long)|uniprotkb:ACS1(gene name)|psi-mi:ACS1(display_short)|uniprotkb:YAL054C(locus name)|uniprotkb:FUN44(orf name)|uniprotkb:Acetate--CoA ligase 1(gene name synonym)|uniprotkb:Acyl-activating enzyme 1(gene name synonym) psi-mi:cacm_yeast(display_long)|uniprotkb:YAT1(gene name)|psi-mi:YAT1(display_short)|uniprotkb:YAR035W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339902|imex:IM-14275-2361 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009347.1|sgd:S000000050|dip:DIP-4326N|mint:Q01574|ensemblfungi:YAL054C(gene)|ensemblfungi:YAL054C_mRNA(transcript)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0016208"(AMP binding)|go:"GO:0016573"(histone acetylation)|go:"GO:0016880"("acid-ammonia (or amide) ligase activity")|go:"GO:0019427"(acetyl-CoA biosynthetic process from acetate)|go:"GO:0019654"(acetate fermentation)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR011904(Acetate--CoA ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR032387|interpro:IPR042099|rcsb pdb:1RY2|reactome:R-SCE-71384 refseq:NP_009420.1|sgd:S000000080|dip:DIP-3795N|mint:P80235|ensemblfungi:YAR035W(gene)|ensemblfungi:YAR035W_mRNA(transcript)|go:"GO:0004092"(carnitine O-acetyltransferase activity)|go:"GO:0004095"(carnitine O-palmitoyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0009437"(carnitine metabolic process)|interpro:IPR000542(Acyltransferase ChoActase/COT/CPT)|interpro:IPR023213|interpro:IPR039551|interpro:IPR042231 psi-mi:"MI:0469"(intact) - crc64:F00B628893B8BB39 figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FCtLscpQF6B8K/xWKsz5w0S2PHc559292 rogid:+uZbvaZzpfeW1Rp1iJLBWEWlIHk559292 intact-crc:A739D9946769B263|rigid:aIBxow83Ab+UYfVSWgi54/Oo6A0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01896 uniprotkb:P36027 intact:EBI-2055692|uniprotkb:D6VS27|ensemblfungi:YDR039C intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:atn2_yeast(display_long)|uniprotkb:YDR039C(locus name)|uniprotkb:PMR2B(gene name synonym)|uniprotkb:ENA2(gene name)|psi-mi:ENA2(display_short) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339913|imex:IM-14275-2362 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002446|refseq:NP_010324.3|dip:DIP-7915N|mint:Q01896|ensemblfungi:YDR039C(gene)|ensemblfungi:YDR039C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0008554"(P-type sodium transporter activity)|go:"GO:0008556"(P-type potassium transmembrane transporter activity)|go:"GO:0015662"(P-type ion transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006414(Potassium/sodium efflux P-type ATPase, fungal-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492 ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1b49ORiqG6Pt3x/IwyIi4wBZW88559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:9C7D0B4B62BA2032|rigid:IDTPN/IBnHqLmfFqTzgKq6E5dk4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01896 uniprotkb:P38234 intact:EBI-2055692|uniprotkb:D6VS27|ensemblfungi:YDR039C intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C psi-mi:atn2_yeast(display_long)|uniprotkb:YDR039C(locus name)|uniprotkb:PMR2B(gene name synonym)|uniprotkb:ENA2(gene name)|psi-mi:ENA2(display_short) psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339924|imex:IM-14275-2363 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002446|refseq:NP_010324.3|dip:DIP-7915N|mint:Q01896|ensemblfungi:YDR039C(gene)|ensemblfungi:YDR039C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0008554"(P-type sodium transporter activity)|go:"GO:0008556"(P-type potassium transmembrane transporter activity)|go:"GO:0015662"(P-type ion transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006414(Potassium/sodium efflux P-type ATPase, fungal-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492 refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1b49ORiqG6Pt3x/IwyIi4wBZW88559292 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 intact-crc:7E3E5268A184B5FB|rigid:9o/noGyNuyBB0o0W0YbwOEpXOVw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01896 uniprotkb:Q02785 intact:EBI-2055692|uniprotkb:D6VS27|ensemblfungi:YDR039C intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:atn2_yeast(display_long)|uniprotkb:YDR039C(locus name)|uniprotkb:PMR2B(gene name synonym)|uniprotkb:ENA2(gene name)|psi-mi:ENA2(display_short) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339935|imex:IM-14275-2364 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002446|refseq:NP_010324.3|dip:DIP-7915N|mint:Q01896|ensemblfungi:YDR039C(gene)|ensemblfungi:YDR039C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0008554"(P-type sodium transporter activity)|go:"GO:0008556"(P-type potassium transmembrane transporter activity)|go:"GO:0015662"(P-type ion transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006414(Potassium/sodium efflux P-type ATPase, fungal-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492 refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1b49ORiqG6Pt3x/IwyIi4wBZW88559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:C104FFF94E2194C5|rigid:tsDSjJ6xQyVkE/afXzhGeJkfxN8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01939 uniprotkb:P33297 intact:EBI-13914|ensemblfungi:YGL048C|uniprotkb:D6VU92 intact:EBI-13920|uniprotkb:D6W2H6|ensemblfungi:YOR117W psi-mi:prs8_yeast(display_long)|uniprotkb:TBPY(gene name synonym)|uniprotkb:TBY1(gene name synonym)|uniprotkb:YGL048C(locus name)|uniprotkb:RPT6(gene name)|psi-mi:RPT6(display_short)|uniprotkb:CIM3(gene name synonym)|uniprotkb:CRL3(gene name synonym)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Protein SUG1(gene name synonym)|uniprotkb:Protein CIM3(gene name synonym)|uniprotkb:Tat-binding protein TBY1(gene name synonym) psi-mi:prs6a_yeast(display_long)|uniprotkb:RPT5(gene name)|psi-mi:RPT5(display_short)|uniprotkb:YTA1(gene name synonym)|uniprotkb:YOR117W(locus name)|uniprotkb:O3258(orf name)|uniprotkb:YOR3258W(orf name)|uniprotkb:Tat-binding protein homolog 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339946|imex:IM-14275-2365 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-8854050|ensemblfungi:YGL048C(gene)|ensemblfungi:YGL048C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011467.1|sgd:S000003016|mint:Q01939|dip:DIP-979N sgd:S000005643|rcsb pdb:3WHL|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|rcsb pdb:3WHK|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|ensemblfungi:YOR117W(gene)|ensemblfungi:YOR117W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|refseq:NP_014760.3|mint:P33297|dip:DIP-1590N psi-mi:"MI:0469"(intact) crc64:9C59E92A0794F60F crc64:C215422033FCE830 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lvkwNLqTeoit17Ax4mP0+WiGzsY559292 rogid:jsQE3SjBA0ZZcysuLgFe/5M6pOc559292 intact-crc:F5F9169BEAB20C50|rigid:aelxxVFjit5loxb4Ng/+JgRsJz8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01939 uniprotkb:P33298 intact:EBI-13914|ensemblfungi:YGL048C|uniprotkb:D6VU92 intact:EBI-13905|ensemblfungi:YDR394W|uniprotkb:D6VT28 psi-mi:prs8_yeast(display_long)|uniprotkb:TBPY(gene name synonym)|uniprotkb:TBY1(gene name synonym)|uniprotkb:YGL048C(locus name)|uniprotkb:RPT6(gene name)|psi-mi:RPT6(display_short)|uniprotkb:CIM3(gene name synonym)|uniprotkb:CRL3(gene name synonym)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Protein SUG1(gene name synonym)|uniprotkb:Protein CIM3(gene name synonym)|uniprotkb:Tat-binding protein TBY1(gene name synonym) psi-mi:prs6b_yeast(display_long)|uniprotkb:RPT3(gene name)|psi-mi:RPT3(display_short)|uniprotkb:YNT1(gene name synonym)|uniprotkb:YTA2(gene name synonym)|uniprotkb:YDR394W(locus name)|uniprotkb:D9509.14(orf name)|uniprotkb:Protein YNT1(gene name synonym)|uniprotkb:Tat-binding homolog 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339957|imex:IM-14275-2366 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-8854050|ensemblfungi:YGL048C(gene)|ensemblfungi:YGL048C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011467.1|sgd:S000003016|mint:Q01939|dip:DIP-979N sgd:S000002802|ensemblfungi:YDR394W(gene)|ensemblfungi:YDR394W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|refseq:NP_010682.3|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|rcsb pdb:2DZN|rcsb pdb:2DZO|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33298|dip:DIP-1587N|interpro:IPR003960(AAA ATPase, conserved site) psi-mi:"MI:0469"(intact) crc64:9C59E92A0794F60F crc64:E12F0995A60732BD figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lvkwNLqTeoit17Ax4mP0+WiGzsY559292 rogid:teaQwAlS0ruTNKbLkX7kP4lkn7o559292 intact-crc:FAF916A13312078E|rigid:RDNMx3i6p0VSOqFq+CanzOtI1fw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01939 uniprotkb:P33299 intact:EBI-13914|ensemblfungi:YGL048C|uniprotkb:D6VU92 intact:EBI-13910|uniprotkb:D6VX51|ensemblfungi:YKL145W psi-mi:prs8_yeast(display_long)|uniprotkb:TBPY(gene name synonym)|uniprotkb:TBY1(gene name synonym)|uniprotkb:YGL048C(locus name)|uniprotkb:RPT6(gene name)|psi-mi:RPT6(display_short)|uniprotkb:CIM3(gene name synonym)|uniprotkb:CRL3(gene name synonym)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Protein SUG1(gene name synonym)|uniprotkb:Protein CIM3(gene name synonym)|uniprotkb:Tat-binding protein TBY1(gene name synonym) psi-mi:prs7_yeast(display_long)|uniprotkb:YKL145W(locus name)|uniprotkb:RPT1(gene name)|psi-mi:RPT1(display_short)|uniprotkb:CIM5(gene name synonym)|uniprotkb:YTA3(gene name synonym)|uniprotkb:Protein CIM5(gene name synonym)|uniprotkb:Tat-binding homolog 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339968|imex:IM-14275-2367 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-8854050|ensemblfungi:YGL048C(gene)|ensemblfungi:YGL048C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011467.1|sgd:S000003016|mint:Q01939|dip:DIP-979N refseq:NP_012777.1|sgd:S000001628|ensemblfungi:YKL145W(gene)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|ensemblfungi:YKL145W_mRNA(transcript)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0005524"(ATP binding)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|go:"GO:0005634"(nucleus)|rcsb pdb:3VLF|rcsb pdb:4A3V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4JPO|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|rcsb pdb:5A5B|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:5MP9|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|rcsb pdb:6EF3|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33299|dip:DIP-2883N psi-mi:"MI:0469"(intact) crc64:9C59E92A0794F60F crc64:8454BBC9D549EC5C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lvkwNLqTeoit17Ax4mP0+WiGzsY559292 rogid:8XXo53yZ1KevHObtYWABeFr0hWo559292 intact-crc:FBF916A58E6B9FCC|rigid:Eacn17PqGd75u1Gw9o/Eqcu1NHc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01939 uniprotkb:P40327 intact:EBI-13914|ensemblfungi:YGL048C|uniprotkb:D6VU92 intact:EBI-13901|uniprotkb:D6VRY1|ensemblfungi:YDL007W psi-mi:prs8_yeast(display_long)|uniprotkb:TBPY(gene name synonym)|uniprotkb:TBY1(gene name synonym)|uniprotkb:YGL048C(locus name)|uniprotkb:RPT6(gene name)|psi-mi:RPT6(display_short)|uniprotkb:CIM3(gene name synonym)|uniprotkb:CRL3(gene name synonym)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Protein SUG1(gene name synonym)|uniprotkb:Protein CIM3(gene name synonym)|uniprotkb:Tat-binding protein TBY1(gene name synonym) psi-mi:prs4_yeast(display_long)|uniprotkb:RPT2(gene name)|psi-mi:RPT2(display_short)|uniprotkb:YHS4(gene name synonym)|uniprotkb:YTA5(gene name synonym)|uniprotkb:YDL007W(locus name)|uniprotkb:D2920(orf name)|uniprotkb:Tat-binding homolog 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339979|imex:IM-14275-2368 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-8854050|ensemblfungi:YGL048C(gene)|ensemblfungi:YGL048C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011467.1|sgd:S000003016|mint:Q01939|dip:DIP-979N refseq:NP_010277.1|sgd:S000002165|ensemblfungi:YDL007W(gene)|ensemblfungi:YDL007W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0034629"|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:4CR2|rcsb pdb:3JCP|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-532668|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P40327|dip:DIP-6282N psi-mi:"MI:0469"(intact) crc64:9C59E92A0794F60F crc64:EB735354C3A0EBD4 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lvkwNLqTeoit17Ax4mP0+WiGzsY559292 rogid:nSy31Q+snoZMZrFmXscv8/HQYk0559292 intact-crc:698FBEB4E59AFA9B|rigid:8YbBSqmMv/Dy1CrrhC8r+0Urpgo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01939 uniprotkb:P53549 intact:EBI-13914|ensemblfungi:YGL048C|uniprotkb:D6VU92 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C psi-mi:prs8_yeast(display_long)|uniprotkb:TBPY(gene name synonym)|uniprotkb:TBY1(gene name synonym)|uniprotkb:YGL048C(locus name)|uniprotkb:RPT6(gene name)|psi-mi:RPT6(display_short)|uniprotkb:CIM3(gene name synonym)|uniprotkb:CRL3(gene name synonym)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Protein SUG1(gene name synonym)|uniprotkb:Protein CIM3(gene name synonym)|uniprotkb:Tat-binding protein TBY1(gene name synonym) psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6339990|imex:IM-14275-2369 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-8854050|ensemblfungi:YGL048C(gene)|ensemblfungi:YGL048C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011467.1|sgd:S000003016|mint:Q01939|dip:DIP-979N sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 psi-mi:"MI:0469"(intact) crc64:9C59E92A0794F60F crc64:0EA42A599E2B2E2A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lvkwNLqTeoit17Ax4mP0+WiGzsY559292 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 intact-crc:EB1437C6FBD7FE80|rigid:rnx5Qn3EDG3ELvaE5CurWmTgYUA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02046 uniprotkb:Q02046 intact:EBI-2045181|uniprotkb:D6VXE0|ensemblfungi:YKR080W intact:EBI-2045181|uniprotkb:D6VXE0|ensemblfungi:YKR080W psi-mi:mtd1_yeast(display_long)|uniprotkb:YKR400(orf name)|uniprotkb:YKR080W(locus name)|uniprotkb:MTD1(gene name)|psi-mi:MTD1(display_short) psi-mi:mtd1_yeast(display_long)|uniprotkb:YKR400(orf name)|uniprotkb:YKR080W(locus name)|uniprotkb:MTD1(gene name)|psi-mi:MTD1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340001|imex:IM-14275-2370 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001788|refseq:NP_013006.3|dip:DIP-730N|mint:Q02046|ensemblfungi:YKR080W(gene)|ensemblfungi:YKR080W_mRNA(transcript)|go:"GO:0004487"("methylenetetrahydrofolate dehydrogenase (NAD+) activity")|go:"GO:0004488"("methylenetetrahydrofolate dehydrogenase (NADP+) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0009396"(folic acid-containing compound biosynthetic process)|interpro:IPR000672(Tetrahydrofolate dehydrogenase/cyclohydrolase)|interpro:IPR020630|interpro:IPR020631|interpro:IPR035812|interpro:IPR036291|rcsb pdb:1EDZ|rcsb pdb:1EE9 sgd:S000001788|refseq:NP_013006.3|dip:DIP-730N|mint:Q02046|ensemblfungi:YKR080W(gene)|ensemblfungi:YKR080W_mRNA(transcript)|go:"GO:0004487"("methylenetetrahydrofolate dehydrogenase (NAD+) activity")|go:"GO:0004488"("methylenetetrahydrofolate dehydrogenase (NADP+) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0009396"(folic acid-containing compound biosynthetic process)|interpro:IPR000672(Tetrahydrofolate dehydrogenase/cyclohydrolase)|interpro:IPR020630|interpro:IPR020631|interpro:IPR035812|interpro:IPR036291|rcsb pdb:1EDZ|rcsb pdb:1EE9 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:xAOzw/g5xSBjpNJuVTxsxTeWAEI559292 rogid:xAOzw/g5xSBjpNJuVTxsxTeWAEI559292 intact-crc:9A6F696A8BF1494E|rigid:p9+sa1oCti8l88aeOeEo+X3/oYs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06411 uniprotkb:Q02100 intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W intact:EBI-17289|uniprotkb:D6W115|ensemblfungi:YNL167C psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym) psi-mi:sko1_yeast(display_long)|uniprotkb:SKO1(gene name)|psi-mi:SKO1(display_short)|uniprotkb:ACR1(gene name synonym)|uniprotkb:YNL167C(locus name)|uniprotkb:N1702(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340012|imex:IM-14275-2371 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88 refseq:NP_014232.1|sgd:S000005111|ensemblfungi:YNL167C(gene)|ensemblfungi:YNL167C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051019"(mitogen-activated protein kinase binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR020956|reactome:R-SCE-3214847|reactome:R-SCE-450341|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|dip:DIP-700N|mint:Q02100 psi-mi:"MI:0469"(intact) crc64:9986B547B9582338 - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292 rogid:IcQvyxqkshScg9aNFCq22YzqL90559292 intact-crc:06B25A9E91FEF215|rigid:F3u5htULup20lltiwA53NVa63G4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02199 uniprotkb:P14907 intact:EBI-12315|ensemblfungi:YGL172W|uniprotkb:D6VTY0 intact:EBI-12265|uniprotkb:D6VWE3 psi-mi:nup49_yeast(display_long)|uniprotkb:NUP49(gene name)|psi-mi:NUP49(display_short)|uniprotkb:NSP49(gene name synonym)|uniprotkb:YGL172W(locus name)|uniprotkb:G1648(orf name)|uniprotkb:Nuclear pore protein NUP49/NSP49(gene name synonym) psi-mi:nsp1_yeast(display_long)|uniprotkb:NSP1(gene name)|psi-mi:NSP1(display_short)|uniprotkb:YJL041W(locus name)|uniprotkb:J1207(orf name)|uniprotkb:Nuclear pore protein NSP1(gene name synonym)|uniprotkb:Nucleoskeletal-like protein(gene name synonym)|uniprotkb:p110(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340023|imex:IM-14275-2372 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011343.1|sgd:S000003140|ensemblfungi:YGL172W(gene)|ensemblfungi:YGL172W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR024864|interpro:IPR025574|interpro:IPR039079|mint:Q02199|dip:DIP-709N go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0097064"(ncRNA export from nucleus)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|rcsb pdb:1O6O|refseq:NP_012494.3|sgd:S000003577|mint:P14907|dip:DIP-1484N psi-mi:"MI:0469"(intact) - crc64:A258003CB1917810 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2x0Rt5ViHxBEKxPzOcfnyOdgmpg559292 rogid:wFdC6D8JzkhJpF+k3qtnFj9+4pA559292 intact-crc:49507805E68485F5|rigid:bSjncWf7U+k+hgRPhoz/hHrlZbo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02199 uniprotkb:P34077 intact:EBI-12315|ensemblfungi:YGL172W|uniprotkb:D6VTY0 intact:EBI-12056|ensemblfungi:YFR002W|uniprotkb:D6VTN2 psi-mi:nup49_yeast(display_long)|uniprotkb:NUP49(gene name)|psi-mi:NUP49(display_short)|uniprotkb:NSP49(gene name synonym)|uniprotkb:YGL172W(locus name)|uniprotkb:G1648(orf name)|uniprotkb:Nuclear pore protein NUP49/NSP49(gene name synonym) psi-mi:nic96_yeast(display_long)|uniprotkb:YFR002W(locus name)|uniprotkb:NIC96(gene name)|psi-mi:NIC96(display_short)|uniprotkb:Nuclear pore protein NIC96(gene name synonym)|uniprotkb:96 kDa nucleoporin-interacting component(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340034|imex:IM-14275-2373 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011343.1|sgd:S000003140|ensemblfungi:YGL172W(gene)|ensemblfungi:YGL172W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR024864|interpro:IPR025574|interpro:IPR039079|mint:Q02199|dip:DIP-709N ensemblfungi:YFR002W(gene)|ensemblfungi:YFR002W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044615"(nuclear pore nuclear basket)|interpro:IPR007231(Nucleoporin interacting component)|rcsb pdb:2RFO|rcsb pdb:6X07|rcsb pdb:2QX5|refseq:NP_116657.1|sgd:S000001898|mint:P34077|dip:DIP-745N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2x0Rt5ViHxBEKxPzOcfnyOdgmpg559292 rogid:gjcrAg3tofVODSE7T+SsoTVlesA559292 intact-crc:C398ECDB3B97BF80|rigid:yM8KYPvRVAZykbA6J9uWCizE+As false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48837 uniprotkb:Q02199 intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0 intact:EBI-12315|ensemblfungi:YGL172W|uniprotkb:D6VTY0 psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym) psi-mi:nup49_yeast(display_long)|uniprotkb:NUP49(gene name)|psi-mi:NUP49(display_short)|uniprotkb:NSP49(gene name synonym)|uniprotkb:YGL172W(locus name)|uniprotkb:G1648(orf name)|uniprotkb:Nuclear pore protein NUP49/NSP49(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340045|imex:IM-14275-2374 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N refseq:NP_011343.1|sgd:S000003140|ensemblfungi:YGL172W(gene)|ensemblfungi:YGL172W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR024864|interpro:IPR025574|interpro:IPR039079|mint:Q02199|dip:DIP-709N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292 rogid:2x0Rt5ViHxBEKxPzOcfnyOdgmpg559292 intact-crc:6F5ADADB0E47852C|rigid:vKpcan76b1yq6a7X0dk226qHI+U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02199 uniprotkb:Q02199 intact:EBI-12315|ensemblfungi:YGL172W|uniprotkb:D6VTY0 intact:EBI-12315|ensemblfungi:YGL172W|uniprotkb:D6VTY0 psi-mi:nup49_yeast(display_long)|uniprotkb:NUP49(gene name)|psi-mi:NUP49(display_short)|uniprotkb:NSP49(gene name synonym)|uniprotkb:YGL172W(locus name)|uniprotkb:G1648(orf name)|uniprotkb:Nuclear pore protein NUP49/NSP49(gene name synonym) psi-mi:nup49_yeast(display_long)|uniprotkb:NUP49(gene name)|psi-mi:NUP49(display_short)|uniprotkb:NSP49(gene name synonym)|uniprotkb:YGL172W(locus name)|uniprotkb:G1648(orf name)|uniprotkb:Nuclear pore protein NUP49/NSP49(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340056|imex:IM-14275-2375 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011343.1|sgd:S000003140|ensemblfungi:YGL172W(gene)|ensemblfungi:YGL172W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR024864|interpro:IPR025574|interpro:IPR039079|mint:Q02199|dip:DIP-709N refseq:NP_011343.1|sgd:S000003140|ensemblfungi:YGL172W(gene)|ensemblfungi:YGL172W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR024864|interpro:IPR025574|interpro:IPR039079|mint:Q02199|dip:DIP-709N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2x0Rt5ViHxBEKxPzOcfnyOdgmpg559292 rogid:2x0Rt5ViHxBEKxPzOcfnyOdgmpg559292 intact-crc:E007AA54332267FA|rigid:q5OI7yx1dHiPcg3AD/ihRGeM73M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06142 uniprotkb:Q02199 intact:EBI-9145|ensemblfungi:YLR347C|uniprotkb:D6VYY6 intact:EBI-12315|ensemblfungi:YGL172W|uniprotkb:D6VTY0 psi-mi:imb1_yeast(display_long)|uniprotkb:KAP95(gene name)|psi-mi:KAP95(display_short)|uniprotkb:YLR347C(locus name)|uniprotkb:L8300.15(orf name)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Karyopherin-95(gene name synonym)|uniprotkb:Importin-95(gene name synonym) psi-mi:nup49_yeast(display_long)|uniprotkb:NUP49(gene name)|psi-mi:NUP49(display_short)|uniprotkb:NSP49(gene name synonym)|uniprotkb:YGL172W(locus name)|uniprotkb:G1648(orf name)|uniprotkb:Nuclear pore protein NUP49/NSP49(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340067|imex:IM-14275-2376 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3EA5|rcsb pdb:3ND2|rcsb pdb:5OWU|reactome:R-SCE-2995383|reactome:R-SCE-6798695|ensemblfungi:YLR347C(gene)|ensemblfungi:YLR347C_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|rcsb pdb:2BKU|go:"GO:0006612"(protein targeting to membrane)|refseq:NP_013451.1|sgd:S000004339|dip:DIP-2357N|mint:Q06142 refseq:NP_011343.1|sgd:S000003140|ensemblfungi:YGL172W(gene)|ensemblfungi:YGL172W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR024864|interpro:IPR025574|interpro:IPR039079|mint:Q02199|dip:DIP-709N psi-mi:"MI:0469"(intact) crc64:ED530F5313E75B06 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ebWeXaUKiBFWgjdv9s2pz1GIqgI559292 rogid:2x0Rt5ViHxBEKxPzOcfnyOdgmpg559292 intact-crc:5D253E0F192D68E2|rigid:/5V5r+2LumyWYiBxAIgtTUCGoqY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02205 uniprotkb:P32610 intact:EBI-27062|uniprotkb:D6VX73|ensemblfungi:YKR007W intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W psi-mi:meh1_yeast(display_long)|uniprotkb:GSE complex subunit 2(gene name synonym)|uniprotkb:EGO complex subunit 1(gene name synonym)|uniprotkb:YKR007W(locus name)|uniprotkb:YK106(orf name)|uniprotkb:MEH1(gene name)|psi-mi:MEH1(display_short)|uniprotkb:EGO1(gene name synonym)|uniprotkb:GSE2(gene name synonym) psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340078|imex:IM-14275-2377 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001715|refseq:NP_012932.1|mint:Q02205|dip:DIP-1922N|ensemblfungi:YKR007W(gene)|ensemblfungi:YKR007W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0005829"(cytosol)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007040"(lysosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR028209|rcsb pdb:4XPM|rcsb pdb:6JWP refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610 psi-mi:"MI:0469"(intact) crc64:995DD1E68331D050 crc64:FDE93E1FAF0AEC5B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:73a6e5W5wQixGg2aGXDo4A6NR2s559292 rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292 intact-crc:24C62DB2A07C44C1|rigid:G0MB2KPa8q46GMzHu2nO+sRwcdQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38247 uniprotkb:Q02205 intact:EBI-21507|uniprotkb:D6VQ76|ensemblfungi:YBR077C intact:EBI-27062|uniprotkb:D6VX73|ensemblfungi:YKR007W psi-mi:slm4_yeast(display_long)|uniprotkb:YBR077C(locus name)|uniprotkb:YBR0723(orf name)|uniprotkb:GSE complex subunit 1(gene name synonym)|uniprotkb:EGO complex subunit 3(gene name synonym)|uniprotkb:SLM4(gene name)|psi-mi:SLM4(display_short)|uniprotkb:EGO3(gene name synonym)|uniprotkb:GSE1(gene name synonym) psi-mi:meh1_yeast(display_long)|uniprotkb:GSE complex subunit 2(gene name synonym)|uniprotkb:EGO complex subunit 1(gene name synonym)|uniprotkb:YKR007W(locus name)|uniprotkb:YK106(orf name)|uniprotkb:MEH1(gene name)|psi-mi:MEH1(display_short)|uniprotkb:EGO1(gene name synonym)|uniprotkb:GSE2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340089|imex:IM-14275-2378 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009633.3|sgd:S000000281|mint:P38247|dip:DIP-1763N|ensemblfungi:YBR077C(gene)|ensemblfungi:YBR077C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0071986"(Ragulator complex)|interpro:IPR020233|rcsb pdb:3LGO|rcsb pdb:4FTX|rcsb pdb:4FUW|rcsb pdb:4XPM|rcsb pdb:6JWP sgd:S000001715|refseq:NP_012932.1|mint:Q02205|dip:DIP-1922N|ensemblfungi:YKR007W(gene)|ensemblfungi:YKR007W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0005829"(cytosol)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007040"(lysosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR028209|rcsb pdb:4XPM|rcsb pdb:6JWP psi-mi:"MI:0469"(intact) crc64:D64ABDE1CDF265FD crc64:995DD1E68331D050 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BCEWjA3PQvwm3n08QwY0D//TpbA559292 rogid:73a6e5W5wQixGg2aGXDo4A6NR2s559292 intact-crc:3E940C67844ACB81|rigid:1agN6J4PcldSswPiG17ZcKgJtgQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02205 uniprotkb:P39968 intact:EBI-27062|uniprotkb:D6VX73|ensemblfungi:YKR007W intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W psi-mi:meh1_yeast(display_long)|uniprotkb:GSE complex subunit 2(gene name synonym)|uniprotkb:EGO complex subunit 1(gene name synonym)|uniprotkb:YKR007W(locus name)|uniprotkb:YK106(orf name)|uniprotkb:MEH1(gene name)|psi-mi:MEH1(display_short)|uniprotkb:EGO1(gene name synonym)|uniprotkb:GSE2(gene name synonym) psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340100|imex:IM-14275-2379 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001715|refseq:NP_012932.1|mint:Q02205|dip:DIP-1922N|ensemblfungi:YKR007W(gene)|ensemblfungi:YKR007W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0005829"(cytosol)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007040"(lysosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR028209|rcsb pdb:4XPM|rcsb pdb:6JWP sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N psi-mi:"MI:0469"(intact) crc64:995DD1E68331D050 crc64:B2E75774B47E5933 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:73a6e5W5wQixGg2aGXDo4A6NR2s559292 rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292 intact-crc:F6E2483C54B81B94|rigid:RdFJDayfyBqXmi3mZ7aZjV91d2c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02205 uniprotkb:P53191 intact:EBI-27062|uniprotkb:D6VX73|ensemblfungi:YKR007W intact:EBI-13400|uniprotkb:E9P8Z2|uniprotkb:D6VUB4|ensemblfungi:YGL023C psi-mi:meh1_yeast(display_long)|uniprotkb:GSE complex subunit 2(gene name synonym)|uniprotkb:EGO complex subunit 1(gene name synonym)|uniprotkb:YKR007W(locus name)|uniprotkb:YK106(orf name)|uniprotkb:MEH1(gene name)|psi-mi:MEH1(display_short)|uniprotkb:EGO1(gene name synonym)|uniprotkb:GSE2(gene name synonym) psi-mi:pib2_yeast(display_long)|uniprotkb:PIB2(gene name)|psi-mi:PIB2(display_short)|uniprotkb:YGL023C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340111|imex:IM-14275-2380 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001715|refseq:NP_012932.1|mint:Q02205|dip:DIP-1922N|ensemblfungi:YKR007W(gene)|ensemblfungi:YKR007W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0005829"(cytosol)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007040"(lysosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR028209|rcsb pdb:4XPM|rcsb pdb:6JWP refseq:NP_011492.3|sgd:S000002991|ensemblfungi:YGL023C(gene)|ensemblfungi:YGL023C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|mint:P53191|dip:DIP-6378N psi-mi:"MI:0469"(intact) crc64:995DD1E68331D050 crc64:512E9B873E6E0164 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:73a6e5W5wQixGg2aGXDo4A6NR2s559292 rogid:3T1+dWkNV7dfKQf0/9hJkjQbRW4559292 intact-crc:1A30E3B47EF1268B|rigid:NW9noXkcLxK96+F6rQNkhlwlT6s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02205 uniprotkb:P53290 intact:EBI-27062|uniprotkb:D6VX73|ensemblfungi:YKR007W intact:EBI-7962|uniprotkb:D6VUU7|ensemblfungi:YGR163W psi-mi:meh1_yeast(display_long)|uniprotkb:GSE complex subunit 2(gene name synonym)|uniprotkb:EGO complex subunit 1(gene name synonym)|uniprotkb:YKR007W(locus name)|uniprotkb:YK106(orf name)|uniprotkb:MEH1(gene name)|psi-mi:MEH1(display_short)|uniprotkb:EGO1(gene name synonym)|uniprotkb:GSE2(gene name synonym) psi-mi:gtr2_yeast(display_long)|uniprotkb:YGR163W(locus name)|uniprotkb:GTR2(gene name)|psi-mi:GTR2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340122|imex:IM-14275-2381 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001715|refseq:NP_012932.1|mint:Q02205|dip:DIP-1922N|ensemblfungi:YKR007W(gene)|ensemblfungi:YKR007W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0005829"(cytosol)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007040"(lysosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR028209|rcsb pdb:4XPM|rcsb pdb:6JWP sgd:S000003395|refseq:NP_011679.3|mint:P53290|dip:DIP-4521N|ensemblfungi:YGR163W(gene)|ensemblfungi:YGR163W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000785"(chromatin)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039400|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 psi-mi:"MI:0469"(intact) crc64:995DD1E68331D050 crc64:0A0D16C81F73184D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:73a6e5W5wQixGg2aGXDo4A6NR2s559292 rogid:+b9bPvzin/YUc5fOZZVCcFu/GEM559292 intact-crc:F80140B0C3857943|rigid:awgzTaC/fJ5bLLQpnTMJa4jMqc8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02205 uniprotkb:Q00582 intact:EBI-27062|uniprotkb:D6VX73|ensemblfungi:YKR007W intact:EBI-7954|uniprotkb:D6W0G3|ensemblfungi:YML121W psi-mi:meh1_yeast(display_long)|uniprotkb:GSE complex subunit 2(gene name synonym)|uniprotkb:EGO complex subunit 1(gene name synonym)|uniprotkb:YKR007W(locus name)|uniprotkb:YK106(orf name)|uniprotkb:MEH1(gene name)|psi-mi:MEH1(display_short)|uniprotkb:EGO1(gene name synonym)|uniprotkb:GSE2(gene name synonym) psi-mi:gtr1_yeast(display_long)|uniprotkb:YM7056.05(orf name)|uniprotkb:YML121W(locus name)|uniprotkb:GTR1(gene name)|psi-mi:GTR1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340133|imex:IM-14275-2382 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001715|refseq:NP_012932.1|mint:Q02205|dip:DIP-1922N|ensemblfungi:YKR007W(gene)|ensemblfungi:YKR007W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0005829"(cytosol)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007040"(lysosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR028209|rcsb pdb:4XPM|rcsb pdb:6JWP refseq:NP_013585.1|sgd:S000004590|mint:Q00582|dip:DIP-1358N|ensemblfungi:YML121W(gene)|ensemblfungi:YML121W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006348"|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039397|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 psi-mi:"MI:0469"(intact) crc64:995DD1E68331D050 crc64:B79CE7FE7AD2FDBE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:73a6e5W5wQixGg2aGXDo4A6NR2s559292 rogid:5LJU5zMF4NDDY9Bmndu0Q+JIm54559292 intact-crc:9C9AEEB6B7B50FE2|rigid:gMYfN2LbFKlgWBqYRyKr/v+zmzU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02205 uniprotkb:Q02205 intact:EBI-27062|uniprotkb:D6VX73|ensemblfungi:YKR007W intact:EBI-27062|uniprotkb:D6VX73|ensemblfungi:YKR007W psi-mi:meh1_yeast(display_long)|uniprotkb:GSE complex subunit 2(gene name synonym)|uniprotkb:EGO complex subunit 1(gene name synonym)|uniprotkb:YKR007W(locus name)|uniprotkb:YK106(orf name)|uniprotkb:MEH1(gene name)|psi-mi:MEH1(display_short)|uniprotkb:EGO1(gene name synonym)|uniprotkb:GSE2(gene name synonym) psi-mi:meh1_yeast(display_long)|uniprotkb:GSE complex subunit 2(gene name synonym)|uniprotkb:EGO complex subunit 1(gene name synonym)|uniprotkb:YKR007W(locus name)|uniprotkb:YK106(orf name)|uniprotkb:MEH1(gene name)|psi-mi:MEH1(display_short)|uniprotkb:EGO1(gene name synonym)|uniprotkb:GSE2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340144|imex:IM-14275-2383 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001715|refseq:NP_012932.1|mint:Q02205|dip:DIP-1922N|ensemblfungi:YKR007W(gene)|ensemblfungi:YKR007W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0005829"(cytosol)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007040"(lysosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR028209|rcsb pdb:4XPM|rcsb pdb:6JWP sgd:S000001715|refseq:NP_012932.1|mint:Q02205|dip:DIP-1922N|ensemblfungi:YKR007W(gene)|ensemblfungi:YKR007W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0005829"(cytosol)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007040"(lysosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR028209|rcsb pdb:4XPM|rcsb pdb:6JWP psi-mi:"MI:0469"(intact) crc64:995DD1E68331D050 crc64:995DD1E68331D050 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:73a6e5W5wQixGg2aGXDo4A6NR2s559292 rogid:73a6e5W5wQixGg2aGXDo4A6NR2s559292 intact-crc:2222ED53BE400576|rigid:C6BJZ2IpNgZe2AqDYyYDVR8j1Ig false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02206 uniprotkb:P40994 intact:EBI-16204|uniprotkb:Q6B1F7|ensemblfungi:YKR008W|uniprotkb:D6VX74 intact:EBI-2824|uniprotkb:D6W2F5|ensemblfungi:YOR094W psi-mi:rsc4_yeast(display_long)|uniprotkb:RSC4(gene name)|psi-mi:RSC4(display_short)|uniprotkb:RSC complex subunit RSC4(gene name synonym)|uniprotkb:YK107(orf name)|uniprotkb:YKR008W(locus name)|uniprotkb:Remodel the structure of chromatin complex subunit 4(gene name synonym) psi-mi:arf3_yeast(display_long)|uniprotkb:ARF3(gene name)|psi-mi:ARF3(display_short)|uniprotkb:YOR3172W(orf name)|uniprotkb:YOR094W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340155|imex:IM-14275-2384 author score:99.36 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YKR008W(gene)|ensemblfungi:YKR008W_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016586"(RSC-type complex)|go:"GO:0043044"|go:"GO:0070577"(lysine-acetylated histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR018359|interpro:IPR027180|interpro:IPR036427|interpro:IPR037382|rcsb pdb:2R0S|rcsb pdb:2R0V|rcsb pdb:2R0Y|rcsb pdb:2R10|rcsb pdb:6K15|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6TDA|rcsb pdb:6V8O|rcsb pdb:6V92|rcsb pdb:6KW3|sgd:S000001716|refseq:NP_012933.4|dip:DIP-6639N|mint:Q02206 refseq:NP_014737.1|sgd:S000005620|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P40994|interpro:IPR041838|ensemblfungi:YOR094W(gene)|ensemblfungi:YOR094W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010513"(positive regulation of phosphatidylinositol biosynthetic process)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0036267"(invasive filamentous growth)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.36|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wXu8mNFEsptlf+BTB1E3EzH5Od4559292 rogid:uC+fupPUZajD7m7pLEO/K0Kuudo559292 intact-crc:913B9B543957DB33|rigid:oA44zOsad6KwJs+qamjoIuu4Nvs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:Q02256 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-14322|uniprotkb:D6VVV7|ensemblfungi:YIR026C psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:pvh1_yeast(display_long)|uniprotkb:YIR026C(locus name)|uniprotkb:YVH1(gene name)|psi-mi:YVH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340166|imex:IM-14275-2385 author score:97.90 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) ensemblfungi:YIR026C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|ensemblfungi:YIR026C(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1990275"(preribosome binding)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|sgd:S000001465|interpro:IPR020422|interpro:IPR029021|rcsb pdb:6N8M|interpro:IPR016278(Tyrosine protein phosphatase, dual specificity, 12)|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6RZZ|rcsb pdb:6S05|refseq:NP_012292.3|mint:Q02256|dip:DIP-5192N psi-mi:"MI:0469"(intact) - crc64:9E75C7CC14353B43 figure legend:tables S3 and S4|author-confidence:97.90|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:9C9+S3aubsVjSLE5Kklpws+PA0A559292 intact-crc:BFDA98A58C1D7FB1|rigid:MOWeTus8lqQBAatFSGBwh6UHgSM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:Q02256 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-14322|uniprotkb:D6VVV7|ensemblfungi:YIR026C psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:pvh1_yeast(display_long)|uniprotkb:YIR026C(locus name)|uniprotkb:YVH1(gene name)|psi-mi:YVH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340177|imex:IM-14275-2386 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N ensemblfungi:YIR026C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|ensemblfungi:YIR026C(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1990275"(preribosome binding)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|sgd:S000001465|interpro:IPR020422|interpro:IPR029021|rcsb pdb:6N8M|interpro:IPR016278(Tyrosine protein phosphatase, dual specificity, 12)|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6RZZ|rcsb pdb:6S05|refseq:NP_012292.3|mint:Q02256|dip:DIP-5192N psi-mi:"MI:0469"(intact) - crc64:9E75C7CC14353B43 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:9C9+S3aubsVjSLE5Kklpws+PA0A559292 intact-crc:A4D5AFE927766C6B|rigid:Qx8Qc7AahDFqnyPyoYlAaOqb8Yk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:Q02256 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-14322|uniprotkb:D6VVV7|ensemblfungi:YIR026C psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:pvh1_yeast(display_long)|uniprotkb:YIR026C(locus name)|uniprotkb:YVH1(gene name)|psi-mi:YVH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340188|imex:IM-14275-2387 author score:97.90 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 ensemblfungi:YIR026C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|ensemblfungi:YIR026C(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1990275"(preribosome binding)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|sgd:S000001465|interpro:IPR020422|interpro:IPR029021|rcsb pdb:6N8M|interpro:IPR016278(Tyrosine protein phosphatase, dual specificity, 12)|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6RZZ|rcsb pdb:6S05|refseq:NP_012292.3|mint:Q02256|dip:DIP-5192N psi-mi:"MI:0469"(intact) - crc64:9E75C7CC14353B43 figure legend:tables S3 and S4|author-confidence:97.90|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:9C9+S3aubsVjSLE5Kklpws+PA0A559292 intact-crc:74F98CFE39132B2A|rigid:35ymZuo+3yGHnbxZpweU1PnkIMs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38344 uniprotkb:Q02256 intact:EBI-21136|uniprotkb:D6VQR3|ensemblfungi:YBR267W intact:EBI-14322|uniprotkb:D6VVV7|ensemblfungi:YIR026C psi-mi:rei1_yeast(display_long)|uniprotkb:REI1(gene name)|psi-mi:REI1(display_short)|uniprotkb:Required for isotropic bud growth protein 1(gene name synonym)|uniprotkb:pre-60S factor REI1(gene name synonym)|uniprotkb:YBR1736(orf name)|uniprotkb:YBR267W(locus name) psi-mi:pvh1_yeast(display_long)|uniprotkb:YIR026C(locus name)|uniprotkb:YVH1(gene name)|psi-mi:YVH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340199|imex:IM-14275-2388 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009825.4|sgd:S000000471|mint:P38344|dip:DIP-6347N|rcsb pdb:6RZZ|rcsb pdb:5APN|ensemblfungi:YBR267W(gene)|ensemblfungi:YBR267W_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR040025|interpro:IPR041661 ensemblfungi:YIR026C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|ensemblfungi:YIR026C(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1990275"(preribosome binding)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|sgd:S000001465|interpro:IPR020422|interpro:IPR029021|rcsb pdb:6N8M|interpro:IPR016278(Tyrosine protein phosphatase, dual specificity, 12)|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6RZZ|rcsb pdb:6S05|refseq:NP_012292.3|mint:Q02256|dip:DIP-5192N psi-mi:"MI:0469"(intact) crc64:D01AA8FFDF4A0BAC crc64:9E75C7CC14353B43 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YxMyWWxJUH2Pk41X+98x8jcnqhc559292 rogid:9C9+S3aubsVjSLE5Kklpws+PA0A559292 intact-crc:E7912D27936A19E4|rigid:mEWTTnmrR1ZKdcfEgevi52sHn2g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40582 uniprotkb:Q02256 intact:EBI-7941|uniprotkb:D6VVW9|ensemblfungi:YIR038C intact:EBI-14322|uniprotkb:D6VVV7|ensemblfungi:YIR026C psi-mi:gst1_yeast(display_long)|uniprotkb:YIR038C(locus name)|uniprotkb:GTT1(gene name)|psi-mi:GTT1(display_short)|uniprotkb:GST-I(gene name synonym) psi-mi:pvh1_yeast(display_long)|uniprotkb:YIR026C(locus name)|uniprotkb:YVH1(gene name)|psi-mi:YVH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340210|imex:IM-14275-2389 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012304.1|sgd:S000001477|mint:P40582|dip:DIP-2103N|ensemblfungi:YIR038C(gene)|ensemblfungi:YIR038C_mRNA(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010731"(protein glutathionylation)|go:"GO:0071944"(cell periphery)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079 ensemblfungi:YIR026C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|ensemblfungi:YIR026C(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1990275"(preribosome binding)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|sgd:S000001465|interpro:IPR020422|interpro:IPR029021|rcsb pdb:6N8M|interpro:IPR016278(Tyrosine protein phosphatase, dual specificity, 12)|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6RZZ|rcsb pdb:6S05|refseq:NP_012292.3|mint:Q02256|dip:DIP-5192N psi-mi:"MI:0469"(intact) crc64:3C07D40D29F60DFF crc64:9E75C7CC14353B43 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+bqzHpsoLw4j2qQBzHbkfldR5OU559292 rogid:9C9+S3aubsVjSLE5Kklpws+PA0A559292 intact-crc:10B8E8B80C7AC82A|rigid:b1O07zFS2JfbhReWhocyjg8/7sE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02256 uniprotkb:P50276 intact:EBI-14322|uniprotkb:D6VVV7|ensemblfungi:YIR026C intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:pvh1_yeast(display_long)|uniprotkb:YIR026C(locus name)|uniprotkb:YVH1(gene name)|psi-mi:YVH1(display_short) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340221|imex:IM-14275-2390 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YIR026C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|ensemblfungi:YIR026C(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1990275"(preribosome binding)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|sgd:S000001465|interpro:IPR020422|interpro:IPR029021|rcsb pdb:6N8M|interpro:IPR016278(Tyrosine protein phosphatase, dual specificity, 12)|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6RZZ|rcsb pdb:6S05|refseq:NP_012292.3|mint:Q02256|dip:DIP-5192N ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) crc64:9E75C7CC14353B43 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9C9+S3aubsVjSLE5Kklpws+PA0A559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:F4A63145A25A3B41|rigid:vShfpe7KpeOnMdxStwfoCF+VRoI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02256 uniprotkb:P53145 intact:EBI-14322|uniprotkb:D6VVV7|ensemblfungi:YIR026C intact:EBI-23885|uniprotkb:D6VU46|ensemblfungi:YGL099W psi-mi:pvh1_yeast(display_long)|uniprotkb:YIR026C(locus name)|uniprotkb:YVH1(gene name)|psi-mi:YVH1(display_short) psi-mi:lsg1_yeast(display_long)|uniprotkb:LSG1(gene name)|psi-mi:LSG1(display_short)|uniprotkb:YGL099W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340232|imex:IM-14275-2391 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YIR026C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|ensemblfungi:YIR026C(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1990275"(preribosome binding)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|sgd:S000001465|interpro:IPR020422|interpro:IPR029021|rcsb pdb:6N8M|interpro:IPR016278(Tyrosine protein phosphatase, dual specificity, 12)|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6RZZ|rcsb pdb:6S05|refseq:NP_012292.3|mint:Q02256|dip:DIP-5192N sgd:S000003067|refseq:NP_011416.3|dip:DIP-6659N|mint:P53145|ensemblfungi:YGL099W(gene)|ensemblfungi:YGL099W_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0043332"(mating projection tip)|interpro:IPR006073(GTP1/OBG)|interpro:IPR027417|interpro:IPR030378|interpro:IPR043358|rcsb pdb:5T62|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6QIK|rcsb pdb:6QTZ|rcsb pdb:6RI5|rcsb pdb:6RZZ|rcsb pdb:6S05 psi-mi:"MI:0469"(intact) crc64:9E75C7CC14353B43 crc64:15FD76541A2E8410 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9C9+S3aubsVjSLE5Kklpws+PA0A559292 rogid:9mANWO3rTsE/zCUr9GL6WxIexMU559292 intact-crc:7337A3EB681AD362|rigid:jCJhRIYwg6/LUYAZ/bW2vltwXRI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53388 uniprotkb:Q02256 intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W intact:EBI-14322|uniprotkb:D6VVV7|ensemblfungi:YIR026C psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:pvh1_yeast(display_long)|uniprotkb:YIR026C(locus name)|uniprotkb:YVH1(gene name)|psi-mi:YVH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340243|imex:IM-14275-2392 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) ensemblfungi:YIR026C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|ensemblfungi:YIR026C(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1990275"(preribosome binding)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|sgd:S000001465|interpro:IPR020422|interpro:IPR029021|rcsb pdb:6N8M|interpro:IPR016278(Tyrosine protein phosphatase, dual specificity, 12)|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6RZZ|rcsb pdb:6S05|refseq:NP_012292.3|mint:Q02256|dip:DIP-5192N psi-mi:"MI:0469"(intact) crc64:488A382656039D0B crc64:9E75C7CC14353B43 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 rogid:9C9+S3aubsVjSLE5Kklpws+PA0A559292 intact-crc:456561D8FC5EB868|rigid:N8Wg4Ka+O6bOlBJ6UZDb0ZlIKDY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02785 uniprotkb:Q02256 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C intact:EBI-14322|uniprotkb:D6VVV7|ensemblfungi:YIR026C psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:pvh1_yeast(display_long)|uniprotkb:YIR026C(locus name)|uniprotkb:YVH1(gene name)|psi-mi:YVH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340254|imex:IM-14275-2393 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) ensemblfungi:YIR026C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|ensemblfungi:YIR026C(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1990275"(preribosome binding)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|sgd:S000001465|interpro:IPR020422|interpro:IPR029021|rcsb pdb:6N8M|interpro:IPR016278(Tyrosine protein phosphatase, dual specificity, 12)|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6RZZ|rcsb pdb:6S05|refseq:NP_012292.3|mint:Q02256|dip:DIP-5192N psi-mi:"MI:0469"(intact) - crc64:9E75C7CC14353B43 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 rogid:9C9+S3aubsVjSLE5Kklpws+PA0A559292 intact-crc:9B2E045A7913229E|rigid:sTSZtqIHXy3jEShi1beI0BRPBEk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02256 uniprotkb:Q12462 intact:EBI-14322|uniprotkb:D6VVV7|ensemblfungi:YIR026C intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C psi-mi:pvh1_yeast(display_long)|uniprotkb:YIR026C(locus name)|uniprotkb:YVH1(gene name)|psi-mi:YVH1(display_short) psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340265|imex:IM-14275-2394 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YIR026C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|ensemblfungi:YIR026C(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1990275"(preribosome binding)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|sgd:S000001465|interpro:IPR020422|interpro:IPR029021|rcsb pdb:6N8M|interpro:IPR016278(Tyrosine protein phosphatase, dual specificity, 12)|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6RZZ|rcsb pdb:6S05|refseq:NP_012292.3|mint:Q02256|dip:DIP-5192N refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) psi-mi:"MI:0469"(intact) crc64:9E75C7CC14353B43 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9C9+S3aubsVjSLE5Kklpws+PA0A559292 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 intact-crc:E821345127FE473D|rigid:DGtXmVFAYzjaJdMI83N4bjkpRWk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02256 uniprotkb:Q12522 intact:EBI-14322|uniprotkb:D6VVV7|ensemblfungi:YIR026C intact:EBI-9046|ensemblfungi:YPR016C|uniprotkb:D6W426 psi-mi:pvh1_yeast(display_long)|uniprotkb:YIR026C(locus name)|uniprotkb:YVH1(gene name)|psi-mi:YVH1(display_short) psi-mi:if6_yeast(display_long)|uniprotkb:TIF6(gene name)|psi-mi:TIF6(display_short)|uniprotkb:CDC95(gene name synonym)|uniprotkb:YPR016C(locus name)|uniprotkb:LPZ15C(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340276|imex:IM-14275-2395 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YIR026C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|ensemblfungi:YIR026C(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1990275"(preribosome binding)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|sgd:S000001465|interpro:IPR020422|interpro:IPR029021|rcsb pdb:6N8M|interpro:IPR016278(Tyrosine protein phosphatase, dual specificity, 12)|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6RZZ|rcsb pdb:6S05|refseq:NP_012292.3|mint:Q02256|dip:DIP-5192N rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:6N8K|rcsb pdb:6N8L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R86|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:6EM1|rcsb pdb:6RZZ|rcsb pdb:6S05|rcsb pdb:6YLG|ensemblfungi:YPR016C(gene)|ensemblfungi:YPR016C_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR002769(Translation initiation factor IF6)|rcsb pdb:1G62|rcsb pdb:2X7N|rcsb pdb:3J2I|rcsb pdb:3JCT|rcsb pdb:4V7F|rcsb pdb:5FL8|rcsb pdb:5H4P|rcsb pdb:5JCS|rcsb pdb:5T62|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:7BTB|rcsb pdb:6YLH|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BT6|rcsb pdb:6ELZ|refseq:NP_015341.1|sgd:S000006220|mint:Q12522|dip:DIP-5395N psi-mi:"MI:0469"(intact) crc64:9E75C7CC14353B43 crc64:1BCE041C61DFD2A8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9C9+S3aubsVjSLE5Kklpws+PA0A559292 rogid:FI24/9LOZsCJEfbb7pjCQ+C8i/U559292 intact-crc:E20E8FC4B44FB3B0|rigid:1JrUUzw4bEjqckEsQJy8NnCUUYw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02555 uniprotkb:P07278 intact:EBI-15673|uniprotkb:D6W065|uniprotkb:Q04008|uniprotkb:Q05038|ensemblfungi:YMR239C intact:EBI-9475|ensemblfungi:YIL033C|uniprotkb:D6VVP9 psi-mi:rnt1_yeast(display_long)|uniprotkb:RNT1(gene name)|psi-mi:RNT1(display_short)|uniprotkb:YMR239C(locus name)|uniprotkb:YM9408.01C(orf name)|uniprotkb:YM9959.21(orf name)|uniprotkb:Ribonuclease III(gene name synonym) psi-mi:kapr_yeast(display_long)|uniprotkb:YIL033C(locus name)|uniprotkb:BCY1(gene name)|psi-mi:BCY1(display_short)|uniprotkb:REG1(gene name synonym)|uniprotkb:SRA1(gene name synonym)|uniprotkb:Bypass of cyclase mutations protein 1(gene name synonym)|uniprotkb:Protein kinase A regulatory subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340287|imex:IM-14275-2396 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013966.1|sgd:S000004852|ensemblfungi:YMR239C(gene)|ensemblfungi:YMR239C_mRNA(transcript)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030847"(termination of RNA polymerase II transcription, exosome-dependent)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0034963"(box C/D RNA processing)|go:"GO:0034964"(box H/ACA RNA processing)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|interpro:IPR000999(Ribonuclease III)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036389|interpro:IPR040540|interpro:IPR044449|rcsb pdb:1T4L|rcsb pdb:1T4N|rcsb pdb:1T4O|rcsb pdb:2LUP|rcsb pdb:2LUQ|rcsb pdb:4OOG|rcsb pdb:5T16|rcsb pdb:2LBS|dip:DIP-4298N|mint:Q02555 ensemblfungi:YIL033C(gene)|ensemblfungi:YIL033C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0030552"(cAMP binding)|go:"GO:0036278"(positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0061406"(positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|rcsb pdb:3OF1|rcsb pdb:6XQK|refseq:NP_012231.1|sgd:S000001295|mint:P07278|dip:DIP-551N psi-mi:"MI:0469"(intact) crc64:570294172E66A0DE crc64:6D7D97D8E4340AF3 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RskP9pfDLnItA8VCF7KUlaebZEQ559292 rogid:rSJ37UFoFiaHqc/2W5eYNx1qpbg559292 intact-crc:1669399B7C6DACC9|rigid:ohPxKaJS53w9JYx0Q/ca5T2TtKg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02574 uniprotkb:P35179 intact:EBI-10658|uniprotkb:P87260|uniprotkb:Q05887|ensemblfungi:YLR288C|uniprotkb:D6VYT4 intact:EBI-16406|ensemblfungi:YDR086C|uniprotkb:D6VS73 psi-mi:mec3_yeast(display_long)|uniprotkb:MEC3(gene name)|psi-mi:MEC3(display_short)|uniprotkb:PIP3(gene name synonym)|uniprotkb:YLR288C(locus name)|uniprotkb:L8003.15(orf name)|uniprotkb:PSO9(gene name synonym) psi-mi:sc61g_yeast(display_long)|uniprotkb:Sec61 complex subunit SSS1(gene name synonym)|uniprotkb:Ssh1 complex subunit SSS1(gene name synonym)|uniprotkb:D4475(orf name)|uniprotkb:YDR086C(locus name)|uniprotkb:SSS1(gene name)|psi-mi:SSS1(display_short)|uniprotkb:Sec61 complex subunit gamma(gene name synonym)|uniprotkb:Ssh1 complex subunit gamma(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340298|imex:IM-14275-2397 author score:97.90 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013391.1|sgd:S000004279|ensemblfungi:YLR288C(gene)|ensemblfungi:YLR288C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006348"|go:"GO:0030896"(checkpoint clamp complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0035861"(site of double-strand break)|go:"GO:0044778"(meiotic DNA integrity checkpoint signaling)|interpro:IPR007150(Hus1-like protein)|reactome:R-SCE-176187|mint:Q02574|dip:DIP-1432N ensemblfungi:YDR086C(gene)|ensemblfungi:YDR086C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|rcsb pdb:2WW9|rcsb pdb:2WWA|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|reactome:R-SCE-9609523|refseq:NP_010371.1|sgd:S000002493|dip:DIP-2432N|mint:P35179 psi-mi:"MI:0469"(intact) crc64:4385CEFA9130FEA3 - figure legend:tables S3 and S4|author-confidence:97.90|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:LuYCya9O8z1Uw0xyfJnz3aowolg559292 rogid:QIi5kN/8mDxTSvxRiJVi2JsPdws559292 intact-crc:A26530BC03864C9E|rigid:eogryck1K6SVDzsyRTRh0ed55cA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02574 uniprotkb:Q07844 intact:EBI-10658|uniprotkb:P87260|uniprotkb:Q05887|ensemblfungi:YLR288C|uniprotkb:D6VYT4 intact:EBI-27142|uniprotkb:D6VXX1|ensemblfungi:YLL034C psi-mi:mec3_yeast(display_long)|uniprotkb:MEC3(gene name)|psi-mi:MEC3(display_short)|uniprotkb:PIP3(gene name synonym)|uniprotkb:YLR288C(locus name)|uniprotkb:L8003.15(orf name)|uniprotkb:PSO9(gene name synonym) psi-mi:rix7_yeast(display_long)|uniprotkb:RIX7(gene name)|psi-mi:RIX7(display_short)|uniprotkb:YLL034C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340309|imex:IM-14275-2398 author score:97.90 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013391.1|sgd:S000004279|ensemblfungi:YLR288C(gene)|ensemblfungi:YLR288C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006348"|go:"GO:0030896"(checkpoint clamp complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0035861"(site of double-strand break)|go:"GO:0044778"(meiotic DNA integrity checkpoint signaling)|interpro:IPR007150(Hus1-like protein)|reactome:R-SCE-176187|mint:Q02574|dip:DIP-1432N refseq:NP_013066.1|sgd:S000003957|mint:Q07844|dip:DIP-6385N|ensemblfungi:YLL034C(gene)|ensemblfungi:YLL034C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990275"(preribosome binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569 psi-mi:"MI:0469"(intact) crc64:4385CEFA9130FEA3 crc64:133528B9D0987103 figure legend:tables S3 and S4|author-confidence:97.90|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:LuYCya9O8z1Uw0xyfJnz3aowolg559292 rogid:CEDaCFQQsHNDc1vhyXrgiMUNzO4559292 intact-crc:98247FF6BB0D9644|rigid:h4Dp96Tnm+8isnc1jS0owDx1WW8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02629 uniprotkb:P40064 intact:EBI-11698|ensemblfungi:YKL068W|uniprotkb:D6VXL9 intact:EBI-11740|ensemblfungi:YER105C|uniprotkb:D3DM12 psi-mi:nu100_yeast(display_long)|uniprotkb:NUP100(gene name)|psi-mi:NUP100(display_short)|uniprotkb:NSP100(gene name synonym)|uniprotkb:YKL068W(locus name)|uniprotkb:YKL336(orf name)|uniprotkb:Nuclear pore protein NUP100/NSP100(gene name synonym) psi-mi:nu157_yeast(display_long)|uniprotkb:YER105C(locus name)|uniprotkb:NUP157(gene name)|psi-mi:NUP157(display_short)|uniprotkb:Nuclear pore protein NUP157(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340320|imex:IM-14275-2399 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YKL068W(gene)|ensemblfungi:YKL068W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005643"(nuclear pore)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|refseq:NP_012855.1|sgd:S000001551|mint:Q02629|dip:DIP-2351N ensemblfungi:YER105C(gene)|ensemblfungi:YER105C_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|rcsb pdb:4MHC|refseq:NP_011031.1|sgd:S000000907|mint:P40064|dip:DIP-846N psi-mi:"MI:0469"(intact) crc64:D3985F9901BBAA51 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cdG/6Bz1Q30Of8KHqHp7FGTaOR8559292 rogid:vKznZjOxKUw5Bo+4LemfCkzdBxg559292 intact-crc:B39834B5B5133BE9|rigid:im7eOOnd9U21gF/4/IsbLLI3il4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02629 uniprotkb:P40368 intact:EBI-11698|ensemblfungi:YKL068W|uniprotkb:D6VXL9 intact:EBI-12331|ensemblfungi:YJL061W|uniprotkb:D6VWC1 psi-mi:nu100_yeast(display_long)|uniprotkb:NUP100(gene name)|psi-mi:NUP100(display_short)|uniprotkb:NSP100(gene name synonym)|uniprotkb:YKL068W(locus name)|uniprotkb:YKL336(orf name)|uniprotkb:Nuclear pore protein NUP100/NSP100(gene name synonym) psi-mi:nup82_yeast(display_long)|uniprotkb:NUP82(gene name)|psi-mi:NUP82(display_short)|uniprotkb:YJL061W(locus name)|uniprotkb:J1135(orf name)|uniprotkb:HRB187(orf name)|uniprotkb:Nuclear pore protein NUP82(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340331|imex:IM-14275-2400 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YKL068W(gene)|ensemblfungi:YKL068W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005643"(nuclear pore)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|refseq:NP_012855.1|sgd:S000001551|mint:Q02629|dip:DIP-2351N refseq:NP_012474.1|sgd:S000003597|ensemblfungi:YJL061W(gene)|ensemblfungi:YJL061W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|interpro:IPR037700|rcsb pdb:3PBP|rcsb pdb:3TKN|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|mint:P40368|dip:DIP-913N psi-mi:"MI:0469"(intact) crc64:D3985F9901BBAA51 crc64:C379B5E111E26B50 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cdG/6Bz1Q30Of8KHqHp7FGTaOR8559292 rogid:g1+jqOMmde8phrNI9H7nFlXwjH0559292 intact-crc:5CA99782AB345F7B|rigid:ZXzGbZdfnUvJfZ7CACuZUSG8UzI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02630 uniprotkb:Q02629 intact:EBI-11703|ensemblfungi:YMR047C|uniprotkb:D6VZM2 intact:EBI-11698|ensemblfungi:YKL068W|uniprotkb:D6VXL9 psi-mi:nu116_yeast(display_long)|uniprotkb:NUP116(gene name)|psi-mi:NUP116(display_short)|uniprotkb:NSP116(gene name synonym)|uniprotkb:YMR047C(locus name)|uniprotkb:YM9532.12C(orf name)|uniprotkb:Nuclear pore protein NUP116/NSP116(gene name synonym) psi-mi:nu100_yeast(display_long)|uniprotkb:NUP100(gene name)|psi-mi:NUP100(display_short)|uniprotkb:NSP100(gene name synonym)|uniprotkb:YKL068W(locus name)|uniprotkb:YKL336(orf name)|uniprotkb:Nuclear pore protein NUP100/NSP100(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340342|imex:IM-14275-2401 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR047C(gene)|ensemblfungi:YMR047C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0051117"(ATPase binding)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|rcsb pdb:1O6P|rcsb pdb:2AIV|rcsb pdb:3PBP|go:"GO:0017056"(structural constituent of nuclear pore)|refseq:NP_013762.1|sgd:S000004650|mint:Q02630|dip:DIP-2389N ensemblfungi:YKL068W(gene)|ensemblfungi:YKL068W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005643"(nuclear pore)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|refseq:NP_012855.1|sgd:S000001551|mint:Q02629|dip:DIP-2351N psi-mi:"MI:0469"(intact) crc64:FBAB0B9AEA958213 crc64:D3985F9901BBAA51 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZuiHiCdDSP9OqFdd1+fJ07WNe7Y559292 rogid:cdG/6Bz1Q30Of8KHqHp7FGTaOR8559292 intact-crc:44A5FB235DD10C8C|rigid:0WQGPMAMpyUzqy39cDRDlq2KjS8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02629 uniprotkb:Q06142 intact:EBI-11698|ensemblfungi:YKL068W|uniprotkb:D6VXL9 intact:EBI-9145|ensemblfungi:YLR347C|uniprotkb:D6VYY6 psi-mi:nu100_yeast(display_long)|uniprotkb:NUP100(gene name)|psi-mi:NUP100(display_short)|uniprotkb:NSP100(gene name synonym)|uniprotkb:YKL068W(locus name)|uniprotkb:YKL336(orf name)|uniprotkb:Nuclear pore protein NUP100/NSP100(gene name synonym) psi-mi:imb1_yeast(display_long)|uniprotkb:KAP95(gene name)|psi-mi:KAP95(display_short)|uniprotkb:YLR347C(locus name)|uniprotkb:L8300.15(orf name)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Karyopherin-95(gene name synonym)|uniprotkb:Importin-95(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340353|imex:IM-14275-2402 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YKL068W(gene)|ensemblfungi:YKL068W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005643"(nuclear pore)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|refseq:NP_012855.1|sgd:S000001551|mint:Q02629|dip:DIP-2351N rcsb pdb:3EA5|rcsb pdb:3ND2|rcsb pdb:5OWU|reactome:R-SCE-2995383|reactome:R-SCE-6798695|ensemblfungi:YLR347C(gene)|ensemblfungi:YLR347C_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|rcsb pdb:2BKU|go:"GO:0006612"(protein targeting to membrane)|refseq:NP_013451.1|sgd:S000004339|dip:DIP-2357N|mint:Q06142 psi-mi:"MI:0469"(intact) crc64:D3985F9901BBAA51 crc64:ED530F5313E75B06 figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cdG/6Bz1Q30Of8KHqHp7FGTaOR8559292 rogid:ebWeXaUKiBFWgjdv9s2pz1GIqgI559292 intact-crc:4F0E2A6F311E1CE4|rigid:IdzBoP+vCxDiWX/lY+Tihqcr/Nk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02774 uniprotkb:P06775 intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 intact:EBI-8308|uniprotkb:D6VUX3|ensemblfungi:YGR191W psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:hip1_yeast(display_long)|uniprotkb:G7572(orf name)|uniprotkb:YGR191W(locus name)|uniprotkb:HIP1(gene name)|psi-mi:HIP1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340364|imex:IM-14275-2403 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 refseq:NP_011707.1|sgd:S000003423|mint:P06775|dip:DIP-5549N|ensemblfungi:YGR191W(gene)|ensemblfungi:YGR191W_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005291"(high-affinity L-histidine transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006828"(manganese ion transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) psi-mi:"MI:0469"(intact) - crc64:77DD34F1DA95E75F figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 rogid:FUVjfzZjOKVuqqOQfcVlNmw4nO4559292 intact-crc:4061F58BA0DB26B1|rigid:teRL1mu0vgeaYTwU80/XevIPHI0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:Q02774 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340375|imex:IM-14275-2404 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 intact-crc:BF730BF667290D50|rigid:CFLmcv+Va2LHm9vj12eZEZA1N28 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:Q02774 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340386|imex:IM-14275-2405 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 psi-mi:"MI:0469"(intact) crc64:8B7F009521F72C15 - figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 intact-crc:27C0DD332BFDA501|rigid:A+PVkbSDQBMJ5GMkpXmho8yv29Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35206 uniprotkb:Q02774 intact:EBI-2051140|uniprotkb:D6VQ36|ensemblfungi:YBR036C intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 psi-mi:csg2_yeast(display_long)|uniprotkb:CLS2(gene name synonym)|uniprotkb:YBR0404(orf name)|uniprotkb:YBR036C(locus name)|uniprotkb:CSG2(gene name)|psi-mi:CSG2(display_short) psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340397|imex:IM-14275-2406 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000240|refseq:NP_009592.1|dip:DIP-8095N|mint:P35206|ensemblfungi:YBR036C(gene)|ensemblfungi:YBR036C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006688"(glycosphingolipid biosynthetic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030234"(enzyme regulator activity)|interpro:IPR018247|interpro:IPR031581 refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:EHDjwiK1XOXY3MEZ03X2l1fu/MQ559292 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 intact-crc:0CD120C4DB75A7EB|rigid:OLYXeY4+v3Jte6Yp3fD7eIbWh7Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02774 uniprotkb:P38084 intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 intact:EBI-3414|uniprotkb:D6VQ67|ensemblfungi:YBR068C psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:bap2_yeast(display_long)|uniprotkb:Branched-chain amino-acid permease 2(gene name synonym)|uniprotkb:BAP2(gene name)|psi-mi:BAP2(display_short)|uniprotkb:YBR068C(locus name)|uniprotkb:YBR0629(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340408|imex:IM-14275-2407 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 sgd:S000000272|refseq:NP_009624.4|dip:DIP-4910N|mint:P38084|ensemblfungi:YBR068C(gene)|ensemblfungi:YBR068C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015192"(L-phenylalanine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098713"(leucine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) psi-mi:"MI:0469"(intact) - crc64:B87FD6A7464E07F5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 rogid:7Fw7+M5mBikZBztHE2tSDpvBi/M559292 intact-crc:4DF5CB20846412FD|rigid:LyYFUdA2k0VxpUCwq2yPxKHUuyI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:Q02774 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340419|imex:IM-14275-2408 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 intact-crc:A8650920BA09B19D|rigid:d9wlPRNK9BLh6TNvUWqwYtj4Lg4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02774 uniprotkb:P40540 intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340430|imex:IM-14275-2409 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) - crc64:6DBEEEE7722203B0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 intact-crc:5BEDADB6618A343D|rigid:op23o92SoTFhQ51WEissFTUekYw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02774 uniprotkb:P53388 intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340441|imex:IM-14275-2410 author score:87.56 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) psi-mi:"MI:0469"(intact) - crc64:488A382656039D0B figure legend:tables S3 and S4|author-confidence:87.56|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 intact-crc:1AB983AFD462EE58|rigid:/cwrODEMdKTI9X9+pi2rJyzYbdQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:Q02774 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340452|imex:IM-14275-2411 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 intact-crc:BAA503C22DE72098|rigid:8avC5Qth/8dOVkS5225EfJAphj8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02774 uniprotkb:Q02774 intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340463|imex:IM-14275-2412 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 intact-crc:41640D1DECAE9888|rigid:XCSy0NSl/1hVfclzM+Q2Tbqx8jw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02774 uniprotkb:Q03697 intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 intact:EBI-27776|uniprotkb:D6VZD7|ensemblfungi:YML038C psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:ymd8_yeast(display_long)|uniprotkb:YML038C(locus name)|uniprotkb:YMD8(gene name)|psi-mi:YMD8(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340474|imex:IM-14275-2413 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 refseq:NP_013674.1|sgd:S000004502|dip:DIP-1312N|mint:Q03697|ensemblfungi:YML038C(gene)|ensemblfungi:YML038C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005338"(nucleotide-sugar transmembrane transporter activity)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015297"(antiporter activity)|go:"GO:0015780"(nucleotide-sugar transmembrane transport)|go:"GO:0015786"(UDP-glucose transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030663"(COPI-coated vesicle membrane)|interpro:IPR004853(Protein of unknown function DUF250) psi-mi:"MI:0469"(intact) - crc64:37A03543D3AB695E figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 rogid:i2Fqb84s31vBiayw4lJW8o3S3WU559292 intact-crc:CC7F9782DD4CE293|rigid:VVX9/msPmpUTKiSg/hh8ErYt3Ec false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02774 uniprotkb:Q06144 intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340485|imex:IM-14275-2414 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:2F474503CAB7C195 figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 intact-crc:CF9A57485988C0C4|rigid:+g8cx9flNJynkKWQOGi/YjFtIT0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02775 uniprotkb:Q3E7A4 intact:EBI-17379|uniprotkb:P89902|uniprotkb:Q6Q5U3|uniprotkb:D6VS75|ensemblfungi:YDR088C intact:EBI-2088942|uniprotkb:D6VPU0|ensemblfungi:YBL059C-A psi-mi:slu7_yeast(display_long)|uniprotkb:SLU7(gene name)|psi-mi:SLU7(display_short)|uniprotkb:YDR088C(locus name)|uniprotkb:D4483(orf name)|uniprotkb:SLT17(gene name synonym)|uniprotkb:Synthetic lethal with U5 snRNA protein 7(gene name synonym)|uniprotkb:Synthetic lethal with U2 snRNA protein 17(gene name synonym) psi-mi:coxm2_yeast(display_long)|uniprotkb:CMC2(gene name)|psi-mi:CMC2(display_short)|uniprotkb:Mitochondrial metallochaperone-like protein CMC2(gene name synonym)|uniprotkb:YBL059C-A(locus name)|uniprotkb:Cx9C motif-containing protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340496|imex:IM-14275-2415 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010373.3|sgd:S000002495|ensemblfungi:YDR088C(gene)|ensemblfungi:YDR088C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000386"(second spliceosomal transesterification activity)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0071021"(U2-type post-spliceosomal complex)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR021715|interpro:IPR036875|interpro:IPR039974|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:5YLZ|mint:Q02775|dip:DIP-220N refseq:NP_031358.1|sgd:S000007488|interpro:IPR013892(Protein of unknown function UPF0287)|mint:Q3E7A4|ensemblfungi:YBL059C-A(gene)|ensemblfungi:YBL059C-A_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) crc64:6405458FC367A7D3 - figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:an3IJpPrRlLX0cALtTMg4C2JxUI559292 rogid:vFuTXY9PR1C1e6lQLldbF4TxINo559292 intact-crc:0D914F4073A86FCE|rigid:T19te7F5QQu96xSms4rjKGZ/9xg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47976 uniprotkb:Q02784 intact:EBI-5222|uniprotkb:D6VSD3|ensemblfungi:YDR151C intact:EBI-29427|uniprotkb:D6W3V5|ensemblfungi:YPL059W psi-mi:cth1_yeast(display_long)|uniprotkb:CTH1(gene name)|psi-mi:CTH1(display_short)|uniprotkb:YDR151C(locus name)|uniprotkb:YD8358.07C(orf name)|uniprotkb:Cysteine-three-histidine protein 1(gene name synonym) psi-mi:glrx5_yeast(display_long)|uniprotkb:LPE13W(orf name)|uniprotkb:YPL059W(locus name)|uniprotkb:GRX5(gene name)|psi-mi:GRX5(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340507|imex:IM-14275-2416 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010435.1|sgd:S000002558|dip:DIP-1784N|mint:P47976|ensemblfungi:YDR151C(gene)|ensemblfungi:YDR151C_mRNA(transcript)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|reactome:R-SCE-450385|reactome:R-SCE-450513 refseq:NP_015266.1|sgd:S000005980|dip:DIP-1352N|mint:Q02784|ensemblfungi:YPL059W(gene)|ensemblfungi:YPL059W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0097573"(glutathione oxidoreductase activity)|go:"GO:0106034"(protein maturation by [2Fe-2S] cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR033658|interpro:IPR036249|rcsb pdb:3GX8|reactome:R-SCE-1362409 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vbm5Yj+uA0Mhzj+DmgjYI9Kn/uY559292 rogid:BewcU5fU1vugLOIRw1Jj00uk6sA559292 intact-crc:5D119D9228998168|rigid:GVQZsC7eYDp8nMxtT0jbzHnJEhE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02793 uniprotkb:P16965 intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C intact:EBI-2045666|uniprotkb:D6VUE5|uniprotkb:P89099|ensemblfungi:YGR008C psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym) psi-mi:stf2_yeast(display_long)|uniprotkb:G3858(orf name)|uniprotkb:YGR008C(locus name)|uniprotkb:STF2(gene name)|psi-mi:STF2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340518|imex:IM-14275-2417 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793 refseq:NP_011522.1|sgd:S000003240|mint:P16965|ensemblfungi:YGR008C(gene)|ensemblfungi:YGR008C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0071465"(cellular response to desiccation) psi-mi:"MI:0469"(intact) crc64:C5E7B9D2268F9727 - figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292 rogid:Jg0WHw2YG9JnO2ke+FnQjnchklE559292 intact-crc:D2B15C35D8D63B6D|rigid:uXglgjWQ+YxGbH8RfsAafxNhZhI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20435 uniprotkb:Q02793 intact:EBI-15786|uniprotkb:D6W4I7|ensemblfungi:YPR187W intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C psi-mi:rpab2_yeast(display_long)|uniprotkb:RPO26(gene name)|psi-mi:RPO26(display_short)|uniprotkb:RPB6(gene name synonym)|uniprotkb:YPR187W(locus name)|uniprotkb:P9677.8(orf name)|uniprotkb:DNA-directed RNA polymerases I, II, and III 23 kDa polypeptide(gene name synonym)|uniprotkb:ABC23(gene name synonym) psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340529|imex:IM-14275-2418 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015513.1|sgd:S000006391|dip:DIP-2194N|mint:P20435|ensemblfungi:YPR187W(gene)|ensemblfungi:YPR187W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR006110(RNA polymerase Rpb6)|interpro:IPR006111(DNA-directed RNA polymerase, 14 to 18 kDa subunit)|interpro:IPR012293(RNA polymerase subunit, RPB6/omega)|interpro:IPR020708|interpro:IPR028363|interpro:IPR036161|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4YM7|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5G5L|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-77075|reactome:R-SCE-9018519 refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793 psi-mi:"MI:0469"(intact) crc64:AA3DEF529F94A5E4 crc64:C5E7B9D2268F9727 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3kKsSGEw5OOi+Yp6budfnxfr8SQ559292 rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292 intact-crc:3EBAA5526C1D1C45|rigid:DebLVgqW4WXiTFKbyEii9nJteh4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38009 uniprotkb:Q02793 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340540|imex:IM-14275-2419 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793 psi-mi:"MI:0469"(intact) crc64:8ABA71761B512242 crc64:C5E7B9D2268F9727 figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292 intact-crc:98E9D0921F52E5FC|rigid:i4+tQutem0wpm4Dnu77GU/MZM58 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02793 uniprotkb:Q02793 intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym) psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340551|imex:IM-14275-2420 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793 refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793 psi-mi:"MI:0469"(intact) crc64:C5E7B9D2268F9727 crc64:C5E7B9D2268F9727 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292 rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292 intact-crc:4D396043FC98884C|rigid:spPxmEhkfW2hLnkulO5fa/bj64M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08732 uniprotkb:Q02793 intact:EBI-37488|uniprotkb:Q07224|uniprotkb:D6W2W7|ensemblfungi:YOR267C intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C psi-mi:hrk1_yeast(display_long)|uniprotkb:YOR267C(locus name)|uniprotkb:HRK1(gene name)|psi-mi:HRK1(display_short)|uniprotkb:Hygromycin resistance kinase 1(gene name synonym) psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340562|imex:IM-14275-2421 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014910.1|sgd:S000005793|dip:DIP-6454N|mint:Q08732|ensemblfungi:YOR267C(gene)|ensemblfungi:YOR267C_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006873"(cellular ion homeostasis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site) refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793 psi-mi:"MI:0469"(intact) crc64:20522967DF1F6BE2 crc64:C5E7B9D2268F9727 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AHAXPU+eEbpmwWLkVk+PMd7oJEQ559292 rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292 intact-crc:B846FBB81E47E132|rigid:OvOPzsWPhVtlUO/7fEY9JEtQNm0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:Q02795 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340573|imex:IM-14275-2422 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N psi-mi:"MI:0469"(intact) - crc64:53D15B8857A534E5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 intact-crc:5DF65EB3A72EC833|rigid:MnJCk/CDkxmCekNP+Y4+OLuUmNo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:Q02795 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340584|imex:IM-14275-2423 author score:99.36 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 crc64:53D15B8857A534E5 figure legend:tables S3 and S4|author-confidence:99.36|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 intact-crc:B728550BC649664E|rigid:6js9G+TPnbkuLNN5Sh0Nka1lSnQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17260 uniprotkb:Q02795 intact:EBI-2068892|uniprotkb:D6W0M4|ensemblfungi:YNL322C intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W psi-mi:kre1_yeast(display_long)|uniprotkb:KRE1(gene name)|psi-mi:KRE1(display_short)|uniprotkb:N0336(orf name)|uniprotkb:YNL322C(locus name)|uniprotkb:Killer toxin-resistance protein 1(gene name synonym) psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340595|imex:IM-14275-2424 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005266|refseq:NP_014077.1|interpro:IPR031452|mint:P17260|ensemblfungi:YNL322C(gene)|ensemblfungi:YNL322C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005199"(structural constituent of cell wall)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031505"(fungal-type cell wall organization) ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N psi-mi:"MI:0469"(intact) - crc64:53D15B8857A534E5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BPFRfEQD1gAwbE9Nyfr/Xn33SDA559292 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 intact-crc:EF9456864DE82F26|rigid:5EFmOPUerD/nDiCapedjD8Fuddw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02795 uniprotkb:P17898 intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W intact:EBI-2050738|uniprotkb:D6W152|ensemblfungi:YNL130C psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:cpt1_yeast(display_long)|uniprotkb:Diacylglycerol cholinephosphotransferase 1(gene name synonym)|uniprotkb:Sn-1,2-diacylglycerol cholinephosphotransferase(gene name synonym)|uniprotkb:N1218(orf name)|uniprotkb:N1867(orf name)|uniprotkb:YNL130C(locus name)|uniprotkb:CPT1(gene name)|psi-mi:CPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase CPT1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340606|imex:IM-14275-2425 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N sgd:S000005074|refseq:NP_014269.4|dip:DIP-7848N|mint:P17898|ensemblfungi:YNL130C(gene)|ensemblfungi:YNL130C_mRNA(transcript)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006657"(CDP-choline pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213 psi-mi:"MI:0469"(intact) crc64:53D15B8857A534E5 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 rogid:PsU8UELFPsbtbzOS6oBnXJAuk/A559292 intact-crc:DA1E9CA39CD1DC02|rigid:MT+GP7txqX7pIr5wNIlFLzaj+n8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02795 uniprotkb:P19807 intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340617|imex:IM-14275-2426 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) crc64:53D15B8857A534E5 - figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:0284560764275CE2|rigid:DBsWa2XG7qaIOY86Teew50mBRFU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25334 uniprotkb:Q02795 intact:EBI-5468|ensemblfungi:YCR069W|uniprotkb:P25658|uniprotkb:D6VR72 intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W psi-mi:cypr_yeast(display_long)|uniprotkb:CPR4(gene name)|psi-mi:CPR4(display_short)|uniprotkb:CYP4(gene name synonym)|uniprotkb:SCC3(gene name synonym)|uniprotkb:YCR069W(locus name)|uniprotkb:YCR69W/YCR70W(orf name)|uniprotkb:Rotamase(gene name synonym) psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340628|imex:IM-14275-2427 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016021"(integral component of membrane)|ensemblfungi:YCR069W(gene)|ensemblfungi:YCR069W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|refseq:NP_009995.1|sgd:S000000665|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR029000|mint:P25334 ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N psi-mi:"MI:0469"(intact) - crc64:53D15B8857A534E5 figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tEV99GVg3yqyhYSsqnhEIFSIoUw559292 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 intact-crc:6CA738B70D4265D9|rigid:iI3gmTS+dQiAHHqjxMGjO0O67iE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02795 uniprotkb:P25361 intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W intact:EBI-21909|uniprotkb:D6VR52|ensemblfungi:YCR043C psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:yct3_yeast(display_long)|uniprotkb:YCR43C(orf name)|uniprotkb:YCR725(orf name)|uniprotkb:YCR043C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340639|imex:IM-14275-2428 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N sgd:S000000639|refseq:NP_009972.1|mint:P25361|ensemblfungi:YCR043C(gene)|ensemblfungi:YCR043C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0043332"(mating projection tip) psi-mi:"MI:0469"(intact) crc64:53D15B8857A534E5 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 rogid:bEMtsAa5vCsWqGOiXwBK40Pa0xQ559292 intact-crc:0B40EA715395036A|rigid:k3vGvZjXseh1ELML5eCMau1UGpA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02795 uniprotkb:P26570 intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340650|imex:IM-14275-2429 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N psi-mi:"MI:0469"(intact) crc64:53D15B8857A534E5 crc64:8B7F009521F72C15 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 intact-crc:C5419DD6EA4A6062|rigid:aX0dIzoJfmES1jaLjycRIB3bqsQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32915 uniprotkb:Q02795 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340661|imex:IM-14275-2430 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N psi-mi:"MI:0469"(intact) - crc64:53D15B8857A534E5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 intact-crc:878752ABD86D80A2|rigid:7//zkoWbsnwxNAm+TXvpNJdI+sA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02795 uniprotkb:P35196 intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W intact:EBI-14943|uniprotkb:D6VQ03|ensemblfungi:YBR002C psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:rer2_yeast(display_long)|uniprotkb:"Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific)"(gene name synonym)|uniprotkb:YBR0107(orf name)|uniprotkb:RER2(gene name)|psi-mi:RER2(display_short)|uniprotkb:YBR002C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340672|imex:IM-14275-2431 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N interpro:IPR036424|refseq:NP_009556.1|sgd:S000000206|interpro:IPR001441(Di-trans-poly-cis-decaprenylcistransferase)|interpro:IPR018520|ensemblfungi:YBR002C(gene)|ensemblfungi:YBR002C_mRNA(transcript)|go:"GO:0002094"(polyprenyltransferase activity)|go:"GO:0004659"(prenyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016094"(polyprenol biosynthetic process)|go:"GO:0019408"(dolichol biosynthetic process)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0045547"(dehydrodolichyl diphosphate synthase activity)|go:"GO:1904423"(dehydrodolichyl diphosphate synthase complex)|reactome:R-SCE-446199|mint:P35196 psi-mi:"MI:0469"(intact) crc64:53D15B8857A534E5 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 rogid:gVl9E/6GKqKsUp/5VLdT5XGbjUM559292 intact-crc:790CD6813A291058|rigid:kG+l+YKPJDFeileQlcrikzFbHUQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36024 uniprotkb:Q02795 intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym) psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340683|imex:IM-14275-2432 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024 ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N psi-mi:"MI:0469"(intact) - crc64:53D15B8857A534E5 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 intact-crc:C946054B68F2D608|rigid:xNgS4nDW/I67l5+NnkI5ge31o6w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36076 uniprotkb:Q02795 intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short) psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340694|imex:IM-14275-2433 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783 ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N psi-mi:"MI:0469"(intact) - crc64:53D15B8857A534E5 figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Li7vZOassm4PC5fW111/j5ivgEc559292 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 intact-crc:A9AC54F204497975|rigid:U1PjPl7n8IkSvFLPb0ANIfbzTAI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02795 uniprotkb:P36091 intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W intact:EBI-2052781|uniprotkb:D6VXP1|uniprotkb:Q66R60|ensemblfungi:YKL046C psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:dcw1_yeast(display_long)|uniprotkb:Endo-alpha-1->6-D-mannanase DCW1(gene name synonym)|uniprotkb:Defective cell wall 1(gene name synonym)|uniprotkb:YKL259(orf name)|uniprotkb:YKL046C(locus name)|uniprotkb:DCW1(gene name)|psi-mi:DCW1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340705|imex:IM-14275-2434 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N refseq:NP_012878.1|sgd:S000001529|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR005198(Glycoside hydrolase, family 76)|interpro:IPR014480(Mannan endo-1,6-alpha-mannosidase)|mint:P36091|ensemblfungi:YKL046C(gene)|ensemblfungi:YKL046C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005933"(cellular bud)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0008496"(mannan endo-1,6-alpha-mannosidase activity)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0071555"(cell wall organization) psi-mi:"MI:0469"(intact) crc64:53D15B8857A534E5 - figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 rogid:cUTmFkcG9XK4BwQ2VebK5tm10Dw559292 intact-crc:66E254ED08416928|rigid:IX6SFE4P9zhDDN0qIV6FSeB/BXY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02795 uniprotkb:P38264 intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340716|imex:IM-14275-2435 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N psi-mi:"MI:0469"(intact) crc64:53D15B8857A534E5 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 intact-crc:4AE05C657A0E74FE|rigid:b7AhhbqfqKc0E+K9OPkZq9VKSuI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02795 uniprotkb:P38353 intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W intact:EBI-18175|uniprotkb:D6VQS8|ensemblfungi:YBR283C psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:ssh1_yeast(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:Ssh1 complex subunit alpha(gene name synonym)|uniprotkb:Ssh1 complex subunit SSH1(gene name synonym)|uniprotkb:YBR2020(orf name)|uniprotkb:YBR283C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340727|imex:IM-14275-2436 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N refseq:NP_009842.1|sgd:S000000487|ensemblfungi:YBR283C(gene)|ensemblfungi:YBR283C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:2WW9|rcsb pdb:2WWA|dip:DIP-4962N|mint:P38353 psi-mi:"MI:0469"(intact) crc64:53D15B8857A534E5 crc64:48267EEA3E0191BD figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 rogid:76wvZIdv7W5BQn6wI+sHOGQAyuc559292 intact-crc:32AC3D7A45A18AE1|rigid:XMWh5YIG88AoPHpfGZxpRHrlw9o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02795 uniprotkb:P38694 intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W intact:EBI-24511|uniprotkb:D3DKY6|ensemblfungi:YHR039C psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:msc7_yeast(display_long)|uniprotkb:MSC7(gene name)|psi-mi:MSC7(display_short)|uniprotkb:Meiotic sister-chromatid recombination protein 7(gene name synonym)|uniprotkb:YHR039C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340738|imex:IM-14275-2437 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N refseq:NP_011904.1|sgd:S000001081|dip:DIP-1878N|mint:P38694|ensemblfungi:YHR039C(gene)|ensemblfungi:YHR039C_mRNA(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007131"(reciprocal meiotic recombination)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510 psi-mi:"MI:0469"(intact) crc64:53D15B8857A534E5 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 rogid:p2xtb6/xYI/jfPNtO6JRZs+5t6I559292 intact-crc:B672D86540C52113|rigid:gE1vzkc79IgpepCMljBuV8gmDrM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38993 uniprotkb:Q02795 intact:EBI-6876|uniprotkb:D6VZN2|ensemblfungi:YMR058W intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W psi-mi:fet3_yeast(display_long)|uniprotkb:YM9796.11(orf name)|uniprotkb:YMR058W(locus name)|uniprotkb:FET3(gene name)|psi-mi:FET3(display_short) psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340749|imex:IM-14275-2438 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013774.1|sgd:S000004662|mint:P38993|dip:DIP-5314N|ensemblfungi:YMR058W(gene)|ensemblfungi:YMR058W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0010106"(cellular response to iron ion starvation)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0033215"(reductive iron assimilation)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0046688"(response to copper ion)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR001117(Multicopper oxidase, type 1)|interpro:IPR002355(Multicopper oxidase, copper-binding site)|interpro:IPR008972(Cupredoxin)|interpro:IPR011706(Multicopper oxidase, type 2)|interpro:IPR011707(Multicopper oxidase, type 3)|interpro:IPR033138|interpro:IPR044130|rcsb pdb:1ZPU ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N psi-mi:"MI:0469"(intact) crc64:71CB4352B87746E6 crc64:53D15B8857A534E5 figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:yagULld2pZWL/KMb7zOTq7s2emM559292 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 intact-crc:BE8725AA7293317D|rigid:0Sn9LXed2dAcKrHuoBYI2C5bV10 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40350 uniprotkb:Q02795 intact:EBI-2470|uniprotkb:D6W3E3|ensemblfungi:YPL227C intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W psi-mi:alg5_yeast(display_long)|uniprotkb:ALG5(gene name)|psi-mi:ALG5(display_short)|uniprotkb:YPL227C(locus name)|uniprotkb:P1437(orf name)|uniprotkb:Asparagine-linked glycosylation protein 5(gene name synonym) psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340760|imex:IM-14275-2439 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015097.1|sgd:S000006148|dip:DIP-5651N|mint:P40350|ensemblfungi:YPL227C(gene)|ensemblfungi:YPL227C_mRNA(transcript)|go:"GO:0004581"(dolichyl-phosphate beta-glucosyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR035518|reactome:R-SCE-480985 ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N psi-mi:"MI:0469"(intact) - crc64:53D15B8857A534E5 figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aKi97cbwqo7kNWhtRyzG3UOLH4U559292 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 intact-crc:A0686C23A52B07D3|rigid:/2RNyZx3TzSPXcaIuLyE8WfazTo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40471 uniprotkb:Q02795 intact:EBI-25213|uniprotkb:D6VVG3|ensemblfungi:YIL124W intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W psi-mi:ayr1_yeast(display_long)|uniprotkb:AYR1(gene name)|psi-mi:AYR1(display_short)|uniprotkb:Acylglycerone-phosphate reductase(gene name synonym)|uniprotkb:1-acyl DHAP reductase(gene name synonym)|uniprotkb:Acyl/alkyl DHAP reductase(gene name synonym)|uniprotkb:GBG1(gene name synonym)|uniprotkb:Triacylglycerol lipase AYR1(gene name synonym)|uniprotkb:YIL124W(locus name) psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340771|imex:IM-14275-2440 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001386|refseq:NP_012142.3|mint:P40471|dip:DIP-4614N|ensemblfungi:YIL124W(gene)|ensemblfungi:YIL124W_mRNA(transcript)|go:"GO:0000140"(acylglycerone-phosphate reductase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0102566"(1-acyl dihydroxyacetone phosphate reductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291 ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N psi-mi:"MI:0469"(intact) crc64:B614C0E0B1FB0CE0 crc64:53D15B8857A534E5 figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WE4RmSXARj683MNUEsYGLis36Xo559292 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 intact-crc:C723EA9711375ECD|rigid:na+7MqTceWKNJNcl531zdbs862w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02795 uniprotkb:P40540 intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340782|imex:IM-14275-2441 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) crc64:53D15B8857A534E5 crc64:6DBEEEE7722203B0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 intact-crc:B968F8F3A18DF15E|rigid:X+QZb6XNW5WvTF+fE48mlRUvWFc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40582 uniprotkb:Q02795 intact:EBI-7941|uniprotkb:D6VVW9|ensemblfungi:YIR038C intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W psi-mi:gst1_yeast(display_long)|uniprotkb:YIR038C(locus name)|uniprotkb:GTT1(gene name)|psi-mi:GTT1(display_short)|uniprotkb:GST-I(gene name synonym) psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340793|imex:IM-14275-2442 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012304.1|sgd:S000001477|mint:P40582|dip:DIP-2103N|ensemblfungi:YIR038C(gene)|ensemblfungi:YIR038C_mRNA(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010731"(protein glutathionylation)|go:"GO:0071944"(cell periphery)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079 ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N psi-mi:"MI:0469"(intact) crc64:3C07D40D29F60DFF crc64:53D15B8857A534E5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+bqzHpsoLw4j2qQBzHbkfldR5OU559292 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 intact-crc:ADE4F8FAEC60EB79|rigid:OqvMbAvIEWrEjj/Ldt0qMbCbCs8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47155 uniprotkb:Q02795 intact:EBI-2051644|uniprotkb:D6VWT7|ensemblfungi:YJR118C intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W psi-mi:ilm1_yeast(display_long)|uniprotkb:Increased loss of mitochondrial DNA protein 1(gene name synonym)|uniprotkb:J2033(orf name)|uniprotkb:ILM1(gene name)|psi-mi:ILM1(display_short)|uniprotkb:YJR118C(locus name) psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340804|imex:IM-14275-2443 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003879|interpro:IPR018815|refseq:NP_012652.3|mint:P47155|ensemblfungi:YJR118C(gene)|ensemblfungi:YJR118C_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane) ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N psi-mi:"MI:0469"(intact) - crc64:53D15B8857A534E5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BrQhbXGvUjNG6Bt5c0J7T8qzMeI559292 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 intact-crc:D94CF0C2EDBD9B58|rigid:5pygAMMseTc0tDc+sG8WEP6xHSM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02795 uniprotkb:P53388 intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340815|imex:IM-14275-2444 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) psi-mi:"MI:0469"(intact) crc64:53D15B8857A534E5 crc64:488A382656039D0B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 intact-crc:F839719A1C449B3B|rigid:GQ3STCanrgOc9dDAoOm01X1KMpw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02795 uniprotkb:P54837 intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340826|imex:IM-14275-2445 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:53D15B8857A534E5 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:58205687EDE0E5FB|rigid:hkvXCz08NaYF2i+xvjsPTgWV5Z8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02795 uniprotkb:Q02774 intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340837|imex:IM-14275-2446 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 psi-mi:"MI:0469"(intact) crc64:53D15B8857A534E5 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 intact-crc:2220A26032C46965|rigid:Z0TRcnPWq7RCyMRNkkRdn7hrtJw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02795 uniprotkb:Q02896 intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W intact:EBI-22203|uniprotkb:D6W3T0|ensemblfungi:YPL087W psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:ydc1_yeast(display_long)|uniprotkb:YDC1(gene name)|psi-mi:YDC1(display_short)|uniprotkb:Acyl-CoA-independent ceramide synthase(gene name synonym)|uniprotkb:LPG21W(orf name)|uniprotkb:YPL087W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340848|imex:IM-14275-2447 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N refseq:NP_015238.1|sgd:S000006008|dip:DIP-7600N|mint:Q02896|ensemblfungi:YPL087W(gene)|ensemblfungi:YPL087W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046514"(ceramide catabolic process)|go:"GO:0070774"(phytoceramidase activity)|go:"GO:0071633"(dihydroceramidase activity)|interpro:IPR008901(Alkaline phytoceramidase)|reactome:R-SCE-1660661 psi-mi:"MI:0469"(intact) crc64:53D15B8857A534E5 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 rogid:UjLo2FMUWJPaHBDIYPjWZbqpk98559292 intact-crc:2C5826D1A96B28A8|rigid:XGjLFful4qurK5YuaV97hd1ZdoU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04969 uniprotkb:Q02795 intact:EBI-27827|uniprotkb:D6VZB9|ensemblfungi:YML055W intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W psi-mi:spc2_yeast(display_long)|uniprotkb:YML055W(locus name)|uniprotkb:YM9958.07(orf name)|uniprotkb:SPC2(gene name)|psi-mi:SPC2(display_short)|uniprotkb:SPY1(gene name synonym)|uniprotkb:Microsomal signal peptidase subunit 2(gene name synonym) psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340859|imex:IM-14275-2448 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013657.1|sgd:S000004519|dip:DIP-4540N|mint:Q04969|ensemblfungi:YML055W(gene)|ensemblfungi:YML055W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit) ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N psi-mi:"MI:0469"(intact) - crc64:53D15B8857A534E5 figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZXf9rPA3/ryPnDqI4JGp0VMNMe4559292 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 intact-crc:2D0CC3D221CEDFE0|rigid:monSs4pigrcNDow3Nb9UVYn411k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02795 uniprotkb:Q05359 intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340870|imex:IM-14275-2449 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:53D15B8857A534E5 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 intact-crc:4579C9FABDD6816D|rigid:UKvL39BcoNuCTGG2Mgo1pQdEAVQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06144 uniprotkb:Q02795 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340881|imex:IM-14275-2450 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N psi-mi:"MI:0469"(intact) crc64:2F474503CAB7C195 crc64:53D15B8857A534E5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 intact-crc:06D042ECDB258115|rigid:qW6DXFgsf5uTz6ijbnO++0QEDSc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08926 uniprotkb:Q02795 intact:EBI-2044051|uniprotkb:D6W3I3|ensemblfungi:YPL186C intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W psi-mi:uip4_yeast(display_long)|uniprotkb:YPL186C(locus name)|uniprotkb:UIP4(gene name)|psi-mi:UIP4(display_short) psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340892|imex:IM-14275-2451 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006107|refseq:NP_015138.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold)|mint:Q08926|ensemblfungi:YPL186C(gene)|ensemblfungi:YPL186C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane) ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N psi-mi:"MI:0469"(intact) - crc64:53D15B8857A534E5 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jZmXJYN6MQPlKDZXQnkU2tSI7vM559292 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 intact-crc:489DD10E4343CE28|rigid:r/cE5Wccc+/iz5gTwn9NKVkZNZw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12127 uniprotkb:Q02795 intact:EBI-5303|uniprotkb:D6VYB0|ensemblfungi:YLR110C intact:EBI-12666|uniprotkb:D6VZX1|ensemblfungi:YMR149W psi-mi:ccw12_yeast(display_long)|uniprotkb:CCW12(gene name)|psi-mi:CCW12(display_short)|uniprotkb:YLR110C(locus name)|uniprotkb:L9354.7(orf name)|uniprotkb:Protein Alpha0.6(gene name synonym) psi-mi:ostd_yeast(display_long)|uniprotkb:SWP1(gene name)|psi-mi:SWP1(display_short)|uniprotkb:YMR149W(locus name)|uniprotkb:YM9375.19(orf name)|uniprotkb:Oligosaccharyl transferase subunit delta(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340903|imex:IM-14275-2452 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004100|refseq:NP_013211.1|dip:DIP-4570N|mint:Q12127|ensemblfungi:YLR110C(gene)|ensemblfungi:YLR110C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000752"(agglutination involved in conjugation with cellular fusion)|go:"GO:0005199"(structural constituent of cell wall)|go:"GO:0005576"(extracellular region)|go:"GO:0005934"(cellular bud tip)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip)|go:"GO:0071944"(cell periphery)|interpro:IPR025928 ensemblfungi:YMR149W(gene)|ensemblfungi:YMR149W_mRNA(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|rcsb pdb:6C26|rcsb pdb:6EZN|refseq:NP_013869.1|sgd:S000004757|mint:Q02795|dip:DIP-2460N psi-mi:"MI:0469"(intact) - crc64:53D15B8857A534E5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:a43bKccHJ97vpmespaaZH0ADZ8U559292 rogid:aiEsA1BDDI/H1075xxqRHLV+R4Y559292 intact-crc:1EC83393DA70C99C|rigid:wOpAcu5bclpCk1FOGbBETTwMy6c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02796 uniprotkb:Q8TGU5 intact:EBI-30514|uniprotkb:Q6Q5I8|uniprotkb:D6W3V9|ensemblfungi:YPL055C intact:EBI-2042814|uniprotkb:D6VQU1|ensemblfungi:YBR296C-A psi-mi:lge1_yeast(display_long)|uniprotkb:Large cells protein 1(gene name synonym)|uniprotkb:LGE1(gene name)|psi-mi:LGE1(display_short)|uniprotkb:YPL055C(locus name) psi-mi:yb296_yeast(display_long)|uniprotkb:YBR296C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340914|imex:IM-14275-2453 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005976|refseq:NP_015270.1|dip:DIP-6470N|mint:Q02796|ensemblfungi:YPL055C(gene)|ensemblfungi:YPL055C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016571"(histone methylation)|go:"GO:0016574"(histone ubiquitination) sgd:S000028605|refseq:NP_878055.3|mint:Q8TGU5|ensemblfungi:YBR296C-A(gene)|ensemblfungi:YBR296C-A_mRNA(transcript)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity) psi-mi:"MI:0469"(intact) crc64:C3300ED944003F9D - figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4RSLriJ4AkHF3/kMyx+fiVXsAbk559292 rogid:DZubWD7lnwtea4Ne/bK1ITPFaJk559292 intact-crc:91A65AFA1A2BF620|rigid:B8zRNW6T4Q7j3Fri/kpq5gREFKM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02884 uniprotkb:P42935 intact:EBI-35277|uniprotkb:D6W3R5|ensemblfungi:YPL101W intact:EBI-23459|uniprotkb:D6VUY2|uniprotkb:E9P8V1|ensemblfungi:YGR200C psi-mi:elp4_yeast(display_long)|uniprotkb:ELP4(gene name)|psi-mi:ELP4(display_short)|uniprotkb:Gamma-toxin target 7(gene name synonym)|uniprotkb:HAT-associated protein 1(gene name synonym)|uniprotkb:YPL101W(locus name)|uniprotkb:HAP1(gene name synonym)|uniprotkb:TOT7(gene name synonym) psi-mi:elp2_yeast(display_long)|uniprotkb:YGR200C(locus name)|uniprotkb:G7725(orf name)|uniprotkb:ELP2(gene name)|psi-mi:ELP2(display_short)|uniprotkb:TOT2(gene name synonym)|uniprotkb:Gamma-toxin target 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340925|imex:IM-14275-2454 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015224.1|sgd:S000006022|mint:Q02884|dip:DIP-6718N|ensemblfungi:YPL101W(gene)|ensemblfungi:YPL101W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR008728(PAXNEB)|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS sgd:S000003432|refseq:NP_011716.3|dip:DIP-2386N|mint:P42935|ensemblfungi:YGR200C(gene)|ensemblfungi:YGR200C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008017"(microtubule binding)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0015031"(protein transport)|go:"GO:0032447"(protein urmylation)|go:"GO:0033588"(elongator holoenzyme complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037289|rcsb pdb:4XFV|rcsb pdb:5M2N|rcsb pdb:6QK7 psi-mi:"MI:0469"(intact) crc64:276F0D1538EAA8FA crc64:5371908FE2E6EC0D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:LLHmiDxhPIIxIElMn9yVWoFnY4Q559292 rogid:uBbnUH2xCo3Fu5LlxbrLxO43irk559292 intact-crc:CFAE7BED9D050FE8|rigid:j0+lfenLMLb/dlrbMdt175vZ1Ow false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02884 uniprotkb:Q02884 intact:EBI-35277|uniprotkb:D6W3R5|ensemblfungi:YPL101W intact:EBI-35277|uniprotkb:D6W3R5|ensemblfungi:YPL101W psi-mi:elp4_yeast(display_long)|uniprotkb:ELP4(gene name)|psi-mi:ELP4(display_short)|uniprotkb:Gamma-toxin target 7(gene name synonym)|uniprotkb:HAT-associated protein 1(gene name synonym)|uniprotkb:YPL101W(locus name)|uniprotkb:HAP1(gene name synonym)|uniprotkb:TOT7(gene name synonym) psi-mi:elp4_yeast(display_long)|uniprotkb:ELP4(gene name)|psi-mi:ELP4(display_short)|uniprotkb:Gamma-toxin target 7(gene name synonym)|uniprotkb:HAT-associated protein 1(gene name synonym)|uniprotkb:YPL101W(locus name)|uniprotkb:HAP1(gene name synonym)|uniprotkb:TOT7(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340936|imex:IM-14275-2455 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015224.1|sgd:S000006022|mint:Q02884|dip:DIP-6718N|ensemblfungi:YPL101W(gene)|ensemblfungi:YPL101W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR008728(PAXNEB)|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS refseq:NP_015224.1|sgd:S000006022|mint:Q02884|dip:DIP-6718N|ensemblfungi:YPL101W(gene)|ensemblfungi:YPL101W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR008728(PAXNEB)|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS psi-mi:"MI:0469"(intact) crc64:276F0D1538EAA8FA crc64:276F0D1538EAA8FA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:LLHmiDxhPIIxIElMn9yVWoFnY4Q559292 rogid:LLHmiDxhPIIxIElMn9yVWoFnY4Q559292 intact-crc:B3E3A6927D585825|rigid:rRMGvT1pyoORMpZlLR/Cb1JW7Hs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02884 uniprotkb:Q04868 intact:EBI-35277|uniprotkb:D6W3R5|ensemblfungi:YPL101W intact:EBI-27653|uniprotkb:D6W0D9|ensemblfungi:YMR312W psi-mi:elp4_yeast(display_long)|uniprotkb:ELP4(gene name)|psi-mi:ELP4(display_short)|uniprotkb:Gamma-toxin target 7(gene name synonym)|uniprotkb:HAT-associated protein 1(gene name synonym)|uniprotkb:YPL101W(locus name)|uniprotkb:HAP1(gene name synonym)|uniprotkb:TOT7(gene name synonym) psi-mi:elp6_yeast(display_long)|uniprotkb:YMR312W(locus name)|uniprotkb:YM9924.04(orf name)|uniprotkb:ELP6(gene name)|psi-mi:ELP6(display_short)|uniprotkb:HAP3(gene name synonym)|uniprotkb:TOT6(gene name synonym)|uniprotkb:Gamma-toxin target 6(gene name synonym)|uniprotkb:HAT-associated protein 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340947|imex:IM-14275-2456 author score:87.56 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015224.1|sgd:S000006022|mint:Q02884|dip:DIP-6718N|ensemblfungi:YPL101W(gene)|ensemblfungi:YPL101W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR008728(PAXNEB)|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS refseq:NP_014043.1|sgd:S000004929|dip:DIP-1966N|mint:Q04868|ensemblfungi:YMR312W(gene)|ensemblfungi:YMR312W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032447"(protein urmylation)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR018627|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS psi-mi:"MI:0469"(intact) crc64:276F0D1538EAA8FA crc64:1A5062465AF67F47 figure legend:tables S3 and S4|author-confidence:87.56|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:LLHmiDxhPIIxIElMn9yVWoFnY4Q559292 rogid:Nyp6/02bMFUoG//crZCg98Eepc8559292 intact-crc:AC75CDE9BEC32C3A|rigid:BTQ+2isArwCK2AF7MNUKyS7m5cU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02884 uniprotkb:Q06706 intact:EBI-35277|uniprotkb:D6W3R5|ensemblfungi:YPL101W intact:EBI-9068|uniprotkb:O00036|ensemblfungi:YLR384C|uniprotkb:D6VZ19 psi-mi:elp4_yeast(display_long)|uniprotkb:ELP4(gene name)|psi-mi:ELP4(display_short)|uniprotkb:Gamma-toxin target 7(gene name synonym)|uniprotkb:HAT-associated protein 1(gene name synonym)|uniprotkb:YPL101W(locus name)|uniprotkb:HAP1(gene name synonym)|uniprotkb:TOT7(gene name synonym) psi-mi:elp1_yeast(display_long)|uniprotkb:IKI3(gene name)|psi-mi:IKI3(display_short)|uniprotkb:YLR384C(locus name)|uniprotkb:L3502.7(orf name)|uniprotkb:ELP1(gene name synonym)|uniprotkb:TOT1(gene name synonym)|uniprotkb:Protein IKI3(gene name synonym)|uniprotkb:Gamma-toxin target 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340958|imex:IM-14275-2457 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015224.1|sgd:S000006022|mint:Q02884|dip:DIP-6718N|ensemblfungi:YPL101W(gene)|ensemblfungi:YPL101W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR008728(PAXNEB)|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS ensemblfungi:YLR384C(gene)|ensemblfungi:YLR384C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002926"(tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015031"(protein transport)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR006849(IKI3)|rcsb pdb:5CQS|rcsb pdb:6QK7|refseq:NP_013488.3|sgd:S000004376|dip:DIP-2384N|mint:Q06706 psi-mi:"MI:0469"(intact) crc64:276F0D1538EAA8FA crc64:7AEB1C0BA99282F6 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:LLHmiDxhPIIxIElMn9yVWoFnY4Q559292 rogid:EnFV08kc3WWB6YjyTKs7hSDvjPA559292 intact-crc:2EAD5E1E8B700886|rigid:QKgyDLNtSpViqhfpAZHN/D0INXU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38142 uniprotkb:Q02896 intact:EBI-21079|uniprotkb:D6VQN7|intact:EBI-2347460|uniprotkb:Q6B2Y5|ensemblfungi:YBR241C intact:EBI-22203|uniprotkb:D6W3T0|ensemblfungi:YPL087W psi-mi:yb91_yeast(display_long)|uniprotkb:YBR1625(orf name)|uniprotkb:YBR241C(locus name) psi-mi:ydc1_yeast(display_long)|uniprotkb:YDC1(gene name)|psi-mi:YDC1(display_short)|uniprotkb:Acyl-CoA-independent ceramide synthase(gene name synonym)|uniprotkb:LPG21W(orf name)|uniprotkb:YPL087W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340969|imex:IM-14275-2458 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009800.1|sgd:S000000445|mint:P38142|dip:DIP-5363N|ensemblfungi:YBR241C(gene)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|reactome:R-SCE-189200|reactome:R-SCE-196836|reactome:R-SCE-422356|reactome:R-SCE-5653890|reactome:R-SCE-6798695|reactome:R-SCE-8981373|ensemblfungi:YBR241C_mRNA(transcript) refseq:NP_015238.1|sgd:S000006008|dip:DIP-7600N|mint:Q02896|ensemblfungi:YPL087W(gene)|ensemblfungi:YPL087W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046514"(ceramide catabolic process)|go:"GO:0070774"(phytoceramidase activity)|go:"GO:0071633"(dihydroceramidase activity)|interpro:IPR008901(Alkaline phytoceramidase)|reactome:R-SCE-1660661 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:B0qgnhfd17hrDGLrJ21KY/FCzTQ559292 rogid:UjLo2FMUWJPaHBDIYPjWZbqpk98559292 intact-crc:37E48453F293255A|rigid:H24ytSOxPhentKim+98K5WTn3dU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40350 uniprotkb:Q02896 intact:EBI-2470|uniprotkb:D6W3E3|ensemblfungi:YPL227C intact:EBI-22203|uniprotkb:D6W3T0|ensemblfungi:YPL087W psi-mi:alg5_yeast(display_long)|uniprotkb:ALG5(gene name)|psi-mi:ALG5(display_short)|uniprotkb:YPL227C(locus name)|uniprotkb:P1437(orf name)|uniprotkb:Asparagine-linked glycosylation protein 5(gene name synonym) psi-mi:ydc1_yeast(display_long)|uniprotkb:YDC1(gene name)|psi-mi:YDC1(display_short)|uniprotkb:Acyl-CoA-independent ceramide synthase(gene name synonym)|uniprotkb:LPG21W(orf name)|uniprotkb:YPL087W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340980|imex:IM-14275-2459 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015097.1|sgd:S000006148|dip:DIP-5651N|mint:P40350|ensemblfungi:YPL227C(gene)|ensemblfungi:YPL227C_mRNA(transcript)|go:"GO:0004581"(dolichyl-phosphate beta-glucosyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR035518|reactome:R-SCE-480985 refseq:NP_015238.1|sgd:S000006008|dip:DIP-7600N|mint:Q02896|ensemblfungi:YPL087W(gene)|ensemblfungi:YPL087W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046514"(ceramide catabolic process)|go:"GO:0070774"(phytoceramidase activity)|go:"GO:0071633"(dihydroceramidase activity)|interpro:IPR008901(Alkaline phytoceramidase)|reactome:R-SCE-1660661 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aKi97cbwqo7kNWhtRyzG3UOLH4U559292 rogid:UjLo2FMUWJPaHBDIYPjWZbqpk98559292 intact-crc:E69DC5DEABD43341|rigid:rXN4bsYxGMWzXY+yUF2V6TaTKaw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02896 uniprotkb:P53751 intact:EBI-22203|uniprotkb:D6W3T0|ensemblfungi:YPL087W intact:EBI-28557|uniprotkb:D6W1P0|ensemblfungi:YNR065C psi-mi:ydc1_yeast(display_long)|uniprotkb:YDC1(gene name)|psi-mi:YDC1(display_short)|uniprotkb:Acyl-CoA-independent ceramide synthase(gene name synonym)|uniprotkb:LPG21W(orf name)|uniprotkb:YPL087W(locus name) psi-mi:yn94_yeast(display_long)|uniprotkb:N3539(orf name)|uniprotkb:YNR065C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6340991|imex:IM-14275-2460 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015238.1|sgd:S000006008|dip:DIP-7600N|mint:Q02896|ensemblfungi:YPL087W(gene)|ensemblfungi:YPL087W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046514"(ceramide catabolic process)|go:"GO:0070774"(phytoceramidase activity)|go:"GO:0071633"(dihydroceramidase activity)|interpro:IPR008901(Alkaline phytoceramidase)|reactome:R-SCE-1660661 refseq:NP_014463.1|sgd:S000005348|dip:DIP-4251N|mint:P53751|ensemblfungi:YNR065C(gene)|ensemblfungi:YNR065C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778 psi-mi:"MI:0469"(intact) - crc64:C0361878FE4DAB90 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UjLo2FMUWJPaHBDIYPjWZbqpk98559292 rogid:7iodiUQu3ZxDDC4KQlI3CoYD1IE559292 intact-crc:959308567F9F5326|rigid:DAcNpVvypz3J5iX+atru5Xrxi7A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02896 uniprotkb:P54837 intact:EBI-22203|uniprotkb:D6W3T0|ensemblfungi:YPL087W intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:ydc1_yeast(display_long)|uniprotkb:YDC1(gene name)|psi-mi:YDC1(display_short)|uniprotkb:Acyl-CoA-independent ceramide synthase(gene name synonym)|uniprotkb:LPG21W(orf name)|uniprotkb:YPL087W(locus name) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341002|imex:IM-14275-2461 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015238.1|sgd:S000006008|dip:DIP-7600N|mint:Q02896|ensemblfungi:YPL087W(gene)|ensemblfungi:YPL087W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046514"(ceramide catabolic process)|go:"GO:0070774"(phytoceramidase activity)|go:"GO:0071633"(dihydroceramidase activity)|interpro:IPR008901(Alkaline phytoceramidase)|reactome:R-SCE-1660661 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UjLo2FMUWJPaHBDIYPjWZbqpk98559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:1ED7280AEB3FD169|rigid:C/JyWI+xbflykhQJwNieRJkKfPI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12361 uniprotkb:Q02896 intact:EBI-7844|uniprotkb:D6VRV9|ensemblfungi:YDL035C intact:EBI-22203|uniprotkb:D6W3T0|ensemblfungi:YPL087W psi-mi:gpr1_yeast(display_long)|uniprotkb:GPR1(gene name)|psi-mi:GPR1(display_short)|uniprotkb:YDL035C(locus name) psi-mi:ydc1_yeast(display_long)|uniprotkb:YDC1(gene name)|psi-mi:YDC1(display_short)|uniprotkb:Acyl-CoA-independent ceramide synthase(gene name synonym)|uniprotkb:LPG21W(orf name)|uniprotkb:YPL087W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341013|imex:IM-14275-2462 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010249.1|sgd:S000002193|dip:DIP-8949N|mint:Q12361|ensemblfungi:YDL035C_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005536"(glucose binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0009731"(detection of sucrose stimulus)|go:"GO:0009745"(sucrose mediated signaling)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051594"(detection of glucose)|interpro:IPR022596|interpro:IPR023041|ensemblfungi:YDL035C(gene) refseq:NP_015238.1|sgd:S000006008|dip:DIP-7600N|mint:Q02896|ensemblfungi:YPL087W(gene)|ensemblfungi:YPL087W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046514"(ceramide catabolic process)|go:"GO:0070774"(phytoceramidase activity)|go:"GO:0071633"(dihydroceramidase activity)|interpro:IPR008901(Alkaline phytoceramidase)|reactome:R-SCE-1660661 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:OVr7tP9gvgHz57bZuzRIGH+VSPg559292 rogid:UjLo2FMUWJPaHBDIYPjWZbqpk98559292 intact-crc:B8757D144F22E791|rigid:g8MMDwSWR6muCV1qZNWpOb8JQww false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38874 uniprotkb:Q02908 intact:EBI-9061|ensemblfungi:YHR187W|uniprotkb:D3DLD5 intact:EBI-33957|uniprotkb:D6W3T1|ensemblfungi:YPL086C psi-mi:elp5_yeast(display_long)|uniprotkb:YHR187W(locus name)|uniprotkb:IKI1(gene name)|psi-mi:IKI1(display_short)|uniprotkb:ELP5(gene name synonym)|uniprotkb:HAP2(gene name synonym)|uniprotkb:TOT5(gene name synonym)|uniprotkb:Gamma-toxin target 5(gene name synonym)|uniprotkb:Protein IKI1(gene name synonym)|uniprotkb:HAT-associated protein 2(gene name synonym) psi-mi:elp3_yeast(display_long)|uniprotkb:ELP3(gene name)|psi-mi:ELP3(display_short)|uniprotkb:Gamma-toxin target 3(gene name synonym)|uniprotkb:HPA1(gene name synonym)|uniprotkb:TOT3(gene name synonym)|uniprotkb:"tRNA uridine(34) acetyltransferase"(gene name synonym)|uniprotkb:YPL086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341024|imex:IM-14275-2463 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001230|ensemblfungi:YHR187W(gene)|ensemblfungi:YHR187W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR019519|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS|refseq:NP_012057.3|dip:DIP-1967N|mint:P38874 refseq:NP_015239.1|sgd:S000006007|mint:Q02908|dip:DIP-2385N|ensemblfungi:YPL086C(gene)|ensemblfungi:YPL086C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002926"(tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0106261"("tRNA uridine(34) acetyltransferase activity")|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR032432|interpro:IPR034687|interpro:IPR039661|rcsb pdb:6QK7 psi-mi:"MI:0469"(intact) crc64:DFD93D7BA583E2F5 crc64:64EF8B42D3C3102E figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Xl/ausdL/d79OM78at6ZZldvBMg559292 rogid:otpUoDpD0rKMsXypvcWE4zc0uxI559292 intact-crc:D17EA5E697F7ECCE|rigid:d3eMsWija4lWtSHVnALMcSEkhck false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02908 uniprotkb:Q3E840 intact:EBI-33957|uniprotkb:D6W3T1|ensemblfungi:YPL086C intact:EBI-2055307|uniprotkb:D6VPT1|ensemblfungi:YBL071W-A psi-mi:elp3_yeast(display_long)|uniprotkb:ELP3(gene name)|psi-mi:ELP3(display_short)|uniprotkb:Gamma-toxin target 3(gene name synonym)|uniprotkb:HPA1(gene name synonym)|uniprotkb:TOT3(gene name synonym)|uniprotkb:"tRNA uridine(34) acetyltransferase"(gene name synonym)|uniprotkb:YPL086C(locus name) psi-mi:dph3_yeast(display_long)|uniprotkb:DPH3(gene name synonym)|uniprotkb:Kluyveromyces lactis toxin-insensitive protein 11(gene name synonym)|uniprotkb:YBL071W-A(locus name)|uniprotkb:KTI11(gene name)|psi-mi:KTI11(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341035|imex:IM-14275-2464 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015239.1|sgd:S000006007|mint:Q02908|dip:DIP-2385N|ensemblfungi:YPL086C(gene)|ensemblfungi:YPL086C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002926"(tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0106261"("tRNA uridine(34) acetyltransferase activity")|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR032432|interpro:IPR034687|interpro:IPR039661|rcsb pdb:6QK7 refseq:NP_660100.1|sgd:S000007587|dip:DIP-52225N|mint:Q3E840|ensemblfungi:YBL071W-A(gene)|ensemblfungi:YBL071W-A_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016730"(oxidoreductase activity, acting on iron-sulfur proteins as donors)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|interpro:IPR007872(Zinc finger, DPH-type)|interpro:IPR036671|interpro:IPR044248|rcsb pdb:1YOP|rcsb pdb:1YWS|rcsb pdb:4D4O|rcsb pdb:4D4P|rcsb pdb:4X33|rcsb pdb:5AX2|reactome:R-SCE-5358493 psi-mi:"MI:0469"(intact) crc64:64EF8B42D3C3102E crc64:8B27A307831B0ECE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:otpUoDpD0rKMsXypvcWE4zc0uxI559292 rogid:GwQlZVh0IRJ/OMoCjHic//fuHZE559292 intact-crc:C34EF230657584EF|rigid:R1qdnLRK5awlPPXzuz4ne0f3Dg4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02959 uniprotkb:Q02959 intact:EBI-8484|uniprotkb:D6W3Q2|ensemblfungi:YPL116W intact:EBI-8484|uniprotkb:D6W3Q2|ensemblfungi:YPL116W psi-mi:hos3_yeast(display_long)|uniprotkb:LPH11W(orf name)|uniprotkb:YPL116W(locus name)|uniprotkb:HOS3(gene name)|psi-mi:HOS3(display_short) psi-mi:hos3_yeast(display_long)|uniprotkb:LPH11W(orf name)|uniprotkb:YPL116W(locus name)|uniprotkb:HOS3(gene name)|psi-mi:HOS3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341046|imex:IM-14275-2465 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015209.1|sgd:S000006037|dip:DIP-8047N|mint:Q02959|ensemblfungi:YPL116W(gene)|ensemblfungi:YPL116W_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016575"(histone deacetylation)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138 refseq:NP_015209.1|sgd:S000006037|dip:DIP-8047N|mint:Q02959|ensemblfungi:YPL116W(gene)|ensemblfungi:YPL116W_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016575"(histone deacetylation)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138 psi-mi:"MI:0469"(intact) crc64:F2B5D09E87B097E5 crc64:F2B5D09E87B097E5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ykbhTSaTI6X7Yq1I80wWzvb2sVk559292 rogid:ykbhTSaTI6X7Yq1I80wWzvb2sVk559292 intact-crc:44F973E9F490FABC|rigid:oTdsMDYrFUgE+y/DgzQ8kv2jN70 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28795 uniprotkb:Q02969 intact:EBI-13164|uniprotkb:D6VSW1|ensemblfungi:YDR329C intact:EBI-37452|uniprotkb:Q6B2A9|uniprotkb:D6W3Q5|ensemblfungi:YPL112C psi-mi:pex3_yeast(display_long)|uniprotkb:PEX3(gene name)|psi-mi:PEX3(display_short)|uniprotkb:PAS3(gene name synonym)|uniprotkb:YDR329C(locus name)|uniprotkb:D9798.15(orf name)|uniprotkb:Peroxin-3(gene name synonym) psi-mi:pex25_yeast(display_long)|uniprotkb:YPL112C(locus name)|uniprotkb:PEX25(gene name)|psi-mi:PEX25(display_short)|uniprotkb:Peroxin-25(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341057|imex:IM-14275-2466 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002737|refseq:NP_010616.3|mint:P28795|dip:DIP-2477N|ensemblfungi:YDR329C(gene)|ensemblfungi:YDR329C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0045033"(peroxisome inheritance)|go:"GO:0045046"(protein import into peroxisome membrane)|interpro:IPR006966(Peroxin-3)|reactome:R-SCE-1369062|reactome:R-SCE-9603798 sgd:S000006033|refseq:NP_015213.1|dip:DIP-5292N|mint:Q02969|ensemblfungi:YPL112C(gene)|ensemblfungi:YPL112C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016559"(peroxisome fission)|go:"GO:0044375"(regulation of peroxisome size)|interpro:IPR008733(Peroxisomal biogenesis factor 11) psi-mi:"MI:0469"(intact) crc64:3CDC1D036DF0D0F9 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YcXHJijTXVH0oLXYmqsvIT/OeV4559292 rogid:42Jce4KR0S5WehK1GVfqhG+Cqbo559292 intact-crc:E002E91184F8132A|rigid:RkjHC3sHIXRvvhQQYa3JsBq5uLg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02969 uniprotkb:Q02969 intact:EBI-37452|uniprotkb:Q6B2A9|uniprotkb:D6W3Q5|ensemblfungi:YPL112C intact:EBI-37452|uniprotkb:Q6B2A9|uniprotkb:D6W3Q5|ensemblfungi:YPL112C psi-mi:pex25_yeast(display_long)|uniprotkb:YPL112C(locus name)|uniprotkb:PEX25(gene name)|psi-mi:PEX25(display_short)|uniprotkb:Peroxin-25(gene name synonym) psi-mi:pex25_yeast(display_long)|uniprotkb:YPL112C(locus name)|uniprotkb:PEX25(gene name)|psi-mi:PEX25(display_short)|uniprotkb:Peroxin-25(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341068|imex:IM-14275-2467 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006033|refseq:NP_015213.1|dip:DIP-5292N|mint:Q02969|ensemblfungi:YPL112C(gene)|ensemblfungi:YPL112C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016559"(peroxisome fission)|go:"GO:0044375"(regulation of peroxisome size)|interpro:IPR008733(Peroxisomal biogenesis factor 11) sgd:S000006033|refseq:NP_015213.1|dip:DIP-5292N|mint:Q02969|ensemblfungi:YPL112C(gene)|ensemblfungi:YPL112C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016559"(peroxisome fission)|go:"GO:0044375"(regulation of peroxisome size)|interpro:IPR008733(Peroxisomal biogenesis factor 11) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:42Jce4KR0S5WehK1GVfqhG+Cqbo559292 rogid:42Jce4KR0S5WehK1GVfqhG+Cqbo559292 intact-crc:66BAB8F493396CF6|rigid:2HdDA4ZBVVdvSaMaHHRG6HEMBvs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07418 uniprotkb:Q02969 intact:EBI-292|uniprotkb:D6VRT2|ensemblfungi:YDL065C intact:EBI-37452|uniprotkb:Q6B2A9|uniprotkb:D6W3Q5|ensemblfungi:YPL112C psi-mi:pex19_yeast(display_long)|uniprotkb:PEX19(gene name)|psi-mi:PEX19(display_short)|uniprotkb:PAS12(gene name synonym)|uniprotkb:YDL065C(locus name)|uniprotkb:Peroxin-19(gene name synonym)|uniprotkb:D2528(orf name) psi-mi:pex25_yeast(display_long)|uniprotkb:YPL112C(locus name)|uniprotkb:PEX25(gene name)|psi-mi:PEX25(display_short)|uniprotkb:Peroxin-25(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341079|imex:IM-14275-2468 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010218.2|sgd:S000002223|dip:DIP-1563N|mint:Q07418|ensemblfungi:YDL065C(gene)|ensemblfungi:YDL065C_mRNA(transcript)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0033328"(peroxisome membrane targeting sequence binding)|go:"GO:0045033"(peroxisome inheritance)|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0050821"(protein stabilization)|go:"GO:1990415"|interpro:IPR006708(Pex19 protein)|interpro:IPR038322|reactome:R-SCE-1369062|reactome:R-SCE-9603798 sgd:S000006033|refseq:NP_015213.1|dip:DIP-5292N|mint:Q02969|ensemblfungi:YPL112C(gene)|ensemblfungi:YPL112C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016559"(peroxisome fission)|go:"GO:0044375"(regulation of peroxisome size)|interpro:IPR008733(Peroxisomal biogenesis factor 11) psi-mi:"MI:0469"(intact) crc64:B2FDE24970443D2A - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:u/Q3DGHpQR712xEWNu1B/m5V72I559292 rogid:42Jce4KR0S5WehK1GVfqhG+Cqbo559292 intact-crc:864CD737679CDC0C|rigid:D/+3Tv4goZ9zb86bXSI8poDkPnw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02969 uniprotkb:Q12462 intact:EBI-37452|uniprotkb:Q6B2A9|uniprotkb:D6W3Q5|ensemblfungi:YPL112C intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C psi-mi:pex25_yeast(display_long)|uniprotkb:YPL112C(locus name)|uniprotkb:PEX25(gene name)|psi-mi:PEX25(display_short)|uniprotkb:Peroxin-25(gene name synonym) psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341090|imex:IM-14275-2469 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006033|refseq:NP_015213.1|dip:DIP-5292N|mint:Q02969|ensemblfungi:YPL112C(gene)|ensemblfungi:YPL112C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016559"(peroxisome fission)|go:"GO:0044375"(regulation of peroxisome size)|interpro:IPR008733(Peroxisomal biogenesis factor 11) refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:42Jce4KR0S5WehK1GVfqhG+Cqbo559292 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 intact-crc:02C89F6BF3B1EA0D|rigid:ubKdc5UTOGw0xiOa+L9NMfVWuQA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03029 uniprotkb:Q03944 intact:EBI-34162|uniprotkb:D6W3N7|ensemblfungi:YPL130W intact:EBI-30418|uniprotkb:D6VSI2|ensemblfungi:YDR200C psi-mi:spo19_yeast(display_long)|uniprotkb:SPO19(gene name)|psi-mi:SPO19(display_short)|uniprotkb:YPL130W(locus name) psi-mi:vps64_yeast(display_long)|uniprotkb:FAR9(gene name synonym)|uniprotkb:YD9346.10C(orf name)|uniprotkb:YDR200C(locus name)|uniprotkb:Factor arrest protein 9(gene name synonym)|uniprotkb:VPS64(gene name)|psi-mi:VPS64(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341101|imex:IM-14275-2470 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006051|refseq:NP_015195.1|mint:Q03029|dip:DIP-3997N|ensemblfungi:YPL130W(gene)|ensemblfungi:YPL130W_mRNA(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005628"(prospore membrane)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070583"(spore membrane bending pathway) sgd:S000002608|refseq:NP_010486.3|dip:DIP-1829N|mint:Q03944|ensemblfungi:YDR200C(gene)|ensemblfungi:YDR200C_mRNA(transcript)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031929"(TOR signaling)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|rcsb pdb:6A8W psi-mi:"MI:0469"(intact) - crc64:A22CEDD852FC421A figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:KKejAxK/6ZOcL+D9HHReNF4ao80559292 rogid:2jtSiV8992Ex17eb08gYie5/yzM559292 intact-crc:FEC166F3E10AC3A6|rigid:2e9L33kC41T+x/rXt+hMTMeGwEw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03148 uniprotkb:Q03148 intact:EBI-17618|uniprotkb:D6VZR9|ensemblfungi:YMR096W intact:EBI-17618|uniprotkb:D6VZR9|ensemblfungi:YMR096W psi-mi:snz1_yeast(display_long)|uniprotkb:SNZ1(gene name)|psi-mi:SNZ1(display_short)|uniprotkb:PDX1 homolog 1(gene name synonym)|uniprotkb:YM6543.03(orf name)|uniprotkb:YMR096W(locus name)|uniprotkb:p35(gene name synonym) psi-mi:snz1_yeast(display_long)|uniprotkb:SNZ1(gene name)|psi-mi:SNZ1(display_short)|uniprotkb:PDX1 homolog 1(gene name synonym)|uniprotkb:YM6543.03(orf name)|uniprotkb:YMR096W(locus name)|uniprotkb:p35(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341112|imex:IM-14275-2471 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013814.1|sgd:S000004702|ensemblfungi:YMR096W(gene)|ensemblfungi:YMR096W_mRNA(transcript)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0008615"(pyridoxine biosynthetic process)|go:"GO:0016843"(amine-lyase activity)|go:"GO:0036381"("pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity")|go:"GO:0042819"(vitamin B6 biosynthetic process)|go:"GO:0042823"(pyridoxal phosphate biosynthetic process)|go:"GO:1903600"(glutaminase complex)|interpro:IPR001852(Vitamin B6 biosynthesis protein)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR033755|rcsb pdb:3FEM|rcsb pdb:3O05|rcsb pdb:3O06|rcsb pdb:3O07|dip:DIP-1643N|mint:Q03148 refseq:NP_013814.1|sgd:S000004702|ensemblfungi:YMR096W(gene)|ensemblfungi:YMR096W_mRNA(transcript)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0008615"(pyridoxine biosynthetic process)|go:"GO:0016843"(amine-lyase activity)|go:"GO:0036381"("pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity")|go:"GO:0042819"(vitamin B6 biosynthetic process)|go:"GO:0042823"(pyridoxal phosphate biosynthetic process)|go:"GO:1903600"(glutaminase complex)|interpro:IPR001852(Vitamin B6 biosynthesis protein)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR033755|rcsb pdb:3FEM|rcsb pdb:3O05|rcsb pdb:3O06|rcsb pdb:3O07|dip:DIP-1643N|mint:Q03148 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4TUYaAPbqY9Bmq7HO8BmACRVMQM559292 rogid:4TUYaAPbqY9Bmq7HO8BmACRVMQM559292 intact-crc:3BCE8A36AE9A579A|rigid:zl8XkyK5FJ0JLkJY4L6OQE23Fwo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03390 uniprotkb:P39929 intact:EBI-2090142|uniprotkb:D6VTA9|ensemblfungi:YDR486C intact:EBI-17554|uniprotkb:D6VY27|ensemblfungi:YLR025W|uniprotkb:E9P8V6 psi-mi:vps60_yeast(display_long)|uniprotkb:Charged multivesicular body protein 5(gene name synonym)|uniprotkb:YDR486C(locus name)|uniprotkb:CHM5(gene name synonym)|uniprotkb:MOS10(gene name synonym)|uniprotkb:VPS60(gene name)|psi-mi:VPS60(display_short) psi-mi:snf7_yeast(display_long)|uniprotkb:SNF7(gene name)|psi-mi:SNF7(display_short)|uniprotkb:VPS32(gene name synonym)|uniprotkb:YLR025W(locus name)|uniprotkb:DID1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 32(gene name synonym)|uniprotkb:DOA4-independent degradation protein 1(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 7(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341123|imex:IM-14275-2472 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-8785N|sgd:S000002894|refseq:NP_010774.4|mint:Q03390|ensemblfungi:YDR486C(gene)|ensemblfungi:YDR486C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030447"(filamentous growth)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|interpro:IPR005024(Snf7)|rcsb pdb:2LUH|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328 refseq:NP_013125.1|sgd:S000004015|ensemblfungi:YLR025W(gene)|ensemblfungi:YLR025W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0071454"(cellular response to anoxia)|go:"GO:1904669"(ATP export)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|rcsb pdb:5FD7|rcsb pdb:5FD9|rcsb pdb:5T8L|rcsb pdb:5T8N|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1747N|mint:P39929 psi-mi:"MI:0469"(intact) - crc64:5241A18BB181F0C1 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:JJYURVH0yGW+NbEfToN2nhk7vvU559292 rogid:I8qBtNlqTjxLX1HginTOzM3o9oA559292 intact-crc:B0771032EC3617CD|rigid:xEAQf6AvaIdTjAUcHKct0hMU/Dk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03390 uniprotkb:Q03390 intact:EBI-2090142|uniprotkb:D6VTA9|ensemblfungi:YDR486C intact:EBI-2090142|uniprotkb:D6VTA9|ensemblfungi:YDR486C psi-mi:vps60_yeast(display_long)|uniprotkb:Charged multivesicular body protein 5(gene name synonym)|uniprotkb:YDR486C(locus name)|uniprotkb:CHM5(gene name synonym)|uniprotkb:MOS10(gene name synonym)|uniprotkb:VPS60(gene name)|psi-mi:VPS60(display_short) psi-mi:vps60_yeast(display_long)|uniprotkb:Charged multivesicular body protein 5(gene name synonym)|uniprotkb:YDR486C(locus name)|uniprotkb:CHM5(gene name synonym)|uniprotkb:MOS10(gene name synonym)|uniprotkb:VPS60(gene name)|psi-mi:VPS60(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341134|imex:IM-14275-2473 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-8785N|sgd:S000002894|refseq:NP_010774.4|mint:Q03390|ensemblfungi:YDR486C(gene)|ensemblfungi:YDR486C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030447"(filamentous growth)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|interpro:IPR005024(Snf7)|rcsb pdb:2LUH|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328 dip:DIP-8785N|sgd:S000002894|refseq:NP_010774.4|mint:Q03390|ensemblfungi:YDR486C(gene)|ensemblfungi:YDR486C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030447"(filamentous growth)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|interpro:IPR005024(Snf7)|rcsb pdb:2LUH|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:JJYURVH0yGW+NbEfToN2nhk7vvU559292 rogid:JJYURVH0yGW+NbEfToN2nhk7vvU559292 intact-crc:9A4B3B2EC08F82D8|rigid:yYLnHuHZFH8nV4mw6Y0udIau2GY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03390 uniprotkb:Q06263 intact:EBI-2090142|uniprotkb:D6VTA9|ensemblfungi:YDR486C intact:EBI-37098|uniprotkb:Q07057|uniprotkb:D6VYI5|ensemblfungi:YLR181C psi-mi:vps60_yeast(display_long)|uniprotkb:Charged multivesicular body protein 5(gene name synonym)|uniprotkb:YDR486C(locus name)|uniprotkb:CHM5(gene name synonym)|uniprotkb:MOS10(gene name synonym)|uniprotkb:VPS60(gene name)|psi-mi:VPS60(display_short) psi-mi:vta1_yeast(display_long)|uniprotkb:VTA1(gene name)|psi-mi:VTA1(display_short)|uniprotkb:YLR181C(locus name)|uniprotkb:VPS20-associated protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341145|imex:IM-14275-2474 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-8785N|sgd:S000002894|refseq:NP_010774.4|mint:Q03390|ensemblfungi:YDR486C(gene)|ensemblfungi:YDR486C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030447"(filamentous growth)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|interpro:IPR005024(Snf7)|rcsb pdb:2LUH|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328 refseq:NP_013282.1|sgd:S000004171|mint:Q06263|dip:DIP-4802N|ensemblfungi:YLR181C(gene)|ensemblfungi:YLR181C_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0006869"(lipid transport)|go:"GO:0015031"(protein transport)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR023175|interpro:IPR039431|interpro:IPR041212|interpro:IPR044538|rcsb pdb:2LUH|rcsb pdb:2RKK|rcsb pdb:2RKL|rcsb pdb:3MHV|rcsb pdb:5H7P|rcsb pdb:5UIE|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6OO2|reactome:R-SCE-917729 psi-mi:"MI:0469"(intact) - crc64:BB6E6975596C1674 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:JJYURVH0yGW+NbEfToN2nhk7vvU559292 rogid:X9sRQb1nZECFkdjvDUTjxEgokRM559292 intact-crc:C8F08AB43B44940A|rigid:0/x+AWlSOtTimGePNlX+nYn2+Sw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03435 uniprotkb:Q03435 intact:EBI-12010|ensemblfungi:YDL002C|uniprotkb:D6VRY6 intact:EBI-12010|ensemblfungi:YDL002C|uniprotkb:D6VRY6 psi-mi:nhp10_yeast(display_long)|uniprotkb:HMO2(gene name synonym)|uniprotkb:YD8119.05C(orf name)|uniprotkb:YDL002C(locus name)|uniprotkb:NHP10(gene name)|psi-mi:NHP10(display_short)|uniprotkb:High mobility group protein 2(gene name synonym) psi-mi:nhp10_yeast(display_long)|uniprotkb:HMO2(gene name synonym)|uniprotkb:YD8119.05C(orf name)|uniprotkb:YDL002C(locus name)|uniprotkb:NHP10(gene name)|psi-mi:NHP10(display_short)|uniprotkb:High mobility group protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341156|imex:IM-14275-2475 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDL002C(gene)|ensemblfungi:YDL002C_mRNA(transcript)|go:"GO:0000404"(heteroduplex DNA loop binding)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0031011"(Ino80 complex)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0045027"(DNA end binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030483|interpro:IPR036910|reactome:R-SCE-140342|reactome:R-SCE-5620971|reactome:R-SCE-5686938|reactome:R-SCE-6798695|refseq:NP_010282.3|sgd:S000002160|mint:Q03435|dip:DIP-1387N ensemblfungi:YDL002C(gene)|ensemblfungi:YDL002C_mRNA(transcript)|go:"GO:0000404"(heteroduplex DNA loop binding)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0031011"(Ino80 complex)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0045027"(DNA end binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030483|interpro:IPR036910|reactome:R-SCE-140342|reactome:R-SCE-5620971|reactome:R-SCE-5686938|reactome:R-SCE-6798695|refseq:NP_010282.3|sgd:S000002160|mint:Q03435|dip:DIP-1387N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:d80vaGqvQrja5QSpys5lAbGbZLU559292 rogid:d80vaGqvQrja5QSpys5lAbGbZLU559292 intact-crc:17A41FE65A2DE288|rigid:4M+QMBUotUnTXNStcFK/csQi+YI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03516 uniprotkb:P36027 intact:EBI-27593|ensemblfungi:YMR266W|uniprotkb:D6W092 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:rsn1_yeast(display_long)|uniprotkb:YMR266W(locus name)|uniprotkb:YM8156.08(orf name)|uniprotkb:RSN1(gene name)|psi-mi:RSN1(display_short)|uniprotkb:Rescuer of SRO7 at high Nacl protein 1(gene name synonym) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341167|imex:IM-14275-2476 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR266W(gene)|ensemblfungi:YMR266W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR003864(Protein of unknown function DUF221)|interpro:IPR022257|interpro:IPR027815|interpro:IPR032880|refseq:NP_013993.1|sgd:S000004879|dip:DIP-6549N|mint:Q03516 ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) crc64:F6F7BA2B3F3AD44B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oyJcJS+pUv9eWbLk5ImUT6Cfa1A559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:5160BD385F0C530C|rigid:ePlKVz286oKRmx7avTtIlo3CYNo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:Q03516 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-27593|ensemblfungi:YMR266W|uniprotkb:D6W092 psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:rsn1_yeast(display_long)|uniprotkb:YMR266W(locus name)|uniprotkb:YM8156.08(orf name)|uniprotkb:RSN1(gene name)|psi-mi:RSN1(display_short)|uniprotkb:Rescuer of SRO7 at high Nacl protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341178|imex:IM-14275-2477 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 ensemblfungi:YMR266W(gene)|ensemblfungi:YMR266W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR003864(Protein of unknown function DUF221)|interpro:IPR022257|interpro:IPR027815|interpro:IPR032880|refseq:NP_013993.1|sgd:S000004879|dip:DIP-6549N|mint:Q03516 psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 crc64:F6F7BA2B3F3AD44B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:oyJcJS+pUv9eWbLk5ImUT6Cfa1A559292 intact-crc:2DE8C916C249A573|rigid:YG2o2JIHxC8gj43UADMAiIqehbc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:Q03529 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-16747|ensemblfungi:YMR272C|uniprotkb:D6W098 psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:scs7_yeast(display_long)|uniprotkb:SCS7(gene name)|psi-mi:SCS7(display_short)|uniprotkb:FAH1(gene name synonym)|uniprotkb:YMR272C(locus name)|uniprotkb:YM8156.14C(orf name)|uniprotkb:Suppressor of calcium sensitivity 7(gene name synonym)|uniprotkb:4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Dihydroceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Sphingolipid alpha-hydroxylase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341189|imex:IM-14275-2478 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 ensemblfungi:YMR272C(gene)|ensemblfungi:YMR272C_mRNA(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0080132"(fatty acid alpha-hydroxylase activity)|go:"GO:0102771"(sphingolipid very long chain fatty acid alpha-hydroxylase activity)|rcsb pdb:4ZR0|rcsb pdb:4ZR1|reactome:R-SCE-1660661|refseq:NP_013999.1|sgd:S000004885|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR006694(Fatty acid hydroxylase)|interpro:IPR014430(Inositolphosphorylceramide-B hydroxylase)|mint:Q03529|interpro:IPR036400 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:M34W8LH4q+H1EOi7khg+f/TKtgQ559292 intact-crc:06DAC673EB5B901A|rigid:kTZkvT9xZQlUyG47fo17xvKG7Pk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03529 uniprotkb:P25361 intact:EBI-16747|ensemblfungi:YMR272C|uniprotkb:D6W098 intact:EBI-21909|uniprotkb:D6VR52|ensemblfungi:YCR043C psi-mi:scs7_yeast(display_long)|uniprotkb:SCS7(gene name)|psi-mi:SCS7(display_short)|uniprotkb:FAH1(gene name synonym)|uniprotkb:YMR272C(locus name)|uniprotkb:YM8156.14C(orf name)|uniprotkb:Suppressor of calcium sensitivity 7(gene name synonym)|uniprotkb:4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Dihydroceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Sphingolipid alpha-hydroxylase(gene name synonym) psi-mi:yct3_yeast(display_long)|uniprotkb:YCR43C(orf name)|uniprotkb:YCR725(orf name)|uniprotkb:YCR043C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341200|imex:IM-14275-2479 author score:99.26 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR272C(gene)|ensemblfungi:YMR272C_mRNA(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0080132"(fatty acid alpha-hydroxylase activity)|go:"GO:0102771"(sphingolipid very long chain fatty acid alpha-hydroxylase activity)|rcsb pdb:4ZR0|rcsb pdb:4ZR1|reactome:R-SCE-1660661|refseq:NP_013999.1|sgd:S000004885|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR006694(Fatty acid hydroxylase)|interpro:IPR014430(Inositolphosphorylceramide-B hydroxylase)|mint:Q03529|interpro:IPR036400 sgd:S000000639|refseq:NP_009972.1|mint:P25361|ensemblfungi:YCR043C(gene)|ensemblfungi:YCR043C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0043332"(mating projection tip) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.26|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:M34W8LH4q+H1EOi7khg+f/TKtgQ559292 rogid:bEMtsAa5vCsWqGOiXwBK40Pa0xQ559292 intact-crc:5069D1D11FE05B43|rigid:TBH8f6KZqj8XFv5xtOOnEuInteE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03529 uniprotkb:P36076 intact:EBI-16747|ensemblfungi:YMR272C|uniprotkb:D6W098 intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W psi-mi:scs7_yeast(display_long)|uniprotkb:SCS7(gene name)|psi-mi:SCS7(display_short)|uniprotkb:FAH1(gene name synonym)|uniprotkb:YMR272C(locus name)|uniprotkb:YM8156.14C(orf name)|uniprotkb:Suppressor of calcium sensitivity 7(gene name synonym)|uniprotkb:4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Dihydroceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Sphingolipid alpha-hydroxylase(gene name synonym) psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341211|imex:IM-14275-2480 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR272C(gene)|ensemblfungi:YMR272C_mRNA(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0080132"(fatty acid alpha-hydroxylase activity)|go:"GO:0102771"(sphingolipid very long chain fatty acid alpha-hydroxylase activity)|rcsb pdb:4ZR0|rcsb pdb:4ZR1|reactome:R-SCE-1660661|refseq:NP_013999.1|sgd:S000004885|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR006694(Fatty acid hydroxylase)|interpro:IPR014430(Inositolphosphorylceramide-B hydroxylase)|mint:Q03529|interpro:IPR036400 refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:M34W8LH4q+H1EOi7khg+f/TKtgQ559292 rogid:Li7vZOassm4PC5fW111/j5ivgEc559292 intact-crc:F2817AF2498C215C|rigid:WvrM0BReJk8IbLW4V4CLE5vZZiE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:Q03529 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-16747|ensemblfungi:YMR272C|uniprotkb:D6W098 psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:scs7_yeast(display_long)|uniprotkb:SCS7(gene name)|psi-mi:SCS7(display_short)|uniprotkb:FAH1(gene name synonym)|uniprotkb:YMR272C(locus name)|uniprotkb:YM8156.14C(orf name)|uniprotkb:Suppressor of calcium sensitivity 7(gene name synonym)|uniprotkb:4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Dihydroceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Sphingolipid alpha-hydroxylase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341222|imex:IM-14275-2481 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N ensemblfungi:YMR272C(gene)|ensemblfungi:YMR272C_mRNA(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0080132"(fatty acid alpha-hydroxylase activity)|go:"GO:0102771"(sphingolipid very long chain fatty acid alpha-hydroxylase activity)|rcsb pdb:4ZR0|rcsb pdb:4ZR1|reactome:R-SCE-1660661|refseq:NP_013999.1|sgd:S000004885|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR006694(Fatty acid hydroxylase)|interpro:IPR014430(Inositolphosphorylceramide-B hydroxylase)|mint:Q03529|interpro:IPR036400 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:M34W8LH4q+H1EOi7khg+f/TKtgQ559292 intact-crc:11CCC4A5367B2CD7|rigid:3QxXMnALy/GSz1JlRtdasGg2zJw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03529 uniprotkb:P38353 intact:EBI-16747|ensemblfungi:YMR272C|uniprotkb:D6W098 intact:EBI-18175|uniprotkb:D6VQS8|ensemblfungi:YBR283C psi-mi:scs7_yeast(display_long)|uniprotkb:SCS7(gene name)|psi-mi:SCS7(display_short)|uniprotkb:FAH1(gene name synonym)|uniprotkb:YMR272C(locus name)|uniprotkb:YM8156.14C(orf name)|uniprotkb:Suppressor of calcium sensitivity 7(gene name synonym)|uniprotkb:4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Dihydroceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Sphingolipid alpha-hydroxylase(gene name synonym) psi-mi:ssh1_yeast(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:Ssh1 complex subunit alpha(gene name synonym)|uniprotkb:Ssh1 complex subunit SSH1(gene name synonym)|uniprotkb:YBR2020(orf name)|uniprotkb:YBR283C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341233|imex:IM-14275-2482 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR272C(gene)|ensemblfungi:YMR272C_mRNA(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0080132"(fatty acid alpha-hydroxylase activity)|go:"GO:0102771"(sphingolipid very long chain fatty acid alpha-hydroxylase activity)|rcsb pdb:4ZR0|rcsb pdb:4ZR1|reactome:R-SCE-1660661|refseq:NP_013999.1|sgd:S000004885|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR006694(Fatty acid hydroxylase)|interpro:IPR014430(Inositolphosphorylceramide-B hydroxylase)|mint:Q03529|interpro:IPR036400 refseq:NP_009842.1|sgd:S000000487|ensemblfungi:YBR283C(gene)|ensemblfungi:YBR283C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:2WW9|rcsb pdb:2WWA|dip:DIP-4962N|mint:P38353 psi-mi:"MI:0469"(intact) - crc64:48267EEA3E0191BD figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:M34W8LH4q+H1EOi7khg+f/TKtgQ559292 rogid:76wvZIdv7W5BQn6wI+sHOGQAyuc559292 intact-crc:6983C1AA0864D2C8|rigid:qdpcHUiIfjsECPYT5V0Ug2NN7VE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38694 uniprotkb:Q03529 intact:EBI-24511|uniprotkb:D3DKY6|ensemblfungi:YHR039C intact:EBI-16747|ensemblfungi:YMR272C|uniprotkb:D6W098 psi-mi:msc7_yeast(display_long)|uniprotkb:MSC7(gene name)|psi-mi:MSC7(display_short)|uniprotkb:Meiotic sister-chromatid recombination protein 7(gene name synonym)|uniprotkb:YHR039C(locus name) psi-mi:scs7_yeast(display_long)|uniprotkb:SCS7(gene name)|psi-mi:SCS7(display_short)|uniprotkb:FAH1(gene name synonym)|uniprotkb:YMR272C(locus name)|uniprotkb:YM8156.14C(orf name)|uniprotkb:Suppressor of calcium sensitivity 7(gene name synonym)|uniprotkb:4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Dihydroceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Sphingolipid alpha-hydroxylase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341244|imex:IM-14275-2483 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011904.1|sgd:S000001081|dip:DIP-1878N|mint:P38694|ensemblfungi:YHR039C(gene)|ensemblfungi:YHR039C_mRNA(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007131"(reciprocal meiotic recombination)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510 ensemblfungi:YMR272C(gene)|ensemblfungi:YMR272C_mRNA(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0080132"(fatty acid alpha-hydroxylase activity)|go:"GO:0102771"(sphingolipid very long chain fatty acid alpha-hydroxylase activity)|rcsb pdb:4ZR0|rcsb pdb:4ZR1|reactome:R-SCE-1660661|refseq:NP_013999.1|sgd:S000004885|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR006694(Fatty acid hydroxylase)|interpro:IPR014430(Inositolphosphorylceramide-B hydroxylase)|mint:Q03529|interpro:IPR036400 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p2xtb6/xYI/jfPNtO6JRZs+5t6I559292 rogid:M34W8LH4q+H1EOi7khg+f/TKtgQ559292 intact-crc:ED5C94B50D00793A|rigid:rbwW2ZxoCZOPbrLfZlhkA1sPFj0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03529 uniprotkb:P40350 intact:EBI-16747|ensemblfungi:YMR272C|uniprotkb:D6W098 intact:EBI-2470|uniprotkb:D6W3E3|ensemblfungi:YPL227C psi-mi:scs7_yeast(display_long)|uniprotkb:SCS7(gene name)|psi-mi:SCS7(display_short)|uniprotkb:FAH1(gene name synonym)|uniprotkb:YMR272C(locus name)|uniprotkb:YM8156.14C(orf name)|uniprotkb:Suppressor of calcium sensitivity 7(gene name synonym)|uniprotkb:4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Dihydroceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Sphingolipid alpha-hydroxylase(gene name synonym) psi-mi:alg5_yeast(display_long)|uniprotkb:ALG5(gene name)|psi-mi:ALG5(display_short)|uniprotkb:YPL227C(locus name)|uniprotkb:P1437(orf name)|uniprotkb:Asparagine-linked glycosylation protein 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341255|imex:IM-14275-2484 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR272C(gene)|ensemblfungi:YMR272C_mRNA(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0080132"(fatty acid alpha-hydroxylase activity)|go:"GO:0102771"(sphingolipid very long chain fatty acid alpha-hydroxylase activity)|rcsb pdb:4ZR0|rcsb pdb:4ZR1|reactome:R-SCE-1660661|refseq:NP_013999.1|sgd:S000004885|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR006694(Fatty acid hydroxylase)|interpro:IPR014430(Inositolphosphorylceramide-B hydroxylase)|mint:Q03529|interpro:IPR036400 refseq:NP_015097.1|sgd:S000006148|dip:DIP-5651N|mint:P40350|ensemblfungi:YPL227C(gene)|ensemblfungi:YPL227C_mRNA(transcript)|go:"GO:0004581"(dolichyl-phosphate beta-glucosyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR035518|reactome:R-SCE-480985 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:M34W8LH4q+H1EOi7khg+f/TKtgQ559292 rogid:aKi97cbwqo7kNWhtRyzG3UOLH4U559292 intact-crc:FB4794E3E95E5FFA|rigid:cZPRQUOfe97aUXV3Jz9vmW5daRk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03529 uniprotkb:P40540 intact:EBI-16747|ensemblfungi:YMR272C|uniprotkb:D6W098 intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C psi-mi:scs7_yeast(display_long)|uniprotkb:SCS7(gene name)|psi-mi:SCS7(display_short)|uniprotkb:FAH1(gene name synonym)|uniprotkb:YMR272C(locus name)|uniprotkb:YM8156.14C(orf name)|uniprotkb:Suppressor of calcium sensitivity 7(gene name synonym)|uniprotkb:4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Dihydroceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Sphingolipid alpha-hydroxylase(gene name synonym) psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341266|imex:IM-14275-2485 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR272C(gene)|ensemblfungi:YMR272C_mRNA(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0080132"(fatty acid alpha-hydroxylase activity)|go:"GO:0102771"(sphingolipid very long chain fatty acid alpha-hydroxylase activity)|rcsb pdb:4ZR0|rcsb pdb:4ZR1|reactome:R-SCE-1660661|refseq:NP_013999.1|sgd:S000004885|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR006694(Fatty acid hydroxylase)|interpro:IPR014430(Inositolphosphorylceramide-B hydroxylase)|mint:Q03529|interpro:IPR036400 refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) - crc64:6DBEEEE7722203B0 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:M34W8LH4q+H1EOi7khg+f/TKtgQ559292 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 intact-crc:E249E353EDF8A977|rigid:XbRXCJlbW2GhjqE0klbMBX99iwU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53337 uniprotkb:Q03529 intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C intact:EBI-16747|ensemblfungi:YMR272C|uniprotkb:D6W098 psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:scs7_yeast(display_long)|uniprotkb:SCS7(gene name)|psi-mi:SCS7(display_short)|uniprotkb:FAH1(gene name synonym)|uniprotkb:YMR272C(locus name)|uniprotkb:YM8156.14C(orf name)|uniprotkb:Suppressor of calcium sensitivity 7(gene name synonym)|uniprotkb:4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Dihydroceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Sphingolipid alpha-hydroxylase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341277|imex:IM-14275-2486 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 ensemblfungi:YMR272C(gene)|ensemblfungi:YMR272C_mRNA(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0080132"(fatty acid alpha-hydroxylase activity)|go:"GO:0102771"(sphingolipid very long chain fatty acid alpha-hydroxylase activity)|rcsb pdb:4ZR0|rcsb pdb:4ZR1|reactome:R-SCE-1660661|refseq:NP_013999.1|sgd:S000004885|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR006694(Fatty acid hydroxylase)|interpro:IPR014430(Inositolphosphorylceramide-B hydroxylase)|mint:Q03529|interpro:IPR036400 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 rogid:M34W8LH4q+H1EOi7khg+f/TKtgQ559292 intact-crc:06BD8D70A00D8EA6|rigid:QBEOasSJ8Lym8GZCOHkdl/WeUrw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:Q03529 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-16747|ensemblfungi:YMR272C|uniprotkb:D6W098 psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:scs7_yeast(display_long)|uniprotkb:SCS7(gene name)|psi-mi:SCS7(display_short)|uniprotkb:FAH1(gene name synonym)|uniprotkb:YMR272C(locus name)|uniprotkb:YM8156.14C(orf name)|uniprotkb:Suppressor of calcium sensitivity 7(gene name synonym)|uniprotkb:4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Dihydroceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Sphingolipid alpha-hydroxylase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341288|imex:IM-14275-2487 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 ensemblfungi:YMR272C(gene)|ensemblfungi:YMR272C_mRNA(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0080132"(fatty acid alpha-hydroxylase activity)|go:"GO:0102771"(sphingolipid very long chain fatty acid alpha-hydroxylase activity)|rcsb pdb:4ZR0|rcsb pdb:4ZR1|reactome:R-SCE-1660661|refseq:NP_013999.1|sgd:S000004885|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR006694(Fatty acid hydroxylase)|interpro:IPR014430(Inositolphosphorylceramide-B hydroxylase)|mint:Q03529|interpro:IPR036400 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:M34W8LH4q+H1EOi7khg+f/TKtgQ559292 intact-crc:030CCE47A195BDD2|rigid:sKezAbUaOtSwn+hEy5szP8adIMs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:Q03529 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-16747|ensemblfungi:YMR272C|uniprotkb:D6W098 psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:scs7_yeast(display_long)|uniprotkb:SCS7(gene name)|psi-mi:SCS7(display_short)|uniprotkb:FAH1(gene name synonym)|uniprotkb:YMR272C(locus name)|uniprotkb:YM8156.14C(orf name)|uniprotkb:Suppressor of calcium sensitivity 7(gene name synonym)|uniprotkb:4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Dihydroceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Sphingolipid alpha-hydroxylase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341299|imex:IM-14275-2488 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 ensemblfungi:YMR272C(gene)|ensemblfungi:YMR272C_mRNA(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0080132"(fatty acid alpha-hydroxylase activity)|go:"GO:0102771"(sphingolipid very long chain fatty acid alpha-hydroxylase activity)|rcsb pdb:4ZR0|rcsb pdb:4ZR1|reactome:R-SCE-1660661|refseq:NP_013999.1|sgd:S000004885|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR006694(Fatty acid hydroxylase)|interpro:IPR014430(Inositolphosphorylceramide-B hydroxylase)|mint:Q03529|interpro:IPR036400 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:M34W8LH4q+H1EOi7khg+f/TKtgQ559292 intact-crc:83F597CC8BD91A51|rigid:ZuYqplMOMwHuoVOouGXDPw50pxY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03529 uniprotkb:Q06144 intact:EBI-16747|ensemblfungi:YMR272C|uniprotkb:D6W098 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:scs7_yeast(display_long)|uniprotkb:SCS7(gene name)|psi-mi:SCS7(display_short)|uniprotkb:FAH1(gene name synonym)|uniprotkb:YMR272C(locus name)|uniprotkb:YM8156.14C(orf name)|uniprotkb:Suppressor of calcium sensitivity 7(gene name synonym)|uniprotkb:4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Dihydroceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Sphingolipid alpha-hydroxylase(gene name synonym) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341310|imex:IM-14275-2489 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR272C(gene)|ensemblfungi:YMR272C_mRNA(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0080132"(fatty acid alpha-hydroxylase activity)|go:"GO:0102771"(sphingolipid very long chain fatty acid alpha-hydroxylase activity)|rcsb pdb:4ZR0|rcsb pdb:4ZR1|reactome:R-SCE-1660661|refseq:NP_013999.1|sgd:S000004885|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR006694(Fatty acid hydroxylase)|interpro:IPR014430(Inositolphosphorylceramide-B hydroxylase)|mint:Q03529|interpro:IPR036400 refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:2F474503CAB7C195 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:M34W8LH4q+H1EOi7khg+f/TKtgQ559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 intact-crc:C05B6FBAED2A1A29|rigid:+c5sdJeXgoPloTdXYWt4pgrYhUA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03529 uniprotkb:Q12043 intact:EBI-16747|ensemblfungi:YMR272C|uniprotkb:D6W098 intact:EBI-34845|uniprotkb:Q7LH13|uniprotkb:D6W2E4|ensemblfungi:YOR081C psi-mi:scs7_yeast(display_long)|uniprotkb:SCS7(gene name)|psi-mi:SCS7(display_short)|uniprotkb:FAH1(gene name synonym)|uniprotkb:YMR272C(locus name)|uniprotkb:YM8156.14C(orf name)|uniprotkb:Suppressor of calcium sensitivity 7(gene name synonym)|uniprotkb:4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Dihydroceramide fatty acyl 2-hydroxylase SCS7(gene name synonym)|uniprotkb:Sphingolipid alpha-hydroxylase(gene name synonym) psi-mi:tgl5_yeast(display_long)|uniprotkb:TGL5(gene name)|psi-mi:TGL5(display_short)|uniprotkb:STC2(gene name synonym)|uniprotkb:YOR29-32(orf name)|uniprotkb:YOR2964C(orf name)|uniprotkb:YOR081C(locus name)|uniprotkb:Lipase 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341321|imex:IM-14275-2490 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR272C(gene)|ensemblfungi:YMR272C_mRNA(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0080132"(fatty acid alpha-hydroxylase activity)|go:"GO:0102771"(sphingolipid very long chain fatty acid alpha-hydroxylase activity)|rcsb pdb:4ZR0|rcsb pdb:4ZR1|reactome:R-SCE-1660661|refseq:NP_013999.1|sgd:S000004885|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR006694(Fatty acid hydroxylase)|interpro:IPR014430(Inositolphosphorylceramide-B hydroxylase)|mint:Q03529|interpro:IPR036400 refseq:NP_014724.1|sgd:S000005607|mint:Q12043|dip:DIP-6280N|ensemblfungi:YOR081C(gene)|ensemblfungi:YOR081C_mRNA(transcript)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042171"(lysophosphatidic acid acyltransferase activity)|interpro:IPR002641(Patatin)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR021771 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:M34W8LH4q+H1EOi7khg+f/TKtgQ559292 rogid:ccHxygbWfyyQXKaSbOL4iYhikms559292 intact-crc:9E37FBDEA45437C2|rigid:roZDGYEUT1DVUv7mjdueE9aNWvs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:Q03554 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-2057821|uniprotkb:D6W0B9|ensemblfungi:YMR292W psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:got1_yeast(display_long)|uniprotkb:GOT1(gene name)|psi-mi:GOT1(display_short)|uniprotkb:Golgi transport protein 1(gene name synonym)|uniprotkb:YMR292W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341332|imex:IM-14275-2491 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 refseq:NP_014020.1|sgd:S000004906|dip:DIP-8271N|mint:Q03554|ensemblfungi:YMR292W(gene)|ensemblfungi:YMR292W_mRNA(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein) psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:wO79x4uMwWaL6v00y28srGL561E559292 intact-crc:D60A3EA5E542265C|rigid:WQRO7AAZZDoS03p2MV2zWtRtsF0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03554 uniprotkb:P25361 intact:EBI-2057821|uniprotkb:D6W0B9|ensemblfungi:YMR292W intact:EBI-21909|uniprotkb:D6VR52|ensemblfungi:YCR043C psi-mi:got1_yeast(display_long)|uniprotkb:GOT1(gene name)|psi-mi:GOT1(display_short)|uniprotkb:Golgi transport protein 1(gene name synonym)|uniprotkb:YMR292W(locus name) psi-mi:yct3_yeast(display_long)|uniprotkb:YCR43C(orf name)|uniprotkb:YCR725(orf name)|uniprotkb:YCR043C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341343|imex:IM-14275-2492 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014020.1|sgd:S000004906|dip:DIP-8271N|mint:Q03554|ensemblfungi:YMR292W(gene)|ensemblfungi:YMR292W_mRNA(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein) sgd:S000000639|refseq:NP_009972.1|mint:P25361|ensemblfungi:YCR043C(gene)|ensemblfungi:YCR043C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0043332"(mating projection tip) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wO79x4uMwWaL6v00y28srGL561E559292 rogid:bEMtsAa5vCsWqGOiXwBK40Pa0xQ559292 intact-crc:6A67230F709E4378|rigid:uR+FN7G2IGg/n7vn1lBl/D6+qME false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38166 uniprotkb:Q03554 intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W intact:EBI-2057821|uniprotkb:D6W0B9|ensemblfungi:YMR292W psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short) psi-mi:got1_yeast(display_long)|uniprotkb:GOT1(gene name)|psi-mi:GOT1(display_short)|uniprotkb:Golgi transport protein 1(gene name synonym)|uniprotkb:YMR292W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341354|imex:IM-14275-2493 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166 refseq:NP_014020.1|sgd:S000004906|dip:DIP-8271N|mint:Q03554|ensemblfungi:YMR292W(gene)|ensemblfungi:YMR292W_mRNA(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein) psi-mi:"MI:0469"(intact) crc64:1BF971749814382C - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292 rogid:wO79x4uMwWaL6v00y28srGL561E559292 intact-crc:CAF6361223FBC3E2|rigid:bQODb3sOA5X6cd0DKtQMOg8J/aw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:Q03554 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-2057821|uniprotkb:D6W0B9|ensemblfungi:YMR292W psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:got1_yeast(display_long)|uniprotkb:GOT1(gene name)|psi-mi:GOT1(display_short)|uniprotkb:Golgi transport protein 1(gene name synonym)|uniprotkb:YMR292W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341365|imex:IM-14275-2494 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N refseq:NP_014020.1|sgd:S000004906|dip:DIP-8271N|mint:Q03554|ensemblfungi:YMR292W(gene)|ensemblfungi:YMR292W_mRNA(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:wO79x4uMwWaL6v00y28srGL561E559292 intact-crc:2BC797CB590534EC|rigid:HCLgHmAXGIKiVh/eksgKE/cOqJU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38353 uniprotkb:Q03554 intact:EBI-18175|uniprotkb:D6VQS8|ensemblfungi:YBR283C intact:EBI-2057821|uniprotkb:D6W0B9|ensemblfungi:YMR292W psi-mi:ssh1_yeast(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:Ssh1 complex subunit alpha(gene name synonym)|uniprotkb:Ssh1 complex subunit SSH1(gene name synonym)|uniprotkb:YBR2020(orf name)|uniprotkb:YBR283C(locus name) psi-mi:got1_yeast(display_long)|uniprotkb:GOT1(gene name)|psi-mi:GOT1(display_short)|uniprotkb:Golgi transport protein 1(gene name synonym)|uniprotkb:YMR292W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341376|imex:IM-14275-2495 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009842.1|sgd:S000000487|ensemblfungi:YBR283C(gene)|ensemblfungi:YBR283C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:2WW9|rcsb pdb:2WWA|dip:DIP-4962N|mint:P38353 refseq:NP_014020.1|sgd:S000004906|dip:DIP-8271N|mint:Q03554|ensemblfungi:YMR292W(gene)|ensemblfungi:YMR292W_mRNA(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein) psi-mi:"MI:0469"(intact) crc64:48267EEA3E0191BD - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:76wvZIdv7W5BQn6wI+sHOGQAyuc559292 rogid:wO79x4uMwWaL6v00y28srGL561E559292 intact-crc:538BF6D466AACAF3|rigid:asKbB6N4kkbExgAPxj2iekNaxTY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38694 uniprotkb:Q03554 intact:EBI-24511|uniprotkb:D3DKY6|ensemblfungi:YHR039C intact:EBI-2057821|uniprotkb:D6W0B9|ensemblfungi:YMR292W psi-mi:msc7_yeast(display_long)|uniprotkb:MSC7(gene name)|psi-mi:MSC7(display_short)|uniprotkb:Meiotic sister-chromatid recombination protein 7(gene name synonym)|uniprotkb:YHR039C(locus name) psi-mi:got1_yeast(display_long)|uniprotkb:GOT1(gene name)|psi-mi:GOT1(display_short)|uniprotkb:Golgi transport protein 1(gene name synonym)|uniprotkb:YMR292W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341387|imex:IM-14275-2496 author score:99.34 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011904.1|sgd:S000001081|dip:DIP-1878N|mint:P38694|ensemblfungi:YHR039C(gene)|ensemblfungi:YHR039C_mRNA(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007131"(reciprocal meiotic recombination)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510 refseq:NP_014020.1|sgd:S000004906|dip:DIP-8271N|mint:Q03554|ensemblfungi:YMR292W(gene)|ensemblfungi:YMR292W_mRNA(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.34|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p2xtb6/xYI/jfPNtO6JRZs+5t6I559292 rogid:wO79x4uMwWaL6v00y28srGL561E559292 intact-crc:D753D3CB63CE6101|rigid:QJs3m/qVq22IKhTsP9AFniOzlH0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03554 uniprotkb:P39010 intact:EBI-2057821|uniprotkb:D6W0B9|ensemblfungi:YMR292W intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C psi-mi:got1_yeast(display_long)|uniprotkb:GOT1(gene name)|psi-mi:GOT1(display_short)|uniprotkb:Golgi transport protein 1(gene name synonym)|uniprotkb:YMR292W(locus name) psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341398|imex:IM-14275-2497 author score:99.34 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014020.1|sgd:S000004906|dip:DIP-8271N|mint:Q03554|ensemblfungi:YMR292W(gene)|ensemblfungi:YMR292W_mRNA(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein) refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.34|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wO79x4uMwWaL6v00y28srGL561E559292 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 intact-crc:F3C67AB8B3D84763|rigid:/YrtBMHubTpN/Q59PPvZwqDvAJ8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03554 uniprotkb:P53337 intact:EBI-2057821|uniprotkb:D6W0B9|ensemblfungi:YMR292W intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C psi-mi:got1_yeast(display_long)|uniprotkb:GOT1(gene name)|psi-mi:GOT1(display_short)|uniprotkb:Golgi transport protein 1(gene name synonym)|uniprotkb:YMR292W(locus name) psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341409|imex:IM-14275-2498 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014020.1|sgd:S000004906|dip:DIP-8271N|mint:Q03554|ensemblfungi:YMR292W(gene)|ensemblfungi:YMR292W_mRNA(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein) refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wO79x4uMwWaL6v00y28srGL561E559292 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 intact-crc:3CB5BA0ECEC3969D|rigid:nZ+osClQwyakymlXXDbzH4qZslk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03554 uniprotkb:P54837 intact:EBI-2057821|uniprotkb:D6W0B9|ensemblfungi:YMR292W intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:got1_yeast(display_long)|uniprotkb:GOT1(gene name)|psi-mi:GOT1(display_short)|uniprotkb:Golgi transport protein 1(gene name synonym)|uniprotkb:YMR292W(locus name) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341420|imex:IM-14275-2499 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014020.1|sgd:S000004906|dip:DIP-8271N|mint:Q03554|ensemblfungi:YMR292W(gene)|ensemblfungi:YMR292W_mRNA(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wO79x4uMwWaL6v00y28srGL561E559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:39079FF9CEEBA5E9|rigid:GNbEIyqmrrZ8ab583VnLo/BxCeQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:Q03554 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-2057821|uniprotkb:D6W0B9|ensemblfungi:YMR292W psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:got1_yeast(display_long)|uniprotkb:GOT1(gene name)|psi-mi:GOT1(display_short)|uniprotkb:Golgi transport protein 1(gene name synonym)|uniprotkb:YMR292W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341431|imex:IM-14275-2500 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_014020.1|sgd:S000004906|dip:DIP-8271N|mint:Q03554|ensemblfungi:YMR292W(gene)|ensemblfungi:YMR292W_mRNA(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:wO79x4uMwWaL6v00y28srGL561E559292 intact-crc:32D5E64F37B84DC2|rigid:+4HYnsU4BDNLa4u8li3awxnqbqU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:Q03554 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-2057821|uniprotkb:D6W0B9|ensemblfungi:YMR292W psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:got1_yeast(display_long)|uniprotkb:GOT1(gene name)|psi-mi:GOT1(display_short)|uniprotkb:Golgi transport protein 1(gene name synonym)|uniprotkb:YMR292W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341442|imex:IM-14275-2501 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 refseq:NP_014020.1|sgd:S000004906|dip:DIP-8271N|mint:Q03554|ensemblfungi:YMR292W(gene)|ensemblfungi:YMR292W_mRNA(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:wO79x4uMwWaL6v00y28srGL561E559292 intact-crc:529992E80A0BD5A6|rigid:92dkGBdeUcpXrc/9j4tZZU/2C2U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03554 uniprotkb:Q99287 intact:EBI-2057821|uniprotkb:D6W0B9|ensemblfungi:YMR292W intact:EBI-37523|uniprotkb:D6W2M3|ensemblfungi:YOR165W psi-mi:got1_yeast(display_long)|uniprotkb:GOT1(gene name)|psi-mi:GOT1(display_short)|uniprotkb:Golgi transport protein 1(gene name synonym)|uniprotkb:YMR292W(locus name) psi-mi:sey1_yeast(display_long)|uniprotkb:SEY1(gene name)|psi-mi:SEY1(display_short)|uniprotkb:YOR165W(locus name)|uniprotkb:Synthetic enhancer of YOP1 protein(gene name synonym)|uniprotkb:O3590(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341453|imex:IM-14275-2502 author score:99.34 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014020.1|sgd:S000004906|dip:DIP-8271N|mint:Q03554|ensemblfungi:YMR292W(gene)|ensemblfungi:YMR292W_mRNA(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein) refseq:NP_014808.1|sgd:S000005691|dip:DIP-49373N|mint:Q99287|ensemblfungi:YOR165W(gene)|ensemblfungi:YOR165W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0061024"(membrane organization)|go:"GO:0071944"(cell periphery)|interpro:IPR008803(Root hair defective 3 GTP-binding)|interpro:IPR027417|interpro:IPR030386 psi-mi:"MI:0469"(intact) - crc64:DEC0C9EC3AB172DF figure legend:tables S3 and S4|author-confidence:99.34|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wO79x4uMwWaL6v00y28srGL561E559292 rogid:zFsgalfyUvAuuV51vChJjraiQmI559292 intact-crc:22950535CE9C2311|rigid:2o691xQ7BlpKcpWFoZC2ZD6aSmc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40016 uniprotkb:Q03557 intact:EBI-15927|uniprotkb:D3DLS0|ensemblfungi:YER021W intact:EBI-7372|uniprotkb:D6W0C0|ensemblfungi:YMR293C psi-mi:rpn3_yeast(display_long)|uniprotkb:RPN3(gene name)|psi-mi:RPN3(display_short)|uniprotkb:SUN2(gene name synonym)|uniprotkb:YER021W(locus name) psi-mi:gata_yeast(display_long)|uniprotkb:LRC6(gene name synonym)|uniprotkb:YMR293C(locus name)|uniprotkb:HER2(gene name)|psi-mi:HER2(display_short)|uniprotkb:Loss of respiratory capacity protein 6(gene name synonym)|uniprotkb:GEP6(gene name synonym)|uniprotkb:HMG2-induced ER-remodeling protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341464|imex:IM-14275-2503 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010938.1|sgd:S000000823|ensemblfungi:YER021W(gene)|ensemblfungi:YER021W_mRNA(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042176"(regulation of protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|dip:DIP-1322N|mint:P40016 refseq:NP_014021.1|sgd:S000004907|mint:Q03557|dip:DIP-2695N|ensemblfungi:YMR293C(gene)|ensemblfungi:YMR293C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030956"("glutamyl-tRNA(Gln) amidotransferase complex")|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0070681"(glutaminyl-tRNAGln biosynthesis via transamidation)|interpro:IPR000120(Amidase signature enzyme)|interpro:IPR004412("Glutamyl-tRNA(Gln) amidotransferase A subunit")|interpro:IPR020556|interpro:IPR023631|interpro:IPR036928|rcsb pdb:4N0H|rcsb pdb:4N0I psi-mi:"MI:0469"(intact) crc64:B08B58663DDA85DC - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pXkyoZKr0rI5usi19R+TvS4hSso559292 rogid:mm2uYip0Dm9baIOB2J6NSuPSlmI559292 intact-crc:393E4A9C75D1D55B|rigid:RBpTdZLJL/TXKqL4SXdBY2sPB6Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03557 uniprotkb:Q12247 intact:EBI-7372|uniprotkb:D6W0C0|ensemblfungi:YMR293C intact:EBI-36471|uniprotkb:D6VY69|ensemblfungi:YLR068W psi-mi:gata_yeast(display_long)|uniprotkb:LRC6(gene name synonym)|uniprotkb:YMR293C(locus name)|uniprotkb:HER2(gene name)|psi-mi:HER2(display_short)|uniprotkb:Loss of respiratory capacity protein 6(gene name synonym)|uniprotkb:GEP6(gene name synonym)|uniprotkb:HMG2-induced ER-remodeling protein 2(gene name synonym) psi-mi:fyv7_yeast(display_long)|uniprotkb:FYV7(gene name)|psi-mi:FYV7(display_short)|uniprotkb:L2192(orf name)|uniprotkb:Function required for yeast viability protein 7(gene name synonym)|uniprotkb:YLR068W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341475|imex:IM-14275-2504 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014021.1|sgd:S000004907|mint:Q03557|dip:DIP-2695N|ensemblfungi:YMR293C(gene)|ensemblfungi:YMR293C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030956"("glutamyl-tRNA(Gln) amidotransferase complex")|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0070681"(glutaminyl-tRNAGln biosynthesis via transamidation)|interpro:IPR000120(Amidase signature enzyme)|interpro:IPR004412("Glutamyl-tRNA(Gln) amidotransferase A subunit")|interpro:IPR020556|interpro:IPR023631|interpro:IPR036928|rcsb pdb:4N0H|rcsb pdb:4N0I refseq:NP_013169.1|sgd:S000004058|mint:Q12247|dip:DIP-4827N|ensemblfungi:YLR068W(gene)|ensemblfungi:YLR068W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|interpro:IPR013730(rRNA processing)|interpro:IPR017265(rRNA processing, FYV7) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mm2uYip0Dm9baIOB2J6NSuPSlmI559292 rogid:dhsTeopeJ2J1YkT5kRgGvxbFJhw559292 intact-crc:7C566ADA5E22FA2C|rigid:gfa+s03paEmYE2hDvGT2ezRQgx0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:P19807 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341486|imex:IM-14275-2505 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:3DE938F1EBB2FFE1|rigid:I3sG1iLV7rVFq3ayac2xkGf5gIE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:P23585 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-2054100|uniprotkb:D6VZI5|ensemblfungi:YMR011W psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:hxt2_yeast(display_long)|uniprotkb:YM8270.15(orf name)|uniprotkb:YMR011W(locus name)|uniprotkb:HXT2(gene name)|psi-mi:HXT2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341497|imex:IM-14275-2506 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 refseq:NP_013724.1|sgd:S000004613|dip:DIP-7912N|mint:P23585|ensemblfungi:YMR011W(gene)|ensemblfungi:YMR011W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:d4PFyh6BHnB/WnnF3A4GF3EphgY559292 intact-crc:9204730317998C68|rigid:j4GxmfjAknySjJQoU/scNXF9434 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:P25619 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341508|imex:IM-14275-2507 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:1556801228E8462F|rigid:/7XMkRRblEQUWpV3W6RAXn0y1QU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:P32465 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341519|imex:IM-14275-2508 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 intact-crc:26E6038D48F9EC3B|rigid:1jsXXDAd5ZmCTaJfGJQT4TOPS5g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32568 uniprotkb:Q03640 intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341530|imex:IM-14275-2509 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) - crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:E50962BEEBAE6A18|rigid:1U2/WvhGanTUirTXqn2beKkyioE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:P33413 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-2060312|uniprotkb:D3DKP5|ensemblfungi:YHL016C psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:dur3_yeast(display_long)|uniprotkb:DUR3(gene name)|psi-mi:DUR3(display_short)|uniprotkb:YHL016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341541|imex:IM-14275-2510 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 interpro:IPR031155|refseq:NP_011847.1|sgd:S000001008|interpro:IPR001734(Na+/solute symporter)|interpro:IPR038377|mint:P33413|ensemblfungi:YHL016C(gene)|ensemblfungi:YHL016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0015204"(urea transmembrane transporter activity)|go:"GO:0015489"(putrescine transmembrane transporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015840"(urea transport)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:oTFsdtOngA3q5wCbhK/fpVlIsz0559292 intact-crc:D13FECF7D8DED5C3|rigid:AIZihqzE0KMy9j/ink06CPn/x5s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:P35735 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341552|imex:IM-14275-2511 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:F6CA2CAA5EBCAB7A|rigid:q5S/W8pA+xZENNHNgHStMRq1pGI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:P36027 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341563|imex:IM-14275-2512 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:F5243A0020EDDDCD|rigid:/uVlZg0gYAkUyJN8hCfgPxMZ99k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:P38234 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341574|imex:IM-14275-2513 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 intact-crc:176AE043E3D34804|rigid:xVMmTeDP6JifWMI+QWMyEfmC6dI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38695 uniprotkb:Q03640 intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341585|imex:IM-14275-2514 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) crc64:6906721BAC1A5F87 crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:881D644772291A52|rigid:mtGY21Rlb7jv1M08+skaSom8ojg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40260 uniprotkb:Q03640 intact:EBI-10714|ensemblfungi:YGR121C|uniprotkb:D6VUQ2 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:mep1_yeast(display_long)|uniprotkb:MEP1(gene name)|psi-mi:MEP1(display_short)|uniprotkb:YGR121C(locus name)|uniprotkb:G6331(orf name)|uniprotkb:AMT1(gene name synonym) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341596|imex:IM-14275-2515 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR121C(gene)|ensemblfungi:YGR121C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|sgd:S000003353|refseq:NP_011636.3|mint:P40260|dip:DIP-5530N refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) - crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VnoBl5jhQD24N0SbCLv68HCwl1U559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:E04963D5277D9301|rigid:gMZJwzg0tDEFeR3pq9FrnjQyswY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:Q03640 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341607|imex:IM-14275-2516 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) - crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:76959D21CDD5BB11|rigid:CrMcaWTXBMndAb2UXsp2JdZ8enc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53049 uniprotkb:Q03640 intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341618|imex:IM-14275-2517 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) - crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:33EC1C6819BB4D53|rigid:/1R0ku9Niv3QRNBQugceTDV20ig false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:P53283 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341629|imex:IM-14275-2518 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 intact-crc:02B9AC94BF93EF97|rigid:632/xu49x0U8MagNYh6uo6o97+s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53388 uniprotkb:Q03640 intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341640|imex:IM-14275-2519 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) crc64:488A382656039D0B crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:C75B4EDC93D13838|rigid:BxESnw+N2QxFaPKtpv42xP3dH5E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:P53390 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341651|imex:IM-14275-2520 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 crc64:2309338F36D96258 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 intact-crc:A0367F497CA083B0|rigid:/D0ltj1q+0UX6AKoBZXFnqVM1uU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:P53832 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-2055941|uniprotkb:D6W0R1|ensemblfungi:YNL283C psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:wsc2_yeast(display_long)|uniprotkb:YNL283C(locus name)|uniprotkb:N0583(orf name)|uniprotkb:WSC2(gene name)|psi-mi:WSC2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341662|imex:IM-14275-2521 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 refseq:NP_014116.1|sgd:S000005227|interpro:IPR002889(Carbohydrate-binding WSC)|mint:P53832|ensemblfungi:YNL283C(gene)|ensemblfungi:YNL283C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip) psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 - figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:5wadvTv6SxcIAb60yfnuGMfa8pY559292 intact-crc:33BB55F02AEAA080|rigid:C2btiMTKPRSNA5pCkMQ5OUTVYQw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02785 uniprotkb:Q03640 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341673|imex:IM-14275-2522 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) - crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:BB601E423AF1F22F|rigid:QG9uHGSKg+ZI6MSZpQn/L4VA7/U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:Q03516 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-27593|ensemblfungi:YMR266W|uniprotkb:D6W092 psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:rsn1_yeast(display_long)|uniprotkb:YMR266W(locus name)|uniprotkb:YM8156.08(orf name)|uniprotkb:RSN1(gene name)|psi-mi:RSN1(display_short)|uniprotkb:Rescuer of SRO7 at high Nacl protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341684|imex:IM-14275-2523 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 ensemblfungi:YMR266W(gene)|ensemblfungi:YMR266W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR003864(Protein of unknown function DUF221)|interpro:IPR022257|interpro:IPR027815|interpro:IPR032880|refseq:NP_013993.1|sgd:S000004879|dip:DIP-6549N|mint:Q03516 psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 crc64:F6F7BA2B3F3AD44B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:oyJcJS+pUv9eWbLk5ImUT6Cfa1A559292 intact-crc:AC29332EDC2491FD|rigid:YG2o2JIHxC8gj43UADMAiIqehbc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:Q03640 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341695|imex:IM-14275-2524 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:AA3C6A0D5B19AC8C|rigid:hZU8GNtrZDOVJiT5oPes2T0X7mA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06170 uniprotkb:Q03640 intact:EBI-35994|uniprotkb:D6VYW8|ensemblfungi:YLR326W intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:yl326_yeast(display_long)|uniprotkb:YLR326W(locus name) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341706|imex:IM-14275-2525 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013430.1|sgd:S000004318|mint:Q06170|dip:DIP-3995N|ensemblfungi:YLR326W(gene)|ensemblfungi:YLR326W_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR025187 refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) crc64:724CD7833AA9B416 crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ufkoj1kRp4Y9JTsgbL+3k8hzJyo559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:C4282B1E5DA2F711|rigid:6Icx1AXXDzwSDzhMZ0XzCVWnUi4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06451 uniprotkb:Q03640 intact:EBI-34275|uniprotkb:D6W4F2|ensemblfungi:YPR156C intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:tpo3_yeast(display_long)|uniprotkb:TPO3(gene name)|psi-mi:TPO3(display_short)|uniprotkb:P9584.7(orf name)|uniprotkb:YPR156C(locus name) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341717|imex:IM-14275-2526 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015482.1|sgd:S000006360|mint:Q06451|dip:DIP-3907N|ensemblfungi:YPR156C(gene)|ensemblfungi:YPR156C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) crc64:D260ED161F800502 crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oVpx7Bjk/mK2Q7+/j05tX3gHw7k559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:8B3A737313A3F3DC|rigid:/N/N4c1SuwjMruDCMDFVFDxGiQA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06689 uniprotkb:Q03640 intact:EBI-38659|uniprotkb:D6VZ50|ensemblfungi:YLR413W intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:yl413_yeast(display_long)|uniprotkb:YLR413W(locus name) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341728|imex:IM-14275-2527 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013517.1|sgd:S000004405|mint:Q06689|dip:DIP-5075N|ensemblfungi:YLR413W(gene)|ensemblfungi:YLR413W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0071944"(cell periphery)|interpro:IPR009571(SUR7) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) crc64:92E23436DC857E95 crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AoTGKjLhw0NECrtuftZqLANonds559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:768C004EA5D0CD46|rigid:hiaKon5TdtgR8mRBLL3nbNUW9Zk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:Q07824 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341739|imex:IM-14275-2528 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 intact-crc:1489A98F9FDD8716|rigid:umWYWx33vPY+PiWl7wfoMlItsWo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08967 uniprotkb:Q03640 intact:EBI-36673|uniprotkb:D6W3E9|ensemblfungi:YPL221W intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:flc1_yeast(display_long)|uniprotkb:FAD transporter 1(gene name synonym)|uniprotkb:FLC1(gene name)|psi-mi:FLC1(display_short)|uniprotkb:TRP-like ion channel protein FLC1(gene name synonym)|uniprotkb:Heme utilization factor 1(gene name synonym)|uniprotkb:Bypass of PAM1 protein 1(gene name synonym)|uniprotkb:HUF1(gene name synonym)|uniprotkb:YPL221W(locus name)|uniprotkb:BOP1(gene name synonym) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341750|imex:IM-14275-2529 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015103.1|sgd:S000006142|mint:Q08967|dip:DIP-3965N|ensemblfungi:YPL221W(gene)|ensemblfungi:YPL221W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055085"(transmembrane transport)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241 refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) - crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:r6CcZGEjxHUk2w0iBUBvnAPaFd4559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:5DAB3313851852B0|rigid:rhXPX9tnBlZ6Sg/5o/GEdnxeVTY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12256 uniprotkb:Q03640 intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341761|imex:IM-14275-2530 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) - crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:19E079386B2F27FA|rigid:vq47VD8t486RE7poWKiPBCJcktk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3E756 uniprotkb:Q03640 intact:EBI-2044812|uniprotkb:D6VPX0|ensemblfungi:YBL029C-A intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:yb029_yeast(display_long)|uniprotkb:YBL029C-A(locus name) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341772|imex:IM-14275-2531 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000007591|refseq:NP_076874.1|mint:Q3E756|ensemblfungi:YBL029C-A(gene)|ensemblfungi:YBL029C-A_mRNA(transcript)|go:"GO:0005886"(plasma membrane) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) - crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Y9LDkESr65DK5SLFNTw1dBKeqPc559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:8236D24C0EA99A48|rigid:oYb6Cr5DZio7gnj+72xNp8ykKok false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:Q03653 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-27465|uniprotkb:D6W037|ensemblfungi:YMR212C psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:efr3_yeast(display_long)|uniprotkb:YM8261.06C(orf name)|uniprotkb:YMR212C(locus name)|uniprotkb:EFR3(gene name)|psi-mi:EFR3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341783|imex:IM-14275-2532 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N mint:Q03653|ensemblfungi:YMR212C(gene)|ensemblfungi:YMR212C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|refseq:NP_013939.1|sgd:S000004825|dip:DIP-5686N|interpro:IPR039786|rcsb pdb:4N5A psi-mi:"MI:0469"(intact) crc64:8B7F009521F72C15 - figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:7idWvmQ422iUpDKDXH4z05LW1tg559292 intact-crc:9BB6B6F12DE6D5C2|rigid:B3h2fXpHnqzy7mQ1LMqNCdRrebM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03653 uniprotkb:P36027 intact:EBI-27465|uniprotkb:D6W037|ensemblfungi:YMR212C intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:efr3_yeast(display_long)|uniprotkb:YM8261.06C(orf name)|uniprotkb:YMR212C(locus name)|uniprotkb:EFR3(gene name)|psi-mi:EFR3(display_short) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341794|imex:IM-14275-2533 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q03653|ensemblfungi:YMR212C(gene)|ensemblfungi:YMR212C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|refseq:NP_013939.1|sgd:S000004825|dip:DIP-5686N|interpro:IPR039786|rcsb pdb:4N5A ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:7idWvmQ422iUpDKDXH4z05LW1tg559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:94B09CB168D4CB6E|rigid:sBNVNfN6yx4OeHnjK4J2MDWFB54 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46951 uniprotkb:Q03653 intact:EBI-23455|uniprotkb:D6VUY0|ensemblfungi:YGR198W intact:EBI-27465|uniprotkb:D6W037|ensemblfungi:YMR212C psi-mi:ypp1_yeast(display_long)|uniprotkb:YGR198W(locus name)|uniprotkb:G7594(orf name)|uniprotkb:YPP1(gene name)|psi-mi:YPP1(display_short)|uniprotkb:Alpha-synuclein protective protein 1(gene name synonym) psi-mi:efr3_yeast(display_long)|uniprotkb:YM8261.06C(orf name)|uniprotkb:YMR212C(locus name)|uniprotkb:EFR3(gene name)|psi-mi:EFR3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341805|imex:IM-14275-2534 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003430|refseq:NP_011714.3|dip:DIP-6350N|mint:P46951|ensemblfungi:YGR198W(gene)|ensemblfungi:YGR198W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0019236"(response to pheromone)|go:"GO:0030479"(actin cortical patch)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:4N5C|go:"GO:0005829"(cytosol) mint:Q03653|ensemblfungi:YMR212C(gene)|ensemblfungi:YMR212C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|refseq:NP_013939.1|sgd:S000004825|dip:DIP-5686N|interpro:IPR039786|rcsb pdb:4N5A psi-mi:"MI:0469"(intact) crc64:AC42730C8B9C3E4B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:DN/jdwQiPEurX88Vs2Lj5oXMLzQ559292 rogid:7idWvmQ422iUpDKDXH4z05LW1tg559292 intact-crc:79320FF6DFD2A081|rigid:j8MM1dOd5/gGW3UeEgjxkKTMKLI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03687 uniprotkb:P09620 intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341816|imex:IM-14275-2535 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:FB229586E1EF49E7|rigid:6xKme0rsdctmusedKjQ1Y4YQSCI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03687 uniprotkb:P11076 intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341827|imex:IM-14275-2536 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 psi-mi:"MI:0469"(intact) - crc64:796859026AC63CC0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 intact-crc:A9EE567A19A92D68|rigid:ch0MrGc8urJIzcfP7kG0AGeOTrU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:Q03687 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341838|imex:IM-14275-2537 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 intact-crc:1C452576BBC717C4|rigid:V7iomxJBKS8U9UJhsWt5QSSiGlE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03687 uniprotkb:P25361 intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W intact:EBI-21909|uniprotkb:D6VR52|ensemblfungi:YCR043C psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:yct3_yeast(display_long)|uniprotkb:YCR43C(orf name)|uniprotkb:YCR725(orf name)|uniprotkb:YCR043C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341849|imex:IM-14275-2538 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) sgd:S000000639|refseq:NP_009972.1|mint:P25361|ensemblfungi:YCR043C(gene)|ensemblfungi:YCR043C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0043332"(mating projection tip) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 rogid:bEMtsAa5vCsWqGOiXwBK40Pa0xQ559292 intact-crc:15834BD08C75484C|rigid:KG/mw1rNr1XW0sX0gwH5wro+nGk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30605 uniprotkb:Q03687 intact:EBI-2050956|uniprotkb:D6VTB9|ensemblfungi:YDR497C intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W psi-mi:itr1_yeast(display_long)|uniprotkb:D9719.3(orf name)|uniprotkb:YDR497C(locus name)|uniprotkb:ITR1(gene name)|psi-mi:ITR1(display_short) psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341860|imex:IM-14275-2539 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010785.1|sgd:S000002905|dip:DIP-7406N|mint:P30605|ensemblfungi:YDR497C(gene)|ensemblfungi:YDR497C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GgtK4YFe7ZCZcmVpV5q1KY2F0Ds559292 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 intact-crc:6229C5B80B2A62C6|rigid:pXBuHRVz2KpvteyKfYHVnmQPuKE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03687 uniprotkb:P32074 intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W intact:EBI-4891|ensemblfungi:YNL287W|uniprotkb:D6W0Q6 psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:copg_yeast(display_long)|uniprotkb:SEC21(gene name)|psi-mi:SEC21(display_short)|uniprotkb:YNL287W(locus name)|uniprotkb:N0543(orf name)|uniprotkb:Gamma-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341871|imex:IM-14275-2540 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|ensemblfungi:YNL287W(gene)|ensemblfungi:YNL287W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|refseq:NP_014112.1|sgd:S000005231|dip:DIP-1611N|mint:P32074|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - crc64:99DC7D737D4EF761 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 rogid:uAs2hcx4DNS58qP1YDaUKgqZQm0559292 intact-crc:32969A0EA15A1022|rigid:8tb8yi0RCkO5XHxtnfPw14cTPGQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03687 uniprotkb:P32319 intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W intact:EBI-13123|uniprotkb:D6VPY3|ensemblfungi:YBL017C psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:vps10_yeast(display_long)|uniprotkb:PEP1(gene name)|psi-mi:PEP1(display_short)|uniprotkb:Vacuolar carboxypeptidase sorting receptor VPS10(gene name synonym)|uniprotkb:Carboxypeptidase Y receptor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 1(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 1(gene name synonym)|uniprotkb:Sortilin VPS10(gene name synonym)|uniprotkb:VPS10(gene name synonym)|uniprotkb:VPT1(gene name synonym)|uniprotkb:YBL03.22(orf name)|uniprotkb:YBL0302(orf name)|uniprotkb:YBL017C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341882|imex:IM-14275-2541 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) refseq:NP_009536.1|sgd:S000000113|mint:P32319|dip:DIP-5900N|ensemblfungi:YBL017C(gene)|ensemblfungi:YBL017C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000423"(mitophagy)|go:"GO:0000425"(pexophagy)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048203"(vesicle targeting, trans-Golgi to endosome)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR036278 psi-mi:"MI:0469"(intact) - crc64:C778A0400612ECF4 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 rogid:dYYsekAaDw4SzmEUSe5tYb5a43M559292 intact-crc:0FE1393D198BF9A3|rigid:RhtGJuGOYp5JIcdmgWNOhOuo5BY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03687 uniprotkb:P39010 intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341893|imex:IM-14275-2542 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 intact-crc:8C24D2674F334C57|rigid:2wQJgMJ0EtOujfLg6RNYPm6e5/A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40094 uniprotkb:Q03687 intact:EBI-16605|ensemblfungi:YER157W|uniprotkb:D3DM64 intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W psi-mi:cog3_yeast(display_long)|uniprotkb:COG3(gene name)|psi-mi:COG3(display_short)|uniprotkb:GRD20(gene name synonym)|uniprotkb:SEC34(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 3(gene name synonym)|uniprotkb:Protein SEC34(gene name synonym)|uniprotkb:YER157W(locus name) psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341904|imex:IM-14275-2543 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER157W(gene)|ensemblfungi:YER157W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR007265(Sec34-like protein)|refseq:NP_011084.1|sgd:S000000959|dip:DIP-4728N|mint:P40094 refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) psi-mi:"MI:0469"(intact) crc64:C7AFBE99010FE571 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R2r0ZW+nxrykdTHq1cJy9zOmvHo559292 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 intact-crc:4F14BC40B83EC0D4|rigid:vwlzyX5gKk8oj0aYshu54/QjsAI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03687 uniprotkb:P40335 intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W intact:EBI-20373|uniprotkb:D6VWC9|intact:EBI-3674163|uniprotkb:E9P910|ensemblfungi:YJL053W psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:pep8_yeast(display_long)|uniprotkb:PEP8(gene name)|psi-mi:PEP8(display_short)|uniprotkb:GRD6(gene name synonym)|uniprotkb:VPS26(gene name synonym)|uniprotkb:VPT4(gene name synonym)|uniprotkb:J1152(orf name)|uniprotkb:YJL053W(locus name)|uniprotkb:Vacuolar protein-targeting protein 4(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 26(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341915|imex:IM-14275-2544 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) refseq:NP_012482.1|sgd:S000003589|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0140318"(protein transporter activity)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR028934|reactome:R-SCE-3238698|ensemblfungi:YJL053W(gene)|ensemblfungi:YJL053W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|dip:DIP-4572N|mint:P40335 psi-mi:"MI:0469"(intact) - crc64:40D15594E70A9B58 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 rogid:mwZb20cO8nZl8hVUSRXAB5Varg0559292 intact-crc:68EF1F4429DBA0EE|rigid:3RtlrArwXJSmnBlHpmg2RqyTqKk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41811 uniprotkb:Q03687 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341926|imex:IM-14275-2545 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) psi-mi:"MI:0469"(intact) crc64:6A5E50BBEB02CB58 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 intact-crc:AB995B37D56F1A2D|rigid:SyX3n+feZ+QkyPWY36yGNgJpOO8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43621 uniprotkb:Q03687 intact:EBI-4876|uniprotkb:D6VTT4|ensemblfungi:YFR051C intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W psi-mi:copd_yeast(display_long)|uniprotkb:RET2(gene name)|psi-mi:RET2(display_short)|uniprotkb:YFR051C(locus name)|uniprotkb:Delta-coat protein(gene name synonym) psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341937|imex:IM-14275-2546 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001947|refseq:NP_116709.3|dip:DIP-5255N|mint:P43621|ensemblfungi:YFR051C(gene)|ensemblfungi:YFR051C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|rcsb pdb:5FJW|rcsb pdb:5FJX|rcsb pdb:5FJZ|rcsb pdb:5FK0|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) psi-mi:"MI:0469"(intact) crc64:AA730F046655EE5A - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:auvjuT8ffm1R4P3mRKEIWAsynW0559292 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 intact-crc:40DFCBF5D896FD26|rigid:eQVsDwyEvuWpI7j9iW1c7Rf3yeU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03687 uniprotkb:P50276 intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341948|imex:IM-14275-2547 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:573982769DA05334|rigid:cls0x+LU5QxWOPKpeQKfg4DzCBg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53728 uniprotkb:Q03687 intact:EBI-5444|uniprotkb:E9P900|uniprotkb:D6W1K2|ensemblfungi:YNR028W intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W psi-mi:cyp8_yeast(display_long)|uniprotkb:CPR8(gene name)|psi-mi:CPR8(display_short)|uniprotkb:YNR028W(locus name)|uniprotkb:N3255(orf name)|uniprotkb:Rotamase CYP8(gene name synonym) psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341959|imex:IM-14275-2548 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005311|refseq:NP_014425.3|dip:DIP-4261N|mint:P53728|ensemblfungi:YNR028W(gene)|ensemblfungi:YNR028W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR029000 refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:PWJO9W+2WFHhC6Fl3xoH0rw9a2w559292 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 intact-crc:788E302BEE971A09|rigid:JO4iAqJH7BWFhcjHjmtyNZykq8U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54858 uniprotkb:Q03687 intact:EBI-6042|uniprotkb:D6VS54|ensemblfungi:YDR068W intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W psi-mi:dos2_yeast(display_long)|uniprotkb:D4267(orf name)|uniprotkb:YD8554.01(orf name)|uniprotkb:YD9609.22(orf name)|uniprotkb:DOS2(gene name)|psi-mi:DOS2(display_short)|uniprotkb:YDR068W(locus name) psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341970|imex:IM-14275-2549 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002475|refseq:NP_010353.3|dip:DIP-4785N|mint:P54858|ensemblfungi:YDR068W(gene)|ensemblfungi:YDR068W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR005607(BSD)|interpro:IPR035925 refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:/4fnAAPmC12DMUbUB8MVS9yjjeg559292 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 intact-crc:9AA5F71CF02FB052|rigid:rX13g5Qub9xFPHbAJitXfdj5Baw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03687 uniprotkb:Q03687 intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341981|imex:IM-14275-2550 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 intact-crc:9A1C77950E1EA7C4|rigid:UICpS/m3aqPNGCb3D/p4WMqVYGs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03687 uniprotkb:Q03860 intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6341992|imex:IM-14275-2551 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) - crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:7062245A71C554C6|rigid:sCK/TXflcv6kIkvOI49bQzGTQQE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03687 uniprotkb:Q12057 intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W intact:EBI-29838|uniprotkb:D6W2G4|ensemblfungi:YOR104W psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:pin2_yeast(display_long)|uniprotkb:PIN2(gene name)|psi-mi:PIN2(display_short)|uniprotkb:YOR3214W(orf name)|uniprotkb:YOR104W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342003|imex:IM-14275-2552 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) sgd:S000005630|refseq:NP_014747.1|dip:DIP-4459N|mint:Q12057|ensemblfungi:YOR104W(gene)|ensemblfungi:YOR104W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|interpro:IPR037504 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 rogid:Zk6iUcpP++MEXuhKZ79TMOYQYqM559292 intact-crc:69767FA35DE5D12B|rigid:MlVOIL7YOtcHoKzAxfwdbidbY8o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03687 uniprotkb:Q12114 intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W intact:EBI-4640|uniprotkb:D6VYX2|ensemblfungi:YLR330W psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:chs5_yeast(display_long)|uniprotkb:CHS5(gene name)|psi-mi:CHS5(display_short)|uniprotkb:CAL3(gene name synonym)|uniprotkb:YLR330W(locus name)|uniprotkb:L8543.18(orf name)|uniprotkb:Protein CAL3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342014|imex:IM-14275-2553 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) refseq:NP_013434.1|sgd:S000004322|dip:DIP-8073N|mint:Q12114|ensemblfungi:YLR330W(gene)|ensemblfungi:YLR330W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006039"(cell wall chitin catabolic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034044"(exomer complex)|go:"GO:0043332"(mating projection tip)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001357(BRCT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031669|interpro:IPR031673|interpro:IPR036116|interpro:IPR036420|rcsb pdb:4IN3|rcsb pdb:4WJW|rcsb pdb:4YG8 psi-mi:"MI:0469"(intact) - crc64:FA92741B862814C2 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 rogid:iHvfW3fNLv3HLj4Ihya1Vyt0X7I559292 intact-crc:73936B8CA048C75B|rigid:7GOHUZzTK8a1dNHRDIoNrmsCiLc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03687 uniprotkb:Q12270 intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342025|imex:IM-14275-2554 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:CB4531E5FE2FE9D1|rigid:Nb2Iz/SFJnDAMWjUl6cduZdWKgs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92331 uniprotkb:Q03687 intact:EBI-20483|uniprotkb:Q08483|uniprotkb:D6W2D1|uniprotkb:E9P8U6|ensemblfungi:YOR069W intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W psi-mi:vps5_yeast(display_long)|uniprotkb:VPS5(gene name)|psi-mi:VPS5(display_short)|uniprotkb:GRD2(gene name synonym)|uniprotkb:PEP10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 5(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 10(gene name synonym)|uniprotkb:VPT5(gene name synonym)|uniprotkb:YOR29-20(orf name)|uniprotkb:YOR069W(locus name) psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342036|imex:IM-14275-2555 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014712.2|sgd:S000005595|ensemblfungi:YOR069W(gene)|ensemblfungi:YOR069W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0005768"(endosome)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|interpro:IPR001683(Phox-like)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028648|interpro:IPR035803|interpro:IPR036871|interpro:IPR037868|dip:DIP-1740N|mint:Q92331 refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5aPSkQUJV1sfIc9Ql+wMP74Y3QI559292 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 intact-crc:61AE7BDCB5A21A39|rigid:5CiDw0a3I8mJqQ6QzmRF/kTzFYM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03697 uniprotkb:P09620 intact:EBI-27776|uniprotkb:D6VZD7|ensemblfungi:YML038C intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:ymd8_yeast(display_long)|uniprotkb:YML038C(locus name)|uniprotkb:YMD8(gene name)|psi-mi:YMD8(display_short) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342047|imex:IM-14275-2556 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013674.1|sgd:S000004502|dip:DIP-1312N|mint:Q03697|ensemblfungi:YML038C(gene)|ensemblfungi:YML038C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005338"(nucleotide-sugar transmembrane transporter activity)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015297"(antiporter activity)|go:"GO:0015780"(nucleotide-sugar transmembrane transport)|go:"GO:0015786"(UDP-glucose transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030663"(COPI-coated vesicle membrane)|interpro:IPR004853(Protein of unknown function DUF250) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) crc64:37A03543D3AB695E - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:i2Fqb84s31vBiayw4lJW8o3S3WU559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:8A7D2C8DC7CABDB9|rigid:e66jwEPbgfcnp9Jl1ibIXP7+cRo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03768 uniprotkb:P33892 intact:EBI-7618|uniprotkb:D6VSD4|ensemblfungi:YDR152W intact:EBI-7442|uniprotkb:D6VTV8|ensemblfungi:YGL195W psi-mi:gir2_yeast(display_long)|uniprotkb:GIR2(gene name)|psi-mi:GIR2(display_short)|uniprotkb:YDR152W(locus name)|uniprotkb:YD8358.08(orf name)|uniprotkb:DFRP2(gene name synonym)|uniprotkb:DRG family-regulatory protein 2(gene name synonym)|uniprotkb:Genetically interacts with ribosomal genes protein 2(gene name synonym) psi-mi:gcn1_yeast(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:General control non-derepressible protein 1(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym)|uniprotkb:G1318(orf name)|uniprotkb:YGL195W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342058|imex:IM-14275-2557 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002559|refseq:NP_010436.3|mint:Q03768|dip:DIP-1751N|ensemblfungi:YDR152W(gene)|ensemblfungi:YDR152W_mRNA(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR006575(RWD)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR040213 sgd:S000003163|refseq:NP_011320.3|mint:P33892|dip:DIP-2344N|ensemblfungi:YGL195W(gene)|ensemblfungi:YGL195W_mRNA(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071264"(positive regulation of translational initiation in response to starvation)|go:"GO:0072755"(cellular response to benomyl)|go:"GO:0140469"(GCN2-mediated signaling)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1990451"(cellular stress response to acidic pH)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR022716|interpro:IPR033173|interpro:IPR034085 psi-mi:"MI:0469"(intact) crc64:CE09A067388638ED crc64:980FDD03753E9D1C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2gb8Bf2IGl8RoOmNcIvEMlmgeTE559292 rogid:WPYtEB/xjy4g2cJFwhe+2teVYVk559292 intact-crc:57D7146D28B4A086|rigid:6WIHplwyY+5EbN3smomI0jyxfR4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25847 uniprotkb:Q03782 intact:EBI-11352|uniprotkb:Q12423|ensemblfungi:YOL090W|uniprotkb:D6W1X8 intact:EBI-627|uniprotkb:D6VSM1|ensemblfungi:YDR240C psi-mi:msh2_yeast(display_long)|uniprotkb:MSH2(gene name)|psi-mi:MSH2(display_short)|uniprotkb:YOL090W(locus name)|uniprotkb:O0935(orf name)|uniprotkb:MutS protein homolog 2(gene name synonym) psi-mi:snu56_yeast(display_long)|uniprotkb:YDR240C(locus name)|uniprotkb:SNU56(gene name)|psi-mi:SNU56(display_short)|uniprotkb:MUD10(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342069|imex:IM-14275-2558 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOL090W(gene)|ensemblfungi:YOL090W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000735"(removal of nonhomologous ends)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0006312"(mitotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043111"(replication fork arrest)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR032642|interpro:IPR036187|interpro:IPR036678|reactome:R-SCE-5358565|reactome:R-SCE-5358606|go:"GO:0032300"(mismatch repair complex)|refseq:NP_014551.1|sgd:S000005450|mint:P25847|dip:DIP-2415N sgd:S000002648|refseq:NP_010526.1|dip:DIP-6514N|mint:Q03782|ensemblfungi:YDR240C(gene)|ensemblfungi:YDR240C_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR043954|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X psi-mi:"MI:0469"(intact) crc64:43FFD8A640138AE4 crc64:5E0C7A1FD577808F figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:PNwekSiaI58qR+dPZZQW5UNRJ+4559292 rogid:gz3aUh/8pFF7Yn8XS9gdhSWrVNs559292 intact-crc:D7079D6CBB11C445|rigid:ClBjdoBQMDUs7tHi+ahQjvhAyzU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33895 uniprotkb:Q03782 intact:EBI-12377|uniprotkb:Q6B1X5|ensemblfungi:YOL069W|uniprotkb:D6W1Z8 intact:EBI-627|uniprotkb:D6VSM1|ensemblfungi:YDR240C psi-mi:nuf2_yeast(display_long)|uniprotkb:YOL069W(locus name)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short) psi-mi:snu56_yeast(display_long)|uniprotkb:YDR240C(locus name)|uniprotkb:SNU56(gene name)|psi-mi:SNU56(display_short)|uniprotkb:MUD10(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342080|imex:IM-14275-2559 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOL069W(gene)|ensemblfungi:YOL069W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005816"(spindle pole body)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|rcsb pdb:5TCS|rcsb pdb:5TD8|go:"GO:0045132"(meiotic chromosome segregation)|refseq:NP_014572.1|sgd:S000005430|mint:P33895|dip:DIP-1481N sgd:S000002648|refseq:NP_010526.1|dip:DIP-6514N|mint:Q03782|ensemblfungi:YDR240C(gene)|ensemblfungi:YDR240C_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR043954|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X psi-mi:"MI:0469"(intact) - crc64:5E0C7A1FD577808F figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oof/8nhKWQCx5bp4lvc7f33OO+0559292 rogid:gz3aUh/8pFF7Yn8XS9gdhSWrVNs559292 intact-crc:4F53D17C9AD1BC71|rigid:CzFtjuOVJQGTEwVM5m0ekxdQQiI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03835 uniprotkb:P38235 intact:EBI-22178|uniprotkb:D6VS83|ensemblfungi:YDR098C intact:EBI-21449|uniprotkb:D6VQ52|uniprotkb:Q6Q5P3|ensemblfungi:YBR053C psi-mi:glrx3_yeast(display_long)|uniprotkb:YD8557.05C(orf name)|uniprotkb:GRX3(gene name)|psi-mi:GRX3(display_short)|uniprotkb:YDR098C(locus name) psi-mi:ybq3_yeast(display_long)|uniprotkb:YBR0506(orf name)|uniprotkb:YBR053C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342091|imex:IM-14275-2560 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002505|refseq:NP_010383.4|dip:DIP-1350N|mint:Q03835|ensemblfungi:YDR098C(gene)|ensemblfungi:YDR098C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097573"(glutathione oxidoreductase activity)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR033658|interpro:IPR036249|rcsb pdb:3D6I|rcsb pdb:5Y4U refseq:NP_009609.1|sgd:S000000257|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013658(SMP-30/Gluconolaconase/LRE-like region)|mint:P38235|ensemblfungi:YBR053C(gene)|ensemblfungi:YBR053C_mRNA(transcript)|go:"GO:0004341"(gluconolactonase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0019853"(L-ascorbic acid biosynthetic process) psi-mi:"MI:0469"(intact) crc64:8CC1A04EC1E7DAB3 - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2015/11/09 rogid:Vjth+XO73fWvOUEPxBfvqKS+V0c559292 rogid:TStDtjZsqdqErK7CCygavX4ly+U559292 intact-crc:E8C566467D93C941|rigid:wXLtANDCtwPVfwZRAS2Jskz3W+k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03860 uniprotkb:P09620 intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342102|imex:IM-14275-2561 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) crc64:395F700FBB14C569 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:115CC6499E34BAE5|rigid:5/nljQ0tKADopmvNsn/GHnC3UwM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:Q03860 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342113|imex:IM-14275-2562 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:439005B56672DE6A|rigid:jEZn0i2X1B33yTriQ0xpafrZ/Ew false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03860 uniprotkb:P19146 intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W intact:EBI-2820|uniprotkb:A2TBP3|uniprotkb:D6VRL1|ensemblfungi:YDL137W psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:arf2_yeast(display_long)|uniprotkb:ARF2(gene name)|psi-mi:ARF2(display_short)|uniprotkb:D2165(orf name)|uniprotkb:YDL137W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342124|imex:IM-14275-2563 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) refseq:NP_010144.1|sgd:S000002296|dip:DIP-2215N|mint:P19146|ensemblfungi:YDL137W(gene)|ensemblfungi:YDL137W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:1MR3|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 psi-mi:"MI:0469"(intact) crc64:395F700FBB14C569 crc64:7E43FF792E8D64E8 figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 rogid:I4V9cXleaZ2sAE2DXGKt8zpAPzw559292 intact-crc:832F0A1D6A01CC50|rigid:1OQrR17a8j6a0kYDfne+iGZYJ+Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:Q03860 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342135|imex:IM-14275-2564 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) - crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:F63DB1C9CC3CE4C6|rigid:2imZFcoNm9x9zbCXR1n9jd4vraA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25361 uniprotkb:Q03860 intact:EBI-21909|uniprotkb:D6VR52|ensemblfungi:YCR043C intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:yct3_yeast(display_long)|uniprotkb:YCR43C(orf name)|uniprotkb:YCR725(orf name)|uniprotkb:YCR043C(locus name) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342146|imex:IM-14275-2565 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000639|refseq:NP_009972.1|mint:P25361|ensemblfungi:YCR043C(gene)|ensemblfungi:YCR043C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0043332"(mating projection tip) sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) - crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:bEMtsAa5vCsWqGOiXwBK40Pa0xQ559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:FFFD181FF3AEBB4E|rigid:iEv5ZUHRW8HQawmq4DVJWPu8x+8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32319 uniprotkb:Q03860 intact:EBI-13123|uniprotkb:D6VPY3|ensemblfungi:YBL017C intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:vps10_yeast(display_long)|uniprotkb:PEP1(gene name)|psi-mi:PEP1(display_short)|uniprotkb:Vacuolar carboxypeptidase sorting receptor VPS10(gene name synonym)|uniprotkb:Carboxypeptidase Y receptor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 1(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 1(gene name synonym)|uniprotkb:Sortilin VPS10(gene name synonym)|uniprotkb:VPS10(gene name synonym)|uniprotkb:VPT1(gene name synonym)|uniprotkb:YBL03.22(orf name)|uniprotkb:YBL0302(orf name)|uniprotkb:YBL017C(locus name) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342157|imex:IM-14275-2566 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009536.1|sgd:S000000113|mint:P32319|dip:DIP-5900N|ensemblfungi:YBL017C(gene)|ensemblfungi:YBL017C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000423"(mitophagy)|go:"GO:0000425"(pexophagy)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048203"(vesicle targeting, trans-Golgi to endosome)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR036278 sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) crc64:C778A0400612ECF4 crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dYYsekAaDw4SzmEUSe5tYb5a43M559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:E59F6AF266500AA1|rigid:9RjvOxYy9z0wSmmIQMjPpF1LDlE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32386 uniprotkb:Q03860 intact:EBI-21511|uniprotkb:Q07882|uniprotkb:D6VXW0|ensemblfungi:YLL048C intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:ybt1_yeast(display_long)|uniprotkb:YBT1(gene name)|psi-mi:YBT1(display_short)|uniprotkb:BAT1(gene name synonym)|uniprotkb:YLL048C(locus name) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342168|imex:IM-14275-2567 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013052.1|sgd:S000003971|mint:P32386|dip:DIP-6474N|ensemblfungi:YLL048C(gene)|ensemblfungi:YLL048C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006816"(calcium ion transport)|go:"GO:0015718"(monocarboxylic acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033285"(ATPase-coupled monocarboxylic acid transmembrane transporter activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) crc64:E71D3D57A3013C38 crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:b0Cz526nha/7DJPmG1uADmBnNPA559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:9EF4BDB89686B425|rigid:6dFFeRUzYhOWF7Fe2aVQYUyU4UQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03860 uniprotkb:P32465 intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342179|imex:IM-14275-2568 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N psi-mi:"MI:0469"(intact) crc64:395F700FBB14C569 - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 intact-crc:ED344F156757F71C|rigid:b2GxEarJwRgjZdqVgDEAxuIl4Vg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03860 uniprotkb:P35845 intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W intact:EBI-12611|uniprotkb:P39555|uniprotkb:P80234|uniprotkb:Q86ZC4|uniprotkb:Q86ZS1|uniprotkb:D6VPN6|ensemblfungi:YAR042W psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:osh1_yeast(display_long)|uniprotkb:SWH1(gene name)|psi-mi:SWH1(display_short)|uniprotkb:OSH1(gene name synonym)|uniprotkb:YAR044W(orf name)|uniprotkb:YAR042W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342190|imex:IM-14275-2569 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) ensemblfungi:YAR042W(gene)|ensemblfungi:YAR042W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0005829"(cytosol)|go:"GO:0008289"(lipid binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR036770|interpro:IPR037239|rcsb pdb:5H28|rcsb pdb:5H2C|reactome:R-SCE-192105|refseq:NP_009421.3|sgd:S000000081|mint:P35845|dip:DIP-6839N psi-mi:"MI:0469"(intact) crc64:395F700FBB14C569 - figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 rogid:Uag2eKjjL7ua+oy/CfVq+g9FORU559292 intact-crc:8ECA9A92663A0534|rigid:0r2xDKN5PmbvMnaPGxZbVEqM4XU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36164 uniprotkb:Q03860 intact:EBI-26527|uniprotkb:D6VXE8|ensemblfungi:YKR088C intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:tvp38_yeast(display_long)|uniprotkb:YKR408(orf name)|uniprotkb:YKR088C(locus name)|uniprotkb:TVP38(gene name)|psi-mi:TVP38(display_short)|uniprotkb:TLG2-vesicle protein of 38 kDa(gene name synonym) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342201|imex:IM-14275-2570 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001796|refseq:NP_013014.3|mint:P36164|dip:DIP-5167N|interpro:IPR032816|ensemblfungi:YKR088C(gene)|ensemblfungi:YKR088C_mRNA(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0005737"(cytoplasm)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane) sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) crc64:7EA95DD4E5AF77FE crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wNtRh3eKqVkQKwO9QmrJHjSSdnk559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:FE9D1545DA383534|rigid:cOuH3OztUQ1odno4Ai+zJk6gjV8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38166 uniprotkb:Q03860 intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342212|imex:IM-14275-2571 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166 sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) crc64:1BF971749814382C crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:5F6C0D02A0CB3BD4|rigid:T7XAynnpE00EeDrVGnrakyh4HCw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03860 uniprotkb:P38929 intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342223|imex:IM-14275-2572 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 psi-mi:"MI:0469"(intact) crc64:395F700FBB14C569 crc64:5BD9ECFF8508F396 figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 intact-crc:EA95C248639B3DA7|rigid:6iTUGTacxBOcW9y7qWjmkKL7sRY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39010 uniprotkb:Q03860 intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342234|imex:IM-14275-2573 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) - crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:665A837830E8BF55|rigid:BMRnPQRcxUweGt3XZhHuEEDpUL4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03860 uniprotkb:P40094 intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W intact:EBI-16605|ensemblfungi:YER157W|uniprotkb:D3DM64 psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:cog3_yeast(display_long)|uniprotkb:COG3(gene name)|psi-mi:COG3(display_short)|uniprotkb:GRD20(gene name synonym)|uniprotkb:SEC34(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 3(gene name synonym)|uniprotkb:Protein SEC34(gene name synonym)|uniprotkb:YER157W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342245|imex:IM-14275-2574 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) ensemblfungi:YER157W(gene)|ensemblfungi:YER157W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR007265(Sec34-like protein)|refseq:NP_011084.1|sgd:S000000959|dip:DIP-4728N|mint:P40094 psi-mi:"MI:0469"(intact) crc64:395F700FBB14C569 crc64:C7AFBE99010FE571 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 rogid:R2r0ZW+nxrykdTHq1cJy9zOmvHo559292 intact-crc:A56AEF8FC7E533D6|rigid:CJ+WAlTvqT/zB1qiqs+Hz+mPcSo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40540 uniprotkb:Q03860 intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342256|imex:IM-14275-2575 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) crc64:6DBEEEE7722203B0 crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:4DD11F3D0006497A|rigid:ntFS+mOcLL9RVpYrnnwLLCFDNfA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41810 uniprotkb:Q03860 intact:EBI-4869|uniprotkb:Q03779|uniprotkb:D6VSL9|ensemblfungi:YDR238C intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:copb_yeast(display_long)|uniprotkb:SEC26(gene name)|psi-mi:SEC26(display_short)|uniprotkb:YDR238C(locus name)|uniprotkb:YD8419.05C(orf name)|uniprotkb:Beta-coat protein(gene name synonym) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342267|imex:IM-14275-2576 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002646|refseq:NP_010524.3|dip:DIP-6467N|mint:P41810|ensemblfungi:YDR238C(gene)|ensemblfungi:YDR238C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|reactome:R-SCE-6798695|reactome:R-SCE-6807878|reactome:R-SCE-6811434 sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) crc64:885420DB026BCFA3 crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZfLp1BUmvVuTiXn7/Zbf/3m6VtE559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:40E1CF8C1FED716D|rigid:z3Hw5IeVS1YcLin1z6Mfpzs9aVk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41811 uniprotkb:Q03860 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342278|imex:IM-14275-2577 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) crc64:6A5E50BBEB02CB58 crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:41E708F8AAB4E92F|rigid:fBMBv746MEMXmMGNAt0Z4nkWgVY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03860 uniprotkb:P46989 intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342289|imex:IM-14275-2578 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:395F700FBB14C569 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 intact-crc:A299E5FA602A3C2E|rigid:9rH2bACKabJVQs5yCcADVbm7TmA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54858 uniprotkb:Q03860 intact:EBI-6042|uniprotkb:D6VS54|ensemblfungi:YDR068W intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:dos2_yeast(display_long)|uniprotkb:D4267(orf name)|uniprotkb:YD8554.01(orf name)|uniprotkb:YD9609.22(orf name)|uniprotkb:DOS2(gene name)|psi-mi:DOS2(display_short)|uniprotkb:YDR068W(locus name) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342300|imex:IM-14275-2579 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002475|refseq:NP_010353.3|dip:DIP-4785N|mint:P54858|ensemblfungi:YDR068W(gene)|ensemblfungi:YDR068W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR005607(BSD)|interpro:IPR035925 sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) - crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:/4fnAAPmC12DMUbUB8MVS9yjjeg559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:70DBA4D38FF44350|rigid:wF3OA4agDXlAXrVb8D+ca50z258 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03687 uniprotkb:Q03860 intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342311|imex:IM-14275-2580 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) - crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:F1A3DE626FA86048|rigid:sCK/TXflcv6kIkvOI49bQzGTQQE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03730 uniprotkb:Q03860 intact:EBI-27739|uniprotkb:Q6B2K7|uniprotkb:D6VZF6|ensemblfungi:YML018C intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:ymb8_yeast(display_long)|uniprotkb:YML018C(locus name) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342322|imex:IM-14275-2581 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004480|refseq:NP_013694.1|dip:DIP-4953N|mint:Q03730|ensemblfungi:YML018C(gene)|ensemblfungi:YML018C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane) sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) crc64:DEC5C3EEF293F5ED crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4WxEFdhqbP7pcRcTLeFHljCVQ34559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:92E3AADD745C5295|rigid:R/j0wHfNXiRnBjq0wqs0R516abY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03860 uniprotkb:Q03860 intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342333|imex:IM-14275-2582 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) crc64:395F700FBB14C569 crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:7E346A457DF32042|rigid:FomfCfnb1D+03wb7ITIUVJp0Kg4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06815 uniprotkb:Q03860 intact:EBI-33784|uniprotkb:D6W481|ensemblfungi:YPR079W intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:mrl1_yeast(display_long)|uniprotkb:YPR079W(locus name)|uniprotkb:MRL1(gene name)|psi-mi:MRL1(display_short) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342344|imex:IM-14275-2583 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015404.1|sgd:S000006283|mint:Q06815|dip:DIP-2873N|ensemblfungi:YPR079W(gene)|ensemblfungi:YPR079W_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007034"(vacuolar transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR036607|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) - crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:PFMxRfVBupoO0p3pb+BB5H2fidg559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:98B3B19B6828746C|rigid:xVqak3XEU4yaldzzL9uLAq9VDWo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07528 uniprotkb:Q03860 intact:EBI-36894|uniprotkb:D6VRN7|ensemblfungi:YDL113C intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:atg20_yeast(display_long)|uniprotkb:ATG20(gene name)|psi-mi:ATG20(display_short)|uniprotkb:YDL113C(locus name)|uniprotkb:Cytoplasm to vacuole targeting protein 20(gene name synonym)|uniprotkb:Sorting nexin-42(gene name synonym)|uniprotkb:CVT20(gene name synonym)|uniprotkb:SNX42(gene name synonym) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342355|imex:IM-14275-2584 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010170.1|sgd:S000002271|mint:Q07528|dip:DIP-1593N|ensemblfungi:YDL113C(gene)|ensemblfungi:YDL113C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034498"(early endosome to Golgi transport)|interpro:IPR001683(Phox-like)|interpro:IPR027267|interpro:IPR036871|interpro:IPR044106 sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) crc64:160977A8BECB6D93 crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BWykOKWex5TB/nRzSUOXdZlM8yk559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:E0E14C635065068C|rigid:2fpZIJNIoio7KmAMKQPgMZf1Dc8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03860 uniprotkb:Q12016 intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W intact:EBI-29309|uniprotkb:D6W1T9|ensemblfungi:YOL129W psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:vps68_yeast(display_long)|uniprotkb:YOL129W(locus name)|uniprotkb:VPS68(gene name)|psi-mi:VPS68(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342366|imex:IM-14275-2585 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) refseq:NP_014512.1|sgd:S000005489|dip:DIP-1732N|mint:Q12016|ensemblfungi:YOL129W(gene)|ensemblfungi:YOL129W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0034424"(Vps55/Vps68 complex)|interpro:IPR007919(Protein of unknown function UPF0220) psi-mi:"MI:0469"(intact) crc64:395F700FBB14C569 crc64:4B21C846AB3BA2A7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 rogid:I6sUyfNcLBsFG3OtDUfEqohxLB4559292 intact-crc:8DE66C66ECB02A82|rigid:GgQMQtu8/lDhlNPAbFq/oNy3BQE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03860 uniprotkb:Q12270 intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342377|imex:IM-14275-2586 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) crc64:395F700FBB14C569 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:C5137FFAF2199D55|rigid:sitghYqjSF4eyZzFrKmUIxctKQQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92331 uniprotkb:Q03860 intact:EBI-20483|uniprotkb:Q08483|uniprotkb:D6W2D1|uniprotkb:E9P8U6|ensemblfungi:YOR069W intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:vps5_yeast(display_long)|uniprotkb:VPS5(gene name)|psi-mi:VPS5(display_short)|uniprotkb:GRD2(gene name synonym)|uniprotkb:PEP10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 5(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 10(gene name synonym)|uniprotkb:VPT5(gene name synonym)|uniprotkb:YOR29-20(orf name)|uniprotkb:YOR069W(locus name) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342388|imex:IM-14275-2587 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014712.2|sgd:S000005595|ensemblfungi:YOR069W(gene)|ensemblfungi:YOR069W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0005768"(endosome)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|interpro:IPR001683(Phox-like)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028648|interpro:IPR035803|interpro:IPR036871|interpro:IPR037868|dip:DIP-1740N|mint:Q92331 sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) - crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5aPSkQUJV1sfIc9Ql+wMP74Y3QI559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:6FF835C3B9946EBD|rigid:PoGRR8GvfnpdpurDxli85IQs3LI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38344 uniprotkb:Q03862 intact:EBI-21136|uniprotkb:D6VQR3|ensemblfungi:YBR267W intact:EBI-31385|uniprotkb:D6VS88|ensemblfungi:YDR101C psi-mi:rei1_yeast(display_long)|uniprotkb:REI1(gene name)|psi-mi:REI1(display_short)|uniprotkb:Required for isotropic bud growth protein 1(gene name synonym)|uniprotkb:pre-60S factor REI1(gene name synonym)|uniprotkb:YBR1736(orf name)|uniprotkb:YBR267W(locus name) psi-mi:arx1_yeast(display_long)|uniprotkb:Associated with ribosomal export complex protein 1(gene name synonym)|uniprotkb:ARX1(gene name)|psi-mi:ARX1(display_short)|uniprotkb:YD8557.10c(orf name)|uniprotkb:YDR101C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342399|imex:IM-14275-2588 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009825.4|sgd:S000000471|mint:P38344|dip:DIP-6347N|rcsb pdb:6RZZ|rcsb pdb:5APN|ensemblfungi:YBR267W(gene)|ensemblfungi:YBR267W_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR040025|interpro:IPR041661 refseq:NP_010386.1|sgd:S000002508|dip:DIP-5819N|mint:Q03862|ensemblfungi:YDR101C(gene)|ensemblfungi:YDR101C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0046872"(metal ion binding)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR036005|interpro:IPR036388|rcsb pdb:3JCT|rcsb pdb:4V7F|rcsb pdb:4V8T|rcsb pdb:5APN|rcsb pdb:5APO|rcsb pdb:5JCS|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6RZZ|rcsb pdb:6YLG|rcsb pdb:6YLH|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) crc64:D01AA8FFDF4A0BAC crc64:E68A7896FAFA6A0C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YxMyWWxJUH2Pk41X+98x8jcnqhc559292 rogid:td4xQ4tAQGk4eK1saQr7x3whlqs559292 intact-crc:2102D94798A33E3A|rigid:qsecFF24bE80Cv+fKn6qRgrkqYQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:Q03880 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-27252|uniprotkb:D6VZU6|ensemblfungi:YMR123W psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:pkr1_yeast(display_long)|uniprotkb:PKR1(gene name)|psi-mi:PKR1(display_short)|uniprotkb:YM8564.05(orf name)|uniprotkb:YMR123W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342410|imex:IM-14275-2589 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_013842.1|sgd:S000004730|mint:Q03880|dip:DIP-4436N|ensemblfungi:YMR123W(gene)|ensemblfungi:YMR123W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|interpro:IPR013945(Endoplasmic reticulum, protein Pkr1) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:f1EeHmyCkgLFK7lWvdeZa/iNMW8559292 intact-crc:D47A71DEE2E6EB20|rigid:iMmg3w+r85zGLLj3v7c+6oW13Pw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41806 uniprotkb:Q03880 intact:EBI-20323|uniprotkb:D6VUN7|uniprotkb:Q6Q5Q3|ensemblfungi:YGR105W intact:EBI-27252|uniprotkb:D6VZU6|ensemblfungi:YMR123W psi-mi:vma21_yeast(display_long)|uniprotkb:VMA21(gene name)|psi-mi:VMA21(display_short)|uniprotkb:YGR105W(locus name) psi-mi:pkr1_yeast(display_long)|uniprotkb:PKR1(gene name)|psi-mi:PKR1(display_short)|uniprotkb:YM8564.05(orf name)|uniprotkb:YMR123W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342421|imex:IM-14275-2590 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003337|refseq:NP_011619.3|ensemblfungi:YGR105W(gene)|ensemblfungi:YGR105W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|interpro:IPR019013|dip:DIP-5526N|mint:P41806 refseq:NP_013842.1|sgd:S000004730|mint:Q03880|dip:DIP-4436N|ensemblfungi:YMR123W(gene)|ensemblfungi:YMR123W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|interpro:IPR013945(Endoplasmic reticulum, protein Pkr1) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ailhh4PtjuOy5Jiwx8aN7cHFddk559292 rogid:f1EeHmyCkgLFK7lWvdeZa/iNMW8559292 intact-crc:54BA56847996C24E|rigid:fjWWuNVE//h9AE5Ws8ND9aApJRI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:Q03880 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-27252|uniprotkb:D6VZU6|ensemblfungi:YMR123W psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:pkr1_yeast(display_long)|uniprotkb:PKR1(gene name)|psi-mi:PKR1(display_short)|uniprotkb:YM8564.05(orf name)|uniprotkb:YMR123W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342432|imex:IM-14275-2591 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_013842.1|sgd:S000004730|mint:Q03880|dip:DIP-4436N|ensemblfungi:YMR123W(gene)|ensemblfungi:YMR123W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|interpro:IPR013945(Endoplasmic reticulum, protein Pkr1) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:f1EeHmyCkgLFK7lWvdeZa/iNMW8559292 intact-crc:D1ADC9EAA828C6E8|rigid:MG3vVHVtfoyHP586Y1WvkXExQ8I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03880 uniprotkb:Q05359 intact:EBI-27252|uniprotkb:D6VZU6|ensemblfungi:YMR123W intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A psi-mi:pkr1_yeast(display_long)|uniprotkb:PKR1(gene name)|psi-mi:PKR1(display_short)|uniprotkb:YM8564.05(orf name)|uniprotkb:YMR123W(locus name) psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342443|imex:IM-14275-2592 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013842.1|sgd:S000004730|mint:Q03880|dip:DIP-4436N|ensemblfungi:YMR123W(gene)|ensemblfungi:YMR123W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|interpro:IPR013945(Endoplasmic reticulum, protein Pkr1) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:f1EeHmyCkgLFK7lWvdeZa/iNMW8559292 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 intact-crc:6D11098DF1CEDCA2|rigid:RwFjYp3WM4TopPcM3Xvb4mVZ1LQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:Q03921 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-34442|uniprotkb:D6VSC4|ensemblfungi:YDR141C psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:dop1_yeast(display_long)|uniprotkb:DOP1(gene name)|psi-mi:DOP1(display_short)|uniprotkb:YD9302.17C(orf name)|uniprotkb:YDR141C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342454|imex:IM-14275-2593 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 refseq:NP_010425.1|sgd:S000002548|mint:Q03921|dip:DIP-2624N|ensemblfungi:YDR141C(gene)|ensemblfungi:YDR141C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0015031"(protein transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|interpro:IPR007249(Dopey, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040314 psi-mi:"MI:0469"(intact) - crc64:119459CD3785526C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:JnJT3q+lX1fzV4l4NMxlyqvb7Sg559292 intact-crc:84CA76FA2871103C|rigid:JNMix83zReiEu7vELbKEU446h+E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03921 uniprotkb:P19807 intact:EBI-34442|uniprotkb:D6VSC4|ensemblfungi:YDR141C intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:dop1_yeast(display_long)|uniprotkb:DOP1(gene name)|psi-mi:DOP1(display_short)|uniprotkb:YD9302.17C(orf name)|uniprotkb:YDR141C(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342465|imex:IM-14275-2594 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010425.1|sgd:S000002548|mint:Q03921|dip:DIP-2624N|ensemblfungi:YDR141C(gene)|ensemblfungi:YDR141C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0015031"(protein transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|interpro:IPR007249(Dopey, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040314 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) crc64:119459CD3785526C - figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:JnJT3q+lX1fzV4l4NMxlyqvb7Sg559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:63AAB21A73E94E1F|rigid:mvMAhbfodkQGDLoTGTmS4wh9tvQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03921 uniprotkb:P32465 intact:EBI-34442|uniprotkb:D6VSC4|ensemblfungi:YDR141C intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 psi-mi:dop1_yeast(display_long)|uniprotkb:DOP1(gene name)|psi-mi:DOP1(display_short)|uniprotkb:YD9302.17C(orf name)|uniprotkb:YDR141C(locus name) psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342476|imex:IM-14275-2595 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010425.1|sgd:S000002548|mint:Q03921|dip:DIP-2624N|ensemblfungi:YDR141C(gene)|ensemblfungi:YDR141C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0015031"(protein transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|interpro:IPR007249(Dopey, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040314 ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N psi-mi:"MI:0469"(intact) crc64:119459CD3785526C - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:JnJT3q+lX1fzV4l4NMxlyqvb7Sg559292 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 intact-crc:78A2FD76D1125DC5|rigid:8wTlOh96Umpwu1/u6qdwdKfRgmw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03921 uniprotkb:P38116 intact:EBI-34442|uniprotkb:D6VSC4|ensemblfungi:YDR141C intact:EBI-2869|uniprotkb:D6VQG0|ensemblfungi:YBR164C psi-mi:dop1_yeast(display_long)|uniprotkb:DOP1(gene name)|psi-mi:DOP1(display_short)|uniprotkb:YD9302.17C(orf name)|uniprotkb:YDR141C(locus name) psi-mi:arl1_yeast(display_long)|uniprotkb:ARL1(gene name)|psi-mi:ARL1(display_short)|uniprotkb:Arf-like GTPase 1(gene name synonym)|uniprotkb:ARF3(gene name synonym)|uniprotkb:YBR1216(orf name)|uniprotkb:YBR164C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342487|imex:IM-14275-2596 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010425.1|sgd:S000002548|mint:Q03921|dip:DIP-2624N|ensemblfungi:YDR141C(gene)|ensemblfungi:YDR141C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0015031"(protein transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|interpro:IPR007249(Dopey, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040314 refseq:NP_009723.3|sgd:S000000368|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P38116|ensemblfungi:YBR164C(gene)|ensemblfungi:YBR164C_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|rcsb pdb:1MOZ|reactome:R-SCE-6811440 psi-mi:"MI:0469"(intact) crc64:119459CD3785526C - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:JnJT3q+lX1fzV4l4NMxlyqvb7Sg559292 rogid:tU13jjaqDMJDBkGFFJL9FtB3x0U559292 intact-crc:76DDBDB109BCFDC4|rigid:yrb9o6afcXh10l2ezkdHSAVxqE4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03921 uniprotkb:P38310 intact:EBI-34442|uniprotkb:D6VSC4|ensemblfungi:YDR141C intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:dop1_yeast(display_long)|uniprotkb:DOP1(gene name)|psi-mi:DOP1(display_short)|uniprotkb:YD9302.17C(orf name)|uniprotkb:YDR141C(locus name) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342498|imex:IM-14275-2597 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010425.1|sgd:S000002548|mint:Q03921|dip:DIP-2624N|ensemblfungi:YDR141C(gene)|ensemblfungi:YDR141C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0015031"(protein transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|interpro:IPR007249(Dopey, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040314 refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) crc64:119459CD3785526C crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:JnJT3q+lX1fzV4l4NMxlyqvb7Sg559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:5D040D7A86A0D6BB|rigid:uGEQu01hFKvQIJXUq1Er4nWFzj4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:Q03921 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-34442|uniprotkb:D6VSC4|ensemblfungi:YDR141C psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:dop1_yeast(display_long)|uniprotkb:DOP1(gene name)|psi-mi:DOP1(display_short)|uniprotkb:YD9302.17C(orf name)|uniprotkb:YDR141C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342509|imex:IM-14275-2598 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_010425.1|sgd:S000002548|mint:Q03921|dip:DIP-2624N|ensemblfungi:YDR141C(gene)|ensemblfungi:YDR141C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0015031"(protein transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|interpro:IPR007249(Dopey, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040314 psi-mi:"MI:0469"(intact) - crc64:119459CD3785526C figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:JnJT3q+lX1fzV4l4NMxlyqvb7Sg559292 intact-crc:28D1610A543E0AEF|rigid:EOxJ/wvpP0D2W66XU6TVJE7OO8U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03921 uniprotkb:P53283 intact:EBI-34442|uniprotkb:D6VSC4|ensemblfungi:YDR141C intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:dop1_yeast(display_long)|uniprotkb:DOP1(gene name)|psi-mi:DOP1(display_short)|uniprotkb:YD9302.17C(orf name)|uniprotkb:YDR141C(locus name) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342520|imex:IM-14275-2599 author score:99.24 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010425.1|sgd:S000002548|mint:Q03921|dip:DIP-2624N|ensemblfungi:YDR141C(gene)|ensemblfungi:YDR141C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0015031"(protein transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|interpro:IPR007249(Dopey, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040314 refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:119459CD3785526C - figure legend:tables S3 and S4|author-confidence:99.24|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:JnJT3q+lX1fzV4l4NMxlyqvb7Sg559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 intact-crc:5CFB910F26785E69|rigid:Njkh0pF/ggsBTjlGULINdWDBC1I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03687 uniprotkb:Q03921 intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W intact:EBI-34442|uniprotkb:D6VSC4|ensemblfungi:YDR141C psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:dop1_yeast(display_long)|uniprotkb:DOP1(gene name)|psi-mi:DOP1(display_short)|uniprotkb:YD9302.17C(orf name)|uniprotkb:YDR141C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342531|imex:IM-14275-2600 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) refseq:NP_010425.1|sgd:S000002548|mint:Q03921|dip:DIP-2624N|ensemblfungi:YDR141C(gene)|ensemblfungi:YDR141C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0015031"(protein transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|interpro:IPR007249(Dopey, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040314 psi-mi:"MI:0469"(intact) - crc64:119459CD3785526C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 rogid:JnJT3q+lX1fzV4l4NMxlyqvb7Sg559292 intact-crc:64356ED1D9EDCA91|rigid:fd/2NA5CkO/ecpp9UG9l86uDgpA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03860 uniprotkb:Q03921 intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W intact:EBI-34442|uniprotkb:D6VSC4|ensemblfungi:YDR141C psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:dop1_yeast(display_long)|uniprotkb:DOP1(gene name)|psi-mi:DOP1(display_short)|uniprotkb:YD9302.17C(orf name)|uniprotkb:YDR141C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342542|imex:IM-14275-2601 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) refseq:NP_010425.1|sgd:S000002548|mint:Q03921|dip:DIP-2624N|ensemblfungi:YDR141C(gene)|ensemblfungi:YDR141C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0015031"(protein transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|interpro:IPR007249(Dopey, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040314 psi-mi:"MI:0469"(intact) crc64:395F700FBB14C569 crc64:119459CD3785526C figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 rogid:JnJT3q+lX1fzV4l4NMxlyqvb7Sg559292 intact-crc:6A6453AED5DBBE15|rigid:GHrxy2NtamoeOgJldHlqaXx91e8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31412 uniprotkb:Q03956 intact:EBI-20260|uniprotkb:D6VXK7|ensemblfungi:YKL080W intact:EBI-30629|uniprotkb:D6VSI4|ensemblfungi:YDR202C psi-mi:vatc_yeast(display_long)|uniprotkb:VMA5(gene name)|psi-mi:VMA5(display_short)|uniprotkb:VAT3(gene name synonym)|uniprotkb:VATC(gene name synonym)|uniprotkb:YKL410(orf name)|uniprotkb:YKL080W(locus name)|uniprotkb:Vacuolar proton pump subunit C(gene name synonym)|uniprotkb:V-ATPase 42 kDa subunit(gene name synonym) psi-mi:rav2_yeast(display_long)|uniprotkb:RAV2(gene name)|psi-mi:RAV2(display_short)|uniprotkb:YD9346.12C(orf name)|uniprotkb:YDR202C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342553|imex:IM-14275-2602 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012843.1|sgd:S000001563|ensemblfungi:YKL080W(gene)|ensemblfungi:YKL080W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004907(ATPase, V1 complex, subunit C)|interpro:IPR036132|rcsb pdb:1U7L|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4DL0|rcsb pdb:4EFA|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-4701N|mint:P31412 sgd:S000002610|refseq:NP_010488.1|dip:DIP-8529N|mint:Q03956|ensemblfungi:YDR202C(gene)|ensemblfungi:YDR202C_mRNA(transcript)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043291"(RAVE complex)|interpro:IPR028241 psi-mi:"MI:0469"(intact) crc64:0CD1B814046C377E - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:NBI0upCB5yxAyMQgccBcLhjZk8s559292 rogid:w6UimIdIhzCD4J+iGQJ4KEwVOew559292 intact-crc:4D37D209F778A330|rigid:vNHxKh3MbsMEyFdYWGn2qw6BzxQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03957 uniprotkb:P21304 intact:EBI-5230|uniprotkb:D6VX57|ensemblfungi:YKL139W intact:EBI-14328|uniprotkb:D6VYJ9|ensemblfungi:YLR196W psi-mi:ctk1_yeast(display_long)|uniprotkb:CTK1(gene name)|psi-mi:CTK1(display_short)|uniprotkb:CTD kinase subunit 1(gene name synonym)|uniprotkb:CTD kinase 58 kDa subunit(gene name synonym)|uniprotkb:YKL139W(locus name) psi-mi:pwp1_yeast(display_long)|uniprotkb:L8167.10(orf name)|uniprotkb:YLR196W(locus name)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342564|imex:IM-14275-2603 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012783.1|sgd:S000001622|dip:DIP-6631N|mint:Q03957|ensemblfungi:YKL139W(gene)|ensemblfungi:YKL139W_mRNA(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006413"(translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030332"(cyclin binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:7JV7 refseq:NP_013297.1|sgd:S000004186|ensemblfungi:YLR196W(gene)|ensemblfungi:YLR196W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR044285|mint:P21304|dip:DIP-4203N psi-mi:"MI:0469"(intact) crc64:9862EB10FD476F6B crc64:FC0189B289494AB5 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UAGFPi65iZmt4poaGbS4AKLhtkI559292 rogid:Q1nPXtlkpIw8JosaiYX0PSVNaSw559292 intact-crc:FCDE020B383BE718|rigid:od9DiNclT+iIyp3ZgKM6Nba8Nqs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03957 uniprotkb:P46675 intact:EBI-5230|uniprotkb:D6VX57|ensemblfungi:YKL139W intact:EBI-18471|uniprotkb:D6VY47|ensemblfungi:YLR045C psi-mi:ctk1_yeast(display_long)|uniprotkb:CTK1(gene name)|psi-mi:CTK1(display_short)|uniprotkb:CTD kinase subunit 1(gene name synonym)|uniprotkb:CTD kinase 58 kDa subunit(gene name synonym)|uniprotkb:YKL139W(locus name) psi-mi:stu2_yeast(display_long)|uniprotkb:STU2(gene name)|psi-mi:STU2(display_short)|uniprotkb:YLR045C(locus name)|uniprotkb:L2108(orf name)|uniprotkb:Suppressor of tubulin 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342575|imex:IM-14275-2604 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012783.1|sgd:S000001622|dip:DIP-6631N|mint:Q03957|ensemblfungi:YKL139W(gene)|ensemblfungi:YKL139W_mRNA(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006413"(translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030332"(cyclin binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:7JV7 go:"GO:0005938"(cell cortex)|refseq:NP_013146.1|sgd:S000004035|ensemblfungi:YLR045C(gene)|ensemblfungi:YLR045C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005816"(spindle pole body)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0061863"(microtubule plus end polymerase)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR034085|rcsb pdb:2QK1|rcsb pdb:4FFB|rcsb pdb:4U3J|rcsb pdb:6BL7|rcsb pdb:7KDF|dip:DIP-2462N|mint:P46675 psi-mi:"MI:0469"(intact) crc64:9862EB10FD476F6B crc64:7A49C3702E21C7BF figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UAGFPi65iZmt4poaGbS4AKLhtkI559292 rogid:MZSvgMGh+d1BYxGm4AEptyNQRfk559292 intact-crc:54D35CFBDC664425|rigid:ovGlzw4k5DT6UXB3mZPJAeNAPWE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03957 uniprotkb:Q06411 intact:EBI-5230|uniprotkb:D6VX57|ensemblfungi:YKL139W intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W psi-mi:ctk1_yeast(display_long)|uniprotkb:CTK1(gene name)|psi-mi:CTK1(display_short)|uniprotkb:CTD kinase subunit 1(gene name synonym)|uniprotkb:CTD kinase 58 kDa subunit(gene name synonym)|uniprotkb:YKL139W(locus name) psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342586|imex:IM-14275-2605 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012783.1|sgd:S000001622|dip:DIP-6631N|mint:Q03957|ensemblfungi:YKL139W(gene)|ensemblfungi:YKL139W_mRNA(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006413"(translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030332"(cyclin binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:7JV7 refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88 psi-mi:"MI:0469"(intact) crc64:9862EB10FD476F6B crc64:9986B547B9582338 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UAGFPi65iZmt4poaGbS4AKLhtkI559292 rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292 intact-crc:99D30A90BDDF4B53|rigid:831DQnFRwQPZdEs8dMt/AKh+AuY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23202 uniprotkb:Q04031 intact:EBI-20138|uniprotkb:D6W0W3|ensemblfungi:YNL229C intact:EBI-31091|uniprotkb:D6VT44|ensemblfungi:YDR412W psi-mi:ure2_yeast(display_long)|uniprotkb:URE2(gene name)|psi-mi:URE2(display_short)|uniprotkb:Disulfide reductase(gene name synonym)|uniprotkb:Glutathione peroxidase(gene name synonym)|uniprotkb:N1165(orf name)|uniprotkb:YNL229C(locus name) psi-mi:rrp17_yeast(display_long)|uniprotkb:RRP17(gene name)|psi-mi:RRP17(display_short)|uniprotkb:YDR412W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342597|imex:IM-14275-2606 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014170.1|sgd:S000005173|ensemblfungi:YNL229C(gene)|ensemblfungi:YNL229C_mRNA(transcript)|mint:P23202|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0010044"(response to aluminum ion)|go:"GO:0032447"(protein urmylation)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR017298(Prion URE2)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:1G6W|rcsb pdb:1G6Y|rcsb pdb:1HQO|rcsb pdb:1JZR|rcsb pdb:1K0A|rcsb pdb:1K0B|rcsb pdb:1K0C|rcsb pdb:1K0D|go:"GO:0003714"(transcription corepressor activity)|dip:DIP-1308N refseq:NP_010700.3|sgd:S000002820|dip:DIP-1264N|mint:Q04031|ensemblfungi:YDR412W(gene)|ensemblfungi:YDR412W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|interpro:IPR019186 psi-mi:"MI:0469"(intact) crc64:2C628976034B0F1C crc64:A61BB3AE3838CBAF figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jjsWygBsEp8axNurMa3pxPMQJ2k559292 rogid:aC8bLzE4Tlvguem648OlXxm5iR0559292 intact-crc:427AC073CAC90607|rigid:LfNYRVJ3bPp6M2XiPm3SGxypXTQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04052 uniprotkb:Q02046 intact:EBI-2045173|uniprotkb:D6VT51|ensemblfungi:YDR421W intact:EBI-2045181|uniprotkb:D6VXE0|ensemblfungi:YKR080W psi-mi:aro80_yeast(display_long)|uniprotkb:D9461.10(orf name)|uniprotkb:YDR421W(locus name)|uniprotkb:ARO80(gene name)|psi-mi:ARO80(display_short) psi-mi:mtd1_yeast(display_long)|uniprotkb:YKR400(orf name)|uniprotkb:YKR080W(locus name)|uniprotkb:MTD1(gene name)|psi-mi:MTD1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342608|imex:IM-14275-2607 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010709.1|sgd:S000002829|dip:DIP-1012N|mint:Q04052|ensemblfungi:YDR421W(gene)|ensemblfungi:YDR421W_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006559"(L-phenylalanine catabolic process)|go:"GO:0006569"(tryptophan catabolic process)|go:"GO:0006572"(tyrosine catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009074"(aromatic amino acid family catabolic process)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR036864 sgd:S000001788|refseq:NP_013006.3|dip:DIP-730N|mint:Q02046|ensemblfungi:YKR080W(gene)|ensemblfungi:YKR080W_mRNA(transcript)|go:"GO:0004487"("methylenetetrahydrofolate dehydrogenase (NAD+) activity")|go:"GO:0004488"("methylenetetrahydrofolate dehydrogenase (NADP+) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0009396"(folic acid-containing compound biosynthetic process)|interpro:IPR000672(Tetrahydrofolate dehydrogenase/cyclohydrolase)|interpro:IPR020630|interpro:IPR020631|interpro:IPR035812|interpro:IPR036291|rcsb pdb:1EDZ|rcsb pdb:1EE9 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:08pfqZayEoT2Z2+yi28BX4WEK90559292 rogid:xAOzw/g5xSBjpNJuVTxsxTeWAEI559292 intact-crc:E59193D0B2522411|rigid:P0NUi3mR56YoqLeWm+qsYb8oqIs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04080 uniprotkb:P38875 intact:EBI-7777|uniprotkb:D6VT61|ensemblfungi:YDR434W intact:EBI-24869|uniprotkb:D3DLD6|ensemblfungi:YHR188C psi-mi:gpi17_yeast(display_long)|uniprotkb:GPI17(gene name)|psi-mi:GPI17(display_short)|uniprotkb:D9461.20(orf name)|uniprotkb:YDR434W(locus name) psi-mi:gpi16_yeast(display_long)|uniprotkb:GPI16(gene name)|psi-mi:GPI16(display_short)|uniprotkb:YHR188C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342619|imex:IM-14275-2608 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002842|interpro:IPR019540|refseq:NP_010722.3|mint:Q04080|ensemblfungi:YDR434W(gene)|ensemblfungi:YDR434W_mRNA(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex) refseq:NP_012058.1|sgd:S000001231|mint:P38875|dip:DIP-1888N|ensemblfungi:YHR188C(gene)|ensemblfungi:YHR188C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component) psi-mi:"MI:0469"(intact) - crc64:E9613CE0EA99F963 figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:7bBqUoVPfAOj/Pm4RPbzshzWNr0559292 rogid:qvK2gNcnfXW5KU81xOCtdz54jgI559292 intact-crc:1317625AF02EFA53|rigid:2zE6+yXeJZ+nLXgIARt7Ak5NiEI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39012 uniprotkb:Q04080 intact:EBI-7252|uniprotkb:D6VY88|ensemblfungi:YLR088W intact:EBI-7777|uniprotkb:D6VT61|ensemblfungi:YDR434W psi-mi:gaa1_yeast(display_long)|uniprotkb:GAA1(gene name)|psi-mi:GAA1(display_short)|uniprotkb:END2(gene name synonym)|uniprotkb:YLR088W(locus name)|uniprotkb:L9449.4(orf name) psi-mi:gpi17_yeast(display_long)|uniprotkb:GPI17(gene name)|psi-mi:GPI17(display_short)|uniprotkb:D9461.20(orf name)|uniprotkb:YDR434W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342630|imex:IM-14275-2609 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013189.1|sgd:S000004078|mint:P39012|dip:DIP-4824N|ensemblfungi:YLR088W(gene)|ensemblfungi:YLR088W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR007246(Gaa1-like, GPI transamidase component) sgd:S000002842|interpro:IPR019540|refseq:NP_010722.3|mint:Q04080|ensemblfungi:YDR434W(gene)|ensemblfungi:YDR434W_mRNA(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:amv3rxKpKmjGpnjzMInYFQXvlUg559292 rogid:7bBqUoVPfAOj/Pm4RPbzshzWNr0559292 intact-crc:3DD7E494D9E8C9BD|rigid:fPlvN4AO3uuMITE1bx1812uNDtA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04080 uniprotkb:P49018 intact:EBI-7777|uniprotkb:D6VT61|ensemblfungi:YDR434W intact:EBI-7822|uniprotkb:D6VSW3|ensemblfungi:YDR331W psi-mi:gpi17_yeast(display_long)|uniprotkb:GPI17(gene name)|psi-mi:GPI17(display_short)|uniprotkb:D9461.20(orf name)|uniprotkb:YDR434W(locus name) psi-mi:gpi8_yeast(display_long)|uniprotkb:GPI8(gene name)|psi-mi:GPI8(display_short)|uniprotkb:D9798.2(orf name)|uniprotkb:YDR331W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342641|imex:IM-14275-2610 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002842|interpro:IPR019540|refseq:NP_010722.3|mint:Q04080|ensemblfungi:YDR434W(gene)|ensemblfungi:YDR434W_mRNA(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex) refseq:NP_010618.1|sgd:S000002739|dip:DIP-5371N|mint:P49018|ensemblfungi:YDR331W(gene)|ensemblfungi:YDR331W_mRNA(transcript)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:7bBqUoVPfAOj/Pm4RPbzshzWNr0559292 rogid:5h/ZRVpqdt/EC4pSAd0qlKcUZUk559292 intact-crc:19E16EE46FD73B36|rigid:n/MZqQkDj5tDIsvxkTGqsnWkg98 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47131 uniprotkb:Q04120 intact:EBI-25560|uniprotkb:D6VWQ4|ensemblfungi:YJR085C intact:EBI-19631|uniprotkb:D6VT78|ensemblfungi:YDR453C psi-mi:yj55_yeast(display_long)|uniprotkb:J1863(orf name)|uniprotkb:YJR085C(locus name) psi-mi:tsa2_yeast(display_long)|uniprotkb:TSA2(gene name)|psi-mi:TSA2(display_short)|uniprotkb:Cytoplasmic thiol peroxidase 2(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein 2(gene name synonym)|uniprotkb:Thioredoxin peroxidase type Ib(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin TSA2(gene name synonym)|uniprotkb:D9461.38(orf name)|uniprotkb:YDR453C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342652|imex:IM-14275-2611 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003845|interpro:IPR005349(Protein of unknown function UPF0136, Transmembrane)|refseq:NP_012618.3|mint:P47131|ensemblfungi:YJR085C(gene)|ensemblfungi:YJR085C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR044890 refseq:NP_010741.1|sgd:S000002861|ensemblfungi:YDR453C(gene)|ensemblfungi:YDR453C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|rcsb pdb:5DVB|rcsb pdb:6UTL|reactome:R-SCE-5628897|rcsb pdb:5EPT|dip:DIP-4317N|mint:Q04120 psi-mi:"MI:0469"(intact) - crc64:43CC57C92081D745 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:LiWa//sQIDTRpDXKkbtQd1SIJeM559292 rogid:EAvk8fI2JOPylqetDAzROxC+7hQ559292 intact-crc:D42EF27D465E7EF3|rigid:FFCIAG7QeV7uNO0JN+l6EBU4MtY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38882 uniprotkb:Q04177 intact:EBI-24892|uniprotkb:D3DLE4|ensemblfungi:YHR196W intact:EBI-35844|uniprotkb:D6VT31|ensemblfungi:YDR398W psi-mi:utp9_yeast(display_long)|uniprotkb:t-UTP9(gene name synonym)|uniprotkb:UTP9(gene name)|psi-mi:UTP9(display_short)|uniprotkb:U three protein 9(gene name synonym)|uniprotkb:U3 protein 9 required for transcription(gene name synonym)|uniprotkb:YHR196W(locus name) psi-mi:utp5_yeast(display_long)|uniprotkb:U three protein 5(gene name synonym)|uniprotkb:U3 protein 5 required for transcription(gene name synonym)|uniprotkb:D9509.17(orf name)|uniprotkb:YDR398W(locus name)|uniprotkb:UTP5(gene name)|psi-mi:UTP5(display_short)|uniprotkb:t-UTP5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342663|imex:IM-14275-2612 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012066.1|sgd:S000001239|mint:P38882|dip:DIP-6634N|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|ensemblfungi:YHR196W(gene)|ensemblfungi:YHR196W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034455"(t-UTP complex)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4 refseq:NP_010686.1|sgd:S000002806|mint:Q04177|dip:DIP-1317N|ensemblfungi:YDR398W(gene)|ensemblfungi:YDR398W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034455"(t-UTP complex)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|rcsb pdb:6LQS psi-mi:"MI:0469"(intact) crc64:0C482C6A32855FF1 crc64:7A6F60C7C6F46C2A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cjrwDuKyMEgU0Zgn28yzNi6haV4559292 rogid:cpoFrHdK29TtGOfAINI5ceEgO3U559292 intact-crc:7E21F806C9A642A5|rigid:7gaBKfV0DUFvTicRDFddU4LUct4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04177 uniprotkb:P40470 intact:EBI-35844|uniprotkb:D6VT31|ensemblfungi:YDR398W intact:EBI-2084979|uniprotkb:D6VVG0|ensemblfungi:YIL127C psi-mi:utp5_yeast(display_long)|uniprotkb:U three protein 5(gene name synonym)|uniprotkb:U3 protein 5 required for transcription(gene name synonym)|uniprotkb:D9509.17(orf name)|uniprotkb:YDR398W(locus name)|uniprotkb:UTP5(gene name)|psi-mi:UTP5(display_short)|uniprotkb:t-UTP5(gene name synonym) psi-mi:rrt14_yeast(display_long)|uniprotkb:YIL127C(locus name)|uniprotkb:RRT14(gene name)|psi-mi:RRT14(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342674|imex:IM-14275-2613 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010686.1|sgd:S000002806|mint:Q04177|dip:DIP-1317N|ensemblfungi:YDR398W(gene)|ensemblfungi:YDR398W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034455"(t-UTP complex)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|rcsb pdb:6LQS sgd:S000001389|refseq:NP_012139.1|interpro:IPR031404|mint:P40470|ensemblfungi:YIL127C(gene)|ensemblfungi:YIL127C_mRNA(transcript)|go:"GO:0005730"(nucleolus)|rcsb pdb:5WLC|rcsb pdb:6LQP|rcsb pdb:6LQS|rcsb pdb:6LQU|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:7AJT psi-mi:"MI:0469"(intact) crc64:7A6F60C7C6F46C2A - figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cpoFrHdK29TtGOfAINI5ceEgO3U559292 rogid:Jv1tHpy0kCIv7gE6JY8kpmHm3UY559292 intact-crc:A602C4EBAEBBE9F4|rigid:2wgKjtyg62/dSJHJuIzZcynJDpE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04177 uniprotkb:P42945 intact:EBI-35844|uniprotkb:D6VT31|ensemblfungi:YDR398W intact:EBI-1884|uniprotkb:D6VW75|ensemblfungi:YJL109C psi-mi:utp5_yeast(display_long)|uniprotkb:U three protein 5(gene name synonym)|uniprotkb:U3 protein 5 required for transcription(gene name synonym)|uniprotkb:D9509.17(orf name)|uniprotkb:YDR398W(locus name)|uniprotkb:UTP5(gene name)|psi-mi:UTP5(display_short)|uniprotkb:t-UTP5(gene name synonym) psi-mi:utp10_yeast(display_long)|uniprotkb:UTP10(gene name)|psi-mi:UTP10(display_short)|uniprotkb:t-UTP10(gene name synonym)|uniprotkb:U three protein 10(gene name synonym)|uniprotkb:U3 protein 10 required for transcription(gene name synonym)|uniprotkb:J0808(orf name)|uniprotkb:YJL109C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342685|imex:IM-14275-2614 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010686.1|sgd:S000002806|mint:Q04177|dip:DIP-1317N|ensemblfungi:YDR398W(gene)|ensemblfungi:YDR398W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034455"(t-UTP complex)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|rcsb pdb:6LQS refseq:NP_012426.1|sgd:S000003645|dip:DIP-6466N|mint:P42945|ensemblfungi:YJL109C(gene)|ensemblfungi:YJL109C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034455"(t-UTP complex)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012954(BP28, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR022125|interpro:IPR040191|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:7A6F60C7C6F46C2A crc64:064480D1D249B241 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cpoFrHdK29TtGOfAINI5ceEgO3U559292 rogid:c7sxmixQnRLFmjuUMDkqZ260ebg559292 intact-crc:AB79C45FEBD0303F|rigid:9xrA+DSOKT21c23ynPVAmyyEXm8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53276 uniprotkb:Q04177 intact:EBI-23301|uniprotkb:D6VUR0|ensemblfungi:YGR128C intact:EBI-35844|uniprotkb:D6VT31|ensemblfungi:YDR398W psi-mi:utp8_yeast(display_long)|uniprotkb:UTP8(gene name)|psi-mi:UTP8(display_short)|uniprotkb:t-UTP8(gene name synonym)|uniprotkb:U three protein 8(gene name synonym)|uniprotkb:U3 protein 8 required for transcription(gene name synonym)|uniprotkb:YGR128C(locus name) psi-mi:utp5_yeast(display_long)|uniprotkb:U three protein 5(gene name synonym)|uniprotkb:U3 protein 5 required for transcription(gene name synonym)|uniprotkb:D9509.17(orf name)|uniprotkb:YDR398W(locus name)|uniprotkb:UTP5(gene name)|psi-mi:UTP5(display_short)|uniprotkb:t-UTP5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342696|imex:IM-14275-2615 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003360|refseq:NP_011644.3|dip:DIP-6747N|mint:P53276|ensemblfungi:YGR128C(gene)|ensemblfungi:YGR128C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005730"(nucleolus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034455"(t-UTP complex)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR018843|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU refseq:NP_010686.1|sgd:S000002806|mint:Q04177|dip:DIP-1317N|ensemblfungi:YDR398W(gene)|ensemblfungi:YDR398W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034455"(t-UTP complex)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|rcsb pdb:6LQS psi-mi:"MI:0469"(intact) crc64:6F5AE1492F841F49 crc64:7A6F60C7C6F46C2A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dG2UtBMuPQujwdovAL/FDjpqps0559292 rogid:cpoFrHdK29TtGOfAINI5ceEgO3U559292 intact-crc:FFD37EDC40B53AAE|rigid:0j/3hCuxKGW4YCeNfxcgt+nBaVk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04177 uniprotkb:Q04305 intact:EBI-35844|uniprotkb:D6VT31|ensemblfungi:YDR398W intact:EBI-28183|uniprotkb:D6VZR6|ensemblfungi:YMR093W psi-mi:utp5_yeast(display_long)|uniprotkb:U three protein 5(gene name synonym)|uniprotkb:U3 protein 5 required for transcription(gene name synonym)|uniprotkb:D9509.17(orf name)|uniprotkb:YDR398W(locus name)|uniprotkb:UTP5(gene name)|psi-mi:UTP5(display_short)|uniprotkb:t-UTP5(gene name synonym) psi-mi:utp15_yeast(display_long)|uniprotkb:U three protein 15(gene name synonym)|uniprotkb:U3 protein 15 required for transcription(gene name synonym)|uniprotkb:YM9582.18(orf name)|uniprotkb:YMR093W(locus name)|uniprotkb:UTP15(gene name)|psi-mi:UTP15(display_short)|uniprotkb:t-UTP15(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342707|imex:IM-14275-2616 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010686.1|sgd:S000002806|mint:Q04177|dip:DIP-1317N|ensemblfungi:YDR398W(gene)|ensemblfungi:YDR398W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034455"(t-UTP complex)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|rcsb pdb:6LQS refseq:NP_013811.1|sgd:S000004699|dip:DIP-1962N|mint:Q04305|ensemblfungi:YMR093W(gene)|ensemblfungi:YMR093W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034455"(t-UTP complex)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018983|interpro:IPR019775|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:7A6F60C7C6F46C2A crc64:2B74BA8BD496C8DA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cpoFrHdK29TtGOfAINI5ceEgO3U559292 rogid:4DswftRHSsPlKxMEIH1VnCc98r8559292 intact-crc:3DE0956446907416|rigid:4zZI81niKTuzRLCEFC6a0xGnVZ8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04177 uniprotkb:Q06679 intact:EBI-35844|uniprotkb:D6VT31|ensemblfungi:YDR398W intact:EBI-35712|uniprotkb:D6VSV7|ensemblfungi:YDR324C psi-mi:utp5_yeast(display_long)|uniprotkb:U three protein 5(gene name synonym)|uniprotkb:U3 protein 5 required for transcription(gene name synonym)|uniprotkb:D9509.17(orf name)|uniprotkb:YDR398W(locus name)|uniprotkb:UTP5(gene name)|psi-mi:UTP5(display_short)|uniprotkb:t-UTP5(gene name synonym) psi-mi:utp4_yeast(display_long)|uniprotkb:UTP4(gene name)|psi-mi:UTP4(display_short)|uniprotkb:t-UTP4(gene name synonym)|uniprotkb:U three protein 4(gene name synonym)|uniprotkb:U3 protein 4 required for transcription(gene name synonym)|uniprotkb:YDR324C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342718|imex:IM-14275-2617 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010686.1|sgd:S000002806|mint:Q04177|dip:DIP-1317N|ensemblfungi:YDR398W(gene)|ensemblfungi:YDR398W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034455"(t-UTP complex)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|rcsb pdb:6LQS refseq:NP_010611.3|sgd:S000002732|mint:Q06679|dip:DIP-6436N|ensemblfungi:YDR324C(gene)|ensemblfungi:YDR324C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:7A6F60C7C6F46C2A crc64:5D1C77899CABB40B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cpoFrHdK29TtGOfAINI5ceEgO3U559292 rogid:kAD4RO628jpcbjUoQXQbjcGVY88559292 intact-crc:25384C1E59B2CC17|rigid:51RlOVAuK+DLAjVB6S4devLuRPQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47155 uniprotkb:Q04201 intact:EBI-2051644|uniprotkb:D6VWT7|ensemblfungi:YJR118C intact:EBI-27928|uniprotkb:D6W0I3|ensemblfungi:YML101C psi-mi:ilm1_yeast(display_long)|uniprotkb:Increased loss of mitochondrial DNA protein 1(gene name synonym)|uniprotkb:J2033(orf name)|uniprotkb:ILM1(gene name)|psi-mi:ILM1(display_short)|uniprotkb:YJR118C(locus name) psi-mi:cue4_yeast(display_long)|uniprotkb:YML101C(locus name)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 4(gene name synonym)|uniprotkb:CUE4(gene name)|psi-mi:CUE4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342729|imex:IM-14275-2618 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003879|interpro:IPR018815|refseq:NP_012652.3|mint:P47155|ensemblfungi:YJR118C(gene)|ensemblfungi:YJR118C_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane) refseq:NP_013607.1|sgd:S000004568|dip:DIP-4525N|mint:Q04201|ensemblfungi:YML101C(gene)|ensemblfungi:YML101C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BrQhbXGvUjNG6Bt5c0J7T8qzMeI559292 rogid:NMBJHZbX4/gU01fk4evPDXm/M6w559292 intact-crc:FF9D6B94DCE2D25E|rigid:sXNt0o1mKPjrW45LOIb1HxjZg08 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:Q04228 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-27730|uniprotkb:D6VZG1|ensemblfungi:YML013W psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:ubx2_yeast(display_long)|uniprotkb:SEL1(gene name synonym)|uniprotkb:YM9571.05(orf name)|uniprotkb:YML013W(locus name)|uniprotkb:UBX2(gene name)|psi-mi:UBX2(display_short)|uniprotkb:Secretion lowering protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342740|imex:IM-14275-2619 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD refseq:NP_013699.1|sgd:S000004475|dip:DIP-5073N|mint:Q04228|ensemblfungi:YML013W(gene)|ensemblfungi:YML013W_mRNA(transcript)|go:"GO:0000837"(Doa10p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001012(UBX) psi-mi:"MI:0469"(intact) crc64:DBA26AF5B769C02A crc64:DA4DDD3D624C17B8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:pHZ9MnjC5Y3aC5hV43Z4fmkqI8w559292 intact-crc:F9C4BD5361DC422B|rigid:irQo9Vz1/RvxdcBY4S0dRJWilac false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04228 uniprotkb:P53044 intact:EBI-27730|uniprotkb:D6VZG1|ensemblfungi:YML013W intact:EBI-19997|uniprotkb:D6VUI5|uniprotkb:Q45U36|ensemblfungi:YGR048W psi-mi:ubx2_yeast(display_long)|uniprotkb:SEL1(gene name synonym)|uniprotkb:YM9571.05(orf name)|uniprotkb:YML013W(locus name)|uniprotkb:UBX2(gene name)|psi-mi:UBX2(display_short)|uniprotkb:Secretion lowering protein 1(gene name synonym) psi-mi:ufd1_yeast(display_long)|uniprotkb:UFD1(gene name)|psi-mi:UFD1(display_short)|uniprotkb:PIP3(gene name synonym)|uniprotkb:Polymerase-interacting protein 3(gene name synonym)|uniprotkb:YGR048W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342751|imex:IM-14275-2620 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013699.1|sgd:S000004475|dip:DIP-5073N|mint:Q04228|ensemblfungi:YML013W(gene)|ensemblfungi:YML013W_mRNA(transcript)|go:"GO:0000837"(Doa10p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001012(UBX) refseq:NP_011562.1|sgd:S000003280|go:"GO:0006274"(DNA replication termination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030894"(replisome)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1990112"(RQC complex)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|interpro:IPR004854(Ubiquitin fusion degradation protein UFD1)|interpro:IPR042299|rcsb pdb:1ZC1|rcsb pdb:6JWJ|reactome:R-SCE-110320|ensemblfungi:YGR048W(gene)|ensemblfungi:YGR048W_mRNA(transcript)|go:"GO:0000837"(Doa10p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|dip:DIP-1476N|mint:P53044 psi-mi:"MI:0469"(intact) crc64:DA4DDD3D624C17B8 crc64:198E0CD48B863B98 figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pHZ9MnjC5Y3aC5hV43Z4fmkqI8w559292 rogid:u/YG6aRuJ38NLsxGkUsfM9nXAnU559292 intact-crc:B79B6C5A4A1FD843|rigid:xn+G/dqSR0utaDf1TDQ/Uv3ywWA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04228 uniprotkb:Q04228 intact:EBI-27730|uniprotkb:D6VZG1|ensemblfungi:YML013W intact:EBI-27730|uniprotkb:D6VZG1|ensemblfungi:YML013W psi-mi:ubx2_yeast(display_long)|uniprotkb:SEL1(gene name synonym)|uniprotkb:YM9571.05(orf name)|uniprotkb:YML013W(locus name)|uniprotkb:UBX2(gene name)|psi-mi:UBX2(display_short)|uniprotkb:Secretion lowering protein 1(gene name synonym) psi-mi:ubx2_yeast(display_long)|uniprotkb:SEL1(gene name synonym)|uniprotkb:YM9571.05(orf name)|uniprotkb:YML013W(locus name)|uniprotkb:UBX2(gene name)|psi-mi:UBX2(display_short)|uniprotkb:Secretion lowering protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342762|imex:IM-14275-2621 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013699.1|sgd:S000004475|dip:DIP-5073N|mint:Q04228|ensemblfungi:YML013W(gene)|ensemblfungi:YML013W_mRNA(transcript)|go:"GO:0000837"(Doa10p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001012(UBX) refseq:NP_013699.1|sgd:S000004475|dip:DIP-5073N|mint:Q04228|ensemblfungi:YML013W(gene)|ensemblfungi:YML013W_mRNA(transcript)|go:"GO:0000837"(Doa10p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001012(UBX) psi-mi:"MI:0469"(intact) crc64:DA4DDD3D624C17B8 crc64:DA4DDD3D624C17B8 figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pHZ9MnjC5Y3aC5hV43Z4fmkqI8w559292 rogid:pHZ9MnjC5Y3aC5hV43Z4fmkqI8w559292 intact-crc:F243561E539F3F53|rigid:+Y9hdbTgduYFv6MZC6YHjSkrdcM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12168 uniprotkb:Q04228 intact:EBI-32973|uniprotkb:Q07268|uniprotkb:D6VYD8|ensemblfungi:YLR144C intact:EBI-27730|uniprotkb:D6VZG1|ensemblfungi:YML013W psi-mi:eng2_yeast(display_long)|uniprotkb:ACF2(gene name)|psi-mi:ACF2(display_short)|uniprotkb:YLR144C(locus name)|uniprotkb:Laminarinase-2(gene name synonym)|uniprotkb:ENG2(gene name synonym)|uniprotkb:PCA1(gene name synonym)|uniprotkb:L3180(orf name) psi-mi:ubx2_yeast(display_long)|uniprotkb:SEL1(gene name synonym)|uniprotkb:YM9571.05(orf name)|uniprotkb:YML013W(locus name)|uniprotkb:UBX2(gene name)|psi-mi:UBX2(display_short)|uniprotkb:Secretion lowering protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342773|imex:IM-14275-2622 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013245.1|sgd:S000004134|mint:Q12168|dip:DIP-2889N|ensemblfungi:YLR144C(gene)|ensemblfungi:YLR144C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042973"(glucan endo-1,3-beta-D-glucosidase activity)|go:"GO:0052861"(glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group)|go:"GO:0052862"(glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group)|interpro:IPR005200(Glycoside hydrolase, family 81)|interpro:IPR040451|interpro:IPR040720 refseq:NP_013699.1|sgd:S000004475|dip:DIP-5073N|mint:Q04228|ensemblfungi:YML013W(gene)|ensemblfungi:YML013W_mRNA(transcript)|go:"GO:0000837"(Doa10p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001012(UBX) psi-mi:"MI:0469"(intact) - crc64:DA4DDD3D624C17B8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8STCUe6Ie2CnTTBMjY8wrld5h44559292 rogid:pHZ9MnjC5Y3aC5hV43Z4fmkqI8w559292 intact-crc:16AE39091FE15FCC|rigid:Oq2f71/q7dnOCh8SP6U5lQVHXFM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38882 uniprotkb:Q04305 intact:EBI-24892|uniprotkb:D3DLE4|ensemblfungi:YHR196W intact:EBI-28183|uniprotkb:D6VZR6|ensemblfungi:YMR093W psi-mi:utp9_yeast(display_long)|uniprotkb:t-UTP9(gene name synonym)|uniprotkb:UTP9(gene name)|psi-mi:UTP9(display_short)|uniprotkb:U three protein 9(gene name synonym)|uniprotkb:U3 protein 9 required for transcription(gene name synonym)|uniprotkb:YHR196W(locus name) psi-mi:utp15_yeast(display_long)|uniprotkb:U three protein 15(gene name synonym)|uniprotkb:U3 protein 15 required for transcription(gene name synonym)|uniprotkb:YM9582.18(orf name)|uniprotkb:YMR093W(locus name)|uniprotkb:UTP15(gene name)|psi-mi:UTP15(display_short)|uniprotkb:t-UTP15(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342784|imex:IM-14275-2623 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012066.1|sgd:S000001239|mint:P38882|dip:DIP-6634N|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|ensemblfungi:YHR196W(gene)|ensemblfungi:YHR196W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034455"(t-UTP complex)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4 refseq:NP_013811.1|sgd:S000004699|dip:DIP-1962N|mint:Q04305|ensemblfungi:YMR093W(gene)|ensemblfungi:YMR093W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034455"(t-UTP complex)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018983|interpro:IPR019775|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:0C482C6A32855FF1 crc64:2B74BA8BD496C8DA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cjrwDuKyMEgU0Zgn28yzNi6haV4559292 rogid:4DswftRHSsPlKxMEIH1VnCc98r8559292 intact-crc:E96F7E0966FB787F|rigid:S5uftkjH4WfzKdzmMCcWe8UnZo8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53276 uniprotkb:Q04305 intact:EBI-23301|uniprotkb:D6VUR0|ensemblfungi:YGR128C intact:EBI-28183|uniprotkb:D6VZR6|ensemblfungi:YMR093W psi-mi:utp8_yeast(display_long)|uniprotkb:UTP8(gene name)|psi-mi:UTP8(display_short)|uniprotkb:t-UTP8(gene name synonym)|uniprotkb:U three protein 8(gene name synonym)|uniprotkb:U3 protein 8 required for transcription(gene name synonym)|uniprotkb:YGR128C(locus name) psi-mi:utp15_yeast(display_long)|uniprotkb:U three protein 15(gene name synonym)|uniprotkb:U3 protein 15 required for transcription(gene name synonym)|uniprotkb:YM9582.18(orf name)|uniprotkb:YMR093W(locus name)|uniprotkb:UTP15(gene name)|psi-mi:UTP15(display_short)|uniprotkb:t-UTP15(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342795|imex:IM-14275-2624 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003360|refseq:NP_011644.3|dip:DIP-6747N|mint:P53276|ensemblfungi:YGR128C(gene)|ensemblfungi:YGR128C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005730"(nucleolus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034455"(t-UTP complex)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR018843|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU refseq:NP_013811.1|sgd:S000004699|dip:DIP-1962N|mint:Q04305|ensemblfungi:YMR093W(gene)|ensemblfungi:YMR093W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034455"(t-UTP complex)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018983|interpro:IPR019775|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:6F5AE1492F841F49 crc64:2B74BA8BD496C8DA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:dG2UtBMuPQujwdovAL/FDjpqps0559292 rogid:4DswftRHSsPlKxMEIH1VnCc98r8559292 intact-crc:689DF8D3EFE80074|rigid:476Y4hMPsXrZCUY0/CehTXJ8mv8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04322 uniprotkb:P53751 intact:EBI-27427|uniprotkb:D6W016|ensemblfungi:YMR192W intact:EBI-28557|uniprotkb:D6W1P0|ensemblfungi:YNR065C psi-mi:gyl1_yeast(display_long)|uniprotkb:YMR192W(locus name)|uniprotkb:YM9646.04(orf name)|uniprotkb:GYL1(gene name)|psi-mi:GYL1(display_short)|uniprotkb:APP2(gene name synonym)|uniprotkb:GYP5-like protein 1(gene name synonym) psi-mi:yn94_yeast(display_long)|uniprotkb:N3539(orf name)|uniprotkb:YNR065C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342806|imex:IM-14275-2625 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q04322|refseq:NP_013917.1|sgd:S000004804|dip:DIP-2891N|ensemblfungi:YMR192W(gene)|ensemblfungi:YMR192W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0017157"(regulation of exocytosis)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969 refseq:NP_014463.1|sgd:S000005348|dip:DIP-4251N|mint:P53751|ensemblfungi:YNR065C(gene)|ensemblfungi:YNR065C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778 psi-mi:"MI:0469"(intact) - crc64:C0361878FE4DAB90 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:JXXEUKwB+ysZExb+8We4yeNrftM559292 rogid:7iodiUQu3ZxDDC4KQlI3CoYD1IE559292 intact-crc:789D5E28616E0107|rigid:+1tEk4Kb3ExxzqILH2f3zV2/5W0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04344 uniprotkb:Q04344 intact:EBI-8416|uniprotkb:D6VRM5|ensemblfungi:YDL125C intact:EBI-8416|uniprotkb:D6VRM5|ensemblfungi:YDL125C psi-mi:hnt1_yeast(display_long)|uniprotkb:HNT1(gene name)|psi-mi:HNT1(display_short)|uniprotkb:HIT1(gene name synonym)|uniprotkb:Histidine triad nucleotide-binding protein HNT1(gene name synonym)|uniprotkb:Hit family protein 1(gene name synonym)|uniprotkb:YDL125C(locus name) psi-mi:hnt1_yeast(display_long)|uniprotkb:HNT1(gene name)|psi-mi:HNT1(display_short)|uniprotkb:HIT1(gene name synonym)|uniprotkb:Histidine triad nucleotide-binding protein HNT1(gene name synonym)|uniprotkb:Hit family protein 1(gene name synonym)|uniprotkb:YDL125C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342817|imex:IM-14275-2626 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010158.1|sgd:S000002283|dip:DIP-2760N|mint:Q04344|ensemblfungi:YDL125C(gene)|ensemblfungi:YDL125C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0010043"(response to zinc ion)|go:"GO:0043530"(adenosine 5'-monophosphoramidase activity)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR001310("Histidine triad (HIT) protein")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|interpro:IPR039384 refseq:NP_010158.1|sgd:S000002283|dip:DIP-2760N|mint:Q04344|ensemblfungi:YDL125C(gene)|ensemblfungi:YDL125C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0010043"(response to zinc ion)|go:"GO:0043530"(adenosine 5'-monophosphoramidase activity)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR001310("Histidine triad (HIT) protein")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|interpro:IPR039384 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:93se/ObwboPzYXLyIpTm7RrKhl0559292 rogid:93se/ObwboPzYXLyIpTm7RrKhl0559292 intact-crc:485AB86331B7A3A6|rigid:Xk4yQSO9F18mB5wPI3oi0WWHiTk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12462 uniprotkb:Q04370 intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C intact:EBI-2077297|uniprotkb:D6VZK0|uniprotkb:Q6B1L4|ensemblfungi:YMR026C psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:pex12_yeast(display_long)|uniprotkb:PEX12(gene name)|psi-mi:PEX12(display_short)|uniprotkb:Peroxin-12(gene name synonym)|uniprotkb:YM9711.16C(orf name)|uniprotkb:YMR026C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342828|imex:IM-14275-2627 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) refseq:NP_013739.1|sgd:S000004628|dip:DIP-7940N|mint:Q04370|ensemblfungi:YMR026C(gene)|ensemblfungi:YMR026C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR006845(Pex, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017375(Peroxisome assembly, p12)|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-9603798 psi-mi:"MI:0469"(intact) - crc64:98E6300C2CBFA16A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 rogid:6NMDWbnAfeyEYrN7lao6UTtVsro559292 intact-crc:E20A360CA1954377|rigid:2EhVEvrFmBdn5+XNiOAOwHqy3uU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:Q04383 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342839|imex:IM-14275-2628 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 intact-crc:D9E95DBD7EB17068|rigid:IcxO2MQdsmok4X4jw0/x6EYnOIQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:Q04383 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342850|imex:IM-14275-2629 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) psi-mi:"MI:0469"(intact) crc64:DBA26AF5B769C02A - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 intact-crc:73D41CFE56203DCB|rigid:b1l0gKV01WXKmyGPQL5plqFofbQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04383 uniprotkb:P19807 intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342861|imex:IM-14275-2630 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:3E899E2D24992E4B|rigid:hXPRq72rx3NNOUky9cRW2PVlk4U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04383 uniprotkb:P24276 intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W intact:EBI-18153|uniprotkb:D6VSS2|ensemblfungi:YDR293C psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:ssd1_yeast(display_long)|uniprotkb:SSD1(gene name)|psi-mi:SSD1(display_short)|uniprotkb:CLA1(gene name synonym)|uniprotkb:RLD1(gene name synonym)|uniprotkb:SRK1(gene name synonym)|uniprotkb:YDR293C(locus name)|uniprotkb:D9819.4(orf name)|uniprotkb:Protein SRK1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342872|imex:IM-14275-2631 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) refseq:NP_010579.1|sgd:S000002701|ensemblfungi:YDR293C(gene)|ensemblfungi:YDR293C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051301"(cell division)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR041093|interpro:IPR041505|rcsb pdb:5NCL|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007049"(cell cycle)|dip:DIP-6449N|mint:P24276 psi-mi:"MI:0469"(intact) - crc64:3D50FD6838ECA514 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 rogid:myt8+lnu2/li6TuGiM5GBfMtUiw559292 intact-crc:DC3F7EF525FE7851|rigid:4l/d0QpHL3eseKwc8ixGqzxQujI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04383 uniprotkb:P26570 intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342883|imex:IM-14275-2632 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N psi-mi:"MI:0469"(intact) - crc64:8B7F009521F72C15 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 intact-crc:F94E872CAAF412CB|rigid:dYmOnonj4+utGa/UOVv+OC1z5+o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30605 uniprotkb:Q04383 intact:EBI-2050956|uniprotkb:D6VTB9|ensemblfungi:YDR497C intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W psi-mi:itr1_yeast(display_long)|uniprotkb:D9719.3(orf name)|uniprotkb:YDR497C(locus name)|uniprotkb:ITR1(gene name)|psi-mi:ITR1(display_short) psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342894|imex:IM-14275-2633 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010785.1|sgd:S000002905|dip:DIP-7406N|mint:P30605|ensemblfungi:YDR497C(gene)|ensemblfungi:YDR497C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GgtK4YFe7ZCZcmVpV5q1KY2F0Ds559292 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 intact-crc:40E0DD839DE45B49|rigid:B5qnbSFf39zzJ+y3WLtlTYD18Xk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04383 uniprotkb:P32465 intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342905|imex:IM-14275-2634 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 intact-crc:2586A55187D23D91|rigid:EkHbEJdPjYfyLQTX6Gn/2pK/AFY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04383 uniprotkb:P32568 intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342916|imex:IM-14275-2635 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 intact-crc:E66447022485BBB2|rigid:HEfUVp1SL1ma+8OsBMU+8ghUev0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:Q04383 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342927|imex:IM-14275-2636 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 intact-crc:F5AA8A7691977AD0|rigid:ts+0Mdk2D6+jLobeaaFoR2hRm6M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04383 uniprotkb:P35844 intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W intact:EBI-9648|ensemblfungi:YPL145C|uniprotkb:D6W3M4|uniprotkb:E9P8U8 psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:kes1_yeast(display_long)|uniprotkb:KES1(gene name)|psi-mi:KES1(display_short)|uniprotkb:OSH4(gene name synonym)|uniprotkb:Protein KES1(gene name synonym)|uniprotkb:LPI3C(orf name)|uniprotkb:P2614(orf name)|uniprotkb:YPL145C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342938|imex:IM-14275-2637 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) ensemblfungi:YPL145C(gene)|ensemblfungi:YPL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035621"(ER to Golgi ceramide transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|rcsb pdb:1ZHT|rcsb pdb:1ZHW|rcsb pdb:1ZHX|rcsb pdb:1ZHY|rcsb pdb:1ZHZ|rcsb pdb:1ZI7|rcsb pdb:3SPW|rcsb pdb:4F4B|rcsb pdb:4FES|rcsb pdb:4JCH|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_015180.1|sgd:S000006066|dip:DIP-2867N|mint:P35844 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 rogid:6vsHrA4RScGr2+xmii0wiuvK1OM559292 intact-crc:4779C162325657FB|rigid:XdsbsaeOI44z9wQUd1xuI9QWkXs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38623 uniprotkb:Q04383 intact:EBI-14885|uniprotkb:Q02532|uniprotkb:Q06557|uniprotkb:D6VYP6|ensemblfungi:YLR248W intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W psi-mi:rck2_yeast(display_long)|uniprotkb:RCK2(gene name)|psi-mi:RCK2(display_short)|uniprotkb:CLK1(gene name synonym)|uniprotkb:CMK3(gene name synonym)|uniprotkb:YLR248W(locus name)|uniprotkb:L9672.6(orf name)|uniprotkb:CAM kinase-like protein kinase CLK1(gene name synonym) psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342949|imex:IM-14275-2638 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013349.1|sgd:S000004238|ensemblfungi:YLR248W(gene)|ensemblfungi:YLR248W_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-9619229|dip:DIP-5079N|mint:P38623 refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) psi-mi:"MI:0469"(intact) crc64:00DDC674F6723E6A - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4VUkn/0mqnutY8hSJdNTA3ZyPeY559292 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 intact-crc:27D5A6901B8BDC1E|rigid:lcBMeuKbn0Vlg3jAeJ8trhvConM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39719 uniprotkb:Q04383 intact:EBI-20703|uniprotkb:Q05165|uniprotkb:D6VPG5|ensemblfungi:YAL053W intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W psi-mi:flc2_yeast(display_long)|uniprotkb:YAL053W(locus name)|uniprotkb:FLC2(gene name)|psi-mi:FLC2(display_short)|uniprotkb:FAD transporter 2(gene name synonym)|uniprotkb:TRP-like ion channel FLC2(gene name synonym) psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342960|imex:IM-14275-2639 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009348.2|sgd:S000000049|ensemblfungi:YAL053W(gene)|ensemblfungi:YAL053W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241|go:"GO:0055085"(transmembrane transport)|dip:DIP-6708N|mint:P39719 refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:NOmMW54DNa0o7vM945DlZgVUy44559292 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 intact-crc:1F644CCD86C71DE6|rigid:41idW+EuKBpww80ztbCHUEWJGZs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04383 uniprotkb:P40024 intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W intact:EBI-22498|uniprotkb:D3DLT5|ensemblfungi:YER036C psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:arb1_yeast(display_long)|uniprotkb:YER036C(locus name)|uniprotkb:ATP-binding cassette protein involved in ribosome biogenesis 1(gene name synonym)|uniprotkb:ARB1(gene name)|psi-mi:ARB1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342971|imex:IM-14275-2640 author score:99.32 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) refseq:NP_010953.1|sgd:S000000838|dip:DIP-4341N|mint:P40024|ensemblfungi:YER036C(gene)|ensemblfungi:YER036C_mRNA(transcript)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|rcsb pdb:6R84 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.32|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 rogid:wt/cIx02hhFgOW4Zl4T6s0ZX8l4559292 intact-crc:C77065CB0F4CBF31|rigid:NsvmgK3bnHCWsYA7CPIAdGtGEnM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40260 uniprotkb:Q04383 intact:EBI-10714|ensemblfungi:YGR121C|uniprotkb:D6VUQ2 intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W psi-mi:mep1_yeast(display_long)|uniprotkb:MEP1(gene name)|psi-mi:MEP1(display_short)|uniprotkb:YGR121C(locus name)|uniprotkb:G6331(orf name)|uniprotkb:AMT1(gene name synonym) psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342982|imex:IM-14275-2641 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR121C(gene)|ensemblfungi:YGR121C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|sgd:S000003353|refseq:NP_011636.3|mint:P40260|dip:DIP-5530N refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VnoBl5jhQD24N0SbCLv68HCwl1U559292 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 intact-crc:E3244669E85642AB|rigid:m4VXF6R6cMnDc4XC9b83003YzDw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04383 uniprotkb:P40474 intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W intact:EBI-25203|uniprotkb:D6VVG6|ensemblfungi:YIL121W psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:qdr2_yeast(display_long)|uniprotkb:YIL121W(locus name)|uniprotkb:QDR2(gene name)|psi-mi:QDR2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6342993|imex:IM-14275-2642 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) refseq:NP_012145.1|sgd:S000001383|mint:P40474|dip:DIP-5661N|ensemblfungi:YIL121W(gene)|ensemblfungi:YIL121W_mRNA(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060003"(copper ion export)|go:"GO:0071944"(cell periphery)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 rogid:5vIWIjaHjbqDqaeGri7sbxOt2XQ559292 intact-crc:FE2B831B1916D52E|rigid:N5oEyqRuVMSIrQXmeDCAUYkzyCI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41811 uniprotkb:Q04383 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343004|imex:IM-14275-2643 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) psi-mi:"MI:0469"(intact) crc64:6A5E50BBEB02CB58 - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 intact-crc:8958630C4A3123A2|rigid:fHEWCCiEnhgqDHZR4S2VSR91kAU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43621 uniprotkb:Q04383 intact:EBI-4876|uniprotkb:D6VTT4|ensemblfungi:YFR051C intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W psi-mi:copd_yeast(display_long)|uniprotkb:RET2(gene name)|psi-mi:RET2(display_short)|uniprotkb:YFR051C(locus name)|uniprotkb:Delta-coat protein(gene name synonym) psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343015|imex:IM-14275-2644 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001947|refseq:NP_116709.3|dip:DIP-5255N|mint:P43621|ensemblfungi:YFR051C(gene)|ensemblfungi:YFR051C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|rcsb pdb:5FJW|rcsb pdb:5FJX|rcsb pdb:5FJZ|rcsb pdb:5FK0|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) psi-mi:"MI:0469"(intact) crc64:AA730F046655EE5A - figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:auvjuT8ffm1R4P3mRKEIWAsynW0559292 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 intact-crc:621763CE47C8C4A9|rigid:EQRgHf5hk2P4yR3JO3KBSJzkejM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04383 uniprotkb:P50276 intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343026|imex:IM-14275-2645 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:75F53BFD02FE6ABB|rigid:3z/sHi1jJqMlclyaPJjKHL2gd7s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53049 uniprotkb:Q04383 intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343037|imex:IM-14275-2646 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 intact-crc:308BCDC4DEB09CF9|rigid:0QmYRjpgjpzy6cCgeaLrhr4giNE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53283 uniprotkb:Q04383 intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343048|imex:IM-14275-2647 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 intact-crc:01D90FE878983E3D|rigid:qUAypsaFwUFbH6JvXqm6D4epZTE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53388 uniprotkb:Q04383 intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343059|imex:IM-14275-2648 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) psi-mi:"MI:0469"(intact) crc64:488A382656039D0B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 intact-crc:C4366B605CFAE992|rigid:AM0JXPOCAyJQRwbfOO7jUC4++s8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04383 uniprotkb:P53390 intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343070|imex:IM-14275-2649 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N psi-mi:"MI:0469"(intact) - crc64:2309338F36D96258 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 intact-crc:A3576B45B38B521A|rigid:HuFPDRQZfelux11OHXYKLy0yA/o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04383 uniprotkb:P53832 intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W intact:EBI-2055941|uniprotkb:D6W0R1|ensemblfungi:YNL283C psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:wsc2_yeast(display_long)|uniprotkb:YNL283C(locus name)|uniprotkb:N0583(orf name)|uniprotkb:WSC2(gene name)|psi-mi:WSC2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343081|imex:IM-14275-2650 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) refseq:NP_014116.1|sgd:S000005227|interpro:IPR002889(Carbohydrate-binding WSC)|mint:P53832|ensemblfungi:YNL283C(gene)|ensemblfungi:YNL283C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 rogid:5wadvTv6SxcIAb60yfnuGMfa8pY559292 intact-crc:30D7C04CE5C1712A|rigid:y+M1GJNR8tOTmzbBbSR+gaEO3S8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02785 uniprotkb:Q04383 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343092|imex:IM-14275-2651 author score:99.32 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.32|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 intact-crc:B803DA4EF5DA2385|rigid:1sWLq0AJkwkSTxo1A15paYkUCwk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:Q04383 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343103|imex:IM-14275-2652 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 intact-crc:289D36E98A5F49A8|rigid:+uGfMRiQ/zEAK/uYOd7XRvNOUdk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04383 uniprotkb:Q03860 intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343114|imex:IM-14275-2653 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) - crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:374778E9831BDE41|rigid:8PohCpIuGu/9j4CBwJXGmOBQXPo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06689 uniprotkb:Q04383 intact:EBI-38659|uniprotkb:D6VZ50|ensemblfungi:YLR413W intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W psi-mi:yl413_yeast(display_long)|uniprotkb:YLR413W(locus name) psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343125|imex:IM-14275-2654 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013517.1|sgd:S000004405|mint:Q06689|dip:DIP-5075N|ensemblfungi:YLR413W(gene)|ensemblfungi:YLR413W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0071944"(cell periphery)|interpro:IPR009571(SUR7) refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) psi-mi:"MI:0469"(intact) crc64:92E23436DC857E95 - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AoTGKjLhw0NECrtuftZqLANonds559292 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 intact-crc:A7A90D7454E2188E|rigid:WBs16wVVqfXA2m7Vqi8NXZkJlqw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04383 uniprotkb:Q07824 intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343136|imex:IM-14275-2655 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 intact-crc:C5AFC0A56F5F52DE|rigid:VH7ssQMB2ec+grXCauYi4NWVilw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08967 uniprotkb:Q04383 intact:EBI-36673|uniprotkb:D6W3E9|ensemblfungi:YPL221W intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W psi-mi:flc1_yeast(display_long)|uniprotkb:FAD transporter 1(gene name synonym)|uniprotkb:FLC1(gene name)|psi-mi:FLC1(display_short)|uniprotkb:TRP-like ion channel protein FLC1(gene name synonym)|uniprotkb:Heme utilization factor 1(gene name synonym)|uniprotkb:Bypass of PAM1 protein 1(gene name synonym)|uniprotkb:HUF1(gene name synonym)|uniprotkb:YPL221W(locus name)|uniprotkb:BOP1(gene name synonym) psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343147|imex:IM-14275-2656 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015103.1|sgd:S000006142|mint:Q08967|dip:DIP-3965N|ensemblfungi:YPL221W(gene)|ensemblfungi:YPL221W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055085"(transmembrane transport)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241 refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:r6CcZGEjxHUk2w0iBUBvnAPaFd4559292 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 intact-crc:8C80D959759A8778|rigid:/iVRLV/m7z0zT0hH9eGn+BszfrE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12256 uniprotkb:Q04383 intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343158|imex:IM-14275-2657 author score:99.32 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.32|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 intact-crc:C8C572C29BADF232|rigid:cIFazk2yG+APzqF1Mac9ULjiDvQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3E772 uniprotkb:Q04383 intact:EBI-2070524|uniprotkb:D6VUV3|ensemblfungi:YGR169C-A intact:EBI-2079237|uniprotkb:D6VTC3|ensemblfungi:YDR501W psi-mi:lso2_yeast(display_long)|uniprotkb:LSO2(gene name)|psi-mi:LSO2(display_short)|uniprotkb:Late-annotated small open reading frame 2(gene name synonym)|uniprotkb:YGR169C-A(locus name) psi-mi:plm2_yeast(display_long)|uniprotkb:PLM2(gene name)|psi-mi:PLM2(display_short)|uniprotkb:Plasmid maintenance protein 2(gene name synonym)|uniprotkb:YDR501W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343169|imex:IM-14275-2658 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000028521|refseq:NP_878080.3|mint:Q3E772|ensemblfungi:YGR169C-A(gene)|ensemblfungi:YGR169C-A_mRNA(transcript)|go:"GO:0002182"(cytoplasmic translational elongation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0043022"(ribosome binding)|go:"GO:0055072"(iron ion homeostasis)|rcsb pdb:6Z6J|rcsb pdb:6Z6K refseq:NP_010789.1|sgd:S000002909|dip:DIP-8546N|mint:Q04383|ensemblfungi:YDR501W(gene)|ensemblfungi:YDR501W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rgtvxbeFiShVE//UX0Py5Rw3BmU559292 rogid:z8nheANMXGa+hrvHgvDcZ+2umu4559292 intact-crc:1F46668825B1DE6F|rigid:BaEIKkXddaSJ8O0oT4gb9tQgXVc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04396 uniprotkb:P25361 intact:EBI-35436|uniprotkb:D6VTC5|ensemblfungi:YDR503C intact:EBI-21909|uniprotkb:D6VR52|ensemblfungi:YCR043C psi-mi:lpp1_yeast(display_long)|uniprotkb:LPP1(gene name)|psi-mi:LPP1(display_short)|uniprotkb:YDR503C(locus name)|uniprotkb:D9719.9(orf name)|uniprotkb:Phosphatidate phosphatase(gene name synonym)|uniprotkb:Lysophosphatidate phosphatase(gene name synonym) psi-mi:yct3_yeast(display_long)|uniprotkb:YCR43C(orf name)|uniprotkb:YCR725(orf name)|uniprotkb:YCR043C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343180|imex:IM-14275-2659 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010791.3|sgd:S000002911|mint:Q04396|dip:DIP-1415N|ensemblfungi:YDR503C(gene)|ensemblfungi:YDR503C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000810"(diacylglycerol diphosphate phosphatase activity)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042577"(lipid phosphatase activity)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR043216|reactome:R-SCE-1660661|reactome:R-SCE-2029485|reactome:R-SCE-419408 sgd:S000000639|refseq:NP_009972.1|mint:P25361|ensemblfungi:YCR043C(gene)|ensemblfungi:YCR043C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0043332"(mating projection tip) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WSLmGL9DQuSCqyVf3vQjK753VsI559292 rogid:bEMtsAa5vCsWqGOiXwBK40Pa0xQ559292 intact-crc:774D6E3E872BA29A|rigid:Aa5PhRenTFCrw/brpYp7fGVUfJA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04396 uniprotkb:P40071 intact:EBI-35436|uniprotkb:D6VTC5|ensemblfungi:YDR503C intact:EBI-22657|uniprotkb:D3DM19|ensemblfungi:YER113C psi-mi:lpp1_yeast(display_long)|uniprotkb:LPP1(gene name)|psi-mi:LPP1(display_short)|uniprotkb:YDR503C(locus name)|uniprotkb:D9719.9(orf name)|uniprotkb:Phosphatidate phosphatase(gene name synonym)|uniprotkb:Lysophosphatidate phosphatase(gene name synonym) psi-mi:tmn3_yeast(display_long)|uniprotkb:YER113C(locus name)|uniprotkb:TMN3(gene name)|psi-mi:TMN3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343191|imex:IM-14275-2660 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010791.3|sgd:S000002911|mint:Q04396|dip:DIP-1415N|ensemblfungi:YDR503C(gene)|ensemblfungi:YDR503C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000810"(diacylglycerol diphosphate phosphatase activity)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042577"(lipid phosphatase activity)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR043216|reactome:R-SCE-1660661|reactome:R-SCE-2029485|reactome:R-SCE-419408 refseq:NP_011038.3|sgd:S000000915|dip:DIP-849N|mint:P40071|ensemblfungi:YER113C(gene)|ensemblfungi:YER113C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006811"(ion transport)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0072657"(protein localization to membrane)|interpro:IPR004240("Nonaspanin (TM9SF)") psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WSLmGL9DQuSCqyVf3vQjK753VsI559292 rogid:8BxN4sGvO60kSO6ApFWZmiaQjAI559292 intact-crc:E0949C18CDBB0ADB|rigid:x1GL30U99tfVhXYobtLDQUOLlak false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04396 uniprotkb:Q04396 intact:EBI-35436|uniprotkb:D6VTC5|ensemblfungi:YDR503C intact:EBI-35436|uniprotkb:D6VTC5|ensemblfungi:YDR503C psi-mi:lpp1_yeast(display_long)|uniprotkb:LPP1(gene name)|psi-mi:LPP1(display_short)|uniprotkb:YDR503C(locus name)|uniprotkb:D9719.9(orf name)|uniprotkb:Phosphatidate phosphatase(gene name synonym)|uniprotkb:Lysophosphatidate phosphatase(gene name synonym) psi-mi:lpp1_yeast(display_long)|uniprotkb:LPP1(gene name)|psi-mi:LPP1(display_short)|uniprotkb:YDR503C(locus name)|uniprotkb:D9719.9(orf name)|uniprotkb:Phosphatidate phosphatase(gene name synonym)|uniprotkb:Lysophosphatidate phosphatase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343202|imex:IM-14275-2661 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010791.3|sgd:S000002911|mint:Q04396|dip:DIP-1415N|ensemblfungi:YDR503C(gene)|ensemblfungi:YDR503C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000810"(diacylglycerol diphosphate phosphatase activity)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042577"(lipid phosphatase activity)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR043216|reactome:R-SCE-1660661|reactome:R-SCE-2029485|reactome:R-SCE-419408 refseq:NP_010791.3|sgd:S000002911|mint:Q04396|dip:DIP-1415N|ensemblfungi:YDR503C(gene)|ensemblfungi:YDR503C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000810"(diacylglycerol diphosphate phosphatase activity)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042577"(lipid phosphatase activity)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR043216|reactome:R-SCE-1660661|reactome:R-SCE-2029485|reactome:R-SCE-419408 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WSLmGL9DQuSCqyVf3vQjK753VsI559292 rogid:WSLmGL9DQuSCqyVf3vQjK753VsI559292 intact-crc:52193B58BC92FB65|rigid:E2aP0hjOJpEZPGuicS+YcRDMKOo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04396 uniprotkb:Q12270 intact:EBI-35436|uniprotkb:D6VTC5|ensemblfungi:YDR503C intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:lpp1_yeast(display_long)|uniprotkb:LPP1(gene name)|psi-mi:LPP1(display_short)|uniprotkb:YDR503C(locus name)|uniprotkb:D9719.9(orf name)|uniprotkb:Phosphatidate phosphatase(gene name synonym)|uniprotkb:Lysophosphatidate phosphatase(gene name synonym) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343213|imex:IM-14275-2662 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010791.3|sgd:S000002911|mint:Q04396|dip:DIP-1415N|ensemblfungi:YDR503C(gene)|ensemblfungi:YDR503C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000810"(diacylglycerol diphosphate phosphatase activity)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042577"(lipid phosphatase activity)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR043216|reactome:R-SCE-1660661|reactome:R-SCE-2029485|reactome:R-SCE-419408 refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WSLmGL9DQuSCqyVf3vQjK753VsI559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:618E58C647FD5FA6|rigid:jJvm2Fj2dORuTs5Dfu4a8Y/LKDk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23202 uniprotkb:Q04410 intact:EBI-20138|uniprotkb:D6W0W3|ensemblfungi:YNL229C intact:EBI-32083|uniprotkb:D6VTD8|ensemblfungi:YDR517W psi-mi:ure2_yeast(display_long)|uniprotkb:URE2(gene name)|psi-mi:URE2(display_short)|uniprotkb:Disulfide reductase(gene name synonym)|uniprotkb:Glutathione peroxidase(gene name synonym)|uniprotkb:N1165(orf name)|uniprotkb:YNL229C(locus name) psi-mi:grh1_yeast(display_long)|uniprotkb:GRH1(gene name)|psi-mi:GRH1(display_short)|uniprotkb:YDR517W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343224|imex:IM-14275-2663 author score:99.36 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014170.1|sgd:S000005173|ensemblfungi:YNL229C(gene)|ensemblfungi:YNL229C_mRNA(transcript)|mint:P23202|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0010044"(response to aluminum ion)|go:"GO:0032447"(protein urmylation)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR017298(Prion URE2)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:1G6W|rcsb pdb:1G6Y|rcsb pdb:1HQO|rcsb pdb:1JZR|rcsb pdb:1K0A|rcsb pdb:1K0B|rcsb pdb:1K0C|rcsb pdb:1K0D|go:"GO:0003714"(transcription corepressor activity)|dip:DIP-1308N refseq:NP_010805.1|sgd:S000002925|dip:DIP-6613N|mint:Q04410|ensemblfungi:YDR517W(gene)|ensemblfungi:YDR517W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0009306"(protein secretion)|go:"GO:0031090"(organelle membrane)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR007583(GRASP55/65)|interpro:IPR024958|interpro:IPR036034|rcsb pdb:6G8Y|reactome:R-SCE-162658|reactome:R-SCE-204005 psi-mi:"MI:0469"(intact) crc64:2C628976034B0F1C crc64:A7CE62DFE4631214 figure legend:tables S3 and S4|author-confidence:99.36|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jjsWygBsEp8axNurMa3pxPMQJ2k559292 rogid:Tj4Jf1BeT57ROzFoNoi+g9GLuYk559292 intact-crc:723AA20787CE273E|rigid:DdM9UbwTXhThtKNzM/1pGz8Kmx8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33204 uniprotkb:Q04439 intact:EBI-2757|uniprotkb:D6VXS3|ensemblfungi:YKL013C intact:EBI-11687|ensemblfungi:YMR109W|uniprotkb:D6VZT2 psi-mi:arpc4_yeast(display_long)|uniprotkb:ARC19(gene name)|psi-mi:ARC19(display_short)|uniprotkb:YKL013C(locus name)|uniprotkb:YKL166(orf name)|uniprotkb:Arp2/3 complex 20 kDa(gene name synonym) psi-mi:myo5_yeast(display_long)|uniprotkb:MYO5(gene name)|psi-mi:MYO5(display_short)|uniprotkb:YMR109W(locus name)|uniprotkb:YM9718.08(orf name)|uniprotkb:Class I unconventional myosin MYO5(gene name synonym)|uniprotkb:Type I myosin MYO5(gene name synonym)|uniprotkb:Actin-dependent myosin-I MYO5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343235|imex:IM-14275-2664 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012912.1|sgd:S000001496|dip:DIP-1819N|mint:P33204|ensemblfungi:YKL013C(gene)|ensemblfungi:YKL013C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 ensemblfungi:YMR109W_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0009651"(response to salt stress)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051286"(cell tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071944"(cell periphery)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035535|ensemblfungi:YMR109W(gene)|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|rcsb pdb:1YP5|rcsb pdb:1ZUY|refseq:NP_013827.1|sgd:S000004715|mint:Q04439|dip:DIP-2222N psi-mi:"MI:0469"(intact) crc64:B80CBD6642E39C1C crc64:DFFB9EC16B61CD29 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wscMsqBK/3Rsah+2vbE3REyYhhg559292 rogid:n/Po/L9Xd7LP+fY39QaqP/s5US4559292 intact-crc:1B4CDE222FC632F9|rigid:9sfzLgxlE7F3HH19Z9ZcQSfC48c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04439 uniprotkb:P36027 intact:EBI-11687|ensemblfungi:YMR109W|uniprotkb:D6VZT2 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:myo5_yeast(display_long)|uniprotkb:MYO5(gene name)|psi-mi:MYO5(display_short)|uniprotkb:YMR109W(locus name)|uniprotkb:YM9718.08(orf name)|uniprotkb:Class I unconventional myosin MYO5(gene name synonym)|uniprotkb:Type I myosin MYO5(gene name synonym)|uniprotkb:Actin-dependent myosin-I MYO5(gene name synonym) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343246|imex:IM-14275-2665 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR109W_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0009651"(response to salt stress)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051286"(cell tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071944"(cell periphery)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035535|ensemblfungi:YMR109W(gene)|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|rcsb pdb:1YP5|rcsb pdb:1ZUY|refseq:NP_013827.1|sgd:S000004715|mint:Q04439|dip:DIP-2222N ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) crc64:DFFB9EC16B61CD29 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:n/Po/L9Xd7LP+fY39QaqP/s5US4559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:21554ECAE13F05B4|rigid:HS+VyATY1+B1mvwqT0+BEVJ2ol8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04439 uniprotkb:P37370 intact:EBI-11687|ensemblfungi:YMR109W|uniprotkb:D6VZT2 intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C psi-mi:myo5_yeast(display_long)|uniprotkb:MYO5(gene name)|psi-mi:MYO5(display_short)|uniprotkb:YMR109W(locus name)|uniprotkb:YM9718.08(orf name)|uniprotkb:Class I unconventional myosin MYO5(gene name synonym)|uniprotkb:Type I myosin MYO5(gene name synonym)|uniprotkb:Actin-dependent myosin-I MYO5(gene name synonym) psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343257|imex:IM-14275-2666 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR109W_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0009651"(response to salt stress)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051286"(cell tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071944"(cell periphery)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035535|ensemblfungi:YMR109W(gene)|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|rcsb pdb:1YP5|rcsb pdb:1ZUY|refseq:NP_013827.1|sgd:S000004715|mint:Q04439|dip:DIP-2222N refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370 psi-mi:"MI:0469"(intact) crc64:DFFB9EC16B61CD29 crc64:24C7522D5B1CA1C8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:n/Po/L9Xd7LP+fY39QaqP/s5US4559292 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 intact-crc:EA7F02B4C51690B4|rigid:8rifUtjHPNUB2wU6+PqBPByzH6g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38328 uniprotkb:Q04439 intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C intact:EBI-11687|ensemblfungi:YMR109W|uniprotkb:D6VZT2 psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:myo5_yeast(display_long)|uniprotkb:MYO5(gene name)|psi-mi:MYO5(display_short)|uniprotkb:YMR109W(locus name)|uniprotkb:YM9718.08(orf name)|uniprotkb:Class I unconventional myosin MYO5(gene name synonym)|uniprotkb:Type I myosin MYO5(gene name synonym)|uniprotkb:Actin-dependent myosin-I MYO5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343268|imex:IM-14275-2667 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 ensemblfungi:YMR109W_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0009651"(response to salt stress)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051286"(cell tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071944"(cell periphery)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035535|ensemblfungi:YMR109W(gene)|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|rcsb pdb:1YP5|rcsb pdb:1ZUY|refseq:NP_013827.1|sgd:S000004715|mint:Q04439|dip:DIP-2222N psi-mi:"MI:0469"(intact) crc64:D75C6BB8EC35EEDF crc64:DFFB9EC16B61CD29 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 rogid:n/Po/L9Xd7LP+fY39QaqP/s5US4559292 intact-crc:6E95F5BE3892F784|rigid:hvajvy/aypgTkcHqWZRDMmTvGa0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38822 uniprotkb:Q04439 intact:EBI-3889|uniprotkb:E9P8V2|uniprotkb:D3DL64|ensemblfungi:YHR114W intact:EBI-11687|ensemblfungi:YMR109W|uniprotkb:D6VZT2 psi-mi:bzz1_yeast(display_long)|uniprotkb:BZZ1(gene name)|psi-mi:BZZ1(display_short)|uniprotkb:LAS17-binding protein 7(gene name synonym)|uniprotkb:LSB7(gene name synonym)|uniprotkb:YHR114W(locus name) psi-mi:myo5_yeast(display_long)|uniprotkb:MYO5(gene name)|psi-mi:MYO5(display_short)|uniprotkb:YMR109W(locus name)|uniprotkb:YM9718.08(orf name)|uniprotkb:Class I unconventional myosin MYO5(gene name synonym)|uniprotkb:Type I myosin MYO5(gene name synonym)|uniprotkb:Actin-dependent myosin-I MYO5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343279|imex:IM-14275-2668 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011982.1|sgd:S000001156|dip:DIP-2143N|mint:P38822|ensemblfungi:YHR114W(gene)|ensemblfungi:YHR114W_mRNA(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009651"(response to salt stress)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:1ZUU|rcsb pdb:2A28|reactome:R-SCE-8856828|reactome:R-SCE-9013406|reactome:R-SCE-9696270 ensemblfungi:YMR109W_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0009651"(response to salt stress)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051286"(cell tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071944"(cell periphery)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035535|ensemblfungi:YMR109W(gene)|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|rcsb pdb:1YP5|rcsb pdb:1ZUY|refseq:NP_013827.1|sgd:S000004715|mint:Q04439|dip:DIP-2222N psi-mi:"MI:0469"(intact) crc64:5C73DACC69611B41 crc64:DFFB9EC16B61CD29 figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lnoTdZ+pWCE2mDz3Ha7VQOOCfM8559292 rogid:n/Po/L9Xd7LP+fY39QaqP/s5US4559292 intact-crc:30DD89E2A1A52956|rigid:sV7O0wLrCzQ2OuQ31UdtlUTfA8c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04439 uniprotkb:P40518 intact:EBI-11687|ensemblfungi:YMR109W|uniprotkb:D6VZT2 intact:EBI-2750|uniprotkb:D6VVM2|ensemblfungi:YIL062C psi-mi:myo5_yeast(display_long)|uniprotkb:MYO5(gene name)|psi-mi:MYO5(display_short)|uniprotkb:YMR109W(locus name)|uniprotkb:YM9718.08(orf name)|uniprotkb:Class I unconventional myosin MYO5(gene name synonym)|uniprotkb:Type I myosin MYO5(gene name synonym)|uniprotkb:Actin-dependent myosin-I MYO5(gene name synonym) psi-mi:arpc5_yeast(display_long)|uniprotkb:ARC15(gene name)|psi-mi:ARC15(display_short)|uniprotkb:Arp2/3 complex 16 kDa subunit(gene name synonym)|uniprotkb:YIL062C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343290|imex:IM-14275-2669 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR109W_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0009651"(response to salt stress)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051286"(cell tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071944"(cell periphery)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035535|ensemblfungi:YMR109W(gene)|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|rcsb pdb:1YP5|rcsb pdb:1ZUY|refseq:NP_013827.1|sgd:S000004715|mint:Q04439|dip:DIP-2222N refseq:NP_012202.1|sgd:S000001324|dip:DIP-2101N|mint:P40518|ensemblfungi:YIL062C(gene)|ensemblfungi:YIL062C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR036743|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-6798695|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:DFFB9EC16B61CD29 crc64:10E4DAF0F0801B02 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:n/Po/L9Xd7LP+fY39QaqP/s5US4559292 rogid:iQ0mLisINMjXPulrRyDmrLcdpzU559292 intact-crc:3893303A124ED7CD|rigid:0/cO4692vC8bKY8ICNFW/lrAW5Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04439 uniprotkb:P53066 intact:EBI-11687|ensemblfungi:YMR109W|uniprotkb:D6VZT2 intact:EBI-24202|uniprotkb:D6VV93|ensemblfungi:YGL242C psi-mi:myo5_yeast(display_long)|uniprotkb:MYO5(gene name)|psi-mi:MYO5(display_short)|uniprotkb:YMR109W(locus name)|uniprotkb:YM9718.08(orf name)|uniprotkb:Class I unconventional myosin MYO5(gene name synonym)|uniprotkb:Type I myosin MYO5(gene name synonym)|uniprotkb:Actin-dependent myosin-I MYO5(gene name synonym) psi-mi:ygz2_yeast(display_long)|uniprotkb:HRE181(orf name)|uniprotkb:YGL242C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343301|imex:IM-14275-2670 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR109W_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0009651"(response to salt stress)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051286"(cell tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071944"(cell periphery)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035535|ensemblfungi:YMR109W(gene)|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|rcsb pdb:1YP5|rcsb pdb:1ZUY|refseq:NP_013827.1|sgd:S000004715|mint:Q04439|dip:DIP-2222N refseq:NP_011272.1|sgd:S000003211|dip:DIP-1859N|mint:P53066|ensemblfungi:YGL242C(gene)|ensemblfungi:YGL242C_mRNA(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 psi-mi:"MI:0469"(intact) crc64:DFFB9EC16B61CD29 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:n/Po/L9Xd7LP+fY39QaqP/s5US4559292 rogid:J/gcQo+pyiSh+k0KSepHBQj02cQ559292 intact-crc:36581A4808B36DC4|rigid:iIstlkppKzm7Ez6wk43rEnsNUzg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04439 uniprotkb:Q04439 intact:EBI-11687|ensemblfungi:YMR109W|uniprotkb:D6VZT2 intact:EBI-11687|ensemblfungi:YMR109W|uniprotkb:D6VZT2 psi-mi:myo5_yeast(display_long)|uniprotkb:MYO5(gene name)|psi-mi:MYO5(display_short)|uniprotkb:YMR109W(locus name)|uniprotkb:YM9718.08(orf name)|uniprotkb:Class I unconventional myosin MYO5(gene name synonym)|uniprotkb:Type I myosin MYO5(gene name synonym)|uniprotkb:Actin-dependent myosin-I MYO5(gene name synonym) psi-mi:myo5_yeast(display_long)|uniprotkb:MYO5(gene name)|psi-mi:MYO5(display_short)|uniprotkb:YMR109W(locus name)|uniprotkb:YM9718.08(orf name)|uniprotkb:Class I unconventional myosin MYO5(gene name synonym)|uniprotkb:Type I myosin MYO5(gene name synonym)|uniprotkb:Actin-dependent myosin-I MYO5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343312|imex:IM-14275-2671 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR109W_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0009651"(response to salt stress)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051286"(cell tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071944"(cell periphery)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035535|ensemblfungi:YMR109W(gene)|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|rcsb pdb:1YP5|rcsb pdb:1ZUY|refseq:NP_013827.1|sgd:S000004715|mint:Q04439|dip:DIP-2222N ensemblfungi:YMR109W_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0009651"(response to salt stress)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051286"(cell tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071944"(cell periphery)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035535|ensemblfungi:YMR109W(gene)|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|rcsb pdb:1YP5|rcsb pdb:1ZUY|refseq:NP_013827.1|sgd:S000004715|mint:Q04439|dip:DIP-2222N psi-mi:"MI:0469"(intact) crc64:DFFB9EC16B61CD29 crc64:DFFB9EC16B61CD29 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:n/Po/L9Xd7LP+fY39QaqP/s5US4559292 rogid:n/Po/L9Xd7LP+fY39QaqP/s5US4559292 intact-crc:B74C50C1D34527AF|rigid:00hJ6fpVAtn0syqpD+fdrvixb/g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12446 uniprotkb:Q04439 intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W intact:EBI-11687|ensemblfungi:YMR109W|uniprotkb:D6VZT2 psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name) psi-mi:myo5_yeast(display_long)|uniprotkb:MYO5(gene name)|psi-mi:MYO5(display_short)|uniprotkb:YMR109W(locus name)|uniprotkb:YM9718.08(orf name)|uniprotkb:Class I unconventional myosin MYO5(gene name synonym)|uniprotkb:Type I myosin MYO5(gene name synonym)|uniprotkb:Actin-dependent myosin-I MYO5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343323|imex:IM-14275-2672 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446 ensemblfungi:YMR109W_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0009651"(response to salt stress)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051286"(cell tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071944"(cell periphery)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035535|ensemblfungi:YMR109W(gene)|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|rcsb pdb:1YP5|rcsb pdb:1ZUY|refseq:NP_013827.1|sgd:S000004715|mint:Q04439|dip:DIP-2222N psi-mi:"MI:0469"(intact) crc64:4488355563AA2645 crc64:DFFB9EC16B61CD29 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292 rogid:n/Po/L9Xd7LP+fY39QaqP/s5US4559292 intact-crc:12594FA33E505CC7|rigid:k8MpNHdkBItzyIc/PsT/Al6t7Nc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04493 uniprotkb:P52553 intact:EBI-13253|uniprotkb:D6W0J1|ensemblfungi:YML094W intact:EBI-13260|uniprotkb:D6VYK2|ensemblfungi:YLR200W psi-mi:pfd5_yeast(display_long)|uniprotkb:GIM5(gene name)|psi-mi:GIM5(display_short)|uniprotkb:PFD5(gene name synonym)|uniprotkb:YML094W(locus name)|uniprotkb:Genes involved in microtubule biogenesis protein 5(gene name synonym)|uniprotkb:Gim complex subunit 5(gene name synonym) psi-mi:pfd6_yeast(display_long)|uniprotkb:YKE2(gene name)|psi-mi:YKE2(display_short)|uniprotkb:PFD6(gene name synonym)|uniprotkb:YLR200W(locus name)|uniprotkb:L8167.8(orf name)|uniprotkb:GIM1(gene name synonym)|uniprotkb:Genes involved in microtubule biogenesis protein 1(gene name synonym)|uniprotkb:Gim complex subunit 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343334|imex:IM-14275-2673 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013616.1|sgd:S000004559|mint:Q04493|dip:DIP-1332N|ensemblfungi:YML094W(gene)|ensemblfungi:YML094W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR011599(Prefoldin alpha subunit) refseq:NP_013301.1|sgd:S000004190|mint:P52553|dip:DIP-1333N|ensemblfungi:YLR200W(gene)|ensemblfungi:YLR200W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+I6WXFpL1knsCu3DsbMiC4LqDVo559292 rogid:XXTSrL5Q5CrSqYzKV3j3h5/7d10559292 intact-crc:30AD37DD54D35644|rigid:+4W9OKgtojJb6Ia2JoaLyW7FCxg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33750 uniprotkb:Q04500 intact:EBI-17651|uniprotkb:D6VXZ1|ensemblfungi:YLL011W intact:EBI-27917|uniprotkb:D6W0J2|ensemblfungi:YML093W psi-mi:dca13_yeast(display_long)|uniprotkb:SOF1(gene name)|psi-mi:SOF1(display_short)|uniprotkb:YLL011W(locus name)|uniprotkb:L1339(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein SOF1(gene name synonym) psi-mi:utp14_yeast(display_long)|uniprotkb:YML093W(locus name)|uniprotkb:U three protein 14(gene name synonym)|uniprotkb:UTP14(gene name)|psi-mi:UTP14(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343345|imex:IM-14275-2674 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLL011W(gene)|ensemblfungi:YLL011W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR007287(Sof1-like protein)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_013090.1|sgd:S000003934|dip:DIP-746N|mint:P33750 refseq:NP_013617.1|sgd:S000004558|dip:DIP-6410N|mint:Q04500|ensemblfungi:YML093W(gene)|ensemblfungi:YML093W_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0032040"(small-subunit processome)|interpro:IPR006709(Small-subunit processome, Utp14)|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQG|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:4B28371CC61DE7E4 crc64:0D4FC90D1CB3CFF1 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:stTLdABNsa3SvTkNOZBteSNAVJA559292 rogid:qK1PLcsc58zlpaWpK/18rTqXH/Q559292 intact-crc:763BFD83A7601172|rigid:K9OLdxrO90NUtgCPtl4HT3mfCho false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03944 uniprotkb:Q04638 intact:EBI-30418|uniprotkb:D6VSI2|ensemblfungi:YDR200C intact:EBI-27858|uniprotkb:D6VZA5|ensemblfungi:YML068W psi-mi:vps64_yeast(display_long)|uniprotkb:FAR9(gene name synonym)|uniprotkb:YD9346.10C(orf name)|uniprotkb:YDR200C(locus name)|uniprotkb:Factor arrest protein 9(gene name synonym)|uniprotkb:VPS64(gene name)|psi-mi:VPS64(display_short) psi-mi:itt1_yeast(display_long)|uniprotkb:ITT1(gene name)|psi-mi:ITT1(display_short)|uniprotkb:YML068W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343356|imex:IM-14275-2675 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002608|refseq:NP_010486.3|dip:DIP-1829N|mint:Q03944|ensemblfungi:YDR200C(gene)|ensemblfungi:YDR200C_mRNA(transcript)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031929"(TOR signaling)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|rcsb pdb:6A8W refseq:NP_013643.1|sgd:S000004533|dip:DIP-1952N|mint:Q04638|ensemblfungi:YML068W(gene)|ensemblfungi:YML068W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|interpro:IPR044066 psi-mi:"MI:0469"(intact) crc64:A22CEDD852FC421A crc64:F481372B742AF63D figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2jtSiV8992Ex17eb08gYie5/yzM559292 rogid:gPNBZ7jeo4QD4M26MqrTGBZqVZY559292 intact-crc:956DFCD942C2ED6F|rigid:p1USo1+bxA14UKbi6NS5aSQftSA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04651 uniprotkb:P39727 intact:EBI-27850|uniprotkb:E9PAD9|uniprotkb:D6VZA6|ensemblfungi:YML067C intact:EBI-20659|uniprotkb:D6VPH4|ensemblfungi:YAL042W psi-mi:erv41_yeast(display_long)|uniprotkb:YML067C(locus name)|uniprotkb:ERV41(gene name)|psi-mi:ERV41(display_short) psi-mi:erv46_yeast(display_long)|uniprotkb:FUN9(orf name)|uniprotkb:YAL042W(locus name)|uniprotkb:ERV46(gene name)|psi-mi:ERV46(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343367|imex:IM-14275-2676 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013644.1|sgd:S000004532|dip:DIP-6791N|mint:Q04651|ensemblfungi:YML067C(gene)|ensemblfungi:YML067C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|rcsb pdb:3ZLC refseq:NP_009358.1|sgd:S000000040|ensemblfungi:YAL042W(gene)|ensemblfungi:YAL042W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|dip:DIP-3792N|mint:P39727 psi-mi:"MI:0469"(intact) - crc64:FB7BC171B88BB5EA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IpGpvBxckHz1ExXTnTsKEHU2su8559292 rogid:tVyaLk7odK7bfnaz1FMv0E9lgtU559292 intact-crc:F37DEE9C0C128D8B|rigid:RxRVkGV0ee3X9a8C2VOpR6zOqbo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41810 uniprotkb:Q04651 intact:EBI-4869|uniprotkb:Q03779|uniprotkb:D6VSL9|ensemblfungi:YDR238C intact:EBI-27850|uniprotkb:E9PAD9|uniprotkb:D6VZA6|ensemblfungi:YML067C psi-mi:copb_yeast(display_long)|uniprotkb:SEC26(gene name)|psi-mi:SEC26(display_short)|uniprotkb:YDR238C(locus name)|uniprotkb:YD8419.05C(orf name)|uniprotkb:Beta-coat protein(gene name synonym) psi-mi:erv41_yeast(display_long)|uniprotkb:YML067C(locus name)|uniprotkb:ERV41(gene name)|psi-mi:ERV41(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343378|imex:IM-14275-2677 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002646|refseq:NP_010524.3|dip:DIP-6467N|mint:P41810|ensemblfungi:YDR238C(gene)|ensemblfungi:YDR238C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|reactome:R-SCE-6798695|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_013644.1|sgd:S000004532|dip:DIP-6791N|mint:Q04651|ensemblfungi:YML067C(gene)|ensemblfungi:YML067C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|rcsb pdb:3ZLC psi-mi:"MI:0469"(intact) crc64:885420DB026BCFA3 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZfLp1BUmvVuTiXn7/Zbf/3m6VtE559292 rogid:IpGpvBxckHz1ExXTnTsKEHU2su8559292 intact-crc:DBEF4207148332B9|rigid:fsfHs47WTqnKqLJlwDFj6Kt7A5M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04651 uniprotkb:Q04651 intact:EBI-27850|uniprotkb:E9PAD9|uniprotkb:D6VZA6|ensemblfungi:YML067C intact:EBI-27850|uniprotkb:E9PAD9|uniprotkb:D6VZA6|ensemblfungi:YML067C psi-mi:erv41_yeast(display_long)|uniprotkb:YML067C(locus name)|uniprotkb:ERV41(gene name)|psi-mi:ERV41(display_short) psi-mi:erv41_yeast(display_long)|uniprotkb:YML067C(locus name)|uniprotkb:ERV41(gene name)|psi-mi:ERV41(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343389|imex:IM-14275-2678 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013644.1|sgd:S000004532|dip:DIP-6791N|mint:Q04651|ensemblfungi:YML067C(gene)|ensemblfungi:YML067C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|rcsb pdb:3ZLC refseq:NP_013644.1|sgd:S000004532|dip:DIP-6791N|mint:Q04651|ensemblfungi:YML067C(gene)|ensemblfungi:YML067C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|rcsb pdb:3ZLC psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IpGpvBxckHz1ExXTnTsKEHU2su8559292 rogid:IpGpvBxckHz1ExXTnTsKEHU2su8559292 intact-crc:C57FE29DCE3D0A97|rigid:asEMriC0Q7TwsJO370qWf+LLicA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:Q04651 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-27850|uniprotkb:E9PAD9|uniprotkb:D6VZA6|ensemblfungi:YML067C psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:erv41_yeast(display_long)|uniprotkb:YML067C(locus name)|uniprotkb:ERV41(gene name)|psi-mi:ERV41(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343400|imex:IM-14275-2679 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 refseq:NP_013644.1|sgd:S000004532|dip:DIP-6791N|mint:Q04651|ensemblfungi:YML067C(gene)|ensemblfungi:YML067C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|rcsb pdb:3ZLC psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:IpGpvBxckHz1ExXTnTsKEHU2su8559292 intact-crc:E550BDD94299F454|rigid:QUkm1yQ94BNJ22Kgfcu1ishCtMM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04792 uniprotkb:Q04792 intact:EBI-5668|uniprotkb:D6W076|ensemblfungi:YMR250W intact:EBI-5668|uniprotkb:D6W076|ensemblfungi:YMR250W psi-mi:dce_yeast(display_long)|uniprotkb:YM9920.04(orf name)|uniprotkb:YMR250W(locus name)|uniprotkb:GAD1(gene name)|psi-mi:GAD1(display_short) psi-mi:dce_yeast(display_long)|uniprotkb:YM9920.04(orf name)|uniprotkb:YMR250W(locus name)|uniprotkb:GAD1(gene name)|psi-mi:GAD1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343411|imex:IM-14275-2680 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013976.1|sgd:S000004862|dip:DIP-2552N|mint:Q04792|ensemblfungi:YMR250W(gene)|ensemblfungi:YMR250W_mRNA(transcript)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034599"(cellular response to oxidative stress)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR010107(Glutamate decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region) refseq:NP_013976.1|sgd:S000004862|dip:DIP-2552N|mint:Q04792|ensemblfungi:YMR250W(gene)|ensemblfungi:YMR250W_mRNA(transcript)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034599"(cellular response to oxidative stress)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR010107(Glutamate decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:NQkdD5OXZZFLwhkVd3UizNw/5S8559292 rogid:NQkdD5OXZZFLwhkVd3UizNw/5S8559292 intact-crc:EE05ED36F22F8109|rigid:P2ApGcV9Oel1qtNwb7+QRBvaAGw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04839 uniprotkb:P39936 intact:EBI-27549|uniprotkb:D6W081|ensemblfungi:YMR255W intact:EBI-9006|ensemblfungi:YGL049C|uniprotkb:D6VU91 psi-mi:gfd1_yeast(display_long)|uniprotkb:GFD1(gene name)|psi-mi:GFD1(display_short)|uniprotkb:YMR255W(locus name)|uniprotkb:YM9920.09(orf name)|uniprotkb:Good for full DBP5 activity protein 1(gene name synonym) psi-mi:if4f2_yeast(display_long)|uniprotkb:YGL049C(locus name)|uniprotkb:TIF4632(gene name)|psi-mi:TIF4632(display_short)|uniprotkb:eIF4G2(gene name synonym)|uniprotkb:mRNA cap-binding protein complex subunit p130(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343422|imex:IM-14275-2681 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004868|refseq:NP_013982.1|dip:DIP-1254N|mint:Q04839|ensemblfungi:YMR255W(gene)|ensemblfungi:YMR255W_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015031"(protein transport)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:3LCN interpro:IPR036211|reactome:R-SCE-156827|reactome:R-SCE-166208|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-72662|reactome:R-SCE-72702|reactome:R-SCE-975956|reactome:R-SCE-975957|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0034063"(stress granule assembly)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|go:"GO:1902280"(regulation of RNA helicase activity)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022745|ensemblfungi:YGL049C(gene)|ensemblfungi:YGL049C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|refseq:NP_011466.1|sgd:S000003017|mint:P39936|dip:DIP-330N psi-mi:"MI:0469"(intact) - crc64:BF5E9805CD47908E figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2IqMWMpym7QObadY7Qq00tunNHs559292 rogid:T8feENVEclKiN5joAyBJ2trBE0A559292 intact-crc:0F6694BD25533071|rigid:/ohb9tut0WG3vRuNGc7dN62kel4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02884 uniprotkb:Q04868 intact:EBI-35277|uniprotkb:D6W3R5|ensemblfungi:YPL101W intact:EBI-27653|uniprotkb:D6W0D9|ensemblfungi:YMR312W psi-mi:elp4_yeast(display_long)|uniprotkb:ELP4(gene name)|psi-mi:ELP4(display_short)|uniprotkb:Gamma-toxin target 7(gene name synonym)|uniprotkb:HAT-associated protein 1(gene name synonym)|uniprotkb:YPL101W(locus name)|uniprotkb:HAP1(gene name synonym)|uniprotkb:TOT7(gene name synonym) psi-mi:elp6_yeast(display_long)|uniprotkb:YMR312W(locus name)|uniprotkb:YM9924.04(orf name)|uniprotkb:ELP6(gene name)|psi-mi:ELP6(display_short)|uniprotkb:HAP3(gene name synonym)|uniprotkb:TOT6(gene name synonym)|uniprotkb:Gamma-toxin target 6(gene name synonym)|uniprotkb:HAT-associated protein 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343433|imex:IM-14275-2682 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015224.1|sgd:S000006022|mint:Q02884|dip:DIP-6718N|ensemblfungi:YPL101W(gene)|ensemblfungi:YPL101W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR008728(PAXNEB)|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS refseq:NP_014043.1|sgd:S000004929|dip:DIP-1966N|mint:Q04868|ensemblfungi:YMR312W(gene)|ensemblfungi:YMR312W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032447"(protein urmylation)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR018627|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS psi-mi:"MI:0469"(intact) crc64:276F0D1538EAA8FA crc64:1A5062465AF67F47 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:LLHmiDxhPIIxIElMn9yVWoFnY4Q559292 rogid:Nyp6/02bMFUoG//crZCg98Eepc8559292 intact-crc:2DB190A1A88FA8B4|rigid:BTQ+2isArwCK2AF7MNUKyS7m5cU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04949 uniprotkb:P22211 intact:EBI-27644|uniprotkb:Q03592|uniprotkb:D6W0C6|ensemblfungi:YMR299C intact:EBI-12207|uniprotkb:D6W103|ensemblfungi:YNL183C psi-mi:dyn3_yeast(display_long)|uniprotkb:YM9952.01C(orf name)|uniprotkb:YMR299C(locus name)|uniprotkb:DYN3(gene name)|psi-mi:DYN3(display_short) psi-mi:npr1_yeast(display_long)|uniprotkb:NPR1(gene name)|psi-mi:NPR1(display_short)|uniprotkb:YNL183C(locus name)|uniprotkb:N1631(orf name)|uniprotkb:Serine/threonine-protein kinase NPR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343444|imex:IM-14275-2683 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004914|refseq:NP_014028.2|dip:DIP-7271N|mint:Q04949|ensemblfungi:YMR299C(gene)|ensemblfungi:YMR299C_mRNA(transcript)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0030473"(nuclear migration along microtubule)|interpro:IPR022780 ensemblfungi:YNL183C(gene)|ensemblfungi:YNL183C_mRNA(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0090153"(regulation of sphingolipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:NP_014216.1|sgd:S000005127|dip:DIP-4327N|mint:P22211 psi-mi:"MI:0469"(intact) - crc64:0ECFA33376740733 figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:u8KE//uQu/Y0UVnesbu19B6oQQI559292 rogid:vpnDA3eDZQvh0DCkfcTkxzfCEvY559292 intact-crc:8D68FB6E86B2E68E|rigid:oTFpRFNShiMAXSoQDagjtk3M7/o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04949 uniprotkb:P36027 intact:EBI-27644|uniprotkb:Q03592|uniprotkb:D6W0C6|ensemblfungi:YMR299C intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:dyn3_yeast(display_long)|uniprotkb:YM9952.01C(orf name)|uniprotkb:YMR299C(locus name)|uniprotkb:DYN3(gene name)|psi-mi:DYN3(display_short) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343455|imex:IM-14275-2684 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004914|refseq:NP_014028.2|dip:DIP-7271N|mint:Q04949|ensemblfungi:YMR299C(gene)|ensemblfungi:YMR299C_mRNA(transcript)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0030473"(nuclear migration along microtubule)|interpro:IPR022780 ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:u8KE//uQu/Y0UVnesbu19B6oQQI559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:6F56D97E6CF955A8|rigid:Rx/4JByWsBCoG1wJIPOGVA4kefA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04949 uniprotkb:P50276 intact:EBI-27644|uniprotkb:Q03592|uniprotkb:D6W0C6|ensemblfungi:YMR299C intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:dyn3_yeast(display_long)|uniprotkb:YM9952.01C(orf name)|uniprotkb:YMR299C(locus name)|uniprotkb:DYN3(gene name)|psi-mi:DYN3(display_short) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343466|imex:IM-14275-2685 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004914|refseq:NP_014028.2|dip:DIP-7271N|mint:Q04949|ensemblfungi:YMR299C(gene)|ensemblfungi:YMR299C_mRNA(transcript)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0030473"(nuclear migration along microtubule)|interpro:IPR022780 ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:u8KE//uQu/Y0UVnesbu19B6oQQI559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:ECE41A4F80713374|rigid:297Obb7CO+X6nIYYr6mm04omLwA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04949 uniprotkb:P53289 intact:EBI-27644|uniprotkb:Q03592|uniprotkb:D6W0C6|ensemblfungi:YMR299C intact:EBI-23393|uniprotkb:D6VUU0|uniprotkb:Q7ZA12|ensemblfungi:YGR161C psi-mi:dyn3_yeast(display_long)|uniprotkb:YM9952.01C(orf name)|uniprotkb:YMR299C(locus name)|uniprotkb:DYN3(gene name)|psi-mi:DYN3(display_short) psi-mi:rts3_yeast(display_long)|uniprotkb:RTS3(gene name)|psi-mi:RTS3(display_short)|uniprotkb:YGR161C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343477|imex:IM-14275-2686 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004914|refseq:NP_014028.2|dip:DIP-7271N|mint:Q04949|ensemblfungi:YMR299C(gene)|ensemblfungi:YMR299C_mRNA(transcript)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0030473"(nuclear migration along microtubule)|interpro:IPR022780 sgd:S000003393|refseq:NP_011677.3|dip:DIP-6319N|mint:P53289|ensemblfungi:YGR161C(gene)|ensemblfungi:YGR161C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm) psi-mi:"MI:0469"(intact) - crc64:BA31D32B9ADF02AB figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:u8KE//uQu/Y0UVnesbu19B6oQQI559292 rogid:0xYKXiuXiyBDogpuE8vOl7hUekQ559292 intact-crc:92CEECA66B289566|rigid:eyTL/bFRHyCh27LI4Z4Vm1T2i/g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02785 uniprotkb:Q04949 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C intact:EBI-27644|uniprotkb:Q03592|uniprotkb:D6W0C6|ensemblfungi:YMR299C psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:dyn3_yeast(display_long)|uniprotkb:YM9952.01C(orf name)|uniprotkb:YMR299C(locus name)|uniprotkb:DYN3(gene name)|psi-mi:DYN3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343488|imex:IM-14275-2687 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) sgd:S000004914|refseq:NP_014028.2|dip:DIP-7271N|mint:Q04949|ensemblfungi:YMR299C(gene)|ensemblfungi:YMR299C_mRNA(transcript)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0030473"(nuclear migration along microtubule)|interpro:IPR022780 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 rogid:u8KE//uQu/Y0UVnesbu19B6oQQI559292 intact-crc:2111992C77557A4A|rigid:yLXgp/oMktNwhoborT/J7C19Th4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:Q04969 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-27827|uniprotkb:D6VZB9|ensemblfungi:YML055W psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:spc2_yeast(display_long)|uniprotkb:YML055W(locus name)|uniprotkb:YM9958.07(orf name)|uniprotkb:SPC2(gene name)|psi-mi:SPC2(display_short)|uniprotkb:SPY1(gene name synonym)|uniprotkb:Microsomal signal peptidase subunit 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343499|imex:IM-14275-2688 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_013657.1|sgd:S000004519|dip:DIP-4540N|mint:Q04969|ensemblfungi:YML055W(gene)|ensemblfungi:YML055W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:ZXf9rPA3/ryPnDqI4JGp0VMNMe4559292 intact-crc:1A5717ED29540BE9|rigid:MJeRSwJlXwbDDD8BVO9ru+YWPrE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04969 uniprotkb:P21825 intact:EBI-27827|uniprotkb:D6VZB9|ensemblfungi:YML055W intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 psi-mi:spc2_yeast(display_long)|uniprotkb:YML055W(locus name)|uniprotkb:YM9958.07(orf name)|uniprotkb:SPC2(gene name)|psi-mi:SPC2(display_short)|uniprotkb:SPY1(gene name synonym)|uniprotkb:Microsomal signal peptidase subunit 2(gene name synonym) psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343510|imex:IM-14275-2689 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013657.1|sgd:S000004519|dip:DIP-4540N|mint:Q04969|ensemblfungi:YML055W(gene)|ensemblfungi:YML055W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit) ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZXf9rPA3/ryPnDqI4JGp0VMNMe4559292 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 intact-crc:96D4B5B93AD4796A|rigid:vbojyQvFLsoBMwkEksKqBrXJ804 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:Q04969 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-27827|uniprotkb:D6VZB9|ensemblfungi:YML055W psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:spc2_yeast(display_long)|uniprotkb:YML055W(locus name)|uniprotkb:YM9958.07(orf name)|uniprotkb:SPC2(gene name)|psi-mi:SPC2(display_short)|uniprotkb:SPY1(gene name synonym)|uniprotkb:Microsomal signal peptidase subunit 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343521|imex:IM-14275-2690 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N refseq:NP_013657.1|sgd:S000004519|dip:DIP-4540N|mint:Q04969|ensemblfungi:YML055W(gene)|ensemblfungi:YML055W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:ZXf9rPA3/ryPnDqI4JGp0VMNMe4559292 intact-crc:0D41153BF474B724|rigid:tLwuRcP7FYfOARSl7N9F0GlIWmw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04969 uniprotkb:P46965 intact:EBI-27827|uniprotkb:D6VZB9|ensemblfungi:YML055W intact:EBI-17823|uniprotkb:D6VWI6|ensemblfungi:YJR010C-A psi-mi:spc2_yeast(display_long)|uniprotkb:YML055W(locus name)|uniprotkb:YM9958.07(orf name)|uniprotkb:SPC2(gene name)|psi-mi:SPC2(display_short)|uniprotkb:SPY1(gene name synonym)|uniprotkb:Microsomal signal peptidase subunit 2(gene name synonym) psi-mi:spc1_yeast(display_long)|uniprotkb:SPC1(gene name)|psi-mi:SPC1(display_short)|uniprotkb:YJR010C-A(locus name)|uniprotkb:YJR010BW(orf name)|uniprotkb:Microsomal signal peptidase subunit 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343532|imex:IM-14275-2691 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013657.1|sgd:S000004519|dip:DIP-4540N|mint:Q04969|ensemblfungi:YML055W(gene)|ensemblfungi:YML055W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit) refseq:NP_012544.1|sgd:S000003770|ensemblfungi:YJR010C-A(gene)|ensemblfungi:YJR010C-A_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009542(Microsomal signal peptidase 12 kDa subunit)|interpro:IPR037713|mint:P46965|dip:DIP-2770N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZXf9rPA3/ryPnDqI4JGp0VMNMe4559292 rogid:kchUi3mkadvzweVkrWO3QkbbHew559292 intact-crc:D5CB5EFD6E253D5B|rigid:FJgD/eucrEVPEKrmQOQ1MuR5sD0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04969 uniprotkb:Q06144 intact:EBI-27827|uniprotkb:D6VZB9|ensemblfungi:YML055W intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:spc2_yeast(display_long)|uniprotkb:YML055W(locus name)|uniprotkb:YM9958.07(orf name)|uniprotkb:SPC2(gene name)|psi-mi:SPC2(display_short)|uniprotkb:SPY1(gene name synonym)|uniprotkb:Microsomal signal peptidase subunit 2(gene name synonym) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343543|imex:IM-14275-2692 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013657.1|sgd:S000004519|dip:DIP-4540N|mint:Q04969|ensemblfungi:YML055W(gene)|ensemblfungi:YML055W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:2F474503CAB7C195 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZXf9rPA3/ryPnDqI4JGp0VMNMe4559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 intact-crc:70E16D4DFFE8FD50|rigid:l80sforzkCZOz+1jP4wRvLBjrgk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04991 uniprotkb:P32798 intact:EBI-27478|uniprotkb:D6W046|ensemblfungi:YMR221C intact:EBI-5006|uniprotkb:D6W314|ensemblfungi:YOR316C psi-mi:fmp42_yeast(display_long)|uniprotkb:YM9959.03C(orf name)|uniprotkb:YMR221C(locus name)|uniprotkb:FMP42(gene name)|psi-mi:FMP42(display_short) psi-mi:cot1_yeast(display_long)|uniprotkb:COT1(gene name)|psi-mi:COT1(display_short)|uniprotkb:O6131(orf name)|uniprotkb:YOR316C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343554|imex:IM-14275-2693 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q04991|refseq:NP_013948.1|sgd:S000004834|dip:DIP-2606N|ensemblfungi:YMR221C(gene)|ensemblfungi:YMR221C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 sgd:S000005843|refseq:NP_014961.3|dip:DIP-7554N|mint:P32798|ensemblfungi:YOR316C(gene)|ensemblfungi:YOR316C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006824"(cobalt ion transport)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0015087"(cobalt ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:qXi1J03ZbZaVmV8rm5cqit1naAs559292 rogid:HEIg6lhS698E9H3BJeESYAipNwA559292 intact-crc:F69DEB9F3CE54DF7|rigid:Z/uT0OWR3P3sUVVbWXl1gZPanS8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04991 uniprotkb:P38310 intact:EBI-27478|uniprotkb:D6W046|ensemblfungi:YMR221C intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:fmp42_yeast(display_long)|uniprotkb:YM9959.03C(orf name)|uniprotkb:YMR221C(locus name)|uniprotkb:FMP42(gene name)|psi-mi:FMP42(display_short) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343565|imex:IM-14275-2694 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q04991|refseq:NP_013948.1|sgd:S000004834|dip:DIP-2606N|ensemblfungi:YMR221C(gene)|ensemblfungi:YMR221C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) - crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:qXi1J03ZbZaVmV8rm5cqit1naAs559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:9A22CA70F2D09A52|rigid:KDd6tnjEyvofGpdTZ1vpqREeQBw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04991 uniprotkb:P38929 intact:EBI-27478|uniprotkb:D6W046|ensemblfungi:YMR221C intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W psi-mi:fmp42_yeast(display_long)|uniprotkb:YM9959.03C(orf name)|uniprotkb:YMR221C(locus name)|uniprotkb:FMP42(gene name)|psi-mi:FMP42(display_short) psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343576|imex:IM-14275-2695 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q04991|refseq:NP_013948.1|sgd:S000004834|dip:DIP-2606N|ensemblfungi:YMR221C(gene)|ensemblfungi:YMR221C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 psi-mi:"MI:0469"(intact) - crc64:5BD9ECFF8508F396 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:qXi1J03ZbZaVmV8rm5cqit1naAs559292 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 intact-crc:B8240051A98EDB97|rigid:P9FLO217QnA4cWdUUz9820QUfGI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41807 uniprotkb:Q04991 intact:EBI-20281|uniprotkb:D6W446|ensemblfungi:YPR036W intact:EBI-27478|uniprotkb:D6W046|ensemblfungi:YMR221C psi-mi:vath_yeast(display_long)|uniprotkb:YP3085.02(orf name)|uniprotkb:VMA13(gene name)|psi-mi:VMA13(display_short)|uniprotkb:CLS11(gene name synonym)|uniprotkb:YPR036W(locus name)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 54 kDa subunit(gene name synonym) psi-mi:fmp42_yeast(display_long)|uniprotkb:YM9959.03C(orf name)|uniprotkb:YMR221C(locus name)|uniprotkb:FMP42(gene name)|psi-mi:FMP42(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343587|imex:IM-14275-2696 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015361.1|sgd:S000006240|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|rcsb pdb:1HO8|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YPR036W(gene)|ensemblfungi:YPR036W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|dip:DIP-6640N|mint:P41807 mint:Q04991|refseq:NP_013948.1|sgd:S000004834|dip:DIP-2606N|ensemblfungi:YMR221C(gene)|ensemblfungi:YMR221C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:54131FF9C2C87594 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kEXWvOsnTk0WdgGOny+mufz4lTo559292 rogid:qXi1J03ZbZaVmV8rm5cqit1naAs559292 intact-crc:7A310D8AE329270B|rigid:l/ZfEzp2oJ+TP8DJCB99Taa3Qic false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46989 uniprotkb:Q04991 intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C intact:EBI-27478|uniprotkb:D6W046|ensemblfungi:YMR221C psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:fmp42_yeast(display_long)|uniprotkb:YM9959.03C(orf name)|uniprotkb:YMR221C(locus name)|uniprotkb:FMP42(gene name)|psi-mi:FMP42(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343598|imex:IM-14275-2697 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 mint:Q04991|refseq:NP_013948.1|sgd:S000004834|dip:DIP-2606N|ensemblfungi:YMR221C(gene)|ensemblfungi:YMR221C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 rogid:qXi1J03ZbZaVmV8rm5cqit1naAs559292 intact-crc:F02EE093A21FDA1E|rigid:OudaIee3Mw9dFeWmBEqNX4dmzcI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05022 uniprotkb:P21304 intact:EBI-16011|uniprotkb:D6W054|ensemblfungi:YMR229C intact:EBI-14328|uniprotkb:D6VYJ9|ensemblfungi:YLR196W psi-mi:rrp5_yeast(display_long)|uniprotkb:RRP5(gene name)|psi-mi:RRP5(display_short)|uniprotkb:FMI1(gene name synonym)|uniprotkb:YMR229C(locus name)|uniprotkb:YM9959.11C(orf name)|uniprotkb:Ribosomal RNA-processing protein 5(gene name synonym)|uniprotkb:U3 small nucleolar RNA-associated protein RRP5(gene name synonym) psi-mi:pwp1_yeast(display_long)|uniprotkb:L8167.10(orf name)|uniprotkb:YLR196W(locus name)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343609|imex:IM-14275-2698 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013956.1|sgd:S000004842|ensemblfungi:YMR229C(gene)|ensemblfungi:YMR229C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000464"("endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034463"(90S preribosome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR003029(S1, RNA binding)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|rcsb pdb:5C9S|rcsb pdb:5NLG|rcsb pdb:5WLC|rcsb pdb:5WWM|rcsb pdb:5WYJ|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|dip:DIP-6535N|mint:Q05022 refseq:NP_013297.1|sgd:S000004186|ensemblfungi:YLR196W(gene)|ensemblfungi:YLR196W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR044285|mint:P21304|dip:DIP-4203N psi-mi:"MI:0469"(intact) crc64:39BF46E5587B3B0A crc64:FC0189B289494AB5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FUIsTk3NLRDu8llnVgX5cDLAbB8559292 rogid:Q1nPXtlkpIw8JosaiYX0PSVNaSw559292 intact-crc:EF454DE4BCCAD30E|rigid:Ck7gpPIPiCY3mVzVK6iieH8yS4Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39744 uniprotkb:Q05022 intact:EBI-29259|uniprotkb:Q08625|uniprotkb:D6W2R2|ensemblfungi:YOR206W intact:EBI-16011|uniprotkb:D6W054|ensemblfungi:YMR229C psi-mi:noc2_yeast(display_long)|uniprotkb:YOX001(orf name)|uniprotkb:YOR206W(locus name)|uniprotkb:NOC2(gene name)|psi-mi:NOC2(display_short) psi-mi:rrp5_yeast(display_long)|uniprotkb:RRP5(gene name)|psi-mi:RRP5(display_short)|uniprotkb:FMI1(gene name synonym)|uniprotkb:YMR229C(locus name)|uniprotkb:YM9959.11C(orf name)|uniprotkb:Ribosomal RNA-processing protein 5(gene name synonym)|uniprotkb:U3 small nucleolar RNA-associated protein RRP5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343620|imex:IM-14275-2699 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014849.3|sgd:S000005732|dip:DIP-4559N|mint:P39744|ensemblfungi:YOR206W(gene)|ensemblfungi:YOR206W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR005343(Protein of unknown function UPF0120) refseq:NP_013956.1|sgd:S000004842|ensemblfungi:YMR229C(gene)|ensemblfungi:YMR229C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000464"("endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034463"(90S preribosome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR003029(S1, RNA binding)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|rcsb pdb:5C9S|rcsb pdb:5NLG|rcsb pdb:5WLC|rcsb pdb:5WWM|rcsb pdb:5WYJ|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|dip:DIP-6535N|mint:Q05022 psi-mi:"MI:0469"(intact) crc64:48C3B9AE076B9B8F crc64:39BF46E5587B3B0A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:d5I8KJOSG63bZ/Pt+XvKdy/SWws559292 rogid:FUIsTk3NLRDu8llnVgX5cDLAbB8559292 intact-crc:F9364C03CF2DE566|rigid:Tpf8KL82yFTn5ZmM9vHrz1lzKCI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05022 uniprotkb:P40693 intact:EBI-16011|uniprotkb:D6W054|ensemblfungi:YMR229C intact:EBI-15415|uniprotkb:D6W1H5|ensemblfungi:YNL002C psi-mi:rrp5_yeast(display_long)|uniprotkb:RRP5(gene name)|psi-mi:RRP5(display_short)|uniprotkb:FMI1(gene name synonym)|uniprotkb:YMR229C(locus name)|uniprotkb:YM9959.11C(orf name)|uniprotkb:Ribosomal RNA-processing protein 5(gene name synonym)|uniprotkb:U3 small nucleolar RNA-associated protein RRP5(gene name synonym) psi-mi:rlp7_yeast(display_long)|uniprotkb:RPL7(gene name synonym)|uniprotkb:N2014(orf name)|uniprotkb:YNL002C(locus name)|uniprotkb:RLP7(gene name)|psi-mi:RLP7(display_short)|uniprotkb:Ribosomal protein L7-like(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343631|imex:IM-14275-2700 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013956.1|sgd:S000004842|ensemblfungi:YMR229C(gene)|ensemblfungi:YMR229C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000464"("endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034463"(90S preribosome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR003029(S1, RNA binding)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|rcsb pdb:5C9S|rcsb pdb:5NLG|rcsb pdb:5WLC|rcsb pdb:5WWM|rcsb pdb:5WYJ|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|dip:DIP-6535N|mint:Q05022 sgd:S000004947|refseq:NP_014396.3|ensemblfungi:YNL002C(gene)|ensemblfungi:YNL002C_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000465"("exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|rcsb pdb:3JCT|rcsb pdb:4V7F|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6M62|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BTB|dip:DIP-6476N|mint:P40693 psi-mi:"MI:0469"(intact) crc64:39BF46E5587B3B0A crc64:64714DDFAFB90B5D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FUIsTk3NLRDu8llnVgX5cDLAbB8559292 rogid:HR8kGX5foVbBQ/nWTKMM16uB3E8559292 intact-crc:950C41F9E9E6E3A3|rigid:IG4EWmzniFI2OQxjj8rx8pgvDLI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05022 uniprotkb:Q08235 intact:EBI-16011|uniprotkb:D6W054|ensemblfungi:YMR229C intact:EBI-3775|uniprotkb:D6W1Z1|ensemblfungi:YOL077C psi-mi:rrp5_yeast(display_long)|uniprotkb:RRP5(gene name)|psi-mi:RRP5(display_short)|uniprotkb:FMI1(gene name synonym)|uniprotkb:YMR229C(locus name)|uniprotkb:YM9959.11C(orf name)|uniprotkb:Ribosomal RNA-processing protein 5(gene name synonym)|uniprotkb:U3 small nucleolar RNA-associated protein RRP5(gene name synonym) psi-mi:brx1_yeast(display_long)|uniprotkb:YOL077C(locus name)|uniprotkb:BRX1(gene name)|psi-mi:BRX1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343642|imex:IM-14275-2701 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013956.1|sgd:S000004842|ensemblfungi:YMR229C(gene)|ensemblfungi:YMR229C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000464"("endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034463"(90S preribosome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR003029(S1, RNA binding)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|rcsb pdb:5C9S|rcsb pdb:5NLG|rcsb pdb:5WLC|rcsb pdb:5WWM|rcsb pdb:5WYJ|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|dip:DIP-6535N|mint:Q05022 refseq:NP_014565.2|sgd:S000005437|dip:DIP-6317N|mint:Q08235|ensemblfungi:YOL077C(gene)|ensemblfungi:YOL077C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000464"("endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000465"("exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR007109(Brix)|interpro:IPR026532|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5 psi-mi:"MI:0469"(intact) crc64:39BF46E5587B3B0A crc64:31466853EF0E7301 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FUIsTk3NLRDu8llnVgX5cDLAbB8559292 rogid:mPR6HWKwM6RNCRE/vezsYlCmEGY559292 intact-crc:76AFC354557E3BCF|rigid:KsWH8eWgOPa1Cwq/8qqgmcpJ730 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05031 uniprotkb:P39719 intact:EBI-27512|uniprotkb:D6W064|ensemblfungi:YMR238W intact:EBI-20703|uniprotkb:Q05165|uniprotkb:D6VPG5|ensemblfungi:YAL053W psi-mi:dfg5_yeast(display_long)|uniprotkb:DFG5(gene name)|psi-mi:DFG5(display_short)|uniprotkb:YMR238W(locus name)|uniprotkb:YM9959.20(orf name)|uniprotkb:Endo-alpha-1->6-D-mannanase DFG5(gene name synonym) psi-mi:flc2_yeast(display_long)|uniprotkb:YAL053W(locus name)|uniprotkb:FLC2(gene name)|psi-mi:FLC2(display_short)|uniprotkb:FAD transporter 2(gene name synonym)|uniprotkb:TRP-like ion channel FLC2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343653|imex:IM-14275-2702 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q05031|refseq:NP_013965.1|sgd:S000004851|dip:DIP-2739N|ensemblfungi:YMR238W(gene)|ensemblfungi:YMR238W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008496"(mannan endo-1,6-alpha-mannosidase activity)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0071555"(cell wall organization)|interpro:IPR005198(Glycoside hydrolase, family 76)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR014480(Mannan endo-1,6-alpha-mannosidase) refseq:NP_009348.2|sgd:S000000049|ensemblfungi:YAL053W(gene)|ensemblfungi:YAL053W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241|go:"GO:0055085"(transmembrane transport)|dip:DIP-6708N|mint:P39719 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nnHGptBCE3g8JbHRaiJvIbe4Nw8559292 rogid:NOmMW54DNa0o7vM945DlZgVUy44559292 intact-crc:F747E851320F5766|rigid:n902VhyPAcJYvA1nxtgI06hzfhE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05031 uniprotkb:Q06144 intact:EBI-27512|uniprotkb:D6W064|ensemblfungi:YMR238W intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:dfg5_yeast(display_long)|uniprotkb:DFG5(gene name)|psi-mi:DFG5(display_short)|uniprotkb:YMR238W(locus name)|uniprotkb:YM9959.20(orf name)|uniprotkb:Endo-alpha-1->6-D-mannanase DFG5(gene name synonym) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343664|imex:IM-14275-2703 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q05031|refseq:NP_013965.1|sgd:S000004851|dip:DIP-2739N|ensemblfungi:YMR238W(gene)|ensemblfungi:YMR238W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008496"(mannan endo-1,6-alpha-mannosidase activity)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0071555"(cell wall organization)|interpro:IPR005198(Glycoside hydrolase, family 76)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR014480(Mannan endo-1,6-alpha-mannosidase) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:2F474503CAB7C195 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nnHGptBCE3g8JbHRaiJvIbe4Nw8559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 intact-crc:2E6EE9D9024DF2B1|rigid:jK3I/FJNHUi7oVvTG6wzydbcAKs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05166 uniprotkb:P32500 intact:EBI-3035|uniprotkb:Q12456|uniprotkb:E9P903|uniprotkb:D6VRR0|ensemblfungi:YDL088C intact:EBI-11950|ensemblfungi:YML031W|uniprotkb:D6VZE3 psi-mi:nup59_yeast(display_long)|uniprotkb:ASM4(gene name)|psi-mi:ASM4(display_short)|uniprotkb:Nuclear pore protein NUP59(gene name synonym)|uniprotkb:NUP59(gene name synonym)|uniprotkb:D2420(orf name)|uniprotkb:YDL088C(locus name) psi-mi:ndc1_yeast(display_long)|uniprotkb:YML031W(locus name)|uniprotkb:NDC1(gene name)|psi-mi:NDC1(display_short)|uniprotkb:Nuclear pore protein NDC1(gene name synonym)|uniprotkb:Nuclear division cycle protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343675|imex:IM-14275-2704 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010195.1|sgd:S000002246|dip:DIP-1466N|mint:Q05166|ensemblfungi:YDL088C(gene)|ensemblfungi:YDL088C_mRNA(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007049"(cell cycle)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0051301"(cell division)|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017389(Nucleoporin, NUP53)|interpro:IPR035979 ensemblfungi:YML031W(gene)|ensemblfungi:YML031W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0070631"(spindle pole body localization)|go:"GO:0070762"(nuclear pore transmembrane ring)|go:"GO:0106166"(spindle pole body-nuclear membrane anchor activity)|interpro:IPR019049|go:"GO:0017056"(structural constituent of nuclear pore)|refseq:NP_013681.1|sgd:S000004493|mint:P32500|dip:DIP-1465N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:t8/JWDKB0Spe2P8qdZnKs/RB3SY559292 rogid:CJawnqL6UYhpSqsKMbif8ifzgUY559292 intact-crc:105353B72C57BD0E|rigid:ISJRySoF8A4QH55nfl6aOvr1q4E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:P10614 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343686|imex:IM-14275-2705 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:7220CF15B54C5564|rigid:AHvAsNmcEvv+EvhdTTZ9f/zvppM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:P11076 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343697|imex:IM-14275-2706 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 psi-mi:"MI:0469"(intact) - crc64:796859026AC63CC0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 intact-crc:98FB667DD42BFB19|rigid:WYZt+kxdhAu8TFvqkUpfeLRSEtg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17898 uniprotkb:Q05359 intact:EBI-2050738|uniprotkb:D6W152|ensemblfungi:YNL130C intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A psi-mi:cpt1_yeast(display_long)|uniprotkb:Diacylglycerol cholinephosphotransferase 1(gene name synonym)|uniprotkb:Sn-1,2-diacylglycerol cholinephosphotransferase(gene name synonym)|uniprotkb:N1218(orf name)|uniprotkb:N1867(orf name)|uniprotkb:YNL130C(locus name)|uniprotkb:CPT1(gene name)|psi-mi:CPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase CPT1(gene name synonym) psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343708|imex:IM-14275-2707 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005074|refseq:NP_014269.4|dip:DIP-7848N|mint:P17898|ensemblfungi:YNL130C(gene)|ensemblfungi:YNL130C_mRNA(transcript)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006657"(CDP-choline pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213 refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:PsU8UELFPsbtbzOS6oBnXJAuk/A559292 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 intact-crc:F5CF7E658EB34155|rigid:oGaSw9K9omT3MOgn64Kb7vkxStk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:P38264 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343719|imex:IM-14275-2708 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 intact-crc:6536CDC3686CE9A9|rigid:7+V0l+B48EoxTpcxuMNseEkBOy8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38353 uniprotkb:Q05359 intact:EBI-18175|uniprotkb:D6VQS8|ensemblfungi:YBR283C intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A psi-mi:ssh1_yeast(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:Ssh1 complex subunit alpha(gene name synonym)|uniprotkb:Ssh1 complex subunit SSH1(gene name synonym)|uniprotkb:YBR2020(orf name)|uniprotkb:YBR283C(locus name) psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343730|imex:IM-14275-2709 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009842.1|sgd:S000000487|ensemblfungi:YBR283C(gene)|ensemblfungi:YBR283C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:2WW9|rcsb pdb:2WWA|dip:DIP-4962N|mint:P38353 refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:48267EEA3E0191BD - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:76wvZIdv7W5BQn6wI+sHOGQAyuc559292 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 intact-crc:1D7AACDC57C317B6|rigid:DAOUFkRyvCP2XtNd8TjpQDpuTxQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:P38694 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-24511|uniprotkb:D3DKY6|ensemblfungi:YHR039C psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:msc7_yeast(display_long)|uniprotkb:MSC7(gene name)|psi-mi:MSC7(display_short)|uniprotkb:Meiotic sister-chromatid recombination protein 7(gene name synonym)|uniprotkb:YHR039C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343741|imex:IM-14275-2710 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_011904.1|sgd:S000001081|dip:DIP-1878N|mint:P38694|ensemblfungi:YHR039C(gene)|ensemblfungi:YHR039C_mRNA(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007131"(reciprocal meiotic recombination)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:p2xtb6/xYI/jfPNtO6JRZs+5t6I559292 intact-crc:99A449C352A7BC44|rigid:d0Inv4QUmyLxOP0YK3F6h13zKVU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:P38902 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-15806|ensemblfungi:YOL005C|uniprotkb:D6W262 psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:rpb11_yeast(display_long)|uniprotkb:YOL005C(locus name)|uniprotkb:RPB11(gene name)|psi-mi:RPB11(display_short)|uniprotkb:DNA-directed RNA polymerase II 13.6 kDa polypeptide(gene name synonym)|uniprotkb:B13.6(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343752|imex:IM-14275-2711 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_014638.1|sgd:S000005365|ensemblfungi:YOL005C_mRNA(transcript)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR036603|interpro:IPR037685|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|ensemblfungi:YOL005C(gene)|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:4A93|rcsb pdb:5SVA|rcsb pdb:4BBR|rcsb pdb:5U5Q|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4V1M|rcsb pdb:6BLP|rcsb pdb:6UQ3|rcsb pdb:6BM2|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:7KEF|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|dip:DIP-937N|mint:P38902 psi-mi:"MI:0469"(intact) - crc64:A98D109C5FF8E356 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:C9ofD255l4o5MjuGiqUVPfY4FdQ559292 intact-crc:E43A66D8FCDE8132|rigid:fn+U53/z19nfZsYIL+uB82FXQeU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:P40350 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-2470|uniprotkb:D6W3E3|ensemblfungi:YPL227C psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:alg5_yeast(display_long)|uniprotkb:ALG5(gene name)|psi-mi:ALG5(display_short)|uniprotkb:YPL227C(locus name)|uniprotkb:P1437(orf name)|uniprotkb:Asparagine-linked glycosylation protein 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343763|imex:IM-14275-2712 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_015097.1|sgd:S000006148|dip:DIP-5651N|mint:P40350|ensemblfungi:YPL227C(gene)|ensemblfungi:YPL227C_mRNA(transcript)|go:"GO:0004581"(dolichyl-phosphate beta-glucosyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR035518|reactome:R-SCE-480985 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:aKi97cbwqo7kNWhtRyzG3UOLH4U559292 intact-crc:8FB83C35B7499A84|rigid:LEpCDh+lD5JRm7h4uqb05QLfOjA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40471 uniprotkb:Q05359 intact:EBI-25213|uniprotkb:D6VVG3|ensemblfungi:YIL124W intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A psi-mi:ayr1_yeast(display_long)|uniprotkb:AYR1(gene name)|psi-mi:AYR1(display_short)|uniprotkb:Acylglycerone-phosphate reductase(gene name synonym)|uniprotkb:1-acyl DHAP reductase(gene name synonym)|uniprotkb:Acyl/alkyl DHAP reductase(gene name synonym)|uniprotkb:GBG1(gene name synonym)|uniprotkb:Triacylglycerol lipase AYR1(gene name synonym)|uniprotkb:YIL124W(locus name) psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343774|imex:IM-14275-2713 author score:99.34 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001386|refseq:NP_012142.3|mint:P40471|dip:DIP-4614N|ensemblfungi:YIL124W(gene)|ensemblfungi:YIL124W_mRNA(transcript)|go:"GO:0000140"(acylglycerone-phosphate reductase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0102566"(1-acyl dihydroxyacetone phosphate reductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291 refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:B614C0E0B1FB0CE0 - figure legend:tables S3 and S4|author-confidence:99.34|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WE4RmSXARj683MNUEsYGLis36Xo559292 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 intact-crc:E8F4CA810355C39A|rigid:hb+Fra4oEIN7Cf/NrA486YUlCf4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:P40540 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343785|imex:IM-14275-2714 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) - crc64:6DBEEEE7722203B0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 intact-crc:96BE6955B3EF6C09|rigid:igsaFeOzsWup3/Vbfhd5UoddArE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:P43621 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-4876|uniprotkb:D6VTT4|ensemblfungi:YFR051C psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:copd_yeast(display_long)|uniprotkb:RET2(gene name)|psi-mi:RET2(display_short)|uniprotkb:YFR051C(locus name)|uniprotkb:Delta-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343796|imex:IM-14275-2715 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 sgd:S000001947|refseq:NP_116709.3|dip:DIP-5255N|mint:P43621|ensemblfungi:YFR051C(gene)|ensemblfungi:YFR051C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|rcsb pdb:5FJW|rcsb pdb:5FJX|rcsb pdb:5FJZ|rcsb pdb:5FK0|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - crc64:AA730F046655EE5A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:auvjuT8ffm1R4P3mRKEIWAsynW0559292 intact-crc:71CAFBF215142B57|rigid:Mxv6sgoPnkC6uX6V5pZNLLSBhs8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53337 uniprotkb:Q05359 intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343807|imex:IM-14275-2716 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 intact-crc:7244E006FFAA4BD8|rigid:AtfNIe+OVzx84T+BjkIRs3vosi8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:P54837 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343818|imex:IM-14275-2717 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:77F6C721FF8278AC|rigid:V5KQkDduN7O4IuduxAjK7NTdcJI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:Q03554 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-2057821|uniprotkb:D6W0B9|ensemblfungi:YMR292W psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:got1_yeast(display_long)|uniprotkb:GOT1(gene name)|psi-mi:GOT1(display_short)|uniprotkb:Golgi transport protein 1(gene name synonym)|uniprotkb:YMR292W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343829|imex:IM-14275-2718 author score:99.37 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_014020.1|sgd:S000004906|dip:DIP-8271N|mint:Q03554|ensemblfungi:YMR292W(gene)|ensemblfungi:YMR292W_mRNA(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.37|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:wO79x4uMwWaL6v00y28srGL561E559292 intact-crc:B3100C7729D5794C|rigid:+4HYnsU4BDNLa4u8li3awxnqbqU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:Q05359 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343840|imex:IM-14275-2719 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 intact-crc:55B0C1EA94F0E202|rigid:BC4mZGXZHM+XfJwU2Kz2uvh8FIA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:Q06144 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343851|imex:IM-14275-2720 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:2F474503CAB7C195 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 intact-crc:16194AFCF203E27A|rigid:GpLgXXxTyiyQ+T4FCt6hreac7DM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:Q08926 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-2044051|uniprotkb:D6W3I3|ensemblfungi:YPL186C psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:uip4_yeast(display_long)|uniprotkb:YPL186C(locus name)|uniprotkb:UIP4(gene name)|psi-mi:UIP4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343862|imex:IM-14275-2721 author score:99.34 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 sgd:S000006107|refseq:NP_015138.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold)|mint:Q08926|ensemblfungi:YPL186C(gene)|ensemblfungi:YPL186C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.34|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:jZmXJYN6MQPlKDZXQnkU2tSI7vM559292 intact-crc:585F98AE6A65AD47|rigid:u2j4ASVEkNOnDkA1xr796kUGaGA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12450 uniprotkb:Q05359 intact:EBI-6598|uniprotkb:D6W282|ensemblfungi:YOR016C intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A psi-mi:erp4_yeast(display_long)|uniprotkb:ERP4(gene name)|psi-mi:ERP4(display_short)|uniprotkb:YOR016C(locus name) psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343873|imex:IM-14275-2722 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014659.1|sgd:S000005542|mint:Q12450|dip:DIP-7868N|ensemblfungi:YOR016C(gene)|ensemblfungi:YOR016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|reactome:R-SCE-6811434 refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:An7as6LjEDUYrLvEbua3xSL6bEk559292 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 intact-crc:64A4041DDFDC4EE3|rigid:BG6cJwNGV5kWmW1jjq3rQO9Ici8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99287 uniprotkb:Q05359 intact:EBI-37523|uniprotkb:D6W2M3|ensemblfungi:YOR165W intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A psi-mi:sey1_yeast(display_long)|uniprotkb:SEY1(gene name)|psi-mi:SEY1(display_short)|uniprotkb:YOR165W(locus name)|uniprotkb:Synthetic enhancer of YOP1 protein(gene name synonym)|uniprotkb:O3590(orf name) psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343884|imex:IM-14275-2723 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014808.1|sgd:S000005691|dip:DIP-49373N|mint:Q99287|ensemblfungi:YOR165W(gene)|ensemblfungi:YOR165W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0061024"(membrane organization)|go:"GO:0071944"(cell periphery)|interpro:IPR008803(Root hair defective 3 GTP-binding)|interpro:IPR027417|interpro:IPR030386 refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:DEC0C9EC3AB172DF - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zFsgalfyUvAuuV51vChJjraiQmI559292 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 intact-crc:45F6E2906DD48CD1|rigid:0yCsX5Dn5yyI3Dwy9OVoBavoILE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25847 uniprotkb:Q05471 intact:EBI-11352|uniprotkb:Q12423|ensemblfungi:YOL090W|uniprotkb:D6W1X8 intact:EBI-22102|uniprotkb:D6VSW6|ensemblfungi:YDR334W psi-mi:msh2_yeast(display_long)|uniprotkb:MSH2(gene name)|psi-mi:MSH2(display_short)|uniprotkb:YOL090W(locus name)|uniprotkb:O0935(orf name)|uniprotkb:MutS protein homolog 2(gene name synonym) psi-mi:swr1_yeast(display_long)|uniprotkb:Swi2/Snf2-related 1(gene name synonym)|uniprotkb:SWR1(gene name)|psi-mi:SWR1(display_short)|uniprotkb:YDR334W(locus name)|uniprotkb:D9651.6(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343895|imex:IM-14275-2724 author score:99.36 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOL090W(gene)|ensemblfungi:YOL090W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000735"(removal of nonhomologous ends)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0006312"(mitotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043111"(replication fork arrest)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR032642|interpro:IPR036187|interpro:IPR036678|reactome:R-SCE-5358565|reactome:R-SCE-5358606|go:"GO:0032300"(mismatch repair complex)|refseq:NP_014551.1|sgd:S000005450|mint:P25847|dip:DIP-2415N refseq:NP_010621.1|sgd:S000002742|dip:DIP-2845N|ensemblfungi:YDR334W(gene)|ensemblfungi:YDR334W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0043486"(histone exchange)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR027417|interpro:IPR038718|rcsb pdb:4M6B|rcsb pdb:5I9E|rcsb pdb:6GEJ|rcsb pdb:6GEN|mint:Q05471 psi-mi:"MI:0469"(intact) crc64:43FFD8A640138AE4 crc64:156E3BB5978905C8 figure legend:tables S3 and S4|author-confidence:99.36|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:PNwekSiaI58qR+dPZZQW5UNRJ+4559292 rogid:Lo9+YZNnIZlJ8/Tq7XW3lDjUsBQ559292 intact-crc:6BDAC71495ABF311|rigid:1465aspo/vTTTeVUtFROuXm1xVw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05515 uniprotkb:Q03370 intact:EBI-38400|uniprotkb:D6VSX6|ensemblfungi:YDR346C intact:EBI-36170|uniprotkb:D6VTA2|ensemblfungi:YDR479C psi-mi:svf1_yeast(display_long)|uniprotkb:SVF1(gene name)|psi-mi:SVF1(display_short)|uniprotkb:SGI1(gene name synonym)|uniprotkb:YDR346C(locus name) psi-mi:pex29_yeast(display_long)|uniprotkb:PEX29(gene name)|psi-mi:PEX29(display_short)|uniprotkb:Peroxin-29(gene name synonym)|uniprotkb:YDR479C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343906|imex:IM-14275-2725 author score:99.34 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002754|refseq:NP_010633.3|mint:Q05515|dip:DIP-5243N|ensemblfungi:YDR346C(gene)|ensemblfungi:YDR346C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034599"(cellular response to oxidative stress)|interpro:IPR013931(Oxidative stress survival, Svf1-like)|interpro:IPR033394 refseq:NP_010767.1|sgd:S000002887|mint:Q03370|dip:DIP-5175N|ensemblfungi:YDR479C(gene)|ensemblfungi:YDR479C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032581"(ER-dependent peroxisome organization)|interpro:IPR010482(Integral peroxisomal membrane peroxin) psi-mi:"MI:0469"(intact) crc64:926A28FE140F87A5 crc64:C2EB849C36FB69EB figure legend:tables S3 and S4|author-confidence:99.34|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K9DLW9y+JFX3NTUKWKHVb/YpPVg559292 rogid:XirbTI20sgYx5DDsELcnS9RLxMw559292 intact-crc:9A06CA76CF62E2D5|rigid:iLIYIkSWALrbeVUTtUoohtLiL2c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05521 uniprotkb:P09620 intact:EBI-2054360|uniprotkb:D6VSR4|ensemblfungi:YDR284C intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:dpp1_yeast(display_long)|uniprotkb:ZRG1(gene name synonym)|uniprotkb:Phosphatidate phosphatase(gene name synonym)|uniprotkb:YDR284C(locus name)|uniprotkb:DPP1(gene name)|psi-mi:DPP1(display_short)|uniprotkb:Lysophosphatidate phosphatase(gene name synonym) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343917|imex:IM-14275-2726 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010570.1|sgd:S000002692|dip:DIP-8807N|mint:Q05521|ensemblfungi:YDR284C(gene)|ensemblfungi:YDR284C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000810"(diacylglycerol diphosphate phosphatase activity)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042577"(lipid phosphatase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR043216|reactome:R-SCE-1660661|reactome:R-SCE-2029485|reactome:R-SCE-419408 ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Hj9zgQNj43XlykGFSKPcXJ28Lqg559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:72861217CBE27C93|rigid:rnkA7kv2NKi0Egvx04BeB0+vYvA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05521 uniprotkb:P38310 intact:EBI-2054360|uniprotkb:D6VSR4|ensemblfungi:YDR284C intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:dpp1_yeast(display_long)|uniprotkb:ZRG1(gene name synonym)|uniprotkb:Phosphatidate phosphatase(gene name synonym)|uniprotkb:YDR284C(locus name)|uniprotkb:DPP1(gene name)|psi-mi:DPP1(display_short)|uniprotkb:Lysophosphatidate phosphatase(gene name synonym) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343928|imex:IM-14275-2727 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010570.1|sgd:S000002692|dip:DIP-8807N|mint:Q05521|ensemblfungi:YDR284C(gene)|ensemblfungi:YDR284C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000810"(diacylglycerol diphosphate phosphatase activity)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042577"(lipid phosphatase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR043216|reactome:R-SCE-1660661|reactome:R-SCE-2029485|reactome:R-SCE-419408 refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) psi-mi:"MI:0469"(intact) - crc64:7B4E620ABC39A053 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Hj9zgQNj43XlykGFSKPcXJ28Lqg559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 intact-crc:AB4F1B476533BA14|rigid:J9heUz5+BWzS9V3qbURsJXvMYbk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38929 uniprotkb:Q05521 intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W intact:EBI-2054360|uniprotkb:D6VSR4|ensemblfungi:YDR284C psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:dpp1_yeast(display_long)|uniprotkb:ZRG1(gene name synonym)|uniprotkb:Phosphatidate phosphatase(gene name synonym)|uniprotkb:YDR284C(locus name)|uniprotkb:DPP1(gene name)|psi-mi:DPP1(display_short)|uniprotkb:Lysophosphatidate phosphatase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343939|imex:IM-14275-2728 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 refseq:NP_010570.1|sgd:S000002692|dip:DIP-8807N|mint:Q05521|ensemblfungi:YDR284C(gene)|ensemblfungi:YDR284C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000810"(diacylglycerol diphosphate phosphatase activity)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042577"(lipid phosphatase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR043216|reactome:R-SCE-1660661|reactome:R-SCE-2029485|reactome:R-SCE-419408 psi-mi:"MI:0469"(intact) crc64:5BD9ECFF8508F396 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 rogid:Hj9zgQNj43XlykGFSKPcXJ28Lqg559292 intact-crc:8949D1663E6DFBD1|rigid:p9+xwJ9bOEbH4DtNkE3gkR/XIpc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05521 uniprotkb:P39968 intact:EBI-2054360|uniprotkb:D6VSR4|ensemblfungi:YDR284C intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W psi-mi:dpp1_yeast(display_long)|uniprotkb:ZRG1(gene name synonym)|uniprotkb:Phosphatidate phosphatase(gene name synonym)|uniprotkb:YDR284C(locus name)|uniprotkb:DPP1(gene name)|psi-mi:DPP1(display_short)|uniprotkb:Lysophosphatidate phosphatase(gene name synonym) psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343950|imex:IM-14275-2729 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010570.1|sgd:S000002692|dip:DIP-8807N|mint:Q05521|ensemblfungi:YDR284C(gene)|ensemblfungi:YDR284C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000810"(diacylglycerol diphosphate phosphatase activity)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042577"(lipid phosphatase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR043216|reactome:R-SCE-1660661|reactome:R-SCE-2029485|reactome:R-SCE-419408 sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N psi-mi:"MI:0469"(intact) - crc64:B2E75774B47E5933 figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Hj9zgQNj43XlykGFSKPcXJ28Lqg559292 rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292 intact-crc:C8333E039051814F|rigid:cNazBxlgylPGTHVT4NjoGuJC2/g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41807 uniprotkb:Q05521 intact:EBI-20281|uniprotkb:D6W446|ensemblfungi:YPR036W intact:EBI-2054360|uniprotkb:D6VSR4|ensemblfungi:YDR284C psi-mi:vath_yeast(display_long)|uniprotkb:YP3085.02(orf name)|uniprotkb:VMA13(gene name)|psi-mi:VMA13(display_short)|uniprotkb:CLS11(gene name synonym)|uniprotkb:YPR036W(locus name)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 54 kDa subunit(gene name synonym) psi-mi:dpp1_yeast(display_long)|uniprotkb:ZRG1(gene name synonym)|uniprotkb:Phosphatidate phosphatase(gene name synonym)|uniprotkb:YDR284C(locus name)|uniprotkb:DPP1(gene name)|psi-mi:DPP1(display_short)|uniprotkb:Lysophosphatidate phosphatase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343961|imex:IM-14275-2730 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015361.1|sgd:S000006240|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|rcsb pdb:1HO8|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YPR036W(gene)|ensemblfungi:YPR036W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|dip:DIP-6640N|mint:P41807 refseq:NP_010570.1|sgd:S000002692|dip:DIP-8807N|mint:Q05521|ensemblfungi:YDR284C(gene)|ensemblfungi:YDR284C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000810"(diacylglycerol diphosphate phosphatase activity)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042577"(lipid phosphatase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR043216|reactome:R-SCE-1660661|reactome:R-SCE-2029485|reactome:R-SCE-419408 psi-mi:"MI:0469"(intact) crc64:54131FF9C2C87594 - figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kEXWvOsnTk0WdgGOny+mufz4lTo559292 rogid:Hj9zgQNj43XlykGFSKPcXJ28Lqg559292 intact-crc:4B5CDCBD757A074D|rigid:RfaW2u3loU43n3DJ50r8Ff+cuPw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05521 uniprotkb:Q05521 intact:EBI-2054360|uniprotkb:D6VSR4|ensemblfungi:YDR284C intact:EBI-2054360|uniprotkb:D6VSR4|ensemblfungi:YDR284C psi-mi:dpp1_yeast(display_long)|uniprotkb:ZRG1(gene name synonym)|uniprotkb:Phosphatidate phosphatase(gene name synonym)|uniprotkb:YDR284C(locus name)|uniprotkb:DPP1(gene name)|psi-mi:DPP1(display_short)|uniprotkb:Lysophosphatidate phosphatase(gene name synonym) psi-mi:dpp1_yeast(display_long)|uniprotkb:ZRG1(gene name synonym)|uniprotkb:Phosphatidate phosphatase(gene name synonym)|uniprotkb:YDR284C(locus name)|uniprotkb:DPP1(gene name)|psi-mi:DPP1(display_short)|uniprotkb:Lysophosphatidate phosphatase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343972|imex:IM-14275-2731 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010570.1|sgd:S000002692|dip:DIP-8807N|mint:Q05521|ensemblfungi:YDR284C(gene)|ensemblfungi:YDR284C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000810"(diacylglycerol diphosphate phosphatase activity)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042577"(lipid phosphatase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR043216|reactome:R-SCE-1660661|reactome:R-SCE-2029485|reactome:R-SCE-419408 refseq:NP_010570.1|sgd:S000002692|dip:DIP-8807N|mint:Q05521|ensemblfungi:YDR284C(gene)|ensemblfungi:YDR284C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000810"(diacylglycerol diphosphate phosphatase activity)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042577"(lipid phosphatase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR043216|reactome:R-SCE-1660661|reactome:R-SCE-2029485|reactome:R-SCE-419408 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Hj9zgQNj43XlykGFSKPcXJ28Lqg559292 rogid:Hj9zgQNj43XlykGFSKPcXJ28Lqg559292 intact-crc:2F453059879A20CB|rigid:ey0f688vAQwsinujA7MQ/ThW0wM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40470 uniprotkb:Q05543 intact:EBI-2084979|uniprotkb:D6VVG0|ensemblfungi:YIL127C intact:EBI-35018|uniprotkb:D6VSR9|ensemblfungi:YDR289C psi-mi:rrt14_yeast(display_long)|uniprotkb:YIL127C(locus name)|uniprotkb:RRT14(gene name)|psi-mi:RRT14(display_short) psi-mi:rt103_yeast(display_long)|uniprotkb:RTT103(gene name)|psi-mi:RTT103(display_short)|uniprotkb:YDR289C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343983|imex:IM-14275-2732 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001389|refseq:NP_012139.1|interpro:IPR031404|mint:P40470|ensemblfungi:YIL127C(gene)|ensemblfungi:YIL127C_mRNA(transcript)|go:"GO:0005730"(nucleolus)|rcsb pdb:5WLC|rcsb pdb:6LQP|rcsb pdb:6LQS|rcsb pdb:6LQU|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:7AJT refseq:NP_010575.1|sgd:S000002697|mint:Q05543|dip:DIP-2583N|ensemblfungi:YDR289C(gene)|ensemblfungi:YDR289C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|rcsb pdb:2KM4|rcsb pdb:2L0I|rcsb pdb:5M48|rcsb pdb:5WOZ|reactome:R-SCE-6807505 psi-mi:"MI:0469"(intact) - crc64:08D37739466E3010 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Jv1tHpy0kCIv7gE6JY8kpmHm3UY559292 rogid:jsnGt1FLW8sTewVH7dwY+cplV7Q559292 intact-crc:49F03FB5C6973DB1|rigid:viNSTAOXxSmfjl9koJGnlvPmHo0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08235 uniprotkb:Q05543 intact:EBI-3775|uniprotkb:D6W1Z1|ensemblfungi:YOL077C intact:EBI-35018|uniprotkb:D6VSR9|ensemblfungi:YDR289C psi-mi:brx1_yeast(display_long)|uniprotkb:YOL077C(locus name)|uniprotkb:BRX1(gene name)|psi-mi:BRX1(display_short) psi-mi:rt103_yeast(display_long)|uniprotkb:RTT103(gene name)|psi-mi:RTT103(display_short)|uniprotkb:YDR289C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6343994|imex:IM-14275-2733 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014565.2|sgd:S000005437|dip:DIP-6317N|mint:Q08235|ensemblfungi:YOL077C(gene)|ensemblfungi:YOL077C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000464"("endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000465"("exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR007109(Brix)|interpro:IPR026532|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5 refseq:NP_010575.1|sgd:S000002697|mint:Q05543|dip:DIP-2583N|ensemblfungi:YDR289C(gene)|ensemblfungi:YDR289C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|rcsb pdb:2KM4|rcsb pdb:2L0I|rcsb pdb:5M48|rcsb pdb:5WOZ|reactome:R-SCE-6807505 psi-mi:"MI:0469"(intact) crc64:31466853EF0E7301 crc64:08D37739466E3010 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mPR6HWKwM6RNCRE/vezsYlCmEGY559292 rogid:jsnGt1FLW8sTewVH7dwY+cplV7Q559292 intact-crc:31B6A530F39EFE43|rigid:YLkD/16DHjhzbFRZkrA8zemHKsY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05568 uniprotkb:P32445 intact:EBI-13194|uniprotkb:E9P8T2|ensemblfungi:YDR265W|uniprotkb:D6VSP9 intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A psi-mi:pex10_yeast(display_long)|uniprotkb:PAS4(gene name synonym)|uniprotkb:YDR265W(locus name)|uniprotkb:D9954.8(orf name)|uniprotkb:PEX10(gene name)|psi-mi:PEX10(display_short)|uniprotkb:Peroxin-10(gene name synonym)|uniprotkb:Peroxisome assembly protein 10(gene name synonym)|uniprotkb:Peroxisomal biogenesis factor 10(gene name synonym) psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344005|imex:IM-14275-2734 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010551.1|sgd:S000002673|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|ensemblfungi:YDR265W(gene)|ensemblfungi:YDR265W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR006845(Pex, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-SCE-8866654|reactome:R-SCE-9033241|mint:Q05568|dip:DIP-7566N refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 psi-mi:"MI:0469"(intact) - crc64:9F913C2FC9EF6E82 figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pA1kuOZK1fCAf6QW5gth+fSVtdo559292 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 intact-crc:57245D70A93ABFD0|rigid:Ld2vd6w9sZC/GhTD2KWR9Yn3lLA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12462 uniprotkb:Q05568 intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C intact:EBI-13194|uniprotkb:E9P8T2|ensemblfungi:YDR265W|uniprotkb:D6VSP9 psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:pex10_yeast(display_long)|uniprotkb:PAS4(gene name synonym)|uniprotkb:YDR265W(locus name)|uniprotkb:D9954.8(orf name)|uniprotkb:PEX10(gene name)|psi-mi:PEX10(display_short)|uniprotkb:Peroxin-10(gene name synonym)|uniprotkb:Peroxisome assembly protein 10(gene name synonym)|uniprotkb:Peroxisomal biogenesis factor 10(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344016|imex:IM-14275-2735 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) refseq:NP_010551.1|sgd:S000002673|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|ensemblfungi:YDR265W(gene)|ensemblfungi:YDR265W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR006845(Pex, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-SCE-8866654|reactome:R-SCE-9033241|mint:Q05568|dip:DIP-7566N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 rogid:pA1kuOZK1fCAf6QW5gth+fSVtdo559292 intact-crc:BEF69F484EFF7357|rigid:QMxcSaTfN4whm1ca9FRGh0WIVuY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50079 uniprotkb:Q05584 intact:EBI-23505|uniprotkb:D6VV05|ensemblfungi:YGR223C intact:EBI-7672|uniprotkb:D6VSQ4|uniprotkb:E9P8T0|ensemblfungi:YDR272W psi-mi:hsv2_yeast(display_long)|uniprotkb:G8530(orf name)|uniprotkb:YGR223C(locus name)|uniprotkb:HSV2(gene name)|psi-mi:HSV2(display_short) psi-mi:glo2_yeast(display_long)|uniprotkb:GLO2(gene name)|psi-mi:GLO2(display_short)|uniprotkb:YDR272W(locus name)|uniprotkb:D9954.5(orf name)|uniprotkb:Glyoxalase II(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344027|imex:IM-14275-2736 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011739.1|sgd:S000003455|dip:DIP-5556N|mint:P50079|ensemblfungi:YGR223C(gene)|ensemblfungi:YGR223C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006497"(protein lipidation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-SCE-1632852 interpro:IPR036866|sgd:S000002680|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR032282|refseq:NP_010558.3|mint:Q05584|interpro:IPR035680|ensemblfungi:YDR272W(gene)|ensemblfungi:YDR272W_mRNA(transcript)|go:"GO:0004416"(hydroxyacylglutathione hydrolase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019243"(methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) crc64:A4287FAB80AA68DF - figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ry4AOefJ9FKdASKObhv/F29TfxQ559292 rogid:E603Djz4bECCMxONjGGRURfAwGw559292 intact-crc:C55B2A2CA1457A24|rigid:fLaMQX4ig71UuxRgdZT9QtxZHuQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05611 uniprotkb:Q8TGJ2 intact:EBI-37177|uniprotkb:D6VSQ6|ensemblfungi:YDR275W intact:EBI-2047109|uniprotkb:D6W1Q1|ensemblfungi:YNR075C-A psi-mi:bsc2_yeast(display_long)|uniprotkb:BSC2(gene name)|psi-mi:BSC2(display_short)|uniprotkb:YDR275W(locus name) psi-mi:yn075_yeast(display_long)|uniprotkb:YNR075C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344038|imex:IM-14275-2737 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002683|refseq:NP_010561.1|mint:Q05611|dip:DIP-5218N|ensemblfungi:YDR275W(gene)|ensemblfungi:YDR275W_mRNA(transcript)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane) sgd:S000028706|refseq:NP_878159.3|mint:Q8TGJ2|ensemblfungi:YNR075C-A(gene)|ensemblfungi:YNR075C-A_mRNA(transcript) psi-mi:"MI:0469"(intact) crc64:9987EE269A88CB12 - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cxo79tjwlg/5V66JBjB+sWqHkmI559292 rogid:a2YkRms9fcm6XZTy1Q74gRGCXPY559292 intact-crc:C502C05A55ECE045|rigid:qH7glQFwu/yYoXC2tsesQWkGM4E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04049 uniprotkb:Q05672 intact:EBI-36214|uniprotkb:D6VT49|ensemblfungi:YDR419W intact:EBI-36115|uniprotkb:D6VRG4|uniprotkb:Q06896|uniprotkb:Q07619|uniprotkb:Q870H2|ensemblfungi:YDL189W psi-mi:polh_yeast(display_long)|uniprotkb:RAD30(gene name)|psi-mi:RAD30(display_short)|uniprotkb:DBH1(gene name synonym)|uniprotkb:YDR419W(locus name)|uniprotkb:Radiation-sensitive protein 30(gene name synonym) psi-mi:rbs1_yeast(display_long)|uniprotkb:RBS1(gene name)|psi-mi:RBS1(display_short)|uniprotkb:D1266(orf name)|uniprotkb:YDL189W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344049|imex:IM-14275-2738 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002827|refseq:NP_010707.3|mint:Q04049|dip:DIP-6500N|ensemblfungi:YDR419W(gene)|ensemblfungi:YDR419W_mRNA(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0070987"(error-free translesion synthesis)|interpro:IPR001126(UMUC-like DNA-repair protein)|interpro:IPR036775|interpro:IPR041298|interpro:IPR043128|interpro:IPR043502|rcsb pdb:1JIH|rcsb pdb:2R8J|rcsb pdb:2R8K|rcsb pdb:2WTF|rcsb pdb:2XGP|rcsb pdb:2XGQ|rcsb pdb:3MFH|rcsb pdb:3MFI|rcsb pdb:3OHA|rcsb pdb:3OHB|rcsb pdb:5VTP|reactome:R-SCE-110320|reactome:R-SCE-5656169 refseq:NP_010092.2|sgd:S000002348|mint:Q05672|dip:DIP-2980N|ensemblfungi:YDL189W(gene)|ensemblfungi:YDL189W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:1990115"(RNA polymerase III assembly)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR036867 psi-mi:"MI:0469"(intact) crc64:CFB1A9FBC8AFE39B - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UezH5s3d7XqG3y3LEglWvRzgzCc559292 rogid:V33VbkR395Vk+AB8eZE/dbpzfKU559292 intact-crc:387760A3A46626E0|rigid:vUrYhaWe/moOlzGiokDUelMXL18 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08281 uniprotkb:Q05672 intact:EBI-2047093|uniprotkb:D6W1T1|uniprotkb:Q92271|ensemblfungi:YOL138C intact:EBI-36115|uniprotkb:D6VRG4|uniprotkb:Q06896|uniprotkb:Q07619|uniprotkb:Q870H2|ensemblfungi:YDL189W psi-mi:rtc1_yeast(display_long)|uniprotkb:RTC1(gene name)|psi-mi:RTC1(display_short)|uniprotkb:SEA2(gene name synonym)|uniprotkb:SEH-associated protein 2(gene name synonym)|uniprotkb:YOL138C(locus name) psi-mi:rbs1_yeast(display_long)|uniprotkb:RBS1(gene name)|psi-mi:RBS1(display_short)|uniprotkb:D1266(orf name)|uniprotkb:YDL189W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344060|imex:IM-14275-2739 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR037590|refseq:NP_014503.2|sgd:S000005498|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q08281|interpro:IPR036322|ensemblfungi:YOL138C(gene)|ensemblfungi:YOL138C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0035859"(Seh1-associated complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0097042"(extrinsic component of fungal-type vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling) refseq:NP_010092.2|sgd:S000002348|mint:Q05672|dip:DIP-2980N|ensemblfungi:YDL189W(gene)|ensemblfungi:YDL189W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:1990115"(RNA polymerase III assembly)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR036867 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3k6vZ9TxDj/BcLSmeJdAg45Ri14559292 rogid:V33VbkR395Vk+AB8eZE/dbpzfKU559292 intact-crc:B5DD29E88FBDEC60|rigid:PsV2n6xGTTfYzyu3u73VIVBJX3I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05812 uniprotkb:Q05812 intact:EBI-33150|uniprotkb:Q7LIF4|uniprotkb:D6VYL9|ensemblfungi:YLR219W intact:EBI-33150|uniprotkb:Q7LIF4|uniprotkb:D6VYL9|ensemblfungi:YLR219W psi-mi:msc3_yeast(display_long)|uniprotkb:MSC3(gene name)|psi-mi:MSC3(display_short)|uniprotkb:YLR219W(locus name) psi-mi:msc3_yeast(display_long)|uniprotkb:MSC3(gene name)|psi-mi:MSC3(display_short)|uniprotkb:YLR219W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344071|imex:IM-14275-2740 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004209|refseq:NP_013320.1|mint:Q05812|dip:DIP-6321N|ensemblfungi:YLR219W(gene)|ensemblfungi:YLR219W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007131"(reciprocal meiotic recombination) sgd:S000004209|refseq:NP_013320.1|mint:Q05812|dip:DIP-6321N|ensemblfungi:YLR219W(gene)|ensemblfungi:YLR219W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007131"(reciprocal meiotic recombination) psi-mi:"MI:0469"(intact) crc64:1962D638DB602B71 crc64:1962D638DB602B71 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:xS8zCG9eHY8V0vNstOwUuTcI3Ao559292 rogid:xS8zCG9eHY8V0vNstOwUuTcI3Ao559292 intact-crc:947AD7B63719C26E|rigid:Aer98Hsv83rP/bdGhWyJ0A/jujg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05919 uniprotkb:Q06815 intact:EBI-29972|uniprotkb:Q6B1J7|uniprotkb:D6VYZ7|ensemblfungi:YLR360W intact:EBI-33784|uniprotkb:D6W481|ensemblfungi:YPR079W psi-mi:vps38_yeast(display_long)|uniprotkb:VPS38(gene name)|psi-mi:VPS38(display_short)|uniprotkb:VPL17(gene name synonym)|uniprotkb:YLR360W(locus name)|uniprotkb:L8039.11(orf name) psi-mi:mrl1_yeast(display_long)|uniprotkb:YPR079W(locus name)|uniprotkb:MRL1(gene name)|psi-mi:MRL1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344082|imex:IM-14275-2741 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004352|refseq:NP_013464.3|dip:DIP-8809N|mint:Q05919|ensemblfungi:YLR360W(gene)|ensemblfungi:YLR360W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045324"(late endosome to vacuole transport)|interpro:IPR040939|rcsb pdb:5DFZ|reactome:R-SCE-1632852 refseq:NP_015404.1|sgd:S000006283|mint:Q06815|dip:DIP-2873N|ensemblfungi:YPR079W(gene)|ensemblfungi:YPR079W_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007034"(vacuolar transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR036607|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:70141E084D185015 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:J13HZljzRxl6p0wukZg3YXJn6+w559292 rogid:PFMxRfVBupoO0p3pb+BB5H2fidg559292 intact-crc:FF7B748C298BE401|rigid:tc4BDoXVSukEiWxJ3VwuwnWlSQ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05933 uniprotkb:P22137 intact:EBI-2764|uniprotkb:D6VZ07|ensemblfungi:YLR370C intact:EBI-4766|uniprotkb:D6VTU9|ensemblfungi:YGL206C psi-mi:arpc3_yeast(display_long)|uniprotkb:ARC18(gene name)|psi-mi:ARC18(display_short)|uniprotkb:YLR370C(locus name)|uniprotkb:L8039.15(orf name)|uniprotkb:Arp2/3 complex 21 kDa subunit(gene name synonym) psi-mi:clh_yeast(display_long)|uniprotkb:CHC1(gene name)|psi-mi:CHC1(display_short)|uniprotkb:YGL206C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344093|imex:IM-14275-2742 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004362|refseq:NP_013474.3|dip:DIP-2218N|mint:Q05933|ensemblfungi:YLR370C(gene)|ensemblfungi:YLR370C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR007204(ARP2/3 complex, 21 kDa p21-Arc subunit)|interpro:IPR036753|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 refseq:NP_011309.1|sgd:S000003174|dip:DIP-2279N|mint:P22137|ensemblfungi:YGL206C(gene)|ensemblfungi:YGL206C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0071439"(clathrin complex)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-432720|reactome:R-SCE-437239|reactome:R-SCE-8856828|reactome:R-SCE-8866427|reactome:R-SCE-8964038 psi-mi:"MI:0469"(intact) crc64:456EABC2B9CC4860 crc64:622F3083DF2FE315 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Fj4cwULcw1TK5uS1lJczcNc5gns559292 rogid:SAN6H3nVFozXZyTiRLaljMcIKIA559292 intact-crc:AD06ACC627482608|rigid:7a2l2simhbNOxZUVpXatEWGrm0I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33204 uniprotkb:Q05933 intact:EBI-2757|uniprotkb:D6VXS3|ensemblfungi:YKL013C intact:EBI-2764|uniprotkb:D6VZ07|ensemblfungi:YLR370C psi-mi:arpc4_yeast(display_long)|uniprotkb:ARC19(gene name)|psi-mi:ARC19(display_short)|uniprotkb:YKL013C(locus name)|uniprotkb:YKL166(orf name)|uniprotkb:Arp2/3 complex 20 kDa(gene name synonym) psi-mi:arpc3_yeast(display_long)|uniprotkb:ARC18(gene name)|psi-mi:ARC18(display_short)|uniprotkb:YLR370C(locus name)|uniprotkb:L8039.15(orf name)|uniprotkb:Arp2/3 complex 21 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344104|imex:IM-14275-2743 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012912.1|sgd:S000001496|dip:DIP-1819N|mint:P33204|ensemblfungi:YKL013C(gene)|ensemblfungi:YKL013C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 sgd:S000004362|refseq:NP_013474.3|dip:DIP-2218N|mint:Q05933|ensemblfungi:YLR370C(gene)|ensemblfungi:YLR370C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR007204(ARP2/3 complex, 21 kDa p21-Arc subunit)|interpro:IPR036753|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:B80CBD6642E39C1C crc64:456EABC2B9CC4860 figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wscMsqBK/3Rsah+2vbE3REyYhhg559292 rogid:Fj4cwULcw1TK5uS1lJczcNc5gns559292 intact-crc:4ED5CBE58428C755|rigid:i+pOj4dbEkUs/foPqVWoJPsn4vs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37370 uniprotkb:Q05933 intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C intact:EBI-2764|uniprotkb:D6VZ07|ensemblfungi:YLR370C psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:arpc3_yeast(display_long)|uniprotkb:ARC18(gene name)|psi-mi:ARC18(display_short)|uniprotkb:YLR370C(locus name)|uniprotkb:L8039.15(orf name)|uniprotkb:Arp2/3 complex 21 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344115|imex:IM-14275-2744 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370 sgd:S000004362|refseq:NP_013474.3|dip:DIP-2218N|mint:Q05933|ensemblfungi:YLR370C(gene)|ensemblfungi:YLR370C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR007204(ARP2/3 complex, 21 kDa p21-Arc subunit)|interpro:IPR036753|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:24C7522D5B1CA1C8 crc64:456EABC2B9CC4860 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 rogid:Fj4cwULcw1TK5uS1lJczcNc5gns559292 intact-crc:BFE4C00366D86518|rigid:9KrU/sQxJ25aWpk74b6E0XA0jK4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38328 uniprotkb:Q05933 intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C intact:EBI-2764|uniprotkb:D6VZ07|ensemblfungi:YLR370C psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:arpc3_yeast(display_long)|uniprotkb:ARC18(gene name)|psi-mi:ARC18(display_short)|uniprotkb:YLR370C(locus name)|uniprotkb:L8039.15(orf name)|uniprotkb:Arp2/3 complex 21 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344126|imex:IM-14275-2745 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 sgd:S000004362|refseq:NP_013474.3|dip:DIP-2218N|mint:Q05933|ensemblfungi:YLR370C(gene)|ensemblfungi:YLR370C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR007204(ARP2/3 complex, 21 kDa p21-Arc subunit)|interpro:IPR036753|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:D75C6BB8EC35EEDF crc64:456EABC2B9CC4860 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 rogid:Fj4cwULcw1TK5uS1lJczcNc5gns559292 intact-crc:3B0E37099B5C0228|rigid:cEDjeGmJnIRCeIQ+utQmGNddFp4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41811 uniprotkb:Q05933 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W intact:EBI-2764|uniprotkb:D6VZ07|ensemblfungi:YLR370C psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:arpc3_yeast(display_long)|uniprotkb:ARC18(gene name)|psi-mi:ARC18(display_short)|uniprotkb:YLR370C(locus name)|uniprotkb:L8039.15(orf name)|uniprotkb:Arp2/3 complex 21 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344137|imex:IM-14275-2746 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 sgd:S000004362|refseq:NP_013474.3|dip:DIP-2218N|mint:Q05933|ensemblfungi:YLR370C(gene)|ensemblfungi:YLR370C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR007204(ARP2/3 complex, 21 kDa p21-Arc subunit)|interpro:IPR036753|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:6A5E50BBEB02CB58 crc64:456EABC2B9CC4860 figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 rogid:Fj4cwULcw1TK5uS1lJczcNc5gns559292 intact-crc:0BDC94DDE6B6DFDD|rigid:vCkbZuCsOfMnXJ6If1ua3t+5KXU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05933 uniprotkb:Q04439 intact:EBI-2764|uniprotkb:D6VZ07|ensemblfungi:YLR370C intact:EBI-11687|ensemblfungi:YMR109W|uniprotkb:D6VZT2 psi-mi:arpc3_yeast(display_long)|uniprotkb:ARC18(gene name)|psi-mi:ARC18(display_short)|uniprotkb:YLR370C(locus name)|uniprotkb:L8039.15(orf name)|uniprotkb:Arp2/3 complex 21 kDa subunit(gene name synonym) psi-mi:myo5_yeast(display_long)|uniprotkb:MYO5(gene name)|psi-mi:MYO5(display_short)|uniprotkb:YMR109W(locus name)|uniprotkb:YM9718.08(orf name)|uniprotkb:Class I unconventional myosin MYO5(gene name synonym)|uniprotkb:Type I myosin MYO5(gene name synonym)|uniprotkb:Actin-dependent myosin-I MYO5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344148|imex:IM-14275-2747 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004362|refseq:NP_013474.3|dip:DIP-2218N|mint:Q05933|ensemblfungi:YLR370C(gene)|ensemblfungi:YLR370C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR007204(ARP2/3 complex, 21 kDa p21-Arc subunit)|interpro:IPR036753|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 ensemblfungi:YMR109W_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0009651"(response to salt stress)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051286"(cell tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071944"(cell periphery)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035535|ensemblfungi:YMR109W(gene)|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|rcsb pdb:1YP5|rcsb pdb:1ZUY|refseq:NP_013827.1|sgd:S000004715|mint:Q04439|dip:DIP-2222N psi-mi:"MI:0469"(intact) crc64:456EABC2B9CC4860 crc64:DFFB9EC16B61CD29 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Fj4cwULcw1TK5uS1lJczcNc5gns559292 rogid:n/Po/L9Xd7LP+fY39QaqP/s5US4559292 intact-crc:63166A9E6EE6E68D|rigid:FxIzvbbPZUPm843U5VfXVgvy6wI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05933 uniprotkb:Q05933 intact:EBI-2764|uniprotkb:D6VZ07|ensemblfungi:YLR370C intact:EBI-2764|uniprotkb:D6VZ07|ensemblfungi:YLR370C psi-mi:arpc3_yeast(display_long)|uniprotkb:ARC18(gene name)|psi-mi:ARC18(display_short)|uniprotkb:YLR370C(locus name)|uniprotkb:L8039.15(orf name)|uniprotkb:Arp2/3 complex 21 kDa subunit(gene name synonym) psi-mi:arpc3_yeast(display_long)|uniprotkb:ARC18(gene name)|psi-mi:ARC18(display_short)|uniprotkb:YLR370C(locus name)|uniprotkb:L8039.15(orf name)|uniprotkb:Arp2/3 complex 21 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344159|imex:IM-14275-2748 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004362|refseq:NP_013474.3|dip:DIP-2218N|mint:Q05933|ensemblfungi:YLR370C(gene)|ensemblfungi:YLR370C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR007204(ARP2/3 complex, 21 kDa p21-Arc subunit)|interpro:IPR036753|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 sgd:S000004362|refseq:NP_013474.3|dip:DIP-2218N|mint:Q05933|ensemblfungi:YLR370C(gene)|ensemblfungi:YLR370C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR007204(ARP2/3 complex, 21 kDa p21-Arc subunit)|interpro:IPR036753|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:456EABC2B9CC4860 crc64:456EABC2B9CC4860 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Fj4cwULcw1TK5uS1lJczcNc5gns559292 rogid:Fj4cwULcw1TK5uS1lJczcNc5gns559292 intact-crc:8700903BE1878779|rigid:9eZ7Q3NLd+SvAViN7X+Zgre0voE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12446 uniprotkb:Q05933 intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W intact:EBI-2764|uniprotkb:D6VZ07|ensemblfungi:YLR370C psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name) psi-mi:arpc3_yeast(display_long)|uniprotkb:ARC18(gene name)|psi-mi:ARC18(display_short)|uniprotkb:YLR370C(locus name)|uniprotkb:L8039.15(orf name)|uniprotkb:Arp2/3 complex 21 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344170|imex:IM-14275-2749 author score:87.56 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446 sgd:S000004362|refseq:NP_013474.3|dip:DIP-2218N|mint:Q05933|ensemblfungi:YLR370C(gene)|ensemblfungi:YLR370C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR007204(ARP2/3 complex, 21 kDa p21-Arc subunit)|interpro:IPR036753|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:4488355563AA2645 crc64:456EABC2B9CC4860 figure legend:tables S3 and S4|author-confidence:87.56|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292 rogid:Fj4cwULcw1TK5uS1lJczcNc5gns559292 intact-crc:778BEA9EA77DB9BD|rigid:4l3+nafPNSc2jqoqS9IWt8viVvg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05933 uniprotkb:Q6Q5K6 intact:EBI-2764|uniprotkb:D6VZ07|ensemblfungi:YLR370C intact:EBI-392766|ensemblfungi:YML058W-A|uniprotkb:D6VZB5 psi-mi:arpc3_yeast(display_long)|uniprotkb:ARC18(gene name)|psi-mi:ARC18(display_short)|uniprotkb:YLR370C(locus name)|uniprotkb:L8039.15(orf name)|uniprotkb:Arp2/3 complex 21 kDa subunit(gene name synonym) psi-mi:hug1_yeast(display_long)|uniprotkb:HUG1(gene name)|psi-mi:HUG1(display_short)|uniprotkb:YML058W-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344181|imex:IM-14275-2750 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004362|refseq:NP_013474.3|dip:DIP-2218N|mint:Q05933|ensemblfungi:YLR370C(gene)|ensemblfungi:YLR370C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR007204(ARP2/3 complex, 21 kDa p21-Arc subunit)|interpro:IPR036753|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 ensemblfungi:YML058W-A(gene)|ensemblfungi:YML058W-A_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:1905117"(regulation of ribonucleoside-diphosphate reductase activity)|go:"GO:1990846"(ribonucleoside-diphosphate reductase inhibitor activity)|sgd:S000007472|refseq:NP_219498.1|mint:Q6Q5K6 psi-mi:"MI:0469"(intact) crc64:456EABC2B9CC4860 - figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Fj4cwULcw1TK5uS1lJczcNc5gns559292 rogid:x+quBrnP+8yql7JGQ1NK4j5ubbw559292 intact-crc:DC34788C9355C3B1|rigid:g0vHgINnqd3brO5wktBFZRlSDE0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06078 uniprotkb:P25635 intact:EBI-359|uniprotkb:D6VZ43|ensemblfungi:YLR409C intact:EBI-14332|uniprotkb:P25633|uniprotkb:P25636|uniprotkb:D6VR63|ensemblfungi:YCR057C psi-mi:utp21_yeast(display_long)|uniprotkb:YLR409C(locus name)|uniprotkb:L8084.22(orf name)|uniprotkb:UTP21(gene name)|psi-mi:UTP21(display_short)|uniprotkb:U three protein 21(gene name synonym) psi-mi:pwp2_yeast(display_long)|uniprotkb:PWP2(gene name)|psi-mi:PWP2(display_short)|uniprotkb:UTP1(gene name synonym)|uniprotkb:YCR057C(locus name)|uniprotkb:YCR55C/YCR57C/YCR58C(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein 1(gene name synonym)|uniprotkb:U three protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344192|imex:IM-14275-2751 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004401|refseq:NP_013513.3|dip:DIP-6416N|mint:Q06078|ensemblfungi:YLR409C(gene)|ensemblfungi:YLR409C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR007319(Small-subunit processome, Utp21)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR036322|rcsb pdb:4HNX|rcsb pdb:4NSX|rcsb pdb:5JPQ|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR027145|interpro:IPR036322|rcsb pdb:5I2T|rcsb pdb:5WLC|rcsb pdb:5WYJ|ensemblfungi:YCR057C(gene)|ensemblfungi:YCR057C_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:5WYK|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_009984.1|sgd:S000000653|mint:P25635|dip:DIP-1868N psi-mi:"MI:0469"(intact) crc64:F1F856EF28369351 crc64:CBEE4720F81378B6 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p8cVdV7LI9hwgOSJSz2SUk+Z6Aw559292 rogid:3JKhaE50yPlCymnkEC14JB9atNY559292 intact-crc:3B15F4DE1D879AC9|rigid:HlUB+y8wWMO+QrspJe7uO7MMgWM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33892 uniprotkb:Q06098 intact:EBI-7442|uniprotkb:D6VTV8|ensemblfungi:YGL195W intact:EBI-38581|uniprotkb:D6W4A4|ensemblfungi:YPR106W psi-mi:gcn1_yeast(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:General control non-derepressible protein 1(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym)|uniprotkb:G1318(orf name)|uniprotkb:YGL195W(locus name) psi-mi:isr1_yeast(display_long)|uniprotkb:Inhibition of staurosporine resistance protein 1(gene name synonym)|uniprotkb:ISR1(gene name)|psi-mi:ISR1(display_short)|uniprotkb:YPR106W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344203|imex:IM-14275-2752 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003163|refseq:NP_011320.3|mint:P33892|dip:DIP-2344N|ensemblfungi:YGL195W(gene)|ensemblfungi:YGL195W_mRNA(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071264"(positive regulation of translational initiation in response to starvation)|go:"GO:0072755"(cellular response to benomyl)|go:"GO:0140469"(GCN2-mediated signaling)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1990451"(cellular stress response to acidic pH)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR022716|interpro:IPR033173|interpro:IPR034085 refseq:NP_015431.1|sgd:S000006310|mint:Q06098|dip:DIP-3818N|ensemblfungi:YPR106W(gene)|ensemblfungi:YPR106W_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0106279"(negative regulation of UDP-N-acetylglucosamine biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-381042 psi-mi:"MI:0469"(intact) crc64:980FDD03753E9D1C - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WPYtEB/xjy4g2cJFwhe+2teVYVk559292 rogid:vpRe+kNOvaubYTlrkPWxsjjsxCc559292 intact-crc:A640790B87B78890|rigid:OauHLisVxM3+OTos+ge0ti0foKI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06098 uniprotkb:Q03768 intact:EBI-38581|uniprotkb:D6W4A4|ensemblfungi:YPR106W intact:EBI-7618|uniprotkb:D6VSD4|ensemblfungi:YDR152W psi-mi:isr1_yeast(display_long)|uniprotkb:Inhibition of staurosporine resistance protein 1(gene name synonym)|uniprotkb:ISR1(gene name)|psi-mi:ISR1(display_short)|uniprotkb:YPR106W(locus name) psi-mi:gir2_yeast(display_long)|uniprotkb:GIR2(gene name)|psi-mi:GIR2(display_short)|uniprotkb:YDR152W(locus name)|uniprotkb:YD8358.08(orf name)|uniprotkb:DFRP2(gene name synonym)|uniprotkb:DRG family-regulatory protein 2(gene name synonym)|uniprotkb:Genetically interacts with ribosomal genes protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344214|imex:IM-14275-2753 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015431.1|sgd:S000006310|mint:Q06098|dip:DIP-3818N|ensemblfungi:YPR106W(gene)|ensemblfungi:YPR106W_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0106279"(negative regulation of UDP-N-acetylglucosamine biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-381042 sgd:S000002559|refseq:NP_010436.3|mint:Q03768|dip:DIP-1751N|ensemblfungi:YDR152W(gene)|ensemblfungi:YDR152W_mRNA(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR006575(RWD)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR040213 psi-mi:"MI:0469"(intact) - crc64:CE09A067388638ED figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vpRe+kNOvaubYTlrkPWxsjjsxCc559292 rogid:2gb8Bf2IGl8RoOmNcIvEMlmgeTE559292 intact-crc:B261E8E8600A03A2|rigid:3ejrEHwalETKHXaCKGCqMgSUPV0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06137 uniprotkb:P38426 intact:EBI-33827|uniprotkb:D6VYY4|ensemblfungi:YLR345W intact:EBI-19448|uniprotkb:D6W087|uniprotkb:Q6B1W2|ensemblfungi:YMR261C psi-mi:yl345_yeast(display_long)|uniprotkb:YLR345W(locus name) psi-mi:tps3_yeast(display_long)|uniprotkb:TPS3(gene name)|psi-mi:TPS3(display_short)|uniprotkb:YMR261C(locus name)|uniprotkb:YM8156.03C(orf name)|uniprotkb:Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 115 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344225|imex:IM-14275-2754 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013449.1|sgd:S000004337|mint:Q06137|dip:DIP-1500N|ensemblfungi:YLR345W(gene)|ensemblfungi:YLR345W_mRNA(transcript)|go:"GO:0003873"(6-phosphofructo-2-kinase activity)|go:"GO:0004331"(fructose-2,6-bisphosphate 2-phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006003"(fructose 2,6-bisphosphate metabolic process)|go:"GO:0006110"(regulation of glycolytic process)|interpro:IPR003094(Fructose-2,6-bisphosphatase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR013079(6-phosphofructo-2-kinase)|interpro:IPR027417|interpro:IPR029033|reactome:R-SCE-9634600 refseq:NP_013988.1|sgd:S000004874|ensemblfungi:YMR261C(gene)|ensemblfungi:YMR261C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005946"("alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)")|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR001830(Glycosyl transferase, family 20)|interpro:IPR003337(Trehalose-phosphatase)|interpro:IPR036412|dip:DIP-891N|mint:P38426 psi-mi:"MI:0469"(intact) crc64:29718CA8ECA8EB4E - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3s+qI70618y0XfFGywh7qUs4t6s559292 rogid:aY+Gu2+xxYxfe40pjJ1KTaYbDxM559292 intact-crc:A92D3287FA679F47|rigid:j45KKX0HEZIBcrUfuendpaXMx0I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06137 uniprotkb:P38634 intact:EBI-33827|uniprotkb:D6VYY4|ensemblfungi:YLR345W intact:EBI-17127|ensemblfungi:YLR079W|uniprotkb:D6VY79 psi-mi:yl345_yeast(display_long)|uniprotkb:YLR345W(locus name) psi-mi:sic1_yeast(display_long)|uniprotkb:SIC1(gene name)|psi-mi:SIC1(display_short)|uniprotkb:SDB25(gene name synonym)|uniprotkb:YLR079W(locus name)|uniprotkb:L9449.8(orf name)|uniprotkb:CDK inhibitor p40(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344236|imex:IM-14275-2755 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013449.1|sgd:S000004337|mint:Q06137|dip:DIP-1500N|ensemblfungi:YLR345W(gene)|ensemblfungi:YLR345W_mRNA(transcript)|go:"GO:0003873"(6-phosphofructo-2-kinase activity)|go:"GO:0004331"(fructose-2,6-bisphosphate 2-phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006003"(fructose 2,6-bisphosphate metabolic process)|go:"GO:0006110"(regulation of glycolytic process)|interpro:IPR003094(Fructose-2,6-bisphosphatase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR013079(6-phosphofructo-2-kinase)|interpro:IPR027417|interpro:IPR029033|reactome:R-SCE-9634600 ensemblfungi:YLR079W(gene)|ensemblfungi:YLR079W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016242"(negative regulation of macroautophagy)|rcsb pdb:3V7D|rcsb pdb:6G86|refseq:NP_013180.1|sgd:S000004069|dip:DIP-6817N|mint:P38634 psi-mi:"MI:0469"(intact) crc64:29718CA8ECA8EB4E crc64:7913636340678F78 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3s+qI70618y0XfFGywh7qUs4t6s559292 rogid:qU8ivBCZHvG4VmXDxv52yc08Hwc559292 intact-crc:E992F08E8420ACA8|rigid:vF67TxR3+uafzVUSdD19NUAmBRw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06137 uniprotkb:Q06146 intact:EBI-33827|uniprotkb:D6VYY4|ensemblfungi:YLR345W intact:EBI-36149|uniprotkb:D6VYQ4|ensemblfungi:YLR257W psi-mi:yl345_yeast(display_long)|uniprotkb:YLR345W(locus name) psi-mi:yl257_yeast(display_long)|uniprotkb:YLR257W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344247|imex:IM-14275-2756 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013449.1|sgd:S000004337|mint:Q06137|dip:DIP-1500N|ensemblfungi:YLR345W(gene)|ensemblfungi:YLR345W_mRNA(transcript)|go:"GO:0003873"(6-phosphofructo-2-kinase activity)|go:"GO:0004331"(fructose-2,6-bisphosphate 2-phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006003"(fructose 2,6-bisphosphate metabolic process)|go:"GO:0006110"(regulation of glycolytic process)|interpro:IPR003094(Fructose-2,6-bisphosphatase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR013079(6-phosphofructo-2-kinase)|interpro:IPR027417|interpro:IPR029033|reactome:R-SCE-9634600 sgd:S000004247|refseq:NP_013358.1|mint:Q06146|dip:DIP-4779N|ensemblfungi:YLR257W(gene)|ensemblfungi:YLR257W_mRNA(transcript)|go:"GO:0005737"(cytoplasm) psi-mi:"MI:0469"(intact) crc64:29718CA8ECA8EB4E - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3s+qI70618y0XfFGywh7qUs4t6s559292 rogid:SB7mpLFMvR1CbPIXfELPS7rdYiw559292 intact-crc:BFF3CB3DC704AF2A|rigid:R2TyWdZ6JxtEDTnxjud+MR0TClA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06144 uniprotkb:P10614 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344258|imex:IM-14275-2757 author score:92.65 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) crc64:2F474503CAB7C195 - figure legend:tables S3 and S4|author-confidence:92.65|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:318E31A3DCEF551C|rigid:J/PGi6hINYchf3vmFOirOIs3s/A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38264 uniprotkb:Q06144 intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344269|imex:IM-14275-2758 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:2F474503CAB7C195 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 intact-crc:269F46D50E9FE9D1|rigid:Vlhzqty0KlkEIUjV/2OLEpVoYuU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06144 uniprotkb:P38353 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W intact:EBI-18175|uniprotkb:D6VQS8|ensemblfungi:YBR283C psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:ssh1_yeast(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:Ssh1 complex subunit alpha(gene name synonym)|uniprotkb:Ssh1 complex subunit SSH1(gene name synonym)|uniprotkb:YBR2020(orf name)|uniprotkb:YBR283C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344280|imex:IM-14275-2759 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 refseq:NP_009842.1|sgd:S000000487|ensemblfungi:YBR283C(gene)|ensemblfungi:YBR283C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:2WW9|rcsb pdb:2WWA|dip:DIP-4962N|mint:P38353 psi-mi:"MI:0469"(intact) crc64:2F474503CAB7C195 crc64:48267EEA3E0191BD figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 rogid:76wvZIdv7W5BQn6wI+sHOGQAyuc559292 intact-crc:5ED327CA313017CE|rigid:jNsUj2U5U/yPqlW2oLa7HGePKc4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38694 uniprotkb:Q06144 intact:EBI-24511|uniprotkb:D3DKY6|ensemblfungi:YHR039C intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:msc7_yeast(display_long)|uniprotkb:MSC7(gene name)|psi-mi:MSC7(display_short)|uniprotkb:Meiotic sister-chromatid recombination protein 7(gene name synonym)|uniprotkb:YHR039C(locus name) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344291|imex:IM-14275-2760 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011904.1|sgd:S000001081|dip:DIP-1878N|mint:P38694|ensemblfungi:YHR039C(gene)|ensemblfungi:YHR039C_mRNA(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007131"(reciprocal meiotic recombination)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510 refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:2F474503CAB7C195 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p2xtb6/xYI/jfPNtO6JRZs+5t6I559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 intact-crc:DA0DC2D53454BC3C|rigid:tw/z5li5dV4XGxs9n/vJYLplW/8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39543 uniprotkb:Q06144 intact:EBI-26193|uniprotkb:D6VVZ9|ensemblfungi:YJL192C intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:sop4_yeast(display_long)|uniprotkb:Suppressor of PMA1-7 protein 4(gene name synonym)|uniprotkb:YJL192C(locus name)|uniprotkb:J0351(orf name)|uniprotkb:SOP4(gene name)|psi-mi:SOP4(display_short) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344302|imex:IM-14275-2761 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003728|refseq:NP_012343.1|mint:P39543|dip:DIP-5094N|ensemblfungi:YJL192C(gene)|ensemblfungi:YJL192C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR031395|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:2F474503CAB7C195 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:a+WulVpSm4gdxpcINNvDPLR2rZI559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 intact-crc:0A2F8EAB3596E5FE|rigid:ytib82RAQEZHqm8BUCk5BLX3Ey8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06144 uniprotkb:P40540 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W intact:EBI-24977|uniprotkb:D6VVQ3|ensemblfungi:YIL027C psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:emc5_yeast(display_long)|uniprotkb:EMC5(gene name)|psi-mi:EMC5(display_short)|uniprotkb:KRE27(gene name synonym)|uniprotkb:Killer toxin-resistance protein 27(gene name synonym)|uniprotkb:YIL027C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344313|imex:IM-14275-2762 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 refseq:NP_012237.1|sgd:S000001289|mint:P40540|dip:DIP-4937N|ensemblfungi:YIL027C(gene)|ensemblfungi:YIL027C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX psi-mi:"MI:0469"(intact) crc64:2F474503CAB7C195 crc64:6DBEEEE7722203B0 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 rogid:Ex5hBMZknjtCElxJOPBOPsjQZik559292 intact-crc:D517E243D51C6C71|rigid:qfPboMgL04ajXyEmHQOirlmrzqM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06144 uniprotkb:P54837 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344324|imex:IM-14275-2763 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:2F474503CAB7C195 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:345F4C37997178D4|rigid:acmKM3DLPIUB/Ye44UerHPDleT8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02774 uniprotkb:Q06144 intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344335|imex:IM-14275-2764 author score:89.41 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774 refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:2F474503CAB7C195 figure legend:tables S3 and S4|author-confidence:89.41|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 intact-crc:4E5E0E104654444A|rigid:+g8cx9flNJynkKWQOGi/YjFtIT0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06144 uniprotkb:Q04969 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W intact:EBI-27827|uniprotkb:D6VZB9|ensemblfungi:YML055W psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:spc2_yeast(display_long)|uniprotkb:YML055W(locus name)|uniprotkb:YM9958.07(orf name)|uniprotkb:SPC2(gene name)|psi-mi:SPC2(display_short)|uniprotkb:SPY1(gene name synonym)|uniprotkb:Microsomal signal peptidase subunit 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344346|imex:IM-14275-2765 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 refseq:NP_013657.1|sgd:S000004519|dip:DIP-4540N|mint:Q04969|ensemblfungi:YML055W(gene)|ensemblfungi:YML055W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit) psi-mi:"MI:0469"(intact) crc64:2F474503CAB7C195 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 rogid:ZXf9rPA3/ryPnDqI4JGp0VMNMe4559292 intact-crc:F12095A5E185C9DE|rigid:l80sforzkCZOz+1jP4wRvLBjrgk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05031 uniprotkb:Q06144 intact:EBI-27512|uniprotkb:D6W064|ensemblfungi:YMR238W intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:dfg5_yeast(display_long)|uniprotkb:DFG5(gene name)|psi-mi:DFG5(display_short)|uniprotkb:YMR238W(locus name)|uniprotkb:YM9959.20(orf name)|uniprotkb:Endo-alpha-1->6-D-mannanase DFG5(gene name synonym) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344357|imex:IM-14275-2766 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q05031|refseq:NP_013965.1|sgd:S000004851|dip:DIP-2739N|ensemblfungi:YMR238W(gene)|ensemblfungi:YMR238W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008496"(mannan endo-1,6-alpha-mannosidase activity)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0071555"(cell wall organization)|interpro:IPR005198(Glycoside hydrolase, family 76)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR014480(Mannan endo-1,6-alpha-mannosidase) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:2F474503CAB7C195 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nnHGptBCE3g8JbHRaiJvIbe4Nw8559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 intact-crc:AFAF13E11C20C63F|rigid:jK3I/FJNHUi7oVvTG6wzydbcAKs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:Q06144 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344368|imex:IM-14275-2767 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:2F474503CAB7C195 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 intact-crc:97D8B0C4EC6ED6F4|rigid:GpLgXXxTyiyQ+T4FCt6hreac7DM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06144 uniprotkb:Q06144 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344379|imex:IM-14275-2768 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) crc64:2F474503CAB7C195 crc64:2F474503CAB7C195 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 intact-crc:8FA5B96C55E4D78C|rigid:TrsCOBBW3CWFbdwa/CyW1usBCCU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06144 uniprotkb:Q12450 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W intact:EBI-6598|uniprotkb:D6W282|ensemblfungi:YOR016C psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:erp4_yeast(display_long)|uniprotkb:ERP4(gene name)|psi-mi:ERP4(display_short)|uniprotkb:YOR016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344390|imex:IM-14275-2769 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 refseq:NP_014659.1|sgd:S000005542|mint:Q12450|dip:DIP-7868N|ensemblfungi:YOR016C(gene)|ensemblfungi:YOR016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:2F474503CAB7C195 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 rogid:An7as6LjEDUYrLvEbua3xSL6bEk559292 intact-crc:FD18F78D783B7B15|rigid:lM5wrpgWllOgsrd+qjcCDBl48Bw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05790 uniprotkb:Q06147 intact:EBI-2055446|uniprotkb:D6VYL4|ensemblfungi:YLR213C intact:EBI-2069549|uniprotkb:D6VYQ7|ensemblfungi:YLR260W psi-mi:crr1_yeast(display_long)|uniprotkb:CRH-related protein 1(gene name synonym)|uniprotkb:YLR213C(locus name)|uniprotkb:CRR1(gene name)|psi-mi:CRR1(display_short) psi-mi:lcb5_yeast(display_long)|uniprotkb:LCB5(gene name)|psi-mi:LCB5(display_short)|uniprotkb:Sphinganine kinase 5(gene name synonym)|uniprotkb:YLR260W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344401|imex:IM-14275-2770 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013314.1|sgd:S000004203|dip:DIP-822N|mint:Q05790|ensemblfungi:YLR213C(gene)|ensemblfungi:YLR213C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0005619"(ascospore wall)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006037"(cell wall chitin metabolic process)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000757(Glycoside hydrolase, family 16)|interpro:IPR008264(Beta-glucanase)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup) interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|refseq:NP_013361.1|sgd:S000004250|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|mint:Q06147|ensemblfungi:YLR260W(gene)|ensemblfungi:YLR260W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001727"(lipid kinase activity)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0008481"(sphinganine kinase activity)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0017050"(D-erythro-sphingosine kinase activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046512"(sphingosine biosynthetic process)|reactome:R-SCE-1660661|reactome:R-SCE-390471|reactome:R-SCE-5218921|reactome:R-SCE-9009391 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:sxHumx7YQIRAuao76M7bC+L/NxM559292 rogid:y+IZsGat2aoq0AGR7AXfYM4dTHk559292 intact-crc:C324EEFFEBEBB11E|rigid:RzGmmypnJbXObSZscJ9kt6ni8p0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38009 uniprotkb:Q06151 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 intact:EBI-38973|uniprotkb:Q6Q5L1|uniprotkb:D6VYR7|ensemblfungi:YLR270W psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:dcps_yeast(display_long)|uniprotkb:DCS-1(gene name synonym)|uniprotkb:Hint-related 7meGMP-directed hydrolase 1(gene name synonym)|uniprotkb:DCS1(gene name)|psi-mi:DCS1(display_short)|uniprotkb:Scavenger mRNA-decapping enzyme DcpS(gene name synonym)|uniprotkb:YLR270W(locus name)|uniprotkb:Protein Dcs1p(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344412|imex:IM-14275-2771 author score:97.40 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N refseq:NP_013372.1|sgd:S000004260|mint:Q06151|dip:DIP-1480N|ensemblfungi:YLR270W(gene)|ensemblfungi:YLR270W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007584"(response to nutrient)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009408"(response to heat)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031086"(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044692"(exoribonuclease activator activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0090342"(regulation of cell aging)|go:"GO:1901919"(positive regulation of exoribonuclease activity)|interpro:IPR008594(Scavenger mRNA decapping enzyme)|interpro:IPR011145(Scavenger mRNA decapping enzyme, N-terminal)|interpro:IPR019808|interpro:IPR036265|rcsb pdb:5BV3|rcsb pdb:6TRQ|reactome:R-SCE-429958 psi-mi:"MI:0469"(intact) crc64:8ABA71761B512242 crc64:06A57C2344A3580A figure legend:tables S3 and S4|author-confidence:97.40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 rogid:63HqohkJUuNuZVKy4HcD1f0gGCg559292 intact-crc:95051C932A6A6E70|rigid:uC2HmNn+GSPw+zvVwRDVSKDUPm8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06162 uniprotkb:P50094 intact:EBI-34256|uniprotkb:D6VYV9|ensemblfungi:YLR315W intact:EBI-9195|ensemblfungi:YML056C|uniprotkb:Q2VQW8|uniprotkb:D6VZB8 psi-mi:nkp2_yeast(display_long)|uniprotkb:NKP2(gene name)|psi-mi:NKP2(display_short)|uniprotkb:Non-essential kinetochore protein 2(gene name synonym)|uniprotkb:YLR315W(locus name)|uniprotkb:Constitutive centromere-associated network protein NKP2(gene name synonym) psi-mi:imdh4_yeast(display_long)|uniprotkb:IMD4(gene name)|psi-mi:IMD4(display_short)|uniprotkb:YM9958.06C(orf name)|uniprotkb:YML056C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344423|imex:IM-14275-2772 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004307|refseq:NP_013419.1|mint:Q06162|dip:DIP-1939N|ensemblfungi:YLR315W(gene)|ensemblfungi:YLR315W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031511"(Mis6-Sim4 complex)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR018565|rcsb pdb:6NUW|rcsb pdb:6QLD|rcsb pdb:6QLE|rcsb pdb:6QLF ensemblfungi:YML056C(gene)|ensemblfungi:YML056C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|reactome:R-SCE-6798695|reactome:R-SCE-73817|refseq:NP_013656.1|sgd:S000004520|dip:DIP-6458N|mint:P50094 psi-mi:"MI:0469"(intact) - crc64:A73D1E4EFE8AEAD9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MT2+IEz8xQ2SVU5vvYYBI91cVKo559292 rogid:S70ravpil5p+waXS1zst4Ii27dY559292 intact-crc:013CB17CE23D3B9F|rigid:LkCyI+jC71ZiYp87ce5I7aZwLwU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06162 uniprotkb:P50095 intact:EBI-34256|uniprotkb:D6VYV9|ensemblfungi:YLR315W intact:EBI-9190|ensemblfungi:YLR432W|uniprotkb:D6VZ67 psi-mi:nkp2_yeast(display_long)|uniprotkb:NKP2(gene name)|psi-mi:NKP2(display_short)|uniprotkb:Non-essential kinetochore protein 2(gene name synonym)|uniprotkb:YLR315W(locus name)|uniprotkb:Constitutive centromere-associated network protein NKP2(gene name synonym) psi-mi:imdh3_yeast(display_long)|uniprotkb:IMD3(gene name)|psi-mi:IMD3(display_short)|uniprotkb:L9753.4(orf name)|uniprotkb:YLR432W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344434|imex:IM-14275-2773 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004307|refseq:NP_013419.1|mint:Q06162|dip:DIP-1939N|ensemblfungi:YLR315W(gene)|ensemblfungi:YLR315W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031511"(Mis6-Sim4 complex)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR018565|rcsb pdb:6NUW|rcsb pdb:6QLD|rcsb pdb:6QLE|rcsb pdb:6QLF ensemblfungi:YLR432W(gene)|ensemblfungi:YLR432W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|reactome:R-SCE-6798695|reactome:R-SCE-73817|refseq:NP_013536.3|sgd:S000004424|dip:DIP-1947N|mint:P50095 psi-mi:"MI:0469"(intact) - crc64:A0C84C22527AAEA6 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MT2+IEz8xQ2SVU5vvYYBI91cVKo559292 rogid:UUEyn+zhL8Z1aasK3r/inGhtO1c559292 intact-crc:003CB1785F44A3DD|rigid:Kfp34SaP26rThohpktx+nalNerE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06169 uniprotkb:Q06169 intact:EBI-31008|intact:EBI-937900|uniprotkb:Q66R43|uniprotkb:D6VYW6|ensemblfungi:YLR324W intact:EBI-31008|intact:EBI-937900|uniprotkb:Q66R43|uniprotkb:D6VYW6|ensemblfungi:YLR324W psi-mi:pex30_yeast(display_long)|uniprotkb:PEX30(gene name)|psi-mi:PEX30(display_short)|uniprotkb:Peroxin-30(gene name synonym)|uniprotkb:YLR324W(locus name) psi-mi:pex30_yeast(display_long)|uniprotkb:PEX30(gene name)|psi-mi:PEX30(display_short)|uniprotkb:Peroxin-30(gene name synonym)|uniprotkb:YLR324W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344445|imex:IM-14275-2774 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013428.1|sgd:S000004316|dip:DIP-1800N|mint:Q06169|ensemblfungi:YLR324W(gene)|ensemblfungi:YLR324W_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005933"(cellular bud)|go:"GO:0007031"(peroxisome organization)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071944"(cell periphery)|go:"GO:0097749"(membrane tubulation)|go:"GO:1900063"(regulation of peroxisome organization)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR010482(Integral peroxisomal membrane peroxin) refseq:NP_013428.1|sgd:S000004316|dip:DIP-1800N|mint:Q06169|ensemblfungi:YLR324W(gene)|ensemblfungi:YLR324W_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005933"(cellular bud)|go:"GO:0007031"(peroxisome organization)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071944"(cell periphery)|go:"GO:0097749"(membrane tubulation)|go:"GO:1900063"(regulation of peroxisome organization)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR010482(Integral peroxisomal membrane peroxin) psi-mi:"MI:0469"(intact) crc64:417DBE56B1C8B1D5 crc64:417DBE56B1C8B1D5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vkvJ4GqSW60wMG0m3ChlSzwcC3c559292 rogid:vkvJ4GqSW60wMG0m3ChlSzwcC3c559292 intact-crc:624DB5C62E0122FA|rigid:tYceXTS4/Br+Xaa+Ktmtn4Wt2+8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06178 uniprotkb:Q06178 intact:EBI-11803|ensemblfungi:YLR328W|uniprotkb:D6VYX0 intact:EBI-11803|ensemblfungi:YLR328W|uniprotkb:D6VYX0 psi-mi:nma1_yeast(display_long)|uniprotkb:NMA1(gene name)|psi-mi:NMA1(display_short)|uniprotkb:"NAD(+) pyrophosphorylase 1"(gene name synonym)|uniprotkb:"NAD(+) diphosphorylase 1"(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:L8543.16(orf name)|uniprotkb:YLR328W(locus name) psi-mi:nma1_yeast(display_long)|uniprotkb:NMA1(gene name)|psi-mi:NMA1(display_short)|uniprotkb:"NAD(+) pyrophosphorylase 1"(gene name synonym)|uniprotkb:"NAD(+) diphosphorylase 1"(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:L8543.16(orf name)|uniprotkb:YLR328W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344456|imex:IM-14275-2775 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR328W(gene)|ensemblfungi:YLR328W_mRNA(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|reactome:R-SCE-196807|refseq:NP_013432.1|sgd:S000004320|dip:DIP-1228N|mint:Q06178 ensemblfungi:YLR328W(gene)|ensemblfungi:YLR328W_mRNA(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|reactome:R-SCE-196807|refseq:NP_013432.1|sgd:S000004320|dip:DIP-1228N|mint:Q06178 psi-mi:"MI:0469"(intact) crc64:A176964E56A30DD8 crc64:A176964E56A30DD8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VzrKsykGbQsR8Eh7CHCwn/bCID8559292 rogid:VzrKsykGbQsR8Eh7CHCwn/bCID8559292 intact-crc:E2CA07EF9414692A|rigid:RdDYFZS2eAVeBL386r2JiFyAHAg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15496 uniprotkb:Q06213 intact:EBI-8902|ensemblfungi:YPL117C|uniprotkb:D6W3Q1 intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9 psi-mi:idi1_yeast(display_long)|uniprotkb:Isopentenyl pyrophosphate isomerase(gene name synonym)|uniprotkb:IDI1(gene name)|psi-mi:IDI1(display_short)|uniprotkb:BOT2(gene name synonym)|uniprotkb:YPL117C(locus name)|uniprotkb:LPH10C(orf name) psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344467|imex:IM-14275-2776 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL117C(gene)|ensemblfungi:YPL117C_mRNA(transcript)|go:"GO:0004452"(isopentenyl-diphosphate delta-isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009240"(isopentenyl diphosphate biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0045337"(farnesyl diphosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050992"(dimethylallyl diphosphate biosynthetic process)|reactome:R-SCE-191273|refseq:NP_015208.1|sgd:S000006038|interpro:IPR011876(Isopentenyl-diphosphate delta-isomerase, type 1)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|mint:P15496 ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N psi-mi:"MI:0469"(intact) - crc64:0E77A43A5222E862 figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:KQ9qSb2grQ4DQip7atYPeCwp5QM559292 rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292 intact-crc:F4A024C1DE9B1574|rigid:NRrgzk8tHiBq1tMHDvf7zRoMIA8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CX10 uniprotkb:Q06216 intact:EBI-6315262|ensemblfungi:YOR393W|ensemblfungi:YPL281C|uniprotkb:D6W385|uniprotkb:Q12007|uniprotkb:Q7LGJ4 intact:EBI-13413|uniprotkb:E9P964|uniprotkb:D6VYS0|ensemblfungi:YLR273C psi-mi:err1_yeast(display_long)|uniprotkb:ERR1(gene name)|psi-mi:ERR1(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:2-phosphoglycerate dehydratase(gene name synonym)|uniprotkb:YOR393W(locus name) psi-mi:pig1_yeast(display_long)|uniprotkb:PIG1(gene name)|psi-mi:PIG1(display_short)|uniprotkb:L9328.2(orf name)|uniprotkb:YLR273C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344478|imex:IM-14275-2777 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR393W(gene)|ensemblfungi:YOR393W_mRNA(transcript)|ensemblfungi:YPL281C(gene)|ensemblfungi:YPL281C_mRNA(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0006096"(glycolytic process)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|reactome:R-SCE-70171|reactome:R-SCE-70263|mint:P0CX10|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|refseq:NP_015038.1|refseq:NP_015042.1|sgd:S000005920|interpro:IPR029017|interpro:IPR036849 refseq:NP_013375.1|sgd:S000004263|mint:Q06216|dip:DIP-2918N|ensemblfungi:YLR273C(gene)|ensemblfungi:YLR273C_mRNA(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:2001069"(glycogen binding)|interpro:IPR005036(Putative phosphatase regulatory subunit)|interpro:IPR038175|reactome:R-SCE-3322077 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Vusa5LQZe98ke/mcTRdEnXReZDc559292 rogid:aKGiNt3sohd9EFbg5jgaD00HWbs559292 intact-crc:5C05727DAE799073|rigid:JVE/LE7xswJ577ktl3TKiNJjKjI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06217 uniprotkb:P38783 intact:EBI-235|uniprotkb:D6VYS2|ensemblfungi:YLR275W intact:EBI-24555|uniprotkb:D3DL08|ensemblfungi:YHR059W psi-mi:smd2_yeast(display_long)|uniprotkb:SMD2(gene name)|psi-mi:SMD2(display_short)|uniprotkb:YLR275W(locus name)|uniprotkb:L9328.5(orf name)|uniprotkb:snRNP core protein D2(gene name synonym) psi-mi:fyv4_yeast(display_long)|uniprotkb:FYV4(gene name)|psi-mi:FYV4(display_short)|uniprotkb:Function required for yeast viability protein 4(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS41(gene name synonym)|uniprotkb:YHR059W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344489|imex:IM-14275-2778 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004265|refseq:NP_013377.1|mint:Q06217|dip:DIP-1421N|ensemblfungi:YLR275W(gene)|ensemblfungi:YLR275W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027248|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V refseq:NP_011926.1|sgd:S000001101|dip:DIP-4906N|mint:P38783|ensemblfungi:YHR059W(gene)|ensemblfungi:YHR059W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR019083|interpro:IPR039603|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF psi-mi:"MI:0469"(intact) crc64:7287070B10E090C0 crc64:1662DB8385D067B9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rglZ3AQuJfa1rFYIeZLqiYj+L4U559292 rogid:bpqChwMYewyjUEHycGB2DzIGzBw559292 intact-crc:E99A034CCF4518D5|rigid:SvaLV48L6+PiPUEv0tEKLazzjVk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06679 uniprotkb:Q06344 intact:EBI-35712|uniprotkb:D6VSV7|ensemblfungi:YDR324C intact:EBI-34121|uniprotkb:D6VSZ4|ensemblfungi:YDR365C psi-mi:utp4_yeast(display_long)|uniprotkb:UTP4(gene name)|psi-mi:UTP4(display_short)|uniprotkb:t-UTP4(gene name synonym)|uniprotkb:U three protein 4(gene name synonym)|uniprotkb:U3 protein 4 required for transcription(gene name synonym)|uniprotkb:YDR324C(locus name) psi-mi:esf1_yeast(display_long)|uniprotkb:ESF1(gene name)|psi-mi:ESF1(display_short)|uniprotkb:18S rRNA factor 1(gene name synonym)|uniprotkb:YDR365C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344500|imex:IM-14275-2779 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010611.3|sgd:S000002732|mint:Q06679|dip:DIP-6436N|ensemblfungi:YDR324C(gene)|ensemblfungi:YDR324C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 refseq:NP_010653.1|sgd:S000002773|mint:Q06344|dip:DIP-5248N|ensemblfungi:YDR365C(gene)|ensemblfungi:YDR365C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|interpro:IPR012580(NUC153)|interpro:IPR039754 psi-mi:"MI:0469"(intact) crc64:5D1C77899CABB40B crc64:A16FB043D0ED86B7 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kAD4RO628jpcbjUoQXQbjcGVY88559292 rogid:b+EgEqRIl3bjezRrCv42j78ryTA559292 intact-crc:21B8520193F69DF0|rigid:8NDY9hZUrRlSxCm+hidWBuCPYg0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06407 uniprotkb:Q06407 intact:EBI-15060|uniprotkb:D6VT11|ensemblfungi:YDR379W intact:EBI-15060|uniprotkb:D6VT11|ensemblfungi:YDR379W psi-mi:rga2_yeast(display_long)|uniprotkb:RGA2(gene name)|psi-mi:RGA2(display_short)|uniprotkb:D9481.4(orf name)|uniprotkb:YDR379W(locus name) psi-mi:rga2_yeast(display_long)|uniprotkb:RGA2(gene name)|psi-mi:RGA2(display_short)|uniprotkb:D9481.4(orf name)|uniprotkb:YDR379W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344511|imex:IM-14275-2780 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010667.1|sgd:S000002787|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|ensemblfungi:YDR379W(gene)|ensemblfungi:YDR379W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|dip:DIP-2995N|mint:Q06407 refseq:NP_010667.1|sgd:S000002787|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|ensemblfungi:YDR379W(gene)|ensemblfungi:YDR379W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|dip:DIP-2995N|mint:Q06407 psi-mi:"MI:0469"(intact) crc64:FA13BA1DF8B35D98 crc64:FA13BA1DF8B35D98 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0nehE13u+4HaDfljPdHjDjR9znc559292 rogid:0nehE13u+4HaDfljPdHjDjR9znc559292 intact-crc:43D2847A51B85015|rigid:OsQ01g31a4Yd2qRWKYCWk9UcGJI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06490 uniprotkb:P43562 intact:EBI-33928|uniprotkb:D6W4C0|ensemblfungi:YPR121W intact:EBI-22828|uniprotkb:D6VTJ0|ensemblfungi:YFL040W psi-mi:thi22_yeast(display_long)|uniprotkb:THI22(gene name)|psi-mi:THI22(display_short)|uniprotkb:YPR121W(locus name) psi-mi:yfe0_yeast(display_long)|uniprotkb:YFL040W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344522|imex:IM-14275-2781 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015446.2|sgd:S000006325|mint:Q06490|dip:DIP-6441N|ensemblfungi:YPR121W(gene)|ensemblfungi:YPR121W_mRNA(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0008902"(hydroxymethylpyrimidine kinase activity)|go:"GO:0008972"(phosphomethylpyrimidine kinase activity)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0050334"(thiaminase activity)|interpro:IPR004305(TENA/THI-4 protein/Coenzyme PQQ biosynthesis protein C)|interpro:IPR004399(Phosphomethylpyrimidine kinase type-2)|interpro:IPR013749(Phosphomethylpyrimidine kinase type-1)|interpro:IPR016084(Haem oxygenase-like, multi-helical)|interpro:IPR027574|interpro:IPR029056 refseq:NP_116613.1|sgd:S000001854|dip:DIP-4427N|mint:P43562|ensemblfungi:YFL040W(gene)|ensemblfungi:YFL040W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005628"(prospore membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:7822B23A9546823C - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XPr1npPE/i5BwDB5pQcrNyMp6UU559292 rogid:JzbyxaDC75fewfwaoVCrVtHvmgU559292 intact-crc:ADFA4EF29147EEA1|rigid:IoxEYP/htSglIS/9KF42RA4b+4w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12462 uniprotkb:Q06497 intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C intact:EBI-36879|uniprotkb:D6W4C5|ensemblfungi:YPR128C psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:ant1_yeast(display_long)|uniprotkb:ANT1(gene name)|psi-mi:ANT1(display_short)|uniprotkb:YPR128C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344533|imex:IM-14275-2782 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) refseq:NP_015453.1|sgd:S000006332|mint:Q06497|dip:DIP-8825N|ensemblfungi:YPR128C(gene)|ensemblfungi:YPR128C_mRNA(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0005347"(ATP transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007031"(peroxisome organization)|go:"GO:0015217"(ADP transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|go:"GO:0015867"(ATP transport)|interpro:IPR018108|interpro:IPR023395 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 rogid:DH4ti6Peo5vXKjBQdHUMnb87XCs559292 intact-crc:0E35CFD1AD82683C|rigid:8jS84Yz4PogCJjxDMOeoAranDCM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08518 uniprotkb:Q06505 intact:EBI-15767|uniprotkb:Q12738|uniprotkb:Q7Z9Y0|uniprotkb:D6W2K8|ensemblfungi:YOR151C intact:EBI-32596|uniprotkb:D6W4C9|ensemblfungi:YPR133C psi-mi:rpb2_yeast(display_long)|uniprotkb:YOR151C(locus name)|uniprotkb:RPB2(gene name)|psi-mi:RPB2(display_short)|uniprotkb:RPB150(gene name synonym)|uniprotkb:RPO22(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym)|uniprotkb:B150(gene name synonym) psi-mi:iws1_yeast(display_long)|uniprotkb:SPN1(gene name)|psi-mi:SPN1(display_short)|uniprotkb:Interacts with SPT6 protein 1(gene name synonym)|uniprotkb:Suppresses postrecruitment functions protein 1(gene name synonym)|uniprotkb:IWS1(gene name synonym)|uniprotkb:YPR133C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344544|imex:IM-14275-2783 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005677|refseq:NP_014794.3|dip:DIP-14N|mint:P08518|ensemblfungi:YOR151C(gene)|ensemblfungi:YOR151C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519 refseq:NP_015458.1|sgd:S000006337|dip:DIP-3823N|mint:Q06505|ensemblfungi:YPR133C(gene)|ensemblfungi:YPR133C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070827"(obsolete chromatin maintenance)|interpro:IPR017923|interpro:IPR035441|rcsb pdb:3NFQ|rcsb pdb:3O8Z|rcsb pdb:3OAK|reactome:R-SCE-674695|reactome:R-SCE-75955 psi-mi:"MI:0469"(intact) crc64:BABD03212C0A583E crc64:7BC925FC8BA80E65 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:OtaUDREazRORKDcfBajDLPlXovY559292 rogid:ZGGEVh+io3MVCEa9lu5qnfaJURA559292 intact-crc:3970F33D3D630C9D|rigid:Jc++3Z182Oxnm/SDJWlqf5JBlOE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20434 uniprotkb:Q06505 intact:EBI-15781|uniprotkb:Q02121|ensemblfungi:YBR154C|uniprotkb:D6VQE9 intact:EBI-32596|uniprotkb:D6W4C9|ensemblfungi:YPR133C psi-mi:rpab1_yeast(display_long)|uniprotkb:RPB5(gene name)|psi-mi:RPB5(display_short)|uniprotkb:YBR154C(locus name)|uniprotkb:YBR1204(orf name)|uniprotkb:RPA7(gene name synonym)|uniprotkb:RPC9(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide(gene name synonym)|uniprotkb:ABC27(gene name synonym) psi-mi:iws1_yeast(display_long)|uniprotkb:SPN1(gene name)|psi-mi:SPN1(display_short)|uniprotkb:Interacts with SPT6 protein 1(gene name synonym)|uniprotkb:Suppresses postrecruitment functions protein 1(gene name synonym)|uniprotkb:IWS1(gene name synonym)|uniprotkb:YPR133C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344555|imex:IM-14275-2784 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|rcsb pdb:1WCM|rcsb pdb:1Y1V|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|rcsb pdb:2B63|rcsb pdb:2B8K|interpro:IPR020608|interpro:IPR020609|rcsb pdb:2E2H|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:1DZF|rcsb pdb:1I3Q|rcsb pdb:2E2I|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:5M5Y|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6H67|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:2E2J|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|ensemblfungi:YBR154C(gene)|ensemblfungi:YBR154C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4V1M|rcsb pdb:2JA5|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2JA6|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:2JA7|rcsb pdb:3GTG|rcsb pdb:2JA8|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:2NVQ|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4YM7|rcsb pdb:5C3E|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5G5L|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6H68|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|rcsb pdb:6UQ2|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-77075|reactome:R-SCE-9018519|refseq:NP_009712.1|sgd:S000000358|dip:DIP-71N|mint:P20434 refseq:NP_015458.1|sgd:S000006337|dip:DIP-3823N|mint:Q06505|ensemblfungi:YPR133C(gene)|ensemblfungi:YPR133C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070827"(obsolete chromatin maintenance)|interpro:IPR017923|interpro:IPR035441|rcsb pdb:3NFQ|rcsb pdb:3O8Z|rcsb pdb:3OAK|reactome:R-SCE-674695|reactome:R-SCE-75955 psi-mi:"MI:0469"(intact) crc64:2A15F7114D69D829 crc64:7BC925FC8BA80E65 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:j/jAJ2fXWf4ebK1aWTWrKERGUpM559292 rogid:ZGGEVh+io3MVCEa9lu5qnfaJURA559292 intact-crc:D5D114DCE837C42E|rigid:gCI3ZyCLqkNJ90qlz004Lx0/jH0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53874 uniprotkb:Q06506 intact:EBI-19873|uniprotkb:D6W101|ensemblfungi:YNL186W intact:EBI-35124|uniprotkb:D6W4D3|ensemblfungi:YPR137W psi-mi:ubp10_yeast(display_long)|uniprotkb:UBP10(gene name)|psi-mi:UBP10(display_short)|uniprotkb:YNL186W(locus name)|uniprotkb:N1619(orf name)|uniprotkb:Ubiquitin-specific-processing protease 10(gene name synonym)|uniprotkb:Deubiquitinating enzyme 10(gene name synonym)|uniprotkb:Disrupter of telomere silencing protein 4(gene name synonym)|uniprotkb:Ubiquitin thioesterase 10(gene name synonym)|uniprotkb:DOT4(gene name synonym) psi-mi:rrp9_yeast(display_long)|uniprotkb:RRP9(gene name)|psi-mi:RRP9(display_short)|uniprotkb:YPR137W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344566|imex:IM-14275-2785 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014213.2|sgd:S000005130|ensemblfungi:YNL186W(gene)|ensemblfungi:YNL186W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0043596"(nuclear replication fork)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|rcsb pdb:6RR0|dip:DIP-6664N|mint:P53874 refseq:NP_015463.1|sgd:S000006341|mint:Q06506|dip:DIP-6537N|ensemblfungi:YPR137W(gene)|ensemblfungi:YPR137W_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR039241|rcsb pdb:4J0X|rcsb pdb:5JPQ|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) - crc64:96BEAB7DC338E70E figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Z1rRAI9RLgHeGd7QwLbrf51v5LY559292 rogid:jcGY4AY3fUm5mEoDKsFxA6nvpQg559292 intact-crc:DC6A4E49B3E9D340|rigid:hUeLX4kFmxgD2xEJRGcN7w/YYnM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06132 uniprotkb:Q06506 intact:EBI-34377|uniprotkb:D6VYX6|ensemblfungi:YLR336C intact:EBI-35124|uniprotkb:D6W4D3|ensemblfungi:YPR137W psi-mi:sgd1_yeast(display_long)|uniprotkb:SGD1(gene name)|psi-mi:SGD1(display_short)|uniprotkb:YLR336C(locus name) psi-mi:rrp9_yeast(display_long)|uniprotkb:RRP9(gene name)|psi-mi:RRP9(display_short)|uniprotkb:YPR137W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344577|imex:IM-14275-2786 author score:99.26 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013440.1|sgd:S000004328|mint:Q06132|dip:DIP-6333N|ensemblfungi:YLR336C(gene)|ensemblfungi:YLR336C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097078"(FAL1-SGD1 complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold) refseq:NP_015463.1|sgd:S000006341|mint:Q06506|dip:DIP-6537N|ensemblfungi:YPR137W(gene)|ensemblfungi:YPR137W_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR039241|rcsb pdb:4J0X|rcsb pdb:5JPQ|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:8EEFDB8258407FF3 crc64:96BEAB7DC338E70E figure legend:tables S3 and S4|author-confidence:99.26|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FxZCxGejbcvEs/J2h1HEaWeVZLQ559292 rogid:jcGY4AY3fUm5mEoDKsFxA6nvpQg559292 intact-crc:030F6CAB24492446|rigid:Gv/LBIEAMbcldTAthbCA2Cr6dgY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CX10 uniprotkb:Q06541 intact:EBI-6315262|ensemblfungi:YOR393W|ensemblfungi:YPL281C|uniprotkb:D6W385|uniprotkb:Q12007|uniprotkb:Q7LGJ4 intact:EBI-31952|uniprotkb:Q2VQX3|uniprotkb:D6VYP0|ensemblfungi:YLR242C psi-mi:err1_yeast(display_long)|uniprotkb:ERR1(gene name)|psi-mi:ERR1(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:2-phosphoglycerate dehydratase(gene name synonym)|uniprotkb:YOR393W(locus name) psi-mi:arv1_yeast(display_long)|uniprotkb:ARV1(gene name)|psi-mi:ARV1(display_short)|uniprotkb:YLR242C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344588|imex:IM-14275-2787 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR393W(gene)|ensemblfungi:YOR393W_mRNA(transcript)|ensemblfungi:YPL281C(gene)|ensemblfungi:YPL281C_mRNA(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0006096"(glycolytic process)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|reactome:R-SCE-70171|reactome:R-SCE-70263|mint:P0CX10|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|refseq:NP_015038.1|refseq:NP_015042.1|sgd:S000005920|interpro:IPR029017|interpro:IPR036849 refseq:NP_013343.1|sgd:S000004232|dip:DIP-5171N|mint:Q06541|ensemblfungi:YLR242C(gene)|ensemblfungi:YLR242C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0032366"(intracellular sterol transport)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0035376"(sterol import)|go:"GO:0035621"(ER to Golgi ceramide transport)|go:"GO:0097036"(regulation of plasma membrane sterol distribution)|interpro:IPR007290(Arv1-like protein)|reactome:R-SCE-191273 psi-mi:"MI:0469"(intact) - crc64:2898F797A5805433 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Vusa5LQZe98ke/mcTRdEnXReZDc559292 rogid:s8BPIU0sgEKGowCoq6jNxtRgwYM559292 intact-crc:2ABB4087D8F4D737|rigid:Usf20wjfj6+6DpSH3lQY5qKhwOc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06549 uniprotkb:Q06549 intact:EBI-4455|ensemblfungi:YLR245C|uniprotkb:D6VYP3 intact:EBI-4455|ensemblfungi:YLR245C|uniprotkb:D6VYP3 psi-mi:cdd_yeast(display_long)|uniprotkb:CDD1(gene name)|psi-mi:CDD1(display_short)|uniprotkb:YLR245C(locus name)|uniprotkb:L9672.13(orf name)|uniprotkb:Cytidine aminohydrolase(gene name synonym) psi-mi:cdd_yeast(display_long)|uniprotkb:CDD1(gene name)|psi-mi:CDD1(display_short)|uniprotkb:YLR245C(locus name)|uniprotkb:L9672.13(orf name)|uniprotkb:Cytidine aminohydrolase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344599|imex:IM-14275-2788 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013346.1|sgd:S000004235|go:"GO:0006217"(deoxycytidine catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008655"(pyrimidine-containing compound salvage)|go:"GO:0009972"(cytidine deamination)|go:"GO:0042802"(identical protein binding)|go:"GO:0047844"(deoxycytidine deaminase activity)|ensemblfungi:YLR245C(gene)|ensemblfungi:YLR245C_mRNA(transcript)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR006262(Cytidine deaminase, homotetrameric)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:1R5T|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006216"(cytidine catabolic process)|reactome:R-SCE-6798695|mint:Q06549|dip:DIP-1252N|reactome:R-SCE-73614 refseq:NP_013346.1|sgd:S000004235|go:"GO:0006217"(deoxycytidine catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008655"(pyrimidine-containing compound salvage)|go:"GO:0009972"(cytidine deamination)|go:"GO:0042802"(identical protein binding)|go:"GO:0047844"(deoxycytidine deaminase activity)|ensemblfungi:YLR245C(gene)|ensemblfungi:YLR245C_mRNA(transcript)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR006262(Cytidine deaminase, homotetrameric)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:1R5T|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006216"(cytidine catabolic process)|reactome:R-SCE-6798695|mint:Q06549|dip:DIP-1252N|reactome:R-SCE-73614 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+bBpd3F/Pcvnc+F5LzAX3ia3tIk559292 rogid:+bBpd3F/Pcvnc+F5LzAX3ia3tIk559292 intact-crc:48CF4E5447BA5B41|rigid:jYF11JsNF+6OnYYJx2KLTTVhK9Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06551 uniprotkb:P43593 intact:EBI-37230|uniprotkb:Q6B217|uniprotkb:D6VYP4|ensemblfungi:YLR246W intact:EBI-19852|uniprotkb:D6VTP0|ensemblfungi:YFR010W psi-mi:erfb_yeast(display_long)|uniprotkb:DHHC cysteine-rich domain-containing protein ERF2(gene name synonym)|uniprotkb:Ras protein acyltransferase(gene name synonym)|uniprotkb:ERF2(gene name)|psi-mi:ERF2(display_short)|uniprotkb:YLR246W(locus name) psi-mi:ubp6_yeast(display_long)|uniprotkb:UBP6(gene name)|psi-mi:UBP6(display_short)|uniprotkb:Ubiquitin-specific-processing protease 6(gene name synonym)|uniprotkb:Deubiquitinating enzyme 6(gene name synonym)|uniprotkb:Ubiquitin thioesterase 6(gene name synonym)|uniprotkb:YFR010W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344610|imex:IM-14275-2789 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013347.1|sgd:S000004236|mint:Q06551|dip:DIP-4783N|ensemblfungi:YLR246W(gene)|ensemblfungi:YLR246W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031211"(endoplasmic reticulum palmitoyltransferase complex)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|interpro:IPR001594(Zinc finger, DHHC-type) refseq:NP_116665.1|sgd:S000001906|ensemblfungi:YFR010W(gene)|ensemblfungi:YFR010W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR000626(Ubiquitin)|interpro:IPR028889|interpro:IPR029071|interpro:IPR038765|interpro:IPR044635|rcsb pdb:1VJV|rcsb pdb:5A5B|rcsb pdb:5MPC|reactome:R-SCE-5689880|dip:DIP-6731N|mint:P43593 psi-mi:"MI:0469"(intact) - crc64:DAE54D1F8AC9960C figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6LBri1qWafIHxliiafTXrbrZ0JQ559292 rogid:M4HqdW/7V42HuFuSm4y6z4Oz6tg559292 intact-crc:74B200DC99ADDEC3|rigid:IMVW0fruzkAMiBwqOnvgkCJyHXg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06623 uniprotkb:Q96VH3 intact:EBI-38663|uniprotkb:D6W4H9|ensemblfungi:YPR179C intact:EBI-2044941|uniprotkb:D6VQZ3|ensemblfungi:YCL021W-A psi-mi:hda3_yeast(display_long)|uniprotkb:Histone deacetylase complex 1 subunit 3(gene name synonym)|uniprotkb:HDA3(gene name)|psi-mi:HDA3(display_short)|uniprotkb:PLO1(gene name synonym)|uniprotkb:YPR179C(locus name) psi-mi:yc021_yeast(display_long)|uniprotkb:YCL021W-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344621|imex:IM-14275-2790 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015505.1|sgd:S000006383|mint:Q06623|dip:DIP-4636N|ensemblfungi:YPR179C(gene)|ensemblfungi:YPR179C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0070823"(HDA1 complex)|interpro:IPR021006|interpro:IPR026216|interpro:IPR038609|rcsb pdb:3HGQ|rcsb pdb:3HGT|rcsb pdb:6Z6F|rcsb pdb:6Z6H|rcsb pdb:6Z6O|rcsb pdb:6Z6P sgd:S000007549|refseq:NP_065437.1|mint:Q96VH3|ensemblfungi:YCL021W-A(gene)|ensemblfungi:YCL021W-A_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rL/Axy69+g/ApTTWi7uWnItY22w559292 rogid:KPtxCFX4m13AghkJuoOkuTMuIWA559292 intact-crc:86A210299CF555E7|rigid:yUgbF8zJQsDjkmfHaXyk9vSUs5c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06630 uniprotkb:P32445 intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym) psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344632|imex:IM-14275-2791 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 psi-mi:"MI:0469"(intact) crc64:F26903A4814091C4 crc64:9F913C2FC9EF6E82 figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 intact-crc:2FFAEA4DEE5D6C22|rigid:Ln7NUjK86aroiHFa0oB8NUoZf/U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06672 uniprotkb:P41940 intact:EBI-31165|uniprotkb:D6VZ69|ensemblfungi:YLR435W intact:EBI-11191|uniprotkb:D6VRU1|ensemblfungi:YDL055C psi-mi:tsr2_yeast(display_long)|uniprotkb:TSR2(gene name)|psi-mi:TSR2(display_short)|uniprotkb:20S rRNA accumulation protein 2(gene name synonym)|uniprotkb:YLR435W(locus name) psi-mi:mpg1_yeast(display_long)|uniprotkb:YDL055C(locus name)|uniprotkb:PSA1(gene name)|psi-mi:PSA1(display_short)|uniprotkb:MPG1(gene name synonym)|uniprotkb:SRB1(gene name synonym)|uniprotkb:VIG9(gene name synonym)|uniprotkb:ATP-mannose-1-phosphate guanylyltransferase(gene name synonym)|uniprotkb:GDP-mannose pyrophosphorylase(gene name synonym)|uniprotkb:NDP-hexose pyrophosphorylase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344643|imex:IM-14275-2792 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013539.4|sgd:S000004427|ensemblfungi:YLR435W(gene)|ensemblfungi:YLR435W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR019398|rcsb pdb:6G03|rcsb pdb:6G04|dip:DIP-1584N|mint:Q06672 ensemblfungi:YDL055C(gene)|ensemblfungi:YDL055C_mRNA(transcript)|go:"GO:0004475"(mannose-1-phosphate guanylyltransferase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006486"(protein glycosylation)|go:"GO:0007049"(cell cycle)|go:"GO:0009298"(GDP-mannose biosynthetic process)|go:"GO:0000032"(cell wall mannoprotein biosynthetic process)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR018357|interpro:IPR029044|refseq:NP_010228.1|sgd:S000002213|mint:P41940|dip:DIP-4322N psi-mi:"MI:0469"(intact) - crc64:DBF1C39BEAE0B776 figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UEUsiuAzPFhonAYi3s6Ifb7Zm1Y559292 rogid:GRG89tGL6YWXVeYaorJ+bzXzj4E559292 intact-crc:0AEBFDA4528E5633|rigid:7NQPYRoUBQWQ/ll1cLFgVgW2yL8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22137 uniprotkb:Q06677 intact:EBI-4766|uniprotkb:D6VTU9|ensemblfungi:YGL206C intact:EBI-30084|uniprotkb:D6VSV1|ensemblfungi:YDR320C psi-mi:clh_yeast(display_long)|uniprotkb:CHC1(gene name)|psi-mi:CHC1(display_short)|uniprotkb:YGL206C(locus name) psi-mi:swa2_yeast(display_long)|uniprotkb:BUD24(gene name synonym)|uniprotkb:DnaJ-related protein SWA2(gene name synonym)|uniprotkb:Synthetic lethal with ARF1 protein 2(gene name synonym)|uniprotkb:Bud site selection protein 24(gene name synonym)|uniprotkb:SWA2(gene name)|psi-mi:SWA2(display_short)|uniprotkb:YDR320C(locus name)|uniprotkb:AUX1(gene name synonym)|uniprotkb:D9798.10(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344654|imex:IM-14275-2793 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011309.1|sgd:S000003174|dip:DIP-2279N|mint:P22137|ensemblfungi:YGL206C(gene)|ensemblfungi:YGL206C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0071439"(clathrin complex)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-432720|reactome:R-SCE-437239|reactome:R-SCE-8856828|reactome:R-SCE-8866427|reactome:R-SCE-8964038 refseq:NP_010606.1|sgd:S000002728|dip:DIP-2847N|mint:Q06677|ensemblfungi:YDR320C(gene)|ensemblfungi:YDR320C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0030276"(clathrin binding)|go:"GO:0031982"(vesicle)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR009060(UBA-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015228(Ubiquitin-associated)|interpro:IPR019734|interpro:IPR036869|rcsb pdb:1PGY|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:622F3083DF2FE315 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SAN6H3nVFozXZyTiRLaljMcIKIA559292 rogid:tlQB8sTn38IYFWzt5kqY+XywLcs559292 intact-crc:3061F6A58BD03223|rigid:0b6a9DQeq3ZJZbIrExEM1iBCDzg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06706 uniprotkb:P38874 intact:EBI-9068|uniprotkb:O00036|ensemblfungi:YLR384C|uniprotkb:D6VZ19 intact:EBI-9061|ensemblfungi:YHR187W|uniprotkb:D3DLD5 psi-mi:elp1_yeast(display_long)|uniprotkb:IKI3(gene name)|psi-mi:IKI3(display_short)|uniprotkb:YLR384C(locus name)|uniprotkb:L3502.7(orf name)|uniprotkb:ELP1(gene name synonym)|uniprotkb:TOT1(gene name synonym)|uniprotkb:Protein IKI3(gene name synonym)|uniprotkb:Gamma-toxin target 1(gene name synonym) psi-mi:elp5_yeast(display_long)|uniprotkb:YHR187W(locus name)|uniprotkb:IKI1(gene name)|psi-mi:IKI1(display_short)|uniprotkb:ELP5(gene name synonym)|uniprotkb:HAP2(gene name synonym)|uniprotkb:TOT5(gene name synonym)|uniprotkb:Gamma-toxin target 5(gene name synonym)|uniprotkb:Protein IKI1(gene name synonym)|uniprotkb:HAT-associated protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344665|imex:IM-14275-2794 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR384C(gene)|ensemblfungi:YLR384C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002926"(tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015031"(protein transport)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR006849(IKI3)|rcsb pdb:5CQS|rcsb pdb:6QK7|refseq:NP_013488.3|sgd:S000004376|dip:DIP-2384N|mint:Q06706 sgd:S000001230|ensemblfungi:YHR187W(gene)|ensemblfungi:YHR187W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR019519|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS|refseq:NP_012057.3|dip:DIP-1967N|mint:P38874 psi-mi:"MI:0469"(intact) crc64:7AEB1C0BA99282F6 crc64:DFD93D7BA583E2F5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:EnFV08kc3WWB6YjyTKs7hSDvjPA559292 rogid:Xl/ausdL/d79OM78at6ZZldvBMg559292 intact-crc:9AB0BF23E3A5B09F|rigid:V5QTkYCUY03GNHno/5Bp+n1B2lg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06706 uniprotkb:Q02884 intact:EBI-9068|uniprotkb:O00036|ensemblfungi:YLR384C|uniprotkb:D6VZ19 intact:EBI-35277|uniprotkb:D6W3R5|ensemblfungi:YPL101W psi-mi:elp1_yeast(display_long)|uniprotkb:IKI3(gene name)|psi-mi:IKI3(display_short)|uniprotkb:YLR384C(locus name)|uniprotkb:L3502.7(orf name)|uniprotkb:ELP1(gene name synonym)|uniprotkb:TOT1(gene name synonym)|uniprotkb:Protein IKI3(gene name synonym)|uniprotkb:Gamma-toxin target 1(gene name synonym) psi-mi:elp4_yeast(display_long)|uniprotkb:ELP4(gene name)|psi-mi:ELP4(display_short)|uniprotkb:Gamma-toxin target 7(gene name synonym)|uniprotkb:HAT-associated protein 1(gene name synonym)|uniprotkb:YPL101W(locus name)|uniprotkb:HAP1(gene name synonym)|uniprotkb:TOT7(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344676|imex:IM-14275-2795 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR384C(gene)|ensemblfungi:YLR384C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002926"(tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015031"(protein transport)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR006849(IKI3)|rcsb pdb:5CQS|rcsb pdb:6QK7|refseq:NP_013488.3|sgd:S000004376|dip:DIP-2384N|mint:Q06706 refseq:NP_015224.1|sgd:S000006022|mint:Q02884|dip:DIP-6718N|ensemblfungi:YPL101W(gene)|ensemblfungi:YPL101W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR008728(PAXNEB)|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS psi-mi:"MI:0469"(intact) crc64:7AEB1C0BA99282F6 crc64:276F0D1538EAA8FA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:EnFV08kc3WWB6YjyTKs7hSDvjPA559292 rogid:LLHmiDxhPIIxIElMn9yVWoFnY4Q559292 intact-crc:AF6CA426951D3C08|rigid:QKgyDLNtSpViqhfpAZHN/D0INXU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06708 uniprotkb:P43601 intact:EBI-27189|uniprotkb:D6VZ21|ensemblfungi:YLR386W intact:EBI-22968|uniprotkb:D6VTQ1|ensemblfungi:YFR021W psi-mi:vac14_yeast(display_long)|uniprotkb:YLR386W(locus name)|uniprotkb:L3502.1(orf name)|uniprotkb:Swollen vacuole phenotype 2 protein(gene name synonym)|uniprotkb:VAC14(gene name)|psi-mi:VAC14(display_short)|uniprotkb:SVP2(gene name synonym) psi-mi:atg18_yeast(display_long)|uniprotkb:NMR1(gene name synonym)|uniprotkb:YFR021W(locus name)|uniprotkb:ATG18(gene name)|psi-mi:ATG18(display_short)|uniprotkb:AUT10(gene name synonym)|uniprotkb:CVT18(gene name synonym)|uniprotkb:SVP1(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 18(gene name synonym)|uniprotkb:Swollen vacuole phenotype protein 1(gene name synonym)|uniprotkb:Needed for premeiotic replication protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344687|imex:IM-14275-2796 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004378|refseq:NP_013490.3|mint:Q06708|dip:DIP-1176N|ensemblfungi:YLR386W(gene)|ensemblfungi:YLR386W_mRNA(transcript)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070772"(PAS complex)|go:"GO:0090218"(positive regulation of lipid kinase activity)|go:"GO:1903778"(protein localization to vacuolar membrane)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR021841|interpro:IPR026825 refseq:NP_444297.1|sgd:S000001917|dip:DIP-5185N|mint:P43601|ensemblfungi:YFR021W(gene)|ensemblfungi:YFR021W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006497"(protein lipidation)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061908"(phagophore)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070772"(PAS complex)|go:"GO:0071944"(cell periphery)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:6KYB|reactome:R-SCE-1632852 psi-mi:"MI:0469"(intact) crc64:E625AB6F032D2E1B crc64:06B2DFAF842AE933 figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p3NeBDpj0EtuArZZ9ZUaR5XAWq8559292 rogid:dUJPRtNzoRFY/sp9LSteu2xC13A559292 intact-crc:6913522760AD5EAB|rigid:KX0A6K3AEbNDQExsSndiCFBASm0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53599 uniprotkb:Q07084 intact:EBI-18191|uniprotkb:D6W1K5|ensemblfungi:YNR031C intact:EBI-18184|uniprotkb:Q07909|uniprotkb:D6VY08|ensemblfungi:YLR006C psi-mi:ssk2_yeast(display_long)|uniprotkb:SSK2(gene name)|psi-mi:SSK2(display_short)|uniprotkb:YNR031C(locus name)|uniprotkb:N3276(orf name)|uniprotkb:Suppressor of sensor kinase 2(gene name synonym) psi-mi:ssk1_yeast(display_long)|uniprotkb:YLR006C(locus name)|uniprotkb:SSK1(gene name)|psi-mi:SSK1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344698|imex:IM-14275-2797 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014428.1|sgd:S000005314|ensemblfungi:YNR031C(gene)|ensemblfungi:YNR031C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0003779"(actin binding)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007234"(osmosensory signaling via phosphorelay pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017240(MAP kinase kinase kinase, SSK22)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-389357|dip:DIP-2436N|mint:P53599 refseq:NP_013106.1|sgd:S000003996|ensemblfungi:YLR006C(gene)|ensemblfungi:YLR006C_mRNA(transcript)|go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007234"(osmosensory signaling via phosphorelay pathway)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:1990315"(Mcs4 RR-MAPKKK complex)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|rcsb pdb:5KBX|dip:DIP-2437N|mint:Q07084 psi-mi:"MI:0469"(intact) crc64:91A07A195CB3772E crc64:33B2DBB4FCF2528A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0Syq+NfHfzuqKTtNtN+kjya9ejc559292 rogid:xmyX+JrLkDhsvw7i7m+FHfBWmV0559292 intact-crc:F3290FBDCA9F1881|rigid:KWX2d1vAL7BD1mkkRd7N+bstHew false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07084 uniprotkb:Q07688 intact:EBI-18184|uniprotkb:Q07909|uniprotkb:D6VY08|ensemblfungi:YLR006C intact:EBI-34423|uniprotkb:D6VRC1|ensemblfungi:YDL235C psi-mi:ssk1_yeast(display_long)|uniprotkb:YLR006C(locus name)|uniprotkb:SSK1(gene name)|psi-mi:SSK1(display_short) psi-mi:ypd1_yeast(display_long)|uniprotkb:YPD1(gene name)|psi-mi:YPD1(display_short)|uniprotkb:Histidine-containing phosphotransfer protein YPD1(gene name synonym)|uniprotkb:Tyrosine phosphatase-dependent protein 1(gene name synonym)|uniprotkb:D0790(orf name)|uniprotkb:YDL235C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344709|imex:IM-14275-2798 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013106.1|sgd:S000003996|ensemblfungi:YLR006C(gene)|ensemblfungi:YLR006C_mRNA(transcript)|go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007234"(osmosensory signaling via phosphorelay pathway)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:1990315"(Mcs4 RR-MAPKKK complex)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|rcsb pdb:5KBX|dip:DIP-2437N|mint:Q07084 refseq:NP_010046.1|sgd:S000002394|mint:Q07688|dip:DIP-5899N|ensemblfungi:YDL235C(gene)|ensemblfungi:YDL235C_mRNA(transcript)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007234"(osmosensory signaling via phosphorelay pathway)|go:"GO:0009927"(histidine phosphotransfer kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016772"(transferase activity, transferring phosphorus-containing groups)|go:"GO:0043424"(protein histidine kinase binding)|interpro:IPR008207("Signal transduction histidine kinase, phosphotransfer (Hpt) region")|interpro:IPR036641|rcsb pdb:1C02|rcsb pdb:1C03|rcsb pdb:1OXB|rcsb pdb:1OXK|rcsb pdb:1QSP|rcsb pdb:2R25|rcsb pdb:5KBX|rcsb pdb:6M7W psi-mi:"MI:0469"(intact) crc64:33B2DBB4FCF2528A crc64:4B923E621C57783D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:xmyX+JrLkDhsvw7i7m+FHfBWmV0559292 rogid:YN/TB6a79rhT0M1R09pLAyj/Xac559292 intact-crc:959EA1A1FBCC637C|rigid:HazSyPP+a2TppSCg0sMWxDlzrwg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07457 uniprotkb:P21304 intact:EBI-31563|uniprotkb:D6VRS5|ensemblfungi:YDL074C intact:EBI-14328|uniprotkb:D6VYJ9|ensemblfungi:YLR196W psi-mi:bre1_yeast(display_long)|uniprotkb:BRE1(gene name)|psi-mi:BRE1(display_short)|uniprotkb:Brefeldin A-sensitivity protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1(gene name synonym)|uniprotkb:YDL074C(locus name) psi-mi:pwp1_yeast(display_long)|uniprotkb:L8167.10(orf name)|uniprotkb:YLR196W(locus name)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344720|imex:IM-14275-2799 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010209.1|sgd:S000002232|dip:DIP-2999N|mint:Q07457|ensemblfungi:YDL074C(gene)|ensemblfungi:YDL074C_mRNA(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006348"|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|rcsb pdb:4R7E refseq:NP_013297.1|sgd:S000004186|ensemblfungi:YLR196W(gene)|ensemblfungi:YLR196W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR044285|mint:P21304|dip:DIP-4203N psi-mi:"MI:0469"(intact) crc64:FC6B32825970D36F crc64:FC0189B289494AB5 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oDMRE2wudyOH91xTQ/+8jKN+0L0559292 rogid:Q1nPXtlkpIw8JosaiYX0PSVNaSw559292 intact-crc:FAB01A50A298E208|rigid:tlI6WWN6cAxGXDdxB410U4VnK2Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07457 uniprotkb:Q06411 intact:EBI-31563|uniprotkb:D6VRS5|ensemblfungi:YDL074C intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W psi-mi:bre1_yeast(display_long)|uniprotkb:BRE1(gene name)|psi-mi:BRE1(display_short)|uniprotkb:Brefeldin A-sensitivity protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1(gene name synonym)|uniprotkb:YDL074C(locus name) psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344731|imex:IM-14275-2800 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010209.1|sgd:S000002232|dip:DIP-2999N|mint:Q07457|ensemblfungi:YDL074C(gene)|ensemblfungi:YDL074C_mRNA(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006348"|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|rcsb pdb:4R7E refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88 psi-mi:"MI:0469"(intact) crc64:FC6B32825970D36F crc64:9986B547B9582338 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oDMRE2wudyOH91xTQ/+8jKN+0L0559292 rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292 intact-crc:30EC70F1C3C44F8D|rigid:UWdjCQw8LeyeQs6R4iSxrBSNSVk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07528 uniprotkb:P32319 intact:EBI-36894|uniprotkb:D6VRN7|ensemblfungi:YDL113C intact:EBI-13123|uniprotkb:D6VPY3|ensemblfungi:YBL017C psi-mi:atg20_yeast(display_long)|uniprotkb:ATG20(gene name)|psi-mi:ATG20(display_short)|uniprotkb:YDL113C(locus name)|uniprotkb:Cytoplasm to vacuole targeting protein 20(gene name synonym)|uniprotkb:Sorting nexin-42(gene name synonym)|uniprotkb:CVT20(gene name synonym)|uniprotkb:SNX42(gene name synonym) psi-mi:vps10_yeast(display_long)|uniprotkb:PEP1(gene name)|psi-mi:PEP1(display_short)|uniprotkb:Vacuolar carboxypeptidase sorting receptor VPS10(gene name synonym)|uniprotkb:Carboxypeptidase Y receptor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 1(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 1(gene name synonym)|uniprotkb:Sortilin VPS10(gene name synonym)|uniprotkb:VPS10(gene name synonym)|uniprotkb:VPT1(gene name synonym)|uniprotkb:YBL03.22(orf name)|uniprotkb:YBL0302(orf name)|uniprotkb:YBL017C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344742|imex:IM-14275-2801 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010170.1|sgd:S000002271|mint:Q07528|dip:DIP-1593N|ensemblfungi:YDL113C(gene)|ensemblfungi:YDL113C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034498"(early endosome to Golgi transport)|interpro:IPR001683(Phox-like)|interpro:IPR027267|interpro:IPR036871|interpro:IPR044106 refseq:NP_009536.1|sgd:S000000113|mint:P32319|dip:DIP-5900N|ensemblfungi:YBL017C(gene)|ensemblfungi:YBL017C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000423"(mitophagy)|go:"GO:0000425"(pexophagy)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048203"(vesicle targeting, trans-Golgi to endosome)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR036278 psi-mi:"MI:0469"(intact) crc64:160977A8BECB6D93 crc64:C778A0400612ECF4 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BWykOKWex5TB/nRzSUOXdZlM8yk559292 rogid:dYYsekAaDw4SzmEUSe5tYb5a43M559292 intact-crc:7B4A4E044BC62C6F|rigid:lE1YMSd0IJMUeP7ngbDOA6m+f0k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07528 uniprotkb:P47057 intact:EBI-36894|uniprotkb:D6VRN7|ensemblfungi:YDL113C intact:EBI-17610|ensemblfungi:YJL036W|uniprotkb:Q06794|uniprotkb:D6VWE7 psi-mi:atg20_yeast(display_long)|uniprotkb:ATG20(gene name)|psi-mi:ATG20(display_short)|uniprotkb:YDL113C(locus name)|uniprotkb:Cytoplasm to vacuole targeting protein 20(gene name synonym)|uniprotkb:Sorting nexin-42(gene name synonym)|uniprotkb:CVT20(gene name synonym)|uniprotkb:SNX42(gene name synonym) psi-mi:snx4_yeast(display_long)|uniprotkb:SNX4(gene name)|psi-mi:SNX4(display_short)|uniprotkb:YJL036W(locus name)|uniprotkb:J1244(orf name)|uniprotkb:ATG24(gene name synonym)|uniprotkb:CVT13(gene name synonym)|uniprotkb:Autophagy-related protein 24(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 13(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344753|imex:IM-14275-2802 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010170.1|sgd:S000002271|mint:Q07528|dip:DIP-1593N|ensemblfungi:YDL113C(gene)|ensemblfungi:YDL113C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034498"(early endosome to Golgi transport)|interpro:IPR001683(Phox-like)|interpro:IPR027267|interpro:IPR036871|interpro:IPR044106 ensemblfungi:YJL036W(gene)|ensemblfungi:YJL036W_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006914"(autophagy)|go:"GO:0010008"(endosome membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0036010"(protein localization to endosome)|interpro:IPR001683(Phox-like)|interpro:IPR027267|interpro:IPR036871|refseq:NP_012498.1|sgd:S000003573|dip:DIP-2707N|mint:P47057 psi-mi:"MI:0469"(intact) crc64:160977A8BECB6D93 crc64:10964322A1A22F16 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BWykOKWex5TB/nRzSUOXdZlM8yk559292 rogid:v2ovPWNoSLV6IT1ikMFW57ArKVE559292 intact-crc:7FC6C4331AE7884F|rigid:CSzEV5uAX3Nd3ZBHbTd9EN295bU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07528 uniprotkb:Q03860 intact:EBI-36894|uniprotkb:D6VRN7|ensemblfungi:YDL113C intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:atg20_yeast(display_long)|uniprotkb:ATG20(gene name)|psi-mi:ATG20(display_short)|uniprotkb:YDL113C(locus name)|uniprotkb:Cytoplasm to vacuole targeting protein 20(gene name synonym)|uniprotkb:Sorting nexin-42(gene name synonym)|uniprotkb:CVT20(gene name synonym)|uniprotkb:SNX42(gene name synonym) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344764|imex:IM-14275-2803 author score:92.26 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010170.1|sgd:S000002271|mint:Q07528|dip:DIP-1593N|ensemblfungi:YDL113C(gene)|ensemblfungi:YDL113C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034498"(early endosome to Golgi transport)|interpro:IPR001683(Phox-like)|interpro:IPR027267|interpro:IPR036871|interpro:IPR044106 sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) crc64:160977A8BECB6D93 crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:92.26|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BWykOKWex5TB/nRzSUOXdZlM8yk559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:612517EB41583202|rigid:2fpZIJNIoio7KmAMKQPgMZf1Dc8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32386 uniprotkb:Q07549 intact:EBI-21511|uniprotkb:Q07882|uniprotkb:D6VXW0|ensemblfungi:YLL048C intact:EBI-22078|uniprotkb:D6VRM7|ensemblfungi:YDL123W psi-mi:ybt1_yeast(display_long)|uniprotkb:YBT1(gene name)|psi-mi:YBT1(display_short)|uniprotkb:BAT1(gene name synonym)|uniprotkb:YLL048C(locus name) psi-mi:sna4_yeast(display_long)|uniprotkb:YDL123W(locus name)|uniprotkb:SNA4(gene name)|psi-mi:SNA4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344775|imex:IM-14275-2804 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013052.1|sgd:S000003971|mint:P32386|dip:DIP-6474N|ensemblfungi:YLL048C(gene)|ensemblfungi:YLL048C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006816"(calcium ion transport)|go:"GO:0015718"(monocarboxylic acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033285"(ATPase-coupled monocarboxylic acid transmembrane transporter activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 refseq:NP_010160.1|sgd:S000002281|dip:DIP-2816N|ensemblfungi:YDL123W(gene)|ensemblfungi:YDL123W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000612(Protein of unknown function UPF0057)|mint:Q07549 psi-mi:"MI:0469"(intact) crc64:E71D3D57A3013C38 crc64:3B9378FD5EDDFA5A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:b0Cz526nha/7DJPmG1uADmBnNPA559292 rogid:FYmk+8JkkE8m9CdHoTlaoPRxZtU559292 intact-crc:085BD3224218F57A|rigid:FukbhETGY2JL09I5ZqfgtFSwnrs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:Q07549 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-22078|uniprotkb:D6VRM7|ensemblfungi:YDL123W psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:sna4_yeast(display_long)|uniprotkb:YDL123W(locus name)|uniprotkb:SNA4(gene name)|psi-mi:SNA4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344786|imex:IM-14275-2805 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N refseq:NP_010160.1|sgd:S000002281|dip:DIP-2816N|ensemblfungi:YDL123W(gene)|ensemblfungi:YDL123W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000612(Protein of unknown function UPF0057)|mint:Q07549 psi-mi:"MI:0469"(intact) - crc64:3B9378FD5EDDFA5A figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:FYmk+8JkkE8m9CdHoTlaoPRxZtU559292 intact-crc:7B95C74FBBE9B643|rigid:qspjSngLhdjZcAMpJ2UtQKXlqGU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32610 uniprotkb:Q07549 intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W intact:EBI-22078|uniprotkb:D6VRM7|ensemblfungi:YDL123W psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym) psi-mi:sna4_yeast(display_long)|uniprotkb:YDL123W(locus name)|uniprotkb:SNA4(gene name)|psi-mi:SNA4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344797|imex:IM-14275-2806 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610 refseq:NP_010160.1|sgd:S000002281|dip:DIP-2816N|ensemblfungi:YDL123W(gene)|ensemblfungi:YDL123W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000612(Protein of unknown function UPF0057)|mint:Q07549 psi-mi:"MI:0469"(intact) crc64:FDE93E1FAF0AEC5B crc64:3B9378FD5EDDFA5A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292 rogid:FYmk+8JkkE8m9CdHoTlaoPRxZtU559292 intact-crc:EF603639EC4D5933|rigid:vc7/aQlHJKse+bA1RwhcRO/pIiw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07549 uniprotkb:P34110 intact:EBI-22078|uniprotkb:D6VRM7|ensemblfungi:YDL123W intact:EBI-20415|uniprotkb:D6VW33|ensemblfungi:YJL154C psi-mi:sna4_yeast(display_long)|uniprotkb:YDL123W(locus name)|uniprotkb:SNA4(gene name)|psi-mi:SNA4(display_short) psi-mi:vps35_yeast(display_long)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:Vacuolar protein-targeting protein 7(gene name synonym)|uniprotkb:VPT7(gene name synonym)|uniprotkb:J0580(orf name)|uniprotkb:YJL154C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344808|imex:IM-14275-2807 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010160.1|sgd:S000002281|dip:DIP-2816N|ensemblfungi:YDL123W(gene)|ensemblfungi:YDL123W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000612(Protein of unknown function UPF0057)|mint:Q07549 refseq:NP_012381.1|sgd:S000003690|ensemblfungi:YJL154C(gene)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1904377"(positive regulation of protein localization to cell periphery)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR042491|reactome:R-SCE-3238698|ensemblfungi:YJL154C_mRNA(transcript)|dip:DIP-1743N|mint:P34110 psi-mi:"MI:0469"(intact) crc64:3B9378FD5EDDFA5A crc64:DE1BC57B9DFB606E figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FYmk+8JkkE8m9CdHoTlaoPRxZtU559292 rogid:5KBi/lSF+BsMyg9ulP9eLCp2xCc559292 intact-crc:4BEBC0AFEC5270D0|rigid:mZ8Pb0miUIVPKwnSd/6YiOmNmKk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07549 uniprotkb:P35844 intact:EBI-22078|uniprotkb:D6VRM7|ensemblfungi:YDL123W intact:EBI-9648|ensemblfungi:YPL145C|uniprotkb:D6W3M4|uniprotkb:E9P8U8 psi-mi:sna4_yeast(display_long)|uniprotkb:YDL123W(locus name)|uniprotkb:SNA4(gene name)|psi-mi:SNA4(display_short) psi-mi:kes1_yeast(display_long)|uniprotkb:KES1(gene name)|psi-mi:KES1(display_short)|uniprotkb:OSH4(gene name synonym)|uniprotkb:Protein KES1(gene name synonym)|uniprotkb:LPI3C(orf name)|uniprotkb:P2614(orf name)|uniprotkb:YPL145C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344819|imex:IM-14275-2808 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010160.1|sgd:S000002281|dip:DIP-2816N|ensemblfungi:YDL123W(gene)|ensemblfungi:YDL123W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000612(Protein of unknown function UPF0057)|mint:Q07549 ensemblfungi:YPL145C(gene)|ensemblfungi:YPL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035621"(ER to Golgi ceramide transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|rcsb pdb:1ZHT|rcsb pdb:1ZHW|rcsb pdb:1ZHX|rcsb pdb:1ZHY|rcsb pdb:1ZHZ|rcsb pdb:1ZI7|rcsb pdb:3SPW|rcsb pdb:4F4B|rcsb pdb:4FES|rcsb pdb:4JCH|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_015180.1|sgd:S000006066|dip:DIP-2867N|mint:P35844 psi-mi:"MI:0469"(intact) crc64:3B9378FD5EDDFA5A - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FYmk+8JkkE8m9CdHoTlaoPRxZtU559292 rogid:6vsHrA4RScGr2+xmii0wiuvK1OM559292 intact-crc:1965F40C0FDDDC29|rigid:QaaeWoim1n92bW+8ukDYc4cRYRg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38310 uniprotkb:Q07549 intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W intact:EBI-22078|uniprotkb:D6VRM7|ensemblfungi:YDL123W psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:sna4_yeast(display_long)|uniprotkb:YDL123W(locus name)|uniprotkb:SNA4(gene name)|psi-mi:SNA4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344830|imex:IM-14275-2809 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1) refseq:NP_010160.1|sgd:S000002281|dip:DIP-2816N|ensemblfungi:YDL123W(gene)|ensemblfungi:YDL123W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000612(Protein of unknown function UPF0057)|mint:Q07549 psi-mi:"MI:0469"(intact) crc64:7B4E620ABC39A053 crc64:3B9378FD5EDDFA5A figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 rogid:FYmk+8JkkE8m9CdHoTlaoPRxZtU559292 intact-crc:5E3F0593EC5B3D3D|rigid:NBdEexB/uMgwyWIK7ZRVWZ3lwsM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07549 uniprotkb:P38929 intact:EBI-22078|uniprotkb:D6VRM7|ensemblfungi:YDL123W intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W psi-mi:sna4_yeast(display_long)|uniprotkb:YDL123W(locus name)|uniprotkb:SNA4(gene name)|psi-mi:SNA4(display_short) psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344841|imex:IM-14275-2810 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010160.1|sgd:S000002281|dip:DIP-2816N|ensemblfungi:YDL123W(gene)|ensemblfungi:YDL123W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000612(Protein of unknown function UPF0057)|mint:Q07549 refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 psi-mi:"MI:0469"(intact) crc64:3B9378FD5EDDFA5A crc64:5BD9ECFF8508F396 figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FYmk+8JkkE8m9CdHoTlaoPRxZtU559292 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 intact-crc:7C39CFB2B7057CF8|rigid:HGRCT0hNYtRVflWsyyKLGC3/Svg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07549 uniprotkb:P39111 intact:EBI-22078|uniprotkb:D6VRM7|ensemblfungi:YDL123W intact:EBI-20272|uniprotkb:D6VUF5|ensemblfungi:YGR020C psi-mi:sna4_yeast(display_long)|uniprotkb:YDL123W(locus name)|uniprotkb:SNA4(gene name)|psi-mi:SNA4(display_short) psi-mi:vatf_yeast(display_long)|uniprotkb:VMA7(gene name)|psi-mi:VMA7(display_short)|uniprotkb:YGR020C(locus name)|uniprotkb:Vacuolar proton pump subunit F(gene name synonym)|uniprotkb:V-ATPase 14 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344852|imex:IM-14275-2811 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010160.1|sgd:S000002281|dip:DIP-2816N|ensemblfungi:YDL123W(gene)|ensemblfungi:YDL123W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000612(Protein of unknown function UPF0057)|mint:Q07549 refseq:NP_011534.1|sgd:S000003252|ensemblfungi:YGR020C(gene)|ensemblfungi:YGR020C_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016020"(membrane)|go:"GO:0042625"(ATPase-coupled ion transmembrane transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005772(ATPase, V1 complex, subunit F, eukaryotic)|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|interpro:IPR036906|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4IX9|rcsb pdb:4RND|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2077N|mint:P39111 psi-mi:"MI:0469"(intact) crc64:3B9378FD5EDDFA5A crc64:D21EC0980EB99DFF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FYmk+8JkkE8m9CdHoTlaoPRxZtU559292 rogid:VtthQl2jj9fpjv3psX0YUNbIAKU559292 intact-crc:3F185B96512BDB31|rigid:jVkJL1QtnKkcf14EvPPPf5N+80Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07549 uniprotkb:P39968 intact:EBI-22078|uniprotkb:D6VRM7|ensemblfungi:YDL123W intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W psi-mi:sna4_yeast(display_long)|uniprotkb:YDL123W(locus name)|uniprotkb:SNA4(gene name)|psi-mi:SNA4(display_short) psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344863|imex:IM-14275-2812 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010160.1|sgd:S000002281|dip:DIP-2816N|ensemblfungi:YDL123W(gene)|ensemblfungi:YDL123W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000612(Protein of unknown function UPF0057)|mint:Q07549 sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N psi-mi:"MI:0469"(intact) crc64:3B9378FD5EDDFA5A crc64:B2E75774B47E5933 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FYmk+8JkkE8m9CdHoTlaoPRxZtU559292 rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292 intact-crc:3D4453B718890666|rigid:7D5r66mKmaUb7fVUNO8VLf2NVuQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07549 uniprotkb:P41807 intact:EBI-22078|uniprotkb:D6VRM7|ensemblfungi:YDL123W intact:EBI-20281|uniprotkb:D6W446|ensemblfungi:YPR036W psi-mi:sna4_yeast(display_long)|uniprotkb:YDL123W(locus name)|uniprotkb:SNA4(gene name)|psi-mi:SNA4(display_short) psi-mi:vath_yeast(display_long)|uniprotkb:YP3085.02(orf name)|uniprotkb:VMA13(gene name)|psi-mi:VMA13(display_short)|uniprotkb:CLS11(gene name synonym)|uniprotkb:YPR036W(locus name)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 54 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344874|imex:IM-14275-2813 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010160.1|sgd:S000002281|dip:DIP-2816N|ensemblfungi:YDL123W(gene)|ensemblfungi:YDL123W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000612(Protein of unknown function UPF0057)|mint:Q07549 refseq:NP_015361.1|sgd:S000006240|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|rcsb pdb:1HO8|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YPR036W(gene)|ensemblfungi:YPR036W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|dip:DIP-6640N|mint:P41807 psi-mi:"MI:0469"(intact) crc64:3B9378FD5EDDFA5A crc64:54131FF9C2C87594 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FYmk+8JkkE8m9CdHoTlaoPRxZtU559292 rogid:kEXWvOsnTk0WdgGOny+mufz4lTo559292 intact-crc:BE2BB109FDA28064|rigid:PCHEqMsSnbYe54VJBZBEUsspjaw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07549 uniprotkb:P53191 intact:EBI-22078|uniprotkb:D6VRM7|ensemblfungi:YDL123W intact:EBI-13400|uniprotkb:E9P8Z2|uniprotkb:D6VUB4|ensemblfungi:YGL023C psi-mi:sna4_yeast(display_long)|uniprotkb:YDL123W(locus name)|uniprotkb:SNA4(gene name)|psi-mi:SNA4(display_short) psi-mi:pib2_yeast(display_long)|uniprotkb:PIB2(gene name)|psi-mi:PIB2(display_short)|uniprotkb:YGL023C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344885|imex:IM-14275-2814 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010160.1|sgd:S000002281|dip:DIP-2816N|ensemblfungi:YDL123W(gene)|ensemblfungi:YDL123W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000612(Protein of unknown function UPF0057)|mint:Q07549 refseq:NP_011492.3|sgd:S000002991|ensemblfungi:YGL023C(gene)|ensemblfungi:YGL023C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|mint:P53191|dip:DIP-6378N psi-mi:"MI:0469"(intact) crc64:3B9378FD5EDDFA5A crc64:512E9B873E6E0164 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FYmk+8JkkE8m9CdHoTlaoPRxZtU559292 rogid:3T1+dWkNV7dfKQf0/9hJkjQbRW4559292 intact-crc:D19B7B5F32C03B79|rigid:ls3Uv61VL9xI7HPwi45/BHMAvAQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53290 uniprotkb:Q07549 intact:EBI-7962|uniprotkb:D6VUU7|ensemblfungi:YGR163W intact:EBI-22078|uniprotkb:D6VRM7|ensemblfungi:YDL123W psi-mi:gtr2_yeast(display_long)|uniprotkb:YGR163W(locus name)|uniprotkb:GTR2(gene name)|psi-mi:GTR2(display_short) psi-mi:sna4_yeast(display_long)|uniprotkb:YDL123W(locus name)|uniprotkb:SNA4(gene name)|psi-mi:SNA4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344896|imex:IM-14275-2815 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003395|refseq:NP_011679.3|mint:P53290|dip:DIP-4521N|ensemblfungi:YGR163W(gene)|ensemblfungi:YGR163W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000785"(chromatin)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039400|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 refseq:NP_010160.1|sgd:S000002281|dip:DIP-2816N|ensemblfungi:YDL123W(gene)|ensemblfungi:YDL123W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000612(Protein of unknown function UPF0057)|mint:Q07549 psi-mi:"MI:0469"(intact) crc64:0A0D16C81F73184D crc64:3B9378FD5EDDFA5A figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+b9bPvzin/YUc5fOZZVCcFu/GEM559292 rogid:FYmk+8JkkE8m9CdHoTlaoPRxZtU559292 intact-crc:33A0285B8FB464B1|rigid:sYRIggILl6Ch/wtNVuBxg1Ktlvg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00582 uniprotkb:Q07549 intact:EBI-7954|uniprotkb:D6W0G3|ensemblfungi:YML121W intact:EBI-22078|uniprotkb:D6VRM7|ensemblfungi:YDL123W psi-mi:gtr1_yeast(display_long)|uniprotkb:YM7056.05(orf name)|uniprotkb:YML121W(locus name)|uniprotkb:GTR1(gene name)|psi-mi:GTR1(display_short) psi-mi:sna4_yeast(display_long)|uniprotkb:YDL123W(locus name)|uniprotkb:SNA4(gene name)|psi-mi:SNA4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344907|imex:IM-14275-2816 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013585.1|sgd:S000004590|mint:Q00582|dip:DIP-1358N|ensemblfungi:YML121W(gene)|ensemblfungi:YML121W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006348"|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039397|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 refseq:NP_010160.1|sgd:S000002281|dip:DIP-2816N|ensemblfungi:YDL123W(gene)|ensemblfungi:YDL123W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000612(Protein of unknown function UPF0057)|mint:Q07549 psi-mi:"MI:0469"(intact) crc64:B79CE7FE7AD2FDBE crc64:3B9378FD5EDDFA5A figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5LJU5zMF4NDDY9Bmndu0Q+JIm54559292 rogid:FYmk+8JkkE8m9CdHoTlaoPRxZtU559292 intact-crc:5730C65DFB841210|rigid:R4Z4NEWbhH+g8pyMewbMW/uITps false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07549 uniprotkb:Q02205 intact:EBI-22078|uniprotkb:D6VRM7|ensemblfungi:YDL123W intact:EBI-27062|uniprotkb:D6VX73|ensemblfungi:YKR007W psi-mi:sna4_yeast(display_long)|uniprotkb:YDL123W(locus name)|uniprotkb:SNA4(gene name)|psi-mi:SNA4(display_short) psi-mi:meh1_yeast(display_long)|uniprotkb:GSE complex subunit 2(gene name synonym)|uniprotkb:EGO complex subunit 1(gene name synonym)|uniprotkb:YKR007W(locus name)|uniprotkb:YK106(orf name)|uniprotkb:MEH1(gene name)|psi-mi:MEH1(display_short)|uniprotkb:EGO1(gene name synonym)|uniprotkb:GSE2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344918|imex:IM-14275-2817 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010160.1|sgd:S000002281|dip:DIP-2816N|ensemblfungi:YDL123W(gene)|ensemblfungi:YDL123W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000612(Protein of unknown function UPF0057)|mint:Q07549 sgd:S000001715|refseq:NP_012932.1|mint:Q02205|dip:DIP-1922N|ensemblfungi:YKR007W(gene)|ensemblfungi:YKR007W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0005829"(cytosol)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007040"(lysosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR028209|rcsb pdb:4XPM|rcsb pdb:6JWP psi-mi:"MI:0469"(intact) crc64:3B9378FD5EDDFA5A crc64:995DD1E68331D050 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FYmk+8JkkE8m9CdHoTlaoPRxZtU559292 rogid:73a6e5W5wQixGg2aGXDo4A6NR2s559292 intact-crc:68450CE0EC1C2C0A|rigid:gMh8qT5qQTd9fvrTchhcM6g1ATk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92331 uniprotkb:Q07549 intact:EBI-20483|uniprotkb:Q08483|uniprotkb:D6W2D1|uniprotkb:E9P8U6|ensemblfungi:YOR069W intact:EBI-22078|uniprotkb:D6VRM7|ensemblfungi:YDL123W psi-mi:vps5_yeast(display_long)|uniprotkb:VPS5(gene name)|psi-mi:VPS5(display_short)|uniprotkb:GRD2(gene name synonym)|uniprotkb:PEP10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 5(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 10(gene name synonym)|uniprotkb:VPT5(gene name synonym)|uniprotkb:YOR29-20(orf name)|uniprotkb:YOR069W(locus name) psi-mi:sna4_yeast(display_long)|uniprotkb:YDL123W(locus name)|uniprotkb:SNA4(gene name)|psi-mi:SNA4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344929|imex:IM-14275-2818 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014712.2|sgd:S000005595|ensemblfungi:YOR069W(gene)|ensemblfungi:YOR069W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0005768"(endosome)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|interpro:IPR001683(Phox-like)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028648|interpro:IPR035803|interpro:IPR036871|interpro:IPR037868|dip:DIP-1740N|mint:Q92331 refseq:NP_010160.1|sgd:S000002281|dip:DIP-2816N|ensemblfungi:YDL123W(gene)|ensemblfungi:YDL123W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000612(Protein of unknown function UPF0057)|mint:Q07549 psi-mi:"MI:0469"(intact) - crc64:3B9378FD5EDDFA5A figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5aPSkQUJV1sfIc9Ql+wMP74Y3QI559292 rogid:FYmk+8JkkE8m9CdHoTlaoPRxZtU559292 intact-crc:1DEF1606E6687679|rigid:KAIeJl0cSh30R3SI9/qr33LurSQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07623 uniprotkb:P15496 intact:EBI-32695|uniprotkb:D6VRE1|ensemblfungi:YDL213C intact:EBI-8902|ensemblfungi:YPL117C|uniprotkb:D6W3Q1 psi-mi:nop6_yeast(display_long)|uniprotkb:NOP6(gene name)|psi-mi:NOP6(display_short)|uniprotkb:D1018(orf name)|uniprotkb:YDL213C(locus name) psi-mi:idi1_yeast(display_long)|uniprotkb:Isopentenyl pyrophosphate isomerase(gene name synonym)|uniprotkb:IDI1(gene name)|psi-mi:IDI1(display_short)|uniprotkb:BOT2(gene name synonym)|uniprotkb:YPL117C(locus name)|uniprotkb:LPH10C(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344940|imex:IM-14275-2819 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010068.1|sgd:S000002372|dip:DIP-1807N|mint:Q07623|ensemblfungi:YDL213C(gene)|ensemblfungi:YDL213C_mRNA(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034228|interpro:IPR035979|rcsb pdb:2MZJ ensemblfungi:YPL117C(gene)|ensemblfungi:YPL117C_mRNA(transcript)|go:"GO:0004452"(isopentenyl-diphosphate delta-isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009240"(isopentenyl diphosphate biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0045337"(farnesyl diphosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050992"(dimethylallyl diphosphate biosynthetic process)|reactome:R-SCE-191273|refseq:NP_015208.1|sgd:S000006038|interpro:IPR011876(Isopentenyl-diphosphate delta-isomerase, type 1)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|mint:P15496 psi-mi:"MI:0469"(intact) crc64:2FB6E4C4BB1542B3 - figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:s3xgDQZrRxBQ/rjoqVnf1HmBdgA559292 rogid:KQ9qSb2grQ4DQip7atYPeCwp5QM559292 intact-crc:B5BAC0672166B862|rigid:lL0yqReQChTBHe2bqBBkE5fW+Uo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07623 uniprotkb:P24783 intact:EBI-32695|uniprotkb:D6VRE1|ensemblfungi:YDL213C intact:EBI-5602|uniprotkb:Q05456|uniprotkb:D6W169|ensemblfungi:YNL112W psi-mi:nop6_yeast(display_long)|uniprotkb:NOP6(gene name)|psi-mi:NOP6(display_short)|uniprotkb:D1018(orf name)|uniprotkb:YDL213C(locus name) psi-mi:dbp2_yeast(display_long)|uniprotkb:DBP2(gene name)|psi-mi:DBP2(display_short)|uniprotkb:YNL112W(locus name)|uniprotkb:N1945(orf name)|uniprotkb:DEAD box protein 2(gene name synonym)|uniprotkb:p68-like protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344951|imex:IM-14275-2820 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010068.1|sgd:S000002372|dip:DIP-1807N|mint:Q07623|ensemblfungi:YDL213C(gene)|ensemblfungi:YDL213C_mRNA(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034228|interpro:IPR035979|rcsb pdb:2MZJ sgd:S000005056|refseq:NP_014287.3|dip:DIP-2438N|mint:P24783|ensemblfungi:YNL112W(gene)|ensemblfungi:YNL112W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-3899300|reactome:R-SCE-9018519 psi-mi:"MI:0469"(intact) crc64:2FB6E4C4BB1542B3 crc64:30FE3D4C7E653120 figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:s3xgDQZrRxBQ/rjoqVnf1HmBdgA559292 rogid:BYs6atLcoqsO8/vwO7G5hMdrHyI559292 intact-crc:C1D5F311C7D9FB8A|rigid:l//VI8S+VZZ5lm6psn5cyDY1dtA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32495 uniprotkb:Q07623 intact:EBI-12014|ensemblfungi:YDL208W|uniprotkb:D6VRE6 intact:EBI-32695|uniprotkb:D6VRE1|ensemblfungi:YDL213C psi-mi:nhp2_yeast(display_long)|uniprotkb:NHP2(gene name)|psi-mi:NHP2(display_short)|uniprotkb:YDL208W(locus name)|uniprotkb:D1045(orf name)|uniprotkb:H/ACA snoRNP protein NHP2(gene name synonym)|uniprotkb:High mobility group-like nuclear protein 2(gene name synonym) psi-mi:nop6_yeast(display_long)|uniprotkb:NOP6(gene name)|psi-mi:NOP6(display_short)|uniprotkb:D1018(orf name)|uniprotkb:YDL213C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344962|imex:IM-14275-2821 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDL208W(gene)|ensemblfungi:YDL208W_mRNA(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000493"(box H/ACA snoRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|rcsb pdb:2LBW|rcsb pdb:2LBX|refseq:NP_010073.2|sgd:S000002367|mint:P32495|dip:DIP-5134N refseq:NP_010068.1|sgd:S000002372|dip:DIP-1807N|mint:Q07623|ensemblfungi:YDL213C(gene)|ensemblfungi:YDL213C_mRNA(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034228|interpro:IPR035979|rcsb pdb:2MZJ psi-mi:"MI:0469"(intact) crc64:008188132B494E5D crc64:2FB6E4C4BB1542B3 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p5AQTuMF3Vvdu6HWSTYjdjjE1Vs559292 rogid:s3xgDQZrRxBQ/rjoqVnf1HmBdgA559292 intact-crc:A83ECDA32CCC0F9F|rigid:uEQp8MIGs7y5zm8WvW2lwEZVqIY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07623 uniprotkb:P53874 intact:EBI-32695|uniprotkb:D6VRE1|ensemblfungi:YDL213C intact:EBI-19873|uniprotkb:D6W101|ensemblfungi:YNL186W psi-mi:nop6_yeast(display_long)|uniprotkb:NOP6(gene name)|psi-mi:NOP6(display_short)|uniprotkb:D1018(orf name)|uniprotkb:YDL213C(locus name) psi-mi:ubp10_yeast(display_long)|uniprotkb:UBP10(gene name)|psi-mi:UBP10(display_short)|uniprotkb:YNL186W(locus name)|uniprotkb:N1619(orf name)|uniprotkb:Ubiquitin-specific-processing protease 10(gene name synonym)|uniprotkb:Deubiquitinating enzyme 10(gene name synonym)|uniprotkb:Disrupter of telomere silencing protein 4(gene name synonym)|uniprotkb:Ubiquitin thioesterase 10(gene name synonym)|uniprotkb:DOT4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344973|imex:IM-14275-2822 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010068.1|sgd:S000002372|dip:DIP-1807N|mint:Q07623|ensemblfungi:YDL213C(gene)|ensemblfungi:YDL213C_mRNA(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034228|interpro:IPR035979|rcsb pdb:2MZJ refseq:NP_014213.2|sgd:S000005130|ensemblfungi:YNL186W(gene)|ensemblfungi:YNL186W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0043596"(nuclear replication fork)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|rcsb pdb:6RR0|dip:DIP-6664N|mint:P53874 psi-mi:"MI:0469"(intact) crc64:2FB6E4C4BB1542B3 - figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:s3xgDQZrRxBQ/rjoqVnf1HmBdgA559292 rogid:Z1rRAI9RLgHeGd7QwLbrf51v5LY559292 intact-crc:11C3D495E1C654C2|rigid:Bf3+fkQopmM3iijhEbYcLpgaKOU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P10823 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344984|imex:IM-14275-2823 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) - crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:55395BD9F0D37E12|rigid:MjHP4MgZQkd/rG/f8ZdcrlgCPhw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P17064 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-2047850|uniprotkb:D3DLV9|ensemblfungi:YER056C psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:fcy2_yeast(display_long)|uniprotkb:Cytosine/purine transport protein FCY2(gene name synonym)|uniprotkb:Fluorocytosine resistance protein 2(gene name synonym)|uniprotkb:YER056C(locus name)|uniprotkb:FCY2(gene name)|psi-mi:FCY2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6344995|imex:IM-14275-2824 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_010976.1|sgd:S000000858|dip:DIP-7593N|mint:P17064|ensemblfungi:YER056C(gene)|ensemblfungi:YER056C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015205"(nucleobase transmembrane transporter activity)|go:"GO:0015212"(cytidine transmembrane transporter activity)|go:"GO:0015856"(cytosine transport)|go:"GO:0015861"(cytidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:0072530"(purine-containing compound transmembrane transport)|interpro:IPR001248(Permease for cytosine/purines, uracil, thiamine, allantoin)|interpro:IPR012681(Nucleobase cation symporter-1, NCS1)|interpro:IPR026030 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:797s9w2xSSBhW0uTLcFEESToqgg559292 intact-crc:B93C0891D84FA543|rigid:tf7Kw9PjBvz5A0ga6Xg2ZZG4WwA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:Q07651 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345006|imex:IM-14275-2825 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:7DF2CFA20C4FCD7C|rigid:cTwztIkHIRtq1s7iNLaNj+k0z/M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P23585 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-2054100|uniprotkb:D6VZI5|ensemblfungi:YMR011W psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:hxt2_yeast(display_long)|uniprotkb:YM8270.15(orf name)|uniprotkb:YMR011W(locus name)|uniprotkb:HXT2(gene name)|psi-mi:HXT2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345017|imex:IM-14275-2826 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_013724.1|sgd:S000004613|dip:DIP-7912N|mint:P23585|ensemblfungi:YMR011W(gene)|ensemblfungi:YMR011W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:d4PFyh6BHnB/WnnF3A4GF3EphgY559292 intact-crc:D21F8680F064BEF5|rigid:izop4pYJLVt+p7zrFOJeVWcfUso false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P25619 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345028|imex:IM-14275-2827 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) - crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:55414421CF1574B2|rigid:gl2croUd09IX2Kdnfwb72ufa8yo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28321 uniprotkb:Q07651 intact:EBI-26790|uniprotkb:D6VXJ4|ensemblfungi:YKL094W intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:mgll_yeast(display_long)|uniprotkb:YJU3(gene name)|psi-mi:YJU3(display_short)|uniprotkb:Monoacylglycerol hydrolase(gene name synonym)|uniprotkb:Monoacylglycerol lipase(gene name synonym)|uniprotkb:Serine hydrolase YJU3(gene name synonym)|uniprotkb:YKL441(orf name)|uniprotkb:YKL094W(locus name)|uniprotkb:Fatty acid ethyl ester hydrolase(gene name synonym) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345039|imex:IM-14275-2828 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022742|refseq:NP_012829.1|sgd:S000001577|mint:P28321|interpro:IPR029058|ensemblfungi:YKL094W(gene)|ensemblfungi:YKL094W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0071944"(cell periphery)|rcsb pdb:4ZWN|rcsb pdb:4ZXF refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IHpY1aez3MG+bn7bThCBdvE6KMw559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:0C428A3929084736|rigid:/430iGR/+x43zHf5VJ3ydXlwXdo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30605 uniprotkb:Q07651 intact:EBI-2050956|uniprotkb:D6VTB9|ensemblfungi:YDR497C intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:itr1_yeast(display_long)|uniprotkb:D9719.3(orf name)|uniprotkb:YDR497C(locus name)|uniprotkb:ITR1(gene name)|psi-mi:ITR1(display_short) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345050|imex:IM-14275-2829 author score:99.26 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010785.1|sgd:S000002905|dip:DIP-7406N|mint:P30605|ensemblfungi:YDR497C(gene)|ensemblfungi:YDR497C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.26|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GgtK4YFe7ZCZcmVpV5q1KY2F0Ds559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:039D4B7CB482B87E|rigid:xWP+TDL5LLnYkEzw7JNxUDYn81Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:Q07651 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345061|imex:IM-14275-2830 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:66FC460EAF04DEA6|rigid:RmhqJ/cR56pCBse6xZ1QCIc+rZc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32568 uniprotkb:Q07651 intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345072|imex:IM-14275-2831 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:A512973D0C535885|rigid:qzQXtZII5dqA81bn2e5w11wloQ8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33302 uniprotkb:Q07651 intact:EBI-13038|uniprotkb:D6W2L0|ensemblfungi:YOR153W intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:pdr5_yeast(display_long)|uniprotkb:PDR5(gene name)|psi-mi:PDR5(display_short)|uniprotkb:LEM1(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 5(gene name synonym)|uniprotkb:Suppressor of toxicity of sporidesmin(gene name synonym)|uniprotkb:YOR153W(locus name) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345083|imex:IM-14275-2832 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005679|refseq:NP_014796.3|mint:P33302|dip:DIP-6776N|ensemblfungi:YOR153W(gene)|ensemblfungi:YOR153W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR029481|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926 refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Sd6SJWf6B0rDZnLVaPHyvr4lhew559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:47C93CA086F834E8|rigid:5tq54FIsTgNDlgW723zt6yO03Es false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P33413 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-2060312|uniprotkb:D3DKP5|ensemblfungi:YHL016C psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:dur3_yeast(display_long)|uniprotkb:DUR3(gene name)|psi-mi:DUR3(display_short)|uniprotkb:YHL016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345094|imex:IM-14275-2833 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) interpro:IPR031155|refseq:NP_011847.1|sgd:S000001008|interpro:IPR001734(Na+/solute symporter)|interpro:IPR038377|mint:P33413|ensemblfungi:YHL016C(gene)|ensemblfungi:YHL016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0015204"(urea transmembrane transporter activity)|go:"GO:0015489"(putrescine transmembrane transporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015840"(urea transport)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:oTFsdtOngA3q5wCbhK/fpVlIsz0559292 intact-crc:912419743F23E75E|rigid:DDnfwGvqHFLAPNw3f9Dd6d8ygK8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35735 uniprotkb:Q07651 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345105|imex:IM-14275-2834 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:B6D1DBF9B94199E7|rigid:OuSSx7XvkNim9Tdqhnbv84ZUxFI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P36027 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345116|imex:IM-14275-2835 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:B53FCD53C710EF50|rigid:goCPhcQQxVF7TMbOjFKmxhG8CYY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P36169 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-26550|uniprotkb:D6VXG1|uniprotkb:Q86ZT0|ensemblfungi:YKR100C psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:skg1_yeast(display_long)|uniprotkb:YKR099C-A(orf name)|uniprotkb:YKR100C(locus name)|uniprotkb:SKG1(gene name)|psi-mi:SKG1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345127|imex:IM-14275-2836 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_013026.2|sgd:S000001808|mint:P36169|dip:DIP-4605N|ensemblfungi:YKR100C(gene)|ensemblfungi:YKR100C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0033101"(cellular bud membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:5M0958TOQRgRN0sv3MGTqI/ee2k559292 intact-crc:7857C87DB08827D4|rigid:dgzQ87HNwk+T6HrTJlkB03upPiU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38143 uniprotkb:Q07651 intact:EBI-7863|uniprotkb:D6VQP0|ensemblfungi:YBR244W intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:gpx2_yeast(display_long)|uniprotkb:GPX2(gene name)|psi-mi:GPX2(display_short)|uniprotkb:Glutathione peroxidase homolog 2(gene name synonym)|uniprotkb:YBR1632(orf name)|uniprotkb:YBR244W(locus name) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345138|imex:IM-14275-2837 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000448|refseq:NP_009803.3|mint:P38143|dip:DIP-8180N|ensemblfungi:YBR244W(gene)|ensemblfungi:YBR244W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR029759|interpro:IPR029760|interpro:IPR036249|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661 refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cL8rm6IttRi0QYzWVEooubWkZN8559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:0F63A1AF28CD1814|rigid:tB5RG5ebWASEM9zhfiI9DW3/mWU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P38196 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-7158|uniprotkb:D6VPV6|ensemblfungi:YBL042C psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:fui1_yeast(display_long)|uniprotkb:FUI1(gene name)|psi-mi:FUI1(display_short)|uniprotkb:YBL0406(orf name)|uniprotkb:YBL042C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345149|imex:IM-14275-2838 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_009511.1|sgd:S000000138|dip:DIP-1321N|mint:P38196|ensemblfungi:YBL042C(gene)|ensemblfungi:YBL042C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015205"(nucleobase transmembrane transporter activity)|go:"GO:0015213"(uridine transmembrane transporter activity)|go:"GO:0015851"(nucleobase transport)|go:"GO:0015862"(uridine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR001248(Permease for cytosine/purines, uracil, thiamine, allantoin)|interpro:IPR012681(Nucleobase cation symporter-1, NCS1) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:ESbe5XfGhfMFQk2sgjqm+duIHyg559292 intact-crc:738B06C95241B265|rigid:iGC/i1O9c9zkIwuCUugRuQ2T5sQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P38234 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345160|imex:IM-14275-2839 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 intact-crc:57711710042E7A99|rigid:mBcSghyGfzHT1FdJ12a9VHzoSuY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38695 uniprotkb:Q07651 intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345171|imex:IM-14275-2840 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) crc64:6906721BAC1A5F87 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:C806931495D428CF|rigid:ReSZCIDD7flT6ywJqNzZn49cyXM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P39719 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-20703|uniprotkb:Q05165|uniprotkb:D6VPG5|ensemblfungi:YAL053W psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:flc2_yeast(display_long)|uniprotkb:YAL053W(locus name)|uniprotkb:FLC2(gene name)|psi-mi:FLC2(display_short)|uniprotkb:FAD transporter 2(gene name synonym)|uniprotkb:TRP-like ion channel FLC2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345182|imex:IM-14275-2841 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_009348.2|sgd:S000000049|ensemblfungi:YAL053W(gene)|ensemblfungi:YAL053W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241|go:"GO:0055085"(transmembrane transport)|dip:DIP-6708N|mint:P39719 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:NOmMW54DNa0o7vM945DlZgVUy44559292 intact-crc:5C1F1D42AE11FED1|rigid:KyK8+ib0W++U5pMnasR2IzfGgEs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40260 uniprotkb:Q07651 intact:EBI-10714|ensemblfungi:YGR121C|uniprotkb:D6VUQ2 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:mep1_yeast(display_long)|uniprotkb:MEP1(gene name)|psi-mi:MEP1(display_short)|uniprotkb:YGR121C(locus name)|uniprotkb:G6331(orf name)|uniprotkb:AMT1(gene name synonym) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345193|imex:IM-14275-2842 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR121C(gene)|ensemblfungi:YGR121C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|sgd:S000003353|refseq:NP_011636.3|mint:P40260|dip:DIP-5530N refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VnoBl5jhQD24N0SbCLv68HCwl1U559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:A0529656C080A19C|rigid:z2yRTfeqNQo7KQtp/dWxBkqbWGU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P40485 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-25172|uniprotkb:D6VVI2|ensemblfungi:YIL105C psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:slm1_yeast(display_long)|uniprotkb:TORC2 effector protein SLM1(gene name synonym)|uniprotkb:Synthetic lethal with MSS4 protein 1(gene name synonym)|uniprotkb:YIL105C(locus name)|uniprotkb:SLM1(gene name)|psi-mi:SLM1(display_short)|uniprotkb:LIT2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345204|imex:IM-14275-2843 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_012161.1|sgd:S000001367|mint:P40485|dip:DIP-1353N|ensemblfungi:YIL105C(gene)|ensemblfungi:YIL105C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070941"(eisosome assembly)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR033191|interpro:IPR043453|rcsb pdb:3NSU|rcsb pdb:4A5K|rcsb pdb:4A6F|rcsb pdb:4A6H|rcsb pdb:4A6K psi-mi:"MI:0469"(intact) - crc64:849C82CC0960014B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:f0Gtntpff7Oav37jlVaggG2VI30559292 intact-crc:1B7FD290B6600E50|rigid:TYT+R5zt74sgZMtVgGgfPzHeLW4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P40581 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-7869|ensemblfungi:YIR037W|uniprotkb:D6VVW8 psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:gpx3_yeast(display_long)|uniprotkb:HYR1(gene name)|psi-mi:HYR1(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:Hydrogen peroxide resistance protein 1(gene name synonym)|uniprotkb:Oxidant receptor peroxidase 1(gene name synonym)|uniprotkb:Phospholipid hydroperoxide glutathione peroxidase 3(gene name synonym)|uniprotkb:GPX3(gene name synonym)|uniprotkb:YIR037W(locus name)|uniprotkb:Glutathione peroxidase homolog 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345215|imex:IM-14275-2844 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_012303.1|sgd:S000001476|ensemblfungi:YIR037W(gene)|ensemblfungi:YIR037W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR029760|interpro:IPR036249|rcsb pdb:3CMI|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661|interpro:IPR029759|mint:P40581|dip:DIP-1275N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:Pi8aaZEVc33CTMPyaM0mpscvLU4559292 intact-crc:D19674F24BA2D221|rigid:Ee7TjcyQRH9l22RLezrU5oy0gM8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40994 uniprotkb:Q07651 intact:EBI-2824|uniprotkb:D6W2F5|ensemblfungi:YOR094W intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:arf3_yeast(display_long)|uniprotkb:ARF3(gene name)|psi-mi:ARF3(display_short)|uniprotkb:YOR3172W(orf name)|uniprotkb:YOR094W(locus name) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345226|imex:IM-14275-2845 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014737.1|sgd:S000005620|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P40994|interpro:IPR041838|ensemblfungi:YOR094W(gene)|ensemblfungi:YOR094W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010513"(positive regulation of phosphatidylinositol biosynthetic process)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0036267"(invasive filamentous growth)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:uC+fupPUZajD7m7pLEO/K0Kuudo559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:57373F940F974CD9|rigid:bwF7NABQ/7EvNkl+m/elCVaobjo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P47072 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-25803|uniprotkb:D6VWG2|uniprotkb:P47071|uniprotkb:Q86ZR5|ensemblfungi:YJL016W psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:yjb6_yeast(display_long)|uniprotkb:J1320(orf name)|uniprotkb:J1326(orf name)|uniprotkb:YJL017W(orf name)|uniprotkb:YJL016W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345237|imex:IM-14275-2846 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) sgd:S000003553|refseq:NP_012518.2|mint:P47072|dip:DIP-4907N|ensemblfungi:YJL016W(gene)|ensemblfungi:YJL016W_mRNA(transcript)|go:"GO:0005737"(cytoplasm) psi-mi:"MI:0469"(intact) - crc64:21D1541BCFEFDFF6 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:XRf3g3pILUK7J16Tol90s1MoEY4559292 intact-crc:B115DAA8BEC78D41|rigid:ljpFa41/rxAxKcp/4NC/ZaYmKCQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P50276 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345248|imex:IM-14275-2847 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:368E6A722A28898C|rigid:tK3jVBHfC17QHGDPUazWnNIhqf0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P53139 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-23908|uniprotkb:D6VU38|ensemblfungi:YGL108C psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:ygk8_yeast(display_long)|uniprotkb:G3070(orf name)|uniprotkb:YGL108C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345259|imex:IM-14275-2848 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) sgd:S000003076|refseq:NP_011407.3|mint:P53139|ensemblfungi:YGL108C(gene)|ensemblfungi:YGL108C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:6rg2zcMN57peeKKy/RolIDcNaLc559292 intact-crc:01357B8BE170AE7E|rigid:ll8++R90Y7Nt4N0CUGG6bF5PFxU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P53278 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345270|imex:IM-14275-2849 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome) psi-mi:"MI:0469"(intact) - crc64:D482327C9274C026 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292 intact-crc:EE8D5BEF4EF117D7|rigid:BVK2ZaUN8l7pdqSGfFhgXgHgi7o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P53283 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345281|imex:IM-14275-2850 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 intact-crc:42A25BC7586EDD0A|rigid:tHTGHUQbq7hysft1C2k4coyByLI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53390 uniprotkb:Q07651 intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345292|imex:IM-14275-2851 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) crc64:2309338F36D96258 - figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:E02EEDBA937DB12D|rigid:y4J3E6sp4SZTAO5v3u/LfNQbjyg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:P53885 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-29022|uniprotkb:D6W111|ensemblfungi:YNL173C psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:mdg1_yeast(display_long)|uniprotkb:YNL173C(locus name)|uniprotkb:N1673(orf name)|uniprotkb:Multicopy suppressor of defective G-protein 1(gene name synonym)|uniprotkb:MDG1(gene name)|psi-mi:MDG1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345303|imex:IM-14275-2852 author score:99.26 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_014226.1|sgd:S000005117|dip:DIP-2777N|mint:P53885|ensemblfungi:YNL173C(gene)|ensemblfungi:YNL173C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0080090"(regulation of primary metabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR032640|reactome:R-SCE-1632852|reactome:R-SCE-380972 psi-mi:"MI:0469"(intact) - crc64:1B29D0D6D0A5D1C3 figure legend:tables S3 and S4|author-confidence:99.26|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:LKSD5QTVw1QiteRAnAjoQgdc1Aw559292 intact-crc:DE0232BCD7571DB9|rigid:xe6OFkxS7JSEyWoK+zSn9JmB+Uw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02785 uniprotkb:Q07651 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345314|imex:IM-14275-2853 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:FB7BE911DD0CC0B2|rigid:PdDNbcVFtXNwb4TAsdiwkwxZDbQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03088 uniprotkb:Q07651 intact:EBI-36005|uniprotkb:D6W3Y1|ensemblfungi:YPL032C intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:svl3_yeast(display_long)|uniprotkb:SVL3(gene name)|psi-mi:SVL3(display_short)|uniprotkb:P7102.17(orf name)|uniprotkb:YPL032C(locus name) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345325|imex:IM-14275-2854 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015293.1|sgd:S000005953|mint:Q03088|dip:DIP-2723N|ensemblfungi:YPL032C(gene)|ensemblfungi:YPL032C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0071944"(cell periphery)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR013752(Ketopantoate reductase ApbA/PanE, C-terminal) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) crc64:1658119E0A436B11 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:bGp8JMfYxtflXmXS3c+ayVrRGms559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:030921437E40CD39|rigid:kbdrh7nR8Hh74aHjT8KTEE4jjNs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:Q03640 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345336|imex:IM-14275-2855 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) - crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:6BE66766A289AA9F|rigid:TGj87tgmp74kZv4Vc/mI87vUi3o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05812 uniprotkb:Q07651 intact:EBI-33150|uniprotkb:Q7LIF4|uniprotkb:D6VYL9|ensemblfungi:YLR219W intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:msc3_yeast(display_long)|uniprotkb:MSC3(gene name)|psi-mi:MSC3(display_short)|uniprotkb:YLR219W(locus name) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345347|imex:IM-14275-2856 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004209|refseq:NP_013320.1|mint:Q05812|dip:DIP-6321N|ensemblfungi:YLR219W(gene)|ensemblfungi:YLR219W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007131"(reciprocal meiotic recombination) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) crc64:1962D638DB602B71 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:xS8zCG9eHY8V0vNstOwUuTcI3Ao559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:D61D4A29CE0C7AB4|rigid:5Y54jeQkQe00IcQ7hQpRYPCloUM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:Q06170 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-35994|uniprotkb:D6VYW8|ensemblfungi:YLR326W psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:yl326_yeast(display_long)|uniprotkb:YLR326W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345358|imex:IM-14275-2857 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_013430.1|sgd:S000004318|mint:Q06170|dip:DIP-3995N|ensemblfungi:YLR326W(gene)|ensemblfungi:YLR326W_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR025187 psi-mi:"MI:0469"(intact) - crc64:724CD7833AA9B416 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:Ufkoj1kRp4Y9JTsgbL+3k8hzJyo559292 intact-crc:A8CC1283AF510413|rigid:j8u5gagd81rLBcaEj6TbEYQkXRo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06179 uniprotkb:Q07651 intact:EBI-32551|uniprotkb:D6VZ88|ensemblfungi:YLR454W intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:fmp27_yeast(display_long)|uniprotkb:FMP27(gene name)|psi-mi:FMP27(display_short)|uniprotkb:Found in mitochondrial proteome protein 27(gene name synonym)|uniprotkb:YLR454W(locus name) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345369|imex:IM-14275-2858 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013559.1|sgd:S000004446|dip:DIP-3005N|mint:Q06179|ensemblfungi:YLR454W(gene)|ensemblfungi:YLR454W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|interpro:IPR019409|interpro:IPR019415|interpro:IPR019439|interpro:IPR019441|interpro:IPR019443|interpro:IPR019449 refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:sTubG6TouVnqDZ9kBcxn06d8d9Q559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:A1CDA072F9E45E41|rigid:zZTyTyQw2fs3szEb5nYRsaPEsWU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06451 uniprotkb:Q07651 intact:EBI-34275|uniprotkb:D6W4F2|ensemblfungi:YPR156C intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:tpo3_yeast(display_long)|uniprotkb:TPO3(gene name)|psi-mi:TPO3(display_short)|uniprotkb:P9584.7(orf name)|uniprotkb:YPR156C(locus name) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345380|imex:IM-14275-2859 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015482.1|sgd:S000006360|mint:Q06451|dip:DIP-3907N|ensemblfungi:YPR156C(gene)|ensemblfungi:YPR156C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) crc64:D260ED161F800502 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oVpx7Bjk/mK2Q7+/j05tX3gHw7k559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:E25CF7871B4427FE|rigid:aQ490Q0GVOhIw/ifrX9KvVwrbqk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:Q07651 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345391|imex:IM-14275-2860 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:03BD20DE05206D3E|rigid:J5F7fXujCMzU471ou3EbqKs5dvc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07824 uniprotkb:Q07651 intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345402|imex:IM-14275-2861 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:FD13140F26197439|rigid:dKI1m13vdLNWDTr7rfztw6kkgwA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:Q08967 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-36673|uniprotkb:D6W3E9|ensemblfungi:YPL221W psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:flc1_yeast(display_long)|uniprotkb:FAD transporter 1(gene name synonym)|uniprotkb:FLC1(gene name)|psi-mi:FLC1(display_short)|uniprotkb:TRP-like ion channel protein FLC1(gene name synonym)|uniprotkb:Heme utilization factor 1(gene name synonym)|uniprotkb:Bypass of PAM1 protein 1(gene name synonym)|uniprotkb:HUF1(gene name synonym)|uniprotkb:YPL221W(locus name)|uniprotkb:BOP1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345413|imex:IM-14275-2862 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_015103.1|sgd:S000006142|mint:Q08967|dip:DIP-3965N|ensemblfungi:YPL221W(gene)|ensemblfungi:YPL221W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055085"(transmembrane transport)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:r6CcZGEjxHUk2w0iBUBvnAPaFd4559292 intact-crc:B43749E334FCA19F|rigid:JcGmdMODH0jfluxHa657td2FoTI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:Q12236 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-9844|intact:EBI-2935811|uniprotkb:D6W1W8|ensemblfungi:YOL100W psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:pkh2_yeast(display_long)|uniprotkb:YOL100W(locus name)|uniprotkb:HRC1081(orf name)|uniprotkb:PKH2(gene name)|psi-mi:PKH2(display_short)|uniprotkb:PKB-activating kinase homolog 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345424|imex:IM-14275-2863 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_014541.1|sgd:S000005460|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060211"("regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblfungi:YOL100W(gene)|ensemblfungi:YOL100W_mRNA(transcript)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039046|reactome:R-SCE-114604|reactome:R-SCE-1257604|reactome:R-SCE-165158|reactome:R-SCE-202424|reactome:R-SCE-2730905|reactome:R-SCE-389357|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0004672"(protein kinase activity)|reactome:R-SCE-392451|reactome:R-SCE-5218920|reactome:R-SCE-5218921|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-6804757|reactome:R-SCE-9634635|reactome:R-SCE-5625740|dip:DIP-6295N|mint:Q12236 psi-mi:"MI:0469"(intact) - crc64:BE0DD9D49AC2EBC3 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:KzJ+WGY+PylRDsK1olfak8IyuXM559292 intact-crc:67BB52820637ED10|rigid:aI0D26Oea/okYRdOzKsOaTtdel8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:Q12256 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345435|imex:IM-14275-2864 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 intact-crc:F07AC4B8D2EBD4D5|rigid:njQ/Qtje0rNxWsoHOO4EJZxDC+g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:Q12335 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345446|imex:IM-14275-2865 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) - crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:08211051630D2A19|rigid:jfxsECCQ1/cPZ56q2xqxcbTj/mQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:Q3E756 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-2044812|uniprotkb:D6VPX0|ensemblfungi:YBL029C-A psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:yb029_yeast(display_long)|uniprotkb:YBL029C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345457|imex:IM-14275-2866 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) sgd:S000007591|refseq:NP_076874.1|mint:Q3E756|ensemblfungi:YBL029C-A(gene)|ensemblfungi:YBL029C-A_mRNA(transcript)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:Y9LDkESr65DK5SLFNTw1dBKeqPc559292 intact-crc:6BAAA8BCBF4D6967|rigid:w/3ITgNPbVo9qSssI7dT/gnpG7Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06102 uniprotkb:Q07655 intact:EBI-12165|uniprotkb:D6VVP4|uniprotkb:Q6B233|ensemblfungi:YIL038C intact:EBI-31312|uniprotkb:D6VRD1|ensemblfungi:YDL224C psi-mi:not3_yeast(display_long)|uniprotkb:NOT3(gene name)|psi-mi:NOT3(display_short)|uniprotkb:YIL038C(locus name) psi-mi:whi4_yeast(display_long)|uniprotkb:WHI4(gene name)|psi-mi:WHI4(display_short)|uniprotkb:D0839(orf name)|uniprotkb:YDL224C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345468|imex:IM-14275-2867 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR038635|interpro:IPR040168|ensemblfungi:YIL038C(gene)|ensemblfungi:YIL038C_mRNA(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|refseq:NP_012226.3|sgd:S000001300|dip:DIP-2256N|mint:P06102 refseq:NP_010057.1|sgd:S000002383|dip:DIP-4321N|mint:Q07655|ensemblfungi:YDL224C(gene)|ensemblfungi:YDL224C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008361"(regulation of cell size)|go:"GO:0061157"(mRNA destabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979 psi-mi:"MI:0469"(intact) crc64:69B76694FCC6846F - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:EfakZPDNU3FZeI5+rnu7YV1UsCg559292 rogid:zPUzt32TQkMfrkafLvfsgHhZbYA559292 intact-crc:BE3083ECB220210D|rigid:sOAVzxSJ8HBHbqpm1Qga8+3UB2s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25655 uniprotkb:Q07655 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-31312|uniprotkb:D6VRD1|ensemblfungi:YDL224C psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:whi4_yeast(display_long)|uniprotkb:WHI4(gene name)|psi-mi:WHI4(display_short)|uniprotkb:D0839(orf name)|uniprotkb:YDL224C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345479|imex:IM-14275-2868 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 refseq:NP_010057.1|sgd:S000002383|dip:DIP-4321N|mint:Q07655|ensemblfungi:YDL224C(gene)|ensemblfungi:YDL224C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008361"(regulation of cell size)|go:"GO:0061157"(mRNA destabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979 psi-mi:"MI:0469"(intact) crc64:5B2AE15BCF95E009 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:zPUzt32TQkMfrkafLvfsgHhZbYA559292 intact-crc:FA21688E541B4898|rigid:PrckjPEn4MCLoPbLW0muLW1x/mU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07655 uniprotkb:P53829 intact:EBI-31312|uniprotkb:D6VRD1|ensemblfungi:YDL224C intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W psi-mi:whi4_yeast(display_long)|uniprotkb:WHI4(gene name)|psi-mi:WHI4(display_short)|uniprotkb:D0839(orf name)|uniprotkb:YDL224C(locus name) psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345490|imex:IM-14275-2869 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010057.1|sgd:S000002383|dip:DIP-4321N|mint:Q07655|ensemblfungi:YDL224C(gene)|ensemblfungi:YDL224C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008361"(regulation of cell size)|go:"GO:0061157"(mRNA destabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979 refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 psi-mi:"MI:0469"(intact) - crc64:F3DBABE6AD3C7F3C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zPUzt32TQkMfrkafLvfsgHhZbYA559292 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 intact-crc:B929BD73723DF800|rigid:1g6scDhrJmRhYanKuz0r+bmQ88I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07657 uniprotkb:P32458 intact:EBI-22083|uniprotkb:D6VRD0|ensemblfungi:YDL225W intact:EBI-4178|uniprotkb:D6VWP6|ensemblfungi:YJR076C psi-mi:shs1_yeast(display_long)|uniprotkb:YDL225W(locus name)|uniprotkb:Septation protein 7(gene name synonym)|uniprotkb:SHS1(gene name)|psi-mi:SHS1(display_short)|uniprotkb:SEP7(gene name synonym) psi-mi:cdc11_yeast(display_long)|uniprotkb:CDC11(gene name)|psi-mi:CDC11(display_short)|uniprotkb:PSL9(gene name synonym)|uniprotkb:YJR076C(locus name)|uniprotkb:J1833(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345501|imex:IM-14275-2870 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010056.1|sgd:S000002384|dip:DIP-5596N|ensemblfungi:YDL225W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010458"(exit from mitosis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043332"(mating projection tip)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061163"(endoplasmic reticulum polarization)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097271"(protein localization to bud neck)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|ensemblfungi:YDL225W(gene)|mint:Q07657 refseq:NP_012610.1|sgd:S000003837|dip:DIP-1656N|mint:P32458|ensemblfungi:YJR076C(gene)|ensemblfungi:YJR076C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:5AR1 psi-mi:"MI:0469"(intact) crc64:BDA2631061A278F9 crc64:5CFFD4CD1F6C57D4 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4A/dWGsbB5nAWr1kP+zTlT9B3z4559292 rogid:KRcNMx6EOTmvHb+6u15UrVoyb3s559292 intact-crc:FBC8CE39DDA9AAAE|rigid:P7mOcjYUSz4i2d3jDVr4DXrBY10 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07657 uniprotkb:Q07657 intact:EBI-22083|uniprotkb:D6VRD0|ensemblfungi:YDL225W intact:EBI-22083|uniprotkb:D6VRD0|ensemblfungi:YDL225W psi-mi:shs1_yeast(display_long)|uniprotkb:YDL225W(locus name)|uniprotkb:Septation protein 7(gene name synonym)|uniprotkb:SHS1(gene name)|psi-mi:SHS1(display_short)|uniprotkb:SEP7(gene name synonym) psi-mi:shs1_yeast(display_long)|uniprotkb:YDL225W(locus name)|uniprotkb:Septation protein 7(gene name synonym)|uniprotkb:SHS1(gene name)|psi-mi:SHS1(display_short)|uniprotkb:SEP7(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345512|imex:IM-14275-2871 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010056.1|sgd:S000002384|dip:DIP-5596N|ensemblfungi:YDL225W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010458"(exit from mitosis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043332"(mating projection tip)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061163"(endoplasmic reticulum polarization)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097271"(protein localization to bud neck)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|ensemblfungi:YDL225W(gene)|mint:Q07657 refseq:NP_010056.1|sgd:S000002384|dip:DIP-5596N|ensemblfungi:YDL225W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010458"(exit from mitosis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043332"(mating projection tip)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061163"(endoplasmic reticulum polarization)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097271"(protein localization to bud neck)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|ensemblfungi:YDL225W(gene)|mint:Q07657 psi-mi:"MI:0469"(intact) crc64:BDA2631061A278F9 crc64:BDA2631061A278F9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4A/dWGsbB5nAWr1kP+zTlT9B3z4559292 rogid:4A/dWGsbB5nAWr1kP+zTlT9B3z4559292 intact-crc:242B1A11560CF948|rigid:wPFWeiCNEH0mPJw2FgyOpHWIucc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07688 uniprotkb:Q07084 intact:EBI-34423|uniprotkb:D6VRC1|ensemblfungi:YDL235C intact:EBI-18184|uniprotkb:Q07909|uniprotkb:D6VY08|ensemblfungi:YLR006C psi-mi:ypd1_yeast(display_long)|uniprotkb:YPD1(gene name)|psi-mi:YPD1(display_short)|uniprotkb:Histidine-containing phosphotransfer protein YPD1(gene name synonym)|uniprotkb:Tyrosine phosphatase-dependent protein 1(gene name synonym)|uniprotkb:D0790(orf name)|uniprotkb:YDL235C(locus name) psi-mi:ssk1_yeast(display_long)|uniprotkb:YLR006C(locus name)|uniprotkb:SSK1(gene name)|psi-mi:SSK1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345523|imex:IM-14275-2872 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010046.1|sgd:S000002394|mint:Q07688|dip:DIP-5899N|ensemblfungi:YDL235C(gene)|ensemblfungi:YDL235C_mRNA(transcript)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007234"(osmosensory signaling via phosphorelay pathway)|go:"GO:0009927"(histidine phosphotransfer kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016772"(transferase activity, transferring phosphorus-containing groups)|go:"GO:0043424"(protein histidine kinase binding)|interpro:IPR008207("Signal transduction histidine kinase, phosphotransfer (Hpt) region")|interpro:IPR036641|rcsb pdb:1C02|rcsb pdb:1C03|rcsb pdb:1OXB|rcsb pdb:1OXK|rcsb pdb:1QSP|rcsb pdb:2R25|rcsb pdb:5KBX|rcsb pdb:6M7W refseq:NP_013106.1|sgd:S000003996|ensemblfungi:YLR006C(gene)|ensemblfungi:YLR006C_mRNA(transcript)|go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007234"(osmosensory signaling via phosphorelay pathway)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:1990315"(Mcs4 RR-MAPKKK complex)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|rcsb pdb:5KBX|dip:DIP-2437N|mint:Q07084 psi-mi:"MI:0469"(intact) crc64:4B923E621C57783D crc64:33B2DBB4FCF2528A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YN/TB6a79rhT0M1R09pLAyj/Xac559292 rogid:xmyX+JrLkDhsvw7i7m+FHfBWmV0559292 intact-crc:145F5B99E5A157F2|rigid:HazSyPP+a2TppSCg0sMWxDlzrwg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07788 uniprotkb:Q03370 intact:EBI-4980|uniprotkb:D6VRA9|ensemblfungi:YDL248W intact:EBI-36170|uniprotkb:D6VTA2|ensemblfungi:YDR479C psi-mi:cos7_yeast(display_long)|uniprotkb:COS7(gene name)|psi-mi:COS7(display_short)|uniprotkb:YDL248W(locus name) psi-mi:pex29_yeast(display_long)|uniprotkb:PEX29(gene name)|psi-mi:PEX29(display_short)|uniprotkb:Peroxin-29(gene name synonym)|uniprotkb:YDR479C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345534|imex:IM-14275-2873 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002407|refseq:NP_010033.1|dip:DIP-7527N|mint:Q07788|ensemblfungi:YDL248W(gene)|ensemblfungi:YDL248W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|interpro:IPR001142(Yeast membrane protein DUP) refseq:NP_010767.1|sgd:S000002887|mint:Q03370|dip:DIP-5175N|ensemblfungi:YDR479C(gene)|ensemblfungi:YDR479C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032581"(ER-dependent peroxisome organization)|interpro:IPR010482(Integral peroxisomal membrane peroxin) psi-mi:"MI:0469"(intact) - crc64:C2EB849C36FB69EB figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VxGUdE+UwAzvpTCt/MeNVhpZGKg559292 rogid:XirbTI20sgYx5DDsELcnS9RLxMw559292 intact-crc:ACE9CEA62005667A|rigid:JK23RCwxv78hhM9+QMul4PCsc4k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32588 uniprotkb:Q07807 intact:EBI-14231|ensemblfungi:YNL016W|uniprotkb:D6W1G2 intact:EBI-38012|uniprotkb:Q02601|uniprotkb:D6VXY9|ensemblfungi:YLL013C psi-mi:pub1_yeast(display_long)|uniprotkb:ARS consensus-binding protein ACBP-60(gene name synonym)|uniprotkb:Poly uridylate-binding protein(gene name synonym)|uniprotkb:PUB1(gene name)|psi-mi:PUB1(display_short)|uniprotkb:RNP1(gene name synonym)|uniprotkb:YNL016W(locus name)|uniprotkb:N2842(orf name) psi-mi:puf3_yeast(display_long)|uniprotkb:PUF3(gene name)|psi-mi:PUF3(display_short)|uniprotkb:YLL013C(locus name)|uniprotkb:L1325(orf name)|uniprotkb:Pumilio homology domain family member 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345545|imex:IM-14275-2874 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014382.1|sgd:S000004961|ensemblfungi:YNL016W(gene)|ensemblfungi:YNL016W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043488"(regulation of mRNA stability)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034509|interpro:IPR034639|interpro:IPR035979|rcsb pdb:2LA4|rcsb pdb:3MD1|rcsb pdb:3MD3|rcsb pdb:6Z29|mint:P32588|dip:DIP-5480N refseq:NP_013088.1|sgd:S000003936|dip:DIP-4449N|mint:Q07807|ensemblfungi:YLL013C(gene)|ensemblfungi:YLL013C_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0009060"(aerobic respiration)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010795"(regulation of ubiquinone biosynthetic process)|go:"GO:0032473"(cytoplasmic side of mitochondrial outer membrane)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051646"(mitochondrion localization)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:3K49|rcsb pdb:3K4E psi-mi:"MI:0469"(intact) crc64:3B81A7735505D3CA crc64:13F6D2D829CBCBF6 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8xFMuEva7leVYDKg3WOmvPtRTFk559292 rogid:9hEpfoVilyjxGQSuF9jKKFzz1n8559292 intact-crc:618B4D2033599250|rigid:k9Wol2TZ646HAW5IBLe2cLuO9R4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07824 uniprotkb:P19807 intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345556|imex:IM-14275-2875 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:835CFB732F76D47B|rigid:3UhLqaKA42lbAq/qtMM021NRhxE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:Q07824 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345567|imex:IM-14275-2876 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 intact-crc:9853C00F8C3DC7A1|rigid:s75EUcAXBr6mOm0QnYJSAEv9Odg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32568 uniprotkb:Q07824 intact:EBI-17590|uniprotkb:D6VRZ7|ensemblfungi:YDR011W intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W psi-mi:snq2_yeast(display_long)|uniprotkb:SNQ2(gene name)|psi-mi:SNQ2(display_short)|uniprotkb:YD8119.16(orf name)|uniprotkb:YDR011W(locus name) psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345578|imex:IM-14275-2877 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010294.1|sgd:S000002418|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR027417|ensemblfungi:YDR011W(gene)|ensemblfungi:YDR011W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|interpro:IPR029481|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR034001|interpro:IPR034003|mint:P32568|interpro:IPR043926 refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:tbnRu+/m7h+jq7jfp2T9ar7mfwA559292 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 intact-crc:5BBCA13C2F6A4182|rigid:7MrbikhMeDMTnB/5lmffJ6uKiFk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33202 uniprotkb:Q07824 intact:EBI-20010|uniprotkb:D6VXS6|ensemblfungi:YKL010C intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W psi-mi:ufd4_yeast(display_long)|uniprotkb:UFD4(gene name)|psi-mi:UFD4(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase UFD4(gene name synonym)|uniprotkb:YKL162(orf name)|uniprotkb:YKL010C(locus name) psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345589|imex:IM-14275-2878 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001493|ensemblfungi:YKL010C(gene)|ensemblfungi:YKL010C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1904855"(proteasome regulatory particle binding)|interpro:IPR000569(HECT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035983|reactome:R-SCE-983168|refseq:NP_012915.3|dip:DIP-4873N|mint:P33202 refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:A9B8B9D812C6216F - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:DGctb7Hmu2iOVSFY5RbPxFHrlag559292 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 intact-crc:77886971A5C59096|rigid:dLUtm6/jlIN/q3uzIdcwnFxFtKk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07824 uniprotkb:P33302 intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W intact:EBI-13038|uniprotkb:D6W2L0|ensemblfungi:YOR153W psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:pdr5_yeast(display_long)|uniprotkb:PDR5(gene name)|psi-mi:PDR5(display_short)|uniprotkb:LEM1(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 5(gene name synonym)|uniprotkb:Suppressor of toxicity of sporidesmin(gene name synonym)|uniprotkb:YOR153W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345601|imex:IM-14275-2879 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 sgd:S000005679|refseq:NP_014796.3|mint:P33302|dip:DIP-6776N|ensemblfungi:YOR153W(gene)|ensemblfungi:YOR153W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR029481|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 rogid:Sd6SJWf6B0rDZnLVaPHyvr4lhew559292 intact-crc:B9670871A5C12DEF|rigid:YhICvQEJMfh5Uir1OjGgNZOprN8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07824 uniprotkb:P33413 intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W intact:EBI-2060312|uniprotkb:D3DKP5|ensemblfungi:YHL016C psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:dur3_yeast(display_long)|uniprotkb:DUR3(gene name)|psi-mi:DUR3(display_short)|uniprotkb:YHL016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345612|imex:IM-14275-2880 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 interpro:IPR031155|refseq:NP_011847.1|sgd:S000001008|interpro:IPR001734(Na+/solute symporter)|interpro:IPR038377|mint:P33413|ensemblfungi:YHL016C(gene)|ensemblfungi:YHL016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0015204"(urea transmembrane transporter activity)|go:"GO:0015489"(putrescine transmembrane transporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015840"(urea transport)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 rogid:oTFsdtOngA3q5wCbhK/fpVlIsz0559292 intact-crc:6F8A2F751C1AFE59|rigid:+yY1OfeUTO3/iLfZ5hPeU2W0/jc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07824 uniprotkb:P35735 intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345623|imex:IM-14275-2881 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:487FEF289A7880E0|rigid:DhNPCT2bY4G+kktyd89Uy8y5VFE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:Q07824 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345634|imex:IM-14275-2882 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 intact-crc:4B91F982E429F657|rigid:VQOk9Dpgi8XA+l1AzVm9/CgiIbQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38234 uniprotkb:Q07824 intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345645|imex:IM-14275-2883 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 intact-crc:A9DF21112717639E|rigid:0T2LOy3nRgua4plqwFUqu6Ut8CM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07824 uniprotkb:P38695 intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345656|imex:IM-14275-2884 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N psi-mi:"MI:0469"(intact) - crc64:6906721BAC1A5F87 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 intact-crc:36A8A7C5B6ED31C8|rigid:3yTxw+SH2HYujGHFc6kd7EW7iCE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07824 uniprotkb:P48231 intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W intact:EBI-28779|uniprotkb:Q45TY9|uniprotkb:D6W192|ensemblfungi:YNL087W psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:tcb2_yeast(display_long)|uniprotkb:TCB2(gene name)|psi-mi:TCB2(display_short)|uniprotkb:N2250(orf name)|uniprotkb:YNL087W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345667|imex:IM-14275-2885 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_014312.1|sgd:S000005031|dip:DIP-2709N|mint:P48231|ensemblfungi:YNL087W(gene)|ensemblfungi:YNL087W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0071944"(cell periphery)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 rogid:1wgwUKMAl8d5ADdMQXtjWA0JtXU559292 intact-crc:82EF698B48889ACB|rigid:mdQueniWYywhyYXNRm6CGw24KgY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07824 uniprotkb:P50276 intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345678|imex:IM-14275-2886 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:C8205EA30911908B|rigid:MsMWBq11JhsgWbrw58VIrRMENHU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07824 uniprotkb:P53283 intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345689|imex:IM-14275-2887 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 intact-crc:BC0C6F167B57C40D|rigid:QkeivW8+FtIuFFeLzVbUOt30soI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53388 uniprotkb:Q07824 intact:EBI-5904|uniprotkb:D6W3A5|ensemblfungi:YPL265W intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W psi-mi:dip5_yeast(display_long)|uniprotkb:YPL265W(locus name)|uniprotkb:DIP5(gene name)|psi-mi:DIP5(display_short) psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345700|imex:IM-14275-2888 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015058.1|sgd:S000006186|dip:DIP-5540N|mint:P53388|ensemblfungi:YPL265W(gene)|ensemblfungi:YPL265W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:488A382656039D0B - figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TcjS7gtrFXNOhJrNDu8kVkxHs1w559292 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 intact-crc:79E2BCEE571513A2|rigid:49sDtkrFIpJBfk0mudxLeiFQCUg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07824 uniprotkb:Q02785 intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345711|imex:IM-14275-2889 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:05D5DDC0FE35D9B5|rigid:DbF7wxESJuxZ/jitMFGY88JYGUg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07824 uniprotkb:Q03640 intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345722|imex:IM-14275-2890 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) - crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:954853B781B0B398|rigid:umWYWx33vPY+PiWl7wfoMlItsWo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05812 uniprotkb:Q07824 intact:EBI-33150|uniprotkb:Q7LIF4|uniprotkb:D6VYL9|ensemblfungi:YLR219W intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W psi-mi:msc3_yeast(display_long)|uniprotkb:MSC3(gene name)|psi-mi:MSC3(display_short)|uniprotkb:YLR219W(locus name) psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345733|imex:IM-14275-2891 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004209|refseq:NP_013320.1|mint:Q05812|dip:DIP-6321N|ensemblfungi:YLR219W(gene)|ensemblfungi:YLR219W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007131"(reciprocal meiotic recombination) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:1962D638DB602B71 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:xS8zCG9eHY8V0vNstOwUuTcI3Ao559292 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 intact-crc:28B37EF8ED3563B3|rigid:6L72aewDUU/sfj6fH3frsBTsoVs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05942 uniprotkb:Q07824 intact:EBI-33602|uniprotkb:D6VYM1|ensemblfungi:YLR221C intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W psi-mi:rsa3_yeast(display_long)|uniprotkb:RSA3(gene name)|psi-mi:RSA3(display_short)|uniprotkb:YLR221C(locus name) psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345744|imex:IM-14275-2892 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004211|refseq:NP_013322.1|mint:Q05942|dip:DIP-4421N|ensemblfungi:YLR221C(gene)|ensemblfungi:YLR221C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR028217 refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Dz5+x9GLOTdeTL3BQlAv6niUiIs559292 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 intact-crc:84B91FF8FB794133|rigid:dCxh8AF5fxaChb/W162V57SwPp4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06170 uniprotkb:Q07824 intact:EBI-35994|uniprotkb:D6VYW8|ensemblfungi:YLR326W intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W psi-mi:yl326_yeast(display_long)|uniprotkb:YLR326W(locus name) psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345755|imex:IM-14275-2893 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013430.1|sgd:S000004318|mint:Q06170|dip:DIP-3995N|ensemblfungi:YLR326W(gene)|ensemblfungi:YLR326W_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR025187 refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:724CD7833AA9B416 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ufkoj1kRp4Y9JTsgbL+3k8hzJyo559292 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 intact-crc:566226528C681D14|rigid:pyDmziEcowaJ8gCxIeud7Z0q72g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06451 uniprotkb:Q07824 intact:EBI-34275|uniprotkb:D6W4F2|ensemblfungi:YPR156C intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W psi-mi:tpo3_yeast(display_long)|uniprotkb:TPO3(gene name)|psi-mi:TPO3(display_short)|uniprotkb:P9584.7(orf name)|uniprotkb:YPR156C(locus name) psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345766|imex:IM-14275-2894 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015482.1|sgd:S000006360|mint:Q06451|dip:DIP-3907N|ensemblfungi:YPR156C(gene)|ensemblfungi:YPR156C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:D260ED161F800502 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oVpx7Bjk/mK2Q7+/j05tX3gHw7k559292 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 intact-crc:1CF2C356387D3EF9|rigid:H03k+ilPkGA6hApCrD3yGqqv1AE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07824 uniprotkb:Q06689 intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W intact:EBI-38659|uniprotkb:D6VZ50|ensemblfungi:YLR413W psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:yl413_yeast(display_long)|uniprotkb:YLR413W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345777|imex:IM-14275-2895 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_013517.1|sgd:S000004405|mint:Q06689|dip:DIP-5075N|ensemblfungi:YLR413W(gene)|ensemblfungi:YLR413W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0071944"(cell periphery)|interpro:IPR009571(SUR7) psi-mi:"MI:0469"(intact) - crc64:92E23436DC857E95 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 rogid:AoTGKjLhw0NECrtuftZqLANonds559292 intact-crc:40C10173E01BD521|rigid:uJVyNUqnjp7bG4J39XWwacplNWI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:Q07824 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345788|imex:IM-14275-2896 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 intact-crc:7CD2EE37387440B7|rigid:dKI1m13vdLNWDTr7rfztw6kkgwA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07824 uniprotkb:Q07824 intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345799|imex:IM-14275-2897 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 intact-crc:852C5A19718A8563|rigid:YeNaJ1UakRmlWMMMaBQGI3o0fyM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3E756 uniprotkb:Q07824 intact:EBI-2044812|uniprotkb:D6VPX0|ensemblfungi:YBL029C-A intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W psi-mi:yb029_yeast(display_long)|uniprotkb:YBL029C-A(locus name) psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345810|imex:IM-14275-2898 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000007591|refseq:NP_076874.1|mint:Q3E756|ensemblfungi:YBL029C-A(gene)|ensemblfungi:YBL029C-A_mRNA(transcript)|go:"GO:0005886"(plasma membrane) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Y9LDkESr65DK5SLFNTw1dBKeqPc559292 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 intact-crc:139321DAE0FE983D|rigid:djiEnda7NehedNibtpN9raaFcWQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6Q5X2 uniprotkb:Q07824 intact:EBI-2043695|uniprotkb:D6VS22|ensemblfungi:YDR034W-B intact:EBI-38106|uniprotkb:D6VXX6|ensemblfungi:YLL028W psi-mi:yd34b_yeast(display_long)|uniprotkb:YDR034W-B(locus name) psi-mi:tpo1_yeast(display_long)|uniprotkb:TPO1(gene name)|psi-mi:TPO1(display_short)|uniprotkb:L0939(orf name)|uniprotkb:YLL028W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345821|imex:IM-14275-2899 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000007234|refseq:NP_010319.3|interpro:IPR028144|mint:Q6Q5X2|ensemblfungi:YDR034W-B(gene)|ensemblfungi:YDR034W-B_mRNA(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery) refseq:NP_013072.1|sgd:S000003951|mint:Q07824|dip:DIP-1706N|ensemblfungi:YLL028W(gene)|ensemblfungi:YLL028W_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015847"(putrescine transport)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902047"(polyamine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Q0HaYjXrSQxQGjBDwholuxLeSRo559292 rogid:93NE8CFoAM5WgAz5LOivJuDiiXc559292 intact-crc:B9BE77163240E7B0|rigid:GdMwDpMGXR2SAwE/cPcvoYk/HWQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06144 uniprotkb:Q07830 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W intact:EBI-32339|uniprotkb:D6VXX4|ensemblfungi:YLL031C psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:gpi13_yeast(display_long)|uniprotkb:Glycosylphosphatidylinositol-anchor biosynthesis protein 13(gene name synonym)|uniprotkb:GPI13(gene name)|psi-mi:GPI13(display_short)|uniprotkb:MPC1(gene name synonym)|uniprotkb:YLL031C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345832|imex:IM-14275-2900 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 refseq:NP_013069.1|sgd:S000003954|dip:DIP-5569N|mint:Q07830|ensemblfungi:YLL031C(gene)|ensemblfungi:YLL031C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016772"(transferase activity, transferring phosphorus-containing groups)|go:"GO:0051377"(mannose-ethanolamine phosphotransferase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR002591(Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR037675|interpro:IPR039524 psi-mi:"MI:0469"(intact) crc64:2F474503CAB7C195 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 rogid:yC4J6htMipU4zN5zRbQVUPiizAU559292 intact-crc:3C7AB3D3C5BD7BB9|rigid:htdyzx0RGMwlEitcWu2gRNu+CFs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07844 uniprotkb:Q07844 intact:EBI-27142|uniprotkb:D6VXX1|ensemblfungi:YLL034C intact:EBI-27142|uniprotkb:D6VXX1|ensemblfungi:YLL034C psi-mi:rix7_yeast(display_long)|uniprotkb:RIX7(gene name)|psi-mi:RIX7(display_short)|uniprotkb:YLL034C(locus name) psi-mi:rix7_yeast(display_long)|uniprotkb:RIX7(gene name)|psi-mi:RIX7(display_short)|uniprotkb:YLL034C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345843|imex:IM-14275-2901 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013066.1|sgd:S000003957|mint:Q07844|dip:DIP-6385N|ensemblfungi:YLL034C(gene)|ensemblfungi:YLL034C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990275"(preribosome binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569 refseq:NP_013066.1|sgd:S000003957|mint:Q07844|dip:DIP-6385N|ensemblfungi:YLL034C(gene)|ensemblfungi:YLL034C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990275"(preribosome binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569 psi-mi:"MI:0469"(intact) crc64:133528B9D0987103 crc64:133528B9D0987103 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:CEDaCFQQsHNDc1vhyXrgiMUNzO4559292 rogid:CEDaCFQQsHNDc1vhyXrgiMUNzO4559292 intact-crc:C1ABCC23BED9A9F7|rigid:iib0S3/tU1OF8v+M7C+4U0R/FPE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54858 uniprotkb:Q07950 intact:EBI-6042|uniprotkb:D6VS54|ensemblfungi:YDR068W intact:EBI-35781|uniprotkb:D6VY22|ensemblfungi:YLR020C psi-mi:dos2_yeast(display_long)|uniprotkb:D4267(orf name)|uniprotkb:YD8554.01(orf name)|uniprotkb:YD9609.22(orf name)|uniprotkb:DOS2(gene name)|psi-mi:DOS2(display_short)|uniprotkb:YDR068W(locus name) psi-mi:yeh2_yeast(display_long)|uniprotkb:YLR020C(locus name)|uniprotkb:YEH2(gene name)|psi-mi:YEH2(display_short)|uniprotkb:Steryl ester hydrolase 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345854|imex:IM-14275-2902 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002475|refseq:NP_010353.3|dip:DIP-4785N|mint:P54858|ensemblfungi:YDR068W(gene)|ensemblfungi:YDR068W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR005607(BSD)|interpro:IPR035925 refseq:NP_013120.1|sgd:S000004010|interpro:IPR006693(AB-hydrolase associated lipase region)|interpro:IPR029058|mint:Q07950|ensemblfungi:YLR020C(gene)|ensemblfungi:YLR020C_mRNA(transcript)|go:"GO:0000032"(cell wall mannoprotein biosynthetic process)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0071944"(cell periphery)|reactome:R-SCE-192456|reactome:R-SCE-6809371 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:/4fnAAPmC12DMUbUB8MVS9yjjeg559292 rogid:DvjMCncuvov8Q7FxdbiG1g0UPC0559292 intact-crc:329411190B20E2D1|rigid:qpz52ogq1r+sKhMuepA22lyd3YQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07953 uniprotkb:Q07953 intact:EBI-27124|uniprotkb:D6VY24|ensemblfungi:YLR022C intact:EBI-27124|uniprotkb:D6VY24|ensemblfungi:YLR022C psi-mi:sdo1_yeast(display_long)|uniprotkb:YLR022C(locus name)|uniprotkb:SDO1(gene name)|psi-mi:SDO1(display_short) psi-mi:sdo1_yeast(display_long)|uniprotkb:YLR022C(locus name)|uniprotkb:SDO1(gene name)|psi-mi:SDO1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345865|imex:IM-14275-2903 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013122.1|sgd:S000004012|interpro:IPR018978|interpro:IPR018023|interpro:IPR019783|interpro:IPR002140(Shwachman-Bodian-Diamond syndrome related)|mint:Q07953|interpro:IPR036786|interpro:IPR037188|interpro:IPR039100|ensemblfungi:YLR022C(gene)|ensemblfungi:YLR022C_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0042256"(mature ribosome assembly) refseq:NP_013122.1|sgd:S000004012|interpro:IPR018978|interpro:IPR018023|interpro:IPR019783|interpro:IPR002140(Shwachman-Bodian-Diamond syndrome related)|mint:Q07953|interpro:IPR036786|interpro:IPR037188|interpro:IPR039100|ensemblfungi:YLR022C(gene)|ensemblfungi:YLR022C_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0042256"(mature ribosome assembly) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hneEs5QCkMZ63vvBEHQArADKpOw559292 rogid:hneEs5QCkMZ63vvBEHQArADKpOw559292 intact-crc:D7047A7C5CC2EEDC|rigid:qCKY2J6DhLBH3Y8mOpjfStgkvQE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15496 uniprotkb:Q07979 intact:EBI-8902|ensemblfungi:YPL117C|uniprotkb:D6W3Q1 intact:EBI-36549|uniprotkb:D6VY35|ensemblfungi:YLR033W psi-mi:idi1_yeast(display_long)|uniprotkb:Isopentenyl pyrophosphate isomerase(gene name synonym)|uniprotkb:IDI1(gene name)|psi-mi:IDI1(display_short)|uniprotkb:BOT2(gene name synonym)|uniprotkb:YPL117C(locus name)|uniprotkb:LPH10C(orf name) psi-mi:rsc58_yeast(display_long)|uniprotkb:Remodel the structure of chromatin complex subunit 58(gene name synonym)|uniprotkb:RSC58(gene name)|psi-mi:RSC58(display_short)|uniprotkb:YLR033W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345876|imex:IM-14275-2904 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL117C(gene)|ensemblfungi:YPL117C_mRNA(transcript)|go:"GO:0004452"(isopentenyl-diphosphate delta-isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009240"(isopentenyl diphosphate biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0045337"(farnesyl diphosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050992"(dimethylallyl diphosphate biosynthetic process)|reactome:R-SCE-191273|refseq:NP_015208.1|sgd:S000006038|interpro:IPR011876(Isopentenyl-diphosphate delta-isomerase, type 1)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|mint:P15496 refseq:NP_013133.1|sgd:S000004023|mint:Q07979|dip:DIP-6656N|ensemblfungi:YLR033W(gene)|ensemblfungi:YLR033W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016586"(RSC-type complex)|go:"GO:0043044"|interpro:IPR001487(Bromodomain)|interpro:IPR036427|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6TDA|rcsb pdb:6V8O|rcsb pdb:6V92 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:KQ9qSb2grQ4DQip7atYPeCwp5QM559292 rogid:0Te8g3xp6E2xvFZFENXsO0BroLw559292 intact-crc:851ACF3A9B7D0524|rigid:Svygx1vG0+uTj5lcUcXnhap1Agg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07979 uniprotkb:P40350 intact:EBI-36549|uniprotkb:D6VY35|ensemblfungi:YLR033W intact:EBI-2470|uniprotkb:D6W3E3|ensemblfungi:YPL227C psi-mi:rsc58_yeast(display_long)|uniprotkb:Remodel the structure of chromatin complex subunit 58(gene name synonym)|uniprotkb:RSC58(gene name)|psi-mi:RSC58(display_short)|uniprotkb:YLR033W(locus name) psi-mi:alg5_yeast(display_long)|uniprotkb:ALG5(gene name)|psi-mi:ALG5(display_short)|uniprotkb:YPL227C(locus name)|uniprotkb:P1437(orf name)|uniprotkb:Asparagine-linked glycosylation protein 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345887|imex:IM-14275-2905 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013133.1|sgd:S000004023|mint:Q07979|dip:DIP-6656N|ensemblfungi:YLR033W(gene)|ensemblfungi:YLR033W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016586"(RSC-type complex)|go:"GO:0043044"|interpro:IPR001487(Bromodomain)|interpro:IPR036427|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6TDA|rcsb pdb:6V8O|rcsb pdb:6V92 refseq:NP_015097.1|sgd:S000006148|dip:DIP-5651N|mint:P40350|ensemblfungi:YPL227C(gene)|ensemblfungi:YPL227C_mRNA(transcript)|go:"GO:0004581"(dolichyl-phosphate beta-glucosyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR035518|reactome:R-SCE-480985 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0Te8g3xp6E2xvFZFENXsO0BroLw559292 rogid:aKi97cbwqo7kNWhtRyzG3UOLH4U559292 intact-crc:8651A8E6C7D95A39|rigid:fEaEZAj32qzGRpPY7gYzhWjCbGA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43593 uniprotkb:Q07979 intact:EBI-19852|uniprotkb:D6VTP0|ensemblfungi:YFR010W intact:EBI-36549|uniprotkb:D6VY35|ensemblfungi:YLR033W psi-mi:ubp6_yeast(display_long)|uniprotkb:UBP6(gene name)|psi-mi:UBP6(display_short)|uniprotkb:Ubiquitin-specific-processing protease 6(gene name synonym)|uniprotkb:Deubiquitinating enzyme 6(gene name synonym)|uniprotkb:Ubiquitin thioesterase 6(gene name synonym)|uniprotkb:YFR010W(locus name) psi-mi:rsc58_yeast(display_long)|uniprotkb:Remodel the structure of chromatin complex subunit 58(gene name synonym)|uniprotkb:RSC58(gene name)|psi-mi:RSC58(display_short)|uniprotkb:YLR033W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345898|imex:IM-14275-2906 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116665.1|sgd:S000001906|ensemblfungi:YFR010W(gene)|ensemblfungi:YFR010W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR000626(Ubiquitin)|interpro:IPR028889|interpro:IPR029071|interpro:IPR038765|interpro:IPR044635|rcsb pdb:1VJV|rcsb pdb:5A5B|rcsb pdb:5MPC|reactome:R-SCE-5689880|dip:DIP-6731N|mint:P43593 refseq:NP_013133.1|sgd:S000004023|mint:Q07979|dip:DIP-6656N|ensemblfungi:YLR033W(gene)|ensemblfungi:YLR033W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016586"(RSC-type complex)|go:"GO:0043044"|interpro:IPR001487(Bromodomain)|interpro:IPR036427|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6TDA|rcsb pdb:6V8O|rcsb pdb:6V92 psi-mi:"MI:0469"(intact) crc64:DAE54D1F8AC9960C - figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:M4HqdW/7V42HuFuSm4y6z4Oz6tg559292 rogid:0Te8g3xp6E2xvFZFENXsO0BroLw559292 intact-crc:33BB1D983EC65A8E|rigid:WRqxrPEeCl+EMuznQ5JwMEyrIFc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07979 uniprotkb:Q03010 intact:EBI-36549|uniprotkb:D6VY35|ensemblfungi:YLR033W intact:EBI-20070|uniprotkb:P87330|uniprotkb:D6W3M9|ensemblfungi:YPL139C psi-mi:rsc58_yeast(display_long)|uniprotkb:Remodel the structure of chromatin complex subunit 58(gene name synonym)|uniprotkb:RSC58(gene name)|psi-mi:RSC58(display_short)|uniprotkb:YLR033W(locus name) psi-mi:ume1_yeast(display_long)|uniprotkb:UME1(gene name)|psi-mi:UME1(display_short)|uniprotkb:WTM3(gene name synonym)|uniprotkb:YPL139C(locus name)|uniprotkb:LPI7C(orf name)|uniprotkb:WD repeat-containing transcriptional modulator 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345909|imex:IM-14275-2907 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013133.1|sgd:S000004023|mint:Q07979|dip:DIP-6656N|ensemblfungi:YLR033W(gene)|ensemblfungi:YLR033W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016586"(RSC-type complex)|go:"GO:0043044"|interpro:IPR001487(Bromodomain)|interpro:IPR036427|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6TDA|rcsb pdb:6V8O|rcsb pdb:6V92 refseq:NP_015186.1|sgd:S000006060|ensemblfungi:YPL139C(gene)|ensemblfungi:YPL139C_mRNA(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070210"(Rpd3L-Expanded complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR036322|reactome:R-SCE-3214815|reactome:R-SCE-3214847|reactome:R-SCE-3214858|dip:DIP-5290N|mint:Q03010 psi-mi:"MI:0469"(intact) - crc64:AA6F60448B7BCBA9 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0Te8g3xp6E2xvFZFENXsO0BroLw559292 rogid:radf8gBaPrKRK281JuKAYZprO34559292 intact-crc:262ADB76BFF07607|rigid:DYgFXZw2l7wMv22zlW6v/NsOCzY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53032 uniprotkb:Q07980 intact:EBI-18586|ensemblfungi:YGL162W|uniprotkb:D6VTY9 intact:EBI-33369|uniprotkb:D6VY37|ensemblfungi:YLR035C psi-mi:sut1_yeast(display_long)|uniprotkb:SUT1(gene name)|psi-mi:SUT1(display_short)|uniprotkb:G1828(orf name)|uniprotkb:YGL162W(locus name) psi-mi:mlh2_yeast(display_long)|uniprotkb:MutL protein homolog 2(gene name synonym)|uniprotkb:YLR035C(locus name)|uniprotkb:MLH2(gene name)|psi-mi:MLH2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345920|imex:IM-14275-2908 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL162W(gene)|ensemblfungi:YGL162W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR036864|refseq:NP_011353.1|sgd:S000003130|dip:DIP-5748N|mint:P53032 refseq:NP_013135.1|sgd:S000004025|mint:Q07980|dip:DIP-2413N|ensemblfungi:YLR035C(gene)|ensemblfungi:YLR035C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032390"(MutLbeta complex)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR036890|interpro:IPR038973 psi-mi:"MI:0469"(intact) - crc64:DA5DA6AC86603A81 figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0dfbc9nXW+fJd27Z83OQQBzx+gs559292 rogid:K4rhQBLgfkvQJE83VJLDeOZHk+U559292 intact-crc:E388A30C07B8763F|rigid:/ZYzHmVlh83Vet/cy4CliqRjbyA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08176 uniprotkb:P38985 intact:EBI-31062|uniprotkb:D6W239|ensemblfungi:YOL026C intact:EBI-17977|uniprotkb:D6VRQ6|ensemblfungi:YDL092W psi-mi:mim1_yeast(display_long)|uniprotkb:Mitochondrial 13 kDa outer membrane protein(gene name synonym)|uniprotkb:MIM1(gene name)|psi-mi:MIM1(display_short)|uniprotkb:TOM13(gene name synonym)|uniprotkb:YOL026C(locus name) psi-mi:srp14_yeast(display_long)|uniprotkb:SRP14(gene name)|psi-mi:SRP14(display_short)|uniprotkb:YDL092W(locus name)|uniprotkb:D2404(orf name)|uniprotkb:Signal recognition particle 14 kDa protein homolog(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345931|imex:IM-14275-2909 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014616.1|sgd:S000005386|interpro:IPR013262(Outer membrane protein, MIM1/TOM13, mitochondrial)|mint:Q08176|ensemblfungi:YOL026C(gene)|ensemblfungi:YOL026C_mRNA(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0070096"(mitochondrial outer membrane translocase complex assembly) refseq:NP_010191.1|sgd:S000002250|ensemblfungi:YDL092W(gene)|ensemblfungi:YDL092W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR003210(Signal recognition particle, SRP14 subunit)|interpro:IPR009018(Signal recognition particle, SRP9/SRP14 subunit)|reactome:R-SCE-1799339|reactome:R-SCE-6798695|dip:DIP-4864N|mint:P38985 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WQVjFbpO1VhMiQOyfj4h3M583yY559292 rogid:I9myDFdKPRnrKsHBhWBxI/Em7EQ559292 intact-crc:6B705DBCF24FC1FE|rigid:IOPeuNF6HtylBlrx8p9YQUTFZLE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TGU5 uniprotkb:Q08235 intact:EBI-2042814|uniprotkb:D6VQU1|ensemblfungi:YBR296C-A intact:EBI-3775|uniprotkb:D6W1Z1|ensemblfungi:YOL077C psi-mi:yb296_yeast(display_long)|uniprotkb:YBR296C-A(locus name) psi-mi:brx1_yeast(display_long)|uniprotkb:YOL077C(locus name)|uniprotkb:BRX1(gene name)|psi-mi:BRX1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345942|imex:IM-14275-2910 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000028605|refseq:NP_878055.3|mint:Q8TGU5|ensemblfungi:YBR296C-A(gene)|ensemblfungi:YBR296C-A_mRNA(transcript)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity) refseq:NP_014565.2|sgd:S000005437|dip:DIP-6317N|mint:Q08235|ensemblfungi:YOL077C(gene)|ensemblfungi:YOL077C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000464"("endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000465"("exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR007109(Brix)|interpro:IPR026532|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5 psi-mi:"MI:0469"(intact) - crc64:31466853EF0E7301 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:DZubWD7lnwtea4Ne/bK1ITPFaJk559292 rogid:mPR6HWKwM6RNCRE/vezsYlCmEGY559292 intact-crc:E638295DF126051A|rigid:W556HBOKfkmfqIoOlzQ8dqvrG+w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08280 uniprotkb:P09620 intact:EBI-35858|uniprotkb:Q6B229|uniprotkb:D6W1T2|ensemblfungi:YOL137W intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:bsc6_yeast(display_long)|uniprotkb:YOL137W(locus name)|uniprotkb:BSC6(gene name)|psi-mi:BSC6(display_short) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345953|imex:IM-14275-2911 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014504.1|sgd:S000005497|mint:Q08280|dip:DIP-4683N|ensemblfungi:YOL137W(gene)|ensemblfungi:YOL137W_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WVYZke8YJvNcS4D9bUnthAFdq3A559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:F573A38D37FE1ED9|rigid:TUDQePGXGteL8BlY8LBlMkiafnE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:Q08280 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-35858|uniprotkb:Q6B229|uniprotkb:D6W1T2|ensemblfungi:YOL137W psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:bsc6_yeast(display_long)|uniprotkb:YOL137W(locus name)|uniprotkb:BSC6(gene name)|psi-mi:BSC6(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345964|imex:IM-14275-2912 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 refseq:NP_014504.1|sgd:S000005497|mint:Q08280|dip:DIP-4683N|ensemblfungi:YOL137W(gene)|ensemblfungi:YOL137W_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:WVYZke8YJvNcS4D9bUnthAFdq3A559292 intact-crc:A7BF6071CFB87A56|rigid:CxriFZHqa9vqDoUJIEm2AYPtPM0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32793 uniprotkb:Q08412 intact:EBI-24460|uniprotkb:D3DKW1|ensemblfungi:YHR016C intact:EBI-37580|uniprotkb:D6W2A8|ensemblfungi:YOR042W psi-mi:ysc84_yeast(display_long)|uniprotkb:YSC84(gene name)|psi-mi:YSC84(display_short)|uniprotkb:LSB4(gene name synonym)|uniprotkb:LAS seventeen-binding protein 4(gene name synonym)|uniprotkb:YHR016C(locus name) psi-mi:cue5_yeast(display_long)|uniprotkb:YOR042W(locus name)|uniprotkb:CUE5(gene name)|psi-mi:CUE5(display_short)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345975|imex:IM-14275-2913 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011880.1|sgd:S000001058|dip:DIP-2026N|mint:P32793|ensemblfungi:YHR016C(gene)|ensemblfungi:YHR016C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:2A08 refseq:NP_014685.1|sgd:S000005568|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|mint:Q08412|interpro:IPR041807|ensemblfungi:YOR042W(gene)|ensemblfungi:YOR042W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043130"(ubiquitin binding)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) crc64:DE42E8ECF5B83C92 crc64:0D455F9AD637AC8D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hirm/OlqdPxvJNPbha68BSFIvmQ559292 rogid:bUu2kNMFibdM8RUj460pMdBr2UA559292 intact-crc:EC322D921D6A5311|rigid:3zJOTMgo7t110FbOGGiK/nVoMSs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08412 uniprotkb:P43603 intact:EBI-37580|uniprotkb:D6W2A8|ensemblfungi:YOR042W intact:EBI-22980|uniprotkb:D6VTQ4|ensemblfungi:YFR024C-A psi-mi:cue5_yeast(display_long)|uniprotkb:YOR042W(locus name)|uniprotkb:CUE5(gene name)|psi-mi:CUE5(display_short)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 5(gene name synonym) psi-mi:lsb3_yeast(display_long)|uniprotkb:LSB3(gene name)|psi-mi:LSB3(display_short)|uniprotkb:YFR024C(orf name)|uniprotkb:YFR024C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345986|imex:IM-14275-2914 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014685.1|sgd:S000005568|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|mint:Q08412|interpro:IPR041807|ensemblfungi:YOR042W(gene)|ensemblfungi:YOR042W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043130"(ubiquitin binding)|reactome:R-SCE-6798695 sgd:S000002968|refseq:NP_219497.4|dip:DIP-6259N|mint:P43603|ensemblfungi:YFR024C-A(gene)|ensemblfungi:YFR024C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:1OOT|rcsb pdb:1SSH psi-mi:"MI:0469"(intact) crc64:0D455F9AD637AC8D crc64:F486C787B5771AAC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:bUu2kNMFibdM8RUj460pMdBr2UA559292 rogid:zKMZQRpG4d/at/NecQDyEi/kVKg559292 intact-crc:357B5B7F1B385F90|rigid:b9iLM7Dx3e0+LPVASI8JtWHgHCo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08412 uniprotkb:Q08412 intact:EBI-37580|uniprotkb:D6W2A8|ensemblfungi:YOR042W intact:EBI-37580|uniprotkb:D6W2A8|ensemblfungi:YOR042W psi-mi:cue5_yeast(display_long)|uniprotkb:YOR042W(locus name)|uniprotkb:CUE5(gene name)|psi-mi:CUE5(display_short)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 5(gene name synonym) psi-mi:cue5_yeast(display_long)|uniprotkb:YOR042W(locus name)|uniprotkb:CUE5(gene name)|psi-mi:CUE5(display_short)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6345997|imex:IM-14275-2915 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014685.1|sgd:S000005568|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|mint:Q08412|interpro:IPR041807|ensemblfungi:YOR042W(gene)|ensemblfungi:YOR042W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043130"(ubiquitin binding)|reactome:R-SCE-6798695 refseq:NP_014685.1|sgd:S000005568|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|mint:Q08412|interpro:IPR041807|ensemblfungi:YOR042W(gene)|ensemblfungi:YOR042W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043130"(ubiquitin binding)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) crc64:0D455F9AD637AC8D crc64:0D455F9AD637AC8D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:bUu2kNMFibdM8RUj460pMdBr2UA559292 rogid:bUu2kNMFibdM8RUj460pMdBr2UA559292 intact-crc:06396FABD7F9D809|rigid:9n+exKNkVakhFqcXHdM54Jh9dPc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10614 uniprotkb:Q08438 intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346008|imex:IM-14275-2916 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551 psi-mi:"MI:0469"(intact) - crc64:A97623473CB6F605 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292 intact-crc:6A5652FAE0E844A5|rigid:9T8UJSSYxgNNnNYbwzqFLS6yYBM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:Q08438 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346019|imex:IM-14275-2917 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551 psi-mi:"MI:0469"(intact) crc64:8B7F009521F72C15 crc64:A97623473CB6F605 figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292 intact-crc:F2E3434FAD8CECF4|rigid:3N/QhSuFkXchCOLbvVZERn+2OF8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08438 uniprotkb:P38264 intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C intact:EBI-13350|ensemblfungi:YBR106W|uniprotkb:D6VQA5 psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name) psi-mi:pho88_yeast(display_long)|uniprotkb:PHO88(gene name)|psi-mi:PHO88(display_short)|uniprotkb:Phosphate metabolism protein PHO88(gene name synonym)|uniprotkb:Inorganic phosphate transport protein PHO88(gene name synonym)|uniprotkb:SND3(gene name synonym)|uniprotkb:YBR0835(orf name)|uniprotkb:YBR106W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346030|imex:IM-14275-2918 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551 refseq:NP_009664.1|sgd:S000000310|ensemblfungi:YBR106W(gene)|ensemblfungi:YBR106W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0051604"(protein maturation)|interpro:IPR012098(Inorganic phosphate transport PHO88)|mint:P38264|dip:DIP-4888N psi-mi:"MI:0469"(intact) crc64:A97623473CB6F605 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292 rogid:K/gnKBetGPWsORLQZLcNxs4+4qE559292 intact-crc:7D40502C3DC8F868|rigid:lPV6WkFHWZrT2UHmAxdDmsz/UKQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38353 uniprotkb:Q08438 intact:EBI-18175|uniprotkb:D6VQS8|ensemblfungi:YBR283C intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C psi-mi:ssh1_yeast(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:Ssh1 complex subunit alpha(gene name synonym)|uniprotkb:Ssh1 complex subunit SSH1(gene name synonym)|uniprotkb:YBR2020(orf name)|uniprotkb:YBR283C(locus name) psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346041|imex:IM-14275-2919 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009842.1|sgd:S000000487|ensemblfungi:YBR283C(gene)|ensemblfungi:YBR283C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:2WW9|rcsb pdb:2WWA|dip:DIP-4962N|mint:P38353 refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551 psi-mi:"MI:0469"(intact) crc64:48267EEA3E0191BD crc64:A97623473CB6F605 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:76wvZIdv7W5BQn6wI+sHOGQAyuc559292 rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292 intact-crc:050C313302670677|rigid:YVVcYRdo+Ob7u31w3M95pofDIkE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08438 uniprotkb:P38694 intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C intact:EBI-24511|uniprotkb:D3DKY6|ensemblfungi:YHR039C psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name) psi-mi:msc7_yeast(display_long)|uniprotkb:MSC7(gene name)|psi-mi:MSC7(display_short)|uniprotkb:Meiotic sister-chromatid recombination protein 7(gene name synonym)|uniprotkb:YHR039C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346052|imex:IM-14275-2920 author score:99.36 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551 refseq:NP_011904.1|sgd:S000001081|dip:DIP-1878N|mint:P38694|ensemblfungi:YHR039C(gene)|ensemblfungi:YHR039C_mRNA(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007131"(reciprocal meiotic recombination)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510 psi-mi:"MI:0469"(intact) crc64:A97623473CB6F605 - figure legend:tables S3 and S4|author-confidence:99.36|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292 rogid:p2xtb6/xYI/jfPNtO6JRZs+5t6I559292 intact-crc:81D776FC0703AD85|rigid:Yr9IXhNK2e+NZWQqp4H3oCxiayU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47155 uniprotkb:Q08438 intact:EBI-2051644|uniprotkb:D6VWT7|ensemblfungi:YJR118C intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C psi-mi:ilm1_yeast(display_long)|uniprotkb:Increased loss of mitochondrial DNA protein 1(gene name synonym)|uniprotkb:J2033(orf name)|uniprotkb:ILM1(gene name)|psi-mi:ILM1(display_short)|uniprotkb:YJR118C(locus name) psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346063|imex:IM-14275-2921 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003879|interpro:IPR018815|refseq:NP_012652.3|mint:P47155|ensemblfungi:YJR118C(gene)|ensemblfungi:YJR118C_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane) refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551 psi-mi:"MI:0469"(intact) - crc64:A97623473CB6F605 figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BrQhbXGvUjNG6Bt5c0J7T8qzMeI559292 rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292 intact-crc:EEE0CFEBAA7B17CE|rigid:qRLnn/rvO/HuIJwsvQarYcKHXY4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08438 uniprotkb:P54837 intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name) psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346074|imex:IM-14275-2922 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551 refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:A97623473CB6F605 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 intact-crc:6F805ACEAA26696D|rigid:/quEgVTjlD5RQBrmwW0v3wH4Xcc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:Q08438 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346085|imex:IM-14275-2923 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551 psi-mi:"MI:0469"(intact) - crc64:A97623473CB6F605 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292 intact-crc:CC07A63DDF39C74D|rigid:BQ6iDFrAwgdeW63dd+J/9KVBeCg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06144 uniprotkb:Q08438 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346096|imex:IM-14275-2924 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551 psi-mi:"MI:0469"(intact) crc64:2F474503CAB7C195 crc64:A97623473CB6F605 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292 intact-crc:55BB55AD78DEF2BB|rigid:hroLXwOX3XmwWSt9xfL1ipfUzBM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:Q08491 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1389|ensemblfungi:YOR076C|uniprotkb:O00032|uniprotkb:D6W2D9 psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:ski7_yeast(display_long)|uniprotkb:SKI7(gene name)|psi-mi:SKI7(display_short)|uniprotkb:YOR29-27(orf name)|uniprotkb:YOR076C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346107|imex:IM-14275-2925 author score:99.36 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 ensemblfungi:YOR076C(gene)|ensemblfungi:YOR076C_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR027417|rcsb pdb:4ZKD|rcsb pdb:4ZKE|rcsb pdb:5G06|rcsb pdb:5JEA|refseq:NP_014719.1|sgd:S000005602|dip:DIP-995N|mint:Q08491 psi-mi:"MI:0469"(intact) crc64:52D3416EA183583B crc64:D93B956D02050BFA figure legend:tables S3 and S4|author-confidence:99.36|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:lSRCPXKyO8g/c9UBMPr/zgCwS84559292 intact-crc:99089C5FA242162F|rigid:lWRwSxJ90TXM3rx60zCbtZ2J/6g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02772 uniprotkb:Q08581 intact:EBI-14134|ensemblfungi:YJR034W|uniprotkb:D6VWK7 intact:EBI-38556|uniprotkb:D6W2Q4|ensemblfungi:YOR195W psi-mi:pt191_yeast(display_long)|uniprotkb:PET191(gene name)|psi-mi:PET191(display_short)|uniprotkb:J1604(orf name)|uniprotkb:YJR034W(locus name) psi-mi:slk19_yeast(display_long)|uniprotkb:Synthetic lethal KAR3 protein 19(gene name synonym)|uniprotkb:SLK19(gene name)|psi-mi:SLK19(display_short)|uniprotkb:YOR195W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346118|imex:IM-14275-2926 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YJR034W(gene)|ensemblfungi:YJR034W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR018793|refseq:NP_012568.1|sgd:S000003795|mint:Q02772|dip:DIP-1619N sgd:S000005721|refseq:NP_014838.3|mint:Q08581|dip:DIP-2595N|ensemblfungi:YOR195W(gene)|ensemblfungi:YOR195W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007097"(nuclear migration)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0098653"(centromere clustering)|interpro:IPR024312 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Y2xXA5HsKzl3I4/DuFs5+mLaJUo559292 rogid:3ufBU9ElgshvxT7WluCx2lQX2Rs559292 intact-crc:67BDA578A8068368|rigid:tS5Gg0KBLuygNvrgGDCY4lpipsg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08581 uniprotkb:Q08581 intact:EBI-38556|uniprotkb:D6W2Q4|ensemblfungi:YOR195W intact:EBI-38556|uniprotkb:D6W2Q4|ensemblfungi:YOR195W psi-mi:slk19_yeast(display_long)|uniprotkb:Synthetic lethal KAR3 protein 19(gene name synonym)|uniprotkb:SLK19(gene name)|psi-mi:SLK19(display_short)|uniprotkb:YOR195W(locus name) psi-mi:slk19_yeast(display_long)|uniprotkb:Synthetic lethal KAR3 protein 19(gene name synonym)|uniprotkb:SLK19(gene name)|psi-mi:SLK19(display_short)|uniprotkb:YOR195W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346129|imex:IM-14275-2927 author score:98.67 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005721|refseq:NP_014838.3|mint:Q08581|dip:DIP-2595N|ensemblfungi:YOR195W(gene)|ensemblfungi:YOR195W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007097"(nuclear migration)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0098653"(centromere clustering)|interpro:IPR024312 sgd:S000005721|refseq:NP_014838.3|mint:Q08581|dip:DIP-2595N|ensemblfungi:YOR195W(gene)|ensemblfungi:YOR195W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007097"(nuclear migration)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0098653"(centromere clustering)|interpro:IPR024312 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.67|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3ufBU9ElgshvxT7WluCx2lQX2Rs559292 rogid:3ufBU9ElgshvxT7WluCx2lQX2Rs559292 intact-crc:4B83288742A1E949|rigid:9hhufBGfc3xZfW4eFoozcvZ4q+k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43588 uniprotkb:Q08723 intact:EBI-11219|uniprotkb:Q8J0T5|uniprotkb:D6VTN4|ensemblfungi:YFR004W intact:EBI-36176|uniprotkb:Q6Q5I7|uniprotkb:D6W2W2|ensemblfungi:YOR261C psi-mi:rpn11_yeast(display_long)|uniprotkb:YFR004W(locus name)|uniprotkb:RPN11(gene name)|psi-mi:RPN11(display_short)|uniprotkb:MPR1(gene name synonym)|uniprotkb:Protein MPR1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN11(gene name synonym) psi-mi:rpn8_yeast(display_long)|uniprotkb:RPN8(gene name)|psi-mi:RPN8(display_short)|uniprotkb:O5360(orf name)|uniprotkb:YOR261C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346140|imex:IM-14275-2928 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YFR004W(gene)|ensemblfungi:YFR004W_mRNA(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016559"(peroxisome fission)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070628"(proteasome binding)|go:"GO:1902906"(proteasome storage granule assembly)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4O8X|rcsb pdb:4O8Y|rcsb pdb:4OCL|rcsb pdb:4OCM|go:"GO:0070122"(isopeptidase activity)|rcsb pdb:4OCN|rcsb pdb:4OWP|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5U4P|rcsb pdb:5W83|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-5689901|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|refseq:NP_116659.1|sgd:S000001900|mint:P43588|dip:DIP-1573N sgd:S000005787|refseq:NP_014904.3|mint:Q08723|dip:DIP-1574N|ensemblfungi:YOR261C(gene)|ensemblfungi:YOR261C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4O8X|rcsb pdb:4O8Y|rcsb pdb:4OCL|rcsb pdb:4OCM|rcsb pdb:4OCN|rcsb pdb:4OWP|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5U4P|rcsb pdb:5W83|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168 psi-mi:"MI:0469"(intact) crc64:9DDE8BD74890894D crc64:6EE6009545A3D0EF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:f3lAMY9siMcO2dAOfKvVrvKzfNM559292 rogid:kvJ/LyyQGKi5JTh4Fek1kh70jOU559292 intact-crc:4BE8D8A7406812A4|rigid:cfJWuDPe61upsHj4QTvPviQza/E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08723 uniprotkb:Q04062 intact:EBI-36176|uniprotkb:Q6Q5I7|uniprotkb:D6W2W2|ensemblfungi:YOR261C intact:EBI-15944|uniprotkb:D6VT56|ensemblfungi:YDR427W psi-mi:rpn8_yeast(display_long)|uniprotkb:RPN8(gene name)|psi-mi:RPN8(display_short)|uniprotkb:O5360(orf name)|uniprotkb:YOR261C(locus name) psi-mi:rpn9_yeast(display_long)|uniprotkb:RPN9(gene name)|psi-mi:RPN9(display_short)|uniprotkb:NAS7(gene name synonym)|uniprotkb:YDR427W(locus name)|uniprotkb:D9461.14(orf name)|uniprotkb:Proteasome non-ATPase subunit 7(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346151|imex:IM-14275-2929 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005787|refseq:NP_014904.3|mint:Q08723|dip:DIP-1574N|ensemblfungi:YOR261C(gene)|ensemblfungi:YOR261C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4O8X|rcsb pdb:4O8Y|rcsb pdb:4OCL|rcsb pdb:4OCM|rcsb pdb:4OCN|rcsb pdb:4OWP|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5U4P|rcsb pdb:5W83|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168 sgd:S000002835|ensemblfungi:YDR427W(gene)|ensemblfungi:YDR427W_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043248"(proteasome assembly)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035298|interpro:IPR036390|interpro:IPR040798|rcsb pdb:2MQW|rcsb pdb:2MR3|rcsb pdb:2MRI|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|refseq:NP_010715.3|dip:DIP-5261N|mint:Q04062 psi-mi:"MI:0469"(intact) crc64:6EE6009545A3D0EF crc64:540F7DF8C23469A1 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kvJ/LyyQGKi5JTh4Fek1kh70jOU559292 rogid:hOAU0IY1VeRlmtX4Dw3MNJybZaE559292 intact-crc:D5C4F7EF84446E1C|rigid:h+6j0nM11Qvek0G0naqMU0QvMN0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12250 uniprotkb:Q08723 intact:EBI-15935|uniprotkb:D6VRK1|ensemblfungi:YDL147W intact:EBI-36176|uniprotkb:Q6Q5I7|uniprotkb:D6W2W2|ensemblfungi:YOR261C psi-mi:rpn5_yeast(display_long)|uniprotkb:RPN5(gene name)|psi-mi:RPN5(display_short)|uniprotkb:NAS5(gene name synonym)|uniprotkb:YDL147W(locus name)|uniprotkb:D1572(orf name)|uniprotkb:Proteasome non-ATPase subunit 5(gene name synonym) psi-mi:rpn8_yeast(display_long)|uniprotkb:RPN8(gene name)|psi-mi:RPN8(display_short)|uniprotkb:O5360(orf name)|uniprotkb:YOR261C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346162|imex:IM-14275-2930 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010134.1|sgd:S000002306|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035297|interpro:IPR036388|interpro:IPR036390|interpro:IPR040134|interpro:IPR040896|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:5ZMR|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:6FVX|ensemblfungi:YDL147W(gene)|ensemblfungi:YDL147W_mRNA(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0000502"(proteasome complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0034515"(proteasome storage granule)|rcsb pdb:6J2C|rcsb pdb:6FVY|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|dip:DIP-1578N|mint:Q12250 sgd:S000005787|refseq:NP_014904.3|mint:Q08723|dip:DIP-1574N|ensemblfungi:YOR261C(gene)|ensemblfungi:YOR261C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4O8X|rcsb pdb:4O8Y|rcsb pdb:4OCL|rcsb pdb:4OCM|rcsb pdb:4OCN|rcsb pdb:4OWP|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5U4P|rcsb pdb:5W83|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168 psi-mi:"MI:0469"(intact) crc64:E5DC7F8E6AE27736 crc64:6EE6009545A3D0EF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:DaeRxapE6TgoZG4emWRb3y12Vfc559292 rogid:kvJ/LyyQGKi5JTh4Fek1kh70jOU559292 intact-crc:4F2B684A6B17CAC2|rigid:5S1prQ4V8GHdcL8HKGUkEMF9n/4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12377 uniprotkb:Q08723 intact:EBI-308|uniprotkb:D6VRQ3|ensemblfungi:YDL097C intact:EBI-36176|uniprotkb:Q6Q5I7|uniprotkb:D6W2W2|ensemblfungi:YOR261C psi-mi:rpn6_yeast(display_long)|uniprotkb:RPN6(gene name)|psi-mi:RPN6(display_short)|uniprotkb:NAS4(gene name synonym)|uniprotkb:YDL097C(locus name)|uniprotkb:D2381(orf name)|uniprotkb:Proteasome non-ATPase subunit 4(gene name synonym) psi-mi:rpn8_yeast(display_long)|uniprotkb:RPN8(gene name)|psi-mi:RPN8(display_short)|uniprotkb:O5360(orf name)|uniprotkb:YOR261C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346173|imex:IM-14275-2931 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010186.1|sgd:S000002255|dip:DIP-1581N|mint:Q12377|ensemblfungi:YDL097C(gene)|ensemblfungi:YDL097C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043248"(proteasome assembly)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR036390|interpro:IPR040773|interpro:IPR040780|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168 sgd:S000005787|refseq:NP_014904.3|mint:Q08723|dip:DIP-1574N|ensemblfungi:YOR261C(gene)|ensemblfungi:YOR261C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4O8X|rcsb pdb:4O8Y|rcsb pdb:4OCL|rcsb pdb:4OCM|rcsb pdb:4OCN|rcsb pdb:4OWP|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5U4P|rcsb pdb:5W83|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168 psi-mi:"MI:0469"(intact) crc64:A8B1F7E6F73A4024 crc64:6EE6009545A3D0EF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Q7d0N0C4nR9dUZHh+zofzWAF/t8559292 rogid:kvJ/LyyQGKi5JTh4Fek1kh70jOU559292 intact-crc:6CEA7417D5B79C24|rigid:UmK3jkFeD05F8D2NbT51xu93mIw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53188 uniprotkb:Q08746 intact:EBI-23731|uniprotkb:D6VUA9|ensemblfungi:YGL029W intact:EBI-16026|uniprotkb:D6W2Z3|ensemblfungi:YOR294W psi-mi:cgr1_yeast(display_long)|uniprotkb:YGL029W(locus name)|uniprotkb:CGR1(gene name)|psi-mi:CGR1(display_short)|uniprotkb:Coiled-coil growth-regulated protein 1(gene name synonym) psi-mi:rrs1_yeast(display_long)|uniprotkb:RRS1(gene name)|psi-mi:RRS1(display_short)|uniprotkb:YOR294W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346184|imex:IM-14275-2932 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011486.1|sgd:S000002997|dip:DIP-5450N|mint:P53188|ensemblfungi:YGL029W(gene)|ensemblfungi:YGL029W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR005579(Cgr1)|rcsb pdb:3JCT|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6YLG|rcsb pdb:6YLH ensemblfungi:YOR294W(gene)|refseq:NP_014937.1|sgd:S000005820|ensemblfungi:YOR294W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR007023(Ribosomal biogenesis regulatory protein)|rcsb pdb:3JCT|rcsb pdb:5A53|rcsb pdb:5WXL|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:7BT6|rcsb pdb:7BTB|dip:DIP-4081N|mint:Q08746 psi-mi:"MI:0469"(intact) - crc64:7DFF6C51DDD2ADD6 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:G7SUf9/XRWXFaYG1LRPoChi6BVA559292 rogid:JyvCj+ru9yzw4WAhTwy+V5dUdxY559292 intact-crc:497413CC4783F984|rigid:MMbIsLJbNRP4NpUQD3eL3MnhvLE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08760 uniprotkb:Q07688 intact:EBI-33657|uniprotkb:D6W300|ensemblfungi:YOR301W intact:EBI-34423|uniprotkb:D6VRC1|ensemblfungi:YDL235C psi-mi:rax1_yeast(display_long)|uniprotkb:RAX1(gene name)|psi-mi:RAX1(display_short)|uniprotkb:Revert to axial protein 1(gene name synonym)|uniprotkb:YOR301W(locus name) psi-mi:ypd1_yeast(display_long)|uniprotkb:YPD1(gene name)|psi-mi:YPD1(display_short)|uniprotkb:Histidine-containing phosphotransfer protein YPD1(gene name synonym)|uniprotkb:Tyrosine phosphatase-dependent protein 1(gene name synonym)|uniprotkb:D0790(orf name)|uniprotkb:YDL235C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346195|imex:IM-14275-2933 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005827|interpro:IPR016137(Regulator of G protein signalling superfamily)|refseq:NP_014945.3|mint:Q08760|interpro:IPR036305|ensemblfungi:YOR301W(gene)|ensemblfungi:YOR301W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005621"(cellular bud scar)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007120"(axial cellular bud site selection)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0008104"(protein localization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034613"(cellular protein localization) refseq:NP_010046.1|sgd:S000002394|mint:Q07688|dip:DIP-5899N|ensemblfungi:YDL235C(gene)|ensemblfungi:YDL235C_mRNA(transcript)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007234"(osmosensory signaling via phosphorelay pathway)|go:"GO:0009927"(histidine phosphotransfer kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016772"(transferase activity, transferring phosphorus-containing groups)|go:"GO:0043424"(protein histidine kinase binding)|interpro:IPR008207("Signal transduction histidine kinase, phosphotransfer (Hpt) region")|interpro:IPR036641|rcsb pdb:1C02|rcsb pdb:1C03|rcsb pdb:1OXB|rcsb pdb:1OXK|rcsb pdb:1QSP|rcsb pdb:2R25|rcsb pdb:5KBX|rcsb pdb:6M7W psi-mi:"MI:0469"(intact) - crc64:4B923E621C57783D figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:APjkGr4TmZFMe49W1oM6wqOBa9g559292 rogid:YN/TB6a79rhT0M1R09pLAyj/Xac559292 intact-crc:D259BE56D5AFF44D|rigid:e1oQqhJUlTeMs1kxlu8pSVkHk7o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:Q08826 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-17603|ensemblfungi:YOR357C|uniprotkb:D6W352 psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:snx3_yeast(display_long)|uniprotkb:SNX3(gene name)|psi-mi:SNX3(display_short)|uniprotkb:GRD19(gene name synonym)|uniprotkb:YOR357C(locus name)|uniprotkb:Golgi retention deficient protein 19(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346206|imex:IM-14275-2934 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 go:"GO:0030904"(retromer complex)|ensemblfungi:YOR357C(gene)|ensemblfungi:YOR357C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032994"(protein-lipid complex)|go:"GO:0034499"(late endosome to Golgi transport)|rcsb pdb:1OCS|rcsb pdb:1OCU|reactome:R-SCE-3238698|reactome:R-SCE-5689880|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|interpro:IPR001683(Phox-like)|sgd:S000005884|interpro:IPR042138|refseq:NP_015002.3|mint:Q08826|interpro:IPR036871 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:d/G9NZa1VdfC1zs03H49a1KMNRg559292 intact-crc:B888137CD9DEF527|rigid:4wOvzKNVqhkrY+d5wsQwXUU2TvQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C268 uniprotkb:Q08926 intact:EBI-2044092|uniprotkb:D6VPV9|ensemblfungi:YBL039W-B intact:EBI-2044051|uniprotkb:D6W3I3|ensemblfungi:YPL186C psi-mi:yb39b_yeast(display_long)|uniprotkb:YBL039W-B(locus name) psi-mi:uip4_yeast(display_long)|uniprotkb:YPL186C(locus name)|uniprotkb:UIP4(gene name)|psi-mi:UIP4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346217|imex:IM-14275-2935 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000028517|refseq:NP_878045.1|mint:P0C268|ensemblfungi:YBL039W-B(gene)|ensemblfungi:YBL039W-B_mRNA(transcript)|go:"GO:0005777"(peroxisome) sgd:S000006107|refseq:NP_015138.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold)|mint:Q08926|ensemblfungi:YPL186C(gene)|ensemblfungi:YPL186C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:EfowKSHyZ6Fgw3vWQ74mzPwXTbQ559292 rogid:jZmXJYN6MQPlKDZXQnkU2tSI7vM559292 intact-crc:2DB831AA2BD2495C|rigid:jDWARDN73xZ5PnsJxRwsSbOKWoc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08926 uniprotkb:P18411 intact:EBI-2044051|uniprotkb:D6W3I3|ensemblfungi:YPL186C intact:EBI-20609|uniprotkb:D6VPL0|ensemblfungi:YAL008W psi-mi:uip4_yeast(display_long)|uniprotkb:YPL186C(locus name)|uniprotkb:UIP4(gene name)|psi-mi:UIP4(display_short) psi-mi:fun14_yeast(display_long)|uniprotkb:FUN14(gene name)|psi-mi:FUN14(display_short)|uniprotkb:YAL008W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346228|imex:IM-14275-2936 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006107|refseq:NP_015138.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold)|mint:Q08926|ensemblfungi:YPL186C(gene)|ensemblfungi:YPL186C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane) go:"GO:0007005"(mitochondrion organization)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0055091"(phospholipid homeostasis)|reactome:R-SCE-8934903|sgd:S000000006|interpro:IPR007014(FUN14)|refseq:NP_009394.1|ensemblfungi:YAL008W_mRNA(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|ensemblfungi:YAL008W(gene)|mint:P18411 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jZmXJYN6MQPlKDZXQnkU2tSI7vM559292 rogid:OzV8V+XMS7qJmUtXubBZUVCgya0559292 intact-crc:E8E0ED9F034FBC73|rigid:J++qgf+UD1JtuEJeBYhiE1ipZjY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38756 uniprotkb:Q08926 intact:EBI-24431|uniprotkb:D3DKU6|ensemblfungi:YHR003C intact:EBI-2044051|uniprotkb:D6W3I3|ensemblfungi:YPL186C psi-mi:tcd1_yeast(display_long)|uniprotkb:TCD1(gene name)|psi-mi:TCD1(display_short)|uniprotkb:"t(6)A37 dehydratase 1"(gene name synonym)|uniprotkb:YHR003C(locus name) psi-mi:uip4_yeast(display_long)|uniprotkb:YPL186C(locus name)|uniprotkb:UIP4(gene name)|psi-mi:UIP4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346239|imex:IM-14275-2937 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011866.1|sgd:S000001045|dip:DIP-4417N|mint:P38756|ensemblfungi:YHR003C(gene)|ensemblfungi:YHR003C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008641"(ubiquitin-like modifier activating enzyme activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0061503"(tRNA threonylcarbamoyladenosine dehydratase)|go:"GO:0061504"(cyclic threonylcarbamoyladenosine biosynthetic process)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR035985 sgd:S000006107|refseq:NP_015138.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold)|mint:Q08926|ensemblfungi:YPL186C(gene)|ensemblfungi:YPL186C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Mce7jBtBDJ9bSrw+cQDCbhK8DvY559292 rogid:jZmXJYN6MQPlKDZXQnkU2tSI7vM559292 intact-crc:4E2EB35EE1DB545F|rigid:qYPmZ7aRM663z+pYf+FCtx4MbZQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54783 uniprotkb:Q08926 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 intact:EBI-2044051|uniprotkb:D6W3I3|ensemblfungi:YPL186C psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:uip4_yeast(display_long)|uniprotkb:YPL186C(locus name)|uniprotkb:UIP4(gene name)|psi-mi:UIP4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346250|imex:IM-14275-2938 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 sgd:S000006107|refseq:NP_015138.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold)|mint:Q08926|ensemblfungi:YPL186C(gene)|ensemblfungi:YPL186C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 rogid:jZmXJYN6MQPlKDZXQnkU2tSI7vM559292 intact-crc:DB4373A7DCE7C92B|rigid:w1iu7Gn322dGuazeX5AvMQVX1ds false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08962 uniprotkb:P40078 intact:EBI-12067|uniprotkb:D6W3F9|ensemblfungi:YPL211W intact:EBI-22681|uniprotkb:D3DM32|ensemblfungi:YER126C psi-mi:nip7_yeast(display_long)|uniprotkb:YPL211W(locus name)|uniprotkb:NIP7(gene name)|psi-mi:NIP7(display_short)|uniprotkb:Nuclear import protein 7(gene name synonym) psi-mi:nsa2_yeast(display_long)|uniprotkb:YER126C(locus name)|uniprotkb:SYGP-ORF47(orf name)|uniprotkb:NSA2(gene name)|psi-mi:NSA2(display_short)|uniprotkb:NOP7-associated protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346261|imex:IM-14275-2939 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL211W(gene)|ensemblfungi:YPL211W_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR002478(PUA)|interpro:IPR005155(Ribosome biogenesis factor NIP7-like)|interpro:IPR015947(PUA-like)|interpro:IPR016686(Ribosome biogenesis factor, NIP7)|interpro:IPR036974|interpro:IPR040598|rcsb pdb:6ELZ|go:"GO:0003723"(RNA binding)|rcsb pdb:6EM5|refseq:NP_015113.1|sgd:S000006132|mint:Q08962|dip:DIP-1456N refseq:NP_011052.1|sgd:S000000928|dip:DIP-1892N|mint:P40078|ensemblfungi:YER126C(gene)|ensemblfungi:YER126C_mRNA(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR022309|interpro:IPR039411|rcsb pdb:3JCT|rcsb pdb:4WJV|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:7BT6|rcsb pdb:7BTB psi-mi:"MI:0469"(intact) crc64:82EAE8E4B2FCC31A crc64:545C8B4250BCB0C9 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VVPB1u3oRbh7O35Bzm6G7yHRLsE559292 rogid:ru6dofBbaVkHM+0tunQ4n36y98M559292 intact-crc:6C3CDF50A4218B41|rigid:mHMq840Pyr/Aadbyg+xalfmu5OE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36036 uniprotkb:Q12008 intact:EBI-27015|uniprotkb:D6VWY9|ensemblfungi:YKL214C intact:EBI-2063839|uniprotkb:D6VRW9|ensemblfungi:YDL021W psi-mi:yra2_yeast(display_long)|uniprotkb:YRA2(gene name)|psi-mi:YRA2(display_short)|uniprotkb:YKL214C(locus name) psi-mi:pmg2_yeast(display_long)|uniprotkb:GPM2(gene name)|psi-mi:GPM2(display_short)|uniprotkb:Phosphoglyceromutase 2(gene name synonym)|uniprotkb:MPGM 2(gene name synonym)|uniprotkb:BPG-dependent PGAM 2(gene name synonym)|uniprotkb:D2835(orf name)|uniprotkb:YDL021W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346272|imex:IM-14275-2940 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012708.1|sgd:S000001697|mint:P36036|dip:DIP-6538N|ensemblfungi:YKL214C(gene)|ensemblfungi:YKL214C_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR025715|interpro:IPR034396|interpro:IPR035979 refseq:NP_010263.1|sgd:S000002179|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR005952(Phosphoglycerate mutase 1)|interpro:IPR029033|mint:Q12008|ensemblfungi:YDL021W(gene)|ensemblfungi:YDL021W_mRNA(transcript)|go:"GO:0004619"(phosphoglycerate mutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006096"(glycolytic process) psi-mi:"MI:0469"(intact) crc64:89B7A4B210438652 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ljTu41/hbnu41b/YcuwTYMZOgww559292 rogid:bB/jtZqKH8yay0AmTE70BVposm8559292 intact-crc:1E44A881F27AEEF3|rigid:ele/J9PaHIOHu84Vby9/IflCrDM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6Q5K6 uniprotkb:Q12008 intact:EBI-392766|ensemblfungi:YML058W-A|uniprotkb:D6VZB5 intact:EBI-2063839|uniprotkb:D6VRW9|ensemblfungi:YDL021W psi-mi:hug1_yeast(display_long)|uniprotkb:HUG1(gene name)|psi-mi:HUG1(display_short)|uniprotkb:YML058W-A(locus name) psi-mi:pmg2_yeast(display_long)|uniprotkb:GPM2(gene name)|psi-mi:GPM2(display_short)|uniprotkb:Phosphoglyceromutase 2(gene name synonym)|uniprotkb:MPGM 2(gene name synonym)|uniprotkb:BPG-dependent PGAM 2(gene name synonym)|uniprotkb:D2835(orf name)|uniprotkb:YDL021W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346283|imex:IM-14275-2941 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML058W-A(gene)|ensemblfungi:YML058W-A_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:1905117"(regulation of ribonucleoside-diphosphate reductase activity)|go:"GO:1990846"(ribonucleoside-diphosphate reductase inhibitor activity)|sgd:S000007472|refseq:NP_219498.1|mint:Q6Q5K6 refseq:NP_010263.1|sgd:S000002179|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR005952(Phosphoglycerate mutase 1)|interpro:IPR029033|mint:Q12008|ensemblfungi:YDL021W(gene)|ensemblfungi:YDL021W_mRNA(transcript)|go:"GO:0004619"(phosphoglycerate mutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006096"(glycolytic process) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:x+quBrnP+8yql7JGQ1NK4j5ubbw559292 rogid:bB/jtZqKH8yay0AmTE70BVposm8559292 intact-crc:B140A41CDBD56A4C|rigid:ASV4CRkuu/6vFrYr8bFAUbuBDzE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03370 uniprotkb:Q12020 intact:EBI-36170|uniprotkb:D6VTA2|ensemblfungi:YDR479C intact:EBI-38714|uniprotkb:D6VY82|ensemblfungi:YLR082C psi-mi:pex29_yeast(display_long)|uniprotkb:PEX29(gene name)|psi-mi:PEX29(display_short)|uniprotkb:Peroxin-29(gene name synonym)|uniprotkb:YDR479C(locus name) psi-mi:srl2_yeast(display_long)|uniprotkb:Suppressor of RAD53 null lethality protein 2(gene name synonym)|uniprotkb:SRL2(gene name)|psi-mi:SRL2(display_short)|uniprotkb:YLR082C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346294|imex:IM-14275-2942 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010767.1|sgd:S000002887|mint:Q03370|dip:DIP-5175N|ensemblfungi:YDR479C(gene)|ensemblfungi:YDR479C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032581"(ER-dependent peroxisome organization)|interpro:IPR010482(Integral peroxisomal membrane peroxin) sgd:S000004072|refseq:NP_013183.1|mint:Q12020|dip:DIP-1442N|ensemblfungi:YLR082C(gene)|ensemblfungi:YLR082C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006139"(nucleobase-containing compound metabolic process) psi-mi:"MI:0469"(intact) crc64:C2EB849C36FB69EB crc64:A39CD3D2E0F9BBF3 figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XirbTI20sgYx5DDsELcnS9RLxMw559292 rogid:HVo/JUo9fmmcCD0iLScF47NCDrM559292 intact-crc:8576FFF7401F92CA|rigid:XnU0iigjZF/0uu1Pd716YcF/hOI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12020 uniprotkb:Q08281 intact:EBI-38714|uniprotkb:D6VY82|ensemblfungi:YLR082C intact:EBI-2047093|uniprotkb:D6W1T1|uniprotkb:Q92271|ensemblfungi:YOL138C psi-mi:srl2_yeast(display_long)|uniprotkb:Suppressor of RAD53 null lethality protein 2(gene name synonym)|uniprotkb:SRL2(gene name)|psi-mi:SRL2(display_short)|uniprotkb:YLR082C(locus name) psi-mi:rtc1_yeast(display_long)|uniprotkb:RTC1(gene name)|psi-mi:RTC1(display_short)|uniprotkb:SEA2(gene name synonym)|uniprotkb:SEH-associated protein 2(gene name synonym)|uniprotkb:YOL138C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346305|imex:IM-14275-2943 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004072|refseq:NP_013183.1|mint:Q12020|dip:DIP-1442N|ensemblfungi:YLR082C(gene)|ensemblfungi:YLR082C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006139"(nucleobase-containing compound metabolic process) interpro:IPR037590|refseq:NP_014503.2|sgd:S000005498|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q08281|interpro:IPR036322|ensemblfungi:YOL138C(gene)|ensemblfungi:YOL138C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0035859"(Seh1-associated complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0097042"(extrinsic component of fungal-type vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling) psi-mi:"MI:0469"(intact) crc64:A39CD3D2E0F9BBF3 - figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:HVo/JUo9fmmcCD0iLScF47NCDrM559292 rogid:3k6vZ9TxDj/BcLSmeJdAg45Ri14559292 intact-crc:844C35E8C7BB3FD6|rigid:qqbhIwfQl1E9zA/3/FtAg6z+A1w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12028 uniprotkb:P22137 intact:EBI-33025|uniprotkb:D6W439|ensemblfungi:YPR029C intact:EBI-4766|uniprotkb:D6VTU9|ensemblfungi:YGL206C psi-mi:ap1g1_yeast(display_long)|uniprotkb:APL4(gene name)|psi-mi:APL4(display_short)|uniprotkb:Clathrin assembly protein complex 1 gamma large chain(gene name synonym)|uniprotkb:Clathrin assembly protein large gamma chain(gene name synonym)|uniprotkb:Gamma-adaptin(gene name synonym)|uniprotkb:YPR029C(locus name) psi-mi:clh_yeast(display_long)|uniprotkb:CHC1(gene name)|psi-mi:CHC1(display_short)|uniprotkb:YGL206C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346316|imex:IM-14275-2944 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015354.1|sgd:S000006233|mint:Q12028|dip:DIP-3913N|ensemblfungi:YPR029C(gene)|ensemblfungi:YPR029C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030121"(AP-1 adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017107(Adaptor protein complex AP-1, gamma subunit)|reactome:R-SCE-432720 refseq:NP_011309.1|sgd:S000003174|dip:DIP-2279N|mint:P22137|ensemblfungi:YGL206C(gene)|ensemblfungi:YGL206C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0071439"(clathrin complex)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-432720|reactome:R-SCE-437239|reactome:R-SCE-8856828|reactome:R-SCE-8866427|reactome:R-SCE-8964038 psi-mi:"MI:0469"(intact) crc64:ABB619E9DC4F565C crc64:622F3083DF2FE315 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nzjklmQlRHNY/Wqmrg6GbLG17e8559292 rogid:SAN6H3nVFozXZyTiRLaljMcIKIA559292 intact-crc:4B52F8F8624C3185|rigid:uN0HGnbCL/SdhvAYLiczo99ccW4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12028 uniprotkb:P35181 intact:EBI-33025|uniprotkb:D6W439|ensemblfungi:YPR029C intact:EBI-2612|uniprotkb:D6VYH5|ensemblfungi:YLR170C psi-mi:ap1g1_yeast(display_long)|uniprotkb:APL4(gene name)|psi-mi:APL4(display_short)|uniprotkb:Clathrin assembly protein complex 1 gamma large chain(gene name synonym)|uniprotkb:Clathrin assembly protein large gamma chain(gene name synonym)|uniprotkb:Gamma-adaptin(gene name synonym)|uniprotkb:YPR029C(locus name) psi-mi:ap1s1_yeast(display_long)|uniprotkb:APS1(gene name)|psi-mi:APS1(display_short)|uniprotkb:YAP19(gene name synonym)|uniprotkb:YLR170C(locus name)|uniprotkb:L9470.16(orf name)|uniprotkb:Sigma1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor AP-1 19 kDa adaptin(gene name synonym)|uniprotkb:HA1 19 kDa subunit(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP19(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP19(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 sigma-1 small chain(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346327|imex:IM-14275-2945 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015354.1|sgd:S000006233|mint:Q12028|dip:DIP-3913N|ensemblfungi:YPR029C(gene)|ensemblfungi:YPR029C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030121"(AP-1 adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017107(Adaptor protein complex AP-1, gamma subunit)|reactome:R-SCE-432720 refseq:NP_013271.1|sgd:S000004160|dip:DIP-4806N|mint:P35181|ensemblfungi:YLR170C(gene)|ensemblfungi:YLR170C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030121"(AP-1 adaptor complex)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000804(Clathrin adaptor, sigma subunit/coatomer, zeta subunit)|interpro:IPR011012(Longin-like)|interpro:IPR016635(Adaptor protein complex, sigma subunit)|interpro:IPR022775|interpro:IPR044733|reactome:R-SCE-432720 psi-mi:"MI:0469"(intact) crc64:ABB619E9DC4F565C crc64:1A584883F1DF815D figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nzjklmQlRHNY/Wqmrg6GbLG17e8559292 rogid:MSl/Rj/unUQm0HSBgFC1jyYJpBM559292 intact-crc:49BC88FBA4753955|rigid:BGCGpIuY1i3ivUdULshZXcW4kI0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12028 uniprotkb:P36000 intact:EBI-33025|uniprotkb:D6W439|ensemblfungi:YPR029C intact:EBI-2206|uniprotkb:D6VX61|ensemblfungi:YKL135C psi-mi:ap1g1_yeast(display_long)|uniprotkb:APL4(gene name)|psi-mi:APL4(display_short)|uniprotkb:Clathrin assembly protein complex 1 gamma large chain(gene name synonym)|uniprotkb:Clathrin assembly protein large gamma chain(gene name synonym)|uniprotkb:Gamma-adaptin(gene name synonym)|uniprotkb:YPR029C(locus name) psi-mi:ap1b1_yeast(display_long)|uniprotkb:APL2(gene name)|psi-mi:APL2(display_short)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta-1 large chain(gene name synonym)|uniprotkb:Clathrin assembly protein large beta-1 chain(gene name synonym)|uniprotkb:YKL135C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346338|imex:IM-14275-2946 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015354.1|sgd:S000006233|mint:Q12028|dip:DIP-3913N|ensemblfungi:YPR029C(gene)|ensemblfungi:YPR029C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030121"(AP-1 adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017107(Adaptor protein complex AP-1, gamma subunit)|reactome:R-SCE-432720 refseq:NP_012787.1|sgd:S000001618|dip:DIP-1199N|mint:P36000|ensemblfungi:YKL135C(gene)|ensemblfungi:YKL135C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030121"(AP-1 adaptor complex)|go:"GO:0030276"(clathrin binding)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|reactome:R-SCE-432720|reactome:R-SCE-437239|reactome:R-SCE-8856825|reactome:R-SCE-8856828|reactome:R-SCE-8866427|reactome:R-SCE-8964038 psi-mi:"MI:0469"(intact) crc64:ABB619E9DC4F565C crc64:89893945D4EC6C4A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nzjklmQlRHNY/Wqmrg6GbLG17e8559292 rogid:MKH8RySJV469TEWyuJCOuAitkJY559292 intact-crc:4B58DA8C3CE3DD6B|rigid:es7n1IMBECE08pELrR+v7RU7bDA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38817 uniprotkb:Q12028 intact:EBI-7569|uniprotkb:D3DL58|ensemblfungi:YHR108W intact:EBI-33025|uniprotkb:D6W439|ensemblfungi:YPR029C psi-mi:gga2_yeast(display_long)|uniprotkb:YHR108W(locus name)|uniprotkb:GGA2(gene name)|psi-mi:GGA2(display_short)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 2(gene name synonym) psi-mi:ap1g1_yeast(display_long)|uniprotkb:APL4(gene name)|psi-mi:APL4(display_short)|uniprotkb:Clathrin assembly protein complex 1 gamma large chain(gene name synonym)|uniprotkb:Clathrin assembly protein large gamma chain(gene name synonym)|uniprotkb:Gamma-adaptin(gene name synonym)|uniprotkb:YPR029C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346349|imex:IM-14275-2947 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011976.1|sgd:S000001150|mint:P38817|dip:DIP-2971N|ensemblfungi:YHR108W(gene)|ensemblfungi:YHR108W_mRNA(transcript)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|rcsb pdb:3MNM refseq:NP_015354.1|sgd:S000006233|mint:Q12028|dip:DIP-3913N|ensemblfungi:YPR029C(gene)|ensemblfungi:YPR029C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030121"(AP-1 adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017107(Adaptor protein complex AP-1, gamma subunit)|reactome:R-SCE-432720 psi-mi:"MI:0469"(intact) crc64:7AC3A317AEE302E2 crc64:ABB619E9DC4F565C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:stplLxS8A9T/NqdjQXRVJTxnRsI559292 rogid:nzjklmQlRHNY/Wqmrg6GbLG17e8559292 intact-crc:37B3CADD0A17B895|rigid:sxC8XeFz4TjSJoF5Gbi8+R1YhEg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39526 uniprotkb:Q12028 intact:EBI-26235|uniprotkb:D6VVY7|ensemblfungi:YJL207C intact:EBI-33025|uniprotkb:D6W439|ensemblfungi:YPR029C psi-mi:laa1_yeast(display_long)|uniprotkb:YJL207C(locus name)|uniprotkb:J0312(orf name)|uniprotkb:HRD550(orf name)|uniprotkb:LAA1(gene name)|psi-mi:LAA1(display_short)|uniprotkb:Large AP-1 accessory protein 1(gene name synonym) psi-mi:ap1g1_yeast(display_long)|uniprotkb:APL4(gene name)|psi-mi:APL4(display_short)|uniprotkb:Clathrin assembly protein complex 1 gamma large chain(gene name synonym)|uniprotkb:Clathrin assembly protein large gamma chain(gene name synonym)|uniprotkb:Gamma-adaptin(gene name synonym)|uniprotkb:YPR029C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346360|imex:IM-14275-2948 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012328.1|sgd:S000003743|mint:P39526|dip:DIP-6552N|ensemblfungi:YJL207C(gene)|ensemblfungi:YJL207C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040108|go:"GO:0005794"(Golgi apparatus) refseq:NP_015354.1|sgd:S000006233|mint:Q12028|dip:DIP-3913N|ensemblfungi:YPR029C(gene)|ensemblfungi:YPR029C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030121"(AP-1 adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017107(Adaptor protein complex AP-1, gamma subunit)|reactome:R-SCE-432720 psi-mi:"MI:0469"(intact) crc64:6A296796F2FA5791 crc64:ABB619E9DC4F565C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TBU2esGF5bm0Y2oSCPaGv6PzNfs559292 rogid:nzjklmQlRHNY/Wqmrg6GbLG17e8559292 intact-crc:E8C7C8B8BA9A0D91|rigid:KVYexFaEOXVzqCMpL074K0Yv7+k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47160 uniprotkb:Q12028 intact:EBI-25662|uniprotkb:D6VWU4|ensemblfungi:YJR125C intact:EBI-33025|uniprotkb:D6W439|ensemblfungi:YPR029C psi-mi:ent3_yeast(display_long)|uniprotkb:ENT3(gene name)|psi-mi:ENT3(display_short)|uniprotkb:J2048(orf name)|uniprotkb:YJR125C(locus name) psi-mi:ap1g1_yeast(display_long)|uniprotkb:APL4(gene name)|psi-mi:APL4(display_short)|uniprotkb:Clathrin assembly protein complex 1 gamma large chain(gene name synonym)|uniprotkb:Clathrin assembly protein large gamma chain(gene name synonym)|uniprotkb:Gamma-adaptin(gene name synonym)|uniprotkb:YPR029C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346371|imex:IM-14275-2949 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012659.1|sgd:S000003886|mint:P47160|dip:DIP-1304N|ensemblfungi:YJR125C(gene)|ensemblfungi:YJR125C_mRNA(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:3ONK|rcsb pdb:3ONL|reactome:R-SCE-8856825 refseq:NP_015354.1|sgd:S000006233|mint:Q12028|dip:DIP-3913N|ensemblfungi:YPR029C(gene)|ensemblfungi:YPR029C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030121"(AP-1 adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017107(Adaptor protein complex AP-1, gamma subunit)|reactome:R-SCE-432720 psi-mi:"MI:0469"(intact) crc64:D666ECB1C0D074FE crc64:ABB619E9DC4F565C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XSl8ItoXxrzs1OsGoIvQ8lBstQQ559292 rogid:nzjklmQlRHNY/Wqmrg6GbLG17e8559292 intact-crc:353EAC61006871E1|rigid:Zb8GLGZhXfOtidlMmjouGgo90Kc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12028 uniprotkb:Q12028 intact:EBI-33025|uniprotkb:D6W439|ensemblfungi:YPR029C intact:EBI-33025|uniprotkb:D6W439|ensemblfungi:YPR029C psi-mi:ap1g1_yeast(display_long)|uniprotkb:APL4(gene name)|psi-mi:APL4(display_short)|uniprotkb:Clathrin assembly protein complex 1 gamma large chain(gene name synonym)|uniprotkb:Clathrin assembly protein large gamma chain(gene name synonym)|uniprotkb:Gamma-adaptin(gene name synonym)|uniprotkb:YPR029C(locus name) psi-mi:ap1g1_yeast(display_long)|uniprotkb:APL4(gene name)|psi-mi:APL4(display_short)|uniprotkb:Clathrin assembly protein complex 1 gamma large chain(gene name synonym)|uniprotkb:Clathrin assembly protein large gamma chain(gene name synonym)|uniprotkb:Gamma-adaptin(gene name synonym)|uniprotkb:YPR029C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346382|imex:IM-14275-2950 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015354.1|sgd:S000006233|mint:Q12028|dip:DIP-3913N|ensemblfungi:YPR029C(gene)|ensemblfungi:YPR029C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030121"(AP-1 adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017107(Adaptor protein complex AP-1, gamma subunit)|reactome:R-SCE-432720 refseq:NP_015354.1|sgd:S000006233|mint:Q12028|dip:DIP-3913N|ensemblfungi:YPR029C(gene)|ensemblfungi:YPR029C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030121"(AP-1 adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017107(Adaptor protein complex AP-1, gamma subunit)|reactome:R-SCE-432720 psi-mi:"MI:0469"(intact) crc64:ABB619E9DC4F565C crc64:ABB619E9DC4F565C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nzjklmQlRHNY/Wqmrg6GbLG17e8559292 rogid:nzjklmQlRHNY/Wqmrg6GbLG17e8559292 intact-crc:D2E4DD35ED59CA39|rigid:YACphR2chvwsidevGINZ3QM1/3w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35732 uniprotkb:Q12034 intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C intact:EBI-17335|uniprotkb:D6VTD6|uniprotkb:E9P8Z6|ensemblfungi:YDR515W psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:slf1_yeast(display_long)|uniprotkb:D9719.20(orf name)|uniprotkb:YDR515W(locus name)|uniprotkb:SLF1(gene name)|psi-mi:SLF1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346393|imex:IM-14275-2951 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 refseq:NP_010803.3|sgd:S000002923|ensemblfungi:YDR515W(gene)|ensemblfungi:YDR515W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|dip:DIP-2938N|mint:Q12034 psi-mi:"MI:0469"(intact) crc64:05734E2D0B7389AC - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 rogid:XBjQud6beJKzvJeWksARACuczoY559292 intact-crc:A4070084D59E2746|rigid:m9XTovrIP3B3MePrvYlgvSZoYEE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12043 uniprotkb:Q12043 intact:EBI-34845|uniprotkb:Q7LH13|uniprotkb:D6W2E4|ensemblfungi:YOR081C intact:EBI-34845|uniprotkb:Q7LH13|uniprotkb:D6W2E4|ensemblfungi:YOR081C psi-mi:tgl5_yeast(display_long)|uniprotkb:TGL5(gene name)|psi-mi:TGL5(display_short)|uniprotkb:STC2(gene name synonym)|uniprotkb:YOR29-32(orf name)|uniprotkb:YOR2964C(orf name)|uniprotkb:YOR081C(locus name)|uniprotkb:Lipase 5(gene name synonym) psi-mi:tgl5_yeast(display_long)|uniprotkb:TGL5(gene name)|psi-mi:TGL5(display_short)|uniprotkb:STC2(gene name synonym)|uniprotkb:YOR29-32(orf name)|uniprotkb:YOR2964C(orf name)|uniprotkb:YOR081C(locus name)|uniprotkb:Lipase 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346404|imex:IM-14275-2952 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014724.1|sgd:S000005607|mint:Q12043|dip:DIP-6280N|ensemblfungi:YOR081C(gene)|ensemblfungi:YOR081C_mRNA(transcript)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042171"(lysophosphatidic acid acyltransferase activity)|interpro:IPR002641(Patatin)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR021771 refseq:NP_014724.1|sgd:S000005607|mint:Q12043|dip:DIP-6280N|ensemblfungi:YOR081C(gene)|ensemblfungi:YOR081C_mRNA(transcript)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042171"(lysophosphatidic acid acyltransferase activity)|interpro:IPR002641(Patatin)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR021771 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ccHxygbWfyyQXKaSbOL4iYhikms559292 rogid:ccHxygbWfyyQXKaSbOL4iYhikms559292 intact-crc:606C3C1C4FF29C21|rigid:ZsEFG3ruDf26aKARIiV2gHBhu/A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:Q12057 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-29838|uniprotkb:D6W2G4|ensemblfungi:YOR104W psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:pin2_yeast(display_long)|uniprotkb:PIN2(gene name)|psi-mi:PIN2(display_short)|uniprotkb:YOR3214W(orf name)|uniprotkb:YOR104W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346415|imex:IM-14275-2953 author score:98.66 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 sgd:S000005630|refseq:NP_014747.1|dip:DIP-4459N|mint:Q12057|ensemblfungi:YOR104W(gene)|ensemblfungi:YOR104W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|interpro:IPR037504 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.66|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:Zk6iUcpP++MEXuhKZ79TMOYQYqM559292 intact-crc:084C8AC0B3A43F08|rigid:xPcY3oZxhQD1FTU6jwp3rmlF4lY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11075 uniprotkb:Q12057 intact:EBI-16882|uniprotkb:Q03960|uniprotkb:Q04139|uniprotkb:D6VSF1|ensemblfungi:YDR170C intact:EBI-29838|uniprotkb:D6W2G4|ensemblfungi:YOR104W psi-mi:sec7_yeast(display_long)|uniprotkb:SEC7(gene name)|psi-mi:SEC7(display_short)|uniprotkb:YD9395.01C(orf name)|uniprotkb:YD9489.05C(orf name)|uniprotkb:YDR170C(locus name) psi-mi:pin2_yeast(display_long)|uniprotkb:PIN2(gene name)|psi-mi:PIN2(display_short)|uniprotkb:YOR3214W(orf name)|uniprotkb:YOR104W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346426|imex:IM-14275-2954 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010454.3|ensemblfungi:YDR170C(gene)|ensemblfungi:YDR170C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005770"(late endosome)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0032012"(regulation of ARF protein signal transduction)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|rcsb pdb:4OIY|go:"GO:0015031"(protein transport)|sgd:S000002577|dip:DIP-830N|mint:P11075 sgd:S000005630|refseq:NP_014747.1|dip:DIP-4459N|mint:Q12057|ensemblfungi:YOR104W(gene)|ensemblfungi:YOR104W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|interpro:IPR037504 psi-mi:"MI:0469"(intact) crc64:02B2D370DD2E4661 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BoKfHXfAHnYKyYGbglgZr/3djRw559292 rogid:Zk6iUcpP++MEXuhKZ79TMOYQYqM559292 intact-crc:5985EC918DD8F341|rigid:XQ2hQ/BQ8Rp8zJHQ4CcqZuJderI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12057 uniprotkb:P29465 intact:EBI-29838|uniprotkb:D6W2G4|ensemblfungi:YOR104W intact:EBI-4632|uniprotkb:D6VQ25|ensemblfungi:YBR023C psi-mi:pin2_yeast(display_long)|uniprotkb:PIN2(gene name)|psi-mi:PIN2(display_short)|uniprotkb:YOR3214W(orf name)|uniprotkb:YOR104W(locus name) psi-mi:chs3_yeast(display_long)|uniprotkb:CHS3(gene name)|psi-mi:CHS3(display_short)|uniprotkb:CAL1(gene name synonym)|uniprotkb:DIT101(gene name synonym)|uniprotkb:KIT2(gene name synonym)|uniprotkb:YBR023C(locus name)|uniprotkb:CSD2(gene name synonym)|uniprotkb:YBR0305(orf name)|uniprotkb:Chitin-UDP acetyl-glucosaminyl transferase 3(gene name synonym)|uniprotkb:Class-IV chitin synthase 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346437|imex:IM-14275-2955 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005630|refseq:NP_014747.1|dip:DIP-4459N|mint:Q12057|ensemblfungi:YOR104W(gene)|ensemblfungi:YOR104W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|interpro:IPR037504 refseq:NP_009579.1|sgd:S000000227|dip:DIP-2482N|mint:P29465|ensemblfungi:YBR023C(gene)|ensemblfungi:YBR023C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0004100"(chitin synthase activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030428"(cell septum)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0045009"(chitosome)|go:"GO:0071944"(cell periphery)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR004835(Fungal chitin synthase)|interpro:IPR029044|rcsb pdb:4WJW psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Zk6iUcpP++MEXuhKZ79TMOYQYqM559292 rogid:8Ik0u35UXSJVtqfgNdo49J+nzFk559292 intact-crc:626810A82A775AD9|rigid:6vQXSkckXECrZW+z3GRnSVoROv8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12057 uniprotkb:P32660 intact:EBI-29838|uniprotkb:D6W2G4|ensemblfungi:YOR104W intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W psi-mi:pin2_yeast(display_long)|uniprotkb:PIN2(gene name)|psi-mi:PIN2(display_short)|uniprotkb:YOR3214W(orf name)|uniprotkb:YOR104W(locus name) psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346448|imex:IM-14275-2956 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005630|refseq:NP_014747.1|dip:DIP-4459N|mint:Q12057|ensemblfungi:YOR104W(gene)|ensemblfungi:YOR104W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|interpro:IPR037504 sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) psi-mi:"MI:0469"(intact) - crc64:3CC3FBA8ADDE8960 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Zk6iUcpP++MEXuhKZ79TMOYQYqM559292 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 intact-crc:DCFF66FA03E1F148|rigid:/D/mmsIvwnwiLrvFVWd4pyeBK8c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:Q12057 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-29838|uniprotkb:D6W2G4|ensemblfungi:YOR104W psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:pin2_yeast(display_long)|uniprotkb:PIN2(gene name)|psi-mi:PIN2(display_short)|uniprotkb:YOR3214W(orf name)|uniprotkb:YOR104W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346459|imex:IM-14275-2957 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N sgd:S000005630|refseq:NP_014747.1|dip:DIP-4459N|mint:Q12057|ensemblfungi:YOR104W(gene)|ensemblfungi:YOR104W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|interpro:IPR037504 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:Zk6iUcpP++MEXuhKZ79TMOYQYqM559292 intact-crc:27E39D6123634307|rigid:mc4K4QTXuwqmQ8R7KRf6nHTsvbM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12057 uniprotkb:P39524 intact:EBI-29838|uniprotkb:D6W2G4|ensemblfungi:YOR104W intact:EBI-3106|uniprotkb:D6VPJ2|ensemblfungi:YAL026C psi-mi:pin2_yeast(display_long)|uniprotkb:PIN2(gene name)|psi-mi:PIN2(display_short)|uniprotkb:YOR3214W(orf name)|uniprotkb:YOR104W(locus name) psi-mi:atc3_yeast(display_long)|uniprotkb:DRS2(gene name)|psi-mi:DRS2(display_short)|uniprotkb:FUN38(orf name)|uniprotkb:YAL026C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346470|imex:IM-14275-2958 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005630|refseq:NP_014747.1|dip:DIP-4459N|mint:Q12057|ensemblfungi:YOR104W(gene)|ensemblfungi:YOR104W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|interpro:IPR037504 refseq:NP_009376.2|sgd:S000000024|dip:DIP-2216N|mint:P39524|ensemblfungi:YAL026C(gene)|ensemblfungi:YAL026C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|go:"GO:1990530"(Cdc50p-Drs2p complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:6PSX|rcsb pdb:6PSY|rcsb pdb:6ROH|rcsb pdb:6ROI|rcsb pdb:6ROJ|rcsb pdb:7OH4|rcsb pdb:7OH5|rcsb pdb:7OH6|rcsb pdb:7OH7|reactome:R-SCE-6798695|reactome:R-SCE-936837 psi-mi:"MI:0469"(intact) - crc64:5745B92901F8E1AE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Zk6iUcpP++MEXuhKZ79TMOYQYqM559292 rogid:qJ8uK7dznIqyjVwjbw/VGn5Bo+4559292 intact-crc:5FBE8F43E4FF9987|rigid:2rJIMkCxH9dCSxWbPVlXJLYICqI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39719 uniprotkb:Q12057 intact:EBI-20703|uniprotkb:Q05165|uniprotkb:D6VPG5|ensemblfungi:YAL053W intact:EBI-29838|uniprotkb:D6W2G4|ensemblfungi:YOR104W psi-mi:flc2_yeast(display_long)|uniprotkb:YAL053W(locus name)|uniprotkb:FLC2(gene name)|psi-mi:FLC2(display_short)|uniprotkb:FAD transporter 2(gene name synonym)|uniprotkb:TRP-like ion channel FLC2(gene name synonym) psi-mi:pin2_yeast(display_long)|uniprotkb:PIN2(gene name)|psi-mi:PIN2(display_short)|uniprotkb:YOR3214W(orf name)|uniprotkb:YOR104W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346481|imex:IM-14275-2959 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009348.2|sgd:S000000049|ensemblfungi:YAL053W(gene)|ensemblfungi:YAL053W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241|go:"GO:0055085"(transmembrane transport)|dip:DIP-6708N|mint:P39719 sgd:S000005630|refseq:NP_014747.1|dip:DIP-4459N|mint:Q12057|ensemblfungi:YOR104W(gene)|ensemblfungi:YOR104W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|interpro:IPR037504 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:NOmMW54DNa0o7vM945DlZgVUy44559292 rogid:Zk6iUcpP++MEXuhKZ79TMOYQYqM559292 intact-crc:CEC34D704A625286|rigid:ACqNYlAodIX1IXkmvv48B4oR6NE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12057 uniprotkb:P43556 intact:EBI-29838|uniprotkb:D6W2G4|ensemblfungi:YOR104W intact:EBI-22845|uniprotkb:D6VTI3|ensemblfungi:YFL047W psi-mi:pin2_yeast(display_long)|uniprotkb:PIN2(gene name)|psi-mi:PIN2(display_short)|uniprotkb:YOR3214W(orf name)|uniprotkb:YOR104W(locus name) psi-mi:rgd2_yeast(display_long)|uniprotkb:RGD2(gene name)|psi-mi:RGD2(display_short)|uniprotkb:YFL047W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346492|imex:IM-14275-2960 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005630|refseq:NP_014747.1|dip:DIP-4459N|mint:Q12057|ensemblfungi:YOR104W(gene)|ensemblfungi:YOR104W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|interpro:IPR037504 refseq:NP_428268.1|sgd:S000001847|dip:DIP-4958N|mint:P43556|go:"GO:0005935"(cellular bud neck)|interpro:IPR031160|reactome:R-SCE-8856828|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0032153"(cell division site)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|ensemblfungi:YFL047W(gene)|ensemblfungi:YFL047W_mRNA(transcript)|go:"GO:0000935"(division septum)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip) psi-mi:"MI:0469"(intact) - crc64:52CF174C5F650157 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Zk6iUcpP++MEXuhKZ79TMOYQYqM559292 rogid:TaphLAmYObi9RXMbE2tJDrHtVxA559292 intact-crc:EBA2D20CA63EE944|rigid:mtWxnZOjgr525p2UD0j2JzytZiA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53277 uniprotkb:Q12057 intact:EBI-23308|uniprotkb:D6VUR1|ensemblfungi:YGR129W intact:EBI-29838|uniprotkb:D6W2G4|ensemblfungi:YOR104W psi-mi:syf2_yeast(display_long)|uniprotkb:SYF2(gene name)|psi-mi:SYF2(display_short)|uniprotkb:NTC31(gene name synonym)|uniprotkb:Synthetic lethal with CDC40 protein 2(gene name synonym)|uniprotkb:PRP19 complex protein 31(gene name synonym)|uniprotkb:YGR129W(locus name) psi-mi:pin2_yeast(display_long)|uniprotkb:PIN2(gene name)|psi-mi:PIN2(display_short)|uniprotkb:YOR3214W(orf name)|uniprotkb:YOR104W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346503|imex:IM-14275-2961 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003361|refseq:NP_011645.3|dip:DIP-1684N|mint:P53277|interpro:IPR013260(mRNA splicing factor SYF2)|ensemblfungi:YGR129W(gene)|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|ensemblfungi:YGR129W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex) sgd:S000005630|refseq:NP_014747.1|dip:DIP-4459N|mint:Q12057|ensemblfungi:YOR104W(gene)|ensemblfungi:YOR104W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|interpro:IPR037504 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:uVAPXi98XAE2k7IPXvd4d+KNknw559292 rogid:Zk6iUcpP++MEXuhKZ79TMOYQYqM559292 intact-crc:73510BE77322B05E|rigid:qnO968AOZWA09rrwjQrBEAk5gSo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38775 uniprotkb:Q12091 intact:EBI-24520|uniprotkb:D3DKZ3|ensemblfungi:YHR045W intact:EBI-5554|uniprotkb:D6W3J8|ensemblfungi:YPL170W psi-mi:yhk5_yeast(display_long)|uniprotkb:YHR045W(locus name) psi-mi:dap1_yeast(display_long)|uniprotkb:P2515(orf name)|uniprotkb:YPL170W(locus name)|uniprotkb:DAP1(gene name)|psi-mi:DAP1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346514|imex:IM-14275-2962 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001087|refseq:NP_011911.1|dip:DIP-5587N|mint:P38775|ensemblfungi:YHR045W(gene)|ensemblfungi:YHR045W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane) refseq:NP_015155.1|sgd:S000006091|dip:DIP-5226N|mint:Q12091|ensemblfungi:YPL170W(gene)|ensemblfungi:YPL170W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0020037"(heme binding)|go:"GO:0032443"(regulation of ergosterol biosynthetic process)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400 psi-mi:"MI:0469"(intact) - crc64:3E3CAC2403C3246F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:DIfjsK4iO1b4tmBBj9gsbfGBAoE559292 rogid:U8eq1aWComURSl2PLysV8lJTxUA559292 intact-crc:E26EB4873A465603|rigid:HjUcZqbFCyyBHs5lgyM6bzrKHV0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12114 uniprotkb:P09620 intact:EBI-4640|uniprotkb:D6VYX2|ensemblfungi:YLR330W intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 psi-mi:chs5_yeast(display_long)|uniprotkb:CHS5(gene name)|psi-mi:CHS5(display_short)|uniprotkb:CAL3(gene name synonym)|uniprotkb:YLR330W(locus name)|uniprotkb:L8543.18(orf name)|uniprotkb:Protein CAL3(gene name synonym) psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346525|imex:IM-14275-2963 author score:96.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013434.1|sgd:S000004322|dip:DIP-8073N|mint:Q12114|ensemblfungi:YLR330W(gene)|ensemblfungi:YLR330W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006039"(cell wall chitin catabolic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034044"(exomer complex)|go:"GO:0043332"(mating projection tip)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001357(BRCT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031669|interpro:IPR031673|interpro:IPR036116|interpro:IPR036420|rcsb pdb:4IN3|rcsb pdb:4WJW|rcsb pdb:4YG8 ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 psi-mi:"MI:0469"(intact) crc64:FA92741B862814C2 - figure legend:tables S3 and S4|author-confidence:96.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iHvfW3fNLv3HLj4Ihya1Vyt0X7I559292 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 intact-crc:12AF5EEF46292978|rigid:O7sRg3FZ55zrJQ/FEKB5PWtueW4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12114 uniprotkb:P11075 intact:EBI-4640|uniprotkb:D6VYX2|ensemblfungi:YLR330W intact:EBI-16882|uniprotkb:Q03960|uniprotkb:Q04139|uniprotkb:D6VSF1|ensemblfungi:YDR170C psi-mi:chs5_yeast(display_long)|uniprotkb:CHS5(gene name)|psi-mi:CHS5(display_short)|uniprotkb:CAL3(gene name synonym)|uniprotkb:YLR330W(locus name)|uniprotkb:L8543.18(orf name)|uniprotkb:Protein CAL3(gene name synonym) psi-mi:sec7_yeast(display_long)|uniprotkb:SEC7(gene name)|psi-mi:SEC7(display_short)|uniprotkb:YD9395.01C(orf name)|uniprotkb:YD9489.05C(orf name)|uniprotkb:YDR170C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346536|imex:IM-14275-2964 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013434.1|sgd:S000004322|dip:DIP-8073N|mint:Q12114|ensemblfungi:YLR330W(gene)|ensemblfungi:YLR330W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006039"(cell wall chitin catabolic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034044"(exomer complex)|go:"GO:0043332"(mating projection tip)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001357(BRCT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031669|interpro:IPR031673|interpro:IPR036116|interpro:IPR036420|rcsb pdb:4IN3|rcsb pdb:4WJW|rcsb pdb:4YG8 refseq:NP_010454.3|ensemblfungi:YDR170C(gene)|ensemblfungi:YDR170C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005770"(late endosome)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0032012"(regulation of ARF protein signal transduction)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|rcsb pdb:4OIY|go:"GO:0015031"(protein transport)|sgd:S000002577|dip:DIP-830N|mint:P11075 psi-mi:"MI:0469"(intact) crc64:FA92741B862814C2 crc64:02B2D370DD2E4661 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iHvfW3fNLv3HLj4Ihya1Vyt0X7I559292 rogid:BoKfHXfAHnYKyYGbglgZr/3djRw559292 intact-crc:43614A6E7075E531|rigid:xuXHJHGtkX3BSavZuslL0eNncgA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32660 uniprotkb:Q12114 intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W intact:EBI-4640|uniprotkb:D6VYX2|ensemblfungi:YLR330W psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:chs5_yeast(display_long)|uniprotkb:CHS5(gene name)|psi-mi:CHS5(display_short)|uniprotkb:CAL3(gene name synonym)|uniprotkb:YLR330W(locus name)|uniprotkb:L8543.18(orf name)|uniprotkb:Protein CAL3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346547|imex:IM-14275-2965 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) refseq:NP_013434.1|sgd:S000004322|dip:DIP-8073N|mint:Q12114|ensemblfungi:YLR330W(gene)|ensemblfungi:YLR330W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006039"(cell wall chitin catabolic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034044"(exomer complex)|go:"GO:0043332"(mating projection tip)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001357(BRCT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031669|interpro:IPR031673|interpro:IPR036116|interpro:IPR036420|rcsb pdb:4IN3|rcsb pdb:4WJW|rcsb pdb:4YG8 psi-mi:"MI:0469"(intact) crc64:3CC3FBA8ADDE8960 crc64:FA92741B862814C2 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 rogid:iHvfW3fNLv3HLj4Ihya1Vyt0X7I559292 intact-crc:C6164365FE4CE738|rigid:ytC46fBARrO6TrdDBp4FEQ5fJps false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12114 uniprotkb:P39526 intact:EBI-4640|uniprotkb:D6VYX2|ensemblfungi:YLR330W intact:EBI-26235|uniprotkb:D6VVY7|ensemblfungi:YJL207C psi-mi:chs5_yeast(display_long)|uniprotkb:CHS5(gene name)|psi-mi:CHS5(display_short)|uniprotkb:CAL3(gene name synonym)|uniprotkb:YLR330W(locus name)|uniprotkb:L8543.18(orf name)|uniprotkb:Protein CAL3(gene name synonym) psi-mi:laa1_yeast(display_long)|uniprotkb:YJL207C(locus name)|uniprotkb:J0312(orf name)|uniprotkb:HRD550(orf name)|uniprotkb:LAA1(gene name)|psi-mi:LAA1(display_short)|uniprotkb:Large AP-1 accessory protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346558|imex:IM-14275-2966 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013434.1|sgd:S000004322|dip:DIP-8073N|mint:Q12114|ensemblfungi:YLR330W(gene)|ensemblfungi:YLR330W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006039"(cell wall chitin catabolic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034044"(exomer complex)|go:"GO:0043332"(mating projection tip)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001357(BRCT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031669|interpro:IPR031673|interpro:IPR036116|interpro:IPR036420|rcsb pdb:4IN3|rcsb pdb:4WJW|rcsb pdb:4YG8 refseq:NP_012328.1|sgd:S000003743|mint:P39526|dip:DIP-6552N|ensemblfungi:YJL207C(gene)|ensemblfungi:YJL207C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040108|go:"GO:0005794"(Golgi apparatus) psi-mi:"MI:0469"(intact) crc64:FA92741B862814C2 crc64:6A296796F2FA5791 figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iHvfW3fNLv3HLj4Ihya1Vyt0X7I559292 rogid:TBU2esGF5bm0Y2oSCPaGv6PzNfs559292 intact-crc:47594DA56211BF73|rigid:wIchG+uTgw2GrxPY2bNSvvBjpnc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12114 uniprotkb:P39719 intact:EBI-4640|uniprotkb:D6VYX2|ensemblfungi:YLR330W intact:EBI-20703|uniprotkb:Q05165|uniprotkb:D6VPG5|ensemblfungi:YAL053W psi-mi:chs5_yeast(display_long)|uniprotkb:CHS5(gene name)|psi-mi:CHS5(display_short)|uniprotkb:CAL3(gene name synonym)|uniprotkb:YLR330W(locus name)|uniprotkb:L8543.18(orf name)|uniprotkb:Protein CAL3(gene name synonym) psi-mi:flc2_yeast(display_long)|uniprotkb:YAL053W(locus name)|uniprotkb:FLC2(gene name)|psi-mi:FLC2(display_short)|uniprotkb:FAD transporter 2(gene name synonym)|uniprotkb:TRP-like ion channel FLC2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346569|imex:IM-14275-2967 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013434.1|sgd:S000004322|dip:DIP-8073N|mint:Q12114|ensemblfungi:YLR330W(gene)|ensemblfungi:YLR330W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006039"(cell wall chitin catabolic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034044"(exomer complex)|go:"GO:0043332"(mating projection tip)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001357(BRCT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031669|interpro:IPR031673|interpro:IPR036116|interpro:IPR036420|rcsb pdb:4IN3|rcsb pdb:4WJW|rcsb pdb:4YG8 refseq:NP_009348.2|sgd:S000000049|ensemblfungi:YAL053W(gene)|ensemblfungi:YAL053W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241|go:"GO:0055085"(transmembrane transport)|dip:DIP-6708N|mint:P39719 psi-mi:"MI:0469"(intact) crc64:FA92741B862814C2 - figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iHvfW3fNLv3HLj4Ihya1Vyt0X7I559292 rogid:NOmMW54DNa0o7vM945DlZgVUy44559292 intact-crc:D4253F9FB67F44F6|rigid:U32Saz3C+Agf8Fuq9rcBCDGviKg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12114 uniprotkb:Q12114 intact:EBI-4640|uniprotkb:D6VYX2|ensemblfungi:YLR330W intact:EBI-4640|uniprotkb:D6VYX2|ensemblfungi:YLR330W psi-mi:chs5_yeast(display_long)|uniprotkb:CHS5(gene name)|psi-mi:CHS5(display_short)|uniprotkb:CAL3(gene name synonym)|uniprotkb:YLR330W(locus name)|uniprotkb:L8543.18(orf name)|uniprotkb:Protein CAL3(gene name synonym) psi-mi:chs5_yeast(display_long)|uniprotkb:CHS5(gene name)|psi-mi:CHS5(display_short)|uniprotkb:CAL3(gene name synonym)|uniprotkb:YLR330W(locus name)|uniprotkb:L8543.18(orf name)|uniprotkb:Protein CAL3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346580|imex:IM-14275-2968 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013434.1|sgd:S000004322|dip:DIP-8073N|mint:Q12114|ensemblfungi:YLR330W(gene)|ensemblfungi:YLR330W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006039"(cell wall chitin catabolic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034044"(exomer complex)|go:"GO:0043332"(mating projection tip)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001357(BRCT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031669|interpro:IPR031673|interpro:IPR036116|interpro:IPR036420|rcsb pdb:4IN3|rcsb pdb:4WJW|rcsb pdb:4YG8 refseq:NP_013434.1|sgd:S000004322|dip:DIP-8073N|mint:Q12114|ensemblfungi:YLR330W(gene)|ensemblfungi:YLR330W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006039"(cell wall chitin catabolic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034044"(exomer complex)|go:"GO:0043332"(mating projection tip)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001357(BRCT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031669|interpro:IPR031673|interpro:IPR036116|interpro:IPR036420|rcsb pdb:4IN3|rcsb pdb:4WJW|rcsb pdb:4YG8 psi-mi:"MI:0469"(intact) crc64:FA92741B862814C2 crc64:FA92741B862814C2 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iHvfW3fNLv3HLj4Ihya1Vyt0X7I559292 rogid:iHvfW3fNLv3HLj4Ihya1Vyt0X7I559292 intact-crc:0E355D0F278BEC12|rigid:8GBH/BhVcFVP1zKu4T5fx08EJxg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48570 uniprotkb:Q12122 intact:EBI-8502|uniprotkb:D6VRH0|ensemblfungi:YDL182W intact:EBI-8508|uniprotkb:E9P8Z7|uniprotkb:D6VRL8|ensemblfungi:YDL131W psi-mi:hosc_yeast(display_long)|uniprotkb:D1298(orf name)|uniprotkb:YDL182W(locus name)|uniprotkb:LYS20(gene name)|psi-mi:LYS20(display_short) psi-mi:hosm_yeast(display_long)|uniprotkb:D2195(orf name)|uniprotkb:YDL131W(locus name)|uniprotkb:LYS21(gene name)|psi-mi:LYS21(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346591|imex:IM-14275-2969 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010099.1|sgd:S000002341|interpro:IPR002034(Alpha-isopropylmalate/homocitrate synthase, conserved site)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR011872(Homocitrate synthase, fungi and archaea)|interpro:IPR000891(Pyruvate carboxyltransferase)|mint:P48570|ensemblfungi:YDL182W(gene)|ensemblfungi:YDL182W_mRNA(transcript)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0004410"(homocitrate synthase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0019878"(lysine biosynthetic process via aminoadipic acid)|go:"GO:0046872"(metal ion binding) refseq:NP_010151.1|sgd:S000002289|dip:DIP-4634N|mint:Q12122|ensemblfungi:YDL131W(gene)|ensemblfungi:YDL131W_mRNA(transcript)|go:"GO:0004410"(homocitrate synthase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0019878"(lysine biosynthetic process via aminoadipic acid)|go:"GO:0046872"(metal ion binding)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR002034(Alpha-isopropylmalate/homocitrate synthase, conserved site)|interpro:IPR011872(Homocitrate synthase, fungi and archaea)|interpro:IPR013785(Aldolase-type TIM barrel) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pD1bQgGuaQ2HwmOCaXyXo/i1IvQ559292 rogid:XA2Z9ramCU3LX1hQw31rwIRjlk8559292 intact-crc:F206CF8A6BABACBC|rigid:6mI0RG75yctvdM6G3w5uvEG2Ca0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12122 uniprotkb:Q12122 intact:EBI-8508|uniprotkb:E9P8Z7|uniprotkb:D6VRL8|ensemblfungi:YDL131W intact:EBI-8508|uniprotkb:E9P8Z7|uniprotkb:D6VRL8|ensemblfungi:YDL131W psi-mi:hosm_yeast(display_long)|uniprotkb:D2195(orf name)|uniprotkb:YDL131W(locus name)|uniprotkb:LYS21(gene name)|psi-mi:LYS21(display_short) psi-mi:hosm_yeast(display_long)|uniprotkb:D2195(orf name)|uniprotkb:YDL131W(locus name)|uniprotkb:LYS21(gene name)|psi-mi:LYS21(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346602|imex:IM-14275-2970 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010151.1|sgd:S000002289|dip:DIP-4634N|mint:Q12122|ensemblfungi:YDL131W(gene)|ensemblfungi:YDL131W_mRNA(transcript)|go:"GO:0004410"(homocitrate synthase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0019878"(lysine biosynthetic process via aminoadipic acid)|go:"GO:0046872"(metal ion binding)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR002034(Alpha-isopropylmalate/homocitrate synthase, conserved site)|interpro:IPR011872(Homocitrate synthase, fungi and archaea)|interpro:IPR013785(Aldolase-type TIM barrel) refseq:NP_010151.1|sgd:S000002289|dip:DIP-4634N|mint:Q12122|ensemblfungi:YDL131W(gene)|ensemblfungi:YDL131W_mRNA(transcript)|go:"GO:0004410"(homocitrate synthase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0019878"(lysine biosynthetic process via aminoadipic acid)|go:"GO:0046872"(metal ion binding)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR002034(Alpha-isopropylmalate/homocitrate synthase, conserved site)|interpro:IPR011872(Homocitrate synthase, fungi and archaea)|interpro:IPR013785(Aldolase-type TIM barrel) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XA2Z9ramCU3LX1hQw31rwIRjlk8559292 rogid:XA2Z9ramCU3LX1hQw31rwIRjlk8559292 intact-crc:0BE0ACDD130EEE2E|rigid:ssC1jUiYHAuOI2T9FlxzDdoM1gE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06144 uniprotkb:Q12127 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W intact:EBI-5303|uniprotkb:D6VYB0|ensemblfungi:YLR110C psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:ccw12_yeast(display_long)|uniprotkb:CCW12(gene name)|psi-mi:CCW12(display_short)|uniprotkb:YLR110C(locus name)|uniprotkb:L9354.7(orf name)|uniprotkb:Protein Alpha0.6(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346613|imex:IM-14275-2971 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 sgd:S000004100|refseq:NP_013211.1|dip:DIP-4570N|mint:Q12127|ensemblfungi:YLR110C(gene)|ensemblfungi:YLR110C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000752"(agglutination involved in conjugation with cellular fusion)|go:"GO:0005199"(structural constituent of cell wall)|go:"GO:0005576"(extracellular region)|go:"GO:0005934"(cellular bud tip)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip)|go:"GO:0071944"(cell periphery)|interpro:IPR025928 psi-mi:"MI:0469"(intact) crc64:2F474503CAB7C195 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 rogid:a43bKccHJ97vpmespaaZH0ADZ8U559292 intact-crc:167C322B4ADCAB8B|rigid:Udk+YOOfsChS5rPHgnFeDBY8cso false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12140 uniprotkb:Q08281 intact:EBI-36401|uniprotkb:D6VRV7|ensemblfungi:YDL037C intact:EBI-2047093|uniprotkb:D6W1T1|uniprotkb:Q92271|ensemblfungi:YOL138C psi-mi:bsc1_yeast(display_long)|uniprotkb:BSC1(gene name)|psi-mi:BSC1(display_short)|uniprotkb:D2734(orf name)|uniprotkb:YDL037C(locus name) psi-mi:rtc1_yeast(display_long)|uniprotkb:RTC1(gene name)|psi-mi:RTC1(display_short)|uniprotkb:SEA2(gene name synonym)|uniprotkb:SEH-associated protein 2(gene name synonym)|uniprotkb:YOL138C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346624|imex:IM-14275-2972 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002195|refseq:NP_010247.1|mint:Q12140|dip:DIP-5600N|ensemblfungi:YDL037C(gene)|ensemblfungi:YDL037C_mRNA(transcript)|interpro:IPR018789 interpro:IPR037590|refseq:NP_014503.2|sgd:S000005498|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q08281|interpro:IPR036322|ensemblfungi:YOL138C(gene)|ensemblfungi:YOL138C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0035859"(Seh1-associated complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0097042"(extrinsic component of fungal-type vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:SmUACU6i/VlGLn/aQLehbLRAWjg559292 rogid:3k6vZ9TxDj/BcLSmeJdAg45Ri14559292 intact-crc:6CD21DDB184123E7|rigid:Kgu5SQCXkWTgnxkA6onPSkBi1mI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31412 uniprotkb:Q12154 intact:EBI-20260|uniprotkb:D6VXK7|ensemblfungi:YKL080W intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C psi-mi:vatc_yeast(display_long)|uniprotkb:VMA5(gene name)|psi-mi:VMA5(display_short)|uniprotkb:VAT3(gene name synonym)|uniprotkb:VATC(gene name synonym)|uniprotkb:YKL410(orf name)|uniprotkb:YKL080W(locus name)|uniprotkb:Vacuolar proton pump subunit C(gene name synonym)|uniprotkb:V-ATPase 42 kDa subunit(gene name synonym) psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346635|imex:IM-14275-2973 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012843.1|sgd:S000001563|ensemblfungi:YKL080W(gene)|ensemblfungi:YKL080W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004907(ATPase, V1 complex, subunit C)|interpro:IPR036132|rcsb pdb:1U7L|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4DL0|rcsb pdb:4EFA|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-4701N|mint:P31412 refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK psi-mi:"MI:0469"(intact) crc64:0CD1B814046C377E crc64:F795C359B5A4A461 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:NBI0upCB5yxAyMQgccBcLhjZk8s559292 rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292 intact-crc:F69FD78303131D38|rigid:5kPwsVu8p6nCfmzGs4oUhILMNPg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12154 uniprotkb:P53192 intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C intact:EBI-23722|uniprotkb:D6VUB7|ensemblfungi:YGL020C psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym) psi-mi:get1_yeast(display_long)|uniprotkb:YGL020C(locus name)|uniprotkb:GET1(gene name)|psi-mi:GET1(display_short)|uniprotkb:Guided entry of tail-anchored proteins 1(gene name synonym)|uniprotkb:MDM39(gene name synonym)|uniprotkb:Mitochondrial distribution and morphology protein 39(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346646|imex:IM-14275-2974 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK refseq:NP_011495.1|sgd:S000002988|dip:DIP-6309N|mint:P53192|ensemblfungi:YGL020C(gene)|ensemblfungi:YGL020C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|interpro:IPR027538|interpro:IPR028945|interpro:IPR029012|rcsb pdb:3B2E|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3VLC|rcsb pdb:3ZS8 psi-mi:"MI:0469"(intact) crc64:F795C359B5A4A461 crc64:C43DC5928D97DB7D figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292 rogid:QaFQLKAc5Ki1Xjg8uaCsZr1CQJM559292 intact-crc:32B4E8F260EE9004|rigid:SvqCXOdXDr9mlKZEYaDSVrins2M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32445 uniprotkb:Q12171 intact:EBI-15206|uniprotkb:O11851|uniprotkb:D6VR39|ensemblfungi:YCR028C-A intact:EBI-32775|uniprotkb:D6W2K4|ensemblfungi:YOR147W psi-mi:rim1_yeast(display_long)|uniprotkb:RIM1(gene name)|psi-mi:RIM1(display_short)|uniprotkb:YCR028C-A(locus name)|uniprotkb:YCR28C-A(orf name)|uniprotkb:Mitochondrial ssDNA-binding protein(gene name synonym) psi-mi:mdm32_yeast(display_long)|uniprotkb:MDM32(gene name)|psi-mi:MDM32(display_short)|uniprotkb:O3521(orf name)|uniprotkb:YOR147W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346657|imex:IM-14275-2975 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009958.2|sgd:S000007222|ensemblfungi:YCR028C-A_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6CQK|rcsb pdb:6CQM|rcsb pdb:6CQO|ensemblfungi:YCR028C-A(gene)|dip:DIP-7376N|mint:P32445 sgd:S000005673|refseq:NP_014790.4|dip:DIP-2556N|mint:Q12171|ensemblfungi:YOR147W(gene)|ensemblfungi:YOR147W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006873"(cellular ion homeostasis)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0016021"(integral component of membrane)|interpro:IPR012571(Mitochondrial distribution and morphology protein family 31/32, fungi) psi-mi:"MI:0469"(intact) crc64:9F913C2FC9EF6E82 - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I5YyvRta+mmFfo7ih+FBsRlvRx8559292 rogid:EO13jPZJJdt7X/w3pIBuWVA7QSY559292 intact-crc:969BB637D1798973|rigid:3cBi0xDW8ZJ91rb86ldVZ+B/e4A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02772 uniprotkb:Q12172 intact:EBI-14134|ensemblfungi:YJR034W|uniprotkb:D6VWK7 intact:EBI-30785|uniprotkb:D6W2M0|ensemblfungi:YOR162C psi-mi:pt191_yeast(display_long)|uniprotkb:PET191(gene name)|psi-mi:PET191(display_short)|uniprotkb:J1604(orf name)|uniprotkb:YJR034W(locus name) psi-mi:yrr1_yeast(display_long)|uniprotkb:YRR1(gene name)|psi-mi:YRR1(display_short)|uniprotkb:PDR2(gene name synonym)|uniprotkb:O3571(orf name)|uniprotkb:YOR162C(locus name)|uniprotkb:Pleiotropic drug-resistance protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346668|imex:IM-14275-2976 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YJR034W(gene)|ensemblfungi:YJR034W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR018793|refseq:NP_012568.1|sgd:S000003795|mint:Q02772|dip:DIP-1619N sgd:S000005688|refseq:NP_014805.3|dip:DIP-5493N|mint:Q12172|ensemblfungi:YOR162C(gene)|ensemblfungi:YOR162C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR036864 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Y2xXA5HsKzl3I4/DuFs5+mLaJUo559292 rogid:LDcZnfouo5U7lModdmCVnCZpbGE559292 intact-crc:653BB32DC482EF6F|rigid:g5schgsRiOkzg338A+Y0PG8LTzw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39744 uniprotkb:Q12176 intact:EBI-29259|uniprotkb:Q08625|uniprotkb:D6W2R2|ensemblfungi:YOR206W intact:EBI-10944|ensemblfungi:YDR060W|uniprotkb:D6VS46 psi-mi:noc2_yeast(display_long)|uniprotkb:YOX001(orf name)|uniprotkb:YOR206W(locus name)|uniprotkb:NOC2(gene name)|psi-mi:NOC2(display_short) psi-mi:mak21_yeast(display_long)|uniprotkb:MAK21(gene name)|psi-mi:MAK21(display_short)|uniprotkb:YDR060W(locus name)|uniprotkb:D4237(orf name)|uniprotkb:YD9609.14(orf name)|uniprotkb:NOC1(gene name synonym)|uniprotkb:Maintenance of killer protein 21(gene name synonym)|uniprotkb:Nucleolar complex protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346679|imex:IM-14275-2977 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014849.3|sgd:S000005732|dip:DIP-4559N|mint:P39744|ensemblfungi:YOR206W(gene)|ensemblfungi:YOR206W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR005343(Protein of unknown function UPF0120) ensemblfungi:YDR060W(gene)|ensemblfungi:YDR060W_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|interpro:IPR005612(CBF)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040155|sgd:S000002467|refseq:NP_010345.3|mint:Q12176|dip:DIP-4040N psi-mi:"MI:0469"(intact) crc64:48C3B9AE076B9B8F - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:d5I8KJOSG63bZ/Pt+XvKdy/SWws559292 rogid:Y5IkqRgw551Db48w/pnXZm0AtvQ559292 intact-crc:A3716BCA9DE06539|rigid:0+ZJyhGZjF090eDo3EQUivh53Ps false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12178 uniprotkb:Q12178 intact:EBI-6851|uniprotkb:D6W467|ensemblfungi:YPR062W intact:EBI-6851|uniprotkb:D6W467|ensemblfungi:YPR062W psi-mi:fcy1_yeast(display_long)|uniprotkb:FCY1(gene name)|psi-mi:FCY1(display_short)|uniprotkb:Cytosine aminohydrolase(gene name synonym)|uniprotkb:Fluorocytosine resistance protein 1(gene name synonym)|uniprotkb:YP9499.17(orf name)|uniprotkb:YPR062W(locus name) psi-mi:fcy1_yeast(display_long)|uniprotkb:FCY1(gene name)|psi-mi:FCY1(display_short)|uniprotkb:Cytosine aminohydrolase(gene name synonym)|uniprotkb:Fluorocytosine resistance protein 1(gene name synonym)|uniprotkb:YP9499.17(orf name)|uniprotkb:YPR062W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346690|imex:IM-14275-2978 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015387.1|sgd:S000006266|mint:Q12178|dip:DIP-1662N|ensemblfungi:YPR062W(gene)|ensemblfungi:YPR062W_mRNA(transcript)|go:"GO:0004131"(cytosine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008655"(pyrimidine-containing compound salvage)|go:"GO:0019858"(cytosine metabolic process)|go:"GO:0044206"(UMP salvage)|go:"GO:0046087"(cytidine metabolic process)|go:"GO:0102480"(5-fluorocytosine deaminase activity)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:1OX7|rcsb pdb:1P6O|rcsb pdb:1RB7|rcsb pdb:1UAQ|rcsb pdb:1YSB|rcsb pdb:1YSD|rcsb pdb:2O3K refseq:NP_015387.1|sgd:S000006266|mint:Q12178|dip:DIP-1662N|ensemblfungi:YPR062W(gene)|ensemblfungi:YPR062W_mRNA(transcript)|go:"GO:0004131"(cytosine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008655"(pyrimidine-containing compound salvage)|go:"GO:0019858"(cytosine metabolic process)|go:"GO:0044206"(UMP salvage)|go:"GO:0046087"(cytidine metabolic process)|go:"GO:0102480"(5-fluorocytosine deaminase activity)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:1OX7|rcsb pdb:1P6O|rcsb pdb:1RB7|rcsb pdb:1UAQ|rcsb pdb:1YSB|rcsb pdb:1YSD|rcsb pdb:2O3K psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MvPOYoVcWjoQ9SXLHNV0YbtCgco559292 rogid:MvPOYoVcWjoQ9SXLHNV0YbtCgco559292 intact-crc:059EBEAB4E81E86A|rigid:Pc1VbT8jf6TEiUk0/WGQe2S/XuA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12181 uniprotkb:P36152 intact:EBI-37624|uniprotkb:D6W456|ensemblfungi:YPR048W intact:EBI-26482|uniprotkb:D6VXD2|ensemblfungi:YKR071C psi-mi:ndor1_yeast(display_long)|uniprotkb:TAH18(gene name)|psi-mi:TAH18(display_short)|uniprotkb:NADPH-dependent FMN and FAD-containing oxidoreductase(gene name synonym)|uniprotkb:YP9499.06(orf name)|uniprotkb:YPR048W(locus name) psi-mi:dre2_yeast(display_long)|uniprotkb:YKR071C(locus name)|uniprotkb:DRE2(gene name)|psi-mi:DRE2(display_short)|uniprotkb:Anamorsin homolog(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346701|imex:IM-14275-2979 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015373.1|sgd:S000006252|dip:DIP-1688N|mint:Q12181|ensemblfungi:YPR048W(gene)|ensemblfungi:YPR048W_mRNA(transcript)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR028879|interpro:IPR029039|interpro:IPR039261 sgd:S000001779|refseq:NP_012997.3|mint:P36152|dip:DIP-6716N|ensemblfungi:YKR071C(gene)|ensemblfungi:YKR071C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|interpro:IPR007785(Protein of unknown function DUF689)|interpro:IPR031838|rcsb pdb:2KM1 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rMyciB2K1QEFDXSgbMznNQ811ko559292 rogid:0QsPVhkahwln/ULEm8uB6eq4/vc559292 intact-crc:E0300C642C480C26|rigid:VrKNjv+mQVd5Hya5LcisbI33kdA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12189 uniprotkb:Q12189 intact:EBI-15898|uniprotkb:D6W2F6|ensemblfungi:YOR095C intact:EBI-15898|uniprotkb:D6W2F6|ensemblfungi:YOR095C psi-mi:rpia_yeast(display_long)|uniprotkb:RKI1(gene name)|psi-mi:RKI1(display_short)|uniprotkb:YOR095C(locus name)|uniprotkb:YOR3174C(orf name)|uniprotkb:Phosphoriboisomerase(gene name synonym)|uniprotkb:D-ribose-5-phosphate ketol-isomerase(gene name synonym) psi-mi:rpia_yeast(display_long)|uniprotkb:RKI1(gene name)|psi-mi:RKI1(display_short)|uniprotkb:YOR095C(locus name)|uniprotkb:YOR3174C(orf name)|uniprotkb:Phosphoriboisomerase(gene name synonym)|uniprotkb:D-ribose-5-phosphate ketol-isomerase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346712|imex:IM-14275-2980 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014738.1|sgd:S000005621|ensemblfungi:YOR095C(gene)|ensemblfungi:YOR095C_mRNA(transcript)|go:"GO:0004751"(ribose-5-phosphate isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006014"(D-ribose metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0008615"(pyridoxine biosynthetic process)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR004788(Ribose 5-phosphate isomerase)|interpro:IPR037171|rcsb pdb:1XTZ|reactome:R-SCE-71336|dip:DIP-4155N|mint:Q12189 refseq:NP_014738.1|sgd:S000005621|ensemblfungi:YOR095C(gene)|ensemblfungi:YOR095C_mRNA(transcript)|go:"GO:0004751"(ribose-5-phosphate isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006014"(D-ribose metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0008615"(pyridoxine biosynthetic process)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR004788(Ribose 5-phosphate isomerase)|interpro:IPR037171|rcsb pdb:1XTZ|reactome:R-SCE-71336|dip:DIP-4155N|mint:Q12189 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:fZdrH6Xra1su0KcX2WQ7xTo7mnE559292 rogid:fZdrH6Xra1su0KcX2WQ7xTo7mnE559292 intact-crc:306B52E12F03E11E|rigid:Q4dSlWcv7bWpBi2Sc6iwqCh7reI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07278 uniprotkb:Q12199 intact:EBI-9475|ensemblfungi:YIL033C|uniprotkb:D6VVP9 intact:EBI-38123|uniprotkb:D6W449|ensemblfungi:YPR040W psi-mi:kapr_yeast(display_long)|uniprotkb:YIL033C(locus name)|uniprotkb:BCY1(gene name)|psi-mi:BCY1(display_short)|uniprotkb:REG1(gene name synonym)|uniprotkb:SRA1(gene name synonym)|uniprotkb:Bypass of cyclase mutations protein 1(gene name synonym)|uniprotkb:Protein kinase A regulatory subunit(gene name synonym) psi-mi:tip41_yeast(display_long)|uniprotkb:TIP41(gene name)|psi-mi:TIP41(display_short)|uniprotkb:YP3085.04(orf name)|uniprotkb:YPR040W(locus name)|uniprotkb:PP2A phosphatase activator TIP41(gene name synonym)|uniprotkb:TAP42-interacting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346723|imex:IM-14275-2981 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YIL033C(gene)|ensemblfungi:YIL033C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0030552"(cAMP binding)|go:"GO:0036278"(positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0061406"(positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|rcsb pdb:3OF1|rcsb pdb:6XQK|refseq:NP_012231.1|sgd:S000001295|mint:P07278|dip:DIP-551N refseq:NP_015365.1|sgd:S000006244|mint:Q12199|dip:DIP-1609N|ensemblfungi:YPR040W(gene)|ensemblfungi:YPR040W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0031929"(TOR signaling)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007303(TIP41-like protein) psi-mi:"MI:0469"(intact) crc64:6D7D97D8E4340AF3 crc64:7E5E31189983EE9F figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rSJ37UFoFiaHqc/2W5eYNx1qpbg559292 rogid:ZZOMSnTmuHGHHaPz/1/YLe7/9f0559292 intact-crc:B66E71F21E87C841|rigid:3SRgPqjvOyjc3sDgKNKgnsq3Z5g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43612 uniprotkb:Q12199 intact:EBI-16370|ensemblfungi:YFR040W|uniprotkb:Q96VG4|uniprotkb:D6VTS3 intact:EBI-38123|uniprotkb:D6W449|ensemblfungi:YPR040W psi-mi:sa155_yeast(display_long)|uniprotkb:SAP155(gene name)|psi-mi:SAP155(display_short)|uniprotkb:YFR040W(locus name) psi-mi:tip41_yeast(display_long)|uniprotkb:TIP41(gene name)|psi-mi:TIP41(display_short)|uniprotkb:YP3085.04(orf name)|uniprotkb:YPR040W(locus name)|uniprotkb:PP2A phosphatase activator TIP41(gene name synonym)|uniprotkb:TAP42-interacting protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346734|imex:IM-14275-2982 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YFR040W(gene)|ensemblfungi:YFR040W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|reactome:R-SCE-204005|refseq:NP_116698.3|sgd:S000001936|dip:DIP-5852N|mint:P43612 refseq:NP_015365.1|sgd:S000006244|mint:Q12199|dip:DIP-1609N|ensemblfungi:YPR040W(gene)|ensemblfungi:YPR040W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0031929"(TOR signaling)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007303(TIP41-like protein) psi-mi:"MI:0469"(intact) crc64:50CDC17130333022 crc64:7E5E31189983EE9F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:OX+DqsaQW7F5rHzNB2R69wYu6YE559292 rogid:ZZOMSnTmuHGHHaPz/1/YLe7/9f0559292 intact-crc:2D9B61371025C885|rigid:PN8zIGw4NZ5Bp92zxHcEQnO8Wh8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12200 uniprotkb:P25584 intact:EBI-32032|uniprotkb:D6W406|ensemblfungi:YPL006W intact:EBI-21765|uniprotkb:D6VQW1|ensemblfungi:YCL056C psi-mi:npc1_yeast(display_long)|uniprotkb:NCR1(gene name)|psi-mi:NCR1(display_short)|uniprotkb:Niemann-Pick type C-related protein 1(gene name synonym)|uniprotkb:YPL006W(locus name) psi-mi:pex34_yeast(display_long)|uniprotkb:YCL056C(locus name)|uniprotkb:YCL56C(orf name)|uniprotkb:YCL433(orf name)|uniprotkb:PEX34(gene name)|psi-mi:PEX34(display_short)|uniprotkb:Peroxin-34(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346745|imex:IM-14275-2983 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015319.1|sgd:S000005927|interpro:IPR003392(Patched)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR032190|mint:Q12200|ensemblfungi:YPL006W(gene)|ensemblfungi:YPL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0015918"(sterol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032934"(sterol binding)|rcsb pdb:6R4L|reactome:R-SCE-8963678|reactome:R-SCE-8964038 sgd:S000000561|refseq:NP_009875.1|mint:P25584|dip:DIP-2040N|ensemblfungi:YCL056C(gene)|ensemblfungi:YCL056C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization) psi-mi:"MI:0469"(intact) - crc64:6035D449766516A6 figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BwD69opwWC4Bf0+OOCZ8yRxT/pg559292 rogid:IGoLOZeCbBNA4w+BG9mC/vxGfqs559292 intact-crc:196E18B7F07D640E|rigid:SdIOJArtJVPGxdOZDoqQpOu8IZo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12200 uniprotkb:P38929 intact:EBI-32032|uniprotkb:D6W406|ensemblfungi:YPL006W intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W psi-mi:npc1_yeast(display_long)|uniprotkb:NCR1(gene name)|psi-mi:NCR1(display_short)|uniprotkb:Niemann-Pick type C-related protein 1(gene name synonym)|uniprotkb:YPL006W(locus name) psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346756|imex:IM-14275-2984 author score:97.90 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015319.1|sgd:S000005927|interpro:IPR003392(Patched)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR032190|mint:Q12200|ensemblfungi:YPL006W(gene)|ensemblfungi:YPL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0015918"(sterol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032934"(sterol binding)|rcsb pdb:6R4L|reactome:R-SCE-8963678|reactome:R-SCE-8964038 refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837 psi-mi:"MI:0469"(intact) - crc64:5BD9ECFF8508F396 figure legend:tables S3 and S4|author-confidence:97.90|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BwD69opwWC4Bf0+OOCZ8yRxT/pg559292 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 intact-crc:B72A33861E884D2B|rigid:vOTR6Wp5xsVnHecngAvrETBG29I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12200 uniprotkb:Q12038 intact:EBI-32032|uniprotkb:D6W406|ensemblfungi:YPL006W intact:EBI-17573|uniprotkb:D6W442|ensemblfungi:YPR032W psi-mi:npc1_yeast(display_long)|uniprotkb:NCR1(gene name)|psi-mi:NCR1(display_short)|uniprotkb:Niemann-Pick type C-related protein 1(gene name synonym)|uniprotkb:YPL006W(locus name) psi-mi:sro7_yeast(display_long)|uniprotkb:SRO7(gene name)|psi-mi:SRO7(display_short)|uniprotkb:SNI1(gene name synonym)|uniprotkb:YPR032W(locus name)|uniprotkb:YP9367.12(orf name)|uniprotkb:SOP1(gene name synonym)|uniprotkb:Suppressor of RHO3 protein 7(gene name synonym)|uniprotkb:Polarity protein SRO7(gene name synonym)|uniprotkb:Sodium protection protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346767|imex:IM-14275-2985 author score:97.95 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015319.1|sgd:S000005927|interpro:IPR003392(Patched)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR032190|mint:Q12200|ensemblfungi:YPL006W(gene)|ensemblfungi:YPL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0015918"(sterol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032934"(sterol binding)|rcsb pdb:6R4L|reactome:R-SCE-8963678|reactome:R-SCE-8964038 refseq:NP_015357.1|sgd:S000006236|ensemblfungi:YPR032W(gene)|ensemblfungi:YPR032W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045159"(myosin II binding)|go:"GO:0050708"(regulation of protein secretion)|interpro:IPR013905("Lethal giant larvae (Lgl) like, C-terminal")|interpro:IPR036322|rcsb pdb:2OAJ|dip:DIP-2581N|mint:Q12038 psi-mi:"MI:0469"(intact) - crc64:FFB0901883009815 figure legend:tables S3 and S4|author-confidence:97.95|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:BwD69opwWC4Bf0+OOCZ8yRxT/pg559292 rogid:3nYgL2CW3rzKE71MX0MekJKKUlk559292 intact-crc:CD96CF688A0CD6DC|rigid:E8Us2rYPxj7ME6w5hTop/pOJH/Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12206 uniprotkb:Q12206 intact:EBI-20571|uniprotkb:D6W2T3|ensemblfungi:YOR229W intact:EBI-20571|uniprotkb:D6W2T3|ensemblfungi:YOR229W psi-mi:wtm2_yeast(display_long)|uniprotkb:WTM2(gene name)|psi-mi:WTM2(display_short)|uniprotkb:YOR50-19(orf name)|uniprotkb:YOR229W(locus name) psi-mi:wtm2_yeast(display_long)|uniprotkb:WTM2(gene name)|psi-mi:WTM2(display_short)|uniprotkb:YOR50-19(orf name)|uniprotkb:YOR229W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346778|imex:IM-14275-2986 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014872.1|sgd:S000005755|ensemblfungi:YOR229W(gene)|ensemblfungi:YOR229W_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010674"(negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0034629"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-SCE-3214815|reactome:R-SCE-3214847|reactome:R-SCE-3214858|dip:DIP-1534N|mint:Q12206 refseq:NP_014872.1|sgd:S000005755|ensemblfungi:YOR229W(gene)|ensemblfungi:YOR229W_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010674"(negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0034629"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-SCE-3214815|reactome:R-SCE-3214847|reactome:R-SCE-3214858|dip:DIP-1534N|mint:Q12206 psi-mi:"MI:0469"(intact) crc64:4A8F5F879B88AA94 crc64:4A8F5F879B88AA94 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:DCudPHib/PxB5+S+RRONJQyC+QI559292 rogid:DCudPHib/PxB5+S+RRONJQyC+QI559292 intact-crc:FFB632EA296F446F|rigid:v18SWSkoRt5psp3kl/QurkalcDg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10823 uniprotkb:Q12215 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W intact:EBI-20551|uniprotkb:D6W1W1|uniprotkb:Q2VQX5|ensemblfungi:YOL105C psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:wsc3_yeast(display_long)|uniprotkb:WSC3(gene name)|psi-mi:WSC3(display_short)|uniprotkb:HRE556(orf name)|uniprotkb:YOL105C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346789|imex:IM-14275-2987 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 refseq:NP_014536.1|sgd:S000005465|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007266"(Rho protein signal transduction)|ensemblfungi:YOL105C_mRNA(transcript)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0043332"(mating projection tip)|go:"GO:0071555"(cell wall organization)|interpro:IPR002889(Carbohydrate-binding WSC)|go:"GO:0000324"(fungal-type vacuole)|ensemblfungi:YOL105C(gene)|dip:DIP-1748N|mint:Q12215 psi-mi:"MI:0469"(intact) crc64:881B91792AE91748 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rogid:kddySe6TgeL9Jf6tB4TovTn4T7A559292 intact-crc:C34B46F9D193F47D|rigid:cJ5lTgO0GEIcA3wq6zgYYrJ1DVo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12215 uniprotkb:P19807 intact:EBI-20551|uniprotkb:D6W1W1|uniprotkb:Q2VQX5|ensemblfungi:YOL105C intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:wsc3_yeast(display_long)|uniprotkb:WSC3(gene name)|psi-mi:WSC3(display_short)|uniprotkb:HRE556(orf name)|uniprotkb:YOL105C(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346800|imex:IM-14275-2988 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014536.1|sgd:S000005465|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007266"(Rho protein signal transduction)|ensemblfungi:YOL105C_mRNA(transcript)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0043332"(mating projection tip)|go:"GO:0071555"(cell wall organization)|interpro:IPR002889(Carbohydrate-binding WSC)|go:"GO:0000324"(fungal-type vacuole)|ensemblfungi:YOL105C(gene)|dip:DIP-1748N|mint:Q12215 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kddySe6TgeL9Jf6tB4TovTn4T7A559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:EB80D2822D0F4713|rigid:QHvq7dj3cpjpqGCWLO9vjpMeLdU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:Q12215 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-20551|uniprotkb:D6W1W1|uniprotkb:Q2VQX5|ensemblfungi:YOL105C psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:wsc3_yeast(display_long)|uniprotkb:WSC3(gene name)|psi-mi:WSC3(display_short)|uniprotkb:HRE556(orf name)|uniprotkb:YOL105C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346811|imex:IM-14275-2989 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N refseq:NP_014536.1|sgd:S000005465|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007266"(Rho protein signal transduction)|ensemblfungi:YOL105C_mRNA(transcript)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0043332"(mating projection tip)|go:"GO:0071555"(cell wall organization)|interpro:IPR002889(Carbohydrate-binding WSC)|go:"GO:0000324"(fungal-type vacuole)|ensemblfungi:YOL105C(gene)|dip:DIP-1748N|mint:Q12215 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:kddySe6TgeL9Jf6tB4TovTn4T7A559292 intact-crc:234DD073E650653F|rigid:p2Jb6noshD6dXvFsPfiV4SDgpbs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12215 uniprotkb:P38234 intact:EBI-20551|uniprotkb:D6W1W1|uniprotkb:Q2VQX5|ensemblfungi:YOL105C intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C psi-mi:wsc3_yeast(display_long)|uniprotkb:WSC3(gene name)|psi-mi:WSC3(display_short)|uniprotkb:HRE556(orf name)|uniprotkb:YOL105C(locus name) psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346822|imex:IM-14275-2990 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014536.1|sgd:S000005465|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007266"(Rho protein signal transduction)|ensemblfungi:YOL105C_mRNA(transcript)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0043332"(mating projection tip)|go:"GO:0071555"(cell wall organization)|interpro:IPR002889(Carbohydrate-binding WSC)|go:"GO:0000324"(fungal-type vacuole)|ensemblfungi:YOL105C(gene)|dip:DIP-1748N|mint:Q12215 refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kddySe6TgeL9Jf6tB4TovTn4T7A559292 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 intact-crc:C1030A30256EF0F6|rigid:JbyZq1QGmt17nGjMBfhsPwXiI40 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39719 uniprotkb:Q12215 intact:EBI-20703|uniprotkb:Q05165|uniprotkb:D6VPG5|ensemblfungi:YAL053W intact:EBI-20551|uniprotkb:D6W1W1|uniprotkb:Q2VQX5|ensemblfungi:YOL105C psi-mi:flc2_yeast(display_long)|uniprotkb:YAL053W(locus name)|uniprotkb:FLC2(gene name)|psi-mi:FLC2(display_short)|uniprotkb:FAD transporter 2(gene name synonym)|uniprotkb:TRP-like ion channel FLC2(gene name synonym) psi-mi:wsc3_yeast(display_long)|uniprotkb:WSC3(gene name)|psi-mi:WSC3(display_short)|uniprotkb:HRE556(orf name)|uniprotkb:YOL105C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346833|imex:IM-14275-2991 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009348.2|sgd:S000000049|ensemblfungi:YAL053W(gene)|ensemblfungi:YAL053W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241|go:"GO:0055085"(transmembrane transport)|dip:DIP-6708N|mint:P39719 refseq:NP_014536.1|sgd:S000005465|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007266"(Rho protein signal transduction)|ensemblfungi:YOL105C_mRNA(transcript)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0043332"(mating projection tip)|go:"GO:0071555"(cell wall organization)|interpro:IPR002889(Carbohydrate-binding WSC)|go:"GO:0000324"(fungal-type vacuole)|ensemblfungi:YOL105C(gene)|dip:DIP-1748N|mint:Q12215 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:NOmMW54DNa0o7vM945DlZgVUy44559292 rogid:kddySe6TgeL9Jf6tB4TovTn4T7A559292 intact-crc:CA6083028F5174BE|rigid:/PwJxJB4qB3Cm5fHcBgM5tpO2Js false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12215 uniprotkb:P50276 intact:EBI-20551|uniprotkb:D6W1W1|uniprotkb:Q2VQX5|ensemblfungi:YOL105C intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 psi-mi:wsc3_yeast(display_long)|uniprotkb:WSC3(gene name)|psi-mi:WSC3(display_short)|uniprotkb:HRE556(orf name)|uniprotkb:YOL105C(locus name) psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346844|imex:IM-14275-2992 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014536.1|sgd:S000005465|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007266"(Rho protein signal transduction)|ensemblfungi:YOL105C_mRNA(transcript)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0043332"(mating projection tip)|go:"GO:0071555"(cell wall organization)|interpro:IPR002889(Carbohydrate-binding WSC)|go:"GO:0000324"(fungal-type vacuole)|ensemblfungi:YOL105C(gene)|dip:DIP-1748N|mint:Q12215 ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kddySe6TgeL9Jf6tB4TovTn4T7A559292 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 intact-crc:A0FB03420AD803E3|rigid:F523qS+h6G71TgI2lZdSuo85wUg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53832 uniprotkb:Q12215 intact:EBI-2055941|uniprotkb:D6W0R1|ensemblfungi:YNL283C intact:EBI-20551|uniprotkb:D6W1W1|uniprotkb:Q2VQX5|ensemblfungi:YOL105C psi-mi:wsc2_yeast(display_long)|uniprotkb:YNL283C(locus name)|uniprotkb:N0583(orf name)|uniprotkb:WSC2(gene name)|psi-mi:WSC2(display_short) psi-mi:wsc3_yeast(display_long)|uniprotkb:WSC3(gene name)|psi-mi:WSC3(display_short)|uniprotkb:HRE556(orf name)|uniprotkb:YOL105C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346855|imex:IM-14275-2993 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014116.1|sgd:S000005227|interpro:IPR002889(Carbohydrate-binding WSC)|mint:P53832|ensemblfungi:YNL283C(gene)|ensemblfungi:YNL283C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip) refseq:NP_014536.1|sgd:S000005465|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007266"(Rho protein signal transduction)|ensemblfungi:YOL105C_mRNA(transcript)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0043332"(mating projection tip)|go:"GO:0071555"(cell wall organization)|interpro:IPR002889(Carbohydrate-binding WSC)|go:"GO:0000324"(fungal-type vacuole)|ensemblfungi:YOL105C(gene)|dip:DIP-1748N|mint:Q12215 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5wadvTv6SxcIAb60yfnuGMfa8pY559292 rogid:kddySe6TgeL9Jf6tB4TovTn4T7A559292 intact-crc:E5DC58F3EDE71872|rigid:36Tf5dsudEKpNbAXQEvE67KWgSo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12215 uniprotkb:Q02785 intact:EBI-20551|uniprotkb:D6W1W1|uniprotkb:Q2VQX5|ensemblfungi:YOL105C intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:wsc3_yeast(display_long)|uniprotkb:WSC3(gene name)|psi-mi:WSC3(display_short)|uniprotkb:HRE556(orf name)|uniprotkb:YOL105C(locus name) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346866|imex:IM-14275-2994 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014536.1|sgd:S000005465|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007266"(Rho protein signal transduction)|ensemblfungi:YOL105C_mRNA(transcript)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0043332"(mating projection tip)|go:"GO:0071555"(cell wall organization)|interpro:IPR002889(Carbohydrate-binding WSC)|go:"GO:0000324"(fungal-type vacuole)|ensemblfungi:YOL105C(gene)|dip:DIP-1748N|mint:Q12215 refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kddySe6TgeL9Jf6tB4TovTn4T7A559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:6D0DE751FC4C4ADD|rigid:D+Jt/PMjj4edLYwT6qM4s6zkKV4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12215 uniprotkb:Q03640 intact:EBI-20551|uniprotkb:D6W1W1|uniprotkb:Q2VQX5|ensemblfungi:YOL105C intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:wsc3_yeast(display_long)|uniprotkb:WSC3(gene name)|psi-mi:WSC3(display_short)|uniprotkb:HRE556(orf name)|uniprotkb:YOL105C(locus name) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346878|imex:IM-14275-2995 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014536.1|sgd:S000005465|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007266"(Rho protein signal transduction)|ensemblfungi:YOL105C_mRNA(transcript)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0043332"(mating projection tip)|go:"GO:0071555"(cell wall organization)|interpro:IPR002889(Carbohydrate-binding WSC)|go:"GO:0000324"(fungal-type vacuole)|ensemblfungi:YOL105C(gene)|dip:DIP-1748N|mint:Q12215 refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) - crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kddySe6TgeL9Jf6tB4TovTn4T7A559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:FD947A4683C920F0|rigid:WWCgMCvIYAUR/dyiu6DwmqDw/F4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12215 uniprotkb:Q07651 intact:EBI-20551|uniprotkb:D6W1W1|uniprotkb:Q2VQX5|ensemblfungi:YOL105C intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C psi-mi:wsc3_yeast(display_long)|uniprotkb:WSC3(gene name)|psi-mi:WSC3(display_short)|uniprotkb:HRE556(orf name)|uniprotkb:YOL105C(locus name) psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346889|imex:IM-14275-2996 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014536.1|sgd:S000005465|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007266"(Rho protein signal transduction)|ensemblfungi:YOL105C_mRNA(transcript)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0043332"(mating projection tip)|go:"GO:0071555"(cell wall organization)|interpro:IPR002889(Carbohydrate-binding WSC)|go:"GO:0000324"(fungal-type vacuole)|ensemblfungi:YOL105C(gene)|dip:DIP-1748N|mint:Q12215 refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kddySe6TgeL9Jf6tB4TovTn4T7A559292 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 intact-crc:1409B5163A0DD3DF|rigid:3zCHzEt8sy3WIY2FE+llEVW00eQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12220 uniprotkb:P25635 intact:EBI-5896|uniprotkb:Q05386|uniprotkb:D6VYC4|ensemblfungi:YLR129W intact:EBI-14332|uniprotkb:P25633|uniprotkb:P25636|uniprotkb:D6VR63|ensemblfungi:YCR057C psi-mi:utp12_yeast(display_long)|uniprotkb:DIP2(gene name)|psi-mi:DIP2(display_short)|uniprotkb:YLR129W(locus name)|uniprotkb:L9233.1(orf name)|uniprotkb:L3116(orf name)|uniprotkb:UTP12(gene name synonym)|uniprotkb:U three protein 12(gene name synonym)|uniprotkb:DOM34-interacting protein 2(gene name synonym) psi-mi:pwp2_yeast(display_long)|uniprotkb:PWP2(gene name)|psi-mi:PWP2(display_short)|uniprotkb:UTP1(gene name synonym)|uniprotkb:YCR057C(locus name)|uniprotkb:YCR55C/YCR57C/YCR58C(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein 1(gene name synonym)|uniprotkb:U three protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346900|imex:IM-14275-2997 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013230.1|sgd:S000004119|dip:DIP-6494N|mint:Q12220|ensemblfungi:YLR129W(gene)|ensemblfungi:YLR129W_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|go:"GO:0034511"(U3 snoRNA binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR027145|interpro:IPR036322|rcsb pdb:5I2T|rcsb pdb:5WLC|rcsb pdb:5WYJ|ensemblfungi:YCR057C(gene)|ensemblfungi:YCR057C_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:5WYK|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_009984.1|sgd:S000000653|mint:P25635|dip:DIP-1868N psi-mi:"MI:0469"(intact) crc64:7D9AEC7AF6A9C740 crc64:CBEE4720F81378B6 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8Cz4O8hzaHCSq72kVSptQqDE94M559292 rogid:3JKhaE50yPlCymnkEC14JB9atNY559292 intact-crc:B34CB595214E9510|rigid:UiG94S5h3Fggls1RLPE94gSilWU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12220 uniprotkb:P53874 intact:EBI-5896|uniprotkb:Q05386|uniprotkb:D6VYC4|ensemblfungi:YLR129W intact:EBI-19873|uniprotkb:D6W101|ensemblfungi:YNL186W psi-mi:utp12_yeast(display_long)|uniprotkb:DIP2(gene name)|psi-mi:DIP2(display_short)|uniprotkb:YLR129W(locus name)|uniprotkb:L9233.1(orf name)|uniprotkb:L3116(orf name)|uniprotkb:UTP12(gene name synonym)|uniprotkb:U three protein 12(gene name synonym)|uniprotkb:DOM34-interacting protein 2(gene name synonym) psi-mi:ubp10_yeast(display_long)|uniprotkb:UBP10(gene name)|psi-mi:UBP10(display_short)|uniprotkb:YNL186W(locus name)|uniprotkb:N1619(orf name)|uniprotkb:Ubiquitin-specific-processing protease 10(gene name synonym)|uniprotkb:Deubiquitinating enzyme 10(gene name synonym)|uniprotkb:Disrupter of telomere silencing protein 4(gene name synonym)|uniprotkb:Ubiquitin thioesterase 10(gene name synonym)|uniprotkb:DOT4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346911|imex:IM-14275-2998 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013230.1|sgd:S000004119|dip:DIP-6494N|mint:Q12220|ensemblfungi:YLR129W(gene)|ensemblfungi:YLR129W_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|go:"GO:0034511"(U3 snoRNA binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 refseq:NP_014213.2|sgd:S000005130|ensemblfungi:YNL186W(gene)|ensemblfungi:YNL186W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0043596"(nuclear replication fork)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|rcsb pdb:6RR0|dip:DIP-6664N|mint:P53874 psi-mi:"MI:0469"(intact) crc64:7D9AEC7AF6A9C740 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8Cz4O8hzaHCSq72kVSptQqDE94M559292 rogid:Z1rRAI9RLgHeGd7QwLbrf51v5LY559292 intact-crc:4CE7605BA9FC947A|rigid:+QnSWHN08vvrS/bf2vygW2phFXM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12221 uniprotkb:P53829 intact:EBI-37840|uniprotkb:Q02573|uniprotkb:Q04142|uniprotkb:Q7LH42|uniprotkb:Q7LH98|uniprotkb:D6W451|ensemblfungi:YPR042C intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W psi-mi:puf2_yeast(display_long)|uniprotkb:PUF2(gene name)|psi-mi:PUF2(display_short)|uniprotkb:YP3085.06c(orf name)|uniprotkb:YP9499.01(orf name)|uniprotkb:YPR042C(locus name)|uniprotkb:Pumilio homology domain family member 2(gene name synonym) psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346922|imex:IM-14275-2999 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015367.1|sgd:S000006246|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR033133|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:Q12221|ensemblfungi:YPR042C(gene)|ensemblfungi:YPR042C_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 psi-mi:"MI:0469"(intact) - crc64:F3DBABE6AD3C7F3C figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:QV7kn7l+3A4t+8JWJs78oPE/FTg559292 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 intact-crc:BCBAD99E39136E8D|rigid:s84ZRFPwiKuebNhL7u8JBj3e888 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12230 uniprotkb:P19807 intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346933|imex:IM-14275-3000 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) crc64:6FCEE022ECC9778C - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:3862872AD36188A8|rigid:0cxxuHiYf1MyW1B3hiTx74yTRJQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23542 uniprotkb:Q12230 intact:EBI-2002|uniprotkb:D6VY29|ensemblfungi:YLR027C intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C psi-mi:aatc_yeast(display_long)|uniprotkb:AAT2(gene name)|psi-mi:AAT2(display_short)|uniprotkb:YLR027C(locus name)|uniprotkb:ASP5(gene name synonym)|uniprotkb:L1746(orf name)|uniprotkb:Transaminase A(gene name synonym) psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346944|imex:IM-14275-3001 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013127.2|sgd:S000004017|dip:DIP-2897N|mint:P23542|go:"GO:0019266"(asparagine biosynthetic process from oxaloacetate)|go:"GO:0030170"(pyridoxal phosphate binding)|interpro:IPR000796(Aspartate/other aminotransferase)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:1YAA|reactome:R-SCE-70263|reactome:R-SCE-8963693|ensemblfungi:YLR027C(gene)|ensemblfungi:YLR027C_mRNA(transcript)|go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0006532"(aspartate biosynthetic process)|go:"GO:0006536"(glutamate metabolic process) refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT psi-mi:"MI:0469"(intact) crc64:D25F40F6C6DD2B33 crc64:6FCEE022ECC9778C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:eNypS723YWwMMuWVVoTnidvQuaA559292 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 intact-crc:8603CCC72A38184C|rigid:mxm3rZjgGEFrvWK8ngu7kGT7qKY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24276 uniprotkb:Q12230 intact:EBI-18153|uniprotkb:D6VSS2|ensemblfungi:YDR293C intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C psi-mi:ssd1_yeast(display_long)|uniprotkb:SSD1(gene name)|psi-mi:SSD1(display_short)|uniprotkb:CLA1(gene name synonym)|uniprotkb:RLD1(gene name synonym)|uniprotkb:SRK1(gene name synonym)|uniprotkb:YDR293C(locus name)|uniprotkb:D9819.4(orf name)|uniprotkb:Protein SRK1(gene name synonym) psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346955|imex:IM-14275-3002 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010579.1|sgd:S000002701|ensemblfungi:YDR293C(gene)|ensemblfungi:YDR293C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051301"(cell division)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR041093|interpro:IPR041505|rcsb pdb:5NCL|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007049"(cell cycle)|dip:DIP-6449N|mint:P24276 refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT psi-mi:"MI:0469"(intact) crc64:3D50FD6838ECA514 crc64:6FCEE022ECC9778C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:myt8+lnu2/li6TuGiM5GBfMtUiw559292 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 intact-crc:DAD467F2D206DEB2|rigid:mJxhAzLCdfKQ+AONAmyOj44Ad6c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12230 uniprotkb:P25294 intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C intact:EBI-17244|uniprotkb:D6W1H0|ensemblfungi:YNL007C psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:sis1_yeast(display_long)|uniprotkb:YNL007C(locus name)|uniprotkb:SIS1(gene name)|psi-mi:SIS1(display_short)|uniprotkb:N2879(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346966|imex:IM-14275-3003 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT refseq:NP_014391.1|sgd:S000004952|ensemblfungi:YNL007C(gene)|ensemblfungi:YNL007C_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006413"(translational initiation)|go:"GO:0006457"(protein folding)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0035719"(tRNA import into nucleus)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070843"(misfolded protein transport)|go:"GO:0071630"(nuclear protein quality control by the ubiquitin-proteasome system)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|rcsb pdb:1C3G|rcsb pdb:2B26|rcsb pdb:4RWU|rcsb pdb:6D6X|go:"GO:0007049"(cell cycle)|dip:DIP-4385N|mint:P25294 psi-mi:"MI:0469"(intact) crc64:6FCEE022ECC9778C crc64:642D3709C0FD5682 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 rogid:gp39i5OLzpajm1XnD9cYtGKD6kU559292 intact-crc:5D64889A96913318|rigid:woC0CoKT7bGoIjOKIuR/xyMBsto false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:Q12230 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346977|imex:IM-14275-3004 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT psi-mi:"MI:0469"(intact) crc64:8B7F009521F72C15 crc64:6FCEE022ECC9778C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 intact-crc:FFA59E2B5D0CB428|rigid:HSLztR8MzVZKh6cPxvQEOzKL9Zw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12230 uniprotkb:P30605 intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C intact:EBI-2050956|uniprotkb:D6VTB9|ensemblfungi:YDR497C psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:itr1_yeast(display_long)|uniprotkb:D9719.3(orf name)|uniprotkb:YDR497C(locus name)|uniprotkb:ITR1(gene name)|psi-mi:ITR1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346988|imex:IM-14275-3005 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT refseq:NP_010785.1|sgd:S000002905|dip:DIP-7406N|mint:P30605|ensemblfungi:YDR497C(gene)|ensemblfungi:YDR497C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:6FCEE022ECC9778C - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 rogid:GgtK4YFe7ZCZcmVpV5q1KY2F0Ds559292 intact-crc:4608A0946BACFDAA|rigid:nKpIqMTEMaV+ymuIkder/PViLXA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12230 uniprotkb:P32324 intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C intact:EBI-6333|uniprotkb:Q6JEF7|uniprotkb:D6VT19|ensemblfungi:YDR385W|ensemblfungi:YOR133W psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:ef2_yeast(display_long)|uniprotkb:EFT1(gene name)|psi-mi:EFT1(display_short)|uniprotkb:YOR133W(locus name)|uniprotkb:O3317(orf name)|uniprotkb:YOR3317W(orf name)|uniprotkb:EFT2(gene name)|psi-mi:EFT2(display_short)|uniprotkb:YDR385W(locus name)|uniprotkb:Translation elongation factor 2(gene name synonym)|uniprotkb:Eukaryotic elongation factor 2(gene name synonym)|uniprotkb:Ribosomal translocase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6346999|imex:IM-14275-3006 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT refseq:NP_010673.1|refseq:NP_014776.1|sgd:S000005659|sgd:S000002793|ensemblfungi:YDR385W(gene)|ensemblfungi:YDR385W_mRNA(transcript)|ensemblfungi:YOR133W(gene)|ensemblfungi:YOR133W_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0019843"(rRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0051087"(chaperone binding)|go:"GO:1990145"(maintenance of translational fidelity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|mint:P32324|dip:DIP-4911N|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|rcsb pdb:1N0U|rcsb pdb:1N0V|rcsb pdb:1U2R|rcsb pdb:1ZM2|rcsb pdb:1ZM3|rcsb pdb:1ZM4|rcsb pdb:1ZM9|rcsb pdb:2E1R|rcsb pdb:2NPF|rcsb pdb:2P8W|rcsb pdb:2P8X|rcsb pdb:2P8Y|rcsb pdb:2P8Z|rcsb pdb:2ZIT|rcsb pdb:3B78|rcsb pdb:3B82|rcsb pdb:3B8H|rcsb pdb:3DNY|rcsb pdb:4V4B|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|reactome:R-SCE-156902|reactome:R-SCE-5358493|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) crc64:6FCEE022ECC9778C crc64:FD2F8073CB9B66AA figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 rogid:mlyt9YKZrGhGbsSlvxNJ0p1C67I559292 intact-crc:97659B52DFB9D73D|rigid:tk7k0dVlRJYuOQPVRIwQCRxEgHs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12230 uniprotkb:P32590 intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C intact:EBI-8655|uniprotkb:D6VQG5|ensemblfungi:YBR169C psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:hsp79_yeast(display_long)|uniprotkb:SSE2(gene name)|psi-mi:SSE2(display_short)|uniprotkb:HSP(gene name synonym)|uniprotkb:YBR169C(locus name)|uniprotkb:YBR1221(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347010|imex:IM-14275-3007 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT refseq:NP_009728.1|sgd:S000000373|mint:P32590|dip:DIP-4862N|ensemblfungi:YBR169C(gene)|ensemblfungi:YBR169C_mRNA(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0042026"(protein refolding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129 psi-mi:"MI:0469"(intact) crc64:6FCEE022ECC9778C crc64:D6BC9656D93895C2 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 rogid:OugvlU8M3Sa7gMKDffVZ0V2/jpg559292 intact-crc:4FADDD4002687F4A|rigid:obzyc1yeJZEuws9qEesDfx72qoo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12230 uniprotkb:P36027 intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347021|imex:IM-14275-3008 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) crc64:6FCEE022ECC9778C - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:F0AF85DB183EAA84|rigid:un0ts1etI8TEOYJZCoBJFDChhH8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12230 uniprotkb:P38328 intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347032|imex:IM-14275-3009 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:6FCEE022ECC9778C crc64:D75C6BB8EC35EEDF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 intact-crc:BF6F3EAFC19358B4|rigid:2MSEKFk9xYdZy6aGjA4/W4QsVTQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39976 uniprotkb:Q12230 intact:EBI-5933|uniprotkb:D3DLI0|ensemblfungi:YEL071W intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C psi-mi:dld3_yeast(display_long)|uniprotkb:YEL071W(locus name)|uniprotkb:DLD3(gene name)|psi-mi:DLD3(display_short)|uniprotkb:D-lactate ferricytochrome C oxidoreductase(gene name synonym)|uniprotkb:"(R)-2-hydroxyglutarate--pyruvate transhydrogenase"(gene name synonym)|uniprotkb:D-lactate dehydrogenase [cytochrome] 3(gene name synonym) psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347043|imex:IM-14275-3010 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010843.1|sgd:S000000797|dip:DIP-6418N|mint:P39976|ensemblfungi:YEL071W(gene)|ensemblfungi:YEL071W_mRNA(transcript)|go:"GO:0004458"("D-lactate dehydrogenase (cytochrome) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0030447"(filamentous growth)|go:"GO:0071949"(FAD binding)|go:"GO:0099615"("(D)-2-hydroxyglutarate-pyruvate transhydrogenase activity")|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)|interpro:IPR036318 refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT psi-mi:"MI:0469"(intact) crc64:4809F74EDF07F520 crc64:6FCEE022ECC9778C figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:f0zrUtFfKHDu2gUN7thcyPp/Z50559292 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 intact-crc:04D11BF0B29EC153|rigid:d85onGf2CvDTbqXE7NrIFf+Moy8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40023 uniprotkb:Q12230 intact:EBI-22493|uniprotkb:D3DLT4|ensemblfungi:YER035W intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C psi-mi:edc2_yeast(display_long)|uniprotkb:YER035W(locus name)|uniprotkb:EDC2(gene name)|psi-mi:EDC2(display_short) psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347054|imex:IM-14275-3011 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000837|refseq:NP_010952.3|dip:DIP-5234N|mint:P40023|ensemblfungi:YER035W(gene)|ensemblfungi:YER035W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0032056"(positive regulation of translation in response to stress) refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT psi-mi:"MI:0469"(intact) crc64:4D8A461EFD78BFA9 crc64:6FCEE022ECC9778C figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nW5oKJQ2vCy2/EmFSke5vZAK/3U559292 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 intact-crc:C6981E03CB68D01C|rigid:3a9DpuWRbgt6Vuc4mmjmQh6CyJU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41811 uniprotkb:Q12230 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347065|imex:IM-14275-3012 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT psi-mi:"MI:0469"(intact) crc64:6A5E50BBEB02CB58 crc64:6FCEE022ECC9778C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 intact-crc:8FBEF96BBDC98541|rigid:NYPWVRJFdVG6REY5n2l8+LWuQ2s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47039 uniprotkb:Q12230 intact:EBI-25893|uniprotkb:D6VWC2|ensemblfungi:YJL060W intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C psi-mi:bna3_yeast(display_long)|uniprotkb:YJL060W(locus name)|uniprotkb:J1138(orf name)|uniprotkb:Biosynthesis of nicotinic acid protein 3(gene name synonym)|uniprotkb:BNA3(gene name)|psi-mi:BNA3(display_short)|uniprotkb:Kynurenine aminotransferase(gene name synonym) psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347076|imex:IM-14275-3013 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003596|refseq:NP_012475.3|mint:P47039|dip:DIP-6723N|ensemblfungi:YJL060W(gene)|ensemblfungi:YJL060W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0016212"(kynurenine-oxoglutarate transaminase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034276"(kynurenic acid biosynthetic process)|go:"GO:0047536"(2-aminoadipate transaminase activity)|go:"GO:0097053"(L-kynurenine catabolic process)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:3B46|reactome:R-SCE-71240|reactome:R-SCE-8964208|reactome:R-SCE-8964539 refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT psi-mi:"MI:0469"(intact) - crc64:6FCEE022ECC9778C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Fli6ip0tteNbMkQG9h7/IBow3ms559292 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 intact-crc:F20192085F5A4422|rigid:9rMiREZDgP55gZZVSIbxu1z4npw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:Q12230 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347087|imex:IM-14275-3014 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT psi-mi:"MI:0469"(intact) - crc64:6FCEE022ECC9778C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 intact-crc:731E22FAF506CC58|rigid:iGdkfnK4X5Zqf17jrgmXrX8XMy8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53235 uniprotkb:Q12230 intact:EBI-23172|uniprotkb:D6VUI9|uniprotkb:Q45U32|ensemblfungi:YGR054W intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C psi-mi:eif2a_yeast(display_long)|uniprotkb:YGR054W(locus name) psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347098|imex:IM-14275-3015 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003286|refseq:NP_011568.3|dip:DIP-5518N|mint:P53235|ensemblfungi:YGR054W(gene)|ensemblfungi:YGR054W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like) refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT psi-mi:"MI:0469"(intact) crc64:F3C2E78504D83418 crc64:6FCEE022ECC9778C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:x8zDCH5W5GusC7qYd0mDATXhGVI559292 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 intact-crc:AB99135420798F38|rigid:Jmd4R5capkm6fHrPtubE13cWAX8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53278 uniprotkb:Q12230 intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name) psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347109|imex:IM-14275-3016 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome) refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT psi-mi:"MI:0469"(intact) crc64:D482327C9274C026 crc64:6FCEE022ECC9778C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 intact-crc:AB1D136791DF5203|rigid:woXXWlZf7Y1UGYPulZhYqYCWDok false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53731 uniprotkb:Q12230 intact:EBI-2770|uniprotkb:D6W1L1|ensemblfungi:YNR035C intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C psi-mi:arpc2_yeast(display_long)|uniprotkb:ARC35(gene name)|psi-mi:ARC35(display_short)|uniprotkb:YNR035C(locus name)|uniprotkb:N3296(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym) psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347120|imex:IM-14275-3017 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014433.1|sgd:S000005318|dip:DIP-2304N|mint:P53731|ensemblfungi:YNR035C(gene)|ensemblfungi:YNR035C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072697"(protein localization to cell cortex)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT psi-mi:"MI:0469"(intact) crc64:9AF71A93688729F6 crc64:6FCEE022ECC9778C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:URdgP2srz1O44fNGQh18L7bzC+c559292 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 intact-crc:3ACBF646D589A6AF|rigid:Q2+Cki8tOeePxqgtOBB2A5ZjC9E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12230 uniprotkb:P54113 intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C intact:EBI-14213|uniprotkb:E9PAG6|ensemblfungi:YLR028C|uniprotkb:D6VY30 psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:pur91_yeast(display_long)|uniprotkb:ADE16(gene name)|psi-mi:ADE16(display_short)|uniprotkb:YLR028C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347131|imex:IM-14275-3018 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT mint:P54113|refseq:NP_013128.1|sgd:S000004018|ensemblfungi:YLR028C(gene)|ensemblfungi:YLR028C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|interpro:IPR036914|dip:DIP-4657N psi-mi:"MI:0469"(intact) crc64:6FCEE022ECC9778C - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 rogid:SbZvY+c2tg098pE/sezKQp+3cFE559292 intact-crc:C1923C68A61BF53C|rigid:Y6oc3FLLL8TEy6rIOAQ5aDoGdXQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54783 uniprotkb:Q12230 intact:EBI-2519|uniprotkb:O42618|ensemblfungi:YML086C|uniprotkb:D6W0J7 intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C psi-mi:alo_yeast(display_long)|uniprotkb:ALO1(gene name)|psi-mi:ALO1(display_short)|uniprotkb:L-galactono-gamma-lactone oxidase(gene name synonym)|uniprotkb:YML086C(locus name) psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347142|imex:IM-14275-3019 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070485"(dehydro-D-arabinono-1,4-lactone biosynthetic process)|go:"GO:0071949"(FAD binding)|ensemblfungi:YML086C(gene)|ensemblfungi:YML086C_mRNA(transcript)|go:"GO:0003885"(D-arabinono-1,4-lactone oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_013624.1|sgd:S000004551|interpro:IPR007173(D-arabinono-1,4-lactone oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR010031(Sugar 1,4-lactone oxidases)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR006093(Oxygen oxidoreductase covalent FAD-binding site)|interpro:IPR030654|mint:P54783|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT psi-mi:"MI:0469"(intact) - crc64:6FCEE022ECC9778C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:58c11VZCSt9MMF7gja5BQjbFXIk559292 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 intact-crc:C3987A688756CF73|rigid:Q0lIx8M2DHm+HmxptirEPaDB50w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06170 uniprotkb:Q12230 intact:EBI-35994|uniprotkb:D6VYW8|ensemblfungi:YLR326W intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C psi-mi:yl326_yeast(display_long)|uniprotkb:YLR326W(locus name) psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347153|imex:IM-14275-3020 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013430.1|sgd:S000004318|mint:Q06170|dip:DIP-3995N|ensemblfungi:YLR326W(gene)|ensemblfungi:YLR326W_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR025187 refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT psi-mi:"MI:0469"(intact) crc64:724CD7833AA9B416 crc64:6FCEE022ECC9778C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ufkoj1kRp4Y9JTsgbL+3k8hzJyo559292 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 intact-crc:ED5C5A0B707F41C7|rigid:bKxYd/4035t0heCe6wDKi+fC6ls false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08967 uniprotkb:Q12230 intact:EBI-36673|uniprotkb:D6W3E9|ensemblfungi:YPL221W intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C psi-mi:flc1_yeast(display_long)|uniprotkb:FAD transporter 1(gene name synonym)|uniprotkb:FLC1(gene name)|psi-mi:FLC1(display_short)|uniprotkb:TRP-like ion channel protein FLC1(gene name synonym)|uniprotkb:Heme utilization factor 1(gene name synonym)|uniprotkb:Bypass of PAM1 protein 1(gene name synonym)|uniprotkb:HUF1(gene name synonym)|uniprotkb:YPL221W(locus name)|uniprotkb:BOP1(gene name synonym) psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347164|imex:IM-14275-3021 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015103.1|sgd:S000006142|mint:Q08967|dip:DIP-3965N|ensemblfungi:YPL221W(gene)|ensemblfungi:YPL221W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055085"(transmembrane transport)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241 refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT psi-mi:"MI:0469"(intact) - crc64:6FCEE022ECC9778C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:r6CcZGEjxHUk2w0iBUBvnAPaFd4559292 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 intact-crc:91B74A5A468B2439|rigid:K/Z+vgEPKHk6C3esRrfiSff56Qs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12230 uniprotkb:Q12256 intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347175|imex:IM-14275-3022 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:6FCEE022ECC9778C - figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 intact-crc:4C39ECB614BFBA6C|rigid:30KAcOorXZsF+tlBl/entDG+ex0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12230 uniprotkb:Q3E772 intact:EBI-34978|uniprotkb:D6W408|ensemblfungi:YPL004C intact:EBI-2070524|uniprotkb:D6VUV3|ensemblfungi:YGR169C-A psi-mi:lsp1_yeast(display_long)|uniprotkb:LSP1(gene name)|psi-mi:LSP1(display_short)|uniprotkb:YPL004C(locus name) psi-mi:lso2_yeast(display_long)|uniprotkb:LSO2(gene name)|psi-mi:LSO2(display_short)|uniprotkb:Late-annotated small open reading frame 2(gene name synonym)|uniprotkb:YGR169C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347186|imex:IM-14275-3023 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015321.1|sgd:S000005925|mint:Q12230|dip:DIP-3993N|ensemblfungi:YPL004C(gene)|ensemblfungi:YPL004C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR027267|interpro:IPR028245|rcsb pdb:3PLT sgd:S000028521|refseq:NP_878080.3|mint:Q3E772|ensemblfungi:YGR169C-A(gene)|ensemblfungi:YGR169C-A_mRNA(transcript)|go:"GO:0002182"(cytoplasmic translational elongation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0043022"(ribosome binding)|go:"GO:0055072"(iron ion homeostasis)|rcsb pdb:6Z6J|rcsb pdb:6Z6K psi-mi:"MI:0469"(intact) crc64:6FCEE022ECC9778C - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ftVJicoyXctwySSqddpuRNMuxJI559292 rogid:rgtvxbeFiShVE//UX0Py5Rw3BmU559292 intact-crc:9BB4194CAB139631|rigid:EIEwCcEHWC1IBzoy3ughEc+ziFk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12250 uniprotkb:P43588 intact:EBI-15935|uniprotkb:D6VRK1|ensemblfungi:YDL147W intact:EBI-11219|uniprotkb:Q8J0T5|uniprotkb:D6VTN4|ensemblfungi:YFR004W psi-mi:rpn5_yeast(display_long)|uniprotkb:RPN5(gene name)|psi-mi:RPN5(display_short)|uniprotkb:NAS5(gene name synonym)|uniprotkb:YDL147W(locus name)|uniprotkb:D1572(orf name)|uniprotkb:Proteasome non-ATPase subunit 5(gene name synonym) psi-mi:rpn11_yeast(display_long)|uniprotkb:YFR004W(locus name)|uniprotkb:RPN11(gene name)|psi-mi:RPN11(display_short)|uniprotkb:MPR1(gene name synonym)|uniprotkb:Protein MPR1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN11(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347197|imex:IM-14275-3024 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010134.1|sgd:S000002306|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035297|interpro:IPR036388|interpro:IPR036390|interpro:IPR040134|interpro:IPR040896|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:5ZMR|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:6FVX|ensemblfungi:YDL147W(gene)|ensemblfungi:YDL147W_mRNA(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0000502"(proteasome complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0034515"(proteasome storage granule)|rcsb pdb:6J2C|rcsb pdb:6FVY|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|dip:DIP-1578N|mint:Q12250 ensemblfungi:YFR004W(gene)|ensemblfungi:YFR004W_mRNA(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016559"(peroxisome fission)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070628"(proteasome binding)|go:"GO:1902906"(proteasome storage granule assembly)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4O8X|rcsb pdb:4O8Y|rcsb pdb:4OCL|rcsb pdb:4OCM|go:"GO:0070122"(isopeptidase activity)|rcsb pdb:4OCN|rcsb pdb:4OWP|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5U4P|rcsb pdb:5W83|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-5689901|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|refseq:NP_116659.1|sgd:S000001900|mint:P43588|dip:DIP-1573N psi-mi:"MI:0469"(intact) crc64:E5DC7F8E6AE27736 crc64:9DDE8BD74890894D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:DaeRxapE6TgoZG4emWRb3y12Vfc559292 rogid:f3lAMY9siMcO2dAOfKvVrvKzfNM559292 intact-crc:DCC25CB21EC5F9A5|rigid:Ed47xifm4qhrkEv3WaovEAIRcR4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04062 uniprotkb:Q12250 intact:EBI-15944|uniprotkb:D6VT56|ensemblfungi:YDR427W intact:EBI-15935|uniprotkb:D6VRK1|ensemblfungi:YDL147W psi-mi:rpn9_yeast(display_long)|uniprotkb:RPN9(gene name)|psi-mi:RPN9(display_short)|uniprotkb:NAS7(gene name synonym)|uniprotkb:YDR427W(locus name)|uniprotkb:D9461.14(orf name)|uniprotkb:Proteasome non-ATPase subunit 7(gene name synonym) psi-mi:rpn5_yeast(display_long)|uniprotkb:RPN5(gene name)|psi-mi:RPN5(display_short)|uniprotkb:NAS5(gene name synonym)|uniprotkb:YDL147W(locus name)|uniprotkb:D1572(orf name)|uniprotkb:Proteasome non-ATPase subunit 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347208|imex:IM-14275-3025 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002835|ensemblfungi:YDR427W(gene)|ensemblfungi:YDR427W_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043248"(proteasome assembly)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035298|interpro:IPR036390|interpro:IPR040798|rcsb pdb:2MQW|rcsb pdb:2MR3|rcsb pdb:2MRI|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|refseq:NP_010715.3|dip:DIP-5261N|mint:Q04062 refseq:NP_010134.1|sgd:S000002306|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035297|interpro:IPR036388|interpro:IPR036390|interpro:IPR040134|interpro:IPR040896|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:5ZMR|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:6FVX|ensemblfungi:YDL147W(gene)|ensemblfungi:YDL147W_mRNA(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0000502"(proteasome complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0034515"(proteasome storage granule)|rcsb pdb:6J2C|rcsb pdb:6FVY|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|dip:DIP-1578N|mint:Q12250 psi-mi:"MI:0469"(intact) crc64:540F7DF8C23469A1 crc64:E5DC7F8E6AE27736 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hOAU0IY1VeRlmtX4Dw3MNJybZaE559292 rogid:DaeRxapE6TgoZG4emWRb3y12Vfc559292 intact-crc:42EE73FADAE9851D|rigid:EjYVXPbV9ECXY098pzkkSEw1Y2Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08723 uniprotkb:Q12250 intact:EBI-36176|uniprotkb:Q6Q5I7|uniprotkb:D6W2W2|ensemblfungi:YOR261C intact:EBI-15935|uniprotkb:D6VRK1|ensemblfungi:YDL147W psi-mi:rpn8_yeast(display_long)|uniprotkb:RPN8(gene name)|psi-mi:RPN8(display_short)|uniprotkb:O5360(orf name)|uniprotkb:YOR261C(locus name) psi-mi:rpn5_yeast(display_long)|uniprotkb:RPN5(gene name)|psi-mi:RPN5(display_short)|uniprotkb:NAS5(gene name synonym)|uniprotkb:YDL147W(locus name)|uniprotkb:D1572(orf name)|uniprotkb:Proteasome non-ATPase subunit 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347219|imex:IM-14275-3026 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005787|refseq:NP_014904.3|mint:Q08723|dip:DIP-1574N|ensemblfungi:YOR261C(gene)|ensemblfungi:YOR261C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4O8X|rcsb pdb:4O8Y|rcsb pdb:4OCL|rcsb pdb:4OCM|rcsb pdb:4OCN|rcsb pdb:4OWP|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5U4P|rcsb pdb:5W83|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168 refseq:NP_010134.1|sgd:S000002306|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035297|interpro:IPR036388|interpro:IPR036390|interpro:IPR040134|interpro:IPR040896|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:5ZMR|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:6FVX|ensemblfungi:YDL147W(gene)|ensemblfungi:YDL147W_mRNA(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0000502"(proteasome complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0034515"(proteasome storage granule)|rcsb pdb:6J2C|rcsb pdb:6FVY|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|dip:DIP-1578N|mint:Q12250 psi-mi:"MI:0469"(intact) crc64:6EE6009545A3D0EF crc64:E5DC7F8E6AE27736 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kvJ/LyyQGKi5JTh4Fek1kh70jOU559292 rogid:DaeRxapE6TgoZG4emWRb3y12Vfc559292 intact-crc:CEEA9272757AFE4C|rigid:5S1prQ4V8GHdcL8HKGUkEMF9n/4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12250 uniprotkb:Q12377 intact:EBI-15935|uniprotkb:D6VRK1|ensemblfungi:YDL147W intact:EBI-308|uniprotkb:D6VRQ3|ensemblfungi:YDL097C psi-mi:rpn5_yeast(display_long)|uniprotkb:RPN5(gene name)|psi-mi:RPN5(display_short)|uniprotkb:NAS5(gene name synonym)|uniprotkb:YDL147W(locus name)|uniprotkb:D1572(orf name)|uniprotkb:Proteasome non-ATPase subunit 5(gene name synonym) psi-mi:rpn6_yeast(display_long)|uniprotkb:RPN6(gene name)|psi-mi:RPN6(display_short)|uniprotkb:NAS4(gene name synonym)|uniprotkb:YDL097C(locus name)|uniprotkb:D2381(orf name)|uniprotkb:Proteasome non-ATPase subunit 4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347230|imex:IM-14275-3027 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010134.1|sgd:S000002306|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035297|interpro:IPR036388|interpro:IPR036390|interpro:IPR040134|interpro:IPR040896|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:5ZMR|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:6FVX|ensemblfungi:YDL147W(gene)|ensemblfungi:YDL147W_mRNA(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0000502"(proteasome complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0034515"(proteasome storage granule)|rcsb pdb:6J2C|rcsb pdb:6FVY|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|dip:DIP-1578N|mint:Q12250 refseq:NP_010186.1|sgd:S000002255|dip:DIP-1581N|mint:Q12377|ensemblfungi:YDL097C(gene)|ensemblfungi:YDL097C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043248"(proteasome assembly)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR036390|interpro:IPR040773|interpro:IPR040780|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168 psi-mi:"MI:0469"(intact) crc64:E5DC7F8E6AE27736 crc64:A8B1F7E6F73A4024 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:DaeRxapE6TgoZG4emWRb3y12Vfc559292 rogid:Q7d0N0C4nR9dUZHh+zofzWAF/t8559292 intact-crc:9D28CA3F6C193C21|rigid:eVCUTRnV5Gq+7rxYww6ii+qcjsI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12256 uniprotkb:P10823 intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347241|imex:IM-14275-3028 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0469"(intact) - crc64:881B91792AE91748 figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 intact-crc:A6FAACDF2718C7F9|rigid:62uof8VOC8J/ayzKDcJKNwch+TA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12256 uniprotkb:P19807 intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347252|imex:IM-14275-3029 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 intact-crc:8E352BC4DB847497|rigid:/R9O7w+xvV8mPgZdxvNkCUYmypY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12256 uniprotkb:P25619 intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347263|imex:IM-14275-3030 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476 psi-mi:"MI:0469"(intact) - crc64:260474A481D29AC5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292 intact-crc:A686A04718DECD59|rigid:MsE3ZYecMYfL1IswYLHTn3alQH4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12256 uniprotkb:P35735 intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347274|imex:IM-14275-3031 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:45163D4F6E8A200C|rigid:bZlI3dBgI1qCxpPhP90B0GQmQWo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12256 uniprotkb:P36027 intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347285|imex:IM-14275-3032 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:46F8293510DB56BB|rigid:Ygf5W4QeC/JubE4DX8og8Mn1i+A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53049 uniprotkb:Q12256 intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347296|imex:IM-14275-3033 author score:85.04 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:85.04|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 intact-crc:8031BD8D22CC7625|rigid:jvJVCU7iHOZ0O8oz7zNv3rBTVgw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53278 uniprotkb:Q12256 intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name) psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347307|imex:IM-14275-3034 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome) refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 psi-mi:"MI:0469"(intact) crc64:D482327C9274C026 - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 intact-crc:1D4ABA29911AAE3C|rigid:A9TwDpeSfo0vKc4uRRcCixEJTyE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12256 uniprotkb:Q02201 intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C intact:EBI-12636|uniprotkb:D6VXT9|ensemblfungi:YKR003W psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:osh6_yeast(display_long)|uniprotkb:YK102(orf name)|uniprotkb:YKR003W(locus name)|uniprotkb:OSH6(gene name)|psi-mi:OSH6(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347318|imex:IM-14275-3035 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0015914"(phospholipid transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0120015"(sterol transfer activity)|rcsb pdb:4B2Z|rcsb pdb:4PH7|reactome:R-SCE-1482801|reactome:R-SCE-192105|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensemblfungi:YKR003W(gene)|ensemblfungi:YKR003W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|refseq:NP_012928.1|sgd:S000001711|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|mint:Q02201 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 rogid:aOZdSdLn96ns0C9w9E3r62iNyYo559292 intact-crc:82E6EDC5D2FC9C0C|rigid:2ZumC9Z8119zxO9FmcL36fm9OM0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12256 uniprotkb:Q02785 intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347329|imex:IM-14275-3036 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:08BC0D770AC77959|rigid:Q3vNcgQu9/3mcb3h7pIi5hgvQt4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12256 uniprotkb:Q03640 intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347340|imex:IM-14275-3037 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) - crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:982C006075421374|rigid:vq47VD8t486RE7poWKiPBCJcktk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08967 uniprotkb:Q12256 intact:EBI-36673|uniprotkb:D6W3E9|ensemblfungi:YPL221W intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C psi-mi:flc1_yeast(display_long)|uniprotkb:FAD transporter 1(gene name synonym)|uniprotkb:FLC1(gene name)|psi-mi:FLC1(display_short)|uniprotkb:TRP-like ion channel protein FLC1(gene name synonym)|uniprotkb:Heme utilization factor 1(gene name synonym)|uniprotkb:Bypass of PAM1 protein 1(gene name synonym)|uniprotkb:HUF1(gene name synonym)|uniprotkb:YPL221W(locus name)|uniprotkb:BOP1(gene name synonym) psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347351|imex:IM-14275-3038 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015103.1|sgd:S000006142|mint:Q08967|dip:DIP-3965N|ensemblfungi:YPL221W(gene)|ensemblfungi:YPL221W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055085"(transmembrane transport)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241 refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:r6CcZGEjxHUk2w0iBUBvnAPaFd4559292 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 intact-crc:27E0E6B44E6ED806|rigid:RL0NHbVgvRfs72bXvn9O2Zrilus false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12256 uniprotkb:Q12335 intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347362|imex:IM-14275-3039 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) - crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:6126EC5431C3007D|rigid:/Ugdsv/PwBZiXlLalHTfSuDE13M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25293 uniprotkb:Q12263 intact:EBI-11850|uniprotkb:P87196|ensemblfungi:YKR048C|uniprotkb:D6VXA9 intact:EBI-7595|uniprotkb:D6VTC9|ensemblfungi:YDR507C psi-mi:nap1_yeast(display_long)|uniprotkb:NAP1(gene name)|psi-mi:NAP1(display_short)|uniprotkb:YKR048C(locus name) psi-mi:gin4_yeast(display_long)|uniprotkb:GIN4(gene name)|psi-mi:GIN4(display_short)|uniprotkb:YDR507C(locus name)|uniprotkb:D9719.13(orf name)|uniprotkb:Growth inhibitory protein 4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347373|imex:IM-14275-3040 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YKR048C(gene)|ensemblfungi:YKR048C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032153"(cell division site)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0098841"(protein localization to cell division site after cytokinesis)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|rcsb pdb:2AYU|rcsb pdb:2Z2R|rcsb pdb:5G2E|go:"GO:0032174"(cellular bud neck septin collar)|refseq:NP_012974.1|sgd:S000001756|dip:DIP-1380N|mint:P25293 sgd:S000002915|refseq:NP_010795.3|mint:Q12263|dip:DIP-2260N|ensemblfungi:YDR507C(gene)|ensemblfungi:YDR507C_mRNA(transcript)|go:"GO:0000921"(septin ring assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044879"(mitotic morphogenesis checkpoint signaling)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901900"(regulation of protein localization to cell division site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR031850|interpro:IPR043024 psi-mi:"MI:0469"(intact) crc64:C0F97FBA1B9EEA83 crc64:EC16FF4BB49DD811 figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:MBxVJ0JmlEg5coqnQd6uoSX2uC0559292 rogid:UNOrpwVYa+uRG+zarmfFgRBsRxc559292 intact-crc:4E89BBA874533D0C|rigid:WwPlGU95WbBooMyeE9gA9xhPeAA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12263 uniprotkb:P36027 intact:EBI-7595|uniprotkb:D6VTC9|ensemblfungi:YDR507C intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:gin4_yeast(display_long)|uniprotkb:GIN4(gene name)|psi-mi:GIN4(display_short)|uniprotkb:YDR507C(locus name)|uniprotkb:D9719.13(orf name)|uniprotkb:Growth inhibitory protein 4(gene name synonym) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347384|imex:IM-14275-3041 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002915|refseq:NP_010795.3|mint:Q12263|dip:DIP-2260N|ensemblfungi:YDR507C(gene)|ensemblfungi:YDR507C_mRNA(transcript)|go:"GO:0000921"(septin ring assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044879"(mitotic morphogenesis checkpoint signaling)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901900"(regulation of protein localization to cell division site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR031850|interpro:IPR043024 ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) crc64:EC16FF4BB49DD811 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UNOrpwVYa+uRG+zarmfFgRBsRxc559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:E445C596C8906D5E|rigid:bby/UhTg5YuZylAk4Y1UNoAfDGM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12263 uniprotkb:Q02785 intact:EBI-7595|uniprotkb:D6VTC9|ensemblfungi:YDR507C intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:gin4_yeast(display_long)|uniprotkb:GIN4(gene name)|psi-mi:GIN4(display_short)|uniprotkb:YDR507C(locus name)|uniprotkb:D9719.13(orf name)|uniprotkb:Growth inhibitory protein 4(gene name synonym) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347395|imex:IM-14275-3042 author score:99.36 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002915|refseq:NP_010795.3|mint:Q12263|dip:DIP-2260N|ensemblfungi:YDR507C(gene)|ensemblfungi:YDR507C_mRNA(transcript)|go:"GO:0000921"(septin ring assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044879"(mitotic morphogenesis checkpoint signaling)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901900"(regulation of protein localization to cell division site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR031850|interpro:IPR043024 refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) crc64:EC16FF4BB49DD811 - figure legend:tables S3 and S4|author-confidence:99.36|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UNOrpwVYa+uRG+zarmfFgRBsRxc559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:AA044304D28C42BC|rigid:OHM7P2TO5BmSW4kUkPcQ/O1DdFM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32895 uniprotkb:Q12265 intact:EBI-9869|uniprotkb:D6VX20|ensemblfungi:YKL181W intact:EBI-9886|ensemblfungi:YOL061W|uniprotkb:D6W206 psi-mi:kpr1_yeast(display_long)|uniprotkb:PPS1(gene name synonym)|uniprotkb:PRP1(gene name synonym)|uniprotkb:PRPS(gene name synonym)|uniprotkb:PRPS1(gene name synonym)|uniprotkb:YKL181W(locus name)|uniprotkb:PRS1(gene name)|psi-mi:PRS1(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 1(gene name synonym) psi-mi:kpr5_yeast(display_long)|uniprotkb:PRS5(gene name)|psi-mi:PRS5(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 5(gene name synonym)|uniprotkb:PRPS5(gene name synonym)|uniprotkb:O1213(orf name)|uniprotkb:YOL061W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347406|imex:IM-14275-3043 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012740.1|sgd:S000001664|ensemblfungi:YKL181W(gene)|ensemblfungi:YKL181W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|dip:DIP-4857N|mint:P32895 refseq:NP_014580.1|sgd:S000005422|ensemblfungi:YOL061W(gene)|ensemblfungi:YOL061W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|dip:DIP-1532N|mint:Q12265 psi-mi:"MI:0469"(intact) crc64:F3E93ACB25E703FF crc64:75C948D40D58256D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ea45pOje4sjYrrU7ze4Af443yDk559292 rogid:vnGVKU7vl2NG7lgcrlTVSHYYQMI559292 intact-crc:5DF84ACF46532773|rigid:E6ZDydGcmO1F3IkDRGTJCJpw/58 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38689 uniprotkb:Q12265 intact:EBI-9877|uniprotkb:D3DKQ2|ensemblfungi:YHL011C intact:EBI-9886|ensemblfungi:YOL061W|uniprotkb:D6W206 psi-mi:kpr3_yeast(display_long)|uniprotkb:PRS3(gene name)|psi-mi:PRS3(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 3(gene name synonym)|uniprotkb:PRPS3(gene name synonym)|uniprotkb:YHL011C(locus name) psi-mi:kpr5_yeast(display_long)|uniprotkb:PRS5(gene name)|psi-mi:PRS5(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 5(gene name synonym)|uniprotkb:PRPS5(gene name synonym)|uniprotkb:O1213(orf name)|uniprotkb:YOL061W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347417|imex:IM-14275-3044 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011852.1|sgd:S000001003|ensemblfungi:YHL011C(gene)|ensemblfungi:YHL011C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|dip:DIP-4307N|mint:P38689 refseq:NP_014580.1|sgd:S000005422|ensemblfungi:YOL061W(gene)|ensemblfungi:YOL061W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|dip:DIP-1532N|mint:Q12265 psi-mi:"MI:0469"(intact) crc64:D4839D217B7513C4 crc64:75C948D40D58256D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8Km+h9PM9lJSTwLUTObbTkNkKig559292 rogid:vnGVKU7vl2NG7lgcrlTVSHYYQMI559292 intact-crc:DB8BA1325CFAB5BB|rigid:DRxtbWySbkHFtWdZvv6tg3SxW6k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12265 uniprotkb:Q12265 intact:EBI-9886|ensemblfungi:YOL061W|uniprotkb:D6W206 intact:EBI-9886|ensemblfungi:YOL061W|uniprotkb:D6W206 psi-mi:kpr5_yeast(display_long)|uniprotkb:PRS5(gene name)|psi-mi:PRS5(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 5(gene name synonym)|uniprotkb:PRPS5(gene name synonym)|uniprotkb:O1213(orf name)|uniprotkb:YOL061W(locus name) psi-mi:kpr5_yeast(display_long)|uniprotkb:PRS5(gene name)|psi-mi:PRS5(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 5(gene name synonym)|uniprotkb:PRPS5(gene name synonym)|uniprotkb:O1213(orf name)|uniprotkb:YOL061W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347428|imex:IM-14275-3045 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014580.1|sgd:S000005422|ensemblfungi:YOL061W(gene)|ensemblfungi:YOL061W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|dip:DIP-1532N|mint:Q12265 refseq:NP_014580.1|sgd:S000005422|ensemblfungi:YOL061W(gene)|ensemblfungi:YOL061W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|dip:DIP-1532N|mint:Q12265 psi-mi:"MI:0469"(intact) crc64:75C948D40D58256D crc64:75C948D40D58256D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vnGVKU7vl2NG7lgcrlTVSHYYQMI559292 rogid:vnGVKU7vl2NG7lgcrlTVSHYYQMI559292 intact-crc:A8F73AD74FAA22C0|rigid:ULQ0DjxYtLfv8xe5UfXwAJJ8pPg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09620 uniprotkb:Q12270 intact:EBI-9653|ensemblfungi:YGL203C|uniprotkb:D6VTV1 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:kex1_yeast(display_long)|uniprotkb:KEX1(gene name)|psi-mi:KEX1(display_short)|uniprotkb:Carboxypeptidase D(gene name synonym)|uniprotkb:Killer expression defective protein 1(gene name synonym)|uniprotkb:YGL203C(locus name) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347439|imex:IM-14275-3046 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL203C(gene)|ensemblfungi:YGL203C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:1AC5|refseq:NP_011312.1|sgd:S000003171|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR033124|interpro:IPR029058|mint:P09620 refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R6uP/9o38goNzIvIX0SQKjONH/8559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:AA79012611DE07F2|rigid:aQQDxgbut29YnPR2Bhk5tDsD0cE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:Q12270 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347450|imex:IM-14275-3047 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:F8B7100AE998637D|rigid:1r7glq/LkA7DOI1GQvK1rEh7Q94 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:Q12270 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347461|imex:IM-14275-3048 author score:98.18 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:98.18|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:4D11E2B64A4659D1|rigid:NAaE4wK0R28ffpl1yo6uCqvAaxU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25361 uniprotkb:Q12270 intact:EBI-21909|uniprotkb:D6VR52|ensemblfungi:YCR043C intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:yct3_yeast(display_long)|uniprotkb:YCR43C(orf name)|uniprotkb:YCR725(orf name)|uniprotkb:YCR043C(locus name) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347472|imex:IM-14275-3049 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000639|refseq:NP_009972.1|mint:P25361|ensemblfungi:YCR043C(gene)|ensemblfungi:YCR043C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0043332"(mating projection tip) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:bEMtsAa5vCsWqGOiXwBK40Pa0xQ559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:44DA0DA07C440659|rigid:0xjlxEnAQrshSOAu6yHoJgbDzIQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32074 uniprotkb:Q12270 intact:EBI-4891|ensemblfungi:YNL287W|uniprotkb:D6W0Q6 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:copg_yeast(display_long)|uniprotkb:SEC21(gene name)|psi-mi:SEC21(display_short)|uniprotkb:YNL287W(locus name)|uniprotkb:N0543(orf name)|uniprotkb:Gamma-coat protein(gene name synonym) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347483|imex:IM-14275-3050 author score:98.75 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|ensemblfungi:YNL287W(gene)|ensemblfungi:YNL287W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|refseq:NP_014112.1|sgd:S000005231|dip:DIP-1611N|mint:P32074|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) crc64:99DC7D737D4EF761 - figure legend:tables S3 and S4|author-confidence:98.75|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:uAs2hcx4DNS58qP1YDaUKgqZQm0559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:63C8A86E50DB5E37|rigid:e5fgsyxqBpABtBFvJ/mqCATQaxQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:P36164 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-26527|uniprotkb:D6VXE8|ensemblfungi:YKR088C psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:tvp38_yeast(display_long)|uniprotkb:YKR408(orf name)|uniprotkb:YKR088C(locus name)|uniprotkb:TVP38(gene name)|psi-mi:TVP38(display_short)|uniprotkb:TLG2-vesicle protein of 38 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347494|imex:IM-14275-3051 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 sgd:S000001796|refseq:NP_013014.3|mint:P36164|dip:DIP-5167N|interpro:IPR032816|ensemblfungi:YKR088C(gene)|ensemblfungi:YKR088C_mRNA(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0005737"(cytoplasm)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane) psi-mi:"MI:0469"(intact) - crc64:7EA95DD4E5AF77FE figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:wNtRh3eKqVkQKwO9QmrJHjSSdnk559292 intact-crc:45BD722A55D28823|rigid:8lSLk/R32jeNqT2kNF871fMdJ9U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38084 uniprotkb:Q12270 intact:EBI-3414|uniprotkb:D6VQ67|ensemblfungi:YBR068C intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:bap2_yeast(display_long)|uniprotkb:Branched-chain amino-acid permease 2(gene name synonym)|uniprotkb:BAP2(gene name)|psi-mi:BAP2(display_short)|uniprotkb:YBR068C(locus name)|uniprotkb:YBR0629(orf name) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347505|imex:IM-14275-3052 author score:99.33 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000272|refseq:NP_009624.4|dip:DIP-4910N|mint:P38084|ensemblfungi:YBR068C(gene)|ensemblfungi:YBR068C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015192"(L-phenylalanine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098713"(leucine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) crc64:B87FD6A7464E07F5 - figure legend:tables S3 and S4|author-confidence:99.33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:7Fw7+M5mBikZBztHE2tSDpvBi/M559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:E0E8AB646BB2D2AD|rigid:ijwNpfLESFxzb7g7yCw4guL8OdY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:P38166 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347516|imex:IM-14275-3053 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166 psi-mi:"MI:0469"(intact) - crc64:1BF971749814382C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292 intact-crc:E44B18BD2F2186C3|rigid:Wk0LrYWHVPYc5k5GbFUHW1bGL2s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38682 uniprotkb:Q12270 intact:EBI-7679|uniprotkb:D3DM28|ensemblfungi:YER122C intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:glo3_yeast(display_long)|uniprotkb:YER122C(locus name)|uniprotkb:GLO3(gene name)|psi-mi:GLO3(display_short) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347527|imex:IM-14275-3054 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011048.1|sgd:S000000924|mint:P38682|dip:DIP-2740N|ensemblfungi:YER122C(gene)|ensemblfungi:YER122C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048205"(COPI coating of Golgi vesicle)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR037278|interpro:IPR038508|rcsb pdb:7JTZ|reactome:R-SCE-6811434 refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:wrmKBOu6fRAJt5NubLMLzVr64hs559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:908D2CCFE4BC0C34|rigid:yvE0HkFflYijE+obJcYqk82RapY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:P38810 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-17012|uniprotkb:D3DL48|ensemblfungi:YHR098C psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:sfb3_yeast(display_long)|uniprotkb:SFB3(gene name)|psi-mi:SFB3(display_short)|uniprotkb:SEC24-related protein 3(gene name synonym)|uniprotkb:Lethal with SEC13 protein 1(gene name synonym)|uniprotkb:LST1(gene name synonym)|uniprotkb:YHR098C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347538|imex:IM-14275-3055 author score:99.36 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 refseq:NP_011966.1|sgd:S000001140|ensemblfungi:YHR098C(gene)|ensemblfungi:YHR098C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|interpro:IPR036174|go:"GO:0030127"(COPII vesicle coat)|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0043332"(mating projection tip)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071944"(cell periphery)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|dip:DIP-2949N|mint:P38810 psi-mi:"MI:0469"(intact) - crc64:6A028AD6B1A2E031 figure legend:tables S3 and S4|author-confidence:99.36|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:+UqTvqDtF6TcA3pcbFJfvzKsoyc559292 intact-crc:27FDD376BF27ED33|rigid:s7KeOfz58jauR/p+mqwvsv3oI2o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39010 uniprotkb:Q12270 intact:EBI-2421|uniprotkb:D6VSP8|ensemblfungi:YDR264C intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:akr1_yeast(display_long)|uniprotkb:AKR1(gene name)|psi-mi:AKR1(display_short)|uniprotkb:YDR264C(locus name)|uniprotkb:D9954.9(orf name)|uniprotkb:YD9230B.03C(orf name)|uniprotkb:Ankyrin repeat-containing protein AKR1(gene name synonym) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347549|imex:IM-14275-3056 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010550.1|sgd:S000002672|dip:DIP-1145N|mint:P39010|ensemblfungi:YDR264C(gene)|ensemblfungi:YDR264C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0090029"(negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:INuSfspu5JYfFnlcgzVdvDeTerU559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:DD7D96C7BF020242|rigid:VkjEuMHQIt7fUvF+SXnnvXTeBpc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:P40071 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-22657|uniprotkb:D3DM19|ensemblfungi:YER113C psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:tmn3_yeast(display_long)|uniprotkb:YER113C(locus name)|uniprotkb:TMN3(gene name)|psi-mi:TMN3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347560|imex:IM-14275-3057 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 refseq:NP_011038.3|sgd:S000000915|dip:DIP-849N|mint:P40071|ensemblfungi:YER113C(gene)|ensemblfungi:YER113C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006811"(ion transport)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0072657"(protein localization to membrane)|interpro:IPR004240("Nonaspanin (TM9SF)") psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:8BxN4sGvO60kSO6ApFWZmiaQjAI559292 intact-crc:D30E79463EF4AE18|rigid:f4sRvHwyiQK5C9cIQ3hJagHG3eA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40094 uniprotkb:Q12270 intact:EBI-16605|ensemblfungi:YER157W|uniprotkb:D3DM64 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:cog3_yeast(display_long)|uniprotkb:COG3(gene name)|psi-mi:COG3(display_short)|uniprotkb:GRD20(gene name synonym)|uniprotkb:SEC34(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 3(gene name synonym)|uniprotkb:Protein SEC34(gene name synonym)|uniprotkb:YER157W(locus name) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347571|imex:IM-14275-3058 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER157W(gene)|ensemblfungi:YER157W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR007265(Sec34-like protein)|refseq:NP_011084.1|sgd:S000000959|dip:DIP-4728N|mint:P40094 refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) crc64:C7AFBE99010FE571 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:R2r0ZW+nxrykdTHq1cJy9zOmvHo559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:1E4DFA30480F8EC1|rigid:yYCVCB8hXAOXIFMUigZBlZMJaMU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40582 uniprotkb:Q12270 intact:EBI-7941|uniprotkb:D6VVW9|ensemblfungi:YIR038C intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:gst1_yeast(display_long)|uniprotkb:YIR038C(locus name)|uniprotkb:GTT1(gene name)|psi-mi:GTT1(display_short)|uniprotkb:GST-I(gene name synonym) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347582|imex:IM-14275-3059 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012304.1|sgd:S000001477|mint:P40582|dip:DIP-2103N|ensemblfungi:YIR038C(gene)|ensemblfungi:YIR038C_mRNA(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010731"(protein glutathionylation)|go:"GO:0071944"(cell periphery)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079 refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) crc64:3C07D40D29F60DFF - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+bqzHpsoLw4j2qQBzHbkfldR5OU559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:E2796C4BC3B1EE4A|rigid:PgtsNRnHhLHLkERqnxVjqdZ9qNI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41810 uniprotkb:Q12270 intact:EBI-4869|uniprotkb:Q03779|uniprotkb:D6VSL9|ensemblfungi:YDR238C intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:copb_yeast(display_long)|uniprotkb:SEC26(gene name)|psi-mi:SEC26(display_short)|uniprotkb:YDR238C(locus name)|uniprotkb:YD8419.05C(orf name)|uniprotkb:Beta-coat protein(gene name synonym) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347593|imex:IM-14275-3060 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002646|refseq:NP_010524.3|dip:DIP-6467N|mint:P41810|ensemblfungi:YDR238C(gene)|ensemblfungi:YDR238C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|reactome:R-SCE-6798695|reactome:R-SCE-6807878|reactome:R-SCE-6811434 refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) crc64:885420DB026BCFA3 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ZfLp1BUmvVuTiXn7/Zbf/3m6VtE559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:FBC01D439827CC7A|rigid:Vy1dwaneqRIzTxEUzw7evTJazgc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:P41811 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347604|imex:IM-14275-3061 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - crc64:6A5E50BBEB02CB58 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:FAC01D47255E5438|rigid:5Qmp5xuQQvyh7i+tcX0eYRITWps false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:P43621 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-4876|uniprotkb:D6VTT4|ensemblfungi:YFR051C psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:copd_yeast(display_long)|uniprotkb:RET2(gene name)|psi-mi:RET2(display_short)|uniprotkb:YFR051C(locus name)|uniprotkb:Delta-coat protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347615|imex:IM-14275-3062 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 sgd:S000001947|refseq:NP_116709.3|dip:DIP-5255N|mint:P43621|ensemblfungi:YFR051C(gene)|ensemblfungi:YFR051C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|rcsb pdb:5FJW|rcsb pdb:5FJX|rcsb pdb:5FJZ|rcsb pdb:5FK0|reactome:R-SCE-6807878|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - crc64:AA730F046655EE5A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:auvjuT8ffm1R4P3mRKEIWAsynW0559292 intact-crc:11868D8528A7B333|rigid:sUpRZFljDhLhNEeSgBeYeDFss+Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46989 uniprotkb:Q12270 intact:EBI-26164|uniprotkb:Q86ZR9|uniprotkb:D6VW11|ensemblfungi:YJL178C intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:atg27_yeast(display_long)|uniprotkb:ETF1(gene name synonym)|uniprotkb:J0490(orf name)|uniprotkb:YJL178C(locus name)|uniprotkb:ATG27(gene name)|psi-mi:ATG27(display_short)|uniprotkb:Enhancer of VPS34 missorting protein 1(gene name synonym) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347626|imex:IM-14275-3063 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012357.2|sgd:S000003714|mint:P46989|dip:DIP-1606N|ensemblfungi:YJL178C(gene)|ensemblfungi:YJL178C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR018939|interpro:IPR044865|reactome:R-SCE-6798695|reactome:R-SCE-8856825|reactome:R-SCE-8856828 refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YJcEIILRs1JMXscIACBN/T2+1PE559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:19BEF045EFC08139|rigid:Xr4eXBQJEM0oZQiWm5E4Gnm0Iqk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54858 uniprotkb:Q12270 intact:EBI-6042|uniprotkb:D6VS54|ensemblfungi:YDR068W intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:dos2_yeast(display_long)|uniprotkb:D4267(orf name)|uniprotkb:YD8554.01(orf name)|uniprotkb:YD9609.22(orf name)|uniprotkb:DOS2(gene name)|psi-mi:DOS2(display_short)|uniprotkb:YDR068W(locus name) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347637|imex:IM-14275-3064 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002475|refseq:NP_010353.3|dip:DIP-4785N|mint:P54858|ensemblfungi:YDR068W(gene)|ensemblfungi:YDR068W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR005607(BSD)|interpro:IPR035925 refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:/4fnAAPmC12DMUbUB8MVS9yjjeg559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:CBFCB16C001EFE47|rigid:MsMYPhMeNv4t9WPKuJbTBLc7Xk8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:Q03687 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-28024|uniprotkb:D6VZI4|ensemblfungi:YMR010W psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:any1_yeast(display_long)|uniprotkb:ANY1(gene name)|psi-mi:ANY1(display_short)|uniprotkb:Antagonizes NEO1 phospholipid flippase protein 1(gene name synonym)|uniprotkb:CDC50 suppressor 1(gene name synonym)|uniprotkb:CFS1(gene name synonym)|uniprotkb:YM8270.13(orf name)|uniprotkb:YMR010W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347648|imex:IM-14275-3065 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 refseq:NP_013723.1|sgd:S000004612|dip:DIP-4512N|mint:Q03687|ensemblfungi:YMR010W(gene)|ensemblfungi:YMR010W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR006603(Cystinosin/ERS1p repeat) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:1MFVfZzqs2y94E4EOyTdidRjc7Q559292 intact-crc:4A84CBDDE042DD5F|rigid:Nb2Iz/SFJnDAMWjUl6cduZdWKgs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:Q03730 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-27739|uniprotkb:Q6B2K7|uniprotkb:D6VZF6|ensemblfungi:YML018C psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:ymb8_yeast(display_long)|uniprotkb:YML018C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347659|imex:IM-14275-3066 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 sgd:S000004480|refseq:NP_013694.1|dip:DIP-4953N|mint:Q03730|ensemblfungi:YML018C(gene)|ensemblfungi:YML018C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - crc64:DEC5C3EEF293F5ED figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:4WxEFdhqbP7pcRcTLeFHljCVQ34559292 intact-crc:29C11812FA06EF82|rigid:L8CwFT3uM9mqmSczuyiXK/F+X/s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:Q03860 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347670|imex:IM-14275-3067 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) psi-mi:"MI:0469"(intact) - crc64:395F700FBB14C569 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 intact-crc:44D285C2EC74A9DB|rigid:sitghYqjSF4eyZzFrKmUIxctKQQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:Q04396 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-35436|uniprotkb:D6VTC5|ensemblfungi:YDR503C psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:lpp1_yeast(display_long)|uniprotkb:LPP1(gene name)|psi-mi:LPP1(display_short)|uniprotkb:YDR503C(locus name)|uniprotkb:D9719.9(orf name)|uniprotkb:Phosphatidate phosphatase(gene name synonym)|uniprotkb:Lysophosphatidate phosphatase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347681|imex:IM-14275-3068 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 refseq:NP_010791.3|sgd:S000002911|mint:Q04396|dip:DIP-1415N|ensemblfungi:YDR503C(gene)|ensemblfungi:YDR503C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000810"(diacylglycerol diphosphate phosphatase activity)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042577"(lipid phosphatase activity)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR043216|reactome:R-SCE-1660661|reactome:R-SCE-2029485|reactome:R-SCE-419408 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:WSLmGL9DQuSCqyVf3vQjK753VsI559292 intact-crc:E04BB19E59906B28|rigid:jJvm2Fj2dORuTs5Dfu4a8Y/LKDk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04410 uniprotkb:Q12270 intact:EBI-32083|uniprotkb:D6VTD8|ensemblfungi:YDR517W intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:grh1_yeast(display_long)|uniprotkb:GRH1(gene name)|psi-mi:GRH1(display_short)|uniprotkb:YDR517W(locus name) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347692|imex:IM-14275-3069 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010805.1|sgd:S000002925|dip:DIP-6613N|mint:Q04410|ensemblfungi:YDR517W(gene)|ensemblfungi:YDR517W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0009306"(protein secretion)|go:"GO:0031090"(organelle membrane)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR007583(GRASP55/65)|interpro:IPR024958|interpro:IPR036034|rcsb pdb:6G8Y|reactome:R-SCE-162658|reactome:R-SCE-204005 refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) crc64:A7CE62DFE4631214 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Tj4Jf1BeT57ROzFoNoi+g9GLuYk559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:45CB85E5F371C40A|rigid:aW5BenPuFq1CZa6PcVmylA5eAO8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:Q06096 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-4823|uniprotkb:D6W4A3|ensemblfungi:YPR105C psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:cog4_yeast(display_long)|uniprotkb:COG4(gene name)|psi-mi:COG4(display_short)|uniprotkb:SEC38(gene name synonym)|uniprotkb:YPR105C(locus name)|uniprotkb:P8283.16(orf name)|uniprotkb:SGF1(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 4(gene name synonym)|uniprotkb:Protein SEC38(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347703|imex:IM-14275-3070 author score:99.27 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 refseq:NP_015430.1|sgd:S000006309|dip:DIP-2003N|mint:Q06096|ensemblfungi:YPR105C(gene)|ensemblfungi:YPR105C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0005829"(cytosol)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|interpro:IPR013167(COG4 transport) psi-mi:"MI:0469"(intact) - crc64:22F265AB2AD91533 figure legend:tables S3 and S4|author-confidence:99.27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:ZsM2iBiMekDXsSPQKbfiWoVXnMU559292 intact-crc:9887CC5C599DA5D8|rigid:WswD89CIGIlSbMDVHxMgPwUPXXo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:Q12270 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347714|imex:IM-14275-3071 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 intact-crc:8294A4749788714B|rigid:OMLm26dSr0TwLiJa7VPjrTHarAE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12271 uniprotkb:P22137 intact:EBI-36688|uniprotkb:D6W2G8|ensemblfungi:YOR109W intact:EBI-4766|uniprotkb:D6VTU9|ensemblfungi:YGL206C psi-mi:inp53_yeast(display_long)|uniprotkb:Synaptojanin-like protein 3(gene name synonym)|uniprotkb:Suppressor of PMA1 protein 2(gene name synonym)|uniprotkb:INP53(gene name)|psi-mi:INP53(display_short)|uniprotkb:SJL3(gene name synonym)|uniprotkb:SOP2(gene name synonym)|uniprotkb:YOR3231w(orf name)|uniprotkb:YOR109W(locus name) psi-mi:clh_yeast(display_long)|uniprotkb:CHC1(gene name)|psi-mi:CHC1(display_short)|uniprotkb:YGL206C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347725|imex:IM-14275-3072 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005635|refseq:NP_014752.3|mint:Q12271|dip:DIP-2555N|ensemblfungi:YOR109W(gene)|ensemblfungi:YOR109W_mRNA(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR002013(Synaptojanin, N-terminal)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|reactome:R-SCE-1660499|reactome:R-SCE-1855183|reactome:R-SCE-1855204|reactome:R-SCE-8856828 refseq:NP_011309.1|sgd:S000003174|dip:DIP-2279N|mint:P22137|ensemblfungi:YGL206C(gene)|ensemblfungi:YGL206C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0071439"(clathrin complex)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-432720|reactome:R-SCE-437239|reactome:R-SCE-8856828|reactome:R-SCE-8866427|reactome:R-SCE-8964038 psi-mi:"MI:0469"(intact) - crc64:622F3083DF2FE315 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:99bi0oSA0ftzn4Tyu4QHo0OKgZI559292 rogid:SAN6H3nVFozXZyTiRLaljMcIKIA559292 intact-crc:C3A048BAC0E4F3B9|rigid:yVq8ENL8NqQMmv75L7vAGD7bBu4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12271 uniprotkb:P36000 intact:EBI-36688|uniprotkb:D6W2G8|ensemblfungi:YOR109W intact:EBI-2206|uniprotkb:D6VX61|ensemblfungi:YKL135C psi-mi:inp53_yeast(display_long)|uniprotkb:Synaptojanin-like protein 3(gene name synonym)|uniprotkb:Suppressor of PMA1 protein 2(gene name synonym)|uniprotkb:INP53(gene name)|psi-mi:INP53(display_short)|uniprotkb:SJL3(gene name synonym)|uniprotkb:SOP2(gene name synonym)|uniprotkb:YOR3231w(orf name)|uniprotkb:YOR109W(locus name) psi-mi:ap1b1_yeast(display_long)|uniprotkb:APL2(gene name)|psi-mi:APL2(display_short)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta-1 large chain(gene name synonym)|uniprotkb:Clathrin assembly protein large beta-1 chain(gene name synonym)|uniprotkb:YKL135C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347736|imex:IM-14275-3073 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005635|refseq:NP_014752.3|mint:Q12271|dip:DIP-2555N|ensemblfungi:YOR109W(gene)|ensemblfungi:YOR109W_mRNA(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR002013(Synaptojanin, N-terminal)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|reactome:R-SCE-1660499|reactome:R-SCE-1855183|reactome:R-SCE-1855204|reactome:R-SCE-8856828 refseq:NP_012787.1|sgd:S000001618|dip:DIP-1199N|mint:P36000|ensemblfungi:YKL135C(gene)|ensemblfungi:YKL135C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030121"(AP-1 adaptor complex)|go:"GO:0030276"(clathrin binding)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|reactome:R-SCE-432720|reactome:R-SCE-437239|reactome:R-SCE-8856825|reactome:R-SCE-8856828|reactome:R-SCE-8866427|reactome:R-SCE-8964038 psi-mi:"MI:0469"(intact) - crc64:89893945D4EC6C4A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:99bi0oSA0ftzn4Tyu4QHo0OKgZI559292 rogid:MKH8RySJV469TEWyuJCOuAitkJY559292 intact-crc:C3AA6ACE9E4B1F57|rigid:VwS5FlnJCUU3d1uPJwEOAuPaBS0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12271 uniprotkb:P38817 intact:EBI-36688|uniprotkb:D6W2G8|ensemblfungi:YOR109W intact:EBI-7569|uniprotkb:D3DL58|ensemblfungi:YHR108W psi-mi:inp53_yeast(display_long)|uniprotkb:Synaptojanin-like protein 3(gene name synonym)|uniprotkb:Suppressor of PMA1 protein 2(gene name synonym)|uniprotkb:INP53(gene name)|psi-mi:INP53(display_short)|uniprotkb:SJL3(gene name synonym)|uniprotkb:SOP2(gene name synonym)|uniprotkb:YOR3231w(orf name)|uniprotkb:YOR109W(locus name) psi-mi:gga2_yeast(display_long)|uniprotkb:YHR108W(locus name)|uniprotkb:GGA2(gene name)|psi-mi:GGA2(display_short)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347747|imex:IM-14275-3074 author score:99.32 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005635|refseq:NP_014752.3|mint:Q12271|dip:DIP-2555N|ensemblfungi:YOR109W(gene)|ensemblfungi:YOR109W_mRNA(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR002013(Synaptojanin, N-terminal)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|reactome:R-SCE-1660499|reactome:R-SCE-1855183|reactome:R-SCE-1855204|reactome:R-SCE-8856828 refseq:NP_011976.1|sgd:S000001150|mint:P38817|dip:DIP-2971N|ensemblfungi:YHR108W(gene)|ensemblfungi:YHR108W_mRNA(transcript)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|rcsb pdb:3MNM psi-mi:"MI:0469"(intact) - crc64:7AC3A317AEE302E2 figure legend:tables S3 and S4|author-confidence:99.32|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:99bi0oSA0ftzn4Tyu4QHo0OKgZI559292 rogid:stplLxS8A9T/NqdjQXRVJTxnRsI559292 intact-crc:BF42184FA8BF7AA9|rigid:f2Gzj+gNYIfq5cEcfw/a/61wA98 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12028 uniprotkb:Q12271 intact:EBI-33025|uniprotkb:D6W439|ensemblfungi:YPR029C intact:EBI-36688|uniprotkb:D6W2G8|ensemblfungi:YOR109W psi-mi:ap1g1_yeast(display_long)|uniprotkb:APL4(gene name)|psi-mi:APL4(display_short)|uniprotkb:Clathrin assembly protein complex 1 gamma large chain(gene name synonym)|uniprotkb:Clathrin assembly protein large gamma chain(gene name synonym)|uniprotkb:Gamma-adaptin(gene name synonym)|uniprotkb:YPR029C(locus name) psi-mi:inp53_yeast(display_long)|uniprotkb:Synaptojanin-like protein 3(gene name synonym)|uniprotkb:Suppressor of PMA1 protein 2(gene name synonym)|uniprotkb:INP53(gene name)|psi-mi:INP53(display_short)|uniprotkb:SJL3(gene name synonym)|uniprotkb:SOP2(gene name synonym)|uniprotkb:YOR3231w(orf name)|uniprotkb:YOR109W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347758|imex:IM-14275-3075 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015354.1|sgd:S000006233|mint:Q12028|dip:DIP-3913N|ensemblfungi:YPR029C(gene)|ensemblfungi:YPR029C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030121"(AP-1 adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017107(Adaptor protein complex AP-1, gamma subunit)|reactome:R-SCE-432720 sgd:S000005635|refseq:NP_014752.3|mint:Q12271|dip:DIP-2555N|ensemblfungi:YOR109W(gene)|ensemblfungi:YOR109W_mRNA(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR002013(Synaptojanin, N-terminal)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|reactome:R-SCE-1660499|reactome:R-SCE-1855183|reactome:R-SCE-1855204|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:ABB619E9DC4F565C - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nzjklmQlRHNY/Wqmrg6GbLG17e8559292 rogid:99bi0oSA0ftzn4Tyu4QHo0OKgZI559292 intact-crc:DBD7974F519C3C8B|rigid:bH1RlGcwP/TfaVcuTf71w2oP/Zw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53131 uniprotkb:Q12277 intact:EBI-505|ensemblfungi:YGL120C|uniprotkb:D6VU28 intact:EBI-1765|uniprotkb:D6VRN9|ensemblfungi:YDL111C psi-mi:prp43_yeast(display_long)|uniprotkb:PRP43(gene name)|psi-mi:PRP43(display_short)|uniprotkb:Helicase JA1(gene name synonym)|uniprotkb:YGL120C(locus name) psi-mi:rrp42_yeast(display_long)|uniprotkb:RRP42(gene name)|psi-mi:RRP42(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:YDL111C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347769|imex:IM-14275-3076 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|rcsb pdb:2XAU|rcsb pdb:3KX2|rcsb pdb:5I8Q|rcsb pdb:5JPT|rcsb pdb:5Y88|refseq:NP_011395.1|sgd:S000003088|ensemblfungi:YGL120C(gene)|ensemblfungi:YGL120C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|dip:DIP-5152N|mint:P53131 refseq:NP_010172.1|sgd:S000002269|dip:DIP-1463N|mint:Q12277|ensemblfungi:YDL111C(gene)|ensemblfungi:YDL111C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) crc64:DA8A085EC50FF430 crc64:806C60979642C67E figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:45MX/uTINAjulwkB0vGKeimS+8c559292 rogid:OVyAr6b3ECMjQj3nUsuxXZqxt1o559292 intact-crc:87F96748B4C8636D|rigid:59z3gt6YSbq7UEeGtyh5Pfuc/Jc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CX10 uniprotkb:Q12289 intact:EBI-6315262|ensemblfungi:YOR393W|ensemblfungi:YPL281C|uniprotkb:D6W385|uniprotkb:Q12007|uniprotkb:Q7LGJ4 intact:EBI-5145|uniprotkb:D6W2G1|ensemblfungi:YOR100C psi-mi:err1_yeast(display_long)|uniprotkb:ERR1(gene name)|psi-mi:ERR1(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:2-phosphoglycerate dehydratase(gene name synonym)|uniprotkb:YOR393W(locus name) psi-mi:crc1_yeast(display_long)|uniprotkb:CRC1(gene name)|psi-mi:CRC1(display_short)|uniprotkb:YOR3193C(orf name)|uniprotkb:YOR100C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347780|imex:IM-14275-3077 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR393W(gene)|ensemblfungi:YOR393W_mRNA(transcript)|ensemblfungi:YPL281C(gene)|ensemblfungi:YPL281C_mRNA(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0006096"(glycolytic process)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|reactome:R-SCE-70171|reactome:R-SCE-70263|mint:P0CX10|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|refseq:NP_015038.1|refseq:NP_015042.1|sgd:S000005920|interpro:IPR029017|interpro:IPR036849 refseq:NP_014743.1|sgd:S000005626|dip:DIP-4154N|mint:Q12289|ensemblfungi:YOR100C(gene)|ensemblfungi:YOR100C_mRNA(transcript)|go:"GO:0005476"("carnitine:acyl carnitine antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395|reactome:R-SCE-200425 psi-mi:"MI:0469"(intact) - crc64:0CF982E858BD1EA5 figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Vusa5LQZe98ke/mcTRdEnXReZDc559292 rogid:DbjM7RHsYhxvTXtBy3h2OJBSZkk559292 intact-crc:0B532463DCA93C67|rigid:09J9rGT8qrFgyzLLZnxB5F3Zxbg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12315 uniprotkb:Q12315 intact:EBI-7635|uniprotkb:D6VRE7|ensemblfungi:YDL207W intact:EBI-7635|uniprotkb:D6VRE7|ensemblfungi:YDL207W psi-mi:gle1_yeast(display_long)|uniprotkb:BRR3(gene name synonym)|uniprotkb:RSS1(gene name synonym)|uniprotkb:YDL207W(locus name)|uniprotkb:D1049(orf name)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:Nuclear pore protein GLE1(gene name synonym)|uniprotkb:RNA export factor GLE1(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym) psi-mi:gle1_yeast(display_long)|uniprotkb:BRR3(gene name synonym)|uniprotkb:RSS1(gene name synonym)|uniprotkb:YDL207W(locus name)|uniprotkb:D1049(orf name)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:Nuclear pore protein GLE1(gene name synonym)|uniprotkb:RNA export factor GLE1(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347791|imex:IM-14275-3078 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002366|refseq:NP_010074.1|mint:Q12315|dip:DIP-2350N|ensemblfungi:YDL207W(gene)|ensemblfungi:YDL207W_mRNA(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:6B4E sgd:S000002366|refseq:NP_010074.1|mint:Q12315|dip:DIP-2350N|ensemblfungi:YDL207W(gene)|ensemblfungi:YDL207W_mRNA(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:6B4E psi-mi:"MI:0469"(intact) crc64:C9C6B1513AF95711 crc64:C9C6B1513AF95711 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:1RI51/DOenI6DQvh2tErmJnDffI559292 rogid:1RI51/DOenI6DQvh2tErmJnDffI559292 intact-crc:43F02B5FA9431B1F|rigid:FNe/AU8eMFTvoCR8s5lyFAgvgU4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12324 uniprotkb:Q12324 intact:EBI-33982|uniprotkb:Q08500|uniprotkb:Q7LGN3|uniprotkb:D6W2E9|ensemblfungi:YOR087W intact:EBI-33982|uniprotkb:Q08500|uniprotkb:Q7LGN3|uniprotkb:D6W2E9|ensemblfungi:YOR087W psi-mi:yvc1_yeast(display_long)|uniprotkb:YOR088W(orf name)|uniprotkb:YOR087W(locus name)|uniprotkb:YVC1(gene name)|psi-mi:YVC1(display_short)|uniprotkb:YOR3151W(orf name)|uniprotkb:Yeast vacuolar conductance protein 1(gene name synonym)|uniprotkb:TRP homolog(gene name synonym) psi-mi:yvc1_yeast(display_long)|uniprotkb:YOR088W(orf name)|uniprotkb:YOR087W(locus name)|uniprotkb:YVC1(gene name)|psi-mi:YVC1(display_short)|uniprotkb:YOR3151W(orf name)|uniprotkb:Yeast vacuolar conductance protein 1(gene name synonym)|uniprotkb:TRP homolog(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347802|imex:IM-14275-3079 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014730.2|sgd:S000005613|mint:Q12324|dip:DIP-4157N|ensemblfungi:YOR087W(gene)|ensemblfungi:YOR087W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005216"(ion channel activity)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005272"(sodium channel activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:1990816"(vacuole-mitochondrion membrane contact site)|interpro:IPR024862|rcsb pdb:6WHG|reactome:R-SCE-3295583 refseq:NP_014730.2|sgd:S000005613|mint:Q12324|dip:DIP-4157N|ensemblfungi:YOR087W(gene)|ensemblfungi:YOR087W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005216"(ion channel activity)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005272"(sodium channel activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:1990816"(vacuole-mitochondrion membrane contact site)|interpro:IPR024862|rcsb pdb:6WHG|reactome:R-SCE-3295583 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:9sMQkLwyXeGTJchkiADQckbQZZI559292 rogid:9sMQkLwyXeGTJchkiADQckbQZZI559292 intact-crc:FF0AEB6056674B43|rigid:Il4HBhGd6Ha2PqsWLmSdeKQl3yg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10823 uniprotkb:Q12335 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347813|imex:IM-14275-3080 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) crc64:881B91792AE91748 crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:5EA56B5696FE3935|rigid:sZS9M6fqPwAYoZGbnuS40qhtDkY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19807 uniprotkb:Q12335 intact:EBI-8409|uniprotkb:D6VU67|ensemblfungi:YGL077C intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:hnm1_yeast(display_long)|uniprotkb:YGL077C(locus name)|uniprotkb:HNM1(gene name)|psi-mi:HNM1(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CTR1(gene name synonym) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347824|imex:IM-14275-3081 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011438.1|sgd:S000003045|mint:P19807|dip:DIP-7965N|ensemblfungi:YGL077C(gene)|ensemblfungi:YGL077C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0034228"(ethanolamine transmembrane transporter activity)|go:"GO:0034229"(ethanolamine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1900749"("(R)-carnitine transport")|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004756(Amino acid permease subfamily)|interpro:IPR004840(Amino acid permease, conserved site) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) - crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FiBH5o16YuOHdiAMTRZyChHHMos559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:766EFF2D6A628A5B|rigid:E7zzUnwlmH16kaDPINw1Lb4zZJo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25623 uniprotkb:Q12335 intact:EBI-21900|uniprotkb:P25622|uniprotkb:Q96VH0|uniprotkb:D6VR40|ensemblfungi:YCR030C intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:syp1_yeast(display_long)|uniprotkb:YCR30C/YCR29C(orf name)|uniprotkb:YCR030C(locus name)|uniprotkb:SYP1(gene name)|psi-mi:SYP1(display_short) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347835|imex:IM-14275-3082 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009959.2|sgd:S000000626|mint:P25623|dip:DIP-1758N|ensemblfungi:YCR030C(gene)|ensemblfungi:YCR030C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032153"(cell division site)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0061645"(endocytic patch)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|rcsb pdb:3G9G|rcsb pdb:3G9H|reactome:R-SCE-8856828 refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) crc64:6F35C8F1562E41CC crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lMa0AmxS3qZsJizVjKTKwVbi9TE559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:E57E748234704BA9|rigid:jDUmZDWEbM8gHD1cInSCPCJYZPQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12335 uniprotkb:P26570 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347846|imex:IM-14275-3083 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N psi-mi:"MI:0469"(intact) crc64:1056E7A1F3E82288 crc64:8B7F009521F72C15 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 intact-crc:B1A9E62CE40FB6DB|rigid:XSmT8QG8eMfF0m5IlXxDnPYGE/I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12335 uniprotkb:P35735 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 intact:EBI-26678|uniprotkb:D6VXN6|ensemblfungi:YKL051W psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:sfk1_yeast(display_long)|uniprotkb:YKL051W(locus name)|uniprotkb:YKL303(orf name)|uniprotkb:SFK1(gene name)|psi-mi:SFK1(display_short)|uniprotkb:Suppressor of four kinase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347857|imex:IM-14275-3084 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N refseq:NP_012873.1|sgd:S000001534|mint:P35735|dip:DIP-5309N|ensemblfungi:YKL051W(gene)|ensemblfungi:YKL051W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007033"(vacuole organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0061093"(negative regulation of phospholipid translocation)|go:"GO:0071944"(cell periphery)|interpro:IPR019402 psi-mi:"MI:0469"(intact) crc64:1056E7A1F3E82288 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 rogid:MUFJgCWecmYI5IvVgC3UXQzptcY559292 intact-crc:BD4DEB76DF6CDEC0|rigid:HtNvIZzp6gB8/qHDLVc5xrRNXJc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12335 uniprotkb:P36027 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347868|imex:IM-14275-3085 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N psi-mi:"MI:0469"(intact) crc64:1056E7A1F3E82288 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 intact-crc:BEA3FDDCA13DA877|rigid:H95dXBj1GwwBynDvhn6fOh4xeqc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38009 uniprotkb:Q12335 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347879|imex:IM-14275-3086 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) crc64:8ABA71761B512242 crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:CD9232DCC4BEF6BF|rigid:kkOY0sjX15L8D+Cbj99kk0CD2D0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38234 uniprotkb:Q12335 intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347890|imex:IM-14275-3087 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039 refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) - crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:5CED279F62033DBE|rigid:teQgV4NJCFR8crQs7EmEOVlQp/A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12335 uniprotkb:P39719 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 intact:EBI-20703|uniprotkb:Q05165|uniprotkb:D6VPG5|ensemblfungi:YAL053W psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:flc2_yeast(display_long)|uniprotkb:YAL053W(locus name)|uniprotkb:FLC2(gene name)|psi-mi:FLC2(display_short)|uniprotkb:FAD transporter 2(gene name synonym)|uniprotkb:TRP-like ion channel FLC2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347901|imex:IM-14275-3088 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N refseq:NP_009348.2|sgd:S000000049|ensemblfungi:YAL053W(gene)|ensemblfungi:YAL053W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241|go:"GO:0055085"(transmembrane transport)|dip:DIP-6708N|mint:P39719 psi-mi:"MI:0469"(intact) crc64:1056E7A1F3E82288 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 rogid:NOmMW54DNa0o7vM945DlZgVUy44559292 intact-crc:57832DCDC83CB9F6|rigid:CvUbbtxhqpHB7VylvSqF9/r+uBY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40260 uniprotkb:Q12335 intact:EBI-10714|ensemblfungi:YGR121C|uniprotkb:D6VUQ2 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:mep1_yeast(display_long)|uniprotkb:MEP1(gene name)|psi-mi:MEP1(display_short)|uniprotkb:YGR121C(locus name)|uniprotkb:G6331(orf name)|uniprotkb:AMT1(gene name synonym) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347912|imex:IM-14275-3089 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR121C(gene)|ensemblfungi:YGR121C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|sgd:S000003353|refseq:NP_011636.3|mint:P40260|dip:DIP-5530N refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) - crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:VnoBl5jhQD24N0SbCLv68HCwl1U559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:ABCEA409A71DE6BB|rigid:+qN8y6NDH1eskIOtWXBZ2PqqymY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47072 uniprotkb:Q12335 intact:EBI-25803|uniprotkb:D6VWG2|uniprotkb:P47071|uniprotkb:Q86ZR5|ensemblfungi:YJL016W intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:yjb6_yeast(display_long)|uniprotkb:J1320(orf name)|uniprotkb:J1326(orf name)|uniprotkb:YJL017W(orf name)|uniprotkb:YJL016W(locus name) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347923|imex:IM-14275-3090 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003553|refseq:NP_012518.2|mint:P47072|dip:DIP-4907N|ensemblfungi:YJL016W(gene)|ensemblfungi:YJL016W_mRNA(transcript)|go:"GO:0005737"(cytoplasm) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) crc64:21D1541BCFEFDFF6 crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:XRf3g3pILUK7J16Tol90s1MoEY4559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:BA89E8F7D8EACA66|rigid:ozgmppsfml+KmuXHKVRTvuEgjXM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:Q12335 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347934|imex:IM-14275-3091 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) - crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:3D125AFD4C05CEAB|rigid:yu62QLsFCvdH20ASHVqinkhSUYg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12335 uniprotkb:P53049 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 intact:EBI-29324|uniprotkb:D6VV58|ensemblfungi:YGR281W psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:yor1_yeast(display_long)|uniprotkb:YOR1(gene name)|psi-mi:YOR1(display_short)|uniprotkb:ABC transporter YOR1(gene name synonym)|uniprotkb:"ABC-type Cd(2+) transporter"(gene name synonym)|uniprotkb:ABC-type glutathione-S-conjugate transporter(gene name synonym)|uniprotkb:YRS1(gene name synonym)|uniprotkb:Yeast oligomycin resistance protein 1(gene name synonym)|uniprotkb:YGR281W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347945|imex:IM-14275-3092 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N sgd:S000003513|refseq:NP_011797.3|dip:DIP-6796N|mint:P53049|ensemblfungi:YGR281W(gene)|ensemblfungi:YGR281W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015434"(ABC-type cadmium transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030244|interpro:IPR036640|reactome:R-SCE-2142850|reactome:R-SCE-382556 psi-mi:"MI:0469"(intact) crc64:1056E7A1F3E82288 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 rogid:p71p+cqRzx+Iry0pb2s6q2DdPzA559292 intact-crc:786CA964986B38E9|rigid:R5W2FJrnwYu88w0dMpzPYw1zRHY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53139 uniprotkb:Q12335 intact:EBI-23908|uniprotkb:D6VU38|ensemblfungi:YGL108C intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:ygk8_yeast(display_long)|uniprotkb:G3070(orf name)|uniprotkb:YGL108C(locus name) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347956|imex:IM-14275-3093 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003076|refseq:NP_011407.3|mint:P53139|ensemblfungi:YGL108C(gene)|ensemblfungi:YGL108C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) - crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6rg2zcMN57peeKKy/RolIDcNaLc559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:0AA4C864875DE959|rigid:Om12NSPoNCOsIIaYDb2Zsa/gnnI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53278 uniprotkb:Q12335 intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347967|imex:IM-14275-3094 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) crc64:D482327C9274C026 crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:E5116B6028DC50F0|rigid:1M/ZUoKKYXC+lfju0Of/3e5OwlE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53390 uniprotkb:Q12335 intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347978|imex:IM-14275-3095 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) crc64:2309338F36D96258 crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:EBB1B895FD70F60A|rigid:osq4nvCsNddaOw7iH8RAh+Gh6sU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53832 uniprotkb:Q12335 intact:EBI-2055941|uniprotkb:D6W0R1|ensemblfungi:YNL283C intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:wsc2_yeast(display_long)|uniprotkb:YNL283C(locus name)|uniprotkb:N0583(orf name)|uniprotkb:WSC2(gene name)|psi-mi:WSC2(display_short) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6347989|imex:IM-14275-3096 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014116.1|sgd:S000005227|interpro:IPR002889(Carbohydrate-binding WSC)|mint:P53832|ensemblfungi:YNL283C(gene)|ensemblfungi:YNL283C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009408"(response to heat)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0043332"(mating projection tip) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) - crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5wadvTv6SxcIAb60yfnuGMfa8pY559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:7830A14CAB3AD53A|rigid:a4TF36z4QOfP7+btG320BjH6LJU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12335 uniprotkb:Q02201 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 intact:EBI-12636|uniprotkb:D6VXT9|ensemblfungi:YKR003W psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:osh6_yeast(display_long)|uniprotkb:YK102(orf name)|uniprotkb:YKR003W(locus name)|uniprotkb:OSH6(gene name)|psi-mi:OSH6(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348000|imex:IM-14275-3097 author score:97.53 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0015914"(phospholipid transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0120015"(sterol transfer activity)|rcsb pdb:4B2Z|rcsb pdb:4PH7|reactome:R-SCE-1482801|reactome:R-SCE-192105|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensemblfungi:YKR003W(gene)|ensemblfungi:YKR003W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|refseq:NP_012928.1|sgd:S000001711|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|mint:Q02201 psi-mi:"MI:0469"(intact) crc64:1056E7A1F3E82288 - figure legend:tables S3 and S4|author-confidence:97.53|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 rogid:aOZdSdLn96ns0C9w9E3r62iNyYo559292 intact-crc:7ABFEBFC631A62C0|rigid:NNawL/ByvsOJbu05a+Ax5z92kAA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12335 uniprotkb:Q02785 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 intact:EBI-13065|uniprotkb:D6W3V6|ensemblfungi:YPL058C psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:pdr12_yeast(display_long)|uniprotkb:PDR12(gene name)|psi-mi:PDR12(display_short)|uniprotkb:LPE14C(orf name)|uniprotkb:YPL058C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348011|imex:IM-14275-3098 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N refseq:NP_015267.1|sgd:S000005979|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR027417|interpro:IPR029481|mint:Q02785|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblfungi:YPL058C(gene)|ensemblfungi:YPL058C_mRNA(transcript)|go:"GO:0005342"(organic acid transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0015849"(organic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0071944"(cell periphery) psi-mi:"MI:0469"(intact) crc64:1056E7A1F3E82288 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 rogid:ADiU46Ad/dXDE9tXUfGj0rFIO6M559292 intact-crc:F0E7D99EBB218795|rigid:/kB7j4lBCRNm1JEKH4gkfNb7icw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12335 uniprotkb:Q03640 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348022|imex:IM-14275-3099 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) crc64:1056E7A1F3E82288 crc64:77A0AE57F9259784 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 intact-crc:607A57E9C4A4EDB8|rigid:5MgmKaXhMv4xf5ivn5UK/dRbtv8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05998 uniprotkb:Q12335 intact:EBI-19230|uniprotkb:P87335|uniprotkb:D6VYN5|ensemblfungi:YLR237W intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:thi7_yeast(display_long)|uniprotkb:THI7(gene name)|psi-mi:THI7(display_short)|uniprotkb:THI10(gene name synonym)|uniprotkb:YLR237W(locus name)|uniprotkb:L8083.2(orf name) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348033|imex:IM-14275-3100 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013338.1|sgd:S000004227|ensemblfungi:YLR237W(gene)|ensemblfungi:YLR237W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015205"(nucleobase transmembrane transporter activity)|go:"GO:0015851"(nucleobase transport)|go:"GO:0015888"(thiamine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1903088"(5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transport)|go:"GO:1903089"(5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transporter activity)|interpro:IPR001248(Permease for cytosine/purines, uracil, thiamine, allantoin)|interpro:IPR012681(Nucleobase cation symporter-1, NCS1)|go:"GO:0015234"(thiamine transmembrane transporter activity)|dip:DIP-4784N|mint:Q05998 refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) - crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hZvHdb/AbQ2e4q9krdwnvxs+CaY559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:02661B8A1CF1BEBC|rigid:XST4aFcvr0kGEFmGODdU9TsWNrU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06170 uniprotkb:Q12335 intact:EBI-35994|uniprotkb:D6VYW8|ensemblfungi:YLR326W intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:yl326_yeast(display_long)|uniprotkb:YLR326W(locus name) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348044|imex:IM-14275-3101 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013430.1|sgd:S000004318|mint:Q06170|dip:DIP-3995N|ensemblfungi:YLR326W(gene)|ensemblfungi:YLR326W_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR025187 refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) crc64:724CD7833AA9B416 crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Ufkoj1kRp4Y9JTsgbL+3k8hzJyo559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:A350220CC97C4334|rigid:NOPl+3dbGsB+YTlXigptNTyCRr4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06689 uniprotkb:Q12335 intact:EBI-38659|uniprotkb:D6VZ50|ensemblfungi:YLR413W intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:yl413_yeast(display_long)|uniprotkb:YLR413W(locus name) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348055|imex:IM-14275-3102 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013517.1|sgd:S000004405|mint:Q06689|dip:DIP-5075N|ensemblfungi:YLR413W(gene)|ensemblfungi:YLR413W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0071944"(cell periphery)|interpro:IPR009571(SUR7) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) crc64:92E23436DC857E95 crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AoTGKjLhw0NECrtuftZqLANonds559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:B5F3052DA50F8B01|rigid:4sldGX12nsNSm4xx7+abpkXt/6A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07651 uniprotkb:Q12335 intact:EBI-2051056|uniprotkb:D6VRD3|ensemblfungi:YDL222C intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:fmp45_yeast(display_long)|uniprotkb:YDL222C(locus name)|uniprotkb:FMP45(gene name)|psi-mi:FMP45(display_short) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348066|imex:IM-14275-3103 author score:97.40 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010059.1|sgd:S000002381|interpro:IPR009571(SUR7)|mint:Q07651|ensemblfungi:YDL222C(gene)|ensemblfungi:YDL222C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) - crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:97.40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:rjbW5/P8vNGue7zRlSdUQyZM6Lc559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:89E0ECA975401E97|rigid:jfxsECCQ1/cPZ56q2xqxcbTj/mQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08967 uniprotkb:Q12335 intact:EBI-36673|uniprotkb:D6W3E9|ensemblfungi:YPL221W intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:flc1_yeast(display_long)|uniprotkb:FAD transporter 1(gene name synonym)|uniprotkb:FLC1(gene name)|psi-mi:FLC1(display_short)|uniprotkb:TRP-like ion channel protein FLC1(gene name synonym)|uniprotkb:Heme utilization factor 1(gene name synonym)|uniprotkb:Bypass of PAM1 protein 1(gene name synonym)|uniprotkb:HUF1(gene name synonym)|uniprotkb:YPL221W(locus name)|uniprotkb:BOP1(gene name synonym) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348077|imex:IM-14275-3104 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015103.1|sgd:S000006142|mint:Q08967|dip:DIP-3965N|ensemblfungi:YPL221W(gene)|ensemblfungi:YPL221W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006457"(protein folding)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0015230"(FAD transmembrane transporter activity)|go:"GO:0015883"(FAD transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0055085"(transmembrane transport)|interpro:IPR010308(Protein of unknown function DUF907, fungi)|interpro:IPR032800|interpro:IPR040241 refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) - crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:r6CcZGEjxHUk2w0iBUBvnAPaFd4559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:DFBB325DFF8826CA|rigid:ouQBC2U9ry2vEsAaw4YobkD3eKk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12256 uniprotkb:Q12335 intact:EBI-37213|uniprotkb:D6W2X3|ensemblfungi:YOR273C intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:tpo4_yeast(display_long)|uniprotkb:TPO4(gene name)|psi-mi:TPO4(display_short)|uniprotkb:O5440(orf name)|uniprotkb:YOR273C(locus name) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348088|imex:IM-14275-3105 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014916.1|sgd:S000005799|mint:Q12256|dip:DIP-4096N|ensemblfungi:YOR273C(gene)|ensemblfungi:YOR273C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015606"(spermidine transmembrane transporter activity)|go:"GO:0015848"(spermidine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) - crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:0b5bKjS3gQ/O9NkoLugh6okqwOs559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:E0E5C27C2E1E34F3|rigid:/Ugdsv/PwBZiXlLalHTfSuDE13M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12335 uniprotkb:Q12335 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348099|imex:IM-14275-3106 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) crc64:1056E7A1F3E82288 crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:7F8D5949EC720093|rigid:FBdVCWSad9XI4lsMaXGnQ2NnSAg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3E756 uniprotkb:Q12335 intact:EBI-2044812|uniprotkb:D6VPX0|ensemblfungi:YBL029C-A intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:yb029_yeast(display_long)|uniprotkb:YBL029C-A(locus name) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348110|imex:IM-14275-3107 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000007591|refseq:NP_076874.1|mint:Q3E756|ensemblfungi:YBL029C-A(gene)|ensemblfungi:YBL029C-A_mRNA(transcript)|go:"GO:0005886"(plasma membrane) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N psi-mi:"MI:0469"(intact) - crc64:1056E7A1F3E82288 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Y9LDkESr65DK5SLFNTw1dBKeqPc559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 intact-crc:1C0026D4381243ED|rigid:jF/uEEw1iA0eZcL5BWGsGCWMSHU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23202 uniprotkb:Q12361 intact:EBI-20138|uniprotkb:D6W0W3|ensemblfungi:YNL229C intact:EBI-7844|uniprotkb:D6VRV9|ensemblfungi:YDL035C psi-mi:ure2_yeast(display_long)|uniprotkb:URE2(gene name)|psi-mi:URE2(display_short)|uniprotkb:Disulfide reductase(gene name synonym)|uniprotkb:Glutathione peroxidase(gene name synonym)|uniprotkb:N1165(orf name)|uniprotkb:YNL229C(locus name) psi-mi:gpr1_yeast(display_long)|uniprotkb:GPR1(gene name)|psi-mi:GPR1(display_short)|uniprotkb:YDL035C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348121|imex:IM-14275-3108 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014170.1|sgd:S000005173|ensemblfungi:YNL229C(gene)|ensemblfungi:YNL229C_mRNA(transcript)|mint:P23202|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0010044"(response to aluminum ion)|go:"GO:0032447"(protein urmylation)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR017298(Prion URE2)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:1G6W|rcsb pdb:1G6Y|rcsb pdb:1HQO|rcsb pdb:1JZR|rcsb pdb:1K0A|rcsb pdb:1K0B|rcsb pdb:1K0C|rcsb pdb:1K0D|go:"GO:0003714"(transcription corepressor activity)|dip:DIP-1308N refseq:NP_010249.1|sgd:S000002193|dip:DIP-8949N|mint:Q12361|ensemblfungi:YDL035C_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005536"(glucose binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0009731"(detection of sucrose stimulus)|go:"GO:0009745"(sucrose mediated signaling)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051594"(detection of glucose)|interpro:IPR022596|interpro:IPR023041|ensemblfungi:YDL035C(gene) psi-mi:"MI:0469"(intact) crc64:2C628976034B0F1C - figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jjsWygBsEp8axNurMa3pxPMQJ2k559292 rogid:OVr7tP9gvgHz57bZuzRIGH+VSPg559292 intact-crc:D7C590AFA8B292C6|rigid:Rynw0yw+PJax2lQUIIAerP/QFN4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61830 uniprotkb:Q12373 intact:EBI-8098|uniprotkb:E9PAG1|uniprotkb:P02303|uniprotkb:P13996|uniprotkb:Q6B1U3|uniprotkb:Q6Q7G9|uniprotkb:D6VQ11|ensemblfungi:YBR010W|ensemblfungi:YNL031C intact:EBI-31911|uniprotkb:D6VXY2|ensemblfungi:YLL022C psi-mi:h3_yeast(display_long)|uniprotkb:SIN2(gene name synonym)|uniprotkb:YNL031C(locus name)|uniprotkb:N2749(orf name)|uniprotkb:HHT1(gene name)|psi-mi:HHT1(display_short)|uniprotkb:YBR010W(locus name)|uniprotkb:YBR0201(orf name)|uniprotkb:HHT2(gene name)|psi-mi:HHT2(display_short) psi-mi:hif1_yeast(display_long)|uniprotkb:HIF1(gene name)|psi-mi:HIF1(display_short)|uniprotkb:L1205(orf name)|uniprotkb:YLL022C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348132|imex:IM-14275-3109 author score:96.38 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009564.1|refseq:NP_014367.1|sgd:S000000214|sgd:S000004976|mint:P61830|dip:DIP-417N|ensemblfungi:YBR010W(gene)|ensemblfungi:YBR010W_mRNA(transcript)|ensemblfungi:YNL031C(gene)|ensemblfungi:YNL031C_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:1ID3|rcsb pdb:1M1D|rcsb pdb:1PEG|rcsb pdb:1PU9|rcsb pdb:1PUA|rcsb pdb:1QSN|rcsb pdb:2CNX|rcsb pdb:2H2G|rcsb pdb:2IDC|rcsb pdb:2JMJ|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:2RSN|rcsb pdb:3MP1|rcsb pdb:3MP6|rcsb pdb:3Q33|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6J2P|rcsb pdb:6KMJ|rcsb pdb:7K7G refseq:NP_013078.1|sgd:S000003945|dip:DIP-6442N|mint:Q12373|ensemblfungi:YLL022C(gene)|ensemblfungi:YLL022C_mRNA(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006348"|go:"GO:0016573"(histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:4NQ0|rcsb pdb:5BT1 psi-mi:"MI:0469"(intact) crc64:A6115FEB480AC67A crc64:B280CFCCB6896506 figure legend:tables S3 and S4|author-confidence:96.38|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jtDVNjrs2tJMmr/dqrvnNiQ2ppQ559292 rogid:4bOpAXdlDl6LtBQ+BjueT5/24aA559292 intact-crc:05EE209E3FF7F84A|rigid:xkLIoVjhyqGhiIpFfIoliQK5BtI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04062 uniprotkb:Q12377 intact:EBI-15944|uniprotkb:D6VT56|ensemblfungi:YDR427W intact:EBI-308|uniprotkb:D6VRQ3|ensemblfungi:YDL097C psi-mi:rpn9_yeast(display_long)|uniprotkb:RPN9(gene name)|psi-mi:RPN9(display_short)|uniprotkb:NAS7(gene name synonym)|uniprotkb:YDR427W(locus name)|uniprotkb:D9461.14(orf name)|uniprotkb:Proteasome non-ATPase subunit 7(gene name synonym) psi-mi:rpn6_yeast(display_long)|uniprotkb:RPN6(gene name)|psi-mi:RPN6(display_short)|uniprotkb:NAS4(gene name synonym)|uniprotkb:YDL097C(locus name)|uniprotkb:D2381(orf name)|uniprotkb:Proteasome non-ATPase subunit 4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348143|imex:IM-14275-3110 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002835|ensemblfungi:YDR427W(gene)|ensemblfungi:YDR427W_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043248"(proteasome assembly)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035298|interpro:IPR036390|interpro:IPR040798|rcsb pdb:2MQW|rcsb pdb:2MR3|rcsb pdb:2MRI|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|refseq:NP_010715.3|dip:DIP-5261N|mint:Q04062 refseq:NP_010186.1|sgd:S000002255|dip:DIP-1581N|mint:Q12377|ensemblfungi:YDL097C(gene)|ensemblfungi:YDL097C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043248"(proteasome assembly)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR036390|interpro:IPR040773|interpro:IPR040780|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168 psi-mi:"MI:0469"(intact) crc64:540F7DF8C23469A1 crc64:A8B1F7E6F73A4024 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hOAU0IY1VeRlmtX4Dw3MNJybZaE559292 rogid:Q7d0N0C4nR9dUZHh+zofzWAF/t8559292 intact-crc:612F6FA76449D3FB|rigid:/Cacp4TSn2hcUKPENdFr3Cf8SbQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08723 uniprotkb:Q12377 intact:EBI-36176|uniprotkb:Q6Q5I7|uniprotkb:D6W2W2|ensemblfungi:YOR261C intact:EBI-308|uniprotkb:D6VRQ3|ensemblfungi:YDL097C psi-mi:rpn8_yeast(display_long)|uniprotkb:RPN8(gene name)|psi-mi:RPN8(display_short)|uniprotkb:O5360(orf name)|uniprotkb:YOR261C(locus name) psi-mi:rpn6_yeast(display_long)|uniprotkb:RPN6(gene name)|psi-mi:RPN6(display_short)|uniprotkb:NAS4(gene name synonym)|uniprotkb:YDL097C(locus name)|uniprotkb:D2381(orf name)|uniprotkb:Proteasome non-ATPase subunit 4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348154|imex:IM-14275-3111 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005787|refseq:NP_014904.3|mint:Q08723|dip:DIP-1574N|ensemblfungi:YOR261C(gene)|ensemblfungi:YOR261C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4O8X|rcsb pdb:4O8Y|rcsb pdb:4OCL|rcsb pdb:4OCM|rcsb pdb:4OCN|rcsb pdb:4OWP|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5U4P|rcsb pdb:5W83|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168 refseq:NP_010186.1|sgd:S000002255|dip:DIP-1581N|mint:Q12377|ensemblfungi:YDL097C(gene)|ensemblfungi:YDL097C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043248"(proteasome assembly)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR036390|interpro:IPR040773|interpro:IPR040780|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168 psi-mi:"MI:0469"(intact) crc64:6EE6009545A3D0EF crc64:A8B1F7E6F73A4024 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:kvJ/LyyQGKi5JTh4Fek1kh70jOU559292 rogid:Q7d0N0C4nR9dUZHh+zofzWAF/t8559292 intact-crc:ED2B8E2FCBDAA8AA|rigid:UmK3jkFeD05F8D2NbT51xu93mIw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12250 uniprotkb:Q12377 intact:EBI-15935|uniprotkb:D6VRK1|ensemblfungi:YDL147W intact:EBI-308|uniprotkb:D6VRQ3|ensemblfungi:YDL097C psi-mi:rpn5_yeast(display_long)|uniprotkb:RPN5(gene name)|psi-mi:RPN5(display_short)|uniprotkb:NAS5(gene name synonym)|uniprotkb:YDL147W(locus name)|uniprotkb:D1572(orf name)|uniprotkb:Proteasome non-ATPase subunit 5(gene name synonym) psi-mi:rpn6_yeast(display_long)|uniprotkb:RPN6(gene name)|psi-mi:RPN6(display_short)|uniprotkb:NAS4(gene name synonym)|uniprotkb:YDL097C(locus name)|uniprotkb:D2381(orf name)|uniprotkb:Proteasome non-ATPase subunit 4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348165|imex:IM-14275-3112 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010134.1|sgd:S000002306|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035297|interpro:IPR036388|interpro:IPR036390|interpro:IPR040134|interpro:IPR040896|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:5ZMR|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:6FVX|ensemblfungi:YDL147W(gene)|ensemblfungi:YDL147W_mRNA(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0000502"(proteasome complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0034515"(proteasome storage granule)|rcsb pdb:6J2C|rcsb pdb:6FVY|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|dip:DIP-1578N|mint:Q12250 refseq:NP_010186.1|sgd:S000002255|dip:DIP-1581N|mint:Q12377|ensemblfungi:YDL097C(gene)|ensemblfungi:YDL097C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043248"(proteasome assembly)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR036390|interpro:IPR040773|interpro:IPR040780|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168 psi-mi:"MI:0469"(intact) crc64:E5DC7F8E6AE27736 crc64:A8B1F7E6F73A4024 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:DaeRxapE6TgoZG4emWRb3y12Vfc559292 rogid:Q7d0N0C4nR9dUZHh+zofzWAF/t8559292 intact-crc:1CE93007727408AF|rigid:eVCUTRnV5Gq+7rxYww6ii+qcjsI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12415 uniprotkb:P15496 intact:EBI-33456|uniprotkb:Q07347|uniprotkb:Q6B220|uniprotkb:D6W2G9|ensemblfungi:YOR110W intact:EBI-8902|ensemblfungi:YPL117C|uniprotkb:D6W3Q1 psi-mi:tfc7_yeast(display_long)|uniprotkb:TFIIIC 55 kDa subunit(gene name synonym)|uniprotkb:Transcription factor C subunit 7(gene name synonym)|uniprotkb:TFC7(gene name)|psi-mi:TFC7(display_short)|uniprotkb:YOR110W(locus name)|uniprotkb:YOR3234w(orf name)|uniprotkb:O3234(orf name) psi-mi:idi1_yeast(display_long)|uniprotkb:Isopentenyl pyrophosphate isomerase(gene name synonym)|uniprotkb:IDI1(gene name)|psi-mi:IDI1(display_short)|uniprotkb:BOT2(gene name synonym)|uniprotkb:YPL117C(locus name)|uniprotkb:LPH10C(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348176|imex:IM-14275-3113 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014753.1|sgd:S000005636|mint:Q12415|dip:DIP-2309N|ensemblfungi:YOR110W(gene)|ensemblfungi:YOR110W_mRNA(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR014623(Transcription factor TFIIIC, tau55 subunit)|interpro:IPR019481|interpro:IPR029033|rcsb pdb:2YN0|rcsb pdb:6YJ6 ensemblfungi:YPL117C(gene)|ensemblfungi:YPL117C_mRNA(transcript)|go:"GO:0004452"(isopentenyl-diphosphate delta-isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009240"(isopentenyl diphosphate biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0045337"(farnesyl diphosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050992"(dimethylallyl diphosphate biosynthetic process)|reactome:R-SCE-191273|refseq:NP_015208.1|sgd:S000006038|interpro:IPR011876(Isopentenyl-diphosphate delta-isomerase, type 1)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|mint:P15496 psi-mi:"MI:0469"(intact) crc64:D778B81F31B83C45 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mn2Bb2loTD9aj7c3jHjhe3C69/8559292 rogid:KQ9qSb2grQ4DQip7atYPeCwp5QM559292 intact-crc:F9C4599C8BC39F06|rigid:RaCLt0uBoCFvu9JA2XULyoYVBZs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38910 uniprotkb:Q12415 intact:EBI-4553|uniprotkb:E9P935|uniprotkb:D6W286|ensemblfungi:YOR020C intact:EBI-33456|uniprotkb:Q07347|uniprotkb:Q6B220|uniprotkb:D6W2G9|ensemblfungi:YOR110W psi-mi:ch10_yeast(display_long)|uniprotkb:HSP10(gene name)|psi-mi:HSP10(display_short)|uniprotkb:CPN10(gene name synonym)|uniprotkb:YOR020C(locus name)|uniprotkb:OR26.10(orf name)|uniprotkb:10 kDa chaperonin(gene name synonym) psi-mi:tfc7_yeast(display_long)|uniprotkb:TFIIIC 55 kDa subunit(gene name synonym)|uniprotkb:Transcription factor C subunit 7(gene name synonym)|uniprotkb:TFC7(gene name)|psi-mi:TFC7(display_short)|uniprotkb:YOR110W(locus name)|uniprotkb:YOR3234w(orf name)|uniprotkb:O3234(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348187|imex:IM-14275-3114 author score:98.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014663.1|sgd:S000005546|dip:DIP-1483N|mint:P38910|ensemblfungi:YOR020C(gene)|ensemblfungi:YOR020C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0042026"(protein refolding)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|interpro:IPR011032(GroES-like)|interpro:IPR018369|interpro:IPR020818|interpro:IPR037124 refseq:NP_014753.1|sgd:S000005636|mint:Q12415|dip:DIP-2309N|ensemblfungi:YOR110W(gene)|ensemblfungi:YOR110W_mRNA(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR014623(Transcription factor TFIIIC, tau55 subunit)|interpro:IPR019481|interpro:IPR029033|rcsb pdb:2YN0|rcsb pdb:6YJ6 psi-mi:"MI:0469"(intact) crc64:0453269D502C05E8 crc64:D778B81F31B83C45 figure legend:tables S3 and S4|author-confidence:98.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GVzaabkhuDg0Vb8Bdt6eXKMBE6Y559292 rogid:mn2Bb2loTD9aj7c3jHjhe3C69/8559292 intact-crc:FC6C60B4E2BE92B1|rigid:6kHyAUikxyWZcITgvmcn/i2/0VA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12415 uniprotkb:P50273 intact:EBI-33456|uniprotkb:Q07347|uniprotkb:Q6B220|uniprotkb:D6W2G9|ensemblfungi:YOR110W intact:EBI-19035|uniprotkb:D6VSY0|ensemblfungi:YDR350C psi-mi:tfc7_yeast(display_long)|uniprotkb:TFIIIC 55 kDa subunit(gene name synonym)|uniprotkb:Transcription factor C subunit 7(gene name synonym)|uniprotkb:TFC7(gene name)|psi-mi:TFC7(display_short)|uniprotkb:YOR110W(locus name)|uniprotkb:YOR3234w(orf name)|uniprotkb:O3234(orf name) psi-mi:atp22_yeast(display_long)|uniprotkb:ATP22(gene name)|psi-mi:ATP22(display_short)|uniprotkb:YDR350C(locus name)|uniprotkb:D9476.9(orf name)|uniprotkb:TCM10(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348198|imex:IM-14275-3115 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014753.1|sgd:S000005636|mint:Q12415|dip:DIP-2309N|ensemblfungi:YOR110W(gene)|ensemblfungi:YOR110W_mRNA(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR014623(Transcription factor TFIIIC, tau55 subunit)|interpro:IPR019481|interpro:IPR029033|rcsb pdb:2YN0|rcsb pdb:6YJ6 sgd:S000002758|ensemblfungi:YDR350C(gene)|ensemblfungi:YDR350C_mRNA(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0045182"(translation regulator activity)|go:"GO:0070071"(proton-transporting two-sector ATPase complex assembly)|go:"GO:0070131"(positive regulation of mitochondrial translation)|interpro:IPR017207(Mitochondrial ATPase subunit 6-specific translation factor Atp22)|refseq:NP_010637.4|dip:DIP-5246N|mint:P50273 psi-mi:"MI:0469"(intact) crc64:D778B81F31B83C45 crc64:A88992848F8F49A4 figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mn2Bb2loTD9aj7c3jHjhe3C69/8559292 rogid:gtXiP1dqs4FI3TaGDUzewbvljMA559292 intact-crc:161BB40279232690|rigid:XH0H3Y40OkVdXUf+nVN0yPQDoks false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12415 uniprotkb:Q03792 intact:EBI-33456|uniprotkb:Q07347|uniprotkb:Q6B220|uniprotkb:D6W2G9|ensemblfungi:YOR110W intact:EBI-27327|uniprotkb:D6VZX5|ensemblfungi:YMR154C psi-mi:tfc7_yeast(display_long)|uniprotkb:TFIIIC 55 kDa subunit(gene name synonym)|uniprotkb:Transcription factor C subunit 7(gene name synonym)|uniprotkb:TFC7(gene name)|psi-mi:TFC7(display_short)|uniprotkb:YOR110W(locus name)|uniprotkb:YOR3234w(orf name)|uniprotkb:O3234(orf name) psi-mi:rim13_yeast(display_long)|uniprotkb:Cysteine protease RIM13(gene name synonym)|uniprotkb:Calpain-7(gene name synonym)|uniprotkb:Regulator of IME2 protein 13(gene name synonym)|uniprotkb:CPL1(gene name synonym)|uniprotkb:YMR154C(locus name)|uniprotkb:YM8520.03C(orf name)|uniprotkb:RIM13(gene name)|psi-mi:RIM13(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348209|imex:IM-14275-3116 author score:97.40 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014753.1|sgd:S000005636|mint:Q12415|dip:DIP-2309N|ensemblfungi:YOR110W(gene)|ensemblfungi:YOR110W_mRNA(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR014623(Transcription factor TFIIIC, tau55 subunit)|interpro:IPR019481|interpro:IPR029033|rcsb pdb:2YN0|rcsb pdb:6YJ6 dip:DIP-2809N|refseq:NP_013875.1|sgd:S000004763|mint:Q03792|ensemblfungi:YMR154C(gene)|ensemblfungi:YMR154C_mRNA(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0016485"(protein processing)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR038765 psi-mi:"MI:0469"(intact) crc64:D778B81F31B83C45 - figure legend:tables S3 and S4|author-confidence:97.40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mn2Bb2loTD9aj7c3jHjhe3C69/8559292 rogid:h8qS0bcsxW/jDM52yI2FHASU/HU559292 intact-crc:FB71DC19F869220F|rigid:T+peBF5wdf6jEAFjJQ0GtUIpRSk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12434 uniprotkb:Q06451 intact:EBI-7525|uniprotkb:D6VRL3|ensemblfungi:YDL135C intact:EBI-34275|uniprotkb:D6W4F2|ensemblfungi:YPR156C psi-mi:gdir_yeast(display_long)|uniprotkb:D2175(orf name)|uniprotkb:YDL135C(locus name)|uniprotkb:RDI1(gene name)|psi-mi:RDI1(display_short) psi-mi:tpo3_yeast(display_long)|uniprotkb:TPO3(gene name)|psi-mi:TPO3(display_short)|uniprotkb:P9584.7(orf name)|uniprotkb:YPR156C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348220|imex:IM-14275-3117 author score:99.35 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010146.1|sgd:S000002294|mint:Q12434|dip:DIP-1231N|ensemblfungi:YDL135C(gene)|ensemblfungi:YDL135C_mRNA(transcript)|go:"GO:0005094"(Rho GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007015"(actin filament organization)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|interpro:IPR000406(RHO protein GDP dissociation inhibitor)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024792|reactome:R-SCE-8980692|reactome:R-SCE-9013026|reactome:R-SCE-9013148|reactome:R-SCE-9013423 refseq:NP_015482.1|sgd:S000006360|mint:Q06451|dip:DIP-3907N|ensemblfungi:YPR156C(gene)|ensemblfungi:YPR156C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 psi-mi:"MI:0469"(intact) - crc64:D260ED161F800502 figure legend:tables S3 and S4|author-confidence:99.35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:c6hedxvS0nm7P/LTsqjdfAoC49k559292 rogid:oVpx7Bjk/mK2Q7+/j05tX3gHw7k559292 intact-crc:BAC820D1696FC740|rigid:UUfrta0VMeyz/s2noDvEIEKFrbo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12443 uniprotkb:Q12443 intact:EBI-32591|uniprotkb:D6VRF0|ensemblfungi:YDL204W intact:EBI-32591|uniprotkb:D6VRF0|ensemblfungi:YDL204W psi-mi:rtn2_yeast(display_long)|uniprotkb:RTN2(gene name)|psi-mi:RTN2(display_short)|uniprotkb:D1062(orf name)|uniprotkb:YDL204W(locus name) psi-mi:rtn2_yeast(display_long)|uniprotkb:RTN2(gene name)|psi-mi:RTN2(display_short)|uniprotkb:D1062(orf name)|uniprotkb:YDL204W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348231|imex:IM-14275-3118 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010077.1|sgd:S000002363|dip:DIP-4231N|mint:Q12443|ensemblfungi:YDL204W(gene)|ensemblfungi:YDL204W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071788"(endoplasmic reticulum tubular network maintenance)|go:"GO:0071944"(cell periphery)|interpro:IPR003388(Reticulon) refseq:NP_010077.1|sgd:S000002363|dip:DIP-4231N|mint:Q12443|ensemblfungi:YDL204W(gene)|ensemblfungi:YDL204W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071788"(endoplasmic reticulum tubular network maintenance)|go:"GO:0071944"(cell periphery)|interpro:IPR003388(Reticulon) psi-mi:"MI:0469"(intact) crc64:E937E2B77759DFF5 crc64:E937E2B77759DFF5 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:jF49AeaM5t7a5TBw3/+tJ7H251g559292 rogid:jF49AeaM5t7a5TBw3/+tJ7H251g559292 intact-crc:7698F5986378FE16|rigid:9q2+qwWOjsxi/BffVhZYCYlcQAA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32793 uniprotkb:Q12446 intact:EBI-24460|uniprotkb:D3DKW1|ensemblfungi:YHR016C intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W psi-mi:ysc84_yeast(display_long)|uniprotkb:YSC84(gene name)|psi-mi:YSC84(display_short)|uniprotkb:LSB4(gene name synonym)|uniprotkb:LAS seventeen-binding protein 4(gene name synonym)|uniprotkb:YHR016C(locus name) psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348242|imex:IM-14275-3119 author score:99.26 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011880.1|sgd:S000001058|dip:DIP-2026N|mint:P32793|ensemblfungi:YHR016C(gene)|ensemblfungi:YHR016C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:2A08 refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446 psi-mi:"MI:0469"(intact) crc64:DE42E8ECF5B83C92 crc64:4488355563AA2645 figure legend:tables S3 and S4|author-confidence:99.26|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:hirm/OlqdPxvJNPbha68BSFIvmQ559292 rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292 intact-crc:1599685ED1FF7927|rigid:z2MQ/HuooxRCmp21eiCnGOhPR0I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12446 uniprotkb:P33204 intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W intact:EBI-2757|uniprotkb:D6VXS3|ensemblfungi:YKL013C psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name) psi-mi:arpc4_yeast(display_long)|uniprotkb:ARC19(gene name)|psi-mi:ARC19(display_short)|uniprotkb:YKL013C(locus name)|uniprotkb:YKL166(orf name)|uniprotkb:Arp2/3 complex 20 kDa(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348253|imex:IM-14275-3120 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446 refseq:NP_012912.1|sgd:S000001496|dip:DIP-1819N|mint:P33204|ensemblfungi:YKL013C(gene)|ensemblfungi:YKL013C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:4488355563AA2645 crc64:B80CBD6642E39C1C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292 rogid:wscMsqBK/3Rsah+2vbE3REyYhhg559292 intact-crc:BE59C140C2D34991|rigid:Ioti7upMZ4xJkMWkCnA3blhSK9A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12446 uniprotkb:P37370 intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name) psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348264|imex:IM-14275-3121 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446 refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370 psi-mi:"MI:0469"(intact) crc64:4488355563AA2645 crc64:24C7522D5B1CA1C8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 intact-crc:4F6A1DD62803EBDC|rigid:bAf9x93U4M05M4QEALXeNq/9ng4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12446 uniprotkb:P38328 intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W intact:EBI-2777|uniprotkb:D6VQN0|ensemblfungi:YBR234C psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name) psi-mi:arpc1_yeast(display_long)|uniprotkb:ARC40(gene name)|psi-mi:ARC40(display_short)|uniprotkb:YBR234C(locus name)|uniprotkb:YBR1532(orf name)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348275|imex:IM-14275-3122 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446 sgd:S000000438|refseq:NP_009793.1|dip:DIP-2219N|mint:P38328|ensemblfungi:YBR234C(gene)|ensemblfungi:YBR234C_mRNA(transcript)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:4488355563AA2645 crc64:D75C6BB8EC35EEDF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292 rogid:SDFaDFaJRhwZT02o7w/XmITMZgI559292 intact-crc:CB80EADCD5878CEC|rigid:qhOnCkUkFsuIGfDKBhmq+qvzrlo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12446 uniprotkb:P39013 intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W intact:EBI-6460|intact:EBI-33854|intact:EBI-30557|intact:EBI-31021|uniprotkb:D6W195|uniprotkb:Q8TFC4|uniprotkb:Q8TFD0|uniprotkb:Q8TG51|ensemblfungi:YNL084C psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name) psi-mi:end3_yeast(display_long)|uniprotkb:END3(gene name)|psi-mi:END3(display_short)|uniprotkb:YNL084C(locus name)|uniprotkb:N2307(orf name)|uniprotkb:Endocytosis protein 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348286|imex:IM-14275-3123 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446 refseq:NP_014315.1|sgd:S000005028|mint:P39013|dip:DIP-2220N|ensemblfungi:YNL084C(gene)|ensemblfungi:YNL084C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0071944"(cell periphery)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR025604|reactome:R-SCE-416482|reactome:R-SCE-8856828|reactome:R-SCE-9013148|reactome:R-SCE-9013406 psi-mi:"MI:0469"(intact) crc64:4488355563AA2645 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292 rogid:AvVFZdzX/4DkLet/+FGA8KrKfCw559292 intact-crc:DFECA695F40BAFA5|rigid:hr/WtmVH4QqPiHxR7wDBf7/5d5U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40518 uniprotkb:Q12446 intact:EBI-2750|uniprotkb:D6VVM2|ensemblfungi:YIL062C intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W psi-mi:arpc5_yeast(display_long)|uniprotkb:ARC15(gene name)|psi-mi:ARC15(display_short)|uniprotkb:Arp2/3 complex 16 kDa subunit(gene name synonym)|uniprotkb:YIL062C(locus name) psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348297|imex:IM-14275-3124 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012202.1|sgd:S000001324|dip:DIP-2101N|mint:P40518|ensemblfungi:YIL062C(gene)|ensemblfungi:YIL062C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR036743|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-6798695|reactome:R-SCE-8856828 refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446 psi-mi:"MI:0469"(intact) crc64:10E4DAF0F0801B02 crc64:4488355563AA2645 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:iQ0mLisINMjXPulrRyDmrLcdpzU559292 rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292 intact-crc:9D862F58FF5BACA5|rigid:yUAPKT60Nwf1pMw4OCd51YAMix4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43603 uniprotkb:Q12446 intact:EBI-22980|uniprotkb:D6VTQ4|ensemblfungi:YFR024C-A intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W psi-mi:lsb3_yeast(display_long)|uniprotkb:LSB3(gene name)|psi-mi:LSB3(display_short)|uniprotkb:YFR024C(orf name)|uniprotkb:YFR024C-A(locus name) psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348308|imex:IM-14275-3125 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002968|refseq:NP_219497.4|dip:DIP-6259N|mint:P43603|ensemblfungi:YFR024C-A(gene)|ensemblfungi:YFR024C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:1OOT|rcsb pdb:1SSH refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446 psi-mi:"MI:0469"(intact) crc64:F486C787B5771AAC crc64:4488355563AA2645 figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zKMZQRpG4d/at/NecQDyEi/kVKg559292 rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292 intact-crc:CCD5B873DF8D75A6|rigid:EkIzfQZjc6DexCh4Oo8UFk35ocE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12446 uniprotkb:Q04439 intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W intact:EBI-11687|ensemblfungi:YMR109W|uniprotkb:D6VZT2 psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name) psi-mi:myo5_yeast(display_long)|uniprotkb:MYO5(gene name)|psi-mi:MYO5(display_short)|uniprotkb:YMR109W(locus name)|uniprotkb:YM9718.08(orf name)|uniprotkb:Class I unconventional myosin MYO5(gene name synonym)|uniprotkb:Type I myosin MYO5(gene name synonym)|uniprotkb:Actin-dependent myosin-I MYO5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348319|imex:IM-14275-3126 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446 ensemblfungi:YMR109W_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0009651"(response to salt stress)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051286"(cell tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071944"(cell periphery)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035535|ensemblfungi:YMR109W(gene)|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|rcsb pdb:1YP5|rcsb pdb:1ZUY|refseq:NP_013827.1|sgd:S000004715|mint:Q04439|dip:DIP-2222N psi-mi:"MI:0469"(intact) crc64:4488355563AA2645 crc64:DFFB9EC16B61CD29 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292 rogid:n/Po/L9Xd7LP+fY39QaqP/s5US4559292 intact-crc:9398B59B203D6849|rigid:k8MpNHdkBItzyIc/PsT/Al6t7Nc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12446 uniprotkb:Q05933 intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W intact:EBI-2764|uniprotkb:D6VZ07|ensemblfungi:YLR370C psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name) psi-mi:arpc3_yeast(display_long)|uniprotkb:ARC18(gene name)|psi-mi:ARC18(display_short)|uniprotkb:YLR370C(locus name)|uniprotkb:L8039.15(orf name)|uniprotkb:Arp2/3 complex 21 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348330|imex:IM-14275-3127 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446 sgd:S000004362|refseq:NP_013474.3|dip:DIP-2218N|mint:Q05933|ensemblfungi:YLR370C(gene)|ensemblfungi:YLR370C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR007204(ARP2/3 complex, 21 kDa p21-Arc subunit)|interpro:IPR036753|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-8856828 psi-mi:"MI:0469"(intact) crc64:4488355563AA2645 crc64:456EABC2B9CC4860 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292 rogid:Fj4cwULcw1TK5uS1lJczcNc5gns559292 intact-crc:F64FB7D6B1313D33|rigid:4l3+nafPNSc2jqoqS9IWt8viVvg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12446 uniprotkb:Q12446 intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name) psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348341|imex:IM-14275-3128 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446 refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446 psi-mi:"MI:0469"(intact) crc64:4488355563AA2645 crc64:4488355563AA2645 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292 rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292 intact-crc:42C5D23099C2205B|rigid:zgMPXfJAGgovexrgd9z7EZcZEZc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12447 uniprotkb:P34221 intact:EBI-33397|uniprotkb:D6VS57|ensemblfungi:YDR071C intact:EBI-12805|uniprotkb:Q92330|uniprotkb:D6VPU4|ensemblfungi:YBL056W psi-mi:paa1_yeast(display_long)|uniprotkb:Arylalkylamine N-acetyltransferase homolog(gene name synonym)|uniprotkb:YDR071C(locus name)|uniprotkb:PAA1(gene name)|psi-mi:PAA1(display_short) psi-mi:pp2c3_yeast(display_long)|uniprotkb:PTC3(gene name)|psi-mi:PTC3(display_short)|uniprotkb:YBL0511(orf name)|uniprotkb:YBL0513(orf name)|uniprotkb:YBL056W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348352|imex:IM-14275-3129 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002478|refseq:NP_010356.1|mint:Q12447|dip:DIP-1540N|ensemblfungi:YDR071C(gene)|ensemblfungi:YDR071C_mRNA(transcript)|go:"GO:0004059"(aralkylamine N-acetyltransferase activity)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|reactome:R-SCE-209931 ensemblfungi:YBL056W(gene)|ensemblfungi:YBL056W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C, manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|refseq:NP_009497.2|sgd:S000000152|mint:P34221|dip:DIP-3944N psi-mi:"MI:0469"(intact) crc64:76AAC4EA2926660D crc64:70AC2707C7FA2122 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:yE2a9WbQI7PPmhpVcKh7Z//yMjw559292 rogid:igOpqJjHW4B7yBbADsYfaKaX/3M559292 intact-crc:ABDA4657A6C2028D|rigid:J6P3mCbza/anv2bN5CV8lTiNiz0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38353 uniprotkb:Q12450 intact:EBI-18175|uniprotkb:D6VQS8|ensemblfungi:YBR283C intact:EBI-6598|uniprotkb:D6W282|ensemblfungi:YOR016C psi-mi:ssh1_yeast(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:Ssh1 complex subunit alpha(gene name synonym)|uniprotkb:Ssh1 complex subunit SSH1(gene name synonym)|uniprotkb:YBR2020(orf name)|uniprotkb:YBR283C(locus name) psi-mi:erp4_yeast(display_long)|uniprotkb:ERP4(gene name)|psi-mi:ERP4(display_short)|uniprotkb:YOR016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348363|imex:IM-14275-3130 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009842.1|sgd:S000000487|ensemblfungi:YBR283C(gene)|ensemblfungi:YBR283C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:2WW9|rcsb pdb:2WWA|dip:DIP-4962N|mint:P38353 refseq:NP_014659.1|sgd:S000005542|mint:Q12450|dip:DIP-7868N|ensemblfungi:YOR016C(gene)|ensemblfungi:YOR016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) crc64:48267EEA3E0191BD - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:76wvZIdv7W5BQn6wI+sHOGQAyuc559292 rogid:An7as6LjEDUYrLvEbua3xSL6bEk559292 intact-crc:2C6E692B1CEFBB57|rigid:KCwGtA9gEXNlAqFrathLsaUrWiU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53198 uniprotkb:Q12450 intact:EBI-2058104|uniprotkb:D6VUD6|uniprotkb:E9P916|ensemblfungi:YGL002W intact:EBI-6598|uniprotkb:D6W282|ensemblfungi:YOR016C psi-mi:erp6_yeast(display_long)|uniprotkb:ERP6(gene name)|psi-mi:ERP6(display_short)|uniprotkb:YGL002W(locus name) psi-mi:erp4_yeast(display_long)|uniprotkb:ERP4(gene name)|psi-mi:ERP4(display_short)|uniprotkb:YOR016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348374|imex:IM-14275-3131 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011513.1|sgd:S000002970|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:P53198|ensemblfungi:YGL002W(gene)|ensemblfungi:YGL002W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|reactome:R-SCE-6811434 refseq:NP_014659.1|sgd:S000005542|mint:Q12450|dip:DIP-7868N|ensemblfungi:YOR016C(gene)|ensemblfungi:YOR016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:pM23btPgVfhIqmxeV0jxQGSX4/8559292 rogid:An7as6LjEDUYrLvEbua3xSL6bEk559292 intact-crc:A444E7CB41BEA9E6|rigid:GI/i+niuRzSysqtG2Boab+Y30L0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53337 uniprotkb:Q12450 intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C intact:EBI-6598|uniprotkb:D6W282|ensemblfungi:YOR016C psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:erp4_yeast(display_long)|uniprotkb:ERP4(gene name)|psi-mi:ERP4(display_short)|uniprotkb:YOR016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348385|imex:IM-14275-3132 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 refseq:NP_014659.1|sgd:S000005542|mint:Q12450|dip:DIP-7868N|ensemblfungi:YOR016C(gene)|ensemblfungi:YOR016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 rogid:An7as6LjEDUYrLvEbua3xSL6bEk559292 intact-crc:435025F1B486E739|rigid:BiSt65AWgN5pCVktH6D5gAX0VnE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:Q12450 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-6598|uniprotkb:D6W282|ensemblfungi:YOR016C psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:erp4_yeast(display_long)|uniprotkb:ERP4(gene name)|psi-mi:ERP4(display_short)|uniprotkb:YOR016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348396|imex:IM-14275-3133 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_014659.1|sgd:S000005542|mint:Q12450|dip:DIP-7868N|ensemblfungi:YOR016C(gene)|ensemblfungi:YOR016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:An7as6LjEDUYrLvEbua3xSL6bEk559292 intact-crc:46E202D6B4AED44D|rigid:ebfCwQmyJucHNsGqydaflWWbVE4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:Q12450 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-6598|uniprotkb:D6W282|ensemblfungi:YOR016C psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:erp4_yeast(display_long)|uniprotkb:ERP4(gene name)|psi-mi:ERP4(display_short)|uniprotkb:YOR016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348407|imex:IM-14275-3134 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_014659.1|sgd:S000005542|mint:Q12450|dip:DIP-7868N|ensemblfungi:YOR016C(gene)|ensemblfungi:YOR016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|reactome:R-SCE-6811434 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:An7as6LjEDUYrLvEbua3xSL6bEk559292 intact-crc:E565FE25C1B17A6D|rigid:BG6cJwNGV5kWmW1jjq3rQO9Ici8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12450 uniprotkb:Q06144 intact:EBI-6598|uniprotkb:D6W282|ensemblfungi:YOR016C intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:erp4_yeast(display_long)|uniprotkb:ERP4(gene name)|psi-mi:ERP4(display_short)|uniprotkb:YOR016C(locus name) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348418|imex:IM-14275-3135 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014659.1|sgd:S000005542|mint:Q12450|dip:DIP-7868N|ensemblfungi:YOR016C(gene)|ensemblfungi:YOR016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|reactome:R-SCE-6811434 refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695 psi-mi:"MI:0469"(intact) - crc64:2F474503CAB7C195 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:An7as6LjEDUYrLvEbua3xSL6bEk559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 intact-crc:7CD90DB566564F9B|rigid:lM5wrpgWllOgsrd+qjcCDBl48Bw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12451 uniprotkb:Q03010 intact:EBI-12621|uniprotkb:P89891|uniprotkb:D6VRX1|ensemblfungi:YDL019C intact:EBI-20070|uniprotkb:P87330|uniprotkb:D6W3M9|ensemblfungi:YPL139C psi-mi:osh2_yeast(display_long)|uniprotkb:D2845(orf name)|uniprotkb:YDL019C(locus name)|uniprotkb:OSH2(gene name)|psi-mi:OSH2(display_short) psi-mi:ume1_yeast(display_long)|uniprotkb:UME1(gene name)|psi-mi:UME1(display_short)|uniprotkb:WTM3(gene name synonym)|uniprotkb:YPL139C(locus name)|uniprotkb:LPI7C(orf name)|uniprotkb:WD repeat-containing transcriptional modulator 3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348429|imex:IM-14275-3136 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDL019C(gene)|ensemblfungi:YDL019C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035621"(ER to Golgi ceramide transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071944"(cell periphery)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR036770|interpro:IPR037239|reactome:R-SCE-192105|go:"GO:0120015"(sterol transfer activity)|refseq:NP_010265.1|sgd:S000002177|mint:Q12451|dip:DIP-6712N refseq:NP_015186.1|sgd:S000006060|ensemblfungi:YPL139C(gene)|ensemblfungi:YPL139C_mRNA(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070210"(Rpd3L-Expanded complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR036322|reactome:R-SCE-3214815|reactome:R-SCE-3214847|reactome:R-SCE-3214858|dip:DIP-5290N|mint:Q03010 psi-mi:"MI:0469"(intact) crc64:D521957460E7F7C3 crc64:AA6F60448B7BCBA9 figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:75/WAoxCRsenLJMmbyowdFQ8srs559292 rogid:radf8gBaPrKRK281JuKAYZprO34559292 intact-crc:8169F214A828440F|rigid:uwvFsgSYMlHnicZUMt9X1YiJ1/0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04439 uniprotkb:Q12451 intact:EBI-11687|ensemblfungi:YMR109W|uniprotkb:D6VZT2 intact:EBI-12621|uniprotkb:P89891|uniprotkb:D6VRX1|ensemblfungi:YDL019C psi-mi:myo5_yeast(display_long)|uniprotkb:MYO5(gene name)|psi-mi:MYO5(display_short)|uniprotkb:YMR109W(locus name)|uniprotkb:YM9718.08(orf name)|uniprotkb:Class I unconventional myosin MYO5(gene name synonym)|uniprotkb:Type I myosin MYO5(gene name synonym)|uniprotkb:Actin-dependent myosin-I MYO5(gene name synonym) psi-mi:osh2_yeast(display_long)|uniprotkb:D2845(orf name)|uniprotkb:YDL019C(locus name)|uniprotkb:OSH2(gene name)|psi-mi:OSH2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348440|imex:IM-14275-3137 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR109W_mRNA(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0009651"(response to salt stress)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051286"(cell tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071944"(cell periphery)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035535|ensemblfungi:YMR109W(gene)|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|rcsb pdb:1YP5|rcsb pdb:1ZUY|refseq:NP_013827.1|sgd:S000004715|mint:Q04439|dip:DIP-2222N ensemblfungi:YDL019C(gene)|ensemblfungi:YDL019C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035621"(ER to Golgi ceramide transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071944"(cell periphery)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR036770|interpro:IPR037239|reactome:R-SCE-192105|go:"GO:0120015"(sterol transfer activity)|refseq:NP_010265.1|sgd:S000002177|mint:Q12451|dip:DIP-6712N psi-mi:"MI:0469"(intact) crc64:DFFB9EC16B61CD29 crc64:D521957460E7F7C3 figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:n/Po/L9Xd7LP+fY39QaqP/s5US4559292 rogid:75/WAoxCRsenLJMmbyowdFQ8srs559292 intact-crc:5CEB5972FE6507B9|rigid:5zuzpmfQxtq7zcAVw6MyVqqhY3I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12452 uniprotkb:P14359 intact:EBI-38132|uniprotkb:D6VYA1|ensemblfungi:YLR100W intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:erg27_yeast(display_long)|uniprotkb:ERG27(gene name)|psi-mi:ERG27(display_short)|uniprotkb:YLR100W(locus name) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348451|imex:IM-14275-3138 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013201.1|sgd:S000004090|mint:Q12452|dip:DIP-1237N|ensemblfungi:YLR100W(gene)|ensemblfungi:YLR100W_mRNA(transcript)|go:"GO:0000253"(3-keto sterol reductase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006696"(ergosterol biosynthetic process)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|interpro:IPR038765|interpro:IPR042829 refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD psi-mi:"MI:0469"(intact) crc64:D9A0589C049D8C49 crc64:DBA26AF5B769C02A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:O7stXbO9C0tvqJH/yjFPDMjib64559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 intact-crc:DE6B44190438C27D|rigid:AV+FAbH840pw57m6pt3sj9KrKJ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12452 uniprotkb:P38225 intact:EBI-38132|uniprotkb:D6VYA1|ensemblfungi:YLR100W intact:EBI-6819|uniprotkb:O60021|uniprotkb:Q86ZS3|uniprotkb:D6VQ41|ensemblfungi:YBR041W psi-mi:erg27_yeast(display_long)|uniprotkb:ERG27(gene name)|psi-mi:ERG27(display_short)|uniprotkb:YLR100W(locus name) psi-mi:fat1_yeast(display_long)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:Very-long-chain acyl-CoA synthetase(gene name synonym)|uniprotkb:YBR0411(orf name)|uniprotkb:YBR041W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348462|imex:IM-14275-3139 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013201.1|sgd:S000004090|mint:Q12452|dip:DIP-1237N|ensemblfungi:YLR100W(gene)|ensemblfungi:YLR100W_mRNA(transcript)|go:"GO:0000253"(3-keto sterol reductase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006696"(ergosterol biosynthetic process)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|interpro:IPR038765|interpro:IPR042829 refseq:NP_009597.2|sgd:S000000245|mint:P38225|dip:DIP-5048N|ensemblfungi:YBR041W(gene)|ensemblfungi:YBR041W_mRNA(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0071944"(cell periphery)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR030310|interpro:IPR042099|reactome:R-SCE-159418|reactome:R-SCE-193368|reactome:R-SCE-193775|reactome:R-SCE-389599|reactome:R-SCE-6798695|reactome:R-SCE-804914|reactome:R-SCE-9033241 psi-mi:"MI:0469"(intact) crc64:D9A0589C049D8C49 crc64:509A5DEDDEE98823 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:O7stXbO9C0tvqJH/yjFPDMjib64559292 rogid:mGjvEcQ/ZVHp/P+89KaQ7DrjcQg559292 intact-crc:D7D41E7CC72487C2|rigid:5hj2E2EUW3PRWeKbfKmlgv/o/cs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12452 uniprotkb:P38604 intact:EBI-38132|uniprotkb:D6VYA1|ensemblfungi:YLR100W intact:EBI-6572|uniprotkb:Q92327|uniprotkb:D3DL21|ensemblfungi:YHR072W psi-mi:erg27_yeast(display_long)|uniprotkb:ERG27(gene name)|psi-mi:ERG27(display_short)|uniprotkb:YLR100W(locus name) psi-mi:erg7_yeast(display_long)|uniprotkb:Oxidosqualene--lanosterol cyclase(gene name synonym)|uniprotkb:2,3-epoxysqualene--lanosterol cyclase(gene name synonym)|uniprotkb:YHR072W(locus name)|uniprotkb:ERG7(gene name)|psi-mi:ERG7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348473|imex:IM-14275-3140 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013201.1|sgd:S000004090|mint:Q12452|dip:DIP-1237N|ensemblfungi:YLR100W(gene)|ensemblfungi:YLR100W_mRNA(transcript)|go:"GO:0000253"(3-keto sterol reductase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006696"(ergosterol biosynthetic process)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|interpro:IPR038765|interpro:IPR042829 refseq:NP_011939.2|sgd:S000001114|mint:P38604|dip:DIP-8319N|ensemblfungi:YHR072W(gene)|ensemblfungi:YHR072W_mRNA(transcript)|go:"GO:0000250"(lanosterol synthase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016104"(triterpenoid biosynthetic process)|go:"GO:0042300"(beta-amyrin synthase activity)|interpro:IPR002365(Terpene synthase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR018333|interpro:IPR032696|interpro:IPR032697|reactome:R-SCE-191273 psi-mi:"MI:0469"(intact) crc64:D9A0589C049D8C49 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:O7stXbO9C0tvqJH/yjFPDMjib64559292 rogid:zqDPA3GvKWkMTmH97TcdF8HOHBU559292 intact-crc:53AB9A7873351956|rigid:u3jQw0fgpffjVkoSOnsaZ3zvISM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12452 uniprotkb:Q07804 intact:EBI-38132|uniprotkb:D6VYA1|ensemblfungi:YLR100W intact:EBI-36254|uniprotkb:D6VXZ0|ensemblfungi:YLL012W psi-mi:erg27_yeast(display_long)|uniprotkb:ERG27(gene name)|psi-mi:ERG27(display_short)|uniprotkb:YLR100W(locus name) psi-mi:yeh1_yeast(display_long)|uniprotkb:Steryl ester hydrolase 1(gene name synonym)|uniprotkb:YEH1(gene name)|psi-mi:YEH1(display_short)|uniprotkb:YLL012W(locus name)|uniprotkb:L1329(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348484|imex:IM-14275-3141 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013201.1|sgd:S000004090|mint:Q12452|dip:DIP-1237N|ensemblfungi:YLR100W(gene)|ensemblfungi:YLR100W_mRNA(transcript)|go:"GO:0000253"(3-keto sterol reductase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006696"(ergosterol biosynthetic process)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|interpro:IPR038765|interpro:IPR042829 refseq:NP_013089.1|sgd:S000003935|mint:Q07804|dip:DIP-4156N|ensemblfungi:YLL012W(gene)|ensemblfungi:YLL012W_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016125"(sterol metabolic process)|interpro:IPR006693(AB-hydrolase associated lipase region)|interpro:IPR029058|reactome:R-SCE-192456|reactome:R-SCE-6809371 psi-mi:"MI:0469"(intact) crc64:D9A0589C049D8C49 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:O7stXbO9C0tvqJH/yjFPDMjib64559292 rogid:Fv+RBBi6c7i++sW0AISZDXDrlrI559292 intact-crc:CA459D983F6A475B|rigid:eX7z96Oi7l20YMOrIcv51O0X7m4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12168 uniprotkb:Q12452 intact:EBI-32973|uniprotkb:Q07268|uniprotkb:D6VYD8|ensemblfungi:YLR144C intact:EBI-38132|uniprotkb:D6VYA1|ensemblfungi:YLR100W psi-mi:eng2_yeast(display_long)|uniprotkb:ACF2(gene name)|psi-mi:ACF2(display_short)|uniprotkb:YLR144C(locus name)|uniprotkb:Laminarinase-2(gene name synonym)|uniprotkb:ENG2(gene name synonym)|uniprotkb:PCA1(gene name synonym)|uniprotkb:L3180(orf name) psi-mi:erg27_yeast(display_long)|uniprotkb:ERG27(gene name)|psi-mi:ERG27(display_short)|uniprotkb:YLR100W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348495|imex:IM-14275-3142 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013245.1|sgd:S000004134|mint:Q12168|dip:DIP-2889N|ensemblfungi:YLR144C(gene)|ensemblfungi:YLR144C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042973"(glucan endo-1,3-beta-D-glucosidase activity)|go:"GO:0052861"(glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group)|go:"GO:0052862"(glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group)|interpro:IPR005200(Glycoside hydrolase, family 81)|interpro:IPR040451|interpro:IPR040720 refseq:NP_013201.1|sgd:S000004090|mint:Q12452|dip:DIP-1237N|ensemblfungi:YLR100W(gene)|ensemblfungi:YLR100W_mRNA(transcript)|go:"GO:0000253"(3-keto sterol reductase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006696"(ergosterol biosynthetic process)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|interpro:IPR038765|interpro:IPR042829 psi-mi:"MI:0469"(intact) - crc64:D9A0589C049D8C49 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:8STCUe6Ie2CnTTBMjY8wrld5h44559292 rogid:O7stXbO9C0tvqJH/yjFPDMjib64559292 intact-crc:592F58A55BEEB1EB|rigid:TEGhExPjWE0EN4yUbAZMC5RMxew false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:Q12462 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348506|imex:IM-14275-3143 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438 refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) psi-mi:"MI:0469"(intact) crc64:796859026AC63CC0 - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 intact-crc:B570FDBBBE81F7B3|rigid:Ozi1sG1fF+BBgr4Wx8gAEM+Usbw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12462 uniprotkb:P22289 intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C intact:EBI-19947|uniprotkb:D6VUW6|ensemblfungi:YGR183C psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:qcr9_yeast(display_long)|uniprotkb:QCR9(gene name)|psi-mi:QCR9(display_short)|uniprotkb:Ubiquinol-cytochrome c oxidoreductase subunit 9(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c reductase 7.3 kDa protein(gene name synonym)|uniprotkb:YGR183C(locus name)|uniprotkb:Cytochrome c1 non-heme 7.3 kDa protein(gene name synonym)|uniprotkb:Complex III subunit X(gene name synonym)|uniprotkb:Complex III subunit 9(gene name synonym)|uniprotkb:UCR9(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348517|imex:IM-14275-3144 author score:99.32 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) interpro:IPR036656|refseq:NP_011699.1|sgd:S000003415|interpro:IPR008027(Ubiquinol-cytochrome C reductase, UQCRX/QCR9-like)|ensemblfungi:YGR183C(gene)|ensemblfungi:YGR183C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0009060"(aerobic respiration)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:1902600"(proton transmembrane transport)|rcsb pdb:1EZV|rcsb pdb:1KB9|rcsb pdb:1KYO|rcsb pdb:1P84|rcsb pdb:2IBZ|rcsb pdb:3CX5|rcsb pdb:3CXH|rcsb pdb:4PD4|rcsb pdb:6GIQ|rcsb pdb:6HU9|rcsb pdb:6T0B|rcsb pdb:6T15|reactome:R-SCE-611105|mint:P22289 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.32|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 rogid:C2Sa3lOqiMzEpx/H0AdOUS3mEYk559292 intact-crc:564AECA3FEF12B5F|rigid:Vp5yUm5NtkB50URGIrQqlTpykVU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12462 uniprotkb:P23542 intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C intact:EBI-2002|uniprotkb:D6VY29|ensemblfungi:YLR027C psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:aatc_yeast(display_long)|uniprotkb:AAT2(gene name)|psi-mi:AAT2(display_short)|uniprotkb:YLR027C(locus name)|uniprotkb:ASP5(gene name synonym)|uniprotkb:L1746(orf name)|uniprotkb:Transaminase A(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348528|imex:IM-14275-3145 author score:97.60 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) refseq:NP_013127.2|sgd:S000004017|dip:DIP-2897N|mint:P23542|go:"GO:0019266"(asparagine biosynthetic process from oxaloacetate)|go:"GO:0030170"(pyridoxal phosphate binding)|interpro:IPR000796(Aspartate/other aminotransferase)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:1YAA|reactome:R-SCE-70263|reactome:R-SCE-8963693|ensemblfungi:YLR027C(gene)|ensemblfungi:YLR027C_mRNA(transcript)|go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0006532"(aspartate biosynthetic process)|go:"GO:0006536"(glutamate metabolic process) psi-mi:"MI:0469"(intact) - crc64:D25F40F6C6DD2B33 figure legend:tables S3 and S4|author-confidence:97.60|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 rogid:eNypS723YWwMMuWVVoTnidvQuaA559292 intact-crc:BEB7439AED965DFB|rigid:1AYd/fGD+ggUINiIjvpofGz2Sn0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12462 uniprotkb:P28795 intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C intact:EBI-13164|uniprotkb:D6VSW1|ensemblfungi:YDR329C psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:pex3_yeast(display_long)|uniprotkb:PEX3(gene name)|psi-mi:PEX3(display_short)|uniprotkb:PAS3(gene name synonym)|uniprotkb:YDR329C(locus name)|uniprotkb:D9798.15(orf name)|uniprotkb:Peroxin-3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348539|imex:IM-14275-3146 author score:89.63 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) sgd:S000002737|refseq:NP_010616.3|mint:P28795|dip:DIP-2477N|ensemblfungi:YDR329C(gene)|ensemblfungi:YDR329C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0045033"(peroxisome inheritance)|go:"GO:0045046"(protein import into peroxisome membrane)|interpro:IPR006966(Peroxin-3)|reactome:R-SCE-1369062|reactome:R-SCE-9603798 psi-mi:"MI:0469"(intact) - crc64:3CDC1D036DF0D0F9 figure legend:tables S3 and S4|author-confidence:89.63|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 rogid:YcXHJijTXVH0oLXYmqsvIT/OeV4559292 intact-crc:84721B2EE47125D1|rigid:zihClotj9bzsjHB/40lAMQy18Bo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12462 uniprotkb:P33327 intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C intact:EBI-5815|ensemblfungi:YDL215C|uniprotkb:D6VRD9 psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:dhe2_yeast(display_long)|uniprotkb:YDL215C(locus name)|uniprotkb:GDH2(gene name)|psi-mi:GDH2(display_short)|uniprotkb:D0892(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348550|imex:IM-14275-3147 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) ensemblfungi:YDL215C(gene)|ensemblfungi:YDL215C_mRNA(transcript)|go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0019551"(glutamate catabolic process to 2-oxoglutarate)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR016210(Glutamate dehydrogenase, NAD-dependent)|interpro:IPR033524|interpro:IPR036291|refseq:NP_010066.1|sgd:S000002374|dip:DIP-1689N|mint:P33327 psi-mi:"MI:0469"(intact) - crc64:DF8358D831E4545F figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 rogid:bjvKAO4gyrNUq2Wwq3Y+FvEv7RM559292 intact-crc:E1227DA3D7BD3EF1|rigid:uulGyEvHrGWI2MO4T8zODO5mg6U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40582 uniprotkb:Q12462 intact:EBI-7941|uniprotkb:D6VVW9|ensemblfungi:YIR038C intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C psi-mi:gst1_yeast(display_long)|uniprotkb:YIR038C(locus name)|uniprotkb:GTT1(gene name)|psi-mi:GTT1(display_short)|uniprotkb:GST-I(gene name synonym) psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348561|imex:IM-14275-3148 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012304.1|sgd:S000001477|mint:P40582|dip:DIP-2103N|ensemblfungi:YIR038C(gene)|ensemblfungi:YIR038C_mRNA(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010731"(protein glutathionylation)|go:"GO:0071944"(cell periphery)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079 refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) psi-mi:"MI:0469"(intact) crc64:3C07D40D29F60DFF - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+bqzHpsoLw4j2qQBzHbkfldR5OU559292 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 intact-crc:AFB471FA94A87A84|rigid:AeZhftfEixibu+YUSrtVvupDjqM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40994 uniprotkb:Q12462 intact:EBI-2824|uniprotkb:D6W2F5|ensemblfungi:YOR094W intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C psi-mi:arf3_yeast(display_long)|uniprotkb:ARF3(gene name)|psi-mi:ARF3(display_short)|uniprotkb:YOR3172W(orf name)|uniprotkb:YOR094W(locus name) psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348572|imex:IM-14275-3149 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014737.1|sgd:S000005620|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P40994|interpro:IPR041838|ensemblfungi:YOR094W(gene)|ensemblfungi:YOR094W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010513"(positive regulation of phosphatidylinositol biosynthetic process)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0036267"(invasive filamentous growth)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization) refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:uC+fupPUZajD7m7pLEO/K0Kuudo559292 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 intact-crc:2A13FDE11F374CBA|rigid:3NP238NFpajqqBShZQdYf/5Hm0s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53112 uniprotkb:Q12462 intact:EBI-13212|uniprotkb:D6VTZ8|ensemblfungi:YGL153W intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C psi-mi:pex14_yeast(display_long)|uniprotkb:PEX14(gene name)|psi-mi:PEX14(display_short)|uniprotkb:YGL153W(locus name)|uniprotkb:G1870(orf name)|uniprotkb:Peroxin-14(gene name synonym) psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348583|imex:IM-14275-3150 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003121|refseq:NP_011362.3|mint:P53112|dip:DIP-1749N|ensemblfungi:YGL153W(gene)|ensemblfungi:YGL153W_mRNA(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:1990415"|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR006785(Peroxisome membrane anchor protein Pex14p, N-terminal)|interpro:IPR025655|interpro:IPR036388|rcsb pdb:1N5Z|rcsb pdb:2V1R|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-9603798 refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) psi-mi:"MI:0469"(intact) crc64:B714D7DA045E2DCB - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:eS7O3dwiT/56U30PI8bpJny+kZQ559292 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 intact-crc:A9DE3AB6D4EC37FB|rigid:h7tX1GWYYqEprRiAEF+5TzOPZy8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P80667 uniprotkb:Q12462 intact:EBI-13206|ensemblfungi:YLR191W|uniprotkb:D6VYJ4 intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C psi-mi:pex13_yeast(display_long)|uniprotkb:PEX13(gene name)|psi-mi:PEX13(display_short)|uniprotkb:PAS20(gene name synonym)|uniprotkb:YLR191W(locus name)|uniprotkb:L9470.1(orf name)|uniprotkb:Peroxin-13(gene name synonym) psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348594|imex:IM-14275-3151 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013292.1|sgd:S000004181|ensemblfungi:YLR191W(gene)|ensemblfungi:YLR191W_mRNA(transcript)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:1990415"|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|interpro:IPR035463|interpro:IPR036028|rcsb pdb:1JQQ|rcsb pdb:1N5Z|rcsb pdb:1NM7|rcsb pdb:2V1R|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-9603798|mint:P80667|dip:DIP-2473N refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) psi-mi:"MI:0469"(intact) crc64:DBEA9A2372185860 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vt02VeRiVrVNk3HkjG1GPEcvPSU559292 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 intact-crc:92D3DE2A6E5E9DE0|rigid:gWw9M2+zH/Kmt0dEPknf0hcuUtI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12462 uniprotkb:Q02969 intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C intact:EBI-37452|uniprotkb:Q6B2A9|uniprotkb:D6W3Q5|ensemblfungi:YPL112C psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:pex25_yeast(display_long)|uniprotkb:YPL112C(locus name)|uniprotkb:PEX25(gene name)|psi-mi:PEX25(display_short)|uniprotkb:Peroxin-25(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348605|imex:IM-14275-3152 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) sgd:S000006033|refseq:NP_015213.1|dip:DIP-5292N|mint:Q02969|ensemblfungi:YPL112C(gene)|ensemblfungi:YPL112C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016559"(peroxisome fission)|go:"GO:0044375"(regulation of peroxisome size)|interpro:IPR008733(Peroxisomal biogenesis factor 11) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 rogid:42Jce4KR0S5WehK1GVfqhG+Cqbo559292 intact-crc:83096553EDDCDE83|rigid:ubKdc5UTOGw0xiOa+L9NMfVWuQA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06497 uniprotkb:Q12462 intact:EBI-36879|uniprotkb:D6W4C5|ensemblfungi:YPR128C intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C psi-mi:ant1_yeast(display_long)|uniprotkb:ANT1(gene name)|psi-mi:ANT1(display_short)|uniprotkb:YPR128C(locus name) psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348616|imex:IM-14275-3153 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015453.1|sgd:S000006332|mint:Q06497|dip:DIP-8825N|ensemblfungi:YPR128C(gene)|ensemblfungi:YPR128C_mRNA(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0005347"(ATP transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007031"(peroxisome organization)|go:"GO:0015217"(ADP transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|go:"GO:0015867"(ATP transport)|interpro:IPR018108|interpro:IPR023395 refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:DH4ti6Peo5vXKjBQdHUMnb87XCs559292 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 intact-crc:8FF435E9B3EF5CB2|rigid:8jS84Yz4PogCJjxDMOeoAranDCM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12462 uniprotkb:Q07418 intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C intact:EBI-292|uniprotkb:D6VRT2|ensemblfungi:YDL065C psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:pex19_yeast(display_long)|uniprotkb:PEX19(gene name)|psi-mi:PEX19(display_short)|uniprotkb:PAS12(gene name synonym)|uniprotkb:YDL065C(locus name)|uniprotkb:Peroxin-19(gene name synonym)|uniprotkb:D2528(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348627|imex:IM-14275-3154 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) refseq:NP_010218.2|sgd:S000002223|dip:DIP-1563N|mint:Q07418|ensemblfungi:YDL065C(gene)|ensemblfungi:YDL065C_mRNA(transcript)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0033328"(peroxisome membrane targeting sequence binding)|go:"GO:0045033"(peroxisome inheritance)|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0050821"(protein stabilization)|go:"GO:1990415"|interpro:IPR006708(Pex19 protein)|interpro:IPR038322|reactome:R-SCE-1369062|reactome:R-SCE-9603798 psi-mi:"MI:0469"(intact) - crc64:B2FDE24970443D2A figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 rogid:u/Q3DGHpQR712xEWNu1B/m5V72I559292 intact-crc:D602DAB24FA49F13|rigid:rNbOrccATSbQqdZWMpNINJOIyag false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08215 uniprotkb:Q12462 intact:EBI-31849|uniprotkb:D6W222|ensemblfungi:YOL044W intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C psi-mi:pex15_yeast(display_long)|uniprotkb:Peroxisome biosynthesis protein PAS21(gene name synonym)|uniprotkb:PEX15(gene name)|psi-mi:PEX15(display_short)|uniprotkb:Peroxin-15(gene name synonym)|uniprotkb:PAS21(gene name synonym)|uniprotkb:YOL044W(locus name) psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348638|imex:IM-14275-3155 author score:99.25 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005404|refseq:NP_014598.1|dip:DIP-4159N|mint:Q08215|ensemblfungi:YOL044W(gene)|ensemblfungi:YOL044W_mRNA(transcript)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0043495"(protein-membrane adaptor activity)|rcsb pdb:5VXV refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) psi-mi:"MI:0469"(intact) crc64:B575A8D4B0DAC0B8 - figure legend:tables S3 and S4|author-confidence:99.25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:nNm7nOvPnFTR9KqeIR3fiw7oqeg559292 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 intact-crc:436918CEECEC1185|rigid:eO6zxHJMQe5oCT92842X6cJjwsE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12462 uniprotkb:Q12329 intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348649|imex:IM-14275-3156 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107 psi-mi:"MI:0469"(intact) - crc64:DF353A76493E3CE6 figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292 intact-crc:EB9635AC9FB5A9D9|rigid:V82O6nuKtImv2nS4ptuRwuLVTt4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12462 uniprotkb:Q12462 intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348660|imex:IM-14275-3157 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 intact-crc:D45C8CACBEC4238C|rigid:z99h4I+x9ZFmNHY/fDcajKp5Ye8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03640 uniprotkb:Q12466 intact:EBI-27872|uniprotkb:D6VZA1|ensemblfungi:YML072C intact:EBI-34614|uniprotkb:D6W2E8|ensemblfungi:YOR086C psi-mi:tcb3_yeast(display_long)|uniprotkb:YML072C(locus name)|uniprotkb:TCB3(gene name)|psi-mi:TCB3(display_short) psi-mi:tcb1_yeast(display_long)|uniprotkb:TCB1(gene name)|psi-mi:TCB1(display_short)|uniprotkb:YOR3141c(orf name)|uniprotkb:YOR086C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348671|imex:IM-14275-3158 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013639.1|sgd:S000004537|dip:DIP-6589N|mint:Q03640|ensemblfungi:YML072C(gene)|ensemblfungi:YML072C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 refseq:NP_014729.1|sgd:S000005612|mint:Q12466|dip:DIP-6292N|ensemblfungi:YOR086C(gene)|ensemblfungi:YOR086C_mRNA(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0071944"(cell periphery)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR017147(Tricalbin)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037756|interpro:IPR037761|interpro:IPR037762|interpro:IPR037765 psi-mi:"MI:0469"(intact) crc64:77A0AE57F9259784 crc64:1CD852549A6D82B1 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miu2Eqlp/xqS/9aOMycLTcERCEU559292 rogid:TCKJAc1j3Iok3OnfGsVzF8e6+x8559292 intact-crc:B826898B25F8D3AF|rigid:+v5h7t3R3xdFGv8mvjk9sMjDikI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12514 uniprotkb:P06102 intact:EBI-12184|uniprotkb:D6W476|ensemblfungi:YPR072W intact:EBI-12165|uniprotkb:D6VVP4|uniprotkb:Q6B233|ensemblfungi:YIL038C psi-mi:not5_yeast(display_long)|uniprotkb:NOT5(gene name)|psi-mi:NOT5(display_short)|uniprotkb:YP9499.27(orf name)|uniprotkb:YPR072W(locus name) psi-mi:not3_yeast(display_long)|uniprotkb:NOT3(gene name)|psi-mi:NOT3(display_short)|uniprotkb:YIL038C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348682|imex:IM-14275-3159 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPR072W(gene)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|rcsb pdb:6TB3|ensemblfungi:YPR072W_mRNA(transcript)|refseq:NP_015397.1|sgd:S000006276|dip:DIP-2257N|mint:Q12514 interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR038635|interpro:IPR040168|ensemblfungi:YIL038C(gene)|ensemblfungi:YIL038C_mRNA(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|refseq:NP_012226.3|sgd:S000001300|dip:DIP-2256N|mint:P06102 psi-mi:"MI:0469"(intact) crc64:073137119B3E92BC crc64:69B76694FCC6846F figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+XON8Ps4xCFhw058U9d2voUy2dc559292 rogid:EfakZPDNU3FZeI5+rnu7YV1UsCg559292 intact-crc:D5A9275D10B775A8|rigid:1IPsZU79IfZmMlyE9WSYYEYrB/w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25655 uniprotkb:Q12514 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-12184|uniprotkb:D6W476|ensemblfungi:YPR072W psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:not5_yeast(display_long)|uniprotkb:NOT5(gene name)|psi-mi:NOT5(display_short)|uniprotkb:YP9499.27(orf name)|uniprotkb:YPR072W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348693|imex:IM-14275-3160 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 ensemblfungi:YPR072W(gene)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|rcsb pdb:6TB3|ensemblfungi:YPR072W_mRNA(transcript)|refseq:NP_015397.1|sgd:S000006276|dip:DIP-2257N|mint:Q12514 psi-mi:"MI:0469"(intact) crc64:5B2AE15BCF95E009 crc64:073137119B3E92BC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:+XON8Ps4xCFhw058U9d2voUy2dc559292 intact-crc:91B8CC3FF68C1C3D|rigid:TBHDPUbFFXtQAOmtDJULM2bck1I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12514 uniprotkb:P34909 intact:EBI-12184|uniprotkb:D6W476|ensemblfungi:YPR072W intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W psi-mi:not5_yeast(display_long)|uniprotkb:NOT5(gene name)|psi-mi:NOT5(display_short)|uniprotkb:YP9499.27(orf name)|uniprotkb:YPR072W(locus name) psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348704|imex:IM-14275-3161 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPR072W(gene)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|rcsb pdb:6TB3|ensemblfungi:YPR072W_mRNA(transcript)|refseq:NP_015397.1|sgd:S000006276|dip:DIP-2257N|mint:Q12514 ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 psi-mi:"MI:0469"(intact) crc64:073137119B3E92BC crc64:8847084BD9BF48B7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+XON8Ps4xCFhw058U9d2voUy2dc559292 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 intact-crc:42E9F2869FD4FDC5|rigid:h70FSQhtn+Ex4dJzG8HMVjd1i3k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53829 uniprotkb:Q12514 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-12184|uniprotkb:D6W476|ensemblfungi:YPR072W psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:not5_yeast(display_long)|uniprotkb:NOT5(gene name)|psi-mi:NOT5(display_short)|uniprotkb:YP9499.27(orf name)|uniprotkb:YPR072W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348715|imex:IM-14275-3162 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 ensemblfungi:YPR072W(gene)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|rcsb pdb:6TB3|ensemblfungi:YPR072W_mRNA(transcript)|refseq:NP_015397.1|sgd:S000006276|dip:DIP-2257N|mint:Q12514 psi-mi:"MI:0469"(intact) crc64:F3DBABE6AD3C7F3C crc64:073137119B3E92BC figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:+XON8Ps4xCFhw058U9d2voUy2dc559292 intact-crc:D2B019C2D0AAACA5|rigid:O6qlgISdc32rXVT3kKeBYHIJwlE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12514 uniprotkb:P57743 intact:EBI-12184|uniprotkb:D6W476|ensemblfungi:YPR072W intact:EBI-10227|uniprotkb:Q05176|uniprotkb:Q06759|uniprotkb:D6VZ73|ensemblfungi:YLR438C-A psi-mi:not5_yeast(display_long)|uniprotkb:NOT5(gene name)|psi-mi:NOT5(display_short)|uniprotkb:YP9499.27(orf name)|uniprotkb:YPR072W(locus name) psi-mi:lsm3_yeast(display_long)|uniprotkb:LSM3(gene name)|psi-mi:LSM3(display_short)|uniprotkb:SMX4(gene name synonym)|uniprotkb:USS2(gene name synonym)|uniprotkb:YLR438C-A(locus name)|uniprotkb:SmX4 protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348726|imex:IM-14275-3163 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPR072W(gene)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|rcsb pdb:6TB3|ensemblfungi:YPR072W_mRNA(transcript)|refseq:NP_015397.1|sgd:S000006276|dip:DIP-2257N|mint:Q12514 sgd:S000006434|ensemblfungi:YLR438C-A(gene)|ensemblfungi:YLR438C-A_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034105|interpro:IPR040002|rcsb pdb:3BW1|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:4N0A|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039|rcsb pdb:4M75|refseq:NP_013543.3|dip:DIP-2587N|mint:P57743 psi-mi:"MI:0469"(intact) crc64:073137119B3E92BC crc64:787084EF6A5945B7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:+XON8Ps4xCFhw058U9d2voUy2dc559292 rogid:nYl7At1SnlSwN+nWr1F1xm0tdDE559292 intact-crc:83FA8B6A5A208035|rigid:5JoFI/4yfc144+DfIowGQz5kAxc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12522 uniprotkb:P35184 intact:EBI-9046|ensemblfungi:YPR016C|uniprotkb:D6W426 intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W psi-mi:if6_yeast(display_long)|uniprotkb:TIF6(gene name)|psi-mi:TIF6(display_short)|uniprotkb:CDC95(gene name synonym)|uniprotkb:YPR016C(locus name)|uniprotkb:LPZ15C(orf name) psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348737|imex:IM-14275-3164 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:6N8K|rcsb pdb:6N8L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R86|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:6EM1|rcsb pdb:6RZZ|rcsb pdb:6S05|rcsb pdb:6YLG|ensemblfungi:YPR016C(gene)|ensemblfungi:YPR016C_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR002769(Translation initiation factor IF6)|rcsb pdb:1G62|rcsb pdb:2X7N|rcsb pdb:3J2I|rcsb pdb:3JCT|rcsb pdb:4V7F|rcsb pdb:5FL8|rcsb pdb:5H4P|rcsb pdb:5JCS|rcsb pdb:5T62|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:7BTB|rcsb pdb:6YLH|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BT6|rcsb pdb:6ELZ|refseq:NP_015341.1|sgd:S000006220|mint:Q12522|dip:DIP-5395N refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184 psi-mi:"MI:0469"(intact) crc64:1BCE041C61DFD2A8 crc64:981D566076B0C881 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FI24/9LOZsCJEfbb7pjCQ+C8i/U559292 rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292 intact-crc:1C12E41DAF1E3C34|rigid:WaMM6xzT45anaEiYkN+DwwaMsP0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38861 uniprotkb:Q12522 intact:EBI-12077|uniprotkb:D3DLB9|ensemblfungi:YHR170W intact:EBI-9046|ensemblfungi:YPR016C|uniprotkb:D6W426 psi-mi:nmd3_yeast(display_long)|uniprotkb:YHR170W(locus name)|uniprotkb:NMD3(gene name)|psi-mi:NMD3(display_short)|uniprotkb:Nonsense-mediated mRNA decay protein 3(gene name synonym) psi-mi:if6_yeast(display_long)|uniprotkb:TIF6(gene name)|psi-mi:TIF6(display_short)|uniprotkb:CDC95(gene name synonym)|uniprotkb:YPR016C(locus name)|uniprotkb:LPZ15C(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348748|imex:IM-14275-3165 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR170W(gene)|ensemblfungi:YHR170W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|interpro:IPR007064(NMD3)|interpro:IPR039768|rcsb pdb:5H4P|rcsb pdb:5T6R|rcsb pdb:6N8K|rcsb pdb:6N8L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6QIK|rcsb pdb:6QTZ|rcsb pdb:6RI5|rcsb pdb:6RZZ|rcsb pdb:6S05|rcsb pdb:5T62|refseq:NP_012040.1|sgd:S000001213|mint:P38861|dip:DIP-1827N rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:6N8K|rcsb pdb:6N8L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R86|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:6EM1|rcsb pdb:6RZZ|rcsb pdb:6S05|rcsb pdb:6YLG|ensemblfungi:YPR016C(gene)|ensemblfungi:YPR016C_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR002769(Translation initiation factor IF6)|rcsb pdb:1G62|rcsb pdb:2X7N|rcsb pdb:3J2I|rcsb pdb:3JCT|rcsb pdb:4V7F|rcsb pdb:5FL8|rcsb pdb:5H4P|rcsb pdb:5JCS|rcsb pdb:5T62|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:7BTB|rcsb pdb:6YLH|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BT6|rcsb pdb:6ELZ|refseq:NP_015341.1|sgd:S000006220|mint:Q12522|dip:DIP-5395N psi-mi:"MI:0469"(intact) crc64:86405DDE49B3DCB4 crc64:1BCE041C61DFD2A8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:D86kkNFIwVjauOpXgA9HupEyfMc559292 rogid:FI24/9LOZsCJEfbb7pjCQ+C8i/U559292 intact-crc:DD3AA4E6D9C479FB|rigid:RqFo68t/7oMcO7Y+cl/0k9J3pPg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12522 uniprotkb:P53145 intact:EBI-9046|ensemblfungi:YPR016C|uniprotkb:D6W426 intact:EBI-23885|uniprotkb:D6VU46|ensemblfungi:YGL099W psi-mi:if6_yeast(display_long)|uniprotkb:TIF6(gene name)|psi-mi:TIF6(display_short)|uniprotkb:CDC95(gene name synonym)|uniprotkb:YPR016C(locus name)|uniprotkb:LPZ15C(orf name) psi-mi:lsg1_yeast(display_long)|uniprotkb:LSG1(gene name)|psi-mi:LSG1(display_short)|uniprotkb:YGL099W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348759|imex:IM-14275-3166 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:6N8K|rcsb pdb:6N8L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R86|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:6EM1|rcsb pdb:6RZZ|rcsb pdb:6S05|rcsb pdb:6YLG|ensemblfungi:YPR016C(gene)|ensemblfungi:YPR016C_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR002769(Translation initiation factor IF6)|rcsb pdb:1G62|rcsb pdb:2X7N|rcsb pdb:3J2I|rcsb pdb:3JCT|rcsb pdb:4V7F|rcsb pdb:5FL8|rcsb pdb:5H4P|rcsb pdb:5JCS|rcsb pdb:5T62|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:7BTB|rcsb pdb:6YLH|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BT6|rcsb pdb:6ELZ|refseq:NP_015341.1|sgd:S000006220|mint:Q12522|dip:DIP-5395N sgd:S000003067|refseq:NP_011416.3|dip:DIP-6659N|mint:P53145|ensemblfungi:YGL099W(gene)|ensemblfungi:YGL099W_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0043332"(mating projection tip)|interpro:IPR006073(GTP1/OBG)|interpro:IPR027417|interpro:IPR030378|interpro:IPR043358|rcsb pdb:5T62|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6QIK|rcsb pdb:6QTZ|rcsb pdb:6RI5|rcsb pdb:6RZZ|rcsb pdb:6S05 psi-mi:"MI:0469"(intact) crc64:1BCE041C61DFD2A8 crc64:15FD76541A2E8410 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FI24/9LOZsCJEfbb7pjCQ+C8i/U559292 rogid:9mANWO3rTsE/zCUr9GL6WxIexMU559292 intact-crc:C614813C63799541|rigid:QAanUzUJKCrihDF8FCWi+0N3Vwg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53742 uniprotkb:Q12522 intact:EBI-28532|uniprotkb:D6W1M8|ensemblfungi:YNR053C intact:EBI-9046|ensemblfungi:YPR016C|uniprotkb:D6W426 psi-mi:nog2_yeast(display_long)|uniprotkb:NOG2(gene name)|psi-mi:NOG2(display_short)|uniprotkb:N3484(orf name)|uniprotkb:YNR053C(locus name) psi-mi:if6_yeast(display_long)|uniprotkb:TIF6(gene name)|psi-mi:TIF6(display_short)|uniprotkb:CDC95(gene name synonym)|uniprotkb:YPR016C(locus name)|uniprotkb:LPZ15C(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348770|imex:IM-14275-3167 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014451.1|sgd:S000005336|dip:DIP-976N|mint:P53742|ensemblfungi:YNR053C(gene)|ensemblfungi:YNR053C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:2000200"(regulation of ribosomal subunit export from nucleus)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012971(NGP1, N-terminal)|interpro:IPR023179|interpro:IPR024929|interpro:IPR027417|interpro:IPR030378|rcsb pdb:3JCT|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:6YLG|rcsb pdb:6YLH|rcsb pdb:7BT6|rcsb pdb:7BTB rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:6N8K|rcsb pdb:6N8L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R86|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:6EM1|rcsb pdb:6RZZ|rcsb pdb:6S05|rcsb pdb:6YLG|ensemblfungi:YPR016C(gene)|ensemblfungi:YPR016C_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR002769(Translation initiation factor IF6)|rcsb pdb:1G62|rcsb pdb:2X7N|rcsb pdb:3J2I|rcsb pdb:3JCT|rcsb pdb:4V7F|rcsb pdb:5FL8|rcsb pdb:5H4P|rcsb pdb:5JCS|rcsb pdb:5T62|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:7BTB|rcsb pdb:6YLH|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BT6|rcsb pdb:6ELZ|refseq:NP_015341.1|sgd:S000006220|mint:Q12522|dip:DIP-5395N psi-mi:"MI:0469"(intact) crc64:D7F670973B85CCEB crc64:1BCE041C61DFD2A8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:oWCL90Qd+LFA4SHdZgdz0gtSD0I559292 rogid:FI24/9LOZsCJEfbb7pjCQ+C8i/U559292 intact-crc:B777C723510ED39A|rigid:beDHrlz12lxvVrPchtyv7sha9YE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12522 uniprotkb:Q02256 intact:EBI-9046|ensemblfungi:YPR016C|uniprotkb:D6W426 intact:EBI-14322|uniprotkb:D6VVV7|ensemblfungi:YIR026C psi-mi:if6_yeast(display_long)|uniprotkb:TIF6(gene name)|psi-mi:TIF6(display_short)|uniprotkb:CDC95(gene name synonym)|uniprotkb:YPR016C(locus name)|uniprotkb:LPZ15C(orf name) psi-mi:pvh1_yeast(display_long)|uniprotkb:YIR026C(locus name)|uniprotkb:YVH1(gene name)|psi-mi:YVH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348781|imex:IM-14275-3168 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:6N8K|rcsb pdb:6N8L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R86|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:6EM1|rcsb pdb:6RZZ|rcsb pdb:6S05|rcsb pdb:6YLG|ensemblfungi:YPR016C(gene)|ensemblfungi:YPR016C_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR002769(Translation initiation factor IF6)|rcsb pdb:1G62|rcsb pdb:2X7N|rcsb pdb:3J2I|rcsb pdb:3JCT|rcsb pdb:4V7F|rcsb pdb:5FL8|rcsb pdb:5H4P|rcsb pdb:5JCS|rcsb pdb:5T62|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:7BTB|rcsb pdb:6YLH|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BT6|rcsb pdb:6ELZ|refseq:NP_015341.1|sgd:S000006220|mint:Q12522|dip:DIP-5395N ensemblfungi:YIR026C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|ensemblfungi:YIR026C(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1990275"(preribosome binding)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|sgd:S000001465|interpro:IPR020422|interpro:IPR029021|rcsb pdb:6N8M|interpro:IPR016278(Tyrosine protein phosphatase, dual specificity, 12)|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6RZZ|rcsb pdb:6S05|refseq:NP_012292.3|mint:Q02256|dip:DIP-5192N psi-mi:"MI:0469"(intact) crc64:1BCE041C61DFD2A8 crc64:9E75C7CC14353B43 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:FI24/9LOZsCJEfbb7pjCQ+C8i/U559292 rogid:9C9+S3aubsVjSLE5Kklpws+PA0A559292 intact-crc:63CF75FCAA22873E|rigid:1JrUUzw4bEjqckEsQJy8NnCUUYw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08235 uniprotkb:Q12522 intact:EBI-3775|uniprotkb:D6W1Z1|ensemblfungi:YOL077C intact:EBI-9046|ensemblfungi:YPR016C|uniprotkb:D6W426 psi-mi:brx1_yeast(display_long)|uniprotkb:YOL077C(locus name)|uniprotkb:BRX1(gene name)|psi-mi:BRX1(display_short) psi-mi:if6_yeast(display_long)|uniprotkb:TIF6(gene name)|psi-mi:TIF6(display_short)|uniprotkb:CDC95(gene name synonym)|uniprotkb:YPR016C(locus name)|uniprotkb:LPZ15C(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348792|imex:IM-14275-3169 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014565.2|sgd:S000005437|dip:DIP-6317N|mint:Q08235|ensemblfungi:YOL077C(gene)|ensemblfungi:YOL077C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000464"("endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000465"("exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR007109(Brix)|interpro:IPR026532|rcsb pdb:5Z1G|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5 rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:6N8K|rcsb pdb:6N8L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R86|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:6EM1|rcsb pdb:6RZZ|rcsb pdb:6S05|rcsb pdb:6YLG|ensemblfungi:YPR016C(gene)|ensemblfungi:YPR016C_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR002769(Translation initiation factor IF6)|rcsb pdb:1G62|rcsb pdb:2X7N|rcsb pdb:3J2I|rcsb pdb:3JCT|rcsb pdb:4V7F|rcsb pdb:5FL8|rcsb pdb:5H4P|rcsb pdb:5JCS|rcsb pdb:5T62|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:7BTB|rcsb pdb:6YLH|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BT6|rcsb pdb:6ELZ|refseq:NP_015341.1|sgd:S000006220|mint:Q12522|dip:DIP-5395N psi-mi:"MI:0469"(intact) crc64:31466853EF0E7301 crc64:1BCE041C61DFD2A8 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:mPR6HWKwM6RNCRE/vezsYlCmEGY559292 rogid:FI24/9LOZsCJEfbb7pjCQ+C8i/U559292 intact-crc:9783D03B76271638|rigid:yKXnclt355OaubmGXL2lEgTNLc4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12525 uniprotkb:Q12043 intact:EBI-37133|uniprotkb:D6VXU7|ensemblfungi:YLL062C intact:EBI-34845|uniprotkb:Q7LH13|uniprotkb:D6W2E4|ensemblfungi:YOR081C psi-mi:mht1_yeast(display_long)|uniprotkb:MHT1(gene name)|psi-mi:MHT1(display_short)|uniprotkb:L0552(orf name)|uniprotkb:YLL062C(locus name)|uniprotkb:"S-methylmethionine:homocysteine methyltransferase 1"(gene name synonym) psi-mi:tgl5_yeast(display_long)|uniprotkb:TGL5(gene name)|psi-mi:TGL5(display_short)|uniprotkb:STC2(gene name synonym)|uniprotkb:YOR29-32(orf name)|uniprotkb:YOR2964C(orf name)|uniprotkb:YOR081C(locus name)|uniprotkb:Lipase 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348803|imex:IM-14275-3170 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013038.1|sgd:S000003985|mint:Q12525|dip:DIP-1934N|ensemblfungi:YLL062C(gene)|ensemblfungi:YLL062C_mRNA(transcript)|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008898"(S-adenosylmethionine-homocysteine S-methyltransferase activity)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0032259"(methylation)|go:"GO:0047150"(betaine-homocysteine S-methyltransferase activity)|go:"GO:0061627"(S-methylmethionine-homocysteine S-methyltransferase activity)|interpro:IPR003726(Homocysteine S-methyltransferase)|interpro:IPR017226(Betaine--homocysteine S-methyltransferase, BHMT)|interpro:IPR036589 refseq:NP_014724.1|sgd:S000005607|mint:Q12043|dip:DIP-6280N|ensemblfungi:YOR081C(gene)|ensemblfungi:YOR081C_mRNA(transcript)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042171"(lysophosphatidic acid acyltransferase activity)|interpro:IPR002641(Patatin)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR021771 psi-mi:"MI:0469"(intact) crc64:A77194694B6E5C14 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:6TJvgaM7ZswSv8/DI3EMcQUrsNM559292 rogid:ccHxygbWfyyQXKaSbOL4iYhikms559292 intact-crc:65E278F77EC4E6B5|rigid:/oBGkea5F0/fOMpM75AoR5PtAqc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32660 uniprotkb:Q12675 intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W intact:EBI-3114|uniprotkb:D6VS80|ensemblfungi:YDR093W psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:atc4_yeast(display_long)|uniprotkb:DNF2(gene name)|psi-mi:DNF2(display_short)|uniprotkb:YDR093W(locus name)|uniprotkb:YD8557.01(orf name)|uniprotkb:Flippase DNF2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348814|imex:IM-14275-3171 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) refseq:NP_010378.1|sgd:S000002500|dip:DIP-8055N|mint:Q12675|ensemblfungi:YDR093W(gene)|ensemblfungi:YDR093W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015031"(protein transport)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY5|rcsb pdb:7KY7|rcsb pdb:7KY8|rcsb pdb:7KY9|rcsb pdb:7KYA psi-mi:"MI:0469"(intact) crc64:3CC3FBA8ADDE8960 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 rogid:yfYH/L8WpAsxluGHGiYw3loRtRM559292 intact-crc:02D5C3363E967964|rigid:JHOki/TpxXmMpRQ/Eq8bAQpVpw4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36027 uniprotkb:Q12675 intact:EBI-10901|uniprotkb:P41944|ensemblfungi:YLR332W|uniprotkb:D6VYX3 intact:EBI-3114|uniprotkb:D6VS80|ensemblfungi:YDR093W psi-mi:mid2_yeast(display_long)|uniprotkb:SMS1(gene name synonym)|uniprotkb:L8543.19(orf name)|uniprotkb:YLR332W(locus name)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:Mating pheromone-induced death protein 2(gene name synonym)|uniprotkb:Serine-rich multicopy suppressor protein 1(gene name synonym)|uniprotkb:Protein kinase A interference protein 1(gene name synonym) psi-mi:atc4_yeast(display_long)|uniprotkb:DNF2(gene name)|psi-mi:DNF2(display_short)|uniprotkb:YDR093W(locus name)|uniprotkb:YD8557.01(orf name)|uniprotkb:Flippase DNF2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348825|imex:IM-14275-3172 author score:99.28 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR332W(gene)|ensemblfungi:YLR332W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000767"(cell morphogenesis involved in conjugation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043332"(mating projection tip)|interpro:IPR007567(Mid2 like cell wall stress sensor)|refseq:NP_013436.1|sgd:S000004324|mint:P36027|dip:DIP-4676N refseq:NP_010378.1|sgd:S000002500|dip:DIP-8055N|mint:Q12675|ensemblfungi:YDR093W(gene)|ensemblfungi:YDR093W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015031"(protein transport)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY5|rcsb pdb:7KY7|rcsb pdb:7KY8|rcsb pdb:7KY9|rcsb pdb:7KYA psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:o4cMDBqIZorgGZ6iEACUFcfgO7I559292 rogid:yfYH/L8WpAsxluGHGiYw3loRtRM559292 intact-crc:F9C4BBCD1E14CB2B|rigid:GWF8tUmDudoIGEgjHiM5mIIxoiE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42838 uniprotkb:Q12675 intact:EBI-28396|uniprotkb:D6W0M3|ensemblfungi:YNL323W intact:EBI-3114|uniprotkb:D6VS80|ensemblfungi:YDR093W psi-mi:lem3_yeast(display_long)|uniprotkb:LEM3(gene name)|psi-mi:LEM3(display_short)|uniprotkb:BRE3(gene name synonym)|uniprotkb:Ro-sensitive 3(gene name synonym)|uniprotkb:Brefeldin-A sensitivity protein 3(gene name synonym)|uniprotkb:ROS3(gene name synonym)|uniprotkb:N0333(orf name)|uniprotkb:YNL323W(locus name) psi-mi:atc4_yeast(display_long)|uniprotkb:DNF2(gene name)|psi-mi:DNF2(display_short)|uniprotkb:YDR093W(locus name)|uniprotkb:YD8557.01(orf name)|uniprotkb:Flippase DNF2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348836|imex:IM-14275-3173 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014076.1|sgd:S000005267|dip:DIP-4598N|mint:P42838|ensemblfungi:YNL323W(gene)|ensemblfungi:YNL323W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044088"(regulation of vacuole organization)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0140331"(aminophospholipid translocation)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|rcsb pdb:7KY5|rcsb pdb:7KY7|rcsb pdb:7KY8|rcsb pdb:7KY9|rcsb pdb:7KYA|rcsb pdb:7KYB|rcsb pdb:7KYC|reactome:R-SCE-6798695 refseq:NP_010378.1|sgd:S000002500|dip:DIP-8055N|mint:Q12675|ensemblfungi:YDR093W(gene)|ensemblfungi:YDR093W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015031"(protein transport)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY5|rcsb pdb:7KY7|rcsb pdb:7KY8|rcsb pdb:7KY9|rcsb pdb:7KYA psi-mi:"MI:0469"(intact) crc64:55BDA1F32251B4E6 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:YNU4U5F2bWdXZvJYQ9HK0iWX230559292 rogid:yfYH/L8WpAsxluGHGiYw3loRtRM559292 intact-crc:8719759FE42C404B|rigid:9kQ3U7Pz+xjpely9lMrFxAaqfxo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12692 uniprotkb:P53551 intact:EBI-8080|uniprotkb:D6W255|ensemblfungi:YOL012C intact:EBI-8064|uniprotkb:Q6Q5R6|uniprotkb:D6W3P0|ensemblfungi:YPL127C psi-mi:h2az_yeast(display_long)|uniprotkb:HTZ1(gene name)|psi-mi:HTZ1(display_short)|uniprotkb:H2AZ(gene name synonym)|uniprotkb:YOL012C(locus name)|uniprotkb:HTA3(gene name synonym)|uniprotkb:O2345(orf name) psi-mi:h1_yeast(display_long)|uniprotkb:HHO1(gene name)|psi-mi:HHO1(display_short)|uniprotkb:LPI17C(orf name)|uniprotkb:YPL127C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348847|imex:IM-14275-3174 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014631.1|sgd:S000005372|mint:Q12692|dip:DIP-1381N|ensemblfungi:YOL012C(gene)|ensemblfungi:YOL012C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006342"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:2FSB|rcsb pdb:2JSS|rcsb pdb:4M6B|rcsb pdb:5J9Q|rcsb pdb:6AE8|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-9018519 refseq:NP_015198.1|sgd:S000006048|mint:P53551|dip:DIP-6587N|ensemblfungi:YPL127C(gene)|ensemblfungi:YPL127C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0097100"(supercoiled DNA binding)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1UHM|rcsb pdb:1USS|rcsb pdb:1UST|rcsb pdb:1YQA psi-mi:"MI:0469"(intact) crc64:1D8FCEE3C8A504E7 crc64:B0C53AC186E49F96 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WNtmWZ+w+lXKNqAqIp0T4u28siw559292 rogid:dPMYSAq1Cr7pfGGNgb3GDp3LnsQ559292 intact-crc:0E26E6A1D41BA83B|rigid:fctY4L5Xo2fQcpG3OnXIDEXMBIQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38634 uniprotkb:Q3E840 intact:EBI-17127|ensemblfungi:YLR079W|uniprotkb:D6VY79 intact:EBI-2055307|uniprotkb:D6VPT1|ensemblfungi:YBL071W-A psi-mi:sic1_yeast(display_long)|uniprotkb:SIC1(gene name)|psi-mi:SIC1(display_short)|uniprotkb:SDB25(gene name synonym)|uniprotkb:YLR079W(locus name)|uniprotkb:L9449.8(orf name)|uniprotkb:CDK inhibitor p40(gene name synonym) psi-mi:dph3_yeast(display_long)|uniprotkb:DPH3(gene name synonym)|uniprotkb:Kluyveromyces lactis toxin-insensitive protein 11(gene name synonym)|uniprotkb:YBL071W-A(locus name)|uniprotkb:KTI11(gene name)|psi-mi:KTI11(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348858|imex:IM-14275-3175 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR079W(gene)|ensemblfungi:YLR079W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016242"(negative regulation of macroautophagy)|rcsb pdb:3V7D|rcsb pdb:6G86|refseq:NP_013180.1|sgd:S000004069|dip:DIP-6817N|mint:P38634 refseq:NP_660100.1|sgd:S000007587|dip:DIP-52225N|mint:Q3E840|ensemblfungi:YBL071W-A(gene)|ensemblfungi:YBL071W-A_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016730"(oxidoreductase activity, acting on iron-sulfur proteins as donors)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|interpro:IPR007872(Zinc finger, DPH-type)|interpro:IPR036671|interpro:IPR044248|rcsb pdb:1YOP|rcsb pdb:1YWS|rcsb pdb:4D4O|rcsb pdb:4D4P|rcsb pdb:4X33|rcsb pdb:5AX2|reactome:R-SCE-5358493 psi-mi:"MI:0469"(intact) crc64:7913636340678F78 crc64:8B27A307831B0ECE figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:qU8ivBCZHvG4VmXDxv52yc08Hwc559292 rogid:GwQlZVh0IRJ/OMoCjHic//fuHZE559292 intact-crc:62283C3A24AE6CED|rigid:pRfA8K+16qcnl0/Iv1QL6MzLoTg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3E840 uniprotkb:P42935 intact:EBI-2055307|uniprotkb:D6VPT1|ensemblfungi:YBL071W-A intact:EBI-23459|uniprotkb:D6VUY2|uniprotkb:E9P8V1|ensemblfungi:YGR200C psi-mi:dph3_yeast(display_long)|uniprotkb:DPH3(gene name synonym)|uniprotkb:Kluyveromyces lactis toxin-insensitive protein 11(gene name synonym)|uniprotkb:YBL071W-A(locus name)|uniprotkb:KTI11(gene name)|psi-mi:KTI11(display_short) psi-mi:elp2_yeast(display_long)|uniprotkb:YGR200C(locus name)|uniprotkb:G7725(orf name)|uniprotkb:ELP2(gene name)|psi-mi:ELP2(display_short)|uniprotkb:TOT2(gene name synonym)|uniprotkb:Gamma-toxin target 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348869|imex:IM-14275-3176 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_660100.1|sgd:S000007587|dip:DIP-52225N|mint:Q3E840|ensemblfungi:YBL071W-A(gene)|ensemblfungi:YBL071W-A_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016730"(oxidoreductase activity, acting on iron-sulfur proteins as donors)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|interpro:IPR007872(Zinc finger, DPH-type)|interpro:IPR036671|interpro:IPR044248|rcsb pdb:1YOP|rcsb pdb:1YWS|rcsb pdb:4D4O|rcsb pdb:4D4P|rcsb pdb:4X33|rcsb pdb:5AX2|reactome:R-SCE-5358493 sgd:S000003432|refseq:NP_011716.3|dip:DIP-2386N|mint:P42935|ensemblfungi:YGR200C(gene)|ensemblfungi:YGR200C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008017"(microtubule binding)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0015031"(protein transport)|go:"GO:0032447"(protein urmylation)|go:"GO:0033588"(elongator holoenzyme complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037289|rcsb pdb:4XFV|rcsb pdb:5M2N|rcsb pdb:6QK7 psi-mi:"MI:0469"(intact) crc64:8B27A307831B0ECE crc64:5371908FE2E6EC0D figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:GwQlZVh0IRJ/OMoCjHic//fuHZE559292 rogid:uBbnUH2xCo3Fu5LlxbrLxO43irk559292 intact-crc:66E44E78BEED0181|rigid:DdtaEliPVPiYh4j4zOlcJSrMsNk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11986 uniprotkb:Q6Q5K6 intact:EBI-9257|ensemblfungi:YJL153C|uniprotkb:D6VW34 intact:EBI-392766|ensemblfungi:YML058W-A|uniprotkb:D6VZB5 psi-mi:ino1_yeast(display_long)|uniprotkb:INO1(gene name)|psi-mi:INO1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym)|uniprotkb:J0610(orf name)|uniprotkb:YJL153C(locus name) psi-mi:hug1_yeast(display_long)|uniprotkb:HUG1(gene name)|psi-mi:HUG1(display_short)|uniprotkb:YML058W-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348880|imex:IM-14275-3177 author score:98.72 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1P1K|ensemblfungi:YJL153C(gene)|ensemblfungi:YJL153C_mRNA(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|rcsb pdb:1JKF|rcsb pdb:1JKI|rcsb pdb:1LA2|rcsb pdb:1P1F|rcsb pdb:1P1H|rcsb pdb:1P1I|rcsb pdb:1P1J|rcsb pdb:1RM0|reactome:R-SCE-1855183|refseq:NP_012382.2|sgd:S000003689|dip:DIP-5687N|mint:P11986 ensemblfungi:YML058W-A(gene)|ensemblfungi:YML058W-A_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:1905117"(regulation of ribonucleoside-diphosphate reductase activity)|go:"GO:1990846"(ribonucleoside-diphosphate reductase inhibitor activity)|sgd:S000007472|refseq:NP_219498.1|mint:Q6Q5K6 psi-mi:"MI:0469"(intact) crc64:282E2AE5D156289D - figure legend:tables S3 and S4|author-confidence:98.72|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:3OB3q28fOVxXSBMwMpLe2c1g8p8559292 rogid:x+quBrnP+8yql7JGQ1NK4j5ubbw559292 intact-crc:8C22DF576A7A5AEE|rigid:CaafvVGWw3ZAi/wnYOlBfw2VJ2Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37012 uniprotkb:Q6Q5K6 intact:EBI-13296|uniprotkb:D6VZS7|ensemblfungi:YMR105C intact:EBI-392766|ensemblfungi:YML058W-A|uniprotkb:D6VZB5 psi-mi:pgm2_yeast(display_long)|uniprotkb:PGM2(gene name)|psi-mi:PGM2(display_short)|uniprotkb:GAL5(gene name synonym)|uniprotkb:YMR105C(locus name)|uniprotkb:YM9718.04C(orf name)|uniprotkb:Glucose phosphomutase 2(gene name synonym)|uniprotkb:"D-glucose-1,6-diphosphate:D-glucose-1-phosphate phosphotransferase"(gene name synonym)|uniprotkb:GA-5(gene name synonym) psi-mi:hug1_yeast(display_long)|uniprotkb:HUG1(gene name)|psi-mi:HUG1(display_short)|uniprotkb:YML058W-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348891|imex:IM-14275-3178 author score:97.54 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013823.1|sgd:S000004711|mint:P37012|dip:DIP-6499N|ensemblfungi:YMR105C(gene)|ensemblfungi:YMR105C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004614"(phosphoglucomutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019255"(glucose 1-phosphate metabolic process)|go:"GO:0019388"(galactose catabolic process)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR036900 ensemblfungi:YML058W-A(gene)|ensemblfungi:YML058W-A_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:1905117"(regulation of ribonucleoside-diphosphate reductase activity)|go:"GO:1990846"(ribonucleoside-diphosphate reductase inhibitor activity)|sgd:S000007472|refseq:NP_219498.1|mint:Q6Q5K6 psi-mi:"MI:0469"(intact) crc64:45B78AFF8197645E - figure legend:tables S3 and S4|author-confidence:97.54|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:miT4vpKTbsa/OfXIppW6h1+TbPs559292 rogid:x+quBrnP+8yql7JGQ1NK4j5ubbw559292 intact-crc:D6A78BBD757BC38F|rigid:1vFLeyXzxDHjQEL2qZiMOHux1N8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6Q5K6 uniprotkb:P38009 intact:EBI-392766|ensemblfungi:YML058W-A|uniprotkb:D6VZB5 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 psi-mi:hug1_yeast(display_long)|uniprotkb:HUG1(gene name)|psi-mi:HUG1(display_short)|uniprotkb:YML058W-A(locus name) psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348902|imex:IM-14275-3179 author score:99.31 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML058W-A(gene)|ensemblfungi:YML058W-A_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:1905117"(regulation of ribonucleoside-diphosphate reductase activity)|go:"GO:1990846"(ribonucleoside-diphosphate reductase inhibitor activity)|sgd:S000007472|refseq:NP_219498.1|mint:Q6Q5K6 refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N psi-mi:"MI:0469"(intact) - crc64:8ABA71761B512242 figure legend:tables S3 and S4|author-confidence:99.31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:x+quBrnP+8yql7JGQ1NK4j5ubbw559292 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 intact-crc:5CCE091A55A0EA18|rigid:6YUhZra/DUgathdEhGPWml0gopQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6WNK7 uniprotkb:Q08281 intact:EBI-1251050|uniprotkb:D6VQB1|ensemblfungi:YBR111W-A intact:EBI-2047093|uniprotkb:D6W1T1|uniprotkb:Q92271|ensemblfungi:YOL138C psi-mi:sus1_yeast(display_long)|uniprotkb:SUS1(gene name)|psi-mi:SUS1(display_short)|uniprotkb:YBR111W-A(locus name) psi-mi:rtc1_yeast(display_long)|uniprotkb:RTC1(gene name)|psi-mi:RTC1(display_short)|uniprotkb:SEA2(gene name synonym)|uniprotkb:SEH-associated protein 2(gene name synonym)|uniprotkb:YOL138C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348913|imex:IM-14275-3180 author score:99.29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_878049.2|sgd:S000028510|mint:Q6WNK7|dip:DIP-45499N|ensemblfungi:YBR111W-A_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000932"(P-body)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|go:"GO:0071819"(DUBm complex)|interpro:IPR018783|interpro:IPR038212|rcsb pdb:3FWB|rcsb pdb:3FWC|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:4C31|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4MBE|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L|rcsb pdb:3MHS|ensemblfungi:YBR111W-A(gene) interpro:IPR037590|refseq:NP_014503.2|sgd:S000005498|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q08281|interpro:IPR036322|ensemblfungi:YOL138C(gene)|ensemblfungi:YOL138C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0035859"(Seh1-associated complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0097042"(extrinsic component of fungal-type vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling) psi-mi:"MI:0469"(intact) crc64:DB0DA0C9DC13FB21 - figure legend:tables S3 and S4|author-confidence:99.29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:gR8l71iy7VBJ/AS7bXueosdEJqU559292 rogid:3k6vZ9TxDj/BcLSmeJdAg45Ri14559292 intact-crc:30ED10765B917750|rigid:aeVXXXRlYdrZa/vREaufZ9Zto70 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6WNK7 uniprotkb:Q08748 intact:EBI-1251050|uniprotkb:D6VQB1|ensemblfungi:YBR111W-A intact:EBI-2050125|uniprotkb:D6W2Z5|ensemblfungi:YOR296W psi-mi:sus1_yeast(display_long)|uniprotkb:SUS1(gene name)|psi-mi:SUS1(display_short)|uniprotkb:YBR111W-A(locus name) psi-mi:yo296_yeast(display_long)|uniprotkb:YOR296W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348924|imex:IM-14275-3181 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_878049.2|sgd:S000028510|mint:Q6WNK7|dip:DIP-45499N|ensemblfungi:YBR111W-A_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000932"(P-body)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|go:"GO:0071819"(DUBm complex)|interpro:IPR018783|interpro:IPR038212|rcsb pdb:3FWB|rcsb pdb:3FWC|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:4C31|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4MBE|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L|rcsb pdb:3MHS|ensemblfungi:YBR111W-A(gene) refseq:NP_014939.1|sgd:S000005822|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR014770(Munc13 homology 1)|interpro:IPR014772(Munc13 homology 2)|interpro:IPR019558|mint:Q08748|interpro:IPR035892|ensemblfungi:YOR296W(gene)|ensemblfungi:YOR296W_mRNA(transcript)|go:"GO:0005737"(cytoplasm) psi-mi:"MI:0469"(intact) crc64:DB0DA0C9DC13FB21 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:gR8l71iy7VBJ/AS7bXueosdEJqU559292 rogid:SMFMKeDnBPQzBm5c8hrj9GOokpg559292 intact-crc:BA3FC6373A2C4F3E|rigid:Lf62rlOoDuKlMbupzUjldQdDNYU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92317 uniprotkb:P40096 intact:EBI-37723|uniprotkb:O00064|uniprotkb:P87340|uniprotkb:Q04176|uniprotkb:D6VT30|ensemblfungi:YDR397C intact:EBI-11908|ensemblfungi:YER159C|uniprotkb:D3DM66 psi-mi:ncb2_yeast(display_long)|uniprotkb:NCB2(gene name)|psi-mi:NCB2(display_short)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Transcriptional repressor YDR1(gene name synonym)|uniprotkb:YDR397C(locus name) psi-mi:ncb1_yeast(display_long)|uniprotkb:BUR6(gene name)|psi-mi:BUR6(display_short)|uniprotkb:NCB1(gene name synonym)|uniprotkb:Transcription repressor BUR6(gene name synonym)|uniprotkb:YER159C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348935|imex:IM-14275-3182 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010685.1|sgd:S000002805|dip:DIP-2067N|mint:Q92317|ensemblfungi:YDR397C(gene)|ensemblfungi:YDR397C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0017054"(negative cofactor 2 complex)|go:"GO:0045898"(regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|interpro:IPR042225 ensemblfungi:YER159C(gene)|ensemblfungi:YER159C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017054"(negative cofactor 2 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|interpro:IPR027116|go:"GO:0005634"(nucleus)|refseq:NP_011086.3|sgd:S000000961|mint:P40096|dip:DIP-2066N psi-mi:"MI:0469"(intact) crc64:E04EB0D6F7E8D91D crc64:27341BD250973BA7 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:lqILVmsMA1YDORBEGe4Xp4dsBQA559292 rogid:80vZFpRN7MVRN9/zvGyJI4ak7gA559292 intact-crc:758FF8C2E90360EB|rigid:6ywc7Vi9829MXjnQBR0tCDLKGMM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92331 uniprotkb:P32319 intact:EBI-20483|uniprotkb:Q08483|uniprotkb:D6W2D1|uniprotkb:E9P8U6|ensemblfungi:YOR069W intact:EBI-13123|uniprotkb:D6VPY3|ensemblfungi:YBL017C psi-mi:vps5_yeast(display_long)|uniprotkb:VPS5(gene name)|psi-mi:VPS5(display_short)|uniprotkb:GRD2(gene name synonym)|uniprotkb:PEP10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 5(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 10(gene name synonym)|uniprotkb:VPT5(gene name synonym)|uniprotkb:YOR29-20(orf name)|uniprotkb:YOR069W(locus name) psi-mi:vps10_yeast(display_long)|uniprotkb:PEP1(gene name)|psi-mi:PEP1(display_short)|uniprotkb:Vacuolar carboxypeptidase sorting receptor VPS10(gene name synonym)|uniprotkb:Carboxypeptidase Y receptor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 1(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 1(gene name synonym)|uniprotkb:Sortilin VPS10(gene name synonym)|uniprotkb:VPS10(gene name synonym)|uniprotkb:VPT1(gene name synonym)|uniprotkb:YBL03.22(orf name)|uniprotkb:YBL0302(orf name)|uniprotkb:YBL017C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348946|imex:IM-14275-3183 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014712.2|sgd:S000005595|ensemblfungi:YOR069W(gene)|ensemblfungi:YOR069W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0005768"(endosome)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|interpro:IPR001683(Phox-like)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028648|interpro:IPR035803|interpro:IPR036871|interpro:IPR037868|dip:DIP-1740N|mint:Q92331 refseq:NP_009536.1|sgd:S000000113|mint:P32319|dip:DIP-5900N|ensemblfungi:YBL017C(gene)|ensemblfungi:YBL017C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000423"(mitophagy)|go:"GO:0000425"(pexophagy)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048203"(vesicle targeting, trans-Golgi to endosome)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR036278 psi-mi:"MI:0469"(intact) - crc64:C778A0400612ECF4 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5aPSkQUJV1sfIc9Ql+wMP74Y3QI559292 rogid:dYYsekAaDw4SzmEUSe5tYb5a43M559292 intact-crc:F4533574A237445E|rigid:RZlpQHih751xH9nO+Uzb9A+5QI8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92331 uniprotkb:P32913 intact:EBI-20483|uniprotkb:Q08483|uniprotkb:D6W2D1|uniprotkb:E9P8U6|ensemblfungi:YOR069W intact:EBI-20366|uniprotkb:Q12279|uniprotkb:D6W2J0|ensemblfungi:YOR132W psi-mi:vps5_yeast(display_long)|uniprotkb:VPS5(gene name)|psi-mi:VPS5(display_short)|uniprotkb:GRD2(gene name synonym)|uniprotkb:PEP10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 5(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 10(gene name synonym)|uniprotkb:VPT5(gene name synonym)|uniprotkb:YOR29-20(orf name)|uniprotkb:YOR069W(locus name) psi-mi:vps17_yeast(display_long)|uniprotkb:VPS17(gene name)|psi-mi:VPS17(display_short)|uniprotkb:PEP21(gene name synonym)|uniprotkb:YOR132W(locus name)|uniprotkb:O3314(orf name)|uniprotkb:YOR3314W(orf name)|uniprotkb:Carboxypeptidase Y-deficient protein 21(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348957|imex:IM-14275-3184 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014712.2|sgd:S000005595|ensemblfungi:YOR069W(gene)|ensemblfungi:YOR069W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0005768"(endosome)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|interpro:IPR001683(Phox-like)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028648|interpro:IPR035803|interpro:IPR036871|interpro:IPR037868|dip:DIP-1740N|mint:Q92331 sgd:S000005658|refseq:NP_014775.3|ensemblfungi:YOR132W(gene)|ensemblfungi:YOR132W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR001683(Phox-like)|interpro:IPR014461(Vacuolar protein sorting-associated protein Vps17)|interpro:IPR027267|interpro:IPR036871|interpro:IPR037907|dip:DIP-1739N|mint:P32913 psi-mi:"MI:0469"(intact) - crc64:C709968468144A50 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5aPSkQUJV1sfIc9Ql+wMP74Y3QI559292 rogid:X5nNIyX3T0PYprdyJaxVnc8RoR8559292 intact-crc:64F6FF58332427F5|rigid:7oteIkllY4V4dczAOKbHCabO1t0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92331 uniprotkb:P34110 intact:EBI-20483|uniprotkb:Q08483|uniprotkb:D6W2D1|uniprotkb:E9P8U6|ensemblfungi:YOR069W intact:EBI-20415|uniprotkb:D6VW33|ensemblfungi:YJL154C psi-mi:vps5_yeast(display_long)|uniprotkb:VPS5(gene name)|psi-mi:VPS5(display_short)|uniprotkb:GRD2(gene name synonym)|uniprotkb:PEP10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 5(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 10(gene name synonym)|uniprotkb:VPT5(gene name synonym)|uniprotkb:YOR29-20(orf name)|uniprotkb:YOR069W(locus name) psi-mi:vps35_yeast(display_long)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:Vacuolar protein-targeting protein 7(gene name synonym)|uniprotkb:VPT7(gene name synonym)|uniprotkb:J0580(orf name)|uniprotkb:YJL154C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348968|imex:IM-14275-3185 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014712.2|sgd:S000005595|ensemblfungi:YOR069W(gene)|ensemblfungi:YOR069W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0005768"(endosome)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|interpro:IPR001683(Phox-like)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028648|interpro:IPR035803|interpro:IPR036871|interpro:IPR037868|dip:DIP-1740N|mint:Q92331 refseq:NP_012381.1|sgd:S000003690|ensemblfungi:YJL154C(gene)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1904377"(positive regulation of protein localization to cell periphery)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR042491|reactome:R-SCE-3238698|ensemblfungi:YJL154C_mRNA(transcript)|dip:DIP-1743N|mint:P34110 psi-mi:"MI:0469"(intact) - crc64:DE1BC57B9DFB606E figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5aPSkQUJV1sfIc9Ql+wMP74Y3QI559292 rogid:5KBi/lSF+BsMyg9ulP9eLCp2xCc559292 intact-crc:CC8B9413F48B7F70|rigid:ZBMmFPbxBT13yMoqkE82iYcfCXs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92331 uniprotkb:P40335 intact:EBI-20483|uniprotkb:Q08483|uniprotkb:D6W2D1|uniprotkb:E9P8U6|ensemblfungi:YOR069W intact:EBI-20373|uniprotkb:D6VWC9|intact:EBI-3674163|uniprotkb:E9P910|ensemblfungi:YJL053W psi-mi:vps5_yeast(display_long)|uniprotkb:VPS5(gene name)|psi-mi:VPS5(display_short)|uniprotkb:GRD2(gene name synonym)|uniprotkb:PEP10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 5(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 10(gene name synonym)|uniprotkb:VPT5(gene name synonym)|uniprotkb:YOR29-20(orf name)|uniprotkb:YOR069W(locus name) psi-mi:pep8_yeast(display_long)|uniprotkb:PEP8(gene name)|psi-mi:PEP8(display_short)|uniprotkb:GRD6(gene name synonym)|uniprotkb:VPS26(gene name synonym)|uniprotkb:VPT4(gene name synonym)|uniprotkb:J1152(orf name)|uniprotkb:YJL053W(locus name)|uniprotkb:Vacuolar protein-targeting protein 4(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 26(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348980|imex:IM-14275-3186 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014712.2|sgd:S000005595|ensemblfungi:YOR069W(gene)|ensemblfungi:YOR069W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0005768"(endosome)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|interpro:IPR001683(Phox-like)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028648|interpro:IPR035803|interpro:IPR036871|interpro:IPR037868|dip:DIP-1740N|mint:Q92331 refseq:NP_012482.1|sgd:S000003589|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0140318"(protein transporter activity)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR028934|reactome:R-SCE-3238698|ensemblfungi:YJL053W(gene)|ensemblfungi:YJL053W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|dip:DIP-4572N|mint:P40335 psi-mi:"MI:0469"(intact) - crc64:40D15594E70A9B58 figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5aPSkQUJV1sfIc9Ql+wMP74Y3QI559292 rogid:mwZb20cO8nZl8hVUSRXAB5Varg0559292 intact-crc:935D130D92671D13|rigid:oIdJRXWaTSd13iakFGPFzTFs9FM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03860 uniprotkb:Q92331 intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W intact:EBI-20483|uniprotkb:Q08483|uniprotkb:D6W2D1|uniprotkb:E9P8U6|ensemblfungi:YOR069W psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym) psi-mi:vps5_yeast(display_long)|uniprotkb:VPS5(gene name)|psi-mi:VPS5(display_short)|uniprotkb:GRD2(gene name synonym)|uniprotkb:PEP10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 5(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 10(gene name synonym)|uniprotkb:VPT5(gene name synonym)|uniprotkb:YOR29-20(orf name)|uniprotkb:YOR069W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6348991|imex:IM-14275-3187 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated) refseq:NP_014712.2|sgd:S000005595|ensemblfungi:YOR069W(gene)|ensemblfungi:YOR069W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0005768"(endosome)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|interpro:IPR001683(Phox-like)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028648|interpro:IPR035803|interpro:IPR036871|interpro:IPR037868|dip:DIP-1740N|mint:Q92331 psi-mi:"MI:0469"(intact) crc64:395F700FBB14C569 - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292 rogid:5aPSkQUJV1sfIc9Ql+wMP74Y3QI559292 intact-crc:EE39CFFBA7F95A33|rigid:PoGRR8GvfnpdpurDxli85IQs3LI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92331 uniprotkb:Q92331 intact:EBI-20483|uniprotkb:Q08483|uniprotkb:D6W2D1|uniprotkb:E9P8U6|ensemblfungi:YOR069W intact:EBI-20483|uniprotkb:Q08483|uniprotkb:D6W2D1|uniprotkb:E9P8U6|ensemblfungi:YOR069W psi-mi:vps5_yeast(display_long)|uniprotkb:VPS5(gene name)|psi-mi:VPS5(display_short)|uniprotkb:GRD2(gene name synonym)|uniprotkb:PEP10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 5(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 10(gene name synonym)|uniprotkb:VPT5(gene name synonym)|uniprotkb:YOR29-20(orf name)|uniprotkb:YOR069W(locus name) psi-mi:vps5_yeast(display_long)|uniprotkb:VPS5(gene name)|psi-mi:VPS5(display_short)|uniprotkb:GRD2(gene name synonym)|uniprotkb:PEP10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 5(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 10(gene name synonym)|uniprotkb:VPT5(gene name synonym)|uniprotkb:YOR29-20(orf name)|uniprotkb:YOR069W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6349002|imex:IM-14275-3188 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014712.2|sgd:S000005595|ensemblfungi:YOR069W(gene)|ensemblfungi:YOR069W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0005768"(endosome)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|interpro:IPR001683(Phox-like)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028648|interpro:IPR035803|interpro:IPR036871|interpro:IPR037868|dip:DIP-1740N|mint:Q92331 refseq:NP_014712.2|sgd:S000005595|ensemblfungi:YOR069W(gene)|ensemblfungi:YOR069W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0005768"(endosome)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045053"(protein retention in Golgi apparatus)|interpro:IPR001683(Phox-like)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028648|interpro:IPR035803|interpro:IPR036871|interpro:IPR037868|dip:DIP-1740N|mint:Q92331 psi-mi:"MI:0469"(intact) - - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:5aPSkQUJV1sfIc9Ql+wMP74Y3QI559292 rogid:5aPSkQUJV1sfIc9Ql+wMP74Y3QI559292 intact-crc:67FB78327B8D41DC|rigid:JDu03hEBYRllB/9mh688CUe6uvw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08979 uniprotkb:Q99216 intact:EBI-9638|ensemblfungi:YPL263C|uniprotkb:D6W3A7 intact:EBI-31176|uniprotkb:Q02462|uniprotkb:Q7LHP7|uniprotkb:D6W2K3|ensemblfungi:YOR145C psi-mi:kel3_yeast(display_long)|uniprotkb:KEL3(gene name)|psi-mi:KEL3(display_short)|uniprotkb:YPL263C(locus name) psi-mi:pno1_yeast(display_long)|uniprotkb:PNO1(gene name)|psi-mi:PNO1(display_short)|uniprotkb:DIM2(gene name synonym)|uniprotkb:Partner of NOB1(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 20(gene name synonym)|uniprotkb:RRP20(gene name synonym)|uniprotkb:O3513(orf name)|uniprotkb:YOR3513C(orf name)|uniprotkb:YOR145C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6349013|imex:IM-14275-3189 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL263C(gene)|go:"GO:0005737"(cytoplasm)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR025183|ensemblfungi:YPL263C_mRNA(transcript)|refseq:NP_015060.1|sgd:S000006184|dip:DIP-3926N|mint:Q08979 refseq:NP_014788.1|sgd:S000005671|ensemblfungi:YOR145C(gene)|dip:DIP-4687N|mint:Q99216|ensemblfungi:YOR145C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030686"(90S preribosome)|go:"GO:0043248"(proteasome assembly)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR036612|interpro:IPR039912|interpro:IPR041174|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6EML|rcsb pdb:6FAI|rcsb pdb:6RBD|rcsb pdb:6Y7C|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 psi-mi:"MI:0469"(intact) - crc64:F61E17CAB85BF60C figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:uMF7Wf2cxn5RlDULmgxzx2h59DE559292 rogid:LrIcmLyg7x6mf92Uwfc47fL039k559292 intact-crc:F1B981314811E10B|rigid:69ejv8eblm4/GeHnnXooKQha7Iw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99260 uniprotkb:P32864 intact:EBI-29503|uniprotkb:D6VYQ8|ensemblfungi:YLR262C intact:EBI-14799|uniprotkb:Q06761|uniprotkb:D6W363|ensemblfungi:YOR370C psi-mi:ypt6_yeast(display_long)|uniprotkb:L8479.11(orf name)|uniprotkb:YLR262C(locus name)|uniprotkb:YPT6(gene name)|psi-mi:YPT6(display_short) psi-mi:raep_yeast(display_long)|uniprotkb:YOR370C(locus name)|uniprotkb:MRS6(gene name)|psi-mi:MRS6(display_short)|uniprotkb:MSI4(gene name synonym)|uniprotkb:Rab escort protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6349024|imex:IM-14275-3190 author score:98.73 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013363.1|sgd:S000004252|dip:DIP-5577N|mint:Q99260|ensemblfungi:YLR262C(gene)|ensemblfungi:YLR262C_mRNA(transcript)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-SCE-6798695|reactome:R-SCE-6811440|reactome:R-SCE-8873719|reactome:R-SCE-8876198 refseq:NP_015015.1|sgd:S000005897|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005968"(Rab-protein geranylgeranyltransferase complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR017230(Rab protein geranylgeranyltransferase, component A, fungi)|interpro:IPR018203|interpro:IPR036188|reactome:R-SCE-6803205|reactome:R-SCE-8873719|reactome:R-SCE-8876198|ensemblfungi:YOR370C(gene)|ensemblfungi:YOR370C_mRNA(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|dip:DIP-2246N|mint:P32864 psi-mi:"MI:0469"(intact) crc64:A8E6211FF24FAE0B crc64:30BB7FFF8D712FFD figure legend:tables S3 and S4|author-confidence:98.73|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:J/SeVhLd4mnvD5QEdkpsXWUH1rU559292 rogid:quu5u+3WZxRJAobk3H2EERRUqKU559292 intact-crc:08CE3AF28CEA3A4D|rigid:vt8jyRzZu9mmCRnE7wQqmjvaou0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39958 uniprotkb:Q99260 intact:EBI-7517|uniprotkb:D3DM41|ensemblfungi:YER136W intact:EBI-29503|uniprotkb:D6VYQ8|ensemblfungi:YLR262C psi-mi:gdi1_yeast(display_long)|uniprotkb:YER136W(locus name)|uniprotkb:GDI1(gene name)|psi-mi:GDI1(display_short)|uniprotkb:SEC19(gene name synonym)|uniprotkb:Secretory pathway GDP dissociation inhibitor(gene name synonym) psi-mi:ypt6_yeast(display_long)|uniprotkb:L8479.11(orf name)|uniprotkb:YLR262C(locus name)|uniprotkb:YPT6(gene name)|psi-mi:YPT6(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6349035|imex:IM-14275-3191 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011062.1|sgd:S000000938|mint:P39958|dip:DIP-785N|ensemblfungi:YER136W(gene)|ensemblfungi:YER136W_mRNA(transcript)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|rcsb pdb:1UKV|rcsb pdb:2BCG|rcsb pdb:3CPH|rcsb pdb:3CPI|rcsb pdb:3CPJ|reactome:R-SCE-6798695|reactome:R-SCE-8876198 refseq:NP_013363.1|sgd:S000004252|dip:DIP-5577N|mint:Q99260|ensemblfungi:YLR262C(gene)|ensemblfungi:YLR262C_mRNA(transcript)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-SCE-6798695|reactome:R-SCE-6811440|reactome:R-SCE-8873719|reactome:R-SCE-8876198 psi-mi:"MI:0469"(intact) crc64:48CF8D45FC031772 crc64:A8E6211FF24FAE0B figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:AkWsG1VUBGxajiAMw0e0mOljZ6s559292 rogid:J/SeVhLd4mnvD5QEdkpsXWUH1rU559292 intact-crc:1274C57E9EB386A8|rigid:UUKG2LlvRpy3oaw279kyf0LpmJw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99287 uniprotkb:P10614 intact:EBI-37523|uniprotkb:D6W2M3|ensemblfungi:YOR165W intact:EBI-5127|uniprotkb:D3DKV1|ensemblfungi:YHR007C psi-mi:sey1_yeast(display_long)|uniprotkb:SEY1(gene name)|psi-mi:SEY1(display_short)|uniprotkb:YOR165W(locus name)|uniprotkb:Synthetic enhancer of YOP1 protein(gene name synonym)|uniprotkb:O3590(orf name) psi-mi:cp51_yeast(display_long)|uniprotkb:ERG11(gene name)|psi-mi:ERG11(display_short)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450-LIA1(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:Cytochrome P450 51(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:YHR007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6349046|imex:IM-14275-3192 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014808.1|sgd:S000005691|dip:DIP-49373N|mint:Q99287|ensemblfungi:YOR165W(gene)|ensemblfungi:YOR165W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0061024"(membrane organization)|go:"GO:0071944"(cell periphery)|interpro:IPR008803(Root hair defective 3 GTP-binding)|interpro:IPR027417|interpro:IPR030386 refseq:NP_011871.1|sgd:S000001049|dip:DIP-7886N|mint:P10614|ensemblfungi:YHR007C(gene)|ensemblfungi:YHR007C_mRNA(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4LXJ|rcsb pdb:5EQB|reactome:R-SCE-191273|reactome:R-SCE-211976 psi-mi:"MI:0469"(intact) crc64:DEC0C9EC3AB172DF - figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zFsgalfyUvAuuV51vChJjraiQmI559292 rogid:R1GrAV+7O8sKd+9XaZrXHg7H+h8559292 intact-crc:6266EC6F4C683BB7|rigid:wQxRKzBsAcZtXlVf5hzUi4OaA3Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53337 uniprotkb:Q99287 intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C intact:EBI-37523|uniprotkb:D6W2M3|ensemblfungi:YOR165W psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name) psi-mi:sey1_yeast(display_long)|uniprotkb:SEY1(gene name)|psi-mi:SEY1(display_short)|uniprotkb:YOR165W(locus name)|uniprotkb:Synthetic enhancer of YOP1 protein(gene name synonym)|uniprotkb:O3590(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6349057|imex:IM-14275-3193 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434 refseq:NP_014808.1|sgd:S000005691|dip:DIP-49373N|mint:Q99287|ensemblfungi:YOR165W(gene)|ensemblfungi:YOR165W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0061024"(membrane organization)|go:"GO:0071944"(cell periphery)|interpro:IPR008803(Root hair defective 3 GTP-binding)|interpro:IPR027417|interpro:IPR030386 psi-mi:"MI:0469"(intact) - crc64:DEC0C9EC3AB172DF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292 rogid:zFsgalfyUvAuuV51vChJjraiQmI559292 intact-crc:6202C37C068E250B|rigid:/dSKRLvs9FQ681dfRt+tztPoi5o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54837 uniprotkb:Q99287 intact:EBI-6642|uniprotkb:D6VZG2|ensemblfungi:YML012W intact:EBI-37523|uniprotkb:D6W2M3|ensemblfungi:YOR165W psi-mi:tmeda_yeast(display_long)|uniprotkb:ERV25(gene name)|psi-mi:ERV25(display_short)|uniprotkb:YM9571.06(orf name)|uniprotkb:YML012W(locus name) psi-mi:sey1_yeast(display_long)|uniprotkb:SEY1(gene name)|psi-mi:SEY1(display_short)|uniprotkb:YOR165W(locus name)|uniprotkb:Synthetic enhancer of YOP1 protein(gene name synonym)|uniprotkb:O3590(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6349068|imex:IM-14275-3194 author score:99.30 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013701.1|sgd:S000004473|mint:P54837|dip:DIP-2134N|ensemblfungi:YML012W(gene)|ensemblfungi:YML012W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434 refseq:NP_014808.1|sgd:S000005691|dip:DIP-49373N|mint:Q99287|ensemblfungi:YOR165W(gene)|ensemblfungi:YOR165W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0061024"(membrane organization)|go:"GO:0071944"(cell periphery)|interpro:IPR008803(Root hair defective 3 GTP-binding)|interpro:IPR027417|interpro:IPR030386 psi-mi:"MI:0469"(intact) - crc64:DEC0C9EC3AB172DF figure legend:tables S3 and S4|author-confidence:99.30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:H4bQL5k77CB85Hz+8rjJcSAG/98559292 rogid:zFsgalfyUvAuuV51vChJjraiQmI559292 intact-crc:67B0E68B06A6167F|rigid:0QHJiqBB5LKJQ0oERsYscUMH8So false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99287 uniprotkb:Q99287 intact:EBI-37523|uniprotkb:D6W2M3|ensemblfungi:YOR165W intact:EBI-37523|uniprotkb:D6W2M3|ensemblfungi:YOR165W psi-mi:sey1_yeast(display_long)|uniprotkb:SEY1(gene name)|psi-mi:SEY1(display_short)|uniprotkb:YOR165W(locus name)|uniprotkb:Synthetic enhancer of YOP1 protein(gene name synonym)|uniprotkb:O3590(orf name) psi-mi:sey1_yeast(display_long)|uniprotkb:SEY1(gene name)|psi-mi:SEY1(display_short)|uniprotkb:YOR165W(locus name)|uniprotkb:Synthetic enhancer of YOP1 protein(gene name synonym)|uniprotkb:O3590(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Tarassov et al. (2008) pubmed:18467557|mint:MINT-6673767|imex:IM-14275 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6349079|imex:IM-14275-3195 author score:99.00 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014808.1|sgd:S000005691|dip:DIP-49373N|mint:Q99287|ensemblfungi:YOR165W(gene)|ensemblfungi:YOR165W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0061024"(membrane organization)|go:"GO:0071944"(cell periphery)|interpro:IPR008803(Root hair defective 3 GTP-binding)|interpro:IPR027417|interpro:IPR030386 refseq:NP_014808.1|sgd:S000005691|dip:DIP-49373N|mint:Q99287|ensemblfungi:YOR165W(gene)|ensemblfungi:YOR165W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0061024"(membrane organization)|go:"GO:0071944"(cell periphery)|interpro:IPR008803(Root hair defective 3 GTP-binding)|interpro:IPR027417|interpro:IPR030386 psi-mi:"MI:0469"(intact) crc64:DEC0C9EC3AB172DF crc64:DEC0C9EC3AB172DF figure legend:tables S3 and S4|author-confidence:99.00|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/14 2014/10/16 rogid:zFsgalfyUvAuuV51vChJjraiQmI559292 rogid:zFsgalfyUvAuuV51vChJjraiQmI559292 intact-crc:B6AA4CB653AAC630|rigid:A3kOCRBnLwZWqPz7yuwJgfK+vOg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)